Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/16/59a9801fa585f4aa7d2a38e87f4ae8/.command.sh
  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta.fai
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/74/09dfc81b1f8ad525e84ba26655eb58/1136_253-T1-TDNA-1_A23MHWWLT4_1/1136_253-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz
  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/BWAIndex
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/16/59a9801fa585f4aa7d2a38e87f4ae8/.command.run
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/74/09dfc81b1f8ad525e84ba26655eb58/1136_253-T1-TDNA-1_A23MHWWLT4_1/1136_253-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
==> STAGING COMPLETE (7 inputs)

cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1136_253-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 1928.177 CPU sec, 77.972 real sec
[M::process] read 685842 sequences (100000157 bp) in 0.982 CPU sec, 0.991 real sec...
[M::process] read 685466 sequences (100000071 bp) in 1.129 CPU sec, 1.122 real sec...
[M::process] read 684346 sequences (100000018 bp) in 1.098 CPU sec, 1.105 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 279577, 16, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 213, 674)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1618)
[M::mem_pestat] mean and std.dev: (312.67, 225.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2090)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 304, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 902)
[M::mem_pestat] mean and std.dev: (325.28, 159.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1137)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 2264, 6594)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 19380)
[M::mem_pestat] mean and std.dev: (2710.75, 2808.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 25773)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 371, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 916)
[M::mem_pestat] mean and std.dev: (311.68, 106.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1141)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683866 sequences (100000038 bp) in 1.099 CPU sec, 1.101 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 278622, 8, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (258, 417, 420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 744)
[M::mem_pestat] mean and std.dev: (351.15, 141.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 916)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 313, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 919)
[M::mem_pestat] mean and std.dev: (332.58, 161.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1158)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 343, 941)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2359)
[M::mem_pestat] mean and std.dev: (473.56, 430.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3068)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 279245, 8, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 469, 750)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1860)
[M::mem_pestat] mean and std.dev: (473.04, 342.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2415)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 309, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 912)
[M::mem_pestat] mean and std.dev: (328.18, 160.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1150)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 216, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 972)
[M::mem_pestat] mean and std.dev: (309.07, 191.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1235)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 685842 reads in 248.658 CPU sec, 7.926 real sec
[M::mem_process_seqs] Processed 684346 reads in 186.170 CPU sec, 5.991 real sec
[M::mem_process_seqs] Processed 685466 reads in 205.633 CPU sec, 6.619 real sec
sorting block 0, #reads = 1069441 mem = 536877971 peak = 602292224
[M::process] read 683512 sequences (100000108 bp) in 2.256 CPU sec, 2.545 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 277943, 11, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 226, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1012)
[M::mem_pestat] mean and std.dev: (298.57, 206.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1297)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 318, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 936)
[M::mem_pestat] mean and std.dev: (336.47, 163.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1180)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (5, 338, 1929)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5777)
[M::mem_pestat] mean and std.dev: (832.91, 856.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7701)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 269, 518)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1108)
[M::mem_pestat] mean and std.dev: (309.54, 158.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1403)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683196 sequences (100000015 bp) in 1.840 CPU sec, 1.884 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 278168, 12, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 290, 477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1101)
[M::mem_pestat] mean and std.dev: (286.93, 186.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1413)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 320, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 938)
[M::mem_pestat] mean and std.dev: (338.71, 164.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1182)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1155, 1813, 5186)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13248)
[M::mem_pestat] mean and std.dev: (2411.58, 1962.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17279)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 475, 603)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1365)
[M::mem_pestat] mean and std.dev: (413.33, 248.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1746)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683106 sequences (100000235 bp) in 1.570 CPU sec, 1.567 real sec...
[M::mem_process_seqs] Processed 683866 reads in 182.036 CPU sec, 5.816 real sec
sorting block 1, #reads = 1068779 mem = 536876892 peak = 789463040
[M::mem_process_seqs] Processed 683512 reads in 120.106 CPU sec, 3.820 real sec
sorting block 2, #reads = 1068759 mem = 536879689 peak = 870305792
[M::process] read 682620 sequences (100000102 bp) in 2.217 CPU sec, 2.338 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 277718, 17, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 274, 410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 962)
[M::mem_pestat] mean and std.dev: (237.86, 128.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1238)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 323, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 943)
[M::mem_pestat] mean and std.dev: (341.00, 164.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1188)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (308, 985, 2103)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5693)
[M::mem_pestat] mean and std.dev: (935.00, 750.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7488)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 363, 725)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1723)
[M::mem_pestat] mean and std.dev: (391.53, 308.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2222)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681932 sequences (100000115 bp) in 1.757 CPU sec, 1.763 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 278217, 16, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 284, 1170)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3026)
[M::mem_pestat] mean and std.dev: (791.31, 891.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4359)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 324, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 943)
[M::mem_pestat] mean and std.dev: (341.43, 164.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1188)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (109, 706, 1348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3826)
[M::mem_pestat] mean and std.dev: (813.62, 806.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5065)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (258, 301, 376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (22, 612)
[M::mem_pestat] mean and std.dev: (290.16, 78.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 730)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683196 reads in 172.099 CPU sec, 5.459 real sec
[M::mem_process_seqs] Processed 683106 reads in 113.305 CPU sec, 3.610 real sec
sorting block 3, #reads = 1069718 mem = 536882215 peak = 870305792
[M::process] read 682224 sequences (100000156 bp) in 1.975 CPU sec, 2.089 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 278112, 31, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 317, 1615)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4453)
[M::mem_pestat] mean and std.dev: (912.45, 824.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5872)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 326, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 942)
[M::mem_pestat] mean and std.dev: (343.02, 164.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1186)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 928, 1071)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2827)
[M::mem_pestat] mean and std.dev: (823.79, 722.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3713)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 331, 557)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1197)
[M::mem_pestat] mean and std.dev: (344.39, 166.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1517)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682944 sequences (100000294 bp) in 1.440 CPU sec, 1.437 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 278983, 13, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 403, 1016)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2624)
[M::mem_pestat] mean and std.dev: (496.51, 350.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3428)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 329, 460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 956)
[M::mem_pestat] mean and std.dev: (346.37, 166.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1204)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (398, 398, 998)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2198)
[M::mem_pestat] mean and std.dev: (536.31, 342.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2798)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 408, 595)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1409)
[M::mem_pestat] mean and std.dev: (462.94, 334.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1816)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 278102, 9, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (257, 301, 608)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1310)
[M::mem_pestat] mean and std.dev: (372.19, 197.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1661)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 331, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 962)
[M::mem_pestat] mean and std.dev: (347.76, 167.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1212)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 368, 483)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1003)
[M::mem_pestat] mean and std.dev: (380.78, 174.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1263)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682620 reads in 241.882 CPU sec, 7.749 real sec
[M::mem_process_seqs] Processed 681932 reads in 183.261 CPU sec, 5.906 real sec
sorting block 4, #reads = 1069439 mem = 536878317 peak = 870305792
[M::mem_process_seqs] Processed 682224 reads in 201.022 CPU sec, 6.500 real sec
[M::process] read 683086 sequences (100000243 bp) in 2.018 CPU sec, 2.218 real sec...
sorting block 5, #reads = 1070020 mem = 536880124 peak = 870305792
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 278533, 24, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 337, 401)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 737)
[M::mem_pestat] mean and std.dev: (303.10, 99.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 905)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 328, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 963)
[M::mem_pestat] mean and std.dev: (345.89, 167.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1214)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (470, 1872, 3761)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10343)
[M::mem_pestat] mean and std.dev: (1894.21, 1706.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13634)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 359, 1218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3206)
[M::mem_pestat] mean and std.dev: (612.16, 603.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4200)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682992 sequences (100000110 bp) in 2.329 CPU sec, 2.435 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 278498, 10, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (252, 331, 530)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1086)
[M::mem_pestat] mean and std.dev: (366.35, 155.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1364)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 323, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 945)
[M::mem_pestat] mean and std.dev: (340.70, 165.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1191)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 231, 427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 967)
[M::mem_pestat] mean and std.dev: (229.25, 106.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1237)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 350, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 896)
[M::mem_pestat] mean and std.dev: (311.46, 172.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1120)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682944 reads in 173.444 CPU sec, 5.622 real sec
[M::mem_process_seqs] Processed 683086 reads in 113.848 CPU sec, 3.594 real sec
[M::process] read 682706 sequences (100000221 bp) in 1.817 CPU sec, 1.888 real sec...
sorting block 6, #reads = 1069690 mem = 536881005 peak = 870305792
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 277852, 11, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 258, 401)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 849)
[M::mem_pestat] mean and std.dev: (272.30, 132.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1073)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 323, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 946)
[M::mem_pestat] mean and std.dev: (342.19, 166.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1192)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 483, 618)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1456)
[M::mem_pestat] mean and std.dev: (368.20, 198.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1875)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 332, 599)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1453)
[M::mem_pestat] mean and std.dev: (452.55, 382.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1983)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682486 sequences (100000118 bp) in 2.050 CPU sec, 2.194 real sec...
[M::process] read 682328 sequences (100000040 bp) in 1.500 CPU sec, 1.496 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 277949, 9, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 286, 311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 537)
[M::mem_pestat] mean and std.dev: (256.42, 100.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 658)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 326, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 954)
[M::mem_pestat] mean and std.dev: (344.22, 166.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1202)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 258, 480)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1018)
[M::mem_pestat] mean and std.dev: (322.59, 176.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1287)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682992 reads in 174.111 CPU sec, 5.569 real sec
sorting block 7, #reads = 1070704 mem = 536879836 peak = 870305792
[M::mem_process_seqs] Processed 682706 reads in 120.897 CPU sec, 3.869 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 278219, 15, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 199, 422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 974)
[M::mem_pestat] mean and std.dev: (240.87, 145.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1250)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 326, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 948)
[M::mem_pestat] mean and std.dev: (343.74, 165.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1194)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (394, 636, 636)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1120)
[M::mem_pestat] mean and std.dev: (506.08, 184.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1362)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (278, 333, 603)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1253)
[M::mem_pestat] mean and std.dev: (402.84, 238.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1578)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 8, #reads = 1069572 mem = 536879281 peak = 870305792
[M::process] read 682682 sequences (100000167 bp) in 2.411 CPU sec, 2.570 real sec...
[M::process] read 682356 sequences (100000194 bp) in 1.880 CPU sec, 1.874 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 277832, 10, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 283, 422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 924)
[M::mem_pestat] mean and std.dev: (299.29, 169.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1175)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 325, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 954)
[M::mem_pestat] mean and std.dev: (344.19, 165.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1202)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (106, 616, 1750)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5038)
[M::mem_pestat] mean and std.dev: (532.62, 546.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6682)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 374, 451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 961)
[M::mem_pestat] mean and std.dev: (327.26, 160.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1216)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682486 reads in 175.641 CPU sec, 5.596 real sec
[M::mem_process_seqs] Processed 682328 reads in 114.332 CPU sec, 3.635 real sec
sorting block 9, #reads = 1069650 mem = 536879508 peak = 870305792
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 277871, 10, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 401, 492)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1078)
[M::mem_pestat] mean and std.dev: (334.91, 159.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1371)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 323, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 947)
[M::mem_pestat] mean and std.dev: (341.88, 165.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1193)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (314, 739, 1060)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2552)
[M::mem_pestat] mean and std.dev: (814.50, 640.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3378)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 240, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (262.27, 124.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682102 sequences (100000180 bp) in 2.367 CPU sec, 2.515 real sec...
[M::process] read 682278 sequences (100000130 bp) in 1.900 CPU sec, 1.896 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 277810, 19, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 383, 519)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1175)
[M::mem_pestat] mean and std.dev: (367.97, 212.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1503)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 323, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 934)
[M::mem_pestat] mean and std.dev: (341.58, 163.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1175)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (454, 1052, 1590)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3862)
[M::mem_pestat] mean and std.dev: (1035.32, 678.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4998)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 241, 540)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1304)
[M::mem_pestat] mean and std.dev: (347.67, 248.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1686)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682682 reads in 175.475 CPU sec, 5.589 real sec
[M::mem_process_seqs] Processed 682356 reads in 113.437 CPU sec, 3.605 real sec
sorting block 10, #reads = 1069645 mem = 536888647 peak = 870305792
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 277720, 11, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 324, 708)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1636)
[M::mem_pestat] mean and std.dev: (441.27, 271.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2100)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 322, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 930)
[M::mem_pestat] mean and std.dev: (339.93, 162.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1170)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1330, 1330, 2096)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3628)
[M::mem_pestat] mean and std.dev: (1551.50, 488.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4394)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 290, 377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 651)
[M::mem_pestat] mean and std.dev: (287.48, 104.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 788)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 684888 sequences (100000003 bp) in 2.861 CPU sec, 3.004 real sec...
[M::process] read 682262 sequences (100000210 bp) in 1.959 CPU sec, 1.961 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 277904, 6, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 334, 750)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1820)
[M::mem_pestat] mean and std.dev: (450.27, 344.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2355)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 320, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 917)
[M::mem_pestat] mean and std.dev: (337.04, 160.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1153)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 350, 614)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1390)
[M::mem_pestat] mean and std.dev: (391.62, 253.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1778)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682102 reads in 179.868 CPU sec, 5.719 real sec
[M::mem_process_seqs] Processed 682278 reads in 114.644 CPU sec, 3.644 real sec
sorting block 11, #reads = 1069062 mem = 536889244 peak = 870305792
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 278599, 17, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 310, 389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 705)
[M::mem_pestat] mean and std.dev: (286.90, 106.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 863)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 305, 425)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 877)
[M::mem_pestat] mean and std.dev: (322.09, 153.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1103)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1961, 5459, 7227)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 17759)
[M::mem_pestat] mean and std.dev: (4099.06, 2991.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 23025)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 375, 666)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1614)
[M::mem_pestat] mean and std.dev: (387.10, 231.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2088)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682544 sequences (100000020 bp) in 2.849 CPU sec, 3.064 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 277878, 19, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (260, 493, 1120)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2840)
[M::mem_pestat] mean and std.dev: (514.33, 401.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3700)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 317, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 912)
[M::mem_pestat] mean and std.dev: (335.09, 159.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1147)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 869, 1578)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4410)
[M::mem_pestat] mean and std.dev: (678.12, 596.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5826)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (262, 429, 901)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2179)
[M::mem_pestat] mean and std.dev: (548.03, 389.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2818)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682214 sequences (100000013 bp) in 1.700 CPU sec, 1.697 real sec...
[M::mem_process_seqs] Processed 684888 reads in 181.342 CPU sec, 5.771 real sec
sorting block 12, #reads = 1068983 mem = 536880051 peak = 870305792
[M::mem_process_seqs] Processed 682262 reads in 117.861 CPU sec, 3.737 real sec
sorting block 13, #reads = 1065207 mem = 536878758 peak = 877367296
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 277635, 2, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 214, 618)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1572)
[M::mem_pestat] mean and std.dev: (463.87, 432.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2194)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 317, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 913)
[M::mem_pestat] mean and std.dev: (335.64, 160.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1148)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 331, 772)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1878)
[M::mem_pestat] mean and std.dev: (441.44, 301.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2431)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682006 sequences (100000114 bp) in 2.477 CPU sec, 2.650 real sec...
[M::process] read 681858 sequences (100000047 bp) in 1.650 CPU sec, 1.655 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 276913, 8, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 368, 1881)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5285)
[M::mem_pestat] mean and std.dev: (770.21, 896.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6987)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 318, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 917)
[M::mem_pestat] mean and std.dev: (337.59, 161.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1153)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 292, 657)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1541)
[M::mem_pestat] mean and std.dev: (379.12, 281.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1983)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682544 reads in 171.279 CPU sec, 5.447 real sec
[M::mem_process_seqs] Processed 682214 reads in 111.858 CPU sec, 3.561 real sec
sorting block 14, #reads = 1068665 mem = 536880307 peak = 877367296
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 276967, 9, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 322, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 963)
[M::mem_pestat] mean and std.dev: (260.58, 122.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1226)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 318, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 917)
[M::mem_pestat] mean and std.dev: (337.41, 161.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1153)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 384, 527)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1201)
[M::mem_pestat] mean and std.dev: (320.65, 157.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1538)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681734 sequences (100000179 bp) in 2.572 CPU sec, 2.774 real sec...
[M::process] read 681482 sequences (100000267 bp) in 1.630 CPU sec, 1.622 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 277142, 8, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 379, 505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1161)
[M::mem_pestat] mean and std.dev: (330.44, 187.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1489)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 318, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 914)
[M::mem_pestat] mean and std.dev: (336.73, 160.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1149)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 291, 602)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1312)
[M::mem_pestat] mean and std.dev: (370.84, 240.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1667)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682006 reads in 179.053 CPU sec, 5.946 real sec
[M::mem_process_seqs] Processed 681858 reads in 117.281 CPU sec, 3.740 real sec
sorting block 15, #reads = 1068666 mem = 536877605 peak = 877367296
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 277021, 18, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 270, 613)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1475)
[M::mem_pestat] mean and std.dev: (453.44, 386.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2000)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 320, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 916)
[M::mem_pestat] mean and std.dev: (338.31, 160.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1151)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (357, 683, 3569)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9993)
[M::mem_pestat] mean and std.dev: (2088.61, 2515.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13205)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (275, 358, 481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 893)
[M::mem_pestat] mean and std.dev: (313.32, 133.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1099)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681520 sequences (100000168 bp) in 2.632 CPU sec, 2.841 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 277383, 27, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 255, 652)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1592)
[M::mem_pestat] mean and std.dev: (358.84, 246.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2062)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 323, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 918)
[M::mem_pestat] mean and std.dev: (340.95, 161.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1153)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (371, 707, 884)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1910)
[M::mem_pestat] mean and std.dev: (644.20, 470.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2525)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 341, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 910)
[M::mem_pestat] mean and std.dev: (311.33, 181.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1144)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681582 sequences (100000238 bp) in 1.610 CPU sec, 1.605 real sec...
[M::mem_process_seqs] Processed 681734 reads in 169.560 CPU sec, 5.390 real sec
sorting block 16, #reads = 1067714 mem = 536879838 peak = 877367296
[M::mem_process_seqs] Processed 681482 reads in 112.112 CPU sec, 3.556 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 277172, 21, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 236, 507)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1189)
[M::mem_pestat] mean and std.dev: (316.65, 174.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1530)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 323, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 923)
[M::mem_pestat] mean and std.dev: (340.89, 161.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1160)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 320, 1107)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2907)
[M::mem_pestat] mean and std.dev: (552.05, 450.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3807)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (326, 408, 1437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3659)
[M::mem_pestat] mean and std.dev: (559.24, 516.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4770)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 17, #reads = 1068210 mem = 536882441 peak = 877367296
[M::process] read 681220 sequences (100000269 bp) in 2.840 CPU sec, 2.997 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 278148, 16, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 202, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 959)
[M::mem_pestat] mean and std.dev: (239.27, 125.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1223)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 322, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 919)
[M::mem_pestat] mean and std.dev: (339.74, 161.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1155)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1062, 2579, 4028)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9960)
[M::mem_pestat] mean and std.dev: (2386.00, 1507.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12926)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 249, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653)
[M::mem_pestat] mean and std.dev: (235.19, 82.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 810)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681920 sequences (100000031 bp) in 1.677 CPU sec, 1.685 real sec...
