cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1136_4ZB-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 1739.044 CPU sec, 59.841 real sec
[M::process] read 701748 sequences (100000102 bp) in 0.964 CPU sec, 0.969 real sec...
[M::process] read 700380 sequences (100000243 bp) in 1.560 CPU sec, 1.629 real sec...
[M::process] read 703306 sequences (100000031 bp) in 1.603 CPU sec, 1.647 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 287185, 16, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 316, 574)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1310)
[M::mem_pestat] mean and std.dev: (299.28, 151.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1678)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 231, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (255.98, 127.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 876)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (287, 524, 681)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1469)
[M::mem_pestat] mean and std.dev: (490.06, 264.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1863)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 272, 425)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 891)
[M::mem_pestat] mean and std.dev: (262.70, 126.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1124)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703844 sequences (100000215 bp) in 1.622 CPU sec, 1.634 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (79, 288350, 18, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 198, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1049)
[M::mem_pestat] mean and std.dev: (220.62, 174.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1350)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 227, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684)
[M::mem_pestat] mean and std.dev: (251.70, 125.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 861)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 465, 748)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1946)
[M::mem_pestat] mean and std.dev: (456.59, 314.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2545)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 295, 408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 842)
[M::mem_pestat] mean and std.dev: (265.49, 137.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1059)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 286804, 20, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 266, 510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1174)
[M::mem_pestat] mean and std.dev: (309.90, 170.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1506)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 236, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 716)
[M::mem_pestat] mean and std.dev: (260.80, 129.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 902)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (450, 621, 2873)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7719)
[M::mem_pestat] mean and std.dev: (1613.80, 1754.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10142)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 328, 929)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2313)
[M::mem_pestat] mean and std.dev: (573.53, 542.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3005)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701748 reads in 271.140 CPU sec, 8.730 real sec
[M::mem_process_seqs] Processed 703306 reads in 189.076 CPU sec, 6.100 real sec
[M::mem_process_seqs] Processed 700380 reads in 210.604 CPU sec, 6.787 real sec
sorting block 0, #reads = 1082943 mem = 536880784 peak = 614289408
[M::process] read 701066 sequences (100000054 bp) in 2.175 CPU sec, 2.308 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 288939, 25, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 261, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 724)
[M::mem_pestat] mean and std.dev: (271.95, 143.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 910)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 225, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 677)
[M::mem_pestat] mean and std.dev: (249.70, 124.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 852)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (40, 442, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1330)
[M::mem_pestat] mean and std.dev: (275.52, 207.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1760)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 269, 515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1201)
[M::mem_pestat] mean and std.dev: (269.30, 152.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1544)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702786 sequences (100000081 bp) in 1.763 CPU sec, 1.790 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (84, 287233, 15, 102)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 311, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1059)
[M::mem_pestat] mean and std.dev: (294.55, 182.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1355)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 233, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 706)
[M::mem_pestat] mean and std.dev: (258.60, 129.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 889)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (356, 463, 733)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1487)
[M::mem_pestat] mean and std.dev: (489.93, 287.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1864)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 344, 411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 883)
[M::mem_pestat] mean and std.dev: (293.80, 145.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1119)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703852 sequences (100000095 bp) in 1.609 CPU sec, 1.614 real sec...
[M::mem_process_seqs] Processed 703844 reads in 173.739 CPU sec, 5.509 real sec
sorting block 1, #reads = 1083112 mem = 536879557 peak = 799887360
[M::mem_process_seqs] Processed 701066 reads in 117.808 CPU sec, 3.869 real sec
sorting block 2, #reads = 1084366 mem = 536884046 peak = 907083776
[M::process] read 703402 sequences (100000108 bp) in 1.777 CPU sec, 1.857 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 288182, 24, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 302, 1048)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2810)
[M::mem_pestat] mean and std.dev: (551.58, 602.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3691)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (253.45, 126.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (374, 465, 962)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2138)
[M::mem_pestat] mean and std.dev: (515.10, 339.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2726)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 300, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 944)
[M::mem_pestat] mean and std.dev: (278.37, 153.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1200)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701686 sequences (100000086 bp) in 1.741 CPU sec, 1.757 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 288400, 15, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 215, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 715)
[M::mem_pestat] mean and std.dev: (238.50, 135.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 904)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 225, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (251.11, 125.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 860)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (306, 523, 1784)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4740)
[M::mem_pestat] mean and std.dev: (867.00, 767.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6218)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 271, 407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 809)
[M::mem_pestat] mean and std.dev: (250.17, 95.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1010)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 288525, 24, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 221, 919)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2465)
[M::mem_pestat] mean and std.dev: (412.19, 451.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3238)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 226, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 678)
[M::mem_pestat] mean and std.dev: (250.28, 124.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 853)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (556, 936, 938)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1702)
[M::mem_pestat] mean and std.dev: (736.21, 337.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2088)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 273, 516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1160)
[M::mem_pestat] mean and std.dev: (330.34, 214.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1482)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702786 reads in 245.906 CPU sec, 8.023 real sec
[M::mem_process_seqs] Processed 703852 reads in 194.614 CPU sec, 6.275 real sec
[M::mem_process_seqs] Processed 703402 reads in 213.774 CPU sec, 7.014 real sec
sorting block 3, #reads = 1085803 mem = 536879673 peak = 907083776
[M::process] read 701390 sequences (100000120 bp) in 2.108 CPU sec, 2.296 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 287583, 28, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 274, 492)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1156)
[M::mem_pestat] mean and std.dev: (279.61, 192.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1488)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 229, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 686)
[M::mem_pestat] mean and std.dev: (253.70, 125.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 863)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (548, 934, 3254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8666)
[M::mem_pestat] mean and std.dev: (1357.38, 1692.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11372)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 314, 590)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1388)
[M::mem_pestat] mean and std.dev: (357.27, 262.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1787)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 4, #reads = 1086156 mem = 536877984 peak = 907083776
[M::process] read 701968 sequences (100000290 bp) in 2.274 CPU sec, 2.379 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 287628, 22, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 273, 375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 793)
[M::mem_pestat] mean and std.dev: (225.45, 89.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1002)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 229, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684)
[M::mem_pestat] mean and std.dev: (253.61, 125.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 860)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 936, 1993)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5599)
[M::mem_pestat] mean and std.dev: (935.26, 959.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7402)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 277, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 723)
[M::mem_pestat] mean and std.dev: (271.93, 122.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 898)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701686 reads in 178.540 CPU sec, 5.833 real sec
[M::process] read 701326 sequences (100000024 bp) in 1.809 CPU sec, 1.874 real sec...
