This software is licensed to bgold@natera.com by Sentieon Inc.
cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1029_BICJ-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 1977.829 CPU sec, 72.880 real sec
[M::process] read 728308 sequences (100000028 bp) in 1.397 CPU sec, 1.404 real sec...
[M::process] read 727412 sequences (100000117 bp) in 1.865 CPU sec, 1.873 real sec...
[M::process] read 726272 sequences (100000055 bp) in 1.661 CPU sec, 1.663 real sec...
[M::process] read 725942 sequences (100000204 bp) in 1.848 CPU sec, 1.868 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (102, 287030, 65, 95)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (279, 631, 1595)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4227)
[M::mem_pestat] mean and std.dev: (785.32, 747.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5543)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 505)
[M::mem_pestat] mean and std.dev: (199.26, 91.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 630)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 954, 1722)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4864)
[M::mem_pestat] mean and std.dev: (927.44, 934.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6435)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 430, 1117)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2957)
[M::mem_pestat] mean and std.dev: (665.87, 684.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3877)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 726272 reads in 129.245 CPU sec, 4.145 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 288490, 70, 94)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 290, 762)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1874)
[M::mem_pestat] mean and std.dev: (470.75, 402.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2430)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 178, 250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 494)
[M::mem_pestat] mean and std.dev: (195.74, 88.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 616)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 612, 1258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3432)
[M::mem_pestat] mean and std.dev: (721.63, 721.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4519)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 393, 746)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1730)
[M::mem_pestat] mean and std.dev: (484.74, 375.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2222)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (99, 287665, 73, 106)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 393, 1424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3802)
[M::mem_pestat] mean and std.dev: (760.97, 735.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4991)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 180, 253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 501)
[M::mem_pestat] mean and std.dev: (197.86, 90.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 625)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (289, 582, 1437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3733)
[M::mem_pestat] mean and std.dev: (846.79, 704.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4881)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 408, 651)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1495)
[M::mem_pestat] mean and std.dev: (459.63, 313.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1917)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726240 sequences (100000258 bp) in 2.172 CPU sec, 2.232 real sec...
[M::mem_process_seqs] Processed 728308 reads in 375.104 CPU sec, 11.927 real sec
sorting block 0, #reads = 1080007 mem = 536882438 peak = 590659584
[M::mem_process_seqs] Processed 727412 reads in 289.545 CPU sec, 9.297 real sec
sorting block 1, #reads = 1081299 mem = 536879564 peak = 765247488
[M::process] read 725790 sequences (100000212 bp) in 2.769 CPU sec, 2.938 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (120, 287391, 69, 89)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 326, 998)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2654)
[M::mem_pestat] mean and std.dev: (510.79, 471.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3482)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 505)
[M::mem_pestat] mean and std.dev: (199.58, 91.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 630)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 549, 1288)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3528)
[M::mem_pestat] mean and std.dev: (743.03, 878.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4648)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (314, 667, 1544)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4004)
[M::mem_pestat] mean and std.dev: (925.41, 796.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5234)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724690 sequences (100000029 bp) in 1.961 CPU sec, 2.129 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (85, 287522, 69, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 325, 934)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2454)
[M::mem_pestat] mean and std.dev: (497.62, 484.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3214)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 511)
[M::mem_pestat] mean and std.dev: (200.46, 92.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 638)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 636, 1760)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4768)
[M::mem_pestat] mean and std.dev: (1100.03, 1157.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6272)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 435, 617)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1431)
[M::mem_pestat] mean and std.dev: (435.32, 291.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1838)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 725942 reads in 223.388 CPU sec, 7.331 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (102, 287716, 84, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (252, 436, 919)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2253)
[M::mem_pestat] mean and std.dev: (521.58, 389.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2920)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 508)
[M::mem_pestat] mean and std.dev: (200.11, 92.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 634)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (126, 430, 1019)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2805)
[M::mem_pestat] mean and std.dev: (582.01, 640.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3698)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 315, 1074)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2830)
[M::mem_pestat] mean and std.dev: (557.41, 536.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3708)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724574 sequences (100000025 bp) in 2.108 CPU sec, 2.185 real sec...
[M::mem_process_seqs] Processed 725790 reads in 250.699 CPU sec, 7.992 real sec
sorting block 2, #reads = 1078707 mem = 536878366 peak = 765247488
[M::mem_process_seqs] Processed 726240 reads in 283.733 CPU sec, 9.371 real sec
sorting block 3, #reads = 1079518 mem = 536883850 peak = 765247488
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (93, 287182, 72, 111)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 401, 851)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2147)
[M::mem_pestat] mean and std.dev: (477.11, 381.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2795)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 515)
[M::mem_pestat] mean and std.dev: (202.02, 93.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 643)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (340, 768, 2215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5965)
[M::mem_pestat] mean and std.dev: (1216.01, 1243.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7840)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 581, 1429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3849)
[M::mem_pestat] mean and std.dev: (909.25, 867.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5059)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724480 sequences (100000028 bp) in 3.199 CPU sec, 3.390 real sec...
[M::process] read 723756 sequences (100000280 bp) in 1.828 CPU sec, 1.835 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (99, 286900, 51, 98)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 848, 2612)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7390)
[M::mem_pestat] mean and std.dev: (1509.00, 1698.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9779)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 515)
[M::mem_pestat] mean and std.dev: (202.27, 93.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 643)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (369, 680, 2244)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5994)
[M::mem_pestat] mean and std.dev: (1123.28, 1310.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7869)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 287, 694)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1642)
[M::mem_pestat] mean and std.dev: (429.38, 364.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2116)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724690 reads in 229.539 CPU sec, 7.597 real sec
[M::mem_process_seqs] Processed 724574 reads in 156.721 CPU sec, 4.998 real sec
sorting block 4, #reads = 1078341 mem = 536879719 peak = 765247488
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 286373, 74, 104)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 346, 745)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1859)
[M::mem_pestat] mean and std.dev: (440.61, 358.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2416)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 515)
[M::mem_pestat] mean and std.dev: (202.22, 93.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 643)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (126, 609, 1238)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3462)
[M::mem_pestat] mean and std.dev: (693.65, 696.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4574)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 375, 1073)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2767)
[M::mem_pestat] mean and std.dev: (624.68, 601.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3614)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724086 sequences (100000119 bp) in 2.602 CPU sec, 2.710 real sec...
[M::process] read 724192 sequences (100000184 bp) in 2.127 CPU sec, 2.132 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (108, 286427, 70, 99)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 524, 978)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2564)
[M::mem_pestat] mean and std.dev: (623.90, 518.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3357)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 515)
[M::mem_pestat] mean and std.dev: (202.25, 93.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 643)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (303, 936, 1598)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4188)
[M::mem_pestat] mean and std.dev: (962.50, 989.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5483)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 365, 1018)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2650)
[M::mem_pestat] mean and std.dev: (616.50, 645.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3466)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724480 reads in 230.663 CPU sec, 7.465 real sec
[M::mem_process_seqs] Processed 723756 reads in 160.797 CPU sec, 5.318 real sec
sorting block 5, #reads = 1078420 mem = 536883734 peak = 765247488
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (97, 286523, 86, 99)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 459, 1733)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4737)
[M::mem_pestat] mean and std.dev: (945.64, 1027.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6239)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 512)
[M::mem_pestat] mean and std.dev: (201.41, 92.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 639)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (327, 766, 1261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3129)
[M::mem_pestat] mean and std.dev: (751.19, 619.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4063)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 355, 865)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2143)
[M::mem_pestat] mean and std.dev: (523.03, 452.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2782)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724268 sequences (100000002 bp) in 3.027 CPU sec, 3.213 real sec...
[M::process] read 723914 sequences (100000222 bp) in 2.339 CPU sec, 2.347 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (90, 286778, 95, 92)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 397, 977)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2489)
[M::mem_pestat] mean and std.dev: (628.54, 562.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3245)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 509)
[M::mem_pestat] mean and std.dev: (201.19, 91.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 635)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (252, 605, 1542)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4122)
[M::mem_pestat] mean and std.dev: (804.37, 683.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5412)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 404, 970)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2442)
[M::mem_pestat] mean and std.dev: (590.81, 526.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3178)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724086 reads in 241.072 CPU sec, 7.845 real sec
sorting block 6, #reads = 1077032 mem = 536879161 peak = 765247488
[M::mem_process_seqs] Processed 724192 reads in 162.754 CPU sec, 5.317 real sec
sorting block 7, #reads = 1077648 mem = 536881070 peak = 805048320
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (87, 286544, 62, 119)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 584, 1259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3337)
[M::mem_pestat] mean and std.dev: (752.62, 723.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4376)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 512)
[M::mem_pestat] mean and std.dev: (201.56, 92.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 639)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 433, 980)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2582)
[M::mem_pestat] mean and std.dev: (584.57, 525.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3383)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 442, 989)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2609)
[M::mem_pestat] mean and std.dev: (554.32, 497.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3419)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723322 sequences (100000275 bp) in 2.906 CPU sec, 3.032 real sec...
[M::process] read 723278 sequences (100000261 bp) in 1.851 CPU sec, 1.866 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 287243, 72, 98)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (252, 479, 1403)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3705)
[M::mem_pestat] mean and std.dev: (703.58, 670.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4856)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 515)
[M::mem_pestat] mean and std.dev: (202.23, 93.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 643)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 408, 931)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2371)
[M::mem_pestat] mean and std.dev: (523.09, 408.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3091)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 529, 1056)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2680)
[M::mem_pestat] mean and std.dev: (764.24, 668.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3492)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724268 reads in 249.395 CPU sec, 8.111 real sec
[M::mem_process_seqs] Processed 723914 reads in 160.506 CPU sec, 5.200 real sec
sorting block 8, #reads = 1078292 mem = 536880255 peak = 805048320
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (115, 286077, 64, 92)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (308, 468, 1428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3668)
[M::mem_pestat] mean and std.dev: (845.13, 864.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4788)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 184, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 513)
[M::mem_pestat] mean and std.dev: (202.35, 92.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 640)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 502, 1186)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3220)
[M::mem_pestat] mean and std.dev: (719.81, 731.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4237)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (259, 631, 1093)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2761)
[M::mem_pestat] mean and std.dev: (636.54, 472.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3595)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721774 sequences (100000038 bp) in 3.303 CPU sec, 3.487 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (105, 286166, 58, 98)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 443, 1281)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3419)
[M::mem_pestat] mean and std.dev: (725.62, 749.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4488)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 184, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 516)
[M::mem_pestat] mean and std.dev: (202.90, 93.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 644)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (501, 1081, 2957)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7869)
[M::mem_pestat] mean and std.dev: (1950.11, 2065.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10325)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (275, 525, 1188)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3014)
[M::mem_pestat] mean and std.dev: (713.75, 610.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3927)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722686 sequences (100000145 bp) in 1.899 CPU sec, 1.901 real sec...
[M::mem_process_seqs] Processed 723322 reads in 237.416 CPU sec, 7.668 real sec
[M::mem_process_seqs] Processed 723278 reads in 171.540 CPU sec, 5.492 real sec
sorting block 9, #reads = 1078394 mem = 536882062 peak = 805048320
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (105, 286017, 85, 125)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 408, 1044)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2722)
[M::mem_pestat] mean and std.dev: (606.45, 547.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3561)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 186, 264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 526)
[M::mem_pestat] mean and std.dev: (205.80, 95.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 657)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 405, 1167)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3173)
[M::mem_pestat] mean and std.dev: (691.13, 730.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4176)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 301, 1067)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2841)
[M::mem_pestat] mean and std.dev: (647.40, 689.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3728)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722174 sequences (100000195 bp) in 3.682 CPU sec, 3.909 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (109, 286102, 64, 98)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 511, 1569)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4267)
[M::mem_pestat] mean and std.dev: (954.80, 1008.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5616)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 522)
[M::mem_pestat] mean and std.dev: (204.27, 93.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 652)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 772, 1941)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5351)
[M::mem_pestat] mean and std.dev: (1158.82, 1273.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7056)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 477, 1262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3382)
[M::mem_pestat] mean and std.dev: (710.49, 731.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4442)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721616 sequences (100000000 bp) in 2.720 CPU sec, 2.712 real sec...
[M::mem_process_seqs] Processed 721774 reads in 231.853 CPU sec, 7.369 real sec
sorting block 10, #reads = 1075933 mem = 536878698 peak = 805048320
[M::process] read 721380 sequences (100000004 bp) in 2.581 CPU sec, 2.588 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (101, 285850, 67, 103)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 481, 965)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2447)
[M::mem_pestat] mean and std.dev: (628.65, 579.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3188)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 186, 263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 525)
[M::mem_pestat] mean and std.dev: (204.96, 94.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 656)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 487, 1170)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3074)
[M::mem_pestat] mean and std.dev: (532.88, 447.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4026)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 375, 865)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2195)
[M::mem_pestat] mean and std.dev: (459.67, 351.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2860)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 722174 reads in 127.256 CPU sec, 4.342 real sec
sorting block 11, #reads = 1076780 mem = 536880532 peak = 886534144
[M::mem_process_seqs] Processed 722686 reads in 337.904 CPU sec, 11.067 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (114, 285654, 75, 90)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 361, 788)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2024)
[M::mem_pestat] mean and std.dev: (462.58, 395.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2642)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 187, 263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 523)
[M::mem_pestat] mean and std.dev: (205.55, 94.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 653)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 675, 1144)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2954)
[M::mem_pestat] mean and std.dev: (788.96, 686.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3859)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 463, 1171)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3033)
[M::mem_pestat] mean and std.dev: (702.58, 655.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3964)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721296 sequences (100000067 bp) in 3.479 CPU sec, 3.747 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (113, 286122, 72, 111)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 501, 1195)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3205)
[M::mem_pestat] mean and std.dev: (618.59, 581.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4210)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 187, 265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 529)
[M::mem_pestat] mean and std.dev: (206.52, 95.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 661)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 521, 1235)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3377)
[M::mem_pestat] mean and std.dev: (811.54, 947.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4603)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 363, 921)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2341)
[M::mem_pestat] mean and std.dev: (539.94, 484.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3051)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 721616 reads in 260.846 CPU sec, 8.362 real sec
sorting block 12, #reads = 1077045 mem = 536879840 peak = 886534144
[M::process] read 726538 sequences (100000285 bp) in 2.617 CPU sec, 2.650 real sec...