[M::mem_process_seqs] Processed 681520 reads in 168.017 CPU sec, 5.325 real sec
[M::mem_process_seqs] Processed 681582 reads in 109.361 CPU sec, 3.466 real sec
sorting block 18, #reads = 1067636 mem = 536878846 peak = 877367296
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 277485, 14, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 369, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1011)
[M::mem_pestat] mean and std.dev: (287.03, 150.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1295)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 324, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 919)
[M::mem_pestat] mean and std.dev: (341.79, 162.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1154)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (404, 996, 999)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2189)
[M::mem_pestat] mean and std.dev: (696.67, 414.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2784)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 442, 663)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1549)
[M::mem_pestat] mean and std.dev: (439.79, 309.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1992)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 684120 sequences (100000054 bp) in 2.651 CPU sec, 2.801 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 277951, 16, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (252, 310, 1092)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2772)
[M::mem_pestat] mean and std.dev: (649.13, 626.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3612)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 320, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 920)
[M::mem_pestat] mean and std.dev: (338.43, 161.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1157)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (410, 1181, 1547)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3821)
[M::mem_pestat] mean and std.dev: (993.93, 622.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4958)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 323, 534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1152)
[M::mem_pestat] mean and std.dev: (350.22, 187.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1461)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683856 sequences (100000188 bp) in 1.570 CPU sec, 1.570 real sec...
[M::mem_process_seqs] Processed 681220 reads in 170.659 CPU sec, 5.440 real sec
[M::mem_process_seqs] Processed 681920 reads in 123.403 CPU sec, 3.939 real sec
sorting block 19, #reads = 1069179 mem = 536877484 peak = 877367296
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 278565, 7, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 231, 501)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1153)
[M::mem_pestat] mean and std.dev: (319.09, 263.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1479)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 313, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 919)
[M::mem_pestat] mean and std.dev: (332.38, 161.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1158)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 289, 762)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1898)
[M::mem_pestat] mean and std.dev: (346.52, 208.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2466)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683508 sequences (100000158 bp) in 2.749 CPU sec, 2.934 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 278341, 11, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 407, 1317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3517)
[M::mem_pestat] mean and std.dev: (645.29, 714.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4617)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 317, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 927)
[M::mem_pestat] mean and std.dev: (335.58, 163.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1168)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (12, 4657, 4657)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13947)
[M::mem_pestat] mean and std.dev: (2886.00, 2568.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 18592)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 326, 529)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1133)
[M::mem_pestat] mean and std.dev: (360.93, 193.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1435)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682952 sequences (100000293 bp) in 1.619 CPU sec, 1.623 real sec...
[M::mem_process_seqs] Processed 684120 reads in 169.276 CPU sec, 5.391 real sec
[M::mem_process_seqs] Processed 683856 reads in 109.147 CPU sec, 3.462 real sec
sorting block 20, #reads = 1068983 mem = 536884823 peak = 877367296
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 278427, 6, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 255, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (259.52, 137.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 856)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 318, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 937)
[M::mem_pestat] mean and std.dev: (337.80, 164.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1181)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (289, 337, 484)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 874)
[M::mem_pestat] mean and std.dev: (346.34, 176.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1069)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682904 sequences (100000222 bp) in 3.411 CPU sec, 3.619 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 278404, 33, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 294, 643)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1505)
[M::mem_pestat] mean and std.dev: (366.94, 255.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1936)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 323, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 946)
[M::mem_pestat] mean and std.dev: (342.28, 166.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1192)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (676, 1021, 1275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2473)
[M::mem_pestat] mean and std.dev: (1001.41, 486.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3072)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 262, 541)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1227)
[M::mem_pestat] mean and std.dev: (333.42, 258.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1570)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683508 reads in 167.485 CPU sec, 5.369 real sec
sorting block 21, #reads = 1071848 mem = 536877995 peak = 877367296
[M::mem_process_seqs] Processed 682952 reads in 111.089 CPU sec, 3.541 real sec
[M::process] read 682470 sequences (100000098 bp) in 1.850 CPU sec, 1.912 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 278441, 11, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 397, 561)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1251)
[M::mem_pestat] mean and std.dev: (397.35, 176.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1596)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 326, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 956)
[M::mem_pestat] mean and std.dev: (344.64, 167.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1205)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (695, 2713, 2796)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6998)
[M::mem_pestat] mean and std.dev: (1874.82, 1195.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9099)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 395, 1375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3675)
[M::mem_pestat] mean and std.dev: (789.61, 764.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4825)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 22, #reads = 1070463 mem = 536885550 peak = 911769600
[M::process] read 682482 sequences (100000238 bp) in 2.341 CPU sec, 2.520 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 278842, 8, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (132, 255, 423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1005)
[M::mem_pestat] mean and std.dev: (286.42, 196.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1296)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 327, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 966)
[M::mem_pestat] mean and std.dev: (346.90, 169.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1218)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 393, 683)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1585)
[M::mem_pestat] mean and std.dev: (398.43, 290.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2036)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682046 sequences (100000125 bp) in 1.576 CPU sec, 1.580 real sec...
[M::mem_process_seqs] Processed 682904 reads in 165.964 CPU sec, 5.299 real sec
[M::mem_process_seqs] Processed 682470 reads in 112.071 CPU sec, 3.555 real sec
sorting block 23, #reads = 1072305 mem = 536880303 peak = 911769600
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 278487, 3, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (258, 381, 648)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1428)
[M::mem_pestat] mean and std.dev: (347.27, 141.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1818)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 329, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 961)
[M::mem_pestat] mean and std.dev: (346.72, 168.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1211)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 372, 1479)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4059)
[M::mem_pestat] mean and std.dev: (471.74, 440.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5349)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681504 sequences (100000015 bp) in 2.999 CPU sec, 3.143 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 278156, 12, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 335, 1018)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2604)
[M::mem_pestat] mean and std.dev: (426.53, 324.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3397)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 331, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 965)
[M::mem_pestat] mean and std.dev: (348.18, 167.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1216)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (496, 496, 652)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (184, 964)
[M::mem_pestat] mean and std.dev: (489.89, 125.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1120)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 251, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 978)
[M::mem_pestat] mean and std.dev: (315.43, 152.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1234)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682482 reads in 163.529 CPU sec, 5.198 real sec
[M::process] read 681586 sequences (100000063 bp) in 2.102 CPU sec, 2.136 real sec...
[M::mem_process_seqs] Processed 682046 reads in 115.189 CPU sec, 3.649 real sec
sorting block 24, #reads = 1071478 mem = 536877386 peak = 911769600
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 277853, 7, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 294, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 710)
[M::mem_pestat] mean and std.dev: (299.69, 140.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 878)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 333, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 970)
[M::mem_pestat] mean and std.dev: (350.73, 168.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1222)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (289, 345, 427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (13, 703)
[M::mem_pestat] mean and std.dev: (319.62, 88.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 841)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681700 sequences (100000016 bp) in 2.506 CPU sec, 2.647 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 277813, 8, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 226, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1041)
[M::mem_pestat] mean and std.dev: (316.84, 203.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1328)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 334, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 974)
[M::mem_pestat] mean and std.dev: (352.05, 169.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1227)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 365, 419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 805)
[M::mem_pestat] mean and std.dev: (318.60, 133.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 998)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682656 sequences (100000182 bp) in 1.550 CPU sec, 1.548 real sec...
[M::mem_process_seqs] Processed 681504 reads in 166.942 CPU sec, 5.325 real sec
sorting block 25, #reads = 1069361 mem = 536878646 peak = 911769600
[M::mem_process_seqs] Processed 681586 reads in 120.120 CPU sec, 3.830 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 277991, 13, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 406, 3166)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9154)
[M::mem_pestat] mean and std.dev: (1592.61, 2514.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12148)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 334, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 973)
[M::mem_pestat] mean and std.dev: (351.23, 169.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1226)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1069, 1069, 1985)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3817)
[M::mem_pestat] mean and std.dev: (1136.00, 413.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4733)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 389, 1003)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2631)
[M::mem_pestat] mean and std.dev: (505.55, 505.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3445)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 26, #reads = 1070622 mem = 536880124 peak = 911769600
[M::process] read 682514 sequences (100000095 bp) in 2.775 CPU sec, 2.938 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 278010, 12, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 409, 982)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2598)
[M::mem_pestat] mean and std.dev: (525.44, 496.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3406)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 325, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 953)
[M::mem_pestat] mean and std.dev: (343.87, 167.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1201)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (695, 1453, 1895)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4295)
[M::mem_pestat] mean and std.dev: (1256.75, 704.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5495)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 378, 795)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1915)
[M::mem_pestat] mean and std.dev: (508.88, 428.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2475)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681700 reads in 166.166 CPU sec, 5.284 real sec
[M::process] read 682348 sequences (100000054 bp) in 1.981 CPU sec, 1.992 real sec...
[M::mem_process_seqs] Processed 682656 reads in 109.423 CPU sec, 3.461 real sec
sorting block 27, #reads = 1069630 mem = 536879699 peak = 911769600
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 279077, 9, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 295, 395)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 721)
[M::mem_pestat] mean and std.dev: (266.24, 87.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 884)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 327, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 957)
[M::mem_pestat] mean and std.dev: (345.20, 167.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1206)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 273, 739)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1791)
[M::mem_pestat] mean and std.dev: (331.33, 251.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2317)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682500 sequences (100000059 bp) in 2.396 CPU sec, 2.544 real sec...
[M::process] read 681936 sequences (100000237 bp) in 1.880 CPU sec, 1.885 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 277791, 9, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 396, 1522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4212)
[M::mem_pestat] mean and std.dev: (869.59, 1035.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5557)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 325, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 954)
[M::mem_pestat] mean and std.dev: (344.22, 166.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1202)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 421, 705)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1667)
[M::mem_pestat] mean and std.dev: (526.84, 383.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2148)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682514 reads in 167.369 CPU sec, 5.548 real sec
[M::mem_process_seqs] Processed 682348 reads in 108.399 CPU sec, 3.435 real sec
sorting block 28, #reads = 1070473 mem = 536877611 peak = 911769600
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 277836, 12, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (324, 589, 1531)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3945)
[M::mem_pestat] mean and std.dev: (802.88, 671.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5152)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 325, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 951)
[M::mem_pestat] mean and std.dev: (344.26, 166.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1198)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 553, 2365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6763)
[M::mem_pestat] mean and std.dev: (939.92, 1078.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8962)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (313, 537, 746)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1612)
[M::mem_pestat] mean and std.dev: (564.56, 279.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2045)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682102 sequences (100000232 bp) in 2.527 CPU sec, 2.675 real sec...
[M::process] read 682092 sequences (100000145 bp) in 1.510 CPU sec, 1.512 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 277809, 12, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (350, 399, 568)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1004)
[M::mem_pestat] mean and std.dev: (400.02, 175.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1222)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 325, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 951)
[M::mem_pestat] mean and std.dev: (344.52, 167.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1198)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (398, 707, 1625)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4079)
[M::mem_pestat] mean and std.dev: (703.18, 522.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5306)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (263, 314, 385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (19, 629)
[M::mem_pestat] mean and std.dev: (279.38, 64.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 751)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682500 reads in 168.384 CPU sec, 5.369 real sec
[M::mem_process_seqs] Processed 681936 reads in 112.460 CPU sec, 3.592 real sec
sorting block 29, #reads = 1069196 mem = 536878195 peak = 911769600
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 277236, 3, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 261, 390)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 830)
[M::mem_pestat] mean and std.dev: (255.31, 153.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1050)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 322, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 938)
[M::mem_pestat] mean and std.dev: (341.52, 164.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1181)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 411, 535)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1113)
[M::mem_pestat] mean and std.dev: (425.00, 216.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1402)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682756 sequences (100000298 bp) in 2.874 CPU sec, 3.042 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 278062, 5, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 241, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 738)
[M::mem_pestat] mean and std.dev: (244.97, 88.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 923)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 321, 451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 935)
[M::mem_pestat] mean and std.dev: (340.68, 164.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1177)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 304, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 866)
[M::mem_pestat] mean and std.dev: (301.87, 108.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1079)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682790 sequences (100000227 bp) in 1.910 CPU sec, 1.908 real sec...
[M::mem_process_seqs] Processed 682102 reads in 172.706 CPU sec, 5.480 real sec
sorting block 30, #reads = 1068966 mem = 536880406 peak = 911769600
[M::mem_process_seqs] Processed 682092 reads in 121.054 CPU sec, 3.850 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 277889, 16, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 343, 843)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2121)
[M::mem_pestat] mean and std.dev: (535.69, 555.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2760)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 319, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 930)
[M::mem_pestat] mean and std.dev: (338.34, 163.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1171)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1141, 1193, 5288)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13582)
[M::mem_pestat] mean and std.dev: (2308.06, 2033.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17729)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 603, 1128)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3024)
[M::mem_pestat] mean and std.dev: (386.38, 264.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3972)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 31, #reads = 1069553 mem = 536879974 peak = 911769600
[M::process] read 683112 sequences (100000060 bp) in 2.502 CPU sec, 2.639 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 277843, 5, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 344, 604)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1394)
[M::mem_pestat] mean and std.dev: (330.37, 202.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1789)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 317, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 926)
[M::mem_pestat] mean and std.dev: (336.74, 162.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1166)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 418, 620)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1374)
[M::mem_pestat] mean and std.dev: (376.73, 256.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1751)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 684214 sequences (100000057 bp) in 1.580 CPU sec, 1.577 real sec...
[M::mem_process_seqs] Processed 682756 reads in 170.381 CPU sec, 5.431 real sec
[M::mem_process_seqs] Processed 682790 reads in 113.079 CPU sec, 3.594 real sec
sorting block 32, #reads = 1069813 mem = 536879931 peak = 911769600
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 277890, 10, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 376, 594)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1336)
[M::mem_pestat] mean and std.dev: (382.03, 243.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1707)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 315, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 921)
[M::mem_pestat] mean and std.dev: (334.70, 161.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1160)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (303, 339, 524)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 966)
[M::mem_pestat] mean and std.dev: (365.56, 116.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1187)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 305, 413)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 851)
[M::mem_pestat] mean and std.dev: (255.71, 92.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1070)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682144 sequences (100000203 bp) in 2.801 CPU sec, 2.982 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 278696, 12, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 436, 1122)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3030)
[M::mem_pestat] mean and std.dev: (591.53, 492.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3984)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 310, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 909)
[M::mem_pestat] mean and std.dev: (329.55, 159.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1145)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 522, 1529)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4075)
[M::mem_pestat] mean and std.dev: (789.58, 787.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5348)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 365, 639)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1449)
[M::mem_pestat] mean and std.dev: (379.10, 186.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1854)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682232 sequences (100000224 bp) in 2.010 CPU sec, 2.007 real sec...
[M::mem_process_seqs] Processed 683112 reads in 186.983 CPU sec, 6.200 real sec
[M::mem_process_seqs] Processed 684214 reads in 120.716 CPU sec, 3.829 real sec
sorting block 33, #reads = 1068635 mem = 536877258 peak = 911769600
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 278063, 4, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 253, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 734)
[M::mem_pestat] mean and std.dev: (264.30, 112.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 923)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 318, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 925)
[M::mem_pestat] mean and std.dev: (338.49, 163.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1164)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (268, 510, 768)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1768)
[M::mem_pestat] mean and std.dev: (469.41, 276.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2268)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682166 sequences (100000154 bp) in 2.309 CPU sec, 2.459 real sec...
[M::process] read 681796 sequences (100000011 bp) in 1.550 CPU sec, 1.545 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 278299, 9, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 250, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (8, 543)
[M::mem_pestat] mean and std.dev: (268.65, 64.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 650)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 320, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 931)
[M::mem_pestat] mean and std.dev: (339.41, 164.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1172)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 241, 557)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1271)
[M::mem_pestat] mean and std.dev: (345.93, 271.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1628)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682144 reads in 167.921 CPU sec, 5.359 real sec
sorting block 34, #reads = 1065007 mem = 536879662 peak = 911769600
[M::mem_process_seqs] Processed 682232 reads in 119.775 CPU sec, 3.829 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 278167, 14, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 355, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1056)
[M::mem_pestat] mean and std.dev: (354.33, 232.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1351)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 319, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 925)
[M::mem_pestat] mean and std.dev: (338.53, 162.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1164)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (320, 725, 1189)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2927)
[M::mem_pestat] mean and std.dev: (600.09, 344.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3796)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 310, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1049)
[M::mem_pestat] mean and std.dev: (305.50, 159.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1341)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 35, #reads = 1069250 mem = 536880533 peak = 911769600
[M::process] read 681710 sequences (100000287 bp) in 2.681 CPU sec, 2.855 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 277468, 13, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 281, 475)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1091)
[M::mem_pestat] mean and std.dev: (270.56, 148.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1399)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 320, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 923)
[M::mem_pestat] mean and std.dev: (339.38, 163.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1161)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 668, 5089)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 14969)
[M::mem_pestat] mean and std.dev: (1476.62, 2002.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 19909)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 404, 656)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1528)
[M::mem_pestat] mean and std.dev: (326.03, 155.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1964)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681834 sequences (100000229 bp) in 1.950 CPU sec, 1.951 real sec...
[M::mem_process_seqs] Processed 682166 reads in 171.910 CPU sec, 5.461 real sec
[M::mem_process_seqs] Processed 681796 reads in 114.614 CPU sec, 3.625 real sec
sorting block 36, #reads = 1069557 mem = 536877738 peak = 911769600
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 277978, 13, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (275, 336, 565)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1145)
[M::mem_pestat] mean and std.dev: (384.65, 217.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1435)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 321, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 916)
[M::mem_pestat] mean and std.dev: (339.17, 161.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1151)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (472, 541, 1852)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4612)
[M::mem_pestat] mean and std.dev: (978.00, 753.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5992)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 299, 568)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1304)
[M::mem_pestat] mean and std.dev: (346.61, 196.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1672)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681594 sequences (100000240 bp) in 3.038 CPU sec, 3.195 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 277975, 24, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 289, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1001)
[M::mem_pestat] mean and std.dev: (295.76, 139.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1270)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 320, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 916)
[M::mem_pestat] mean and std.dev: (339.04, 161.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1151)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (445, 751, 1399)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3307)
[M::mem_pestat] mean and std.dev: (814.95, 462.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4261)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 289, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 868)
[M::mem_pestat] mean and std.dev: (279.90, 128.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1087)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681710 reads in 173.560 CPU sec, 5.507 real sec
[M::process] read 681612 sequences (100000299 bp) in 2.070 CPU sec, 2.070 real sec...