[M::mem_process_seqs] Processed 701390 reads in 123.335 CPU sec, 4.044 real sec
sorting block 5, #reads = 1083185 mem = 536884613 peak = 907083776
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 287524, 24, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 271, 495)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1127)
[M::mem_pestat] mean and std.dev: (299.59, 183.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1443)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 228, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (252.89, 124.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 859)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (295, 587, 818)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1864)
[M::mem_pestat] mean and std.dev: (471.15, 316.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2387)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 318, 1196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3186)
[M::mem_pestat] mean and std.dev: (543.68, 549.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4181)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701504 sequences (100000244 bp) in 2.388 CPU sec, 2.523 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 287485, 31, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 293, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1046)
[M::mem_pestat] mean and std.dev: (255.17, 116.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1340)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 229, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (252.66, 123.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 855)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (105, 324, 1118)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3144)
[M::mem_pestat] mean and std.dev: (435.56, 421.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4157)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 332, 489)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1041)
[M::mem_pestat] mean and std.dev: (329.96, 166.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1317)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699556 sequences (100000199 bp) in 1.756 CPU sec, 1.762 real sec...
[M::mem_process_seqs] Processed 701968 reads in 179.490 CPU sec, 5.830 real sec
[M::mem_process_seqs] Processed 701326 reads in 118.649 CPU sec, 3.859 real sec
sorting block 6, #reads = 1083623 mem = 536878771 peak = 907083776
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 287276, 34, 84)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 302, 483)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1063)
[M::mem_pestat] mean and std.dev: (318.92, 204.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1353)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 228, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (251.26, 122.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 847)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (56, 724, 3754)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11150)
[M::mem_pestat] mean and std.dev: (1612.38, 2231.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14848)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 292, 494)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1096)
[M::mem_pestat] mean and std.dev: (314.76, 183.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1397)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701392 sequences (100000251 bp) in 2.328 CPU sec, 2.632 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 286524, 29, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 412, 646)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1436)
[M::mem_pestat] mean and std.dev: (436.63, 267.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1831)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 234, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (257.63, 126.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (120, 530, 1578)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4494)
[M::mem_pestat] mean and std.dev: (637.81, 666.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5952)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 344, 1048)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2704)
[M::mem_pestat] mean and std.dev: (533.70, 496.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3532)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701820 sequences (100000225 bp) in 1.692 CPU sec, 1.699 real sec...
[M::mem_process_seqs] Processed 701504 reads in 177.556 CPU sec, 5.783 real sec
sorting block 7, #reads = 1083391 mem = 536882478 peak = 907083776
[M::mem_process_seqs] Processed 699556 reads in 116.919 CPU sec, 3.801 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 287532, 16, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 237, 524)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1220)
[M::mem_pestat] mean and std.dev: (307.51, 198.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1568)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 228, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 672)
[M::mem_pestat] mean and std.dev: (251.38, 122.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 844)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (267, 720, 1036)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2574)
[M::mem_pestat] mean and std.dev: (686.27, 612.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3343)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 335, 588)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1312)
[M::mem_pestat] mean and std.dev: (361.66, 170.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1674)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 8, #reads = 1082565 mem = 536880188 peak = 907083776
[M::process] read 700950 sequences (100000097 bp) in 2.451 CPU sec, 2.633 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 287937, 13, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 251, 411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 901)
[M::mem_pestat] mean and std.dev: (277.90, 159.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1146)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 228, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (250.88, 122.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 843)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 543, 1741)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4885)
[M::mem_pestat] mean and std.dev: (921.62, 943.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6457)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 279, 503)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1157)
[M::mem_pestat] mean and std.dev: (295.72, 205.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1484)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701792 sequences (100000125 bp) in 1.781 CPU sec, 1.790 real sec...
[M::mem_process_seqs] Processed 701392 reads in 177.041 CPU sec, 5.752 real sec
[M::mem_process_seqs] Processed 701820 reads in 117.450 CPU sec, 3.820 real sec
sorting block 9, #reads = 1083391 mem = 536879903 peak = 907083776
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 287361, 18, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 257, 481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1099)
[M::mem_pestat] mean and std.dev: (304.30, 205.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1408)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 230, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 681)
[M::mem_pestat] mean and std.dev: (253.25, 123.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 856)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 814, 1487)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4103)
[M::mem_pestat] mean and std.dev: (876.53, 851.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5411)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 326, 726)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1812)
[M::mem_pestat] mean and std.dev: (493.80, 428.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2355)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700672 sequences (100000196 bp) in 2.422 CPU sec, 2.728 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 287686, 23, 84)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 372, 633)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1485)
[M::mem_pestat] mean and std.dev: (417.90, 283.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1911)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 228, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (252.13, 124.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 855)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (87, 367, 1089)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3093)
[M::mem_pestat] mean and std.dev: (554.05, 624.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4095)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 289, 512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1078)
[M::mem_pestat] mean and std.dev: (362.73, 234.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1361)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702534 sequences (100000065 bp) in 1.661 CPU sec, 1.686 real sec...