[M::mem_process_seqs] Processed 721380 reads in 165.666 CPU sec, 5.455 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (124, 285440, 89, 102)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 491, 1267)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3311)
[M::mem_pestat] mean and std.dev: (721.66, 684.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4333)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
sorting block 13, #reads = 1077441 mem = 536880516 peak = 886534144
[M::mem_pestat] (25, 50, 75) percentile: (133, 188, 266)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 532)
[M::mem_pestat] mean and std.dev: (206.95, 95.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 665)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 581, 1444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3924)
[M::mem_pestat] mean and std.dev: (785.72, 716.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5164)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 589, 991)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2469)
[M::mem_pestat] mean and std.dev: (611.44, 474.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3208)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727738 sequences (100000108 bp) in 3.560 CPU sec, 3.795 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (105, 287342, 58, 97)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 419, 1062)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2810)
[M::mem_pestat] mean and std.dev: (668.24, 616.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3684)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 505)
[M::mem_pestat] mean and std.dev: (199.30, 91.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 630)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 870, 1110)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2850)
[M::mem_pestat] mean and std.dev: (718.56, 526.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3720)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (266, 533, 1199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3065)
[M::mem_pestat] mean and std.dev: (701.58, 575.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3998)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727002 sequences (100000128 bp) in 2.662 CPU sec, 2.669 real sec...
[M::mem_process_seqs] Processed 721296 reads in 239.912 CPU sec, 7.844 real sec
[M::mem_process_seqs] Processed 726538 reads in 168.190 CPU sec, 5.383 real sec
sorting block 14, #reads = 1074902 mem = 536882180 peak = 886534144
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (94, 287905, 60, 104)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 410, 871)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2195)
[M::mem_pestat] mean and std.dev: (514.89, 458.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2857)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 498)
[M::mem_pestat] mean and std.dev: (197.23, 90.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 621)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (253, 650, 1397)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3685)
[M::mem_pestat] mean and std.dev: (794.55, 717.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4829)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 436, 1160)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3066)
[M::mem_pestat] mean and std.dev: (604.11, 525.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4019)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726754 sequences (100000000 bp) in 3.817 CPU sec, 4.067 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 287775, 73, 99)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 491, 1151)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3007)
[M::mem_pestat] mean and std.dev: (611.33, 648.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3935)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 180, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 504)
[M::mem_pestat] mean and std.dev: (198.52, 91.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 629)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (274, 532, 1387)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3613)
[M::mem_pestat] mean and std.dev: (780.00, 726.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4726)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 372, 1237)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3221)
[M::mem_pestat] mean and std.dev: (619.17, 587.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4213)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725782 sequences (100000034 bp) in 2.700 CPU sec, 2.702 real sec...
[M::mem_process_seqs] Processed 727738 reads in 235.817 CPU sec, 7.528 real sec
sorting block 15, #reads = 1079440 mem = 536881325 peak = 886534144
[M::mem_process_seqs] Processed 727002 reads in 163.938 CPU sec, 5.257 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (89, 288188, 51, 95)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 364, 711)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1801)
[M::mem_pestat] mean and std.dev: (403.86, 339.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2346)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 180, 255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 507)
[M::mem_pestat] mean and std.dev: (199.34, 92.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 633)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (399, 575, 1155)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2667)
[M::mem_pestat] mean and std.dev: (628.09, 460.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3423)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 472, 1295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3409)
[M::mem_pestat] mean and std.dev: (683.46, 596.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4466)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726082 sequences (100000067 bp) in 3.602 CPU sec, 3.764 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (101, 287525, 80, 95)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 434, 1873)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5147)
[M::mem_pestat] mean and std.dev: (870.01, 903.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6784)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 508)
[M::mem_pestat] mean and std.dev: (200.14, 92.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 634)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 760, 1315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3499)
[M::mem_pestat] mean and std.dev: (733.49, 615.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4591)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 306, 834)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2106)
[M::mem_pestat] mean and std.dev: (475.47, 404.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2742)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725346 sequences (100000158 bp) in 2.504 CPU sec, 2.513 real sec...
[M::mem_process_seqs] Processed 726754 reads in 234.624 CPU sec, 7.523 real sec
sorting block 16, #reads = 1080085 mem = 536882867 peak = 886534144
[M::mem_process_seqs] Processed 725782 reads in 160.738 CPU sec, 5.185 real sec
sorting block 17, #reads = 1080435 mem = 536880108 peak = 886534144
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 287146, 55, 105)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 354, 989)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2645)
[M::mem_pestat] mean and std.dev: (530.56, 499.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3473)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 508)
[M::mem_pestat] mean and std.dev: (200.30, 92.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 634)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 650, 1973)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5557)
[M::mem_pestat] mean and std.dev: (975.31, 862.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7349)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 322, 811)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2065)
[M::mem_pestat] mean and std.dev: (440.67, 408.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2692)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725122 sequences (100000048 bp) in 3.327 CPU sec, 3.434 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (110, 286831, 78, 107)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 489, 1147)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2977)
[M::mem_pestat] mean and std.dev: (760.58, 718.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3892)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 182, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 514)
[M::mem_pestat] mean and std.dev: (201.62, 93.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 642)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 454, 864)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2302)
[M::mem_pestat] mean and std.dev: (452.88, 400.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3021)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 529, 1049)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2717)
[M::mem_pestat] mean and std.dev: (679.46, 525.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3551)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724704 sequences (100000114 bp) in 2.658 CPU sec, 2.668 real sec...
[M::mem_process_seqs] Processed 726082 reads in 234.823 CPU sec, 7.564 real sec
[M::mem_process_seqs] Processed 725346 reads in 161.262 CPU sec, 5.254 real sec
sorting block 18, #reads = 1079218 mem = 536879294 peak = 886534144
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 286952, 87, 106)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 356, 717)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1719)
[M::mem_pestat] mean and std.dev: (427.33, 327.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2220)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 182, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 514)
[M::mem_pestat] mean and std.dev: (201.62, 93.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 642)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 541, 1103)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2963)
[M::mem_pestat] mean and std.dev: (634.64, 599.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3893)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (319, 593, 1226)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3040)
[M::mem_pestat] mean and std.dev: (666.96, 553.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3947)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724460 sequences (100000142 bp) in 3.935 CPU sec, 4.160 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (111, 286702, 77, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 396, 1010)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2636)
[M::mem_pestat] mean and std.dev: (547.05, 473.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3449)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 515)
[M::mem_pestat] mean and std.dev: (202.08, 93.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 643)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (128, 645, 1267)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3545)
[M::mem_pestat] mean and std.dev: (774.12, 779.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4684)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 371, 1006)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2622)
[M::mem_pestat] mean and std.dev: (567.15, 485.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3430)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724416 sequences (100000103 bp) in 2.129 CPU sec, 2.131 real sec...
[M::mem_process_seqs] Processed 725122 reads in 232.611 CPU sec, 7.546 real sec
sorting block 19, #reads = 1078892 mem = 536880982 peak = 886534144
[M::mem_process_seqs] Processed 724704 reads in 161.409 CPU sec, 5.249 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (102, 287139, 65, 115)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 374, 883)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2235)
[M::mem_pestat] mean and std.dev: (527.47, 484.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2911)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 182, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 515)
[M::mem_pestat] mean and std.dev: (201.99, 93.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 643)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 601, 1431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3863)
[M::mem_pestat] mean and std.dev: (807.24, 736.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5079)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 386, 714)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1702)
[M::mem_pestat] mean and std.dev: (510.78, 383.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2196)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 20, #reads = 1078010 mem = 536881135 peak = 886534144
[M::process] read 724504 sequences (100000026 bp) in 3.187 CPU sec, 3.327 real sec...
[M::process] read 725014 sequences (100000228 bp) in 2.462 CPU sec, 2.463 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (99, 286419, 63, 92)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 407, 703)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1801)
[M::mem_pestat] mean and std.dev: (430.41, 337.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2350)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 512)
[M::mem_pestat] mean and std.dev: (201.58, 92.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 639)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 530, 887)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2239)
[M::mem_pestat] mean and std.dev: (614.02, 513.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2915)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 373, 948)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2418)
[M::mem_pestat] mean and std.dev: (555.88, 505.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3153)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724460 reads in 232.246 CPU sec, 7.479 real sec
[M::mem_process_seqs] Processed 724416 reads in 161.601 CPU sec, 5.286 real sec
sorting block 21, #reads = 1079085 mem = 536882008 peak = 886534144
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (100, 286716, 84, 91)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 432, 1023)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2685)
[M::mem_pestat] mean and std.dev: (610.66, 584.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3516)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 182, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 506)
[M::mem_pestat] mean and std.dev: (200.57, 91.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 631)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (383, 791, 1358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3308)
[M::mem_pestat] mean and std.dev: (815.34, 625.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4283)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (289, 528, 1370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3532)
[M::mem_pestat] mean and std.dev: (807.41, 750.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4613)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724564 sequences (100000199 bp) in 3.821 CPU sec, 4.013 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (102, 286471, 63, 101)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 472, 1258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3326)
[M::mem_pestat] mean and std.dev: (714.40, 663.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4360)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 182, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 509)
[M::mem_pestat] mean and std.dev: (200.62, 92.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 635)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (392, 898, 1324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3188)
[M::mem_pestat] mean and std.dev: (857.45, 603.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4120)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 425, 1190)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3148)
[M::mem_pestat] mean and std.dev: (655.47, 626.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4127)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723702 sequences (100000230 bp) in 2.742 CPU sec, 2.747 real sec...
[M::mem_process_seqs] Processed 724504 reads in 231.110 CPU sec, 7.463 real sec
[M::mem_process_seqs] Processed 725014 reads in 161.208 CPU sec, 5.171 real sec
sorting block 22, #reads = 1077189 mem = 536888555 peak = 886534144
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (97, 286215, 56, 96)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 309, 816)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2106)
[M::mem_pestat] mean and std.dev: (471.07, 448.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2751)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 182, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 509)
[M::mem_pestat] mean and std.dev: (200.68, 91.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 635)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 592, 1342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3496)
[M::mem_pestat] mean and std.dev: (682.62, 597.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4573)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 499, 993)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2515)
[M::mem_pestat] mean and std.dev: (547.89, 419.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3276)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723606 sequences (100000144 bp) in 3.687 CPU sec, 3.869 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (120, 286000, 55, 100)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 411, 927)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2341)
[M::mem_pestat] mean and std.dev: (526.06, 411.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3048)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 515)
[M::mem_pestat] mean and std.dev: (202.25, 92.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 643)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (590, 923, 1340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2840)
[M::mem_pestat] mean and std.dev: (912.96, 618.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3590)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 368, 890)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2232)
[M::mem_pestat] mean and std.dev: (524.53, 465.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2903)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724564 reads in 233.148 CPU sec, 7.474 real sec
[M::process] read 723826 sequences (100000151 bp) in 2.724 CPU sec, 2.743 real sec...
sorting block 23, #reads = 1078004 mem = 536885296 peak = 886534144
[M::mem_process_seqs] Processed 723702 reads in 161.993 CPU sec, 5.360 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (89, 286893, 71, 106)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (324, 657, 1836)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4860)
[M::mem_pestat] mean and std.dev: (985.11, 1039.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6372)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 512)
[M::mem_pestat] mean and std.dev: (201.67, 92.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 639)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 864, 1995)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5581)
[M::mem_pestat] mean and std.dev: (1322.92, 1431.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7374)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (314, 468, 815)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1817)
[M::mem_pestat] mean and std.dev: (552.34, 388.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2318)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 24, #reads = 1077648 mem = 536879532 peak = 905056256
[M::process] read 723848 sequences (100000061 bp) in 3.779 CPU sec, 3.929 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (114, 286357, 78, 88)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (293, 693, 1296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3302)
[M::mem_pestat] mean and std.dev: (779.68, 606.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4305)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 515)
[M::mem_pestat] mean and std.dev: (202.20, 93.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 643)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 671, 1397)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3819)
[M::mem_pestat] mean and std.dev: (808.96, 845.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5030)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 320, 857)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2167)
[M::mem_pestat] mean and std.dev: (484.38, 442.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2822)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723606 reads in 225.181 CPU sec, 7.384 real sec
[M::process] read 723476 sequences (100000100 bp) in 2.872 CPU sec, 2.903 real sec...
[M::mem_process_seqs] Processed 723826 reads in 158.854 CPU sec, 5.111 real sec
sorting block 25, #reads = 1077066 mem = 536878095 peak = 905056256
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (95, 286591, 48, 113)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 446, 1210)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3206)
[M::mem_pestat] mean and std.dev: (680.22, 639.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4204)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 515)
[M::mem_pestat] mean and std.dev: (202.50, 93.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 643)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (33, 373, 710)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2064)
[M::mem_pestat] mean and std.dev: (359.11, 360.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2741)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 371, 956)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2366)
[M::mem_pestat] mean and std.dev: (487.17, 409.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3071)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723082 sequences (100000228 bp) in 3.837 CPU sec, 4.055 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (81, 286691, 67, 110)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 346, 726)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1710)
[M::mem_pestat] mean and std.dev: (462.64, 354.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2202)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 518)
[M::mem_pestat] mean and std.dev: (203.22, 93.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 647)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 454, 1002)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2698)
[M::mem_pestat] mean and std.dev: (578.72, 560.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3546)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 393, 915)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2243)
[M::mem_pestat] mean and std.dev: (598.63, 474.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2907)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721736 sequences (100000151 bp) in 2.640 CPU sec, 2.641 real sec...
[M::mem_process_seqs] Processed 723848 reads in 231.780 CPU sec, 7.437 real sec
[M::mem_process_seqs] Processed 723476 reads in 159.545 CPU sec, 5.206 real sec
sorting block 26, #reads = 1077564 mem = 536881623 peak = 905056256
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (99, 286322, 56, 101)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (255, 448, 1379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3627)
[M::mem_pestat] mean and std.dev: (700.15, 696.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4751)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 522)
[M::mem_pestat] mean and std.dev: (204.11, 94.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 652)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 633, 1326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3552)
[M::mem_pestat] mean and std.dev: (748.55, 664.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4665)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 435, 1143)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2973)
[M::mem_pestat] mean and std.dev: (620.17, 584.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3888)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722242 sequences (100000223 bp) in 3.868 CPU sec, 4.028 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (85, 285992, 75, 113)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 334, 578)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1400)
[M::mem_pestat] mean and std.dev: (372.66, 263.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1811)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 186, 263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 523)
[M::mem_pestat] mean and std.dev: (204.95, 94.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 653)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 832, 1477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4133)
[M::mem_pestat] mean and std.dev: (865.51, 732.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5461)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 380, 1109)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2881)
[M::mem_pestat] mean and std.dev: (619.21, 619.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3767)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723082 reads in 226.729 CPU sec, 7.374 real sec
[M::process] read 725488 sequences (100000078 bp) in 2.868 CPU sec, 2.911 real sec...
sorting block 27, #reads = 1076747 mem = 536878655 peak = 905056256
[M::mem_process_seqs] Processed 721736 reads in 164.022 CPU sec, 5.433 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (101, 285748, 76, 102)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 405, 1346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3556)
[M::mem_pestat] mean and std.dev: (786.15, 793.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4661)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 186, 264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 526)
[M::mem_pestat] mean and std.dev: (205.70, 95.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 657)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (384, 556, 1249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2979)
[M::mem_pestat] mean and std.dev: (744.54, 638.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3844)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 409, 1189)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3133)
[M::mem_pestat] mean and std.dev: (654.30, 604.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4105)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 28, #reads = 1077071 mem = 536878954 peak = 905056256
[M::process] read 727986 sequences (100000100 bp) in 3.505 CPU sec, 3.674 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (100, 286809, 60, 119)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 297, 948)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2500)
[M::mem_pestat] mean and std.dev: (513.21, 491.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3276)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 182, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 508)
[M::mem_pestat] mean and std.dev: (200.26, 92.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 634)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 613, 1104)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2830)
[M::mem_pestat] mean and std.dev: (632.89, 575.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3693)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 399, 1090)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2808)
[M::mem_pestat] mean and std.dev: (655.66, 600.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3667)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726758 sequences (100000126 bp) in 2.576 CPU sec, 2.583 real sec...