[M::mem_process_seqs] Processed 681834 reads in 126.745 CPU sec, 4.027 real sec
sorting block 37, #reads = 1068440 mem = 536878017 peak = 911769600
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 277768, 14, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (130, 193, 560)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1420)
[M::mem_pestat] mean and std.dev: (286.85, 220.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1850)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 323, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 920)
[M::mem_pestat] mean and std.dev: (340.51, 162.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1156)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (689, 1047, 4028)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10706)
[M::mem_pestat] mean and std.dev: (1901.64, 1769.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14045)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 237, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 986)
[M::mem_pestat] mean and std.dev: (307.86, 172.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1255)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681342 sequences (100000089 bp) in 2.901 CPU sec, 3.068 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 277721, 19, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 366, 541)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1257)
[M::mem_pestat] mean and std.dev: (321.65, 245.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1615)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 325, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 932)
[M::mem_pestat] mean and std.dev: (342.89, 164.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1172)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (421, 760, 4828)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13642)
[M::mem_pestat] mean and std.dev: (2210.21, 2432.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 18049)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 284, 505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1013)
[M::mem_pestat] mean and std.dev: (372.74, 201.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1267)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681594 reads in 174.773 CPU sec, 5.549 real sec
[M::process] read 682382 sequences (100000255 bp) in 2.054 CPU sec, 2.053 real sec...
[M::mem_process_seqs] Processed 681612 reads in 122.459 CPU sec, 3.881 real sec
sorting block 38, #reads = 1067541 mem = 536880704 peak = 911769600
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 277804, 4, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (287, 367, 662)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1412)
[M::mem_pestat] mean and std.dev: (334.71, 232.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1787)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 328, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 943)
[M::mem_pestat] mean and std.dev: (346.48, 166.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1186)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 290, 416)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 794)
[M::mem_pestat] mean and std.dev: (304.20, 126.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 983)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 685064 sequences (100000295 bp) in 2.750 CPU sec, 2.885 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 278232, 6, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 346, 480)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1094)
[M::mem_pestat] mean and std.dev: (334.54, 221.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1401)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 323, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 939)
[M::mem_pestat] mean and std.dev: (342.13, 165.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1182)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 248, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 951)
[M::mem_pestat] mean and std.dev: (283.13, 149.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1206)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681342 reads in 170.139 CPU sec, 5.407 real sec
[M::process] read 684142 sequences (100000205 bp) in 1.970 CPU sec, 1.966 real sec...
sorting block 39, #reads = 1068644 mem = 536881569 peak = 911769600
[M::mem_process_seqs] Processed 682382 reads in 122.480 CPU sec, 3.899 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 278869, 14, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 264, 582)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1352)
[M::mem_pestat] mean and std.dev: (366.32, 273.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1737)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 310, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 923)
[M::mem_pestat] mean and std.dev: (331.27, 163.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1164)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (463, 1876, 2036)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5182)
[M::mem_pestat] mean and std.dev: (1503.14, 838.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6755)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 350, 927)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2347)
[M::mem_pestat] mean and std.dev: (607.75, 602.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3057)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 40, #reads = 1067924 mem = 536881893 peak = 917647360
[M::process] read 683524 sequences (100000255 bp) in 2.614 CPU sec, 2.764 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 279383, 13, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 284, 419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 915)
[M::mem_pestat] mean and std.dev: (272.09, 140.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1163)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 682938 sequences (100000186 bp) in 1.580 CPU sec, 1.587 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (203, 316, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 929)
[M::mem_pestat] mean and std.dev: (335.70, 164.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1171)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (446, 1038, 1645)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4043)
[M::mem_pestat] mean and std.dev: (982.92, 635.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5242)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (266, 785, 1135)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2873)
[M::mem_pestat] mean and std.dev: (656.60, 385.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3742)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 685064 reads in 175.374 CPU sec, 5.616 real sec
[M::mem_process_seqs] Processed 684142 reads in 126.710 CPU sec, 4.071 real sec
sorting block 41, #reads = 1068760 mem = 536883839 peak = 917647360
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 278426, 7, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 302, 515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1057)
[M::mem_pestat] mean and std.dev: (339.94, 196.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1328)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 321, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 938)
[M::mem_pestat] mean and std.dev: (339.50, 165.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1182)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 394, 728)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1774)
[M::mem_pestat] mean and std.dev: (475.79, 360.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2297)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682448 sequences (100000060 bp) in 2.909 CPU sec, 3.051 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 278221, 13, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 253, 543)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1323)
[M::mem_pestat] mean and std.dev: (291.33, 203.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1713)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 324, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 949)
[M::mem_pestat] mean and std.dev: (342.16, 166.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1196)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 564, 3193)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9303)
[M::mem_pestat] mean and std.dev: (1055.46, 1201.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12358)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 241, 514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1138)
[M::mem_pestat] mean and std.dev: (291.39, 183.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1450)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683524 reads in 175.348 CPU sec, 5.574 real sec
[M::process] read 682328 sequences (100000203 bp) in 2.026 CPU sec, 2.038 real sec...
[M::mem_process_seqs] Processed 682938 reads in 115.471 CPU sec, 3.879 real sec
sorting block 42, #reads = 1069420 mem = 536878288 peak = 917647360
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 278573, 3, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (336, 601, 1691)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4401)
[M::mem_pestat] mean and std.dev: (1032.60, 910.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5756)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 327, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 957)
[M::mem_pestat] mean and std.dev: (345.32, 167.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1206)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 597, 2442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6908)
[M::mem_pestat] mean and std.dev: (1096.67, 954.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9141)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681880 sequences (100000041 bp) in 2.473 CPU sec, 2.607 real sec...
[M::process] read 681634 sequences (100000070 bp) in 1.530 CPU sec, 1.531 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 278816, 9, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 314, 514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1252)
[M::mem_pestat] mean and std.dev: (313.85, 183.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1621)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 330, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 962)
[M::mem_pestat] mean and std.dev: (347.62, 168.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1212)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 302, 427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 813)
[M::mem_pestat] mean and std.dev: (288.20, 107.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1006)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682448 reads in 169.901 CPU sec, 5.647 real sec
sorting block 43, #reads = 1068985 mem = 536882328 peak = 917647360
[M::mem_process_seqs] Processed 682328 reads in 110.926 CPU sec, 3.529 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 278565, 13, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 239, 311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 589)
[M::mem_pestat] mean and std.dev: (240.58, 113.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 728)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 332, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 967)
[M::mem_pestat] mean and std.dev: (350.37, 169.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1218)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 182, 6204)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 18248)
[M::mem_pestat] mean and std.dev: (2250.31, 3227.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 24270)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 358, 433)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 939)
[M::mem_pestat] mean and std.dev: (339.74, 182.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1192)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 44, #reads = 1069209 mem = 536881337 peak = 955056128
[M::process] read 681390 sequences (100000124 bp) in 2.554 CPU sec, 2.699 real sec...
[M::process] read 681586 sequences (100000134 bp) in 1.561 CPU sec, 1.574 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 277992, 12, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (289, 369, 645)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1357)
[M::mem_pestat] mean and std.dev: (444.27, 232.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1713)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 334, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 965)
[M::mem_pestat] mean and std.dev: (350.82, 168.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1215)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (319, 506, 7564)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 22054)
[M::mem_pestat] mean and std.dev: (3223.83, 3558.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 29299)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 489, 2259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6441)
[M::mem_pestat] mean and std.dev: (1418.83, 1921.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9105)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681880 reads in 162.922 CPU sec, 5.191 real sec
[M::mem_process_seqs] Processed 681634 reads in 108.352 CPU sec, 3.454 real sec
sorting block 45, #reads = 1070779 mem = 536882533 peak = 955056128
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 278325, 14, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 445, 1251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3359)
[M::mem_pestat] mean and std.dev: (580.46, 565.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4413)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 338, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 984)
[M::mem_pestat] mean and std.dev: (355.25, 172.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1240)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (764, 1929, 2199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5069)
[M::mem_pestat] mean and std.dev: (1530.00, 816.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6504)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 338, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 902)
[M::mem_pestat] mean and std.dev: (308.17, 128.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1134)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681760 sequences (100000117 bp) in 2.857 CPU sec, 3.035 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 278304, 7, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 286, 473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 917)
[M::mem_pestat] mean and std.dev: (330.56, 155.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1139)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 338, 474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 990)
[M::mem_pestat] mean and std.dev: (356.20, 172.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1248)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (259, 313, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (91, 511)
[M::mem_pestat] mean and std.dev: (285.53, 71.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 595)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682932 sequences (100000027 bp) in 1.905 CPU sec, 1.912 real sec...
[M::mem_process_seqs] Processed 681390 reads in 180.360 CPU sec, 5.755 real sec
[M::mem_process_seqs] Processed 681586 reads in 126.423 CPU sec, 4.035 real sec
sorting block 46, #reads = 1069073 mem = 536881782 peak = 955056128
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 278123, 6, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 284, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 999)
[M::mem_pestat] mean and std.dev: (272.71, 139.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1268)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 333, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 973)
[M::mem_pestat] mean and std.dev: (351.50, 170.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1226)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 270, 810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2036)
[M::mem_pestat] mean and std.dev: (389.90, 266.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2649)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682504 sequences (100000023 bp) in 2.704 CPU sec, 2.991 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 278233, 5, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 295, 519)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1181)
[M::mem_pestat] mean and std.dev: (356.27, 218.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1512)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 324, 460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 962)
[M::mem_pestat] mean and std.dev: (344.63, 168.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1213)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 272, 675)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1609)
[M::mem_pestat] mean and std.dev: (411.02, 312.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2076)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682014 sequences (100000134 bp) in 1.947 CPU sec, 1.963 real sec...
[M::mem_process_seqs] Processed 681760 reads in 188.492 CPU sec, 6.318 real sec
[M::mem_process_seqs] Processed 682932 reads in 126.134 CPU sec, 4.086 real sec
sorting block 47, #reads = 1069813 mem = 536881724 peak = 955056128
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 278768, 6, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 318, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 927)
[M::mem_pestat] mean and std.dev: (288.26, 137.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1171)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 325, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 956)
[M::mem_pestat] mean and std.dev: (344.23, 167.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1205)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 447, 623)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1401)
[M::mem_pestat] mean and std.dev: (404.27, 239.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1790)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682006 sequences (100000015 bp) in 2.613 CPU sec, 2.773 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 277882, 10, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 298, 378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 868)
[M::mem_pestat] mean and std.dev: (247.61, 124.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1113)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 327, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 955)
[M::mem_pestat] mean and std.dev: (346.12, 167.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1203)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 579, 582)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1204)
[M::mem_pestat] mean and std.dev: (464.44, 184.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1515)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 262, 497)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1187)
[M::mem_pestat] mean and std.dev: (308.34, 216.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1532)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682008 sequences (100000270 bp) in 1.991 CPU sec, 2.004 real sec...
[M::mem_process_seqs] Processed 682504 reads in 184.740 CPU sec, 5.910 real sec
sorting block 48, #reads = 1069251 mem = 536877262 peak = 955056128
[M::mem_process_seqs] Processed 682014 reads in 127.003 CPU sec, 4.066 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 278111, 25, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 284, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 991)
[M::mem_pestat] mean and std.dev: (322.74, 188.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1263)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 326, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 952)
[M::mem_pestat] mean and std.dev: (345.73, 167.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1199)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (591, 771, 3427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9099)
[M::mem_pestat] mean and std.dev: (2096.64, 2669.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12774)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 301, 789)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1969)
[M::mem_pestat] mean and std.dev: (418.79, 369.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2559)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 49, #reads = 1070684 mem = 536879403 peak = 1023766528
[M::process] read 681766 sequences (100000258 bp) in 2.984 CPU sec, 3.189 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 278051, 5, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 509, 1701)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4647)
[M::mem_pestat] mean and std.dev: (690.35, 848.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6120)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 325, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 946)
[M::mem_pestat] mean and std.dev: (344.67, 166.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1191)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 277, 488)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1046)
[M::mem_pestat] mean and std.dev: (312.89, 157.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1325)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682116 sequences (100000227 bp) in 1.872 CPU sec, 1.902 real sec...
[M::mem_process_seqs] Processed 682006 reads in 188.136 CPU sec, 6.018 real sec
[M::mem_process_seqs] Processed 682008 reads in 127.110 CPU sec, 4.103 real sec
sorting block 50, #reads = 1069455 mem = 536877917 peak = 1023766528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 277688, 12, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 262, 507)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1059)
[M::mem_pestat] mean and std.dev: (323.07, 176.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1335)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 325, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 951)
[M::mem_pestat] mean and std.dev: (344.57, 167.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1198)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (304, 493, 1118)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2746)
[M::mem_pestat] mean and std.dev: (601.82, 547.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3560)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 262, 606)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1508)
[M::mem_pestat] mean and std.dev: (398.35, 379.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1959)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682302 sequences (100000071 bp) in 2.642 CPU sec, 2.935 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 278031, 18, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (255, 350, 488)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 954)
[M::mem_pestat] mean and std.dev: (375.32, 223.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1270)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 322, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 941)
[M::mem_pestat] mean and std.dev: (342.22, 166.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1185)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 750, 1591)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4379)
[M::mem_pestat] mean and std.dev: (563.93, 543.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5773)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 361, 479)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1029)
[M::mem_pestat] mean and std.dev: (325.43, 173.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1304)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682214 sequences (100000170 bp) in 1.949 CPU sec, 2.007 real sec...
[M::mem_process_seqs] Processed 681766 reads in 191.669 CPU sec, 6.182 real sec
[M::mem_process_seqs] Processed 682116 reads in 131.671 CPU sec, 4.230 real sec
sorting block 51, #reads = 1069342 mem = 536879979 peak = 1023766528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 277876, 9, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 301, 383)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (281.59, 111.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 827)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 323, 451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 935)
[M::mem_pestat] mean and std.dev: (341.96, 165.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1177)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 313, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1058)
[M::mem_pestat] mean and std.dev: (334.91, 237.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1356)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683312 sequences (100000213 bp) in 3.172 CPU sec, 3.433 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 277795, 14, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 323, 480)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1092)
[M::mem_pestat] mean and std.dev: (289.05, 156.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1398)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 322, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 938)
[M::mem_pestat] mean and std.dev: (341.53, 165.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1181)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (861, 1391, 2338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5292)
[M::mem_pestat] mean and std.dev: (1566.93, 744.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6769)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 393, 460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 890)
[M::mem_pestat] mean and std.dev: (324.93, 107.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1105)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682302 reads in 188.996 CPU sec, 6.053 real sec
[M::process] read 682420 sequences (100000216 bp) in 2.118 CPU sec, 2.154 real sec...
sorting block 52, #reads = 1069135 mem = 536878749 peak = 1023766528
[M::mem_process_seqs] Processed 682214 reads in 129.807 CPU sec, 4.169 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 278469, 10, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 319, 602)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1368)
[M::mem_pestat] mean and std.dev: (380.05, 247.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1751)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 315, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 925)
[M::mem_pestat] mean and std.dev: (335.80, 163.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1165)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (431, 2720, 2822)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7604)
[M::mem_pestat] mean and std.dev: (2166.80, 2001.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10172)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 351, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 866)
[M::mem_pestat] mean and std.dev: (327.62, 143.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1080)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682068 sequences (100000198 bp) in 2.721 CPU sec, 2.938 real sec...
sorting block 53, #reads = 1069357 mem = 536880888 peak = 1023766528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 278004, 11, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 245, 421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 897)
[M::mem_pestat] mean and std.dev: (296.96, 191.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1135)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 319, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 930)
[M::mem_pestat] mean and std.dev: (339.24, 164.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1171)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (908, 1054, 2543)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5813)
[M::mem_pestat] mean and std.dev: (1624.82, 1223.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7448)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 271, 892)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2270)
[M::mem_pestat] mean and std.dev: (438.65, 411.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2959)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683312 reads in 195.936 CPU sec, 6.322 real sec
[M::process] read 682240 sequences (100000090 bp) in 2.004 CPU sec, 2.075 real sec...
[M::mem_process_seqs] Processed 682420 reads in 138.527 CPU sec, 4.511 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 278300, 1, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 299, 510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1190)
[M::mem_pestat] mean and std.dev: (340.96, 256.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1530)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 322, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 939)
[M::mem_pestat] mean and std.dev: (342.40, 166.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1182)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 236, 941)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2439)
[M::mem_pestat] mean and std.dev: (428.79, 453.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3188)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 54, #reads = 1067408 mem = 536882084 peak = 1023766528
[M::process] read 681896 sequences (100000245 bp) in 2.697 CPU sec, 2.949 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 278198, 11, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 286, 433)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 901)
[M::mem_pestat] mean and std.dev: (306.62, 147.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1135)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 323, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 944)
[M::mem_pestat] mean and std.dev: (343.23, 167.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1189)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (376, 837, 2407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6469)
[M::mem_pestat] mean and std.dev: (1284.36, 1312.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8500)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (124, 150, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 643)
[M::mem_pestat] mean and std.dev: (182.09, 75.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 816)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682068 reads in 187.851 CPU sec, 6.151 real sec
[M::mem_process_seqs] Processed 682240 reads in 128.520 CPU sec, 4.163 real sec
[M::process] read 681886 sequences (100000001 bp) in 2.152 CPU sec, 2.396 real sec...
sorting block 55, #reads = 1069029 mem = 536880632 peak = 1023766528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 277745, 17, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 483, 971)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2457)
[M::mem_pestat] mean and std.dev: (541.70, 398.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3200)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 323, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 945)
[M::mem_pestat] mean and std.dev: (343.98, 167.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1190)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (460, 736, 1677)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4111)
[M::mem_pestat] mean and std.dev: (849.50, 831.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5328)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 339, 534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1210)
[M::mem_pestat] mean and std.dev: (290.89, 130.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1548)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681666 sequences (100000261 bp) in 3.014 CPU sec, 3.249 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 277985, 12, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 241, 535)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1281)
[M::mem_pestat] mean and std.dev: (281.59, 195.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1654)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 324, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 939)
[M::mem_pestat] mean and std.dev: (343.23, 166.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1182)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (410, 1344, 1695)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4265)
[M::mem_pestat] mean and std.dev: (1070.17, 724.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5550)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 296, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 964)
[M::mem_pestat] mean and std.dev: (311.08, 144.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1220)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681896 reads in 193.130 CPU sec, 6.256 real sec
[M::process] read 681702 sequences (100000082 bp) in 2.040 CPU sec, 2.223 real sec...