[M::mem_process_seqs] Processed 700950 reads in 180.160 CPU sec, 5.895 real sec
[M::mem_process_seqs] Processed 701792 reads in 118.490 CPU sec, 3.875 real sec
sorting block 10, #reads = 1083012 mem = 536881747 peak = 907083776
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 287325, 19, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 302, 905)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2407)
[M::mem_pestat] mean and std.dev: (359.53, 342.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3158)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 233, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (257.52, 127.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 881)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 643, 1721)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4717)
[M::mem_pestat] mean and std.dev: (884.44, 967.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6215)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 321, 598)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1376)
[M::mem_pestat] mean and std.dev: (339.08, 213.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1765)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700942 sequences (100000260 bp) in 2.517 CPU sec, 2.947 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 287876, 20, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 250, 741)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1925)
[M::mem_pestat] mean and std.dev: (380.56, 380.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2517)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 228, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (251.64, 123.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 855)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (354, 758, 1033)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2391)
[M::mem_pestat] mean and std.dev: (730.17, 461.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3070)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 364, 647)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1553)
[M::mem_pestat] mean and std.dev: (412.31, 325.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2006)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702208 sequences (100000121 bp) in 1.846 CPU sec, 1.927 real sec...
[M::mem_process_seqs] Processed 700672 reads in 180.037 CPU sec, 5.901 real sec
[M::mem_process_seqs] Processed 702534 reads in 116.622 CPU sec, 3.825 real sec
sorting block 11, #reads = 1083846 mem = 536879190 peak = 907083776
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 286934, 17, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 345, 648)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1666)
[M::mem_pestat] mean and std.dev: (399.28, 328.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2175)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 234, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 706)
[M::mem_pestat] mean and std.dev: (258.40, 128.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 889)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (297, 482, 1629)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4293)
[M::mem_pestat] mean and std.dev: (758.35, 640.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5625)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 238, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 965)
[M::mem_pestat] mean and std.dev: (259.89, 157.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1230)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 12, #reads = 1082932 mem = 536884746 peak = 907083776
[M::process] read 701994 sequences (100000127 bp) in 2.592 CPU sec, 2.870 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 288198, 20, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 244, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1107)
[M::mem_pestat] mean and std.dev: (285.12, 173.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1425)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 230, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (255.20, 127.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 875)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (66, 644, 898)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2562)
[M::mem_pestat] mean and std.dev: (645.10, 612.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3394)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 301, 653)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1573)
[M::mem_pestat] mean and std.dev: (390.85, 265.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2033)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702254 sequences (100000164 bp) in 1.712 CPU sec, 1.809 real sec...
[M::mem_process_seqs] Processed 700942 reads in 175.445 CPU sec, 5.715 real sec
[M::mem_process_seqs] Processed 702208 reads in 114.785 CPU sec, 3.740 real sec
sorting block 13, #reads = 1084694 mem = 536881622 peak = 907083776
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 287560, 19, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 239, 542)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1230)
[M::mem_pestat] mean and std.dev: (292.52, 180.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1574)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 230, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (254.92, 126.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 875)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (688, 751, 1201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2227)
[M::mem_pestat] mean and std.dev: (828.44, 380.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2740)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 298, 708)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1712)
[M::mem_pestat] mean and std.dev: (395.96, 342.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2214)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701978 sequences (100000179 bp) in 2.646 CPU sec, 2.875 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 287334, 25, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 211, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 776)
[M::mem_pestat] mean and std.dev: (262.59, 173.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 980)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 230, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (254.77, 126.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 875)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 431, 914)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2288)
[M::mem_pestat] mean and std.dev: (515.22, 386.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2975)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 303, 515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1103)
[M::mem_pestat] mean and std.dev: (315.70, 200.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1397)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702388 sequences (100000114 bp) in 1.831 CPU sec, 1.840 real sec...
[M::mem_process_seqs] Processed 701994 reads in 177.246 CPU sec, 5.781 real sec
[M::mem_process_seqs] Processed 702254 reads in 118.838 CPU sec, 3.887 real sec
sorting block 14, #reads = 1086183 mem = 536878259 peak = 907083776
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 287948, 10, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 291, 650)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1636)
[M::mem_pestat] mean and std.dev: (324.59, 245.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2129)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 230, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (255.19, 126.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (379, 811, 3892)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10918)
[M::mem_pestat] mean and std.dev: (1812.00, 1985.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14431)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 305, 826)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2076)
[M::mem_pestat] mean and std.dev: (372.54, 331.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2701)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702616 sequences (100000172 bp) in 2.624 CPU sec, 2.855 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 287797, 26, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 263, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 650)
[M::mem_pestat] mean and std.dev: (221.78, 84.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 806)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (252.57, 125.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 636, 1159)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3131)
[M::mem_pestat] mean and std.dev: (639.44, 543.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4117)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 261, 479)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1061)
[M::mem_pestat] mean and std.dev: (317.93, 189.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1352)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700978 sequences (100000283 bp) in 1.648 CPU sec, 1.661 real sec...
[M::mem_process_seqs] Processed 701978 reads in 176.164 CPU sec, 5.742 real sec
[M::mem_process_seqs] Processed 702388 reads in 119.573 CPU sec, 3.886 real sec
sorting block 15, #reads = 1085854 mem = 536879784 peak = 907083776
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (90, 288126, 14, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 276, 521)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1175)
[M::mem_pestat] mean and std.dev: (357.50, 237.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1502)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 229, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (252.99, 125.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (721, 918, 2191)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5131)
[M::mem_pestat] mean and std.dev: (1246.38, 956.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6601)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 331, 538)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1126)
[M::mem_pestat] mean and std.dev: (375.75, 201.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1420)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699980 sequences (100000188 bp) in 2.692 CPU sec, 3.066 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 287527, 14, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 258, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 606)
[M::mem_pestat] mean and std.dev: (247.69, 112.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 753)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 232, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 694)
[M::mem_pestat] mean and std.dev: (256.27, 126.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 873)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 490, 863)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2229)
[M::mem_pestat] mean and std.dev: (517.23, 451.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2912)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 311, 902)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2334)
[M::mem_pestat] mean and std.dev: (444.59, 382.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3050)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702616 reads in 171.783 CPU sec, 5.592 real sec
sorting block 16, #reads = 1085210 mem = 536878526 peak = 907083776
[M::process] read 701722 sequences (100000078 bp) in 2.034 CPU sec, 2.106 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 286761, 31, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 193, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 669)
[M::mem_pestat] mean and std.dev: (206.43, 110.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 842)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 234, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701)
[M::mem_pestat] mean and std.dev: (258.27, 127.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 882)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (780, 827, 884)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (572, 1092)
[M::mem_pestat] mean and std.dev: (810.15, 87.99)
[M::mem_pestat] low and high boundaries for proper pairs: (458, 1196)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 291, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1025)
[M::mem_pestat] mean and std.dev: (303.86, 160.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1303)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702226 sequences (100000187 bp) in 2.112 CPU sec, 2.141 real sec...