[M::mem_process_seqs] Processed 722242 reads in 236.636 CPU sec, 7.777 real sec
[M::mem_process_seqs] Processed 725488 reads in 167.252 CPU sec, 5.377 real sec
sorting block 29, #reads = 1074716 mem = 536880183 peak = 905056256
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (106, 288180, 84, 84)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 352, 818)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1980)
[M::mem_pestat] mean and std.dev: (465.70, 404.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2561)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 495)
[M::mem_pestat] mean and std.dev: (196.85, 89.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 617)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 575, 1217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3325)
[M::mem_pestat] mean and std.dev: (707.59, 715.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4379)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 514, 1107)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2915)
[M::mem_pestat] mean and std.dev: (656.71, 618.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3819)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726552 sequences (100000288 bp) in 3.537 CPU sec, 3.780 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (88, 287236, 63, 101)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 280, 594)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1444)
[M::mem_pestat] mean and std.dev: (407.01, 344.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1869)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 180, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 504)
[M::mem_pestat] mean and std.dev: (198.60, 90.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 629)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (93, 327, 1051)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2967)
[M::mem_pestat] mean and std.dev: (623.87, 726.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3925)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 466, 1595)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4275)
[M::mem_pestat] mean and std.dev: (810.90, 786.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5615)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725462 sequences (100000076 bp) in 2.809 CPU sec, 2.820 real sec...
[M::mem_process_seqs] Processed 727986 reads in 233.366 CPU sec, 7.481 real sec
[M::mem_process_seqs] Processed 726758 reads in 159.559 CPU sec, 5.071 real sec
sorting block 30, #reads = 1079118 mem = 536882995 peak = 905056256
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (95, 287078, 65, 119)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 523, 1133)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2921)
[M::mem_pestat] mean and std.dev: (683.74, 660.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3815)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 505)
[M::mem_pestat] mean and std.dev: (199.33, 91.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 630)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 331, 1398)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3862)
[M::mem_pestat] mean and std.dev: (800.95, 939.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5094)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (270, 450, 1251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3213)
[M::mem_pestat] mean and std.dev: (670.96, 560.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4194)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724906 sequences (100000259 bp) in 3.488 CPU sec, 3.642 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (118, 287810, 79, 113)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 514, 1406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3728)
[M::mem_pestat] mean and std.dev: (858.01, 909.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4889)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 182, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 511)
[M::mem_pestat] mean and std.dev: (200.58, 92.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 638)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 535, 1328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3606)
[M::mem_pestat] mean and std.dev: (724.41, 732.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4745)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 592, 1280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3352)
[M::mem_pestat] mean and std.dev: (772.63, 674.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4388)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724502 sequences (100000221 bp) in 2.675 CPU sec, 2.681 real sec...
[M::mem_process_seqs] Processed 726552 reads in 234.219 CPU sec, 7.466 real sec
sorting block 31, #reads = 1079817 mem = 536897542 peak = 905056256
[M::mem_process_seqs] Processed 725462 reads in 163.250 CPU sec, 5.216 real sec
sorting block 32, #reads = 1079369 mem = 536875596 peak = 954945536
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (91, 287019, 88, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 375, 918)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2306)
[M::mem_pestat] mean and std.dev: (638.03, 602.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3047)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 183, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 517)
[M::mem_pestat] mean and std.dev: (201.99, 93.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 646)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 448, 975)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2443)
[M::mem_pestat] mean and std.dev: (694.05, 681.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3419)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 516, 1087)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2849)
[M::mem_pestat] mean and std.dev: (613.30, 571.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3730)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724512 sequences (100000046 bp) in 3.510 CPU sec, 3.676 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (111, 287211, 63, 110)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 500, 1292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3408)
[M::mem_pestat] mean and std.dev: (674.87, 598.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4466)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 518)
[M::mem_pestat] mean and std.dev: (202.87, 93.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 647)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (315, 561, 1238)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3084)
[M::mem_pestat] mean and std.dev: (738.37, 780.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4007)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 393, 861)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2201)
[M::mem_pestat] mean and std.dev: (522.06, 446.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2871)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724290 sequences (100000212 bp) in 2.620 CPU sec, 2.625 real sec...
[M::mem_process_seqs] Processed 724906 reads in 230.368 CPU sec, 7.347 real sec
[M::mem_process_seqs] Processed 724502 reads in 160.142 CPU sec, 5.198 real sec
sorting block 33, #reads = 1078799 mem = 536879767 peak = 954945536
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (97, 286465, 67, 101)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 514, 1039)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2677)
[M::mem_pestat] mean and std.dev: (675.78, 634.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3496)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 518)
[M::mem_pestat] mean and std.dev: (202.61, 93.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 647)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 961, 1625)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4381)
[M::mem_pestat] mean and std.dev: (1101.61, 1045.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5759)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 430, 843)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2077)
[M::mem_pestat] mean and std.dev: (492.97, 377.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2694)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723956 sequences (100000037 bp) in 3.091 CPU sec, 3.222 real sec...
[M::process] read 724072 sequences (100000113 bp) in 2.339 CPU sec, 2.346 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (125, 286758, 72, 96)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 433, 1181)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3081)
[M::mem_pestat] mean and std.dev: (647.43, 610.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4031)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 515)
[M::mem_pestat] mean and std.dev: (202.21, 93.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 643)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 622, 905)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2325)
[M::mem_pestat] mean and std.dev: (651.58, 546.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3035)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 386, 1070)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2812)
[M::mem_pestat] mean and std.dev: (601.02, 511.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3683)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724512 reads in 233.167 CPU sec, 7.534 real sec
sorting block 34, #reads = 1078481 mem = 536887971 peak = 954945536
[M::mem_process_seqs] Processed 724290 reads in 162.512 CPU sec, 5.190 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (113, 287008, 70, 110)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 373, 881)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2297)
[M::mem_pestat] mean and std.dev: (504.53, 398.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3005)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 521)
[M::mem_pestat] mean and std.dev: (203.34, 94.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 651)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (384, 636, 1219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2889)
[M::mem_pestat] mean and std.dev: (740.22, 582.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3724)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 345, 802)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1970)
[M::mem_pestat] mean and std.dev: (510.85, 447.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2554)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 35, #reads = 1078240 mem = 536880173 peak = 954945536
[M::process] read 723682 sequences (100000206 bp) in 3.803 CPU sec, 3.975 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (114, 287341, 41, 123)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 339, 1398)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3800)
[M::mem_pestat] mean and std.dev: (641.03, 743.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5001)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 518)
[M::mem_pestat] mean and std.dev: (202.92, 94.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 647)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 684, 922)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2336)
[M::mem_pestat] mean and std.dev: (563.89, 382.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3043)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 477, 1509)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4121)
[M::mem_pestat] mean and std.dev: (822.16, 823.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5427)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723956 reads in 224.651 CPU sec, 7.147 real sec
[M::process] read 724308 sequences (100000118 bp) in 2.673 CPU sec, 2.688 real sec...
[M::mem_process_seqs] Processed 724072 reads in 157.989 CPU sec, 5.327 real sec
sorting block 36, #reads = 1079347 mem = 536877827 peak = 954945536
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (107, 286811, 85, 120)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 386, 916)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2260)
[M::mem_pestat] mean and std.dev: (530.20, 433.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2932)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 515)
[M::mem_pestat] mean and std.dev: (202.55, 93.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 643)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 533, 1036)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2642)
[M::mem_pestat] mean and std.dev: (650.70, 540.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3445)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (283, 463, 1480)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3874)
[M::mem_pestat] mean and std.dev: (889.18, 969.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5071)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723898 sequences (100000004 bp) in 3.408 CPU sec, 3.570 real sec...
[M::process] read 723674 sequences (100000106 bp) in 2.169 CPU sec, 2.173 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (99, 286893, 84, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (275, 444, 1223)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3119)
[M::mem_pestat] mean and std.dev: (665.43, 641.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4067)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 182, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 509)
[M::mem_pestat] mean and std.dev: (200.85, 91.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 635)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 415, 1339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3657)
[M::mem_pestat] mean and std.dev: (829.23, 902.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4816)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (261, 497, 1283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3327)
[M::mem_pestat] mean and std.dev: (758.14, 704.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4349)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723682 reads in 237.488 CPU sec, 7.867 real sec
[M::mem_process_seqs] Processed 724308 reads in 165.683 CPU sec, 5.289 real sec
sorting block 37, #reads = 1077590 mem = 536880493 peak = 954945536
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (113, 286350, 56, 132)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 559, 1101)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2791)
[M::mem_pestat] mean and std.dev: (615.25, 516.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3636)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 512)
[M::mem_pestat] mean and std.dev: (201.48, 92.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 639)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 458, 927)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2437)
[M::mem_pestat] mean and std.dev: (496.24, 493.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3192)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 396, 915)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2389)
[M::mem_pestat] mean and std.dev: (498.38, 451.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3126)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723766 sequences (100000061 bp) in 3.864 CPU sec, 4.040 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (136, 286334, 65, 94)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 381, 937)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2399)
[M::mem_pestat] mean and std.dev: (539.60, 460.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3130)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 183, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 513)
[M::mem_pestat] mean and std.dev: (202.06, 92.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 640)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 491, 1109)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2951)
[M::mem_pestat] mean and std.dev: (663.25, 624.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3872)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 361, 823)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2067)
[M::mem_pestat] mean and std.dev: (455.51, 375.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2689)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723538 sequences (100000024 bp) in 2.370 CPU sec, 2.365 real sec...
[M::mem_process_seqs] Processed 723898 reads in 236.412 CPU sec, 7.547 real sec
sorting block 38, #reads = 1076289 mem = 536881207 peak = 954945536
[M::mem_process_seqs] Processed 723674 reads in 163.875 CPU sec, 5.223 real sec
sorting block 39, #reads = 1076349 mem = 536880295 peak = 954945536
[M::process] read 723126 sequences (100000285 bp) in 3.717 CPU sec, 3.916 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (100, 286657, 80, 105)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 375, 841)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2189)
[M::mem_pestat] mean and std.dev: (494.30, 429.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2863)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 515)
[M::mem_pestat] mean and std.dev: (202.42, 92.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 643)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 534, 1537)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4323)
[M::mem_pestat] mean and std.dev: (725.08, 698.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5716)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 335, 939)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2357)
[M::mem_pestat] mean and std.dev: (521.56, 477.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3066)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723538 reads in 132.925 CPU sec, 4.191 real sec
[M::process] read 723548 sequences (100000183 bp) in 2.917 CPU sec, 2.926 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (95, 286317, 65, 98)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 444, 974)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2534)
[M::mem_pestat] mean and std.dev: (592.56, 550.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3314)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 518)
[M::mem_pestat] mean and std.dev: (202.91, 93.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 647)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 533, 1458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4038)
[M::mem_pestat] mean and std.dev: (720.53, 729.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5328)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 435, 1241)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3243)
[M::mem_pestat] mean and std.dev: (673.49, 745.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4244)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (101, 285979, 68, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (254, 531, 1243)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3221)
[M::mem_pestat] mean and std.dev: (770.16, 644.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4210)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 184, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 513)
[M::mem_pestat] mean and std.dev: (202.76, 93.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 640)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (123, 383, 929)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2541)
[M::mem_pestat] mean and std.dev: (548.35, 604.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3347)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 505, 1226)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3344)
[M::mem_pestat] mean and std.dev: (695.24, 713.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4403)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723766 reads in 360.995 CPU sec, 11.499 real sec
[M::process] read 722840 sequences (100000109 bp) in 3.143 CPU sec, 3.175 real sec...
sorting block 40, #reads = 1076619 mem = 536878992 peak = 954945536
[M::mem_process_seqs] Processed 723126 reads in 195.407 CPU sec, 6.260 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (119, 286786, 81, 102)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 463, 1088)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2888)
[M::mem_pestat] mean and std.dev: (545.51, 494.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3788)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 184, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 516)
[M::mem_pestat] mean and std.dev: (202.97, 93.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 644)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (296, 598, 1381)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3551)
[M::mem_pestat] mean and std.dev: (823.70, 813.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4636)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 548, 1216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3174)
[M::mem_pestat] mean and std.dev: (734.02, 668.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4153)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 41, #reads = 1077399 mem = 536885883 peak = 954945536
[M::process] read 722196 sequences (100000198 bp) in 3.455 CPU sec, 3.611 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (102, 286248, 81, 112)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (276, 558, 1002)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2454)
[M::mem_pestat] mean and std.dev: (622.50, 495.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3180)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 519)
[M::mem_pestat] mean and std.dev: (203.83, 93.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 648)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 655, 1018)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2634)
[M::mem_pestat] mean and std.dev: (591.23, 504.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3442)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 486, 1247)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3327)
[M::mem_pestat] mean and std.dev: (736.66, 678.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4367)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721866 sequences (100000299 bp) in 2.171 CPU sec, 2.176 real sec...
[M::mem_process_seqs] Processed 723548 reads in 228.213 CPU sec, 7.297 real sec
[M::mem_process_seqs] Processed 722840 reads in 158.799 CPU sec, 5.161 real sec
sorting block 42, #reads = 1078229 mem = 536883110 peak = 954945536
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (91, 286524, 80, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 335, 822)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2106)
[M::mem_pestat] mean and std.dev: (513.40, 469.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2748)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 186, 263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 525)
[M::mem_pestat] mean and std.dev: (205.07, 94.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 656)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (260, 512, 1576)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4208)
[M::mem_pestat] mean and std.dev: (640.43, 704.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5524)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (264, 477, 1580)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4212)
[M::mem_pestat] mean and std.dev: (867.39, 864.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5528)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725156 sequences (100000215 bp) in 3.819 CPU sec, 4.075 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (124, 285578, 79, 104)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 324, 885)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2277)
[M::mem_pestat] mean and std.dev: (472.19, 422.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2973)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 187, 265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 529)
[M::mem_pestat] mean and std.dev: (206.32, 95.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 661)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 547, 1444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3934)
[M::mem_pestat] mean and std.dev: (883.38, 974.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5179)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 509, 1254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3312)
[M::mem_pestat] mean and std.dev: (812.04, 810.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4341)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728508 sequences (100000013 bp) in 2.272 CPU sec, 2.281 real sec...