[M::mem_process_seqs] Processed 681886 reads in 132.907 CPU sec, 4.356 real sec
sorting block 56, #reads = 1069142 mem = 536877605 peak = 1023766528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 278221, 14, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 324, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1019)
[M::mem_pestat] mean and std.dev: (342.71, 248.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1337)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 323, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 942)
[M::mem_pestat] mean and std.dev: (343.37, 166.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1186)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (845, 845, 1463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2699)
[M::mem_pestat] mean and std.dev: (784.82, 294.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3317)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 347, 805)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1931)
[M::mem_pestat] mean and std.dev: (517.75, 425.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2494)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681618 sequences (100000125 bp) in 2.816 CPU sec, 3.149 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 277731, 15, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 228, 414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 976)
[M::mem_pestat] mean and std.dev: (283.92, 185.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1257)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 324, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 940)
[M::mem_pestat] mean and std.dev: (344.01, 166.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1183)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (952, 1029, 2286)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4954)
[M::mem_pestat] mean and std.dev: (1741.80, 1604.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8162)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 351, 389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 783)
[M::mem_pestat] mean and std.dev: (294.48, 96.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 980)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681666 reads in 184.680 CPU sec, 6.140 real sec
[M::process] read 681724 sequences (100000083 bp) in 2.180 CPU sec, 2.196 real sec...
sorting block 57, #reads = 1069447 mem = 536879063 peak = 1023766528
[M::mem_process_seqs] Processed 681702 reads in 126.369 CPU sec, 4.007 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 277949, 11, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 490, 1245)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3363)
[M::mem_pestat] mean and std.dev: (611.00, 597.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4422)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 326, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 938)
[M::mem_pestat] mean and std.dev: (345.03, 166.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1180)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (646, 804, 1823)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4177)
[M::mem_pestat] mean and std.dev: (979.40, 769.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5354)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (258, 447, 479)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 921)
[M::mem_pestat] mean and std.dev: (349.97, 167.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1142)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 58, #reads = 1068151 mem = 536877314 peak = 1023766528
[M::process] read 681204 sequences (100000231 bp) in 2.700 CPU sec, 2.954 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 278119, 10, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 333, 583)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1349)
[M::mem_pestat] mean and std.dev: (424.17, 346.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1812)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 323, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 937)
[M::mem_pestat] mean and std.dev: (343.50, 166.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1179)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (121, 615, 1048)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2902)
[M::mem_pestat] mean and std.dev: (478.75, 369.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3829)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 273, 391)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 739)
[M::mem_pestat] mean and std.dev: (293.26, 124.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 913)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681618 reads in 183.262 CPU sec, 5.931 real sec
[M::process] read 681492 sequences (100000250 bp) in 1.974 CPU sec, 2.052 real sec...
[M::mem_process_seqs] Processed 681724 reads in 127.015 CPU sec, 4.084 real sec
sorting block 59, #reads = 1068326 mem = 536878948 peak = 1023766528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 277554, 17, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 299, 634)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1494)
[M::mem_pestat] mean and std.dev: (337.42, 174.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1924)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 327, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 951)
[M::mem_pestat] mean and std.dev: (347.55, 168.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1197)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (291, 757, 3467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9819)
[M::mem_pestat] mean and std.dev: (1471.71, 1833.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12995)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 242, 746)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1832)
[M::mem_pestat] mean and std.dev: (497.68, 516.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2563)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 684222 sequences (100000010 bp) in 2.699 CPU sec, 2.993 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 278404, 6, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 323, 525)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1205)
[M::mem_pestat] mean and std.dev: (341.42, 201.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1545)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 327, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 946)
[M::mem_pestat] mean and std.dev: (347.18, 167.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1190)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 414, 946)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2414)
[M::mem_pestat] mean and std.dev: (506.49, 343.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3148)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681204 reads in 190.268 CPU sec, 6.191 real sec
[M::process] read 683566 sequences (100000144 bp) in 2.080 CPU sec, 2.094 real sec...
[M::mem_process_seqs] Processed 681492 reads in 132.749 CPU sec, 4.314 real sec
sorting block 60, #reads = 1068946 mem = 536878490 peak = 1023766528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 278469, 12, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 303, 474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1044)
[M::mem_pestat] mean and std.dev: (356.62, 216.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1329)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 313, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 925)
[M::mem_pestat] mean and std.dev: (333.65, 163.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1166)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (915, 1977, 4690)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12240)
[M::mem_pestat] mean and std.dev: (2109.33, 1595.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16015)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 385, 1068)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2734)
[M::mem_pestat] mean and std.dev: (561.72, 508.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3567)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682740 sequences (100000297 bp) in 2.578 CPU sec, 3.046 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 278348, 17, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 384, 793)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1901)
[M::mem_pestat] mean and std.dev: (488.06, 379.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2455)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 318, 451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 943)
[M::mem_pestat] mean and std.dev: (339.16, 166.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1189)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (434, 609, 3306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9050)
[M::mem_pestat] mean and std.dev: (1847.47, 1887.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11922)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 337, 541)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1251)
[M::mem_pestat] mean and std.dev: (322.65, 186.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1606)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682612 sequences (100000117 bp) in 2.082 CPU sec, 2.152 real sec...
[M::mem_process_seqs] Processed 684222 reads in 192.970 CPU sec, 6.193 real sec
sorting block 61, #reads = 1067917 mem = 536879075 peak = 1023766528
[M::mem_process_seqs] Processed 683566 reads in 130.373 CPU sec, 4.163 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 277803, 27, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 231, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1058)
[M::mem_pestat] mean and std.dev: (267.17, 195.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1364)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 323, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 953)
[M::mem_pestat] mean and std.dev: (343.50, 167.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1201)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (346, 1231, 1774)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4630)
[M::mem_pestat] mean and std.dev: (982.93, 706.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6058)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 272, 719)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1739)
[M::mem_pestat] mean and std.dev: (436.57, 343.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2249)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682228 sequences (100000128 bp) in 2.770 CPU sec, 3.002 real sec...
sorting block 62, #reads = 1070794 mem = 536881447 peak = 1023766528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 278151, 13, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 312, 507)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1143)
[M::mem_pestat] mean and std.dev: (317.38, 193.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1461)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 326, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 957)
[M::mem_pestat] mean and std.dev: (345.76, 168.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1206)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (308, 975, 1970)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5294)
[M::mem_pestat] mean and std.dev: (1006.15, 831.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6956)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 328, 542)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1186)
[M::mem_pestat] mean and std.dev: (361.78, 198.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1508)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681880 sequences (100000090 bp) in 2.034 CPU sec, 2.103 real sec...
[M::mem_process_seqs] Processed 682740 reads in 191.202 CPU sec, 6.140 real sec
[M::mem_process_seqs] Processed 682612 reads in 131.026 CPU sec, 4.197 real sec
sorting block 63, #reads = 1070143 mem = 536881471 peak = 1023766528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 278396, 13, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 265, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 610)
[M::mem_pestat] mean and std.dev: (277.57, 65.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 733)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 330, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 973)
[M::mem_pestat] mean and std.dev: (349.07, 170.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1227)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 319, 1342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3638)
[M::mem_pestat] mean and std.dev: (546.85, 483.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4786)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (287, 492, 885)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2081)
[M::mem_pestat] mean and std.dev: (598.07, 431.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2679)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682120 sequences (100000168 bp) in 3.140 CPU sec, 3.313 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 277922, 16, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 315, 961)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2453)
[M::mem_pestat] mean and std.dev: (592.66, 665.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3253)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 331, 464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 968)
[M::mem_pestat] mean and std.dev: (349.40, 169.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1220)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (399, 516, 1349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3249)
[M::mem_pestat] mean and std.dev: (714.07, 407.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4199)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 381, 560)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1194)
[M::mem_pestat] mean and std.dev: (430.15, 268.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1511)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681358 sequences (100000036 bp) in 2.050 CPU sec, 2.047 real sec...
[M::mem_process_seqs] Processed 682228 reads in 182.543 CPU sec, 5.802 real sec
[M::mem_process_seqs] Processed 681880 reads in 123.679 CPU sec, 3.908 real sec
sorting block 64, #reads = 1071211 mem = 536877458 peak = 1023766528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 277817, 8, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 335, 490)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1006)
[M::mem_pestat] mean and std.dev: (364.12, 188.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1264)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 330, 464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 968)
[M::mem_pestat] mean and std.dev: (349.39, 170.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1220)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 375, 616)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1386)
[M::mem_pestat] mean and std.dev: (398.62, 259.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1771)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680892 sequences (100000199 bp) in 2.765 CPU sec, 2.940 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 277264, 4, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 337, 589)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1465)
[M::mem_pestat] mean and std.dev: (315.89, 193.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1903)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 335, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 974)
[M::mem_pestat] mean and std.dev: (352.77, 170.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1227)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 292, 676)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1572)
[M::mem_pestat] mean and std.dev: (416.36, 299.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2020)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680820 sequences (100000230 bp) in 1.774 CPU sec, 1.788 real sec...
[M::mem_process_seqs] Processed 682120 reads in 180.041 CPU sec, 5.725 real sec
sorting block 65, #reads = 1071024 mem = 536881131 peak = 1023766528
[M::process] read 680804 sequences (100000100 bp) in 2.188 CPU sec, 2.190 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 277320, 7, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 222, 684)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1704)
[M::mem_pestat] mean and std.dev: (315.45, 311.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2214)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 337, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 979)
[M::mem_pestat] mean and std.dev: (354.94, 170.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1233)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 247, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 686)
[M::mem_pestat] mean and std.dev: (267.46, 104.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 848)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680892 reads in 109.671 CPU sec, 3.766 real sec
[M::mem_process_seqs] Processed 681358 reads in 265.021 CPU sec, 8.715 real sec
sorting block 66, #reads = 1070012 mem = 536878089 peak = 1023766528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 277677, 11, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 320, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 925)
[M::mem_pestat] mean and std.dev: (268.42, 117.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1170)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 340, 475)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 987)
[M::mem_pestat] mean and std.dev: (357.30, 171.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1243)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (764, 767, 1154)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1934)
[M::mem_pestat] mean and std.dev: (692.89, 315.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2324)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 335, 671)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1619)
[M::mem_pestat] mean and std.dev: (376.79, 218.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2093)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681952 sequences (100000270 bp) in 2.611 CPU sec, 2.808 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 277965, 5, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 378, 541)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1235)
[M::mem_pestat] mean and std.dev: (356.48, 219.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1582)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 340, 475)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 987)
[M::mem_pestat] mean and std.dev: (357.69, 172.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1243)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (323, 344, 649)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1301)
[M::mem_pestat] mean and std.dev: (449.42, 294.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1627)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680820 reads in 205.467 CPU sec, 6.535 real sec
[M::process] read 682538 sequences (100000027 bp) in 1.871 CPU sec, 1.881 real sec...
[M::mem_process_seqs] Processed 680804 reads in 125.670 CPU sec, 4.226 real sec
sorting block 67, #reads = 1070642 mem = 536887042 peak = 1023766528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 277763, 9, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 272, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 896)
[M::mem_pestat] mean and std.dev: (307.50, 129.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1125)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 330, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 974)
[M::mem_pestat] mean and std.dev: (350.03, 170.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1228)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (299, 379, 662)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1388)
[M::mem_pestat] mean and std.dev: (409.76, 229.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1751)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681808 sequences (100000026 bp) in 2.902 CPU sec, 3.109 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 278427, 29, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 276, 739)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1877)
[M::mem_pestat] mean and std.dev: (329.92, 241.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2446)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 324, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 959)
[M::mem_pestat] mean and std.dev: (345.63, 169.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1209)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (548, 899, 3665)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9899)
[M::mem_pestat] mean and std.dev: (1697.10, 1900.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13016)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 352, 522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1146)
[M::mem_pestat] mean and std.dev: (338.19, 162.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1458)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682034 sequences (100000088 bp) in 2.023 CPU sec, 2.037 real sec...
[M::mem_process_seqs] Processed 681952 reads in 195.089 CPU sec, 6.444 real sec
sorting block 68, #reads = 1069921 mem = 536880082 peak = 1023766528
[M::mem_process_seqs] Processed 682538 reads in 129.139 CPU sec, 4.106 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 277614, 12, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 373, 501)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1089)
[M::mem_pestat] mean and std.dev: (363.20, 199.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1383)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 329, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 967)
[M::mem_pestat] mean and std.dev: (348.27, 169.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1219)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (483, 660, 2970)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7944)
[M::mem_pestat] mean and std.dev: (1187.55, 1038.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10431)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 206, 562)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1328)
[M::mem_pestat] mean and std.dev: (365.26, 312.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1711)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 69, #reads = 1070579 mem = 536878646 peak = 1036025856
[M::process] read 682000 sequences (100000176 bp) in 2.728 CPU sec, 2.876 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 277787, 15, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 219, 528)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1176)
[M::mem_pestat] mean and std.dev: (327.21, 211.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1500)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 327, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 961)
[M::mem_pestat] mean and std.dev: (346.99, 168.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1211)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 431, 716)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1800)
[M::mem_pestat] mean and std.dev: (465.80, 381.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2342)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 349, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1051)
[M::mem_pestat] mean and std.dev: (265.62, 121.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1352)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681874 sequences (100000205 bp) in 2.146 CPU sec, 2.173 real sec...
[M::mem_process_seqs] Processed 681808 reads in 193.682 CPU sec, 6.178 real sec
[M::mem_process_seqs] Processed 682034 reads in 131.330 CPU sec, 4.180 real sec
sorting block 70, #reads = 1069297 mem = 536878415 peak = 1036025856
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 278249, 7, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (125, 173, 402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 956)
[M::mem_pestat] mean and std.dev: (220.65, 122.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1233)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 325, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 954)
[M::mem_pestat] mean and std.dev: (344.88, 167.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1202)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (280, 420, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 817)
[M::mem_pestat] mean and std.dev: (329.11, 119.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 996)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682498 sequences (100000066 bp) in 3.163 CPU sec, 3.345 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 277989, 10, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 470, 715)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1671)
[M::mem_pestat] mean and std.dev: (513.00, 391.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2149)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 324, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 951)
[M::mem_pestat] mean and std.dev: (344.19, 166.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1198)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (334, 684, 722)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1498)
[M::mem_pestat] mean and std.dev: (488.90, 252.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1886)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 324, 535)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1247)
[M::mem_pestat] mean and std.dev: (382.19, 206.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1603)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682258 sequences (100000274 bp) in 2.037 CPU sec, 2.043 real sec...
[M::mem_process_seqs] Processed 682000 reads in 193.327 CPU sec, 6.149 real sec
[M::mem_process_seqs] Processed 681874 reads in 131.200 CPU sec, 4.163 real sec
sorting block 71, #reads = 1070099 mem = 536879819 peak = 1036025856
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 278272, 12, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 340, 1043)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2711)
[M::mem_pestat] mean and std.dev: (497.30, 397.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3545)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 322, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 947)
[M::mem_pestat] mean and std.dev: (342.59, 166.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1193)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (838, 988, 6081)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 16567)
[M::mem_pestat] mean and std.dev: (2201.83, 2279.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 21810)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 289, 495)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1085)
[M::mem_pestat] mean and std.dev: (284.66, 130.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1380)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682486 sequences (100000241 bp) in 2.872 CPU sec, 3.056 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 277796, 10, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 378, 671)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1603)
[M::mem_pestat] mean and std.dev: (430.90, 279.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2069)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 321, 451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 935)
[M::mem_pestat] mean and std.dev: (340.69, 164.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1177)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 319, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1106)
[M::mem_pestat] mean and std.dev: (294.67, 227.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1425)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 260, 610)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1428)
[M::mem_pestat] mean and std.dev: (414.14, 323.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1837)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682148 sequences (100000247 bp) in 2.106 CPU sec, 2.112 real sec...
[M::mem_process_seqs] Processed 682498 reads in 195.309 CPU sec, 6.208 real sec
sorting block 72, #reads = 1068946 mem = 536877907 peak = 1036025856
[M::mem_process_seqs] Processed 682258 reads in 131.722 CPU sec, 4.173 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 278294, 7, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 282, 690)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1698)
[M::mem_pestat] mean and std.dev: (416.86, 326.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2202)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 320, 451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 937)
[M::mem_pestat] mean and std.dev: (340.29, 164.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1180)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 332, 618)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1352)
[M::mem_pestat] mean and std.dev: (388.22, 229.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1719)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681984 sequences (100000064 bp) in 3.185 CPU sec, 3.352 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 277562, 12, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 295, 783)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2009)
[M::mem_pestat] mean and std.dev: (431.58, 391.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2622)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 320, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 934)
[M::mem_pestat] mean and std.dev: (339.77, 163.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1176)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (759, 2574, 2574)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6204)
[M::mem_pestat] mean and std.dev: (1736.67, 1248.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8019)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 328, 673)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1667)
[M::mem_pestat] mean and std.dev: (402.76, 360.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2164)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681914 sequences (100000261 bp) in 2.060 CPU sec, 2.066 real sec...
[M::mem_process_seqs] Processed 682486 reads in 188.609 CPU sec, 5.986 real sec
sorting block 73, #reads = 1069522 mem = 536882837 peak = 1036025856
[M::mem_process_seqs] Processed 682148 reads in 127.481 CPU sec, 4.038 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 277603, 8, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 261, 420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 874)
[M::mem_pestat] mean and std.dev: (300.32, 148.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1101)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 323, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 936)
[M::mem_pestat] mean and std.dev: (341.74, 164.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1178)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 230, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (233.74, 104.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 851)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 74, #reads = 1068846 mem = 536876929 peak = 1070669824
[M::process] read 682288 sequences (100000178 bp) in 2.826 CPU sec, 2.997 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 277390, 10, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 281, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 565)
[M::mem_pestat] mean and std.dev: (258.93, 102.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 688)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 323, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 938)
[M::mem_pestat] mean and std.dev: (342.12, 165.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1181)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 802, 1625)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4391)
[M::mem_pestat] mean and std.dev: (762.00, 645.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5774)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 297, 563)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1265)
[M::mem_pestat] mean and std.dev: (357.89, 184.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1616)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682524 sequences (100000271 bp) in 1.827 CPU sec, 1.832 real sec...
[M::mem_process_seqs] Processed 681984 reads in 189.547 CPU sec, 6.037 real sec
[M::mem_process_seqs] Processed 681914 reads in 127.621 CPU sec, 4.050 real sec
sorting block 75, #reads = 1068815 mem = 536878872 peak = 1070669824
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 277943, 3, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 298, 515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1169)
[M::mem_pestat] mean and std.dev: (311.41, 169.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1496)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 321, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 944)
[M::mem_pestat] mean and std.dev: (342.02, 166.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1189)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 325, 499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1107)
[M::mem_pestat] mean and std.dev: (278.35, 130.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1411)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682214 sequences (100000146 bp) in 3.129 CPU sec, 3.275 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 277404, 16, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 304, 398)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 792)
[M::mem_pestat] mean and std.dev: (268.03, 125.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 989)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 320, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 946)
[M::mem_pestat] mean and std.dev: (341.65, 166.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1192)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (295, 501, 1633)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4309)
[M::mem_pestat] mean and std.dev: (836.50, 874.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5647)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 323, 382)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 734)
[M::mem_pestat] mean and std.dev: (321.06, 165.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 982)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681986 sequences (100000267 bp) in 1.959 CPU sec, 1.964 real sec...