[M::mem_process_seqs] Processed 699980 reads in 94.970 CPU sec, 3.033 real sec
sorting block 17, #reads = 1083913 mem = 536879731 peak = 922959872
[M::mem_process_seqs] Processed 700978 reads in 254.849 CPU sec, 8.134 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 288013, 31, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 267, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 816)
[M::mem_pestat] mean and std.dev: (272.14, 142.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1039)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 228, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (251.84, 123.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 855)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (82, 351, 562)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1522)
[M::mem_pestat] mean and std.dev: (309.26, 303.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2002)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 330, 752)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1862)
[M::mem_pestat] mean and std.dev: (434.12, 363.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2417)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702304 sequences (100000155 bp) in 2.701 CPU sec, 2.984 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 287898, 19, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 264, 941)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2461)
[M::mem_pestat] mean and std.dev: (397.54, 416.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3221)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (251.45, 123.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (130, 160, 434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1042)
[M::mem_pestat] mean and std.dev: (289.95, 280.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1413)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 336, 525)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1151)
[M::mem_pestat] mean and std.dev: (346.88, 208.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1464)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701722 reads in 194.574 CPU sec, 6.272 real sec
sorting block 18, #reads = 1085242 mem = 536878961 peak = 922959872
[M::mem_process_seqs] Processed 702226 reads in 118.728 CPU sec, 3.836 real sec
[M::process] read 699592 sequences (100000139 bp) in 1.826 CPU sec, 1.918 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 287748, 16, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 265, 775)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1983)
[M::mem_pestat] mean and std.dev: (366.50, 292.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2587)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 676)
[M::mem_pestat] mean and std.dev: (250.78, 123.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 850)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 926, 1843)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5199)
[M::mem_pestat] mean and std.dev: (1013.94, 911.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6877)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 367, 513)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1057)
[M::mem_pestat] mean and std.dev: (350.93, 167.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1329)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 19, #reads = 1084432 mem = 536883481 peak = 930394112
[M::process] read 702000 sequences (100000198 bp) in 2.897 CPU sec, 3.127 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 287549, 26, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (123, 225, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 732)
[M::mem_pestat] mean and std.dev: (222.24, 107.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 935)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 235, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (257.53, 125.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (267, 621, 893)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2145)
[M::mem_pestat] mean and std.dev: (562.62, 348.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2771)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 312, 721)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1725)
[M::mem_pestat] mean and std.dev: (388.03, 286.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2227)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702304 reads in 175.347 CPU sec, 5.651 real sec
[M::process] read 702022 sequences (100000093 bp) in 1.831 CPU sec, 1.906 real sec...
[M::mem_process_seqs] Processed 699592 reads in 118.379 CPU sec, 3.939 real sec
sorting block 20, #reads = 1084063 mem = 536880979 peak = 930394112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 287455, 21, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 315, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 896)
[M::mem_pestat] mean and std.dev: (289.14, 141.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1124)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 228, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (251.36, 123.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 847)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (33, 258, 1428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4218)
[M::mem_pestat] mean and std.dev: (635.24, 864.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5613)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 272, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 940)
[M::mem_pestat] mean and std.dev: (285.86, 153.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1191)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702270 sequences (100000140 bp) in 2.517 CPU sec, 2.806 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 287743, 17, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 300, 631)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1575)
[M::mem_pestat] mean and std.dev: (378.72, 285.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2047)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 227, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (250.67, 122.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 847)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 661, 3133)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8931)
[M::mem_pestat] mean and std.dev: (917.60, 1126.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11830)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 225, 992)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2666)
[M::mem_pestat] mean and std.dev: (505.21, 552.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3503)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703192 sequences (100000075 bp) in 1.665 CPU sec, 1.665 real sec...
[M::mem_process_seqs] Processed 702000 reads in 177.753 CPU sec, 5.933 real sec
[M::mem_process_seqs] Processed 702022 reads in 121.024 CPU sec, 4.038 real sec
sorting block 21, #reads = 1083412 mem = 536877802 peak = 930394112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 288253, 14, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 286, 763)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1975)
[M::mem_pestat] mean and std.dev: (364.60, 321.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2581)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 227, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (250.90, 123.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 847)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (51, 428, 1452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4254)
[M::mem_pestat] mean and std.dev: (553.92, 617.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5655)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 273, 476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 952)
[M::mem_pestat] mean and std.dev: (326.76, 153.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1190)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702536 sequences (100000129 bp) in 2.521 CPU sec, 2.706 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 288240, 22, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 288, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1019)
[M::mem_pestat] mean and std.dev: (313.62, 186.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1302)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 226, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 675)
[M::mem_pestat] mean and std.dev: (250.08, 123.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 849)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (109, 462, 940)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2602)
[M::mem_pestat] mean and std.dev: (572.81, 613.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3433)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 318, 514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1112)
[M::mem_pestat] mean and std.dev: (329.25, 197.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1411)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702592 sequences (100000162 bp) in 1.884 CPU sec, 1.886 real sec...