[M::mem_process_seqs] Processed 722196 reads in 228.739 CPU sec, 7.378 real sec
sorting block 43, #reads = 1076692 mem = 536884127 peak = 954945536
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (98, 286927, 58, 135)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 310, 821)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2151)
[M::mem_pestat] mean and std.dev: (476.65, 480.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2816)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 182, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 511)
[M::mem_pestat] mean and std.dev: (200.98, 92.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 638)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (131, 347, 929)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2525)
[M::mem_pestat] mean and std.dev: (569.38, 611.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3323)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 494, 1092)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2796)
[M::mem_pestat] mean and std.dev: (716.22, 677.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3648)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727902 sequences (100000037 bp) in 2.938 CPU sec, 2.942 real sec...
[M::mem_process_seqs] Processed 725156 reads in 135.115 CPU sec, 4.442 real sec
[M::mem_process_seqs] Processed 721866 reads in 359.850 CPU sec, 11.634 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (92, 288209, 65, 86)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 429, 1321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3515)
[M::mem_pestat] mean and std.dev: (709.22, 717.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4612)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 177, 250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 494)
[M::mem_pestat] mean and std.dev: (195.55, 89.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 616)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 767, 1414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3806)
[M::mem_pestat] mean and std.dev: (917.52, 897.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5002)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 569, 1169)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3085)
[M::mem_pestat] mean and std.dev: (687.19, 591.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4043)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 44, #reads = 1077302 mem = 536878790 peak = 954945536
[M::process] read 727470 sequences (100000229 bp) in 3.531 CPU sec, 3.776 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (99, 288185, 66, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 466, 1361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3685)
[M::mem_pestat] mean and std.dev: (789.27, 828.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4847)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 178, 251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 495)
[M::mem_pestat] mean and std.dev: (196.48, 89.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 617)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 525, 1233)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3219)
[M::mem_pestat] mean and std.dev: (722.75, 715.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4212)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 457, 999)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2547)
[M::mem_pestat] mean and std.dev: (537.19, 456.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3321)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 728508 reads in 254.470 CPU sec, 8.136 real sec
[M::mem_process_seqs] Processed 727902 reads in 162.136 CPU sec, 5.151 real sec
sorting block 45, #reads = 1078922 mem = 536878867 peak = 954945536
[M::process] read 727158 sequences (100000229 bp) in 3.670 CPU sec, 3.909 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (89, 287804, 69, 121)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 387, 1094)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2952)
[M::mem_pestat] mean and std.dev: (563.77, 567.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3881)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 501)
[M::mem_pestat] mean and std.dev: (197.84, 90.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 625)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (337, 805, 1691)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4399)
[M::mem_pestat] mean and std.dev: (1112.81, 1000.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5753)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (284, 619, 1328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3416)
[M::mem_pestat] mean and std.dev: (804.08, 677.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4460)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726580 sequences (100000053 bp) in 3.973 CPU sec, 4.226 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (93, 288281, 61, 123)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 450, 968)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2446)
[M::mem_pestat] mean and std.dev: (619.00, 555.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3185)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 501)
[M::mem_pestat] mean and std.dev: (198.03, 91.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 625)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (282, 927, 1837)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4947)
[M::mem_pestat] mean and std.dev: (966.80, 838.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6502)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (284, 508, 1317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3383)
[M::mem_pestat] mean and std.dev: (778.20, 744.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4416)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 727470 reads in 228.493 CPU sec, 7.308 real sec
sorting block 46, #reads = 1080937 mem = 536877884 peak = 954945536
[M::mem_process_seqs] Processed 727158 reads in 161.034 CPU sec, 5.106 real sec
[M::process] read 726162 sequences (100000008 bp) in 3.538 CPU sec, 3.713 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (100, 287906, 63, 91)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 314, 716)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1774)
[M::mem_pestat] mean and std.dev: (426.92, 345.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2303)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 508)
[M::mem_pestat] mean and std.dev: (199.58, 92.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 634)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 443, 916)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2476)
[M::mem_pestat] mean and std.dev: (480.39, 416.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3256)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 538, 1025)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2569)
[M::mem_pestat] mean and std.dev: (580.80, 473.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3341)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 47, #reads = 1081280 mem = 536877343 peak = 954945536
[M::process] read 725726 sequences (100000163 bp) in 3.830 CPU sec, 4.112 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (97, 287598, 62, 89)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 413, 902)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2320)
[M::mem_pestat] mean and std.dev: (572.05, 512.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3029)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 511)
[M::mem_pestat] mean and std.dev: (200.20, 92.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 638)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 651, 1635)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4497)
[M::mem_pestat] mean and std.dev: (899.98, 872.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5928)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 407, 628)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1384)
[M::mem_pestat] mean and std.dev: (437.93, 264.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1762)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 726580 reads in 226.007 CPU sec, 7.232 real sec
[M::mem_process_seqs] Processed 726162 reads in 160.476 CPU sec, 5.081 real sec
[M::process] read 725882 sequences (100000050 bp) in 3.294 CPU sec, 3.478 real sec...
sorting block 48, #reads = 1080680 mem = 536879531 peak = 954945536
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (91, 287743, 68, 102)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 338, 881)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2287)
[M::mem_pestat] mean and std.dev: (430.75, 374.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2990)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 508)
[M::mem_pestat] mean and std.dev: (200.16, 92.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 634)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 554, 1202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3178)
[M::mem_pestat] mean and std.dev: (701.25, 689.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4166)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 328, 835)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2067)
[M::mem_pestat] mean and std.dev: (522.45, 468.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2683)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724674 sequences (100000246 bp) in 3.689 CPU sec, 3.919 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (92, 287763, 60, 89)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 552, 1092)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2886)
[M::mem_pestat] mean and std.dev: (642.12, 602.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3783)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 508)
[M::mem_pestat] mean and std.dev: (200.26, 92.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 634)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (246, 653, 1063)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2697)
[M::mem_pestat] mean and std.dev: (645.07, 553.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3514)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 440, 933)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2379)
[M::mem_pestat] mean and std.dev: (535.59, 447.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3102)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 725726 reads in 224.671 CPU sec, 7.189 real sec
[M::process] read 724630 sequences (100000005 bp) in 2.452 CPU sec, 2.518 real sec...
[M::mem_process_seqs] Processed 725882 reads in 160.496 CPU sec, 5.207 real sec
sorting block 49, #reads = 1080086 mem = 536877947 peak = 954945536
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (114, 286876, 79, 101)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 451, 1027)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2647)
[M::mem_pestat] mean and std.dev: (612.36, 578.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3457)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 512)
[M::mem_pestat] mean and std.dev: (201.76, 93.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 639)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 793, 2213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6159)
[M::mem_pestat] mean and std.dev: (1428.67, 1500.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8132)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (277, 632, 1161)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2929)
[M::mem_pestat] mean and std.dev: (730.21, 623.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3813)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723854 sequences (100000168 bp) in 3.109 CPU sec, 3.329 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (91, 287296, 63, 81)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 344, 883)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2285)
[M::mem_pestat] mean and std.dev: (541.73, 485.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2986)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 182, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 512)
[M::mem_pestat] mean and std.dev: (201.40, 92.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 639)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 825, 1843)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5071)
[M::mem_pestat] mean and std.dev: (1103.48, 1092.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6685)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 507, 911)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2253)
[M::mem_pestat] mean and std.dev: (619.01, 478.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2924)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724674 reads in 223.168 CPU sec, 7.249 real sec
[M::process] read 724090 sequences (100000263 bp) in 2.512 CPU sec, 2.517 real sec...
sorting block 50, #reads = 1079971 mem = 536887103 peak = 954945536
[M::process] read 723876 sequences (100000095 bp) in 2.406 CPU sec, 2.412 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (118, 286896, 60, 96)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 562, 1136)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3002)
[M::mem_pestat] mean and std.dev: (760.57, 737.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3935)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 515)
[M::mem_pestat] mean and std.dev: (202.52, 93.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 643)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 626, 913)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2271)
[M::mem_pestat] mean and std.dev: (536.17, 402.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2950)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (258, 532, 1404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3696)
[M::mem_pestat] mean and std.dev: (768.89, 762.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4842)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723854 reads in 124.821 CPU sec, 4.281 real sec
sorting block 51, #reads = 1078160 mem = 536878472 peak = 1008771072
[M::mem_process_seqs] Processed 724630 reads in 346.444 CPU sec, 11.367 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 287117, 68, 92)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 413, 945)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2357)
[M::mem_pestat] mean and std.dev: (550.28, 480.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3063)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 512)
[M::mem_pestat] mean and std.dev: (201.61, 92.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 639)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 736, 1354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3620)
[M::mem_pestat] mean and std.dev: (768.81, 703.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4753)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 381, 861)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2187)
[M::mem_pestat] mean and std.dev: (494.29, 399.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2850)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 52, #reads = 1077766 mem = 536880317 peak = 1008771072
[M::process] read 724240 sequences (100000207 bp) in 3.591 CPU sec, 4.041 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (118, 286353, 60, 101)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 602, 1412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3810)
[M::mem_pestat] mean and std.dev: (753.41, 617.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5009)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 512)
[M::mem_pestat] mean and std.dev: (201.66, 92.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 639)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 613, 1377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3713)
[M::mem_pestat] mean and std.dev: (757.65, 700.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4881)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 475, 1069)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2745)
[M::mem_pestat] mean and std.dev: (638.64, 470.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3583)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724090 reads in 257.458 CPU sec, 8.287 real sec
[M::mem_process_seqs] Processed 723876 reads in 164.199 CPU sec, 5.206 real sec
[M::process] read 723856 sequences (100000228 bp) in 3.553 CPU sec, 3.740 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 286675, 75, 102)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 385, 625)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1473)
[M::mem_pestat] mean and std.dev: (394.31, 259.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1897)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 509)
[M::mem_pestat] mean and std.dev: (201.30, 92.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 635)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 600, 2378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6696)
[M::mem_pestat] mean and std.dev: (1472.61, 1718.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8855)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 333, 1109)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2933)
[M::mem_pestat] mean and std.dev: (664.91, 679.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3845)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 53, #reads = 1077732 mem = 536881897 peak = 1008771072
[M::process] read 723468 sequences (100000150 bp) in 3.388 CPU sec, 3.667 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (124, 285810, 62, 115)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (252, 341, 1072)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2712)
[M::mem_pestat] mean and std.dev: (580.41, 511.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3532)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 512)
[M::mem_pestat] mean and std.dev: (201.60, 92.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 639)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 838, 1767)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4819)
[M::mem_pestat] mean and std.dev: (886.59, 877.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6345)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 449, 987)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2485)
[M::mem_pestat] mean and std.dev: (608.78, 513.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3234)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724240 reads in 226.645 CPU sec, 7.219 real sec
[M::process] read 722904 sequences (100000060 bp) in 2.724 CPU sec, 2.770 real sec...
[M::mem_process_seqs] Processed 723856 reads in 160.747 CPU sec, 5.267 real sec
sorting block 54, #reads = 1076198 mem = 536877765 peak = 1008771072
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (94, 286326, 93, 115)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 391, 994)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2504)
[M::mem_pestat] mean and std.dev: (619.08, 614.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3259)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 184, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 513)
[M::mem_pestat] mean and std.dev: (202.51, 92.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 640)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 634, 1233)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3247)
[M::mem_pestat] mean and std.dev: (724.98, 672.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4254)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (259, 460, 933)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2281)
[M::mem_pestat] mean and std.dev: (635.62, 501.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2955)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722398 sequences (100000027 bp) in 3.307 CPU sec, 3.478 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (115, 285855, 60, 95)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 403, 939)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2375)
[M::mem_pestat] mean and std.dev: (566.98, 489.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3093)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 519)
[M::mem_pestat] mean and std.dev: (203.72, 93.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 648)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 365, 1155)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3145)
[M::mem_pestat] mean and std.dev: (618.38, 646.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4140)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 347, 915)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2361)
[M::mem_pestat] mean and std.dev: (514.37, 459.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3084)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722808 sequences (100000197 bp) in 2.395 CPU sec, 2.398 real sec...
[M::mem_process_seqs] Processed 723468 reads in 231.716 CPU sec, 7.555 real sec
sorting block 55, #reads = 1076585 mem = 536880070 peak = 1008771072
[M::mem_process_seqs] Processed 722904 reads in 159.682 CPU sec, 5.156 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (106, 286130, 69, 98)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 423, 764)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1898)
[M::mem_pestat] mean and std.dev: (497.23, 405.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2465)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 519)
[M::mem_pestat] mean and std.dev: (203.94, 93.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 648)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (260, 556, 1098)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2774)
[M::mem_pestat] mean and std.dev: (554.98, 450.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3612)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 341, 687)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1659)
[M::mem_pestat] mean and std.dev: (438.69, 347.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2145)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 56, #reads = 1075799 mem = 536880113 peak = 1008771072
[M::process] read 722148 sequences (100000024 bp) in 3.357 CPU sec, 3.582 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (113, 286542, 81, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 506, 1365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3643)
[M::mem_pestat] mean and std.dev: (734.91, 727.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4782)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 522)
[M::mem_pestat] mean and std.dev: (203.89, 93.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 652)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (297, 647, 1575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4131)
[M::mem_pestat] mean and std.dev: (846.75, 905.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5409)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 390, 1089)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2851)
[M::mem_pestat] mean and std.dev: (617.44, 644.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3732)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722226 sequences (100000167 bp) in 2.104 CPU sec, 2.109 real sec...
[M::mem_process_seqs] Processed 722398 reads in 225.766 CPU sec, 7.297 real sec
[M::mem_process_seqs] Processed 722808 reads in 158.372 CPU sec, 5.207 real sec
sorting block 57, #reads = 1077302 mem = 536878544 peak = 1008771072
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (117, 285990, 79, 110)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 377, 939)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2341)
[M::mem_pestat] mean and std.dev: (582.11, 507.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3042)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 186, 262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 520)
[M::mem_pestat] mean and std.dev: (204.81, 94.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 649)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (303, 710, 1707)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4515)
[M::mem_pestat] mean and std.dev: (845.42, 809.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5919)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 629, 1022)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2624)
[M::mem_pestat] mean and std.dev: (702.86, 572.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3425)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726258 sequences (100000272 bp) in 3.137 CPU sec, 3.250 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (105, 285919, 52, 86)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 456, 1297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3453)
[M::mem_pestat] mean and std.dev: (756.90, 773.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4531)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 186, 263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 525)
[M::mem_pestat] mean and std.dev: (205.26, 94.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 656)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (343, 725, 1452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3670)
[M::mem_pestat] mean and std.dev: (838.73, 703.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4779)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (266, 527, 1051)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2621)
[M::mem_pestat] mean and std.dev: (619.04, 478.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3406)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 732820 sequences (100000091 bp) in 2.709 CPU sec, 2.718 real sec...