[M::mem_process_seqs] Processed 682288 reads in 193.263 CPU sec, 6.141 real sec
[M::mem_process_seqs] Processed 682524 reads in 130.756 CPU sec, 4.143 real sec
sorting block 76, #reads = 1068510 mem = 536881857 peak = 1070669824
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 277932, 10, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 324, 523)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1223)
[M::mem_pestat] mean and std.dev: (295.62, 132.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1573)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 319, 451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 937)
[M::mem_pestat] mean and std.dev: (340.52, 165.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1180)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 210, 515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1269)
[M::mem_pestat] mean and std.dev: (299.00, 350.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1702)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 306, 1008)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2576)
[M::mem_pestat] mean and std.dev: (647.38, 695.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3430)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681596 sequences (100000233 bp) in 2.689 CPU sec, 2.843 real sec...
[M::process] read 681238 sequences (100000071 bp) in 1.990 CPU sec, 1.996 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 277840, 5, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 332, 378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 656)
[M::mem_pestat] mean and std.dev: (297.47, 110.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 795)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 323, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 939)
[M::mem_pestat] mean and std.dev: (342.21, 165.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1182)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (324, 481, 1562)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4038)
[M::mem_pestat] mean and std.dev: (1086.91, 1153.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5699)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682214 reads in 191.020 CPU sec, 6.081 real sec
sorting block 77, #reads = 1068573 mem = 536879498 peak = 1070669824
[M::mem_process_seqs] Processed 681986 reads in 129.432 CPU sec, 4.382 real sec
sorting block 78, #reads = 1069616 mem = 536882426 peak = 1070669824
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 277613, 18, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 373, 1520)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4072)
[M::mem_pestat] mean and std.dev: (870.44, 1081.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5348)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 325, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 938)
[M::mem_pestat] mean and std.dev: (343.87, 164.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1180)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 301, 1181)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3135)
[M::mem_pestat] mean and std.dev: (666.44, 534.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4112)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 350, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 887)
[M::mem_pestat] mean and std.dev: (336.18, 156.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1113)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681260 sequences (100000079 bp) in 2.872 CPU sec, 3.024 real sec...
[M::process] read 681488 sequences (100000089 bp) in 1.980 CPU sec, 1.975 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 277874, 17, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 255, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 944)
[M::mem_pestat] mean and std.dev: (282.34, 154.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1195)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 327, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 942)
[M::mem_pestat] mean and std.dev: (345.36, 165.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1185)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 453, 1054)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2770)
[M::mem_pestat] mean and std.dev: (516.12, 428.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3628)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 312, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 984)
[M::mem_pestat] mean and std.dev: (324.83, 143.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1245)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681596 reads in 191.844 CPU sec, 6.357 real sec
[M::mem_process_seqs] Processed 681238 reads in 125.796 CPU sec, 3.986 real sec
sorting block 79, #reads = 1069039 mem = 536880628 peak = 1070669824
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 277619, 14, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 239, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 739)
[M::mem_pestat] mean and std.dev: (240.13, 119.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 931)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 329, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 946)
[M::mem_pestat] mean and std.dev: (347.10, 166.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1190)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (927, 1823, 3230)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7836)
[M::mem_pestat] mean and std.dev: (1969.64, 1385.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10139)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 384, 823)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2029)
[M::mem_pestat] mean and std.dev: (449.88, 373.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2632)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681206 sequences (100000104 bp) in 2.838 CPU sec, 2.995 real sec...
[M::process] read 684910 sequences (100000109 bp) in 1.735 CPU sec, 1.741 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 277824, 12, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 414, 557)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1259)
[M::mem_pestat] mean and std.dev: (378.14, 205.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1610)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 327, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 945)
[M::mem_pestat] mean and std.dev: (345.53, 165.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1189)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (546, 1181, 1181)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2451)
[M::mem_pestat] mean and std.dev: (862.42, 547.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3086)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (268, 403, 591)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1237)
[M::mem_pestat] mean and std.dev: (362.10, 161.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1560)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681260 reads in 185.656 CPU sec, 5.902 real sec
[M::mem_process_seqs] Processed 681488 reads in 125.425 CPU sec, 3.983 real sec
sorting block 80, #reads = 1068066 mem = 536888059 peak = 1070669824
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 278022, 16, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 288, 616)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1396)
[M::mem_pestat] mean and std.dev: (341.03, 209.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1786)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 330, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 953)
[M::mem_pestat] mean and std.dev: (348.86, 167.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1199)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (305, 505, 543)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1019)
[M::mem_pestat] mean and std.dev: (416.20, 209.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1257)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 306, 485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 999)
[M::mem_pestat] mean and std.dev: (313.48, 172.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1256)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 688756 sequences (100000007 bp) in 2.941 CPU sec, 3.074 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 279461, 10, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 346, 692)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1630)
[M::mem_pestat] mean and std.dev: (437.74, 334.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2099)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 687844 sequences (100000090 bp) in 1.950 CPU sec, 1.957 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (199, 309, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 931)
[M::mem_pestat] mean and std.dev: (331.93, 164.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1175)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (291, 440, 515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 963)
[M::mem_pestat] mean and std.dev: (365.20, 214.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1224)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (277, 379, 604)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1258)
[M::mem_pestat] mean and std.dev: (405.36, 204.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1585)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681206 reads in 192.177 CPU sec, 6.102 real sec
sorting block 81, #reads = 1068065 mem = 536878600 peak = 1070669824
[M::mem_process_seqs] Processed 684910 reads in 133.188 CPU sec, 4.222 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 281204, 7, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 343, 636)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1534)
[M::mem_pestat] mean and std.dev: (421.19, 307.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1983)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 288, 425)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 905)
[M::mem_pestat] mean and std.dev: (316.28, 161.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1145)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (355, 789, 1045)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2425)
[M::mem_pestat] mean and std.dev: (644.41, 394.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3115)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 687328 sequences (100000145 bp) in 2.846 CPU sec, 2.980 real sec...
[M::process] read 687644 sequences (100000214 bp) in 2.050 CPU sec, 2.049 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 280259, 20, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 238, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 994)
[M::mem_pestat] mean and std.dev: (320.54, 213.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1273)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 294, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 917)
[M::mem_pestat] mean and std.dev: (320.72, 163.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1160)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (539, 577, 1557)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3593)
[M::mem_pestat] mean and std.dev: (1067.05, 963.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4923)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 323, 888)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2288)
[M::mem_pestat] mean and std.dev: (565.50, 460.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2988)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 688756 reads in 201.848 CPU sec, 6.419 real sec
sorting block 82, #reads = 1068340 mem = 536878446 peak = 1070669824
[M::mem_process_seqs] Processed 687844 reads in 133.784 CPU sec, 4.244 real sec
sorting block 83, #reads = 1070146 mem = 536879779 peak = 1072492544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 280463, 10, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 341, 410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 840)
[M::mem_pestat] mean and std.dev: (276.42, 109.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1055)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 296, 433)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 919)
[M::mem_pestat] mean and std.dev: (322.15, 162.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1162)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1254, 1254, 1262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1238, 1278)
[M::mem_pestat] mean and std.dev: (1255.50, 2.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1230, 1286)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 344, 657)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1495)
[M::mem_pestat] mean and std.dev: (386.52, 274.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1914)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 686638 sequences (100000041 bp) in 3.259 CPU sec, 3.392 real sec...
[M::process] read 685402 sequences (100000096 bp) in 2.041 CPU sec, 2.041 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 280520, 19, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 263, 375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 721)
[M::mem_pestat] mean and std.dev: (262.06, 90.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 894)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 294, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 912)
[M::mem_pestat] mean and std.dev: (319.71, 160.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1153)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (678, 1246, 2340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5664)
[M::mem_pestat] mean and std.dev: (1318.32, 1069.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7326)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 282, 1284)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3550)
[M::mem_pestat] mean and std.dev: (662.96, 601.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4683)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 687328 reads in 203.007 CPU sec, 6.438 real sec
[M::mem_process_seqs] Processed 687644 reads in 136.208 CPU sec, 4.320 real sec
sorting block 84, #reads = 1068714 mem = 536878304 peak = 1072492544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 279851, 7, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 251, 423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 959)
[M::mem_pestat] mean and std.dev: (241.31, 121.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1227)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 300, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 924)
[M::mem_pestat] mean and std.dev: (324.15, 161.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1168)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 267, 583)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1329)
[M::mem_pestat] mean and std.dev: (373.35, 225.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1702)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 684704 sequences (100000026 bp) in 2.853 CPU sec, 2.986 real sec...
[M::process] read 684974 sequences (100000008 bp) in 2.059 CPU sec, 2.058 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 279577, 12, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 501, 920)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2428)
[M::mem_pestat] mean and std.dev: (581.72, 572.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3182)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 307, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 935)
[M::mem_pestat] mean and std.dev: (329.81, 162.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1181)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (37, 226, 451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1279)
[M::mem_pestat] mean and std.dev: (196.17, 164.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1693)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 263, 531)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1201)
[M::mem_pestat] mean and std.dev: (318.69, 204.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1536)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 686638 reads in 201.354 CPU sec, 6.400 real sec
[M::mem_process_seqs] Processed 685402 reads in 136.080 CPU sec, 4.314 real sec
sorting block 85, #reads = 1067131 mem = 536880221 peak = 1072492544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 279805, 10, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 355, 1263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3419)
[M::mem_pestat] mean and std.dev: (726.35, 835.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4497)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 313, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 941)
[M::mem_pestat] mean and std.dev: (333.26, 162.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1188)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1028, 1693, 2433)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5243)
[M::mem_pestat] mean and std.dev: (1737.60, 1205.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6648)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 322, 612)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1484)
[M::mem_pestat] mean and std.dev: (442.33, 355.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1920)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 684924 sequences (100000242 bp) in 2.950 CPU sec, 3.087 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 279345, 5, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (269, 349, 645)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1397)
[M::mem_pestat] mean and std.dev: (495.52, 390.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2057)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 313, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 949)
[M::mem_pestat] mean and std.dev: (334.07, 164.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1199)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 326, 380)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (11, 626)
[M::mem_pestat] mean and std.dev: (315.59, 89.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 749)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 686644 sequences (100000076 bp) in 2.160 CPU sec, 2.159 real sec...
[M::mem_process_seqs] Processed 684704 reads in 195.158 CPU sec, 6.192 real sec
sorting block 86, #reads = 1067075 mem = 536878041 peak = 1072492544
[M::mem_process_seqs] Processed 684974 reads in 131.241 CPU sec, 4.157 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 279247, 13, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (258, 465, 503)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 993)
[M::mem_pestat] mean and std.dev: (356.82, 142.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1238)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
sorting block 87, #reads = 1068067 mem = 536879600 peak = 1072492544
[M::mem_pestat] (25, 50, 75) percentile: (199, 313, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 940)
[M::mem_pestat] mean and std.dev: (332.78, 162.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1187)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1003, 1003, 1681)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3037)
[M::mem_pestat] mean and std.dev: (1205.15, 403.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3715)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 342, 531)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1151)
[M::mem_pestat] mean and std.dev: (342.06, 179.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1461)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 687116 sequences (100000121 bp) in 2.917 CPU sec, 3.046 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 281051, 9, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 310, 666)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1698)
[M::mem_pestat] mean and std.dev: (322.20, 243.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2214)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 300, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 907)
[M::mem_pestat] mean and std.dev: (322.34, 159.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1145)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 337, 742)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1736)
[M::mem_pestat] mean and std.dev: (448.19, 324.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2233)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 687236 sequences (100000170 bp) in 2.091 CPU sec, 2.099 real sec...
[M::mem_process_seqs] Processed 684924 reads in 201.335 CPU sec, 6.406 real sec
[M::mem_process_seqs] Processed 686644 reads in 137.355 CPU sec, 4.365 real sec
sorting block 88, #reads = 1068252 mem = 536878202 peak = 1072492544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 280246, 6, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (249, 310, 528)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1086)
[M::mem_pestat] mean and std.dev: (357.56, 192.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1365)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 296, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 910)
[M::mem_pestat] mean and std.dev: (319.98, 159.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1150)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 282, 410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 838)
[M::mem_pestat] mean and std.dev: (293.63, 126.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1052)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 687358 sequences (100000216 bp) in 2.953 CPU sec, 3.068 real sec...
[M::process] read 687566 sequences (100000064 bp) in 2.090 CPU sec, 2.091 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 280538, 9, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 288, 575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1303)
[M::mem_pestat] mean and std.dev: (334.21, 216.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1667)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 295, 428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 904)
[M::mem_pestat] mean and std.dev: (318.89, 158.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1142)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 526, 710)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1692)
[M::mem_pestat] mean and std.dev: (506.37, 339.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2183)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 687116 reads in 212.349 CPU sec, 6.770 real sec
[M::mem_process_seqs] Processed 687236 reads in 141.263 CPU sec, 4.479 real sec
sorting block 89, #reads = 1067383 mem = 536879346 peak = 1072492544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 280516, 17, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 375, 681)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1595)
[M::mem_pestat] mean and std.dev: (386.71, 245.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2052)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 295, 427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 901)
[M::mem_pestat] mean and std.dev: (318.71, 158.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1138)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (837, 1002, 2768)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6630)
[M::mem_pestat] mean and std.dev: (1392.56, 949.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8561)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 282, 705)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1757)
[M::mem_pestat] mean and std.dev: (313.11, 196.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2283)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 685670 sequences (100000128 bp) in 2.995 CPU sec, 3.119 real sec...
[M::process] read 685140 sequences (100000065 bp) in 2.090 CPU sec, 2.090 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 280088, 24, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 235, 525)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1245)
[M::mem_pestat] mean and std.dev: (280.55, 223.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1605)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 294, 426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 900)
[M::mem_pestat] mean and std.dev: (317.49, 157.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1137)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (573, 809, 837)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (45, 1365)
[M::mem_pestat] mean and std.dev: (690.57, 285.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1832)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 336, 521)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1121)
[M::mem_pestat] mean and std.dev: (331.52, 192.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1421)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 687358 reads in 217.575 CPU sec, 6.932 real sec
sorting block 90, #reads = 1065367 mem = 536879123 peak = 1072492544
[M::mem_process_seqs] Processed 687566 reads in 157.229 CPU sec, 5.024 real sec
sorting block 91, #reads = 1063639 mem = 536880872 peak = 1072492544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 279250, 6, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 332, 583)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1479)
[M::mem_pestat] mean and std.dev: (325.03, 206.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1927)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 303, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 918)
[M::mem_pestat] mean and std.dev: (325.61, 160.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1159)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (272, 537, 1318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3410)
[M::mem_pestat] mean and std.dev: (728.08, 676.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4456)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 684852 sequences (100000239 bp) in 2.944 CPU sec, 3.081 real sec...
[M::process] read 689534 sequences (100000155 bp) in 1.722 CPU sec, 1.733 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 279345, 6, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 328, 516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1100)
[M::mem_pestat] mean and std.dev: (338.35, 179.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1392)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 307, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 920)
[M::mem_pestat] mean and std.dev: (327.91, 160.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1161)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 249, 407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 843)
[M::mem_pestat] mean and std.dev: (243.81, 81.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1061)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 685670 reads in 211.932 CPU sec, 6.755 real sec
[M::mem_process_seqs] Processed 685140 reads in 149.500 CPU sec, 4.783 real sec
sorting block 92, #reads = 1063754 mem = 536878782 peak = 1072492544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 278894, 21, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 352, 510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1100)
[M::mem_pestat] mean and std.dev: (316.72, 175.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1395)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 308, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 921)
[M::mem_pestat] mean and std.dev: (328.74, 160.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1162)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (394, 1144, 2574)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6934)
[M::mem_pestat] mean and std.dev: (1682.29, 1655.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9114)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 288, 400)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 800)
[M::mem_pestat] mean and std.dev: (274.73, 117.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1000)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 686288 sequences (100000180 bp) in 2.923 CPU sec, 3.031 real sec...
[M::process] read 685840 sequences (100000007 bp) in 1.810 CPU sec, 1.805 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 280071, 20, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 329, 920)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2310)
[M::mem_pestat] mean and std.dev: (495.75, 446.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3005)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 285, 412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 868)
[M::mem_pestat] mean and std.dev: (308.20, 152.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1096)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (744, 2081, 2769)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6819)
[M::mem_pestat] mean and std.dev: (1775.72, 1443.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8844)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 279, 517)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1131)
[M::mem_pestat] mean and std.dev: (328.13, 202.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1438)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684852 reads in 217.288 CPU sec, 6.915 real sec
[M::mem_process_seqs] Processed 689534 reads in 156.113 CPU sec, 4.972 real sec
sorting block 93, #reads = 1065944 mem = 536884677 peak = 1072492544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 279821, 10, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 515, 741)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1901)
[M::mem_pestat] mean and std.dev: (456.59, 326.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2481)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 298, 428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 898)
[M::mem_pestat] mean and std.dev: (319.86, 156.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1133)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (263, 516, 837)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1985)
[M::mem_pestat] mean and std.dev: (509.89, 260.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2559)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 361, 727)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1769)
[M::mem_pestat] mean and std.dev: (426.61, 323.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2290)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 684620 sequences (100000247 bp) in 3.198 CPU sec, 3.322 real sec...
[M::process] read 684884 sequences (100000091 bp) in 2.040 CPU sec, 2.046 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 279269, 8, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 327, 758)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1898)
[M::mem_pestat] mean and std.dev: (522.49, 463.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2468)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 298, 425)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 887)
[M::mem_pestat] mean and std.dev: (319.27, 154.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1118)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 351, 789)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1875)
[M::mem_pestat] mean and std.dev: (493.96, 393.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2418)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 686288 reads in 218.996 CPU sec, 6.945 real sec
sorting block 94, #reads = 1055976 mem = 536884614 peak = 1072492544
[M::mem_process_seqs] Processed 685840 reads in 245.000 CPU sec, 7.793 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 278803, 14, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 316, 487)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1097)
[M::mem_pestat] mean and std.dev: (301.00, 196.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1402)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 307, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 919)
[M::mem_pestat] mean and std.dev: (328.29, 159.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1159)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (11, 128, 481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1421)
[M::mem_pestat] mean and std.dev: (231.69, 302.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1891)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (258, 339, 786)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1842)
[M::mem_pestat] mean and std.dev: (443.14, 354.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2370)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 684608 sequences (100000232 bp) in 3.236 CPU sec, 3.326 real sec...