[M::mem_process_seqs] Processed 702270 reads in 180.623 CPU sec, 5.948 real sec
sorting block 22, #reads = 1084180 mem = 536883225 peak = 930394112
[M::mem_process_seqs] Processed 703192 reads in 120.351 CPU sec, 3.937 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 286922, 24, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 327, 1111)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2969)
[M::mem_pestat] mean and std.dev: (429.16, 449.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3898)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 676)
[M::mem_pestat] mean and std.dev: (250.82, 123.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 850)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (354, 569, 1425)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3567)
[M::mem_pestat] mean and std.dev: (740.96, 590.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4638)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 281, 396)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 808)
[M::mem_pestat] mean and std.dev: (259.20, 127.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1014)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 23, #reads = 1084570 mem = 536886338 peak = 943288320
[M::process] read 702818 sequences (100000061 bp) in 2.589 CPU sec, 2.939 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 287382, 18, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 323, 588)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1306)
[M::mem_pestat] mean and std.dev: (402.09, 239.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1665)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 229, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (252.22, 123.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 862)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (783, 1223, 1686)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3492)
[M::mem_pestat] mean and std.dev: (1119.69, 576.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4395)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 237, 650)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1586)
[M::mem_pestat] mean and std.dev: (340.60, 310.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2054)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701998 sequences (100000245 bp) in 1.903 CPU sec, 2.037 real sec...
[M::mem_process_seqs] Processed 702536 reads in 185.977 CPU sec, 6.090 real sec
[M::mem_process_seqs] Processed 702592 reads in 125.122 CPU sec, 4.079 real sec
sorting block 24, #reads = 1081922 mem = 536878810 peak = 943288320
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 287698, 24, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 322, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 911)
[M::mem_pestat] mean and std.dev: (327.81, 166.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1148)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (251.40, 123.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 286, 1764)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4864)
[M::mem_pestat] mean and std.dev: (942.09, 1284.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6414)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 269, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 928)
[M::mem_pestat] mean and std.dev: (296.02, 144.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1170)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699768 sequences (100000039 bp) in 2.415 CPU sec, 2.736 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 287510, 30, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 209, 507)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1217)
[M::mem_pestat] mean and std.dev: (274.18, 169.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1572)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 231, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (254.81, 125.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (31, 449, 476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1366)
[M::mem_pestat] mean and std.dev: (330.85, 271.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1811)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 296, 487)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1097)
[M::mem_pestat] mean and std.dev: (324.42, 217.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1402)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702690 sequences (100000292 bp) in 2.051 CPU sec, 2.097 real sec...
[M::mem_process_seqs] Processed 702818 reads in 182.801 CPU sec, 5.962 real sec
[M::mem_process_seqs] Processed 701998 reads in 121.923 CPU sec, 3.980 real sec
sorting block 25, #reads = 1083657 mem = 536878159 peak = 943288320
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 287155, 17, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 346, 682)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1662)
[M::mem_pestat] mean and std.dev: (531.26, 485.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2473)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 238, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 723)
[M::mem_pestat] mean and std.dev: (262.72, 130.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 911)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (277, 437, 1639)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4363)
[M::mem_pestat] mean and std.dev: (929.53, 1025.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5725)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 319, 778)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1898)
[M::mem_pestat] mean and std.dev: (426.59, 422.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2458)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703288 sequences (100000133 bp) in 2.461 CPU sec, 2.679 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 287956, 24, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 259, 663)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1663)
[M::mem_pestat] mean and std.dev: (305.02, 239.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2163)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 229, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (252.69, 124.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 862)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (29, 190, 687)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2003)
[M::mem_pestat] mean and std.dev: (345.91, 355.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2661)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (300, 507, 1065)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2595)
[M::mem_pestat] mean and std.dev: (644.53, 467.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3360)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702694 sequences (100000097 bp) in 1.725 CPU sec, 1.734 real sec...
[M::mem_process_seqs] Processed 699768 reads in 180.217 CPU sec, 5.888 real sec
[M::mem_process_seqs] Processed 702690 reads in 120.296 CPU sec, 3.867 real sec
sorting block 26, #reads = 1083810 mem = 536882457 peak = 943288320
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 288544, 15, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (246, 349, 1109)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2835)
[M::mem_pestat] mean and std.dev: (480.28, 435.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3698)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 227, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (251.84, 125.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 865)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (589, 670, 875)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (17, 1447)
[M::mem_pestat] mean and std.dev: (662.36, 270.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1745)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 363, 1021)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2691)
[M::mem_pestat] mean and std.dev: (544.05, 542.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3526)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 27, #reads = 1083909 mem = 536879092 peak = 946565120
[M::process] read 702892 sequences (100000157 bp) in 2.590 CPU sec, 3.146 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 287766, 19, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 281, 577)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1393)
[M::mem_pestat] mean and std.dev: (364.08, 313.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1801)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 229, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (252.38, 124.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 862)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (475, 1071, 2801)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7453)
[M::mem_pestat] mean and std.dev: (1407.71, 1370.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9779)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 306, 572)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1388)
[M::mem_pestat] mean and std.dev: (365.70, 261.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1796)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701544 sequences (100000025 bp) in 1.894 CPU sec, 1.898 real sec...
[M::mem_process_seqs] Processed 703288 reads in 176.425 CPU sec, 5.748 real sec
[M::mem_process_seqs] Processed 702694 reads in 120.717 CPU sec, 4.022 real sec
sorting block 28, #reads = 1086429 mem = 536884411 peak = 946565120
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 288380, 15, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 247, 483)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1115)
[M::mem_pestat] mean and std.dev: (279.30, 191.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1431)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (251.85, 124.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (353, 609, 3900)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10994)
[M::mem_pestat] mean and std.dev: (1601.67, 1786.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14541)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 319, 492)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1080)
[M::mem_pestat] mean and std.dev: (331.29, 167.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1374)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699870 sequences (100000257 bp) in 2.563 CPU sec, 2.962 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (79, 287415, 39, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 296, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 896)
[M::mem_pestat] mean and std.dev: (265.63, 118.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1129)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 231, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (256.08, 126.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 880)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (550, 836, 1175)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2425)
[M::mem_pestat] mean and std.dev: (697.52, 417.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3050)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 365, 638)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1546)
[M::mem_pestat] mean and std.dev: (459.50, 364.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2000)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701876 sequences (100000275 bp) in 1.691 CPU sec, 1.700 real sec...