[M::mem_process_seqs] Processed 722148 reads in 227.630 CPU sec, 7.388 real sec
[M::mem_process_seqs] Processed 722226 reads in 157.815 CPU sec, 5.109 real sec
sorting block 58, #reads = 1076214 mem = 536878774 peak = 1008771072
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (105, 287631, 62, 112)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 303, 1002)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2520)
[M::mem_pestat] mean and std.dev: (597.18, 613.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3279)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 505)
[M::mem_pestat] mean and std.dev: (199.27, 91.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 630)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (254, 596, 1398)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3686)
[M::mem_pestat] mean and std.dev: (816.47, 787.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4830)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 373, 1168)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3090)
[M::mem_pestat] mean and std.dev: (578.38, 619.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4051)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 731400 sequences (100000021 bp) in 3.462 CPU sec, 3.659 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 289898, 74, 87)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 340, 733)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1781)
[M::mem_pestat] mean and std.dev: (447.56, 352.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2305)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (126, 172, 239)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 465)
[M::mem_pestat] mean and std.dev: (188.26, 83.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 578)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (316, 506, 1023)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2437)
[M::mem_pestat] mean and std.dev: (621.99, 509.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3144)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 371, 807)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1967)
[M::mem_pestat] mean and std.dev: (488.90, 391.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2547)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 730302 sequences (100000001 bp) in 2.560 CPU sec, 2.558 real sec...
[M::mem_process_seqs] Processed 726258 reads in 234.152 CPU sec, 7.519 real sec
sorting block 59, #reads = 1075232 mem = 536879711 peak = 1008771072
[M::mem_process_seqs] Processed 732820 reads in 161.542 CPU sec, 5.135 real sec
sorting block 60, #reads = 1078119 mem = 536879233 peak = 1008771072
[M::process] read 729538 sequences (100000030 bp) in 3.415 CPU sec, 3.546 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (120, 289402, 49, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 404, 857)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2159)
[M::mem_pestat] mean and std.dev: (508.04, 453.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2810)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 175, 246)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 484)
[M::mem_pestat] mean and std.dev: (192.94, 87.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 603)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 439, 860)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2306)
[M::mem_pestat] mean and std.dev: (517.38, 466.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3029)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 389, 1370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3720)
[M::mem_pestat] mean and std.dev: (704.00, 724.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4895)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728744 sequences (100000063 bp) in 2.640 CPU sec, 2.648 real sec...
[M::mem_process_seqs] Processed 730302 reads in 135.962 CPU sec, 4.295 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (96, 289662, 59, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 473, 906)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2216)
[M::mem_pestat] mean and std.dev: (582.78, 450.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2871)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (126, 174, 242)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 474)
[M::mem_pestat] mean and std.dev: (190.54, 85.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 590)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 400, 721)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1783)
[M::mem_pestat] mean and std.dev: (434.87, 356.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2314)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 308, 487)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1065)
[M::mem_pestat] mean and std.dev: (301.51, 185.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1354)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (109, 289361, 80, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (293, 640, 1262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3200)
[M::mem_pestat] mean and std.dev: (725.63, 638.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4169)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 176, 248)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 488)
[M::mem_pestat] mean and std.dev: (194.41, 88.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 608)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 591, 1468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3904)
[M::mem_pestat] mean and std.dev: (812.84, 827.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5122)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 395, 1158)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3074)
[M::mem_pestat] mean and std.dev: (645.37, 590.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4032)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 731400 reads in 355.475 CPU sec, 11.304 real sec
[M::process] read 728234 sequences (100000039 bp) in 2.588 CPU sec, 2.595 real sec...
sorting block 61, #reads = 1081708 mem = 536878113 peak = 1008771072
[M::mem_process_seqs] Processed 729538 reads in 191.124 CPU sec, 6.098 real sec
sorting block 62, #reads = 1081007 mem = 536882658 peak = 1008771072
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 288268, 80, 88)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 478, 920)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2302)
[M::mem_pestat] mean and std.dev: (562.91, 423.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2993)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 177, 249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 491)
[M::mem_pestat] mean and std.dev: (195.31, 89.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 612)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 569, 1961)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5511)
[M::mem_pestat] mean and std.dev: (995.53, 1046.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7286)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 519, 1099)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2851)
[M::mem_pestat] mean and std.dev: (647.25, 561.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3727)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727724 sequences (100000234 bp) in 3.666 CPU sec, 3.878 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (88, 288389, 82, 93)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 413, 713)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1727)
[M::mem_pestat] mean and std.dev: (449.23, 352.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2234)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 178, 250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 494)
[M::mem_pestat] mean and std.dev: (196.00, 89.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 616)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (262, 452, 1100)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2776)
[M::mem_pestat] mean and std.dev: (581.43, 536.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3614)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 540, 1015)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2533)
[M::mem_pestat] mean and std.dev: (614.83, 458.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3292)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727554 sequences (100000151 bp) in 2.570 CPU sec, 2.568 real sec...
[M::mem_process_seqs] Processed 728744 reads in 247.796 CPU sec, 7.891 real sec
[M::mem_process_seqs] Processed 728234 reads in 163.222 CPU sec, 5.196 real sec
sorting block 63, #reads = 1077487 mem = 536882755 peak = 1008771072
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (106, 288610, 65, 91)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 378, 1061)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2793)
[M::mem_pestat] mean and std.dev: (604.27, 598.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3659)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 178, 252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 498)
[M::mem_pestat] mean and std.dev: (197.05, 90.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 621)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (436, 712, 1696)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4216)
[M::mem_pestat] mean and std.dev: (901.34, 818.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5476)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 491, 1029)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2677)
[M::mem_pestat] mean and std.dev: (634.64, 595.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3501)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727406 sequences (100000194 bp) in 3.398 CPU sec, 3.650 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (87, 288073, 71, 103)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (308, 684, 1646)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4322)
[M::mem_pestat] mean and std.dev: (848.45, 683.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5660)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 178, 252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 498)
[M::mem_pestat] mean and std.dev: (197.27, 90.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 621)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 367, 883)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2323)
[M::mem_pestat] mean and std.dev: (513.99, 514.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3043)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 461, 1021)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2621)
[M::mem_pestat] mean and std.dev: (582.78, 492.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3421)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726284 sequences (100000123 bp) in 2.020 CPU sec, 2.025 real sec...
[M::mem_process_seqs] Processed 727724 reads in 233.355 CPU sec, 7.464 real sec
[M::mem_process_seqs] Processed 727554 reads in 159.960 CPU sec, 5.201 real sec
sorting block 64, #reads = 1080111 mem = 536879628 peak = 1008771072
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (89, 287617, 73, 91)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 371, 1027)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2693)
[M::mem_pestat] mean and std.dev: (508.36, 516.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3526)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 501)
[M::mem_pestat] mean and std.dev: (197.93, 91.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 625)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 347, 871)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2213)
[M::mem_pestat] mean and std.dev: (481.24, 396.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2884)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (281, 616, 1361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3521)
[M::mem_pestat] mean and std.dev: (787.00, 753.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4601)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725758 sequences (100000065 bp) in 3.706 CPU sec, 3.883 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (113, 287369, 62, 111)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 364, 1376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3684)
[M::mem_pestat] mean and std.dev: (708.48, 814.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4838)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 180, 255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 505)
[M::mem_pestat] mean and std.dev: (199.12, 91.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 630)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 747, 1787)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4939)
[M::mem_pestat] mean and std.dev: (1138.43, 1278.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6515)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 458, 1333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3497)
[M::mem_pestat] mean and std.dev: (757.27, 804.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4579)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 727406 reads in 228.866 CPU sec, 7.371 real sec
[M::process] read 725720 sequences (100000223 bp) in 2.660 CPU sec, 2.660 real sec...
sorting block 65, #reads = 1079985 mem = 536879356 peak = 1008771072
[M::mem_process_seqs] Processed 726284 reads in 159.856 CPU sec, 5.179 real sec
sorting block 66, #reads = 1077230 mem = 536880188 peak = 1008771072
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (138, 286988, 65, 103)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 384, 792)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1922)
[M::mem_pestat] mean and std.dev: (482.46, 365.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2487)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 505)
[M::mem_pestat] mean and std.dev: (199.62, 91.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 630)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 666, 1717)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4721)
[M::mem_pestat] mean and std.dev: (873.05, 987.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6223)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 577, 1285)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3389)
[M::mem_pestat] mean and std.dev: (741.79, 631.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4441)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725552 sequences (100000230 bp) in 3.895 CPU sec, 4.115 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (88, 286718, 83, 109)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 348, 907)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2331)
[M::mem_pestat] mean and std.dev: (498.79, 467.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3043)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 180, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 508)
[M::mem_pestat] mean and std.dev: (199.95, 92.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 634)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 612, 1621)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4503)
[M::mem_pestat] mean and std.dev: (997.48, 1019.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5944)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 513, 1335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3511)
[M::mem_pestat] mean and std.dev: (749.89, 732.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4599)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725720 sequences (100000097 bp) in 2.710 CPU sec, 2.702 real sec...
[M::mem_process_seqs] Processed 725758 reads in 237.740 CPU sec, 7.647 real sec
[M::mem_process_seqs] Processed 725720 reads in 162.289 CPU sec, 5.281 real sec
sorting block 67, #reads = 1075838 mem = 536879851 peak = 1008771072
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (110, 287693, 67, 128)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 464, 1046)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2708)
[M::mem_pestat] mean and std.dev: (678.16, 643.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3539)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 505)
[M::mem_pestat] mean and std.dev: (199.51, 91.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 630)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 480, 1171)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3163)
[M::mem_pestat] mean and std.dev: (694.94, 712.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4159)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 308, 758)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1806)
[M::mem_pestat] mean and std.dev: (468.01, 403.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2330)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725476 sequences (100000231 bp) in 3.584 CPU sec, 3.745 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (95, 286649, 65, 81)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 485, 1162)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3026)
[M::mem_pestat] mean and std.dev: (635.71, 565.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3958)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 505)
[M::mem_pestat] mean and std.dev: (199.61, 91.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 630)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (130, 442, 1372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3856)
[M::mem_pestat] mean and std.dev: (776.58, 864.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5098)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (272, 466, 979)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2393)
[M::mem_pestat] mean and std.dev: (612.36, 517.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3100)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724968 sequences (100000191 bp) in 2.660 CPU sec, 2.661 real sec...
[M::mem_process_seqs] Processed 725552 reads in 235.518 CPU sec, 7.618 real sec
sorting block 68, #reads = 1075644 mem = 536881470 peak = 1008771072
[M::mem_process_seqs] Processed 725720 reads in 161.930 CPU sec, 5.283 real sec
sorting block 69, #reads = 1075617 mem = 536878153 peak = 1008771072
[M::process] read 724670 sequences (100000286 bp) in 3.321 CPU sec, 3.511 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (97, 286473, 65, 96)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 377, 1020)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2648)
[M::mem_pestat] mean and std.dev: (611.07, 602.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3462)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 182, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 512)
[M::mem_pestat] mean and std.dev: (201.42, 92.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 639)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 407, 1079)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2795)
[M::mem_pestat] mean and std.dev: (581.15, 516.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3653)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (368, 626, 1479)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3701)
[M::mem_pestat] mean and std.dev: (874.66, 776.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4812)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724136 sequences (100000225 bp) in 2.400 CPU sec, 2.403 real sec...
[M::mem_process_seqs] Processed 724968 reads in 139.266 CPU sec, 4.402 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (90, 286937, 76, 106)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 368, 816)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2010)
[M::mem_pestat] mean and std.dev: (482.01, 360.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2607)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 508)
[M::mem_pestat] mean and std.dev: (199.99, 92.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 634)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 684, 1165)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2967)
[M::mem_pestat] mean and std.dev: (685.54, 632.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3868)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 413, 951)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2407)
[M::mem_pestat] mean and std.dev: (558.86, 517.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3135)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (103, 286625, 72, 123)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (282, 556, 1260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3216)
[M::mem_pestat] mean and std.dev: (657.80, 551.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4194)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 512)
[M::mem_pestat] mean and std.dev: (201.43, 92.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 639)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 506, 1493)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4037)
[M::mem_pestat] mean and std.dev: (778.74, 725.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5309)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 319, 896)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2240)
[M::mem_pestat] mean and std.dev: (490.25, 423.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2912)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724516 sequences (100000206 bp) in 2.644 CPU sec, 2.646 real sec...
[M::mem_process_seqs] Processed 725476 reads in 371.282 CPU sec, 11.949 real sec
sorting block 70, #reads = 1073825 mem = 536879406 peak = 1008771072
[M::mem_process_seqs] Processed 724670 reads in 197.973 CPU sec, 6.375 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (105, 286838, 86, 105)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 377, 704)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1716)
[M::mem_pestat] mean and std.dev: (452.45, 329.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2222)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 512)
[M::mem_pestat] mean and std.dev: (201.52, 92.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 639)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 346, 870)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2270)
[M::mem_pestat] mean and std.dev: (497.67, 471.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2970)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 328, 920)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2316)
[M::mem_pestat] mean and std.dev: (527.72, 467.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3014)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 71, #reads = 1076038 mem = 536878344 peak = 1010737152
[M::process] read 725172 sequences (100000040 bp) in 3.387 CPU sec, 3.562 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (86, 286341, 66, 91)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 477, 1611)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4291)
[M::mem_pestat] mean and std.dev: (871.01, 977.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5631)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 182, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 509)
[M::mem_pestat] mean and std.dev: (201.08, 92.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 635)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 399, 859)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2199)
[M::mem_pestat] mean and std.dev: (517.89, 442.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2869)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 344, 1035)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2671)
[M::mem_pestat] mean and std.dev: (587.38, 551.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3489)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726064 sequences (100000044 bp) in 2.710 CPU sec, 2.708 real sec...
[M::mem_process_seqs] Processed 724136 reads in 243.451 CPU sec, 7.778 real sec
[M::mem_process_seqs] Processed 724516 reads in 168.828 CPU sec, 5.524 real sec
sorting block 72, #reads = 1074420 mem = 536881694 peak = 1010737152
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (101, 286778, 80, 109)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 482, 1096)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2854)
[M::mem_pestat] mean and std.dev: (636.14, 602.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3733)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 182, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 511)
[M::mem_pestat] mean and std.dev: (200.82, 92.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 638)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 693, 1315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3541)
[M::mem_pestat] mean and std.dev: (753.07, 691.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4654)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 432, 999)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2585)
[M::mem_pestat] mean and std.dev: (612.38, 529.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3378)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 734908 sequences (100000076 bp) in 3.194 CPU sec, 3.361 real sec...