[M::process] read 684338 sequences (100000034 bp) in 1.930 CPU sec, 1.928 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 278575, 6, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 267, 536)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1298)
[M::mem_pestat] mean and std.dev: (340.02, 261.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1679)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 306, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 918)
[M::mem_pestat] mean and std.dev: (327.59, 159.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1158)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 350, 879)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2197)
[M::mem_pestat] mean and std.dev: (508.32, 382.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2856)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684620 reads in 206.564 CPU sec, 6.553 real sec
sorting block 95, #reads = 1059270 mem = 536880598 peak = 1072492544
[M::process] read 684992 sequences (100000105 bp) in 2.132 CPU sec, 2.140 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 279184, 6, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 334, 420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 874)
[M::mem_pestat] mean and std.dev: (295.42, 146.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1101)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 308, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 928)
[M::mem_pestat] mean and std.dev: (330.09, 161.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1171)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 348, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 858)
[M::mem_pestat] mean and std.dev: (334.74, 128.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1061)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684608 reads in 118.390 CPU sec, 3.760 real sec
sorting block 96, #reads = 1061949 mem = 536889018 peak = 1072492544
[M::mem_process_seqs] Processed 684884 reads in 284.790 CPU sec, 9.057 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (17, 279071, 13, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 300, 1101)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2953)
[M::mem_pestat] mean and std.dev: (448.73, 376.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3879)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 309, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 929)
[M::mem_pestat] mean and std.dev: (331.37, 162.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1172)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (541, 895, 1573)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3637)
[M::mem_pestat] mean and std.dev: (769.08, 453.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4669)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 481, 551)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1173)
[M::mem_pestat] mean and std.dev: (386.21, 177.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1484)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 684256 sequences (100000138 bp) in 2.994 CPU sec, 3.151 real sec...
[M::process] read 691384 sequences (100000190 bp) in 1.670 CPU sec, 1.670 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 278880, 10, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 291, 852)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2214)
[M::mem_pestat] mean and std.dev: (472.35, 423.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2895)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 303, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 914)
[M::mem_pestat] mean and std.dev: (327.01, 160.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1153)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (124, 1429, 5746)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 16990)
[M::mem_pestat] mean and std.dev: (2944.70, 3559.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 22612)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 276, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 973)
[M::mem_pestat] mean and std.dev: (312.13, 208.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1240)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684338 reads in 236.609 CPU sec, 7.535 real sec
sorting block 97, #reads = 1061067 mem = 536880618 peak = 1072492544
[M::mem_process_seqs] Processed 684992 reads in 144.311 CPU sec, 4.588 real sec
sorting block 98, #reads = 1059432 mem = 536879125 peak = 1072492544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 278321, 14, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 302, 753)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1797)
[M::mem_pestat] mean and std.dev: (500.37, 445.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2319)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 308, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 932)
[M::mem_pestat] mean and std.dev: (332.11, 164.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1176)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (316, 751, 1597)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4159)
[M::mem_pestat] mean and std.dev: (945.14, 782.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5440)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (292, 385, 838)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1930)
[M::mem_pestat] mean and std.dev: (459.05, 301.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2476)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 692288 sequences (100000170 bp) in 3.169 CPU sec, 3.327 real sec...
[M::process] read 689158 sequences (100000017 bp) in 1.830 CPU sec, 1.830 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 280933, 9, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 242, 272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 534)
[M::mem_pestat] mean and std.dev: (208.11, 75.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 665)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 275, 406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 860)
[M::mem_pestat] mean and std.dev: (303.29, 155.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1087)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 280, 588)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1378)
[M::mem_pestat] mean and std.dev: (377.46, 227.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1773)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684256 reads in 212.876 CPU sec, 6.755 real sec
[M::process] read 688846 sequences (100000247 bp) in 2.392 CPU sec, 2.401 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 281629, 16, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 360, 880)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2228)
[M::mem_pestat] mean and std.dev: (510.50, 477.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2902)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 271, 399)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 845)
[M::mem_pestat] mean and std.dev: (297.56, 150.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1068)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (584, 1252, 3424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9104)
[M::mem_pestat] mean and std.dev: (2026.69, 1975.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11944)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 387, 854)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2190)
[M::mem_pestat] mean and std.dev: (478.88, 401.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2858)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 692288 reads in 122.713 CPU sec, 3.891 real sec
sorting block 99, #reads = 1059848 mem = 536878677 peak = 1072492544
[M::mem_process_seqs] Processed 691384 reads in 291.946 CPU sec, 9.287 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281747, 12, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 478, 1029)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2679)
[M::mem_pestat] mean and std.dev: (492.62, 371.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3504)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 285, 416)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 880)
[M::mem_pestat] mean and std.dev: (310.56, 155.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1112)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (313, 450, 1253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3133)
[M::mem_pestat] mean and std.dev: (477.40, 340.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4073)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 254, 397)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 829)
[M::mem_pestat] mean and std.dev: (269.31, 131.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1045)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 100, #reads = 1059157 mem = 536877402 peak = 1072492544
[M::process] read 688296 sequences (100000083 bp) in 3.217 CPU sec, 3.351 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 280720, 13, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 314, 599)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1391)
[M::mem_pestat] mean and std.dev: (388.11, 204.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1787)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 286, 418)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 884)
[M::mem_pestat] mean and std.dev: (311.99, 156.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1117)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (653, 2067, 2587)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6455)
[M::mem_pestat] mean and std.dev: (1709.92, 1071.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8389)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 284, 516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1114)
[M::mem_pestat] mean and std.dev: (367.55, 231.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1413)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 687110 sequences (100000279 bp) in 2.000 CPU sec, 2.005 real sec...
[M::mem_process_seqs] Processed 689158 reads in 230.962 CPU sec, 7.332 real sec
[M::mem_process_seqs] Processed 688846 reads in 137.450 CPU sec, 4.346 real sec
sorting block 101, #reads = 1061985 mem = 536880049 peak = 1072492544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281195, 11, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (307, 358, 518)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 940)
[M::mem_pestat] mean and std.dev: (368.53, 174.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1151)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 289, 421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 889)
[M::mem_pestat] mean and std.dev: (314.09, 156.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1123)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (287, 610, 1096)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2714)
[M::mem_pestat] mean and std.dev: (699.55, 579.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3523)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 246, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (217.87, 93.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 967)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 686592 sequences (100000011 bp) in 2.819 CPU sec, 2.971 real sec...
[M::process] read 685402 sequences (100000090 bp) in 2.020 CPU sec, 2.020 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 280893, 9, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 336, 712)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1764)
[M::mem_pestat] mean and std.dev: (450.73, 402.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2290)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 297, 428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 902)
[M::mem_pestat] mean and std.dev: (319.05, 156.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1139)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 355, 572)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1328)
[M::mem_pestat] mean and std.dev: (349.05, 265.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1706)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 688296 reads in 207.896 CPU sec, 6.601 real sec
[M::mem_process_seqs] Processed 687110 reads in 135.335 CPU sec, 4.302 real sec
sorting block 102, #reads = 1062976 mem = 536878948 peak = 1072492544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 280266, 8, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 248, 389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 803)
[M::mem_pestat] mean and std.dev: (267.00, 115.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1010)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 299, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 910)
[M::mem_pestat] mean and std.dev: (321.91, 158.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1149)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (278, 325, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 734)
[M::mem_pestat] mean and std.dev: (304.14, 92.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 886)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 686196 sequences (100000232 bp) in 3.074 CPU sec, 3.208 real sec...
[M::process] read 686820 sequences (100000153 bp) in 2.040 CPU sec, 2.032 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (14, 280607, 8, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (260, 393, 5614)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 16322)
[M::mem_pestat] mean and std.dev: (2072.86, 2919.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 21676)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 307, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 920)
[M::mem_pestat] mean and std.dev: (327.16, 159.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1161)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 322, 762)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1806)
[M::mem_pestat] mean and std.dev: (423.59, 293.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2328)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 686592 reads in 196.320 CPU sec, 6.226 real sec
sorting block 103, #reads = 1063170 mem = 536882944 peak = 1072492544
[M::mem_process_seqs] Processed 685402 reads in 129.665 CPU sec, 4.389 real sec
sorting block 104, #reads = 1063384 mem = 536882457 peak = 1072492544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 280382, 11, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 287, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1039)
[M::mem_pestat] mean and std.dev: (282.32, 141.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1334)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 300, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 910)
[M::mem_pestat] mean and std.dev: (323.01, 159.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1149)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (460, 942, 1064)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2272)
[M::mem_pestat] mean and std.dev: (835.00, 662.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3485)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 256, 599)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1467)
[M::mem_pestat] mean and std.dev: (269.83, 165.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1901)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 686464 sequences (100000013 bp) in 2.690 CPU sec, 2.830 real sec...
[M::process] read 686142 sequences (100000003 bp) in 1.700 CPU sec, 1.706 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 280549, 5, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 341, 982)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2592)
[M::mem_pestat] mean and std.dev: (382.54, 366.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3397)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 296, 429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 903)
[M::mem_pestat] mean and std.dev: (320.48, 159.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1140)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 259, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1054)
[M::mem_pestat] mean and std.dev: (290.38, 162.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1348)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 686196 reads in 201.303 CPU sec, 6.683 real sec
[M::mem_process_seqs] Processed 686820 reads in 131.011 CPU sec, 4.181 real sec
sorting block 105, #reads = 1066878 mem = 536879880 peak = 1072492544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 280614, 22, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 376, 820)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2184)
[M::mem_pestat] mean and std.dev: (435.81, 396.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2866)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 298, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 907)
[M::mem_pestat] mean and std.dev: (321.91, 159.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1145)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (323, 1956, 2412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6590)
[M::mem_pestat] mean and std.dev: (1275.44, 869.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8679)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (263, 345, 491)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 947)
[M::mem_pestat] mean and std.dev: (345.41, 140.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1175)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 686016 sequences (100000079 bp) in 2.731 CPU sec, 2.848 real sec...
[M::process] read 686464 sequences (100000020 bp) in 2.130 CPU sec, 2.131 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 280294, 10, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 205, 477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1109)
[M::mem_pestat] mean and std.dev: (238.93, 170.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1425)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 299, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 904)
[M::mem_pestat] mean and std.dev: (322.42, 159.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1141)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (526, 526, 526)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (526, 526)
[M::mem_pestat] mean and std.dev: (526.00, 0.00)
[M::mem_pestat] low and high boundaries for proper pairs: (526, 526)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (271, 392, 544)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1090)
[M::mem_pestat] mean and std.dev: (371.07, 171.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1363)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 686464 reads in 193.512 CPU sec, 6.138 real sec
[M::mem_process_seqs] Processed 686142 reads in 126.619 CPU sec, 4.009 real sec
sorting block 106, #reads = 1066992 mem = 536881443 peak = 1072492544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 279843, 3, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 284, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 973)
[M::mem_pestat] mean and std.dev: (302.54, 186.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1225)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 301, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 915)
[M::mem_pestat] mean and std.dev: (325.09, 161.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1155)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 331, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 893)
[M::mem_pestat] mean and std.dev: (316.54, 151.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1118)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 686740 sequences (100000174 bp) in 3.202 CPU sec, 3.330 real sec...
[M::process] read 685648 sequences (100000222 bp) in 1.630 CPU sec, 1.629 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 279801, 16, 15)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 273, 519)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1195)
[M::mem_pestat] mean and std.dev: (340.88, 225.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1533)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 298, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 904)
[M::mem_pestat] mean and std.dev: (321.76, 159.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1141)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (96, 803, 1695)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4893)
[M::mem_pestat] mean and std.dev: (604.57, 574.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6492)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (262, 327, 485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 931)
[M::mem_pestat] mean and std.dev: (349.07, 173.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1154)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 686016 reads in 193.062 CPU sec, 6.141 real sec
sorting block 107, #reads = 1066908 mem = 536876302 peak = 1072492544
[M::mem_process_seqs] Processed 686464 reads in 139.676 CPU sec, 4.465 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 279872, 12, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 321, 578)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1326)
[M::mem_pestat] mean and std.dev: (370.54, 269.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1700)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 296, 427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 899)
[M::mem_pestat] mean and std.dev: (319.55, 157.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1135)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (66, 379, 791)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2241)
[M::mem_pestat] mean and std.dev: (433.00, 443.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2966)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 420, 532)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1176)
[M::mem_pestat] mean and std.dev: (393.68, 267.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1498)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 689668 sequences (100000290 bp) in 2.808 CPU sec, 2.905 real sec...
[M::process] read 684404 sequences (100000078 bp) in 2.110 CPU sec, 2.109 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 279548, 12, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 284, 633)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1577)
[M::mem_pestat] mean and std.dev: (378.85, 337.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2049)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 301, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 915)
[M::mem_pestat] mean and std.dev: (324.84, 160.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1155)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 1296, 2659)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7525)
[M::mem_pestat] mean and std.dev: (1381.25, 1576.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9958)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 335, 579)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1223)
[M::mem_pestat] mean and std.dev: (358.67, 175.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1545)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 686740 reads in 204.685 CPU sec, 6.497 real sec
sorting block 108, #reads = 1064528 mem = 536877277 peak = 1072492544
[M::mem_process_seqs] Processed 685648 reads in 136.614 CPU sec, 4.330 real sec
sorting block 109, #reads = 1062647 mem = 536877737 peak = 1086410752
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 280139, 14, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 331, 709)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1739)
[M::mem_pestat] mean and std.dev: (424.06, 381.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2254)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 282, 410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 864)
[M::mem_pestat] mean and std.dev: (306.79, 153.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1091)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (53, 384, 883)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2543)
[M::mem_pestat] mean and std.dev: (692.21, 740.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3656)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 336, 562)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1212)
[M::mem_pestat] mean and std.dev: (349.34, 166.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1537)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683946 sequences (100000260 bp) in 3.247 CPU sec, 3.366 real sec...
[M::process] read 683926 sequences (100000160 bp) in 2.100 CPU sec, 2.104 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 278803, 20, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 294, 518)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1238)
[M::mem_pestat] mean and std.dev: (370.28, 272.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1598)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 311, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 944)
[M::mem_pestat] mean and std.dev: (334.21, 165.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1192)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (452, 452, 866)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1694)
[M::mem_pestat] mean and std.dev: (547.28, 275.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2108)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 289, 578)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1276)
[M::mem_pestat] mean and std.dev: (396.49, 245.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1625)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 689668 reads in 222.017 CPU sec, 7.049 real sec
[M::mem_process_seqs] Processed 684404 reads in 141.797 CPU sec, 4.510 real sec
sorting block 110, #reads = 1056558 mem = 536879056 peak = 1086410752
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 278783, 11, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 263, 1522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4210)
[M::mem_pestat] mean and std.dev: (562.19, 676.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5554)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 313, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 946)
[M::mem_pestat] mean and std.dev: (336.69, 167.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1194)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (376, 453, 1407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3469)
[M::mem_pestat] mean and std.dev: (702.80, 647.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4500)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (260, 459, 653)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1439)
[M::mem_pestat] mean and std.dev: (498.11, 338.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1850)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683340 sequences (100000131 bp) in 2.842 CPU sec, 2.961 real sec...
[M::process] read 683186 sequences (100000249 bp) in 2.110 CPU sec, 2.112 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 278697, 12, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (276, 418, 701)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1551)
[M::mem_pestat] mean and std.dev: (423.53, 242.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1976)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 312, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 948)
[M::mem_pestat] mean and std.dev: (336.46, 167.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1197)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (524, 778, 2124)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5324)
[M::mem_pestat] mean and std.dev: (955.50, 836.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6924)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 337, 787)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1951)
[M::mem_pestat] mean and std.dev: (523.49, 509.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2563)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683946 reads in 200.131 CPU sec, 6.353 real sec
sorting block 111, #reads = 1064805 mem = 536880101 peak = 1086410752
[M::mem_process_seqs] Processed 683926 reads in 132.471 CPU sec, 4.199 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 278191, 18, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 222, 410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 896)
[M::mem_pestat] mean and std.dev: (223.78, 108.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1139)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 315, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 956)
[M::mem_pestat] mean and std.dev: (339.60, 168.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1207)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (410, 672, 797)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1571)
[M::mem_pestat] mean and std.dev: (585.00, 360.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2026)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (258, 385, 581)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1227)
[M::mem_pestat] mean and std.dev: (346.77, 178.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1550)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683088 sequences (100000087 bp) in 2.887 CPU sec, 2.998 real sec...
[M::process] read 682662 sequences (100000062 bp) in 2.040 CPU sec, 2.042 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 278335, 16, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 256, 526)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1214)
[M::mem_pestat] mean and std.dev: (314.05, 218.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1558)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 317, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 966)
[M::mem_pestat] mean and std.dev: (341.90, 170.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1220)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (543, 1322, 2977)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7845)
[M::mem_pestat] mean and std.dev: (986.62, 753.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10279)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (275, 396, 528)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1034)
[M::mem_pestat] mean and std.dev: (337.91, 125.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1287)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683340 reads in 204.312 CPU sec, 6.772 real sec
sorting block 112, #reads = 1065143 mem = 536881473 peak = 1086410752
[M::mem_process_seqs] Processed 683186 reads in 132.282 CPU sec, 4.200 real sec
sorting block 113, #reads = 1065706 mem = 536877041 peak = 1086410752
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 278561, 5, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 324, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 996)
[M::mem_pestat] mean and std.dev: (295.17, 142.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1260)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 319, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 976)
[M::mem_pestat] mean and std.dev: (344.34, 172.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1233)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 388, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 805)
[M::mem_pestat] mean and std.dev: (328.92, 135.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 992)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682632 sequences (100000012 bp) in 2.618 CPU sec, 2.747 real sec...
[M::process] read 682646 sequences (100000206 bp) in 2.130 CPU sec, 2.129 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 278490, 13, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 457, 654)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1642)
[M::mem_pestat] mean and std.dev: (469.66, 321.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2136)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 323, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 984)
[M::mem_pestat] mean and std.dev: (347.48, 173.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1243)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (508, 508, 867)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1585)
[M::mem_pestat] mean and std.dev: (623.85, 254.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1944)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 308, 794)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1964)
[M::mem_pestat] mean and std.dev: (397.51, 349.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2549)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683088 reads in 197.789 CPU sec, 6.293 real sec
[M::mem_process_seqs] Processed 682662 reads in 141.961 CPU sec, 4.539 real sec
sorting block 114, #reads = 1065373 mem = 536879103 peak = 1086410752
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 278735, 9, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 387, 621)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1321)
[M::mem_pestat] mean and std.dev: (455.42, 270.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1671)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 321, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 975)
[M::mem_pestat] mean and std.dev: (346.38, 173.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1231)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 360, 659)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1521)
[M::mem_pestat] mean and std.dev: (399.48, 231.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1952)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 686892 sequences (100000185 bp) in 2.809 CPU sec, 2.908 real sec...