[M::mem_process_seqs] Processed 702892 reads in 178.080 CPU sec, 5.913 real sec
[M::mem_process_seqs] Processed 701544 reads in 118.637 CPU sec, 3.886 real sec
sorting block 29, #reads = 1084800 mem = 536888002 peak = 946565120
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 286838, 27, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 358, 678)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1652)
[M::mem_pestat] mean and std.dev: (312.63, 211.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2139)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 236, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 702)
[M::mem_pestat] mean and std.dev: (259.43, 127.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 883)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 1355, 4098)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11866)
[M::mem_pestat] mean and std.dev: (2090.19, 1723.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 15750)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 389, 591)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1295)
[M::mem_pestat] mean and std.dev: (404.96, 232.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1647)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701882 sequences (100000076 bp) in 2.601 CPU sec, 2.907 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 287486, 26, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 254, 689)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1733)
[M::mem_pestat] mean and std.dev: (343.56, 284.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2255)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 229, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (252.65, 124.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 855)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 706, 1182)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3070)
[M::mem_pestat] mean and std.dev: (726.60, 485.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4014)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (269, 375, 927)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2243)
[M::mem_pestat] mean and std.dev: (555.03, 445.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2901)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701800 sequences (100000236 bp) in 1.847 CPU sec, 1.866 real sec...
[M::mem_process_seqs] Processed 699870 reads in 179.618 CPU sec, 5.841 real sec
sorting block 30, #reads = 1083719 mem = 536879482 peak = 946565120
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 287742, 23, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 206, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (236.07, 137.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 229, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (252.71, 124.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 859)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (74, 248, 607)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1673)
[M::mem_pestat] mean and std.dev: (238.75, 210.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2206)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 261, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 975)
[M::mem_pestat] mean and std.dev: (314.27, 176.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1228)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702082 sequences (100000089 bp) in 2.030 CPU sec, 2.048 real sec...
[M::mem_process_seqs] Processed 701882 reads in 105.726 CPU sec, 3.440 real sec
[M::mem_process_seqs] Processed 701876 reads in 265.314 CPU sec, 8.572 real sec
sorting block 31, #reads = 1085043 mem = 536879167 peak = 946565120
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 287271, 14, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 269, 530)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1266)
[M::mem_pestat] mean and std.dev: (325.23, 229.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1634)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 228, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 677)
[M::mem_pestat] mean and std.dev: (251.73, 123.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 851)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 443, 1360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3788)
[M::mem_pestat] mean and std.dev: (739.46, 890.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5002)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 365, 943)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2375)
[M::mem_pestat] mean and std.dev: (512.45, 491.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3091)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702572 sequences (100000097 bp) in 2.487 CPU sec, 2.958 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 287734, 23, 81)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 239, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 738)
[M::mem_pestat] mean and std.dev: (223.40, 98.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 932)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 673)
[M::mem_pestat] mean and std.dev: (250.30, 122.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 846)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 434, 777)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1957)
[M::mem_pestat] mean and std.dev: (468.91, 327.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2547)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 301, 398)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 794)
[M::mem_pestat] mean and std.dev: (292.11, 150.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 992)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701800 reads in 202.004 CPU sec, 6.514 real sec
[M::mem_process_seqs] Processed 702082 reads in 125.798 CPU sec, 4.039 real sec
[M::process] read 701978 sequences (100000245 bp) in 2.113 CPU sec, 2.221 real sec...
sorting block 32, #reads = 1083348 mem = 536880588 peak = 946565120
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 287834, 32, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 212, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 795)
[M::mem_pestat] mean and std.dev: (239.34, 131.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1008)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 226, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 670)
[M::mem_pestat] mean and std.dev: (249.71, 122.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 842)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (109, 149, 806)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2200)
[M::mem_pestat] mean and std.dev: (361.66, 478.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2897)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 294, 433)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 933)
[M::mem_pestat] mean and std.dev: (298.02, 141.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1183)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702196 sequences (100000238 bp) in 2.362 CPU sec, 2.602 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 287502, 33, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 202, 385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 859)
[M::mem_pestat] mean and std.dev: (241.42, 151.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1096)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 227, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (250.35, 122.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 843)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (79, 496, 1299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3739)
[M::mem_pestat] mean and std.dev: (708.03, 676.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4959)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 272, 484)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1040)
[M::mem_pestat] mean and std.dev: (306.47, 165.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1318)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702296 sequences (100000156 bp) in 1.983 CPU sec, 1.999 real sec...
[M::mem_process_seqs] Processed 702572 reads in 185.982 CPU sec, 5.974 real sec
sorting block 33, #reads = 1084166 mem = 536884333 peak = 946565120
[M::mem_process_seqs] Processed 701978 reads in 124.171 CPU sec, 4.010 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (88, 287724, 19, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 335, 592)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1364)
[M::mem_pestat] mean and std.dev: (350.25, 199.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1750)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 226, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 670)
[M::mem_pestat] mean and std.dev: (249.85, 122.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 842)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (426, 475, 1145)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2583)
[M::mem_pestat] mean and std.dev: (730.47, 556.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3302)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 264, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 706)
[M::mem_pestat] mean and std.dev: (266.68, 111.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 877)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 34, #reads = 1084427 mem = 536878644 peak = 995684352
[M::process] read 702480 sequences (100000162 bp) in 2.543 CPU sec, 2.952 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 287797, 18, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 216, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 777)
[M::mem_pestat] mean and std.dev: (225.89, 121.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 986)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 676)
[M::mem_pestat] mean and std.dev: (251.07, 123.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 850)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 1474, 3836)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11060)
[M::mem_pestat] mean and std.dev: (2598.78, 3138.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 15154)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 319, 656)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1560)
[M::mem_pestat] mean and std.dev: (405.42, 337.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2012)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702196 reads in 180.221 CPU sec, 5.895 real sec
[M::process] read 699188 sequences (100000100 bp) in 2.295 CPU sec, 2.412 real sec...