[M::process] read 732026 sequences (100000059 bp) in 2.706 CPU sec, 2.718 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (85, 287000, 70, 125)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (289, 556, 1566)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4120)
[M::mem_pestat] mean and std.dev: (870.94, 838.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5397)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 505)
[M::mem_pestat] mean and std.dev: (199.38, 91.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 630)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (122, 415, 992)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2732)
[M::mem_pestat] mean and std.dev: (559.46, 559.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3602)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 374, 984)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2528)
[M::mem_pestat] mean and std.dev: (612.67, 588.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3300)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 725172 reads in 237.135 CPU sec, 7.667 real sec
[M::mem_process_seqs] Processed 726064 reads in 167.013 CPU sec, 5.337 real sec
sorting block 73, #reads = 1074142 mem = 536890731 peak = 1010737152
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (98, 290131, 50, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 475, 1104)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2922)
[M::mem_pestat] mean and std.dev: (678.28, 583.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3831)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (125, 170, 236)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 458)
[M::mem_pestat] mean and std.dev: (185.78, 81.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 569)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (267, 1007, 2494)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6948)
[M::mem_pestat] mean and std.dev: (1279.53, 1490.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9175)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 543, 1129)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2967)
[M::mem_pestat] mean and std.dev: (735.46, 679.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3886)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 731074 sequences (100000001 bp) in 3.330 CPU sec, 3.536 real sec...
[M::process] read 730902 sequences (100000196 bp) in 2.106 CPU sec, 2.114 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (91, 289741, 52, 94)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 337, 856)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2200)
[M::mem_pestat] mean and std.dev: (475.13, 458.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2872)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (126, 173, 242)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 474)
[M::mem_pestat] mean and std.dev: (190.29, 85.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 590)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (259, 773, 2023)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5551)
[M::mem_pestat] mean and std.dev: (1051.86, 907.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7315)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 354, 976)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2478)
[M::mem_pestat] mean and std.dev: (534.75, 470.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3229)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 734908 reads in 245.289 CPU sec, 7.842 real sec
sorting block 74, #reads = 1074155 mem = 536879334 peak = 1010737152
[M::mem_process_seqs] Processed 732026 reads in 169.457 CPU sec, 5.566 real sec
sorting block 75, #reads = 1078475 mem = 536878180 peak = 1010737152
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 289460, 61, 94)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 439, 1377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3697)
[M::mem_pestat] mean and std.dev: (767.04, 785.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4857)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 175, 245)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 481)
[M::mem_pestat] mean and std.dev: (192.19, 86.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 599)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (124, 542, 1091)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3025)
[M::mem_pestat] mean and std.dev: (657.74, 704.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3992)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 437, 926)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2320)
[M::mem_pestat] mean and std.dev: (553.81, 447.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3017)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 731020 sequences (100000104 bp) in 2.955 CPU sec, 3.100 real sec...
[M::process] read 730284 sequences (100000106 bp) in 2.829 CPU sec, 2.840 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (87, 289045, 72, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 400, 1147)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3013)
[M::mem_pestat] mean and std.dev: (595.10, 506.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3946)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 175, 245)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 481)
[M::mem_pestat] mean and std.dev: (192.32, 86.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 599)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 408, 906)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2308)
[M::mem_pestat] mean and std.dev: (469.59, 432.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3009)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 514, 1150)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3024)
[M::mem_pestat] mean and std.dev: (669.35, 519.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3961)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 731074 reads in 239.170 CPU sec, 7.740 real sec
[M::mem_process_seqs] Processed 730902 reads in 161.671 CPU sec, 5.151 real sec
sorting block 76, #reads = 1079781 mem = 536882467 peak = 1010737152
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (101, 289517, 72, 97)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 341, 813)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2071)
[M::mem_pestat] mean and std.dev: (441.24, 408.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2700)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 175, 245)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 481)
[M::mem_pestat] mean and std.dev: (192.24, 86.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 599)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (246, 600, 1228)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3192)
[M::mem_pestat] mean and std.dev: (712.66, 657.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4174)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 483, 1136)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2976)
[M::mem_pestat] mean and std.dev: (753.54, 707.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3896)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728930 sequences (100000014 bp) in 3.576 CPU sec, 3.726 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (86, 289393, 49, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 302, 687)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1711)
[M::mem_pestat] mean and std.dev: (396.42, 319.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2223)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 175, 246)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 484)
[M::mem_pestat] mean and std.dev: (193.17, 87.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 603)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 771, 2512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7140)
[M::mem_pestat] mean and std.dev: (1281.85, 1365.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9454)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (269, 537, 1211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3095)
[M::mem_pestat] mean and std.dev: (705.83, 673.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4037)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728828 sequences (100000264 bp) in 2.260 CPU sec, 2.258 real sec...
[M::mem_process_seqs] Processed 731020 reads in 219.922 CPU sec, 7.122 real sec
sorting block 77, #reads = 1078712 mem = 536885484 peak = 1010737152
[M::mem_process_seqs] Processed 730284 reads in 146.826 CPU sec, 4.762 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (103, 288707, 64, 90)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 370, 788)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1960)
[M::mem_pestat] mean and std.dev: (416.54, 364.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2546)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 177, 249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 491)
[M::mem_pestat] mean and std.dev: (195.34, 89.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 612)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 586, 1067)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2823)
[M::mem_pestat] mean and std.dev: (580.57, 453.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3701)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 322, 643)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1511)
[M::mem_pestat] mean and std.dev: (361.28, 241.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1945)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728662 sequences (100000157 bp) in 3.854 CPU sec, 4.076 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (97, 288854, 61, 86)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 417, 778)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1858)
[M::mem_pestat] mean and std.dev: (469.07, 371.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2398)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 177, 250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 494)
[M::mem_pestat] mean and std.dev: (195.83, 89.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 616)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 390, 992)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2516)
[M::mem_pestat] mean and std.dev: (536.61, 546.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3278)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 615, 1040)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2722)
[M::mem_pestat] mean and std.dev: (647.42, 604.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3563)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727804 sequences (100000061 bp) in 2.750 CPU sec, 2.757 real sec...
[M::mem_process_seqs] Processed 728930 reads in 232.307 CPU sec, 7.446 real sec
sorting block 78, #reads = 1077649 mem = 536883223 peak = 1010737152
[M::process] read 727370 sequences (100000278 bp) in 2.613 CPU sec, 2.615 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (98, 288442, 46, 107)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 318, 574)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1316)
[M::mem_pestat] mean and std.dev: (391.18, 265.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1687)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 178, 251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 497)
[M::mem_pestat] mean and std.dev: (196.43, 90.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 620)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 461, 1522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4202)
[M::mem_pestat] mean and std.dev: (813.64, 853.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5542)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 485, 1216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3176)
[M::mem_pestat] mean and std.dev: (720.03, 646.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4156)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 728662 reads in 127.237 CPU sec, 4.195 real sec
sorting block 79, #reads = 1078813 mem = 536879968 peak = 1010737152
[M::mem_process_seqs] Processed 728828 reads in 340.269 CPU sec, 11.003 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (86, 288115, 67, 88)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 446, 952)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2402)
[M::mem_pestat] mean and std.dev: (543.71, 424.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3127)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 178, 252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 498)
[M::mem_pestat] mean and std.dev: (196.99, 90.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 621)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (276, 612, 1127)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2829)
[M::mem_pestat] mean and std.dev: (716.21, 640.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3680)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 641, 1271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3371)
[M::mem_pestat] mean and std.dev: (805.63, 792.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4421)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726420 sequences (100000083 bp) in 4.223 CPU sec, 4.679 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 287932, 67, 96)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 509, 1380)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3710)
[M::mem_pestat] mean and std.dev: (772.33, 731.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4875)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 501)
[M::mem_pestat] mean and std.dev: (198.05, 91.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 625)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (348, 668, 1490)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3774)
[M::mem_pestat] mean and std.dev: (975.44, 917.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4916)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (285, 555, 1152)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2886)
[M::mem_pestat] mean and std.dev: (663.18, 472.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3753)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 727804 reads in 267.633 CPU sec, 8.577 real sec
sorting block 80, #reads = 1077732 mem = 536882965 peak = 1010737152
[M::mem_process_seqs] Processed 727370 reads in 170.736 CPU sec, 5.406 real sec
[M::process] read 726442 sequences (100000172 bp) in 3.747 CPU sec, 3.959 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (109, 287639, 50, 92)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 386, 1207)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3237)
[M::mem_pestat] mean and std.dev: (720.38, 796.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4252)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 180, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 504)
[M::mem_pestat] mean and std.dev: (198.65, 91.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 629)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (255, 680, 1435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3795)
[M::mem_pestat] mean and std.dev: (1028.51, 1048.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5222)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 529, 1226)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3220)
[M::mem_pestat] mean and std.dev: (735.71, 692.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4217)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 81, #reads = 1076180 mem = 536877155 peak = 1010737152
[M::process] read 726228 sequences (100000084 bp) in 3.791 CPU sec, 4.074 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (92, 287199, 79, 84)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 578, 1041)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2705)
[M::mem_pestat] mean and std.dev: (548.56, 427.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3537)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 180, 253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 501)
[M::mem_pestat] mean and std.dev: (198.23, 90.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 625)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (288, 803, 1373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3543)
[M::mem_pestat] mean and std.dev: (763.51, 652.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4628)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 393, 1040)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2686)
[M::mem_pestat] mean and std.dev: (619.46, 629.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3509)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 726420 reads in 233.650 CPU sec, 7.472 real sec
[M::mem_process_seqs] Processed 726442 reads in 164.326 CPU sec, 5.211 real sec
[M::process] read 725340 sequences (100000083 bp) in 3.308 CPU sec, 3.457 real sec...
sorting block 82, #reads = 1076733 mem = 536879638 peak = 1010737152
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (93, 287159, 68, 118)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 376, 787)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1943)
[M::mem_pestat] mean and std.dev: (475.55, 374.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2521)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 180, 255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 505)
[M::mem_pestat] mean and std.dev: (199.04, 91.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 630)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (358, 675, 1011)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2317)
[M::mem_pestat] mean and std.dev: (641.79, 408.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2970)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 348, 835)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2089)
[M::mem_pestat] mean and std.dev: (529.61, 462.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2716)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725968 sequences (100000036 bp) in 3.932 CPU sec, 4.151 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (109, 287217, 69, 116)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 399, 1183)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3165)
[M::mem_pestat] mean and std.dev: (735.76, 760.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4156)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 182, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 508)
[M::mem_pestat] mean and std.dev: (200.24, 92.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 634)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 522, 1116)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2982)
[M::mem_pestat] mean and std.dev: (662.97, 649.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3915)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 451, 1066)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2772)
[M::mem_pestat] mean and std.dev: (578.00, 538.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3625)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 726228 reads in 233.346 CPU sec, 7.469 real sec
[M::mem_process_seqs] Processed 725340 reads in 167.290 CPU sec, 5.298 real sec
sorting block 83, #reads = 1075632 mem = 536877567 peak = 1010737152
[M::process] read 725566 sequences (100000177 bp) in 3.028 CPU sec, 3.111 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (93, 287272, 60, 91)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (255, 486, 944)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2322)
[M::mem_pestat] mean and std.dev: (648.12, 525.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3011)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 180, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 502)
[M::mem_pestat] mean and std.dev: (198.81, 91.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 626)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 536, 1120)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3078)
[M::mem_pestat] mean and std.dev: (556.87, 557.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4057)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 501, 935)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2403)
[M::mem_pestat] mean and std.dev: (535.35, 420.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3137)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 84, #reads = 1075670 mem = 536883824 peak = 1015803904
[M::process] read 725710 sequences (100000246 bp) in 3.405 CPU sec, 3.544 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (98, 287578, 74, 103)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 303, 772)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1994)
[M::mem_pestat] mean and std.dev: (477.80, 440.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2605)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 508)
[M::mem_pestat] mean and std.dev: (199.74, 91.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 634)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 681, 1498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4070)
[M::mem_pestat] mean and std.dev: (871.70, 792.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5356)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 312, 617)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1477)
[M::mem_pestat] mean and std.dev: (407.42, 326.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1907)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 725968 reads in 200.766 CPU sec, 6.381 real sec
[M::mem_process_seqs] Processed 725566 reads in 134.146 CPU sec, 4.228 real sec
[M::process] read 725152 sequences (100000130 bp) in 2.990 CPU sec, 3.059 real sec...
sorting block 85, #reads = 1075165 mem = 536879905 peak = 1015803904
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (97, 287520, 89, 106)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 371, 1139)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2981)
[M::mem_pestat] mean and std.dev: (618.65, 544.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3902)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 505)
[M::mem_pestat] mean and std.dev: (199.93, 92.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 630)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 639, 2339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6671)
[M::mem_pestat] mean and std.dev: (956.57, 1073.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8837)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 411, 1056)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2764)
[M::mem_pestat] mean and std.dev: (547.52, 483.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3618)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726408 sequences (100000110 bp) in 2.988 CPU sec, 3.071 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (96, 286654, 76, 89)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 406, 788)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1912)
[M::mem_pestat] mean and std.dev: (526.05, 421.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2474)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 508)
[M::mem_pestat] mean and std.dev: (200.11, 92.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 634)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (290, 660, 1699)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4517)
[M::mem_pestat] mean and std.dev: (1006.51, 1110.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5926)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (299, 492, 991)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2375)
[M::mem_pestat] mean and std.dev: (534.21, 393.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3067)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 732360 sequences (100000267 bp) in 2.490 CPU sec, 2.489 real sec...
[M::mem_process_seqs] Processed 725710 reads in 204.013 CPU sec, 6.477 real sec
sorting block 86, #reads = 1077440 mem = 536877811 peak = 1015803904
[M::mem_process_seqs] Processed 725152 reads in 142.887 CPU sec, 4.533 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (105, 287138, 61, 87)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 350, 1094)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2870)
[M::mem_pestat] mean and std.dev: (655.50, 641.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3758)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 180, 253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 499)
[M::mem_pestat] mean and std.dev: (198.20, 90.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 622)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (263, 568, 1271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3287)
[M::mem_pestat] mean and std.dev: (669.40, 556.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4295)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 362, 654)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1544)
[M::mem_pestat] mean and std.dev: (404.21, 294.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1989)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 731058 sequences (100000053 bp) in 3.066 CPU sec, 3.194 real sec...