[M::process] read 687144 sequences (100000269 bp) in 1.660 CPU sec, 1.658 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 278055, 16, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 358, 570)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1346)
[M::mem_pestat] mean and std.dev: (446.44, 352.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1854)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 320, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 971)
[M::mem_pestat] mean and std.dev: (345.47, 173.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1226)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (287, 515, 3254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9188)
[M::mem_pestat] mean and std.dev: (1779.44, 2520.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12155)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (287, 447, 542)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1052)
[M::mem_pestat] mean and std.dev: (450.43, 204.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1307)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682632 reads in 197.886 CPU sec, 6.302 real sec
[M::mem_process_seqs] Processed 682646 reads in 134.647 CPU sec, 4.283 real sec
sorting block 115, #reads = 1064401 mem = 536882400 peak = 1086410752
[M::process] read 685832 sequences (100000154 bp) in 2.492 CPU sec, 2.589 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 279555, 9, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 450, 643)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1445)
[M::mem_pestat] mean and std.dev: (469.28, 321.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1846)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 297, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 923)
[M::mem_pestat] mean and std.dev: (325.05, 166.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1167)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (310, 422, 1291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3253)
[M::mem_pestat] mean and std.dev: (697.18, 646.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4234)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 685404 sequences (100000070 bp) in 2.098 CPU sec, 2.098 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 279687, 12, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 269, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 603)
[M::mem_pestat] mean and std.dev: (247.45, 84.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 746)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 305, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 954)
[M::mem_pestat] mean and std.dev: (333.00, 170.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1207)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (124, 698, 8603)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 25561)
[M::mem_pestat] mean and std.dev: (2880.92, 3631.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 34040)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 262, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 743)
[M::mem_pestat] mean and std.dev: (272.17, 126.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 932)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 280307, 14, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 281, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 910)
[M::mem_pestat] mean and std.dev: (265.28, 108.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1146)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 298, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 938)
[M::mem_pestat] mean and std.dev: (327.49, 168.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1187)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (878, 3470, 3527)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8825)
[M::mem_pestat] mean and std.dev: (2620.50, 2117.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11474)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (304, 525, 1388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3556)
[M::mem_pestat] mean and std.dev: (849.66, 715.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4640)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 686892 reads in 288.867 CPU sec, 9.229 real sec
sorting block 116, #reads = 1058863 mem = 536887810 peak = 1086410752
[M::mem_process_seqs] Processed 685832 reads in 207.303 CPU sec, 6.638 real sec
[M::mem_process_seqs] Processed 687144 reads in 228.744 CPU sec, 7.354 real sec
sorting block 117, #reads = 1065449 mem = 536881750 peak = 1086410752
[M::process] read 685224 sequences (100000235 bp) in 2.781 CPU sec, 2.966 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 280171, 5, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 231, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (285.66, 145.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 951)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 309, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 956)
[M::mem_pestat] mean and std.dev: (334.79, 170.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1209)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 261, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 914)
[M::mem_pestat] mean and std.dev: (296.97, 157.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1155)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 684736 sequences (100000067 bp) in 2.496 CPU sec, 2.652 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 279576, 7, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 400, 2122)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5964)
[M::mem_pestat] mean and std.dev: (1440.38, 2033.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9574)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 308, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 953)
[M::mem_pestat] mean and std.dev: (334.11, 168.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1205)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 304, 781)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1953)
[M::mem_pestat] mean and std.dev: (331.20, 224.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2539)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 685404 reads in 187.935 CPU sec, 6.065 real sec
[M::mem_process_seqs] Processed 685224 reads in 126.256 CPU sec, 4.016 real sec
sorting block 118, #reads = 1069780 mem = 536879761 peak = 1086410752
[M::process] read 683728 sequences (100000054 bp) in 2.231 CPU sec, 2.382 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 279936, 9, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (270, 365, 523)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1029)
[M::mem_pestat] mean and std.dev: (332.16, 163.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1282)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 312, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 950)
[M::mem_pestat] mean and std.dev: (336.39, 168.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1200)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 294, 637)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1475)
[M::mem_pestat] mean and std.dev: (390.69, 254.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1894)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683428 sequences (100000278 bp) in 2.569 CPU sec, 2.711 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (18, 279203, 7, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 287, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 908)
[M::mem_pestat] mean and std.dev: (268.00, 106.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1140)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 320, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 958)
[M::mem_pestat] mean and std.dev: (341.78, 169.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1209)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 288, 396)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 742)
[M::mem_pestat] mean and std.dev: (303.66, 135.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 915)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683292 sequences (100000055 bp) in 1.620 CPU sec, 1.626 real sec...
[M::mem_process_seqs] Processed 684736 reads in 185.621 CPU sec, 5.907 real sec
sorting block 119, #reads = 1069593 mem = 536878523 peak = 1086410752
[M::mem_process_seqs] Processed 683728 reads in 121.514 CPU sec, 4.096 real sec
sorting block 120, #reads = 1069268 mem = 536880484 peak = 1086410752
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 279524, 9, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 789, 812)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1942)
[M::mem_pestat] mean and std.dev: (549.57, 392.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2507)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 322, 460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 970)
[M::mem_pestat] mean and std.dev: (343.30, 169.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1225)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (301, 457, 1186)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2956)
[M::mem_pestat] mean and std.dev: (578.27, 427.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3841)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683170 sequences (100000262 bp) in 2.782 CPU sec, 2.975 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 278982, 3, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 326, 1377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3715)
[M::mem_pestat] mean and std.dev: (660.50, 665.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4884)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 322, 460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 970)
[M::mem_pestat] mean and std.dev: (343.95, 170.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1225)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (317, 556, 1041)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2489)
[M::mem_pestat] mean and std.dev: (664.88, 541.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3213)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683946 sequences (100000141 bp) in 1.980 CPU sec, 1.977 real sec...
[M::mem_process_seqs] Processed 683428 reads in 189.021 CPU sec, 6.253 real sec
[M::mem_process_seqs] Processed 683292 reads in 123.243 CPU sec, 4.002 real sec
sorting block 121, #reads = 1069698 mem = 536877382 peak = 1086410752
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 278974, 13, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 399, 495)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1059)
[M::mem_pestat] mean and std.dev: (354.52, 168.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1341)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 325, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 983)
[M::mem_pestat] mean and std.dev: (346.74, 172.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1242)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (415, 702, 1121)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2533)
[M::mem_pestat] mean and std.dev: (782.58, 455.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3239)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 438, 681)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1659)
[M::mem_pestat] mean and std.dev: (492.29, 367.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2148)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 685740 sequences (100000241 bp) in 2.506 CPU sec, 2.652 real sec...
[M::process] read 685372 sequences (100000060 bp) in 1.800 CPU sec, 1.797 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 279684, 13, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 251, 377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 819)
[M::mem_pestat] mean and std.dev: (244.25, 106.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1040)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 318, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 964)
[M::mem_pestat] mean and std.dev: (340.67, 169.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1218)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1082, 1082, 2424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5108)
[M::mem_pestat] mean and std.dev: (1313.15, 747.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6450)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (329, 508, 950)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2192)
[M::mem_pestat] mean and std.dev: (711.50, 499.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2813)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683170 reads in 185.922 CPU sec, 6.006 real sec
[M::mem_process_seqs] Processed 683946 reads in 120.242 CPU sec, 3.911 real sec
sorting block 122, #reads = 1069220 mem = 536878984 peak = 1086410752
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 279973, 13, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 257, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 946)
[M::mem_pestat] mean and std.dev: (286.77, 144.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1190)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 303, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 938)
[M::mem_pestat] mean and std.dev: (329.10, 166.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1186)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (541, 541, 4213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11557)
[M::mem_pestat] mean and std.dev: (1615.31, 2022.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 15229)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 249, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 644)
[M::mem_pestat] mean and std.dev: (253.28, 85.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 791)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 684228 sequences (100000056 bp) in 2.622 CPU sec, 2.805 real sec...
[M::process] read 684270 sequences (100000182 bp) in 1.720 CPU sec, 1.714 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 279896, 5, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 377, 580)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1420)
[M::mem_pestat] mean and std.dev: (343.64, 230.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1840)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 305, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 937)
[M::mem_pestat] mean and std.dev: (330.81, 166.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1184)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 313, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 583)
[M::mem_pestat] mean and std.dev: (270.88, 102.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 703)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 685740 reads in 186.853 CPU sec, 6.038 real sec
sorting block 123, #reads = 1070468 mem = 536882738 peak = 1086410752
[M::mem_process_seqs] Processed 685372 reads in 124.026 CPU sec, 3.952 real sec
sorting block 124, #reads = 1069674 mem = 536877108 peak = 1086410752
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 279975, 5, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 332, 381)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 725)
[M::mem_pestat] mean and std.dev: (304.58, 127.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 897)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 313, 451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 951)
[M::mem_pestat] mean and std.dev: (337.06, 168.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1201)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 289, 425)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 883)
[M::mem_pestat] mean and std.dev: (342.97, 224.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1243)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 684314 sequences (100000101 bp) in 2.638 CPU sec, 2.802 real sec...
[M::process] read 683488 sequences (100000016 bp) in 1.790 CPU sec, 1.790 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 279764, 12, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 241, 400)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 894)
[M::mem_pestat] mean and std.dev: (259.89, 134.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1141)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 314, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 954)
[M::mem_pestat] mean and std.dev: (337.95, 169.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1205)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (706, 2866, 4141)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11011)
[M::mem_pestat] mean and std.dev: (1997.08, 1604.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14446)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 300, 2050)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5738)
[M::mem_pestat] mean and std.dev: (1023.08, 1425.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7582)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684228 reads in 181.826 CPU sec, 5.796 real sec
[M::process] read 683204 sequences (100000301 bp) in 2.196 CPU sec, 2.206 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 279854, 11, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 288, 783)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1961)
[M::mem_pestat] mean and std.dev: (432.45, 361.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2550)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 313, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 954)
[M::mem_pestat] mean and std.dev: (337.43, 168.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1205)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (288, 573, 1625)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4299)
[M::mem_pestat] mean and std.dev: (1011.82, 1244.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5990)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 334, 631)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1601)
[M::mem_pestat] mean and std.dev: (412.17, 365.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2086)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684314 reads in 108.834 CPU sec, 3.772 real sec
sorting block 125, #reads = 1069450 mem = 536879638 peak = 1086410752
[M::mem_process_seqs] Processed 684270 reads in 265.566 CPU sec, 8.777 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 279022, 12, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 299, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 940)
[M::mem_pestat] mean and std.dev: (300.00, 145.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1184)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 318, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 966)
[M::mem_pestat] mean and std.dev: (342.47, 171.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1220)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1099, 1252, 1957)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3673)
[M::mem_pestat] mean and std.dev: (1413.25, 896.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4999)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 313, 491)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1113)
[M::mem_pestat] mean and std.dev: (300.17, 150.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1424)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 126, #reads = 1068186 mem = 536878796 peak = 1086410752
[M::process] read 682760 sequences (100000129 bp) in 2.760 CPU sec, 3.116 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 279009, 14, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 347, 532)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1212)
[M::mem_pestat] mean and std.dev: (359.64, 254.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1552)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 320, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 973)
[M::mem_pestat] mean and std.dev: (344.54, 172.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1229)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (12, 665, 2090)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6246)
[M::mem_pestat] mean and std.dev: (935.93, 1163.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8324)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 374, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 954)
[M::mem_pestat] mean and std.dev: (350.00, 173.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1197)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683416 sequences (100000054 bp) in 1.690 CPU sec, 1.692 real sec...
[M::mem_process_seqs] Processed 683488 reads in 225.392 CPU sec, 7.204 real sec
[M::mem_process_seqs] Processed 683204 reads in 130.322 CPU sec, 4.132 real sec
sorting block 127, #reads = 1067367 mem = 536879550 peak = 1086410752
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 277712, 17, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 197, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 782)
[M::mem_pestat] mean and std.dev: (261.45, 151.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 990)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 321, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 974)
[M::mem_pestat] mean and std.dev: (345.90, 173.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1230)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (541, 911, 4597)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12709)
[M::mem_pestat] mean and std.dev: (1806.12, 1801.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16765)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (322, 510, 760)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1636)
[M::mem_pestat] mean and std.dev: (477.04, 231.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2074)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 684830 sequences (100000108 bp) in 2.899 CPU sec, 3.072 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 278589, 19, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 258, 487)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1067)
[M::mem_pestat] mean and std.dev: (352.64, 229.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1357)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 316, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 957)
[M::mem_pestat] mean and std.dev: (341.30, 170.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1208)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (323, 410, 4658)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13328)
[M::mem_pestat] mean and std.dev: (1801.32, 2460.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17663)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (261, 413, 676)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1506)
[M::mem_pestat] mean and std.dev: (471.40, 310.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1921)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683714 sequences (100000183 bp) in 2.070 CPU sec, 2.079 real sec...
[M::mem_process_seqs] Processed 682760 reads in 195.180 CPU sec, 6.272 real sec
[M::mem_process_seqs] Processed 683416 reads in 125.525 CPU sec, 4.082 real sec
sorting block 128, #reads = 1067925 mem = 536876600 peak = 1086410752
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 279269, 8, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 262, 490)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1156)
[M::mem_pestat] mean and std.dev: (306.07, 221.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1489)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 306, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 933)
[M::mem_pestat] mean and std.dev: (332.19, 166.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1178)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 323, 572)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1234)
[M::mem_pestat] mean and std.dev: (353.42, 199.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1565)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683538 sequences (100000079 bp) in 2.675 CPU sec, 2.814 real sec...
[M::process] read 683298 sequences (100000137 bp) in 2.140 CPU sec, 2.136 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 279359, 12, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 295, 397)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 781)
[M::mem_pestat] mean and std.dev: (315.58, 146.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 973)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 313, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 960)
[M::mem_pestat] mean and std.dev: (339.01, 170.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1213)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (71, 612, 3069)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9065)
[M::mem_pestat] mean and std.dev: (1487.50, 2126.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12063)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 293, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 929)
[M::mem_pestat] mean and std.dev: (314.02, 137.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1164)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684830 reads in 205.900 CPU sec, 6.634 real sec
[M::mem_process_seqs] Processed 683714 reads in 129.663 CPU sec, 4.112 real sec
sorting block 129, #reads = 1064913 mem = 536883803 peak = 1086410752
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 278491, 14, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 323, 512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1188)
[M::mem_pestat] mean and std.dev: (317.32, 174.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1526)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 313, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 961)
[M::mem_pestat] mean and std.dev: (339.98, 171.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1214)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (516, 623, 623)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (302, 837)
[M::mem_pestat] mean and std.dev: (585.73, 76.96)
[M::mem_pestat] low and high boundaries for proper pairs: (195, 944)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (297, 415, 644)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1338)
[M::mem_pestat] mean and std.dev: (455.42, 262.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1685)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683768 sequences (100000071 bp) in 2.914 CPU sec, 3.070 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 278249, 17, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 307, 766)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1954)
[M::mem_pestat] mean and std.dev: (468.13, 419.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2548)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 315, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 962)
[M::mem_pestat] mean and std.dev: (341.33, 171.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1215)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (254, 541, 1433)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3791)
[M::mem_pestat] mean and std.dev: (610.00, 539.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4970)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 282, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1012)
[M::mem_pestat] mean and std.dev: (331.93, 188.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1285)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683684 sequences (100000272 bp) in 2.130 CPU sec, 2.128 real sec...
[M::mem_process_seqs] Processed 683538 reads in 195.102 CPU sec, 6.207 real sec
sorting block 130, #reads = 1064795 mem = 536881884 peak = 1086410752
[M::mem_process_seqs] Processed 683298 reads in 127.537 CPU sec, 4.091 real sec
sorting block 131, #reads = 1065598 mem = 536878010 peak = 1086410752
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 278512, 14, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 355, 501)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1023)
[M::mem_pestat] mean and std.dev: (307.02, 133.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1284)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 313, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 961)
[M::mem_pestat] mean and std.dev: (340.38, 172.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1214)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (506, 1352, 2045)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5123)
[M::mem_pestat] mean and std.dev: (1208.85, 778.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6662)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 283, 403)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 785)
[M::mem_pestat] mean and std.dev: (310.85, 144.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 976)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683682 sequences (100000004 bp) in 2.652 CPU sec, 2.794 real sec...
[M::process] read 684098 sequences (100000112 bp) in 1.590 CPU sec, 1.597 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 278536, 14, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 273, 526)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1232)
[M::mem_pestat] mean and std.dev: (302.36, 232.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1585)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 311, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 960)
[M::mem_pestat] mean and std.dev: (339.16, 172.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1213)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (40, 564, 2401)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7123)
[M::mem_pestat] mean and std.dev: (1497.00, 1934.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9484)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 332, 401)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (300.88, 126.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 959)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683768 reads in 189.507 CPU sec, 6.077 real sec
[M::mem_process_seqs] Processed 683684 reads in 117.466 CPU sec, 3.738 real sec
sorting block 132, #reads = 1064995 mem = 536878022 peak = 1086410752
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 278846, 7, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 357, 944)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2516)
[M::mem_pestat] mean and std.dev: (582.68, 625.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3302)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 313, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 967)
[M::mem_pestat] mean and std.dev: (341.94, 174.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1222)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 297, 509)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1113)
[M::mem_pestat] mean and std.dev: (322.41, 180.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1415)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683486 sequences (100000247 bp) in 2.439 CPU sec, 2.579 real sec...
[M::process] read 685952 sequences (100000280 bp) in 1.780 CPU sec, 1.783 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 278921, 6, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 365, 930)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2316)
[M::mem_pestat] mean and std.dev: (519.12, 393.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3009)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 308, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 947)
[M::mem_pestat] mean and std.dev: (336.55, 170.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1196)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 331, 460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 988)
[M::mem_pestat] mean and std.dev: (328.78, 143.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1252)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683682 reads in 178.301 CPU sec, 5.674 real sec
[M::mem_process_seqs] Processed 684098 reads in 122.886 CPU sec, 3.902 real sec
sorting block 133, #reads = 1065570 mem = 536878964 peak = 1086410752
[M::process] read 690498 sequences (100000210 bp) in 2.739 CPU sec, 2.856 real sec...