[M::mem_process_seqs] Processed 702296 reads in 125.642 CPU sec, 4.120 real sec
sorting block 35, #reads = 1084674 mem = 536879700 peak = 995684352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 287396, 21, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 345, 549)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1239)
[M::mem_pestat] mean and std.dev: (349.71, 204.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1584)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (251.62, 124.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (523, 1010, 2440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6274)
[M::mem_pestat] mean and std.dev: (1502.29, 1162.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8191)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 245, 428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 926)
[M::mem_pestat] mean and std.dev: (279.94, 153.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1175)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699858 sequences (100000092 bp) in 2.255 CPU sec, 2.535 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 286253, 24, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 262, 555)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1353)
[M::mem_pestat] mean and std.dev: (363.59, 305.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1752)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 237, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 703)
[M::mem_pestat] mean and std.dev: (259.63, 126.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 884)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (127, 408, 912)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2482)
[M::mem_pestat] mean and std.dev: (383.29, 357.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3267)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 227, 392)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 876)
[M::mem_pestat] mean and std.dev: (267.82, 183.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1118)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700926 sequences (100000045 bp) in 2.024 CPU sec, 2.038 real sec...
[M::mem_process_seqs] Processed 702480 reads in 184.959 CPU sec, 6.088 real sec
[M::mem_process_seqs] Processed 699188 reads in 122.380 CPU sec, 3.980 real sec
sorting block 36, #reads = 1082393 mem = 536877509 peak = 995684352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 287065, 27, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 256, 500)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1210)
[M::mem_pestat] mean and std.dev: (324.25, 226.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1565)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 236, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (258.09, 125.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 878)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (270, 299, 591)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1233)
[M::mem_pestat] mean and std.dev: (348.52, 207.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1554)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 281, 425)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 891)
[M::mem_pestat] mean and std.dev: (280.66, 118.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1124)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699148 sequences (100000160 bp) in 2.342 CPU sec, 2.858 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 287198, 37, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 242, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1048)
[M::mem_pestat] mean and std.dev: (294.51, 208.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1345)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 233, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (254.39, 123.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 865)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 256, 534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1242)
[M::mem_pestat] mean and std.dev: (246.23, 118.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1596)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 274, 1062)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2786)
[M::mem_pestat] mean and std.dev: (570.55, 535.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3648)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699858 reads in 169.552 CPU sec, 5.618 real sec
[M::mem_process_seqs] Processed 700926 reads in 119.841 CPU sec, 3.871 real sec
[M::process] read 701318 sequences (100000249 bp) in 2.243 CPU sec, 2.322 real sec...
sorting block 37, #reads = 1082788 mem = 536879382 peak = 995684352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 286434, 19, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 296, 791)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2007)
[M::mem_pestat] mean and std.dev: (435.28, 376.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2615)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 238, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 714)
[M::mem_pestat] mean and std.dev: (261.37, 128.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 899)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (544, 1127, 1539)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3529)
[M::mem_pestat] mean and std.dev: (1205.78, 941.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4970)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 298, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 673)
[M::mem_pestat] mean and std.dev: (265.70, 115.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 840)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 38, #reads = 1083937 mem = 536884637 peak = 1008693248
[M::process] read 703356 sequences (100000033 bp) in 2.404 CPU sec, 2.703 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 287418, 18, 94)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 323, 704)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1668)
[M::mem_pestat] mean and std.dev: (402.69, 305.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2150)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 232, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 702)
[M::mem_pestat] mean and std.dev: (256.47, 126.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 884)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (426, 721, 1306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3066)
[M::mem_pestat] mean and std.dev: (608.29, 336.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3946)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 355, 619)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1423)
[M::mem_pestat] mean and std.dev: (378.23, 256.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1825)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699148 reads in 169.376 CPU sec, 5.512 real sec
[M::process] read 703730 sequences (100000063 bp) in 1.804 CPU sec, 1.874 real sec...
[M::mem_process_seqs] Processed 701318 reads in 127.982 CPU sec, 4.152 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 288116, 33, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 212, 507)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1243)
[M::mem_pestat] mean and std.dev: (295.02, 235.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1611)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (252.61, 125.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 266, 936)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2358)
[M::mem_pestat] mean and std.dev: (517.82, 480.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3069)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 252, 382)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 752)
[M::mem_pestat] mean and std.dev: (268.58, 107.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 937)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 39, #reads = 1082052 mem = 536882345 peak = 1008693248
[M::process] read 703684 sequences (100000294 bp) in 2.616 CPU sec, 2.855 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 287955, 44, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 246, 842)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2246)
[M::mem_pestat] mean and std.dev: (481.48, 490.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2948)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 226, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 678)
[M::mem_pestat] mean and std.dev: (249.57, 123.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 853)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (407, 1061, 3025)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8261)
[M::mem_pestat] mean and std.dev: (1510.45, 1492.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10879)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 323, 1003)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2657)
[M::mem_pestat] mean and std.dev: (495.63, 454.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3484)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703356 reads in 175.044 CPU sec, 5.667 real sec
[M::process] read 702784 sequences (100000016 bp) in 1.770 CPU sec, 1.843 real sec...