[M::process] read 729230 sequences (100000214 bp) in 1.900 CPU sec, 1.901 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 288864, 73, 109)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 432, 1352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3652)
[M::mem_pestat] mean and std.dev: (711.97, 713.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4802)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (126, 173, 242)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 474)
[M::mem_pestat] mean and std.dev: (189.86, 84.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 590)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (259, 511, 1004)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2494)
[M::mem_pestat] mean and std.dev: (543.14, 470.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3239)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (350, 598, 1168)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2804)
[M::mem_pestat] mean and std.dev: (760.43, 601.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3622)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 726408 reads in 223.761 CPU sec, 7.112 real sec
sorting block 87, #reads = 1075068 mem = 536878269 peak = 1015803904
[M::mem_process_seqs] Processed 732360 reads in 154.156 CPU sec, 4.917 real sec
sorting block 88, #reads = 1068314 mem = 536887046 peak = 1064570880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (100, 288968, 76, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 302, 663)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1653)
[M::mem_pestat] mean and std.dev: (362.10, 306.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2148)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 176, 248)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 488)
[M::mem_pestat] mean and std.dev: (194.31, 87.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 608)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (299, 564, 1482)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3848)
[M::mem_pestat] mean and std.dev: (911.01, 888.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5031)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 468, 1295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3433)
[M::mem_pestat] mean and std.dev: (738.53, 685.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4502)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 729238 sequences (100000237 bp) in 3.619 CPU sec, 3.771 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (104, 289284, 71, 103)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 417, 1330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3586)
[M::mem_pestat] mean and std.dev: (668.30, 682.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4714)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 175, 244)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 478)
[M::mem_pestat] mean and std.dev: (191.88, 86.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 595)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 450, 1373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3661)
[M::mem_pestat] mean and std.dev: (737.34, 791.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4805)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 349, 738)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1780)
[M::mem_pestat] mean and std.dev: (464.21, 352.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2301)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 729230 reads in 193.348 CPU sec, 6.099 real sec
[M::process] read 729204 sequences (100000089 bp) in 2.670 CPU sec, 2.667 real sec...
[M::mem_process_seqs] Processed 731058 reads in 220.232 CPU sec, 7.229 real sec
sorting block 89, #reads = 1081511 mem = 536879231 peak = 1064570880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (90, 288444, 63, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 385, 909)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2309)
[M::mem_pestat] mean and std.dev: (620.44, 596.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3009)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 177, 249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 491)
[M::mem_pestat] mean and std.dev: (194.91, 88.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 612)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (382, 730, 1622)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4102)
[M::mem_pestat] mean and std.dev: (927.05, 827.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5342)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 378, 906)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2316)
[M::mem_pestat] mean and std.dev: (512.74, 375.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3021)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727870 sequences (100000299 bp) in 3.255 CPU sec, 3.411 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 288862, 53, 89)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 443, 1077)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2845)
[M::mem_pestat] mean and std.dev: (639.72, 639.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3729)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 176, 248)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 488)
[M::mem_pestat] mean and std.dev: (194.52, 88.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 608)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (355, 899, 1542)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3916)
[M::mem_pestat] mean and std.dev: (894.48, 627.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5103)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 514, 861)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2105)
[M::mem_pestat] mean and std.dev: (547.23, 384.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2727)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728310 sequences (100000175 bp) in 1.970 CPU sec, 1.978 real sec...
[M::mem_process_seqs] Processed 729238 reads in 196.013 CPU sec, 6.459 real sec
sorting block 90, #reads = 1080925 mem = 536879381 peak = 1064570880
[M::mem_process_seqs] Processed 729204 reads in 135.112 CPU sec, 4.402 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (103, 288430, 71, 94)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 299, 606)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1474)
[M::mem_pestat] mean and std.dev: (376.27, 310.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1908)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 178, 251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 495)
[M::mem_pestat] mean and std.dev: (196.57, 89.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 617)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 243, 837)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2181)
[M::mem_pestat] mean and std.dev: (464.74, 485.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2853)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 433, 1141)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3023)
[M::mem_pestat] mean and std.dev: (749.11, 740.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3964)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728278 sequences (100000122 bp) in 3.292 CPU sec, 3.437 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (98, 288588, 78, 102)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 301, 604)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1466)
[M::mem_pestat] mean and std.dev: (370.07, 282.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1897)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 178, 250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 494)
[M::mem_pestat] mean and std.dev: (195.75, 89.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 616)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (246, 643, 1881)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5151)
[M::mem_pestat] mean and std.dev: (901.03, 891.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6786)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 401, 696)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1642)
[M::mem_pestat] mean and std.dev: (448.61, 333.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2115)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 727870 reads in 188.798 CPU sec, 6.084 real sec
sorting block 91, #reads = 1079487 mem = 536880206 peak = 1064570880
[M::process] read 728078 sequences (100000239 bp) in 2.775 CPU sec, 2.794 real sec...
[M::mem_process_seqs] Processed 728310 reads in 134.371 CPU sec, 4.446 real sec
sorting block 92, #reads = 1081420 mem = 536878582 peak = 1099481088
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (93, 289320, 51, 85)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 364, 1056)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2696)
[M::mem_pestat] mean and std.dev: (567.40, 489.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3516)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 178, 250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 494)
[M::mem_pestat] mean and std.dev: (196.25, 90.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 616)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (107, 293, 715)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1931)
[M::mem_pestat] mean and std.dev: (359.67, 330.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2539)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 341, 977)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2457)
[M::mem_pestat] mean and std.dev: (606.45, 558.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3197)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728086 sequences (100000221 bp) in 3.452 CPU sec, 3.593 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (90, 288734, 56, 113)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 401, 1192)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3174)
[M::mem_pestat] mean and std.dev: (600.06, 566.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4165)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 178, 251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 495)
[M::mem_pestat] mean and std.dev: (196.81, 90.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 617)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (462, 726, 1670)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4086)
[M::mem_pestat] mean and std.dev: (932.83, 780.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5294)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 453, 1228)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3182)
[M::mem_pestat] mean and std.dev: (701.03, 658.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4159)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727676 sequences (100000000 bp) in 2.570 CPU sec, 2.568 real sec...
[M::mem_process_seqs] Processed 728278 reads in 221.315 CPU sec, 7.207 real sec
[M::mem_process_seqs] Processed 728078 reads in 148.098 CPU sec, 4.710 real sec
sorting block 93, #reads = 1077860 mem = 536880055 peak = 1099481088
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (91, 288884, 77, 110)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 303, 1053)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2817)
[M::mem_pestat] mean and std.dev: (587.36, 545.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3699)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 178, 251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 495)
[M::mem_pestat] mean and std.dev: (196.68, 90.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 617)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 567, 2091)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5819)
[M::mem_pestat] mean and std.dev: (1001.67, 1144.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7683)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 441, 1020)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2550)
[M::mem_pestat] mean and std.dev: (619.83, 530.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3315)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726042 sequences (100000226 bp) in 3.367 CPU sec, 3.512 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (103, 288075, 69, 113)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 474, 1082)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2862)
[M::mem_pestat] mean and std.dev: (678.66, 680.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3752)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 504)
[M::mem_pestat] mean and std.dev: (198.25, 91.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 629)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 408, 986)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2564)
[M::mem_pestat] mean and std.dev: (511.02, 468.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3353)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 405, 1529)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4121)
[M::mem_pestat] mean and std.dev: (884.06, 854.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5417)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725826 sequences (100000007 bp) in 2.269 CPU sec, 2.271 real sec...
[M::mem_process_seqs] Processed 728086 reads in 197.855 CPU sec, 6.300 real sec
sorting block 94, #reads = 1077692 mem = 536877323 peak = 1099481088
[M::mem_process_seqs] Processed 727676 reads in 135.889 CPU sec, 4.411 real sec
sorting block 95, #reads = 1079276 mem = 536880437 peak = 1099481088
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (115, 287390, 83, 89)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 393, 655)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1575)
[M::mem_pestat] mean and std.dev: (392.00, 282.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2035)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 505)
[M::mem_pestat] mean and std.dev: (199.56, 92.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 630)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 620, 1194)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3236)
[M::mem_pestat] mean and std.dev: (720.27, 693.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4257)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 546, 1224)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3182)
[M::mem_pestat] mean and std.dev: (669.88, 556.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4161)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725408 sequences (100000148 bp) in 3.222 CPU sec, 3.373 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (96, 287061, 67, 94)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 526, 1177)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3147)
[M::mem_pestat] mean and std.dev: (665.07, 559.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4132)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 508)
[M::mem_pestat] mean and std.dev: (200.15, 92.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 634)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (90, 349, 1103)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3129)
[M::mem_pestat] mean and std.dev: (564.08, 667.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4142)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 383, 730)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1688)
[M::mem_pestat] mean and std.dev: (439.05, 328.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2167)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725408 sequences (100000180 bp) in 2.630 CPU sec, 2.637 real sec...
[M::mem_process_seqs] Processed 726042 reads in 205.874 CPU sec, 6.620 real sec
[M::mem_process_seqs] Processed 725826 reads in 146.639 CPU sec, 4.649 real sec
sorting block 96, #reads = 1075853 mem = 536880943 peak = 1099481088
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (111, 286673, 85, 109)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 354, 1019)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2589)
[M::mem_pestat] mean and std.dev: (609.10, 528.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3374)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 508)
[M::mem_pestat] mean and std.dev: (200.13, 92.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 634)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (293, 502, 1248)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3158)
[M::mem_pestat] mean and std.dev: (675.64, 658.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4113)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 515, 1119)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2867)
[M::mem_pestat] mean and std.dev: (566.72, 463.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3741)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725786 sequences (100000016 bp) in 2.475 CPU sec, 2.557 real sec...
[M::process] read 725356 sequences (100000060 bp) in 1.959 CPU sec, 1.953 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (105, 286879, 82, 96)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 327, 1192)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3232)
[M::mem_pestat] mean and std.dev: (588.61, 592.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4252)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 505)
[M::mem_pestat] mean and std.dev: (199.93, 91.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 630)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 496, 1164)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3166)
[M::mem_pestat] mean and std.dev: (591.37, 566.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4167)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 418, 923)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2325)
[M::mem_pestat] mean and std.dev: (613.06, 534.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3026)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 725408 reads in 200.440 CPU sec, 6.366 real sec
[M::mem_process_seqs] Processed 725408 reads in 141.893 CPU sec, 4.525 real sec
sorting block 97, #reads = 1076355 mem = 536882771 peak = 1099481088
[M::process] read 725730 sequences (100000200 bp) in 2.356 CPU sec, 2.429 real sec...
[M::process] read 725474 sequences (100000168 bp) in 1.780 CPU sec, 1.787 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (113, 286753, 64, 105)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 580, 1352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3574)
[M::mem_pestat] mean and std.dev: (856.28, 787.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4685)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 505)
[M::mem_pestat] mean and std.dev: (199.64, 91.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 630)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (321, 844, 1729)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4545)
[M::mem_pestat] mean and std.dev: (1049.30, 1033.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5953)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (289, 640, 1858)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4996)
[M::mem_pestat] mean and std.dev: (924.77, 921.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6565)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 725730 reads in 117.830 CPU sec, 3.759 real sec
sorting block 98, #reads = 1074859 mem = 536877272 peak = 1099481088
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (105, 286767, 76, 97)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 460, 935)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2375)
[M::mem_pestat] mean and std.dev: (584.83, 520.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3095)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 502)
[M::mem_pestat] mean and std.dev: (198.90, 90.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 626)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 737, 1726)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4724)
[M::mem_pestat] mean and std.dev: (963.31, 1046.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6223)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (260, 468, 912)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2216)
[M::mem_pestat] mean and std.dev: (626.01, 538.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2868)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (93, 286625, 64, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 396, 970)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2448)
[M::mem_pestat] mean and std.dev: (596.36, 564.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3187)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 505)
[M::mem_pestat] mean and std.dev: (199.77, 91.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 630)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 447, 1296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3508)
[M::mem_pestat] mean and std.dev: (679.78, 677.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4614)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 500, 940)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2358)
[M::mem_pestat] mean and std.dev: (573.87, 455.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3067)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726074 sequences (100000091 bp) in 2.565 CPU sec, 2.578 real sec...
[M::mem_process_seqs] Processed 725786 reads in 336.419 CPU sec, 10.693 real sec
[M::mem_process_seqs] Processed 725356 reads in 274.806 CPU sec, 8.817 real sec
sorting block 99, #reads = 1075215 mem = 536878041 peak = 1099481088
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (93, 287091, 71, 98)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 348, 929)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2359)
[M::mem_pestat] mean and std.dev: (546.66, 499.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3074)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 505)
[M::mem_pestat] mean and std.dev: (199.86, 91.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 630)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 628, 1787)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4945)
[M::mem_pestat] mean and std.dev: (969.53, 1034.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6524)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 379, 854)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2102)
[M::mem_pestat] mean and std.dev: (502.04, 433.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2726)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726876 sequences (100000002 bp) in 2.971 CPU sec, 3.117 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (109, 286992, 77, 93)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 429, 1098)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2886)
[M::mem_pestat] mean and std.dev: (568.84, 542.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3780)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 180, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 502)
[M::mem_pestat] mean and std.dev: (198.67, 91.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 626)
[M::process] read 735100 sequences (100000297 bp) in 2.120 CPU sec, 2.119 real sec...
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (112, 660, 1362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3862)
[M::mem_pestat] mean and std.dev: (830.22, 833.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5112)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (263, 508, 1077)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2705)
[M::mem_pestat] mean and std.dev: (636.28, 491.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3519)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 725474 reads in 202.434 CPU sec, 6.480 real sec
sorting block 100, #reads = 1070731 mem = 536882969 peak = 1099481088
[M::mem_process_seqs] Processed 726074 reads in 141.140 CPU sec, 4.592 real sec
sorting block 101, #reads = 1072716 mem = 536880718 peak = 1099481088
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (112, 286029, 68, 88)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 434, 999)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2549)
[M::mem_pestat] mean and std.dev: (645.65, 579.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3324)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 495)
[M::mem_pestat] mean and std.dev: (197.09, 89.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 617)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 460, 1099)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2959)
[M::mem_pestat] mean and std.dev: (662.97, 630.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3889)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 649, 1141)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3029)
[M::mem_pestat] mean and std.dev: (662.43, 547.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3973)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 732846 sequences (100000017 bp) in 2.673 CPU sec, 2.716 real sec...
[M::process] read 732024 sequences (100000005 bp) in 1.930 CPU sec, 1.926 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 289882, 55, 93)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 382, 726)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1772)
[M::mem_pestat] mean and std.dev: (427.15, 336.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2295)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (124, 170, 235)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 457)
[M::mem_pestat] mean and std.dev: (185.23, 81.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 568)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 468, 1094)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3012)
[M::mem_pestat] mean and std.dev: (644.60, 710.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3971)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 391, 828)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2060)
[M::mem_pestat] mean and std.dev: (506.78, 425.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2676)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 726876 reads in 217.020 CPU sec, 7.013 real sec
[M::mem_process_seqs] Processed 735100 reads in 149.192 CPU sec, 4.768 real sec
sorting block 102, #reads = 1064178 mem = 536884463 peak = 1099481088
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (88, 289367, 64, 104)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 434, 1029)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2683)
[M::mem_pestat] mean and std.dev: (647.61, 627.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3510)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (126, 172, 239)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 465)
[M::mem_pestat] mean and std.dev: (188.50, 83.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 578)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (280, 636, 1461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3823)
[M::mem_pestat] mean and std.dev: (962.10, 953.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5004)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 718, 1138)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2950)
[M::mem_pestat] mean and std.dev: (782.82, 696.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3856)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 731282 sequences (100000160 bp) in 2.991 CPU sec, 3.081 real sec...