[M::process] read 688188 sequences (100000145 bp) in 1.630 CPU sec, 1.625 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 279454, 10, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 315, 630)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1466)
[M::mem_pestat] mean and std.dev: (369.17, 208.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1884)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 299, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 926)
[M::mem_pestat] mean and std.dev: (327.57, 167.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1170)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (18, 926, 1423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4233)
[M::mem_pestat] mean and std.dev: (566.88, 574.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5638)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 278, 713)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1745)
[M::mem_pestat] mean and std.dev: (452.08, 407.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2261)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 685952 reads in 114.014 CPU sec, 3.766 real sec
sorting block 134, #reads = 1063239 mem = 536883984 peak = 1086410752
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 278526, 9, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 351, 681)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1653)
[M::mem_pestat] mean and std.dev: (388.71, 249.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2139)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 311, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 946)
[M::mem_pestat] mean and std.dev: (338.18, 170.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1194)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 263, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 618)
[M::mem_pestat] mean and std.dev: (245.85, 95.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 762)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 686656 sequences (100000211 bp) in 1.720 CPU sec, 1.725 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 281432, 9, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 313, 857)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2261)
[M::mem_pestat] mean and std.dev: (435.70, 341.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2963)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 278, 415)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 885)
[M::mem_pestat] mean and std.dev: (309.58, 161.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1120)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (327, 475, 1292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3222)
[M::mem_pestat] mean and std.dev: (471.30, 257.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4187)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683486 reads in 315.691 CPU sec, 10.200 real sec
[M::mem_process_seqs] Processed 690498 reads in 157.927 CPU sec, 5.285 real sec
sorting block 135, #reads = 1058715 mem = 536880104 peak = 1086410752
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 280699, 10, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 289, 397)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 879)
[M::mem_pestat] mean and std.dev: (319.30, 192.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1120)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 290, 429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 913)
[M::mem_pestat] mean and std.dev: (319.01, 163.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1155)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (460, 1105, 1105)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2395)
[M::mem_pestat] mean and std.dev: (838.00, 347.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3040)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 305, 428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 934)
[M::mem_pestat] mean and std.dev: (295.67, 136.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1187)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 686026 sequences (100000200 bp) in 3.031 CPU sec, 3.221 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 280193, 12, 19)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 296, 1656)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4690)
[M::mem_pestat] mean and std.dev: (522.55, 621.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6207)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 300, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 933)
[M::mem_pestat] mean and std.dev: (326.54, 165.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1180)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (458, 1336, 2211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5717)
[M::mem_pestat] mean and std.dev: (1183.64, 936.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7470)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (277, 518, 742)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1672)
[M::mem_pestat] mean and std.dev: (430.62, 218.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2137)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 685602 sequences (100000226 bp) in 2.030 CPU sec, 2.032 real sec...
[M::mem_process_seqs] Processed 688188 reads in 192.734 CPU sec, 6.194 real sec
sorting block 136, #reads = 1062924 mem = 536878596 peak = 1086410752
[M::mem_process_seqs] Processed 686656 reads in 121.421 CPU sec, 3.840 real sec
sorting block 137, #reads = 1065178 mem = 536881602 peak = 1086410752
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 280187, 9, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 291, 578)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1434)
[M::mem_pestat] mean and std.dev: (355.74, 232.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1862)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 304, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 939)
[M::mem_pestat] mean and std.dev: (329.72, 166.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1187)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (259, 376, 529)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1069)
[M::mem_pestat] mean and std.dev: (342.46, 144.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1339)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 684760 sequences (100000138 bp) in 2.915 CPU sec, 3.094 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 280038, 4, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 212, 404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 894)
[M::mem_pestat] mean and std.dev: (254.27, 145.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1139)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 307, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 937)
[M::mem_pestat] mean and std.dev: (331.21, 166.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1184)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 388, 522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1134)
[M::mem_pestat] mean and std.dev: (354.57, 198.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1440)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 684418 sequences (100000045 bp) in 2.130 CPU sec, 2.132 real sec...
[M::mem_process_seqs] Processed 686026 reads in 187.641 CPU sec, 5.942 real sec
[M::mem_process_seqs] Processed 685602 reads in 126.627 CPU sec, 4.006 real sec
sorting block 138, #reads = 1065802 mem = 536876280 peak = 1086410752
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 280090, 11, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (280, 480, 2367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6541)
[M::mem_pestat] mean and std.dev: (1510.45, 1912.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9161)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 311, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 949)
[M::mem_pestat] mean and std.dev: (334.85, 166.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1199)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (528, 874, 8899)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 25641)
[M::mem_pestat] mean and std.dev: (3295.82, 3784.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 34012)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (384, 481, 874)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1854)
[M::mem_pestat] mean and std.dev: (571.20, 367.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2344)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683806 sequences (100000065 bp) in 2.592 CPU sec, 2.748 real sec...
[M::process] read 683886 sequences (100000171 bp) in 2.000 CPU sec, 2.002 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 279459, 6, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 391, 514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1096)
[M::mem_pestat] mean and std.dev: (317.40, 128.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1387)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 315, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 956)
[M::mem_pestat] mean and std.dev: (336.68, 166.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1208)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (399, 609, 768)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1506)
[M::mem_pestat] mean and std.dev: (518.25, 187.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1875)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684760 reads in 193.211 CPU sec, 6.405 real sec
[M::mem_process_seqs] Processed 684418 reads in 126.254 CPU sec, 4.030 real sec
sorting block 139, #reads = 1065655 mem = 536879378 peak = 1086410752
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 279212, 13, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 335, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 814)
[M::mem_pestat] mean and std.dev: (341.11, 155.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1000)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 321, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 969)
[M::mem_pestat] mean and std.dev: (341.79, 168.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1224)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (320, 446, 575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1085)
[M::mem_pestat] mean and std.dev: (435.17, 163.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1340)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 350, 424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 794)
[M::mem_pestat] mean and std.dev: (322.20, 138.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 979)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 684742 sequences (100000246 bp) in 2.705 CPU sec, 2.876 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 278836, 20, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (115, 243, 473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1189)
[M::mem_pestat] mean and std.dev: (254.87, 166.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1547)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 319, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 965)
[M::mem_pestat] mean and std.dev: (340.82, 168.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1219)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 397, 2207)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6109)
[M::mem_pestat] mean and std.dev: (749.05, 886.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8060)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 392, 682)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1532)
[M::mem_pestat] mean and std.dev: (424.81, 233.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1957)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 684034 sequences (100000223 bp) in 2.030 CPU sec, 2.021 real sec...
[M::mem_process_seqs] Processed 683806 reads in 183.226 CPU sec, 5.815 real sec
sorting block 140, #reads = 1064690 mem = 536879017 peak = 1086410752
[M::mem_process_seqs] Processed 683886 reads in 121.382 CPU sec, 3.836 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 279311, 9, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 178, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1006)
[M::mem_pestat] mean and std.dev: (239.64, 162.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1294)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 310, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 943)
[M::mem_pestat] mean and std.dev: (333.99, 165.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1191)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (268, 386, 609)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1291)
[M::mem_pestat] mean and std.dev: (392.03, 190.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1632)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683502 sequences (100000231 bp) in 2.325 CPU sec, 2.497 real sec...
[M::process] read 683260 sequences (100000240 bp) in 1.600 CPU sec, 1.593 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 278549, 16, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 255, 402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 840)
[M::mem_pestat] mean and std.dev: (278.23, 117.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1059)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 313, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 940)
[M::mem_pestat] mean and std.dev: (335.48, 165.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1186)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (458, 1121, 1938)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4898)
[M::mem_pestat] mean and std.dev: (1002.00, 788.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6378)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 284, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 964)
[M::mem_pestat] mean and std.dev: (333.75, 186.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1215)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684742 reads in 180.557 CPU sec, 5.751 real sec
sorting block 141, #reads = 1065859 mem = 536878240 peak = 1086410752
[M::mem_process_seqs] Processed 684034 reads in 121.190 CPU sec, 3.858 real sec
sorting block 142, #reads = 1066989 mem = 536877979 peak = 1086410752
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 278572, 11, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 290, 524)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1176)
[M::mem_pestat] mean and std.dev: (336.65, 185.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1502)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 316, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 950)
[M::mem_pestat] mean and std.dev: (338.22, 165.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1199)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1487, 1609, 6204)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 15638)
[M::mem_pestat] mean and std.dev: (2731.09, 2768.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 20355)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 234, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 752)
[M::mem_pestat] mean and std.dev: (291.55, 169.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 968)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683054 sequences (100000141 bp) in 2.601 CPU sec, 2.731 real sec...
[M::process] read 683676 sequences (100000001 bp) in 1.590 CPU sec, 1.594 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 278766, 10, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (319, 524, 1160)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2842)
[M::mem_pestat] mean and std.dev: (681.86, 511.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3683)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 318, 451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 943)
[M::mem_pestat] mean and std.dev: (338.72, 165.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1189)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (323, 1501, 2516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6902)
[M::mem_pestat] mean and std.dev: (1508.10, 1362.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9095)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 401, 1367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3687)
[M::mem_pestat] mean and std.dev: (608.17, 616.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4847)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683502 reads in 183.948 CPU sec, 5.857 real sec
[M::mem_process_seqs] Processed 683260 reads in 122.768 CPU sec, 3.978 real sec
sorting block 143, #reads = 1065334 mem = 536879322 peak = 1086410752
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 278561, 6, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 297, 433)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 855)
[M::mem_pestat] mean and std.dev: (306.88, 159.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1066)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 318, 451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 943)
[M::mem_pestat] mean and std.dev: (338.72, 164.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1189)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 364, 562)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1286)
[M::mem_pestat] mean and std.dev: (354.80, 164.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1648)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682924 sequences (100000280 bp) in 2.819 CPU sec, 2.945 real sec...
[M::process] read 682566 sequences (100000207 bp) in 2.060 CPU sec, 2.062 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 278526, 9, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 349, 634)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1550)
[M::mem_pestat] mean and std.dev: (440.10, 340.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2008)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 312, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 917)
[M::mem_pestat] mean and std.dev: (331.89, 160.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1155)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 324, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 931)
[M::mem_pestat] mean and std.dev: (327.66, 151.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1168)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683054 reads in 194.979 CPU sec, 6.249 real sec
[M::mem_process_seqs] Processed 683676 reads in 125.732 CPU sec, 3.978 real sec
sorting block 144, #reads = 1066412 mem = 536886098 peak = 1086410752
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 278472, 15, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 321, 644)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1526)
[M::mem_pestat] mean and std.dev: (410.68, 330.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1967)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 316, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 922)
[M::mem_pestat] mean and std.dev: (335.33, 161.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1161)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (349, 944, 977)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2233)
[M::mem_pestat] mean and std.dev: (601.08, 308.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2861)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 234, 535)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1199)
[M::mem_pestat] mean and std.dev: (313.27, 223.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1531)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682654 sequences (100000150 bp) in 2.291 CPU sec, 2.418 real sec...
[M::process] read 682572 sequences (100000104 bp) in 1.480 CPU sec, 1.484 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 278163, 13, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 407, 974)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2534)
[M::mem_pestat] mean and std.dev: (488.60, 450.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3314)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 315, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 923)
[M::mem_pestat] mean and std.dev: (335.91, 162.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1162)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 431, 2686)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7608)
[M::mem_pestat] mean and std.dev: (1189.08, 1360.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10069)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 328, 485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1063)
[M::mem_pestat] mean and std.dev: (342.87, 163.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1352)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682924 reads in 164.207 CPU sec, 5.302 real sec
sorting block 145, #reads = 1062239 mem = 536879055 peak = 1086410752
[M::mem_process_seqs] Processed 682566 reads in 106.975 CPU sec, 3.405 real sec
sorting block 146, #reads = 1064812 mem = 536880536 peak = 1086410752
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 277758, 5, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 309, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (303.45, 146.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 890)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 315, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 923)
[M::mem_pestat] mean and std.dev: (335.96, 162.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1162)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 300, 484)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1066)
[M::mem_pestat] mean and std.dev: (321.69, 222.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1357)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682524 sequences (100000289 bp) in 2.159 CPU sec, 2.271 real sec...
[M::process] read 682352 sequences (100000013 bp) in 1.470 CPU sec, 1.476 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 277993, 14, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 270, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 932)
[M::mem_pestat] mean and std.dev: (351.12, 232.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1281)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 315, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 923)
[M::mem_pestat] mean and std.dev: (336.54, 162.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1162)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (317, 751, 751)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1619)
[M::mem_pestat] mean and std.dev: (588.15, 354.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2053)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 278, 616)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1554)
[M::mem_pestat] mean and std.dev: (339.65, 269.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2023)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682654 reads in 161.729 CPU sec, 5.166 real sec
[M::mem_process_seqs] Processed 682572 reads in 104.765 CPU sec, 3.334 real sec
sorting block 147, #reads = 1065727 mem = 536882248 peak = 1086410752
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 277824, 13, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 298, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1046)
[M::mem_pestat] mean and std.dev: (284.09, 168.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1340)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 315, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 920)
[M::mem_pestat] mean and std.dev: (335.69, 161.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1158)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (691, 936, 1640)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3538)
[M::mem_pestat] mean and std.dev: (870.67, 518.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4487)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (266, 403, 871)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2081)
[M::mem_pestat] mean and std.dev: (542.46, 436.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2686)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682672 sequences (100000240 bp) in 2.661 CPU sec, 2.789 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 278065, 17, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 319, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 932)
[M::mem_pestat] mean and std.dev: (279.50, 117.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1182)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 315, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 918)
[M::mem_pestat] mean and std.dev: (335.94, 162.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1155)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 426, 1298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3464)
[M::mem_pestat] mean and std.dev: (631.62, 814.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4547)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 301, 554)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1240)
[M::mem_pestat] mean and std.dev: (358.16, 234.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1583)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682494 sequences (100000247 bp) in 1.882 CPU sec, 1.884 real sec...
[M::mem_process_seqs] Processed 682524 reads in 165.830 CPU sec, 5.269 real sec
[M::mem_process_seqs] Processed 682352 reads in 106.900 CPU sec, 3.392 real sec
sorting block 148, #reads = 1066785 mem = 536882198 peak = 1086410752
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 278052, 11, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 233, 863)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2201)
[M::mem_pestat] mean and std.dev: (489.29, 456.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2870)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 312, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 913)
[M::mem_pestat] mean and std.dev: (334.37, 162.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1149)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (742, 1345, 2516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6064)
[M::mem_pestat] mean and std.dev: (1413.55, 998.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7838)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 340, 516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1126)
[M::mem_pestat] mean and std.dev: (320.81, 200.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1431)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682302 sequences (100000237 bp) in 2.638 CPU sec, 2.740 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 278249, 6, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 280, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 648)
[M::mem_pestat] mean and std.dev: (265.70, 135.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 808)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 314, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 917)
[M::mem_pestat] mean and std.dev: (335.95, 163.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1154)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 370, 552)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1330)
[M::mem_pestat] mean and std.dev: (340.29, 238.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1719)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682224 sequences (100000108 bp) in 1.660 CPU sec, 1.661 real sec...
[M::mem_process_seqs] Processed 682672 reads in 161.082 CPU sec, 5.111 real sec
sorting block 149, #reads = 1066983 mem = 536880165 peak = 1086410752
[M::mem_process_seqs] Processed 682494 reads in 105.980 CPU sec, 3.345 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 277307, 13, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 407, 1358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3690)
[M::mem_pestat] mean and std.dev: (780.27, 839.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4856)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 316, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 921)
[M::mem_pestat] mean and std.dev: (337.24, 163.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1159)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (328, 565, 2522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6910)
[M::mem_pestat] mean and std.dev: (1135.77, 1212.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9104)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 288, 693)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1713)
[M::mem_pestat] mean and std.dev: (389.63, 365.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2223)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 150, #reads = 1066903 mem = 536880483 peak = 1086410752
[M::process] read 682124 sequences (100000096 bp) in 2.646 CPU sec, 2.760 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 277998, 6, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 401, 1189)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3257)
[M::mem_pestat] mean and std.dev: (623.33, 645.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4291)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 317, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 925)
[M::mem_pestat] mean and std.dev: (338.42, 164.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1164)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 426, 1437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3875)
[M::mem_pestat] mean and std.dev: (663.78, 531.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5094)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682170 sequences (100000046 bp) in 1.880 CPU sec, 1.879 real sec...
[M::mem_process_seqs] Processed 682302 reads in 161.794 CPU sec, 5.199 real sec
[M::mem_process_seqs] Processed 682224 reads in 101.659 CPU sec, 3.206 real sec
sorting block 151, #reads = 1066377 mem = 536879373 peak = 1086410752
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 277455, 7, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 382, 717)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1667)
[M::mem_pestat] mean and std.dev: (419.20, 322.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2142)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 318, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 926)
[M::mem_pestat] mean and std.dev: (339.42, 164.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1165)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 298, 653)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1569)
[M::mem_pestat] mean and std.dev: (398.75, 327.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2027)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681868 sequences (100000144 bp) in 2.555 CPU sec, 2.699 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 278184, 14, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 247, 707)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1765)
[M::mem_pestat] mean and std.dev: (369.86, 307.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2294)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 318, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 934)
[M::mem_pestat] mean and std.dev: (340.45, 166.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1176)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (669, 1823, 5759)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 15939)
[M::mem_pestat] mean and std.dev: (3215.79, 3075.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 21029)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 308, 391)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 777)
[M::mem_pestat] mean and std.dev: (316.32, 143.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 970)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682124 reads in 154.420 CPU sec, 4.911 real sec
[M::mem_process_seqs] Processed 682170 reads in 101.155 CPU sec, 3.182 real sec
[M::process] read 672270 sequences (98464862 bp) in 2.051 CPU sec, 2.072 real sec...
sorting block 152, #reads = 1067277 mem = 536881228 peak = 1086410752
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 278431, 20, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 339, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 989)
[M::mem_pestat] mean and std.dev: (315.44, 150.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1259)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 320, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 941)
[M::mem_pestat] mean and std.dev: (342.70, 167.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1185)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 736, 3385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9883)
[M::mem_pestat] mean and std.dev: (1789.60, 2415.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13132)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 346, 589)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1267)
[M::mem_pestat] mean and std.dev: (391.65, 268.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1606)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 273903, 15, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 276, 424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 956)
[M::mem_pestat] mean and std.dev: (249.10, 138.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1222)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 315, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 934)
[M::mem_pestat] mean and std.dev: (338.05, 166.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1177)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1615, 1615, 1788)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1269, 2134)
[M::mem_pestat] mean and std.dev: (1711.33, 119.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1096, 2307)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 514, 1123)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2883)
[M::mem_pestat] mean and std.dev: (640.20, 484.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3763)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681868 reads in 150.431 CPU sec, 4.882 real sec
[M::mem_process_seqs] Processed 672270 reads in 100.388 CPU sec, 3.247 real sec
sorting block 153, #reads = 1066621 mem = 536879795 peak = 1086410752
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 164053172
overall: 70142595072 mem 26155.017 user 566.488 sys 883.424 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1136_253-T1-TDNA-1_A23MHWWLT4_1.L001\tPU:L001\tSM:1136_253-T1-TDNA-1_A23MHWWLT4_1\tLB:1136_253-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1136_253-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1136_253-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 883.463 sec; CPU: 26721.509 sec
sorting block 154, #reads = 941138 mem = 474705879 peak = 1208549376
uniq header count 1
merging 155 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31 max 192
algo: util-sort
license: sentieon:util=1
output file size: 9561923584
output reads: 165318213
bam_mem_sort: 155 calls 84.199 user 1.310 sys 86.224 real
bam_write: 155 calls 42.080 user 2.611 sys 52.005 real
execute: 1 calls 34.900 user 1.902 sys 938.028 real
merge_files: 1 calls 34.874 user 1.880 sys 53.790 real
parse_chunk: 2479 calls 102.480 user 26.416 sys 133.803 real
read_chunk: 6693 calls 52.529 user 50.524 sys 820.517 real
sort_block: 1 calls 37.455 user 49.833 sys 797.308 real
write_chunk: 4212 calls 34.447 user 1.530 sys 52.774 real
overall: 3475836928 mem 2139.061 user 98.187 sys 938.047 real
ls: cannot access '*.cram': No such file or directory