[M::process] read 732664 sequences (100000061 bp) in 2.019 CPU sec, 2.014 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (92, 289964, 65, 91)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 597, 1179)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3127)
[M::mem_pestat] mean and std.dev: (715.34, 654.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4101)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (126, 173, 243)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 477)
[M::mem_pestat] mean and std.dev: (190.72, 85.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 594)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 862, 1549)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4261)
[M::mem_pestat] mean and std.dev: (944.69, 964.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5617)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 376, 748)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1812)
[M::mem_pestat] mean and std.dev: (485.06, 387.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2344)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 732846 reads in 196.671 CPU sec, 6.238 real sec
[M::mem_process_seqs] Processed 732024 reads in 223.829 CPU sec, 7.231 real sec
sorting block 103, #reads = 1078304 mem = 536880068 peak = 1099481088
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (93, 289318, 52, 85)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (263, 638, 1633)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4373)
[M::mem_pestat] mean and std.dev: (877.17, 772.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5743)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 174, 243)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 475)
[M::mem_pestat] mean and std.dev: (190.91, 85.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 591)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 405, 1167)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3235)
[M::mem_pestat] mean and std.dev: (493.93, 580.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4269)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 575, 1201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3143)
[M::mem_pestat] mean and std.dev: (739.33, 600.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4114)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 731736 sequences (100000133 bp) in 3.196 CPU sec, 3.305 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (92, 289871, 53, 81)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 364, 839)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2229)
[M::mem_pestat] mean and std.dev: (528.03, 549.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2924)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (126, 172, 240)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 468)
[M::mem_pestat] mean and std.dev: (188.89, 83.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 582)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 568, 1673)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4731)
[M::mem_pestat] mean and std.dev: (768.98, 829.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6260)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 304, 794)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1968)
[M::mem_pestat] mean and std.dev: (467.77, 419.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2555)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 731564 sequences (100000270 bp) in 2.020 CPU sec, 2.026 real sec...
[M::mem_process_seqs] Processed 731282 reads in 192.745 CPU sec, 6.227 real sec
sorting block 104, #reads = 1079145 mem = 536886370 peak = 1099481088
[M::mem_process_seqs] Processed 732664 reads in 126.247 CPU sec, 4.118 real sec
sorting block 105, #reads = 1077423 mem = 536885273 peak = 1099481088
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (91, 289693, 58, 93)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 358, 1033)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2659)
[M::mem_pestat] mean and std.dev: (588.98, 506.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3472)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (126, 173, 242)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 474)
[M::mem_pestat] mean and std.dev: (190.27, 85.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 590)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (292, 653, 1500)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3916)
[M::mem_pestat] mean and std.dev: (864.85, 758.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5124)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 487, 1209)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3127)
[M::mem_pestat] mean and std.dev: (673.84, 577.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4086)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 729778 sequences (100000246 bp) in 2.844 CPU sec, 2.996 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (99, 289406, 70, 91)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 378, 905)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2377)
[M::mem_pestat] mean and std.dev: (555.31, 514.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3113)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (126, 173, 241)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 471)
[M::mem_pestat] mean and std.dev: (189.69, 84.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 586)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (94, 484, 1622)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4678)
[M::mem_pestat] mean and std.dev: (921.35, 1099.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6206)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 419, 1108)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2850)
[M::mem_pestat] mean and std.dev: (609.83, 592.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3721)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 729948 sequences (100000168 bp) in 2.028 CPU sec, 2.027 real sec...
[M::mem_process_seqs] Processed 731736 reads in 187.722 CPU sec, 6.080 real sec
[M::mem_process_seqs] Processed 731564 reads in 132.290 CPU sec, 4.232 real sec
sorting block 106, #reads = 1076778 mem = 536881799 peak = 1099481088
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (97, 289381, 70, 90)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 370, 893)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2239)
[M::mem_pestat] mean and std.dev: (572.63, 492.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2912)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 176, 246)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 484)
[M::mem_pestat] mean and std.dev: (193.13, 87.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 603)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 629, 2113)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6005)
[M::mem_pestat] mean and std.dev: (984.68, 1201.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7951)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 607, 1703)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4615)
[M::mem_pestat] mean and std.dev: (947.15, 928.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6071)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728520 sequences (100000088 bp) in 2.749 CPU sec, 2.829 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (95, 289068, 58, 97)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 345, 1419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3899)
[M::mem_pestat] mean and std.dev: (712.11, 728.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5139)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 176, 246)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 484)
[M::mem_pestat] mean and std.dev: (193.13, 87.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 603)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (276, 671, 1573)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4167)
[M::mem_pestat] mean and std.dev: (1004.52, 879.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5464)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 418, 1165)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3019)
[M::mem_pestat] mean and std.dev: (706.43, 706.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3946)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727496 sequences (100000138 bp) in 2.588 CPU sec, 2.581 real sec...
[M::mem_process_seqs] Processed 729778 reads in 206.782 CPU sec, 6.573 real sec
sorting block 107, #reads = 1077038 mem = 536878768 peak = 1099481088
[M::mem_process_seqs] Processed 729948 reads in 143.567 CPU sec, 4.593 real sec
sorting block 108, #reads = 1075165 mem = 536877559 peak = 1099481088
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (91, 288111, 95, 102)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 439, 1155)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2953)
[M::mem_pestat] mean and std.dev: (686.20, 614.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3852)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 177, 249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 491)
[M::mem_pestat] mean and std.dev: (195.13, 88.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 612)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 431, 784)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1888)
[M::mem_pestat] mean and std.dev: (393.50, 297.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2440)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 477, 912)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2366)
[M::mem_pestat] mean and std.dev: (522.33, 461.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3093)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726484 sequences (100000178 bp) in 2.518 CPU sec, 2.582 real sec...
[M::process] read 726018 sequences (100000188 bp) in 2.897 CPU sec, 2.905 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (102, 287548, 47, 101)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 475, 1112)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2996)
[M::mem_pestat] mean and std.dev: (606.29, 562.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3938)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 495)
[M::mem_pestat] mean and std.dev: (196.74, 89.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 617)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 542, 1055)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2867)
[M::mem_pestat] mean and std.dev: (672.93, 670.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3773)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 333, 936)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2350)
[M::mem_pestat] mean and std.dev: (559.56, 511.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3057)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 728520 reads in 217.339 CPU sec, 6.920 real sec
[M::mem_process_seqs] Processed 727496 reads in 157.964 CPU sec, 5.167 real sec
sorting block 109, #reads = 1076373 mem = 536879182 peak = 1099481088
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (120, 287326, 63, 104)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 358, 916)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2308)
[M::mem_pestat] mean and std.dev: (543.07, 453.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3004)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 180, 253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 499)
[M::mem_pestat] mean and std.dev: (198.00, 90.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 622)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (129, 324, 747)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1983)
[M::mem_pestat] mean and std.dev: (393.53, 379.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2601)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 433, 942)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2368)
[M::mem_pestat] mean and std.dev: (567.98, 494.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3081)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725904 sequences (100000072 bp) in 3.707 CPU sec, 3.924 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (90, 286599, 73, 91)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 340, 740)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1836)
[M::mem_pestat] mean and std.dev: (429.59, 344.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2384)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 180, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 502)
[M::mem_pestat] mean and std.dev: (198.79, 91.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 626)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 529, 1086)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2886)
[M::mem_pestat] mean and std.dev: (629.47, 568.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3786)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 356, 983)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2517)
[M::mem_pestat] mean and std.dev: (559.87, 486.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3284)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725550 sequences (100000205 bp) in 2.810 CPU sec, 2.830 real sec...
[M::mem_process_seqs] Processed 726484 reads in 237.018 CPU sec, 7.687 real sec
[M::mem_process_seqs] Processed 726018 reads in 165.538 CPU sec, 5.424 real sec
sorting block 110, #reads = 1073561 mem = 536878758 peak = 1099481088
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (98, 287378, 70, 95)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 427, 713)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1645)
[M::mem_pestat] mean and std.dev: (437.83, 322.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2111)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 180, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 502)
[M::mem_pestat] mean and std.dev: (198.60, 90.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 626)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 484, 914)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2266)
[M::mem_pestat] mean and std.dev: (568.75, 511.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2942)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 455, 960)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2370)
[M::mem_pestat] mean and std.dev: (540.54, 437.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3075)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724570 sequences (100000203 bp) in 3.671 CPU sec, 3.832 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (110, 287059, 78, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 491, 1084)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2852)
[M::mem_pestat] mean and std.dev: (661.55, 590.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3736)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 505)
[M::mem_pestat] mean and std.dev: (199.51, 91.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 630)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (125, 634, 1448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4094)
[M::mem_pestat] mean and std.dev: (741.19, 752.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5417)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 548, 1100)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2816)
[M::mem_pestat] mean and std.dev: (740.92, 647.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3674)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724318 sequences (100000003 bp) in 2.664 CPU sec, 2.667 real sec...
[M::mem_process_seqs] Processed 725904 reads in 222.995 CPU sec, 7.216 real sec
sorting block 111, #reads = 1074649 mem = 536884094 peak = 1099481088
[M::mem_process_seqs] Processed 725550 reads in 154.882 CPU sec, 4.999 real sec
sorting block 112, #reads = 1075243 mem = 536879503 peak = 1099481088
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (102, 286313, 71, 94)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 436, 978)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2536)
[M::mem_pestat] mean and std.dev: (542.54, 508.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3315)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 182, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 506)
[M::mem_pestat] mean and std.dev: (200.32, 91.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 631)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 422, 1102)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2976)
[M::mem_pestat] mean and std.dev: (634.53, 621.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3913)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 600, 1415)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3771)
[M::mem_pestat] mean and std.dev: (868.24, 786.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4949)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723842 sequences (100000040 bp) in 2.940 CPU sec, 3.053 real sec...
[M::process] read 724708 sequences (100000249 bp) in 2.178 CPU sec, 2.178 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (115, 287026, 67, 100)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 557, 1832)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5062)
[M::mem_pestat] mean and std.dev: (1001.64, 1048.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6677)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 182, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 509)
[M::mem_pestat] mean and std.dev: (201.02, 92.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 635)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 595, 1935)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5395)
[M::mem_pestat] mean and std.dev: (1092.92, 1353.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7125)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 445, 956)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2440)
[M::mem_pestat] mean and std.dev: (614.04, 517.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3182)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724570 reads in 198.386 CPU sec, 6.387 real sec
[M::mem_process_seqs] Processed 724318 reads in 138.029 CPU sec, 4.611 real sec
sorting block 113, #reads = 1075113 mem = 536880058 peak = 1099481088
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (94, 286764, 79, 95)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 472, 928)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2334)
[M::mem_pestat] mean and std.dev: (562.53, 454.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3037)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 182, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 509)
[M::mem_pestat] mean and std.dev: (201.17, 92.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 635)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 534, 1407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3841)
[M::mem_pestat] mean and std.dev: (715.41, 740.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5058)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 387, 914)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2356)
[M::mem_pestat] mean and std.dev: (494.28, 421.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3077)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724596 sequences (100000202 bp) in 3.471 CPU sec, 3.591 real sec...
[M::process] read 99318 sequences (13675881 bp) in 0.500 CPU sec, 0.501 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (95, 286205, 65, 109)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (277, 493, 1022)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2512)
[M::mem_pestat] mean and std.dev: (617.49, 538.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3257)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 515)
[M::mem_pestat] mean and std.dev: (202.11, 93.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 643)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 578, 1083)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2879)
[M::mem_pestat] mean and std.dev: (602.86, 581.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3777)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 354, 1281)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3443)
[M::mem_pestat] mean and std.dev: (730.87, 802.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4524)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724708 reads in 201.622 CPU sec, 6.656 real sec
sorting block 114, #reads = 1076424 mem = 536879892 peak = 1099481088
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (98, 286721, 72, 113)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 484, 1913)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5351)
[M::mem_pestat] mean and std.dev: (950.68, 992.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7070)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 182, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 506)
[M::mem_pestat] mean and std.dev: (200.47, 92.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 631)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (305, 791, 1422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3656)
[M::mem_pestat] mean and std.dev: (904.70, 740.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4773)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 614, 1575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4231)
[M::mem_pestat] mean and std.dev: (824.42, 788.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5559)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724596 reads in 110.845 CPU sec, 3.652 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (13, 39278, 12, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 241, 1766)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4944)
[M::mem_pestat] mean and std.dev: (659.15, 751.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6533)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 179, 253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 499)
[M::mem_pestat] mean and std.dev: (197.70, 89.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 622)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (311, 1100, 1326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3356)
[M::mem_pestat] mean and std.dev: (795.55, 522.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4371)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 636, 909)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2245)
[M::mem_pestat] mean and std.dev: (635.87, 447.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2913)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 99318 reads in 45.439 CPU sec, 1.483 real sec
[M::mem_process_seqs] Processed 723842 reads in 355.508 CPU sec, 12.163 real sec
sorting block 115, #reads = 1073253 mem = 536879812 peak = 1099481088
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000c06f2
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: INTEL(R) XEON(R) PLATINUM 8559C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 124260328
overall: 70227341312 mem 23070.353 user 614.957 sys 785.215 real
sorting block 116, #reads = 688723 mem = 343932904 peak = 1164943360
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1029_BICJ-T1-TDNA-1_A23MHWWLT4_1.L002\tPU:L002\tSM:1029_BICJ-T1-TDNA-1_A23MHWWLT4_1\tLB:1029_BICJ-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1029_BICJ-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1029_BICJ-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 785.302 sec; CPU: 23685.361 sec
uniq header count 1
merging 117 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000c06f2
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: INTEL(R) XEON(R) PLATINUM 8559C
threads: 31 max 192
algo: util-sort
license: sentieon:util=1
output file size: 6797503786
output reads: 125655393
bam_mem_sort: 117 calls 68.950 user 2.513 sys 71.662 real
bam_write: 117 calls 49.860 user 2.604 sys 56.476 real
execute: 1 calls 48.129 user 4.010 sys 843.064 real
merge_files: 1 calls 48.094 user 3.984 sys 57.182 real
parse_chunk: 1867 calls 105.688 user 25.897 sys 134.937 real
read_chunk: 5069 calls 67.557 user 37.206 sys 736.080 real
sort_block: 1 calls 42.504 user 36.178 sys 703.715 real
write_chunk: 3200 calls 47.555 user 3.464 sys 55.700 real
overall: 3729170432 mem 2092.898 user 104.307 sys 843.085 real
ls: cannot access '*.cram': No such file or directory