[M::mem_process_seqs] Processed 703730 reads in 119.888 CPU sec, 4.137 real sec
sorting block 40, #reads = 1085756 mem = 536878652 peak = 1008693248
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 288766, 25, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 284, 489)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1137)
[M::mem_pestat] mean and std.dev: (338.76, 260.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1461)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 225, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 678)
[M::mem_pestat] mean and std.dev: (249.82, 123.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 853)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (602, 1355, 1932)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4592)
[M::mem_pestat] mean and std.dev: (1178.76, 781.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5922)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 337, 415)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 907)
[M::mem_pestat] mean and std.dev: (290.73, 155.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1153)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700408 sequences (100000212 bp) in 2.549 CPU sec, 2.833 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 287984, 19, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 285, 604)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1498)
[M::mem_pestat] mean and std.dev: (376.41, 267.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1945)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (252.40, 124.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 862)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 329, 1072)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2868)
[M::mem_pestat] mean and std.dev: (646.42, 709.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3766)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 290, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 974)
[M::mem_pestat] mean and std.dev: (305.04, 144.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1239)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702482 sequences (100000271 bp) in 1.817 CPU sec, 1.822 real sec...
[M::mem_process_seqs] Processed 703684 reads in 179.770 CPU sec, 6.091 real sec
[M::mem_process_seqs] Processed 702784 reads in 119.363 CPU sec, 3.870 real sec
sorting block 41, #reads = 1085534 mem = 536882391 peak = 1008693248
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 286273, 22, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 218, 265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 511)
[M::mem_pestat] mean and std.dev: (204.72, 78.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 634)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 704)
[M::mem_pestat] mean and std.dev: (258.65, 127.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 886)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (398, 1504, 4089)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11471)
[M::mem_pestat] mean and std.dev: (2293.00, 2495.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 15162)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 237, 675)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1747)
[M::mem_pestat] mean and std.dev: (305.25, 224.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2283)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 42, #reads = 1084911 mem = 536880446 peak = 1008693248
[M::process] read 701518 sequences (100000038 bp) in 2.837 CPU sec, 3.126 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 288389, 14, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 318, 1032)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2648)
[M::mem_pestat] mean and std.dev: (444.29, 335.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3456)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (252.23, 124.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 377, 2434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7006)
[M::mem_pestat] mean and std.dev: (491.36, 685.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9292)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 300, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1026)
[M::mem_pestat] mean and std.dev: (281.23, 148.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1315)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702032 sequences (100000117 bp) in 1.735 CPU sec, 1.760 real sec...
[M::mem_process_seqs] Processed 700408 reads in 182.828 CPU sec, 6.021 real sec
[M::mem_process_seqs] Processed 702482 reads in 120.976 CPU sec, 3.971 real sec
sorting block 43, #reads = 1084410 mem = 536879468 peak = 1008693248
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 287197, 30, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 254, 643)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1495)
[M::mem_pestat] mean and std.dev: (399.16, 346.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1921)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 232, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (256.10, 126.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 876)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (454, 773, 1841)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4615)
[M::mem_pestat] mean and std.dev: (1065.79, 930.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6002)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 250, 550)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1362)
[M::mem_pestat] mean and std.dev: (301.83, 230.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1768)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702320 sequences (100000196 bp) in 2.747 CPU sec, 3.008 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 287188, 19, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 331, 585)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1395)
[M::mem_pestat] mean and std.dev: (350.38, 227.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1800)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 228, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (252.10, 124.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 855)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (361, 965, 3023)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8347)
[M::mem_pestat] mean and std.dev: (1589.42, 1862.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11009)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 243, 393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 817)
[M::mem_pestat] mean and std.dev: (247.50, 107.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1029)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702340 sequences (100000226 bp) in 1.926 CPU sec, 1.935 real sec...
[M::mem_process_seqs] Processed 701518 reads in 185.395 CPU sec, 6.026 real sec
[M::mem_process_seqs] Processed 702032 reads in 123.696 CPU sec, 4.009 real sec
sorting block 44, #reads = 1084962 mem = 536877085 peak = 1008693248
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 287776, 25, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 301, 379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (276.28, 133.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 955)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 228, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (250.68, 122.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 847)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 598, 927)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2443)
[M::mem_pestat] mean and std.dev: (676.68, 555.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3201)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 312, 544)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1188)
[M::mem_pestat] mean and std.dev: (374.30, 238.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1510)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702902 sequences (100000007 bp) in 2.588 CPU sec, 2.791 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 287351, 20, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 231, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 787)
[M::mem_pestat] mean and std.dev: (238.19, 122.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 996)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 226, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 670)
[M::mem_pestat] mean and std.dev: (249.50, 121.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 842)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (334, 532, 1191)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2905)
[M::mem_pestat] mean and std.dev: (658.05, 475.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3762)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 248, 530)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1158)
[M::mem_pestat] mean and std.dev: (338.26, 186.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1472)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702320 reads in 188.076 CPU sec, 6.102 real sec
[M::process] read 702470 sequences (100000021 bp) in 1.817 CPU sec, 1.845 real sec...
sorting block 45, #reads = 1083557 mem = 536878722 peak = 1008693248
[M::mem_process_seqs] Processed 702340 reads in 124.565 CPU sec, 4.267 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 288117, 16, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 261, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1071)
[M::mem_pestat] mean and std.dev: (337.33, 280.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1460)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 225, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (248.40, 121.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 631, 3005)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8555)
[M::mem_pestat] mean and std.dev: (1827.38, 2120.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11330)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 286, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1090)
[M::mem_pestat] mean and std.dev: (327.81, 219.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1399)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702526 sequences (100000265 bp) in 2.745 CPU sec, 2.980 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 287658, 19, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 304, 504)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1210)
[M::mem_pestat] mean and std.dev: (335.63, 253.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1563)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 226, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 673)
[M::mem_pestat] mean and std.dev: (249.91, 123.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 846)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 933, 1082)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2818)
[M::mem_pestat] mean and std.dev: (755.39, 685.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3686)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 302, 388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 716)
[M::mem_pestat] mean and std.dev: (281.91, 116.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 880)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705926 sequences (100000041 bp) in 1.840 CPU sec, 1.849 real sec...
[M::mem_process_seqs] Processed 702902 reads in 185.604 CPU sec, 6.209 real sec
sorting block 46, #reads = 1083103 mem = 536881407 peak = 1008693248
[M::mem_process_seqs] Processed 702470 reads in 120.758 CPU sec, 3.916 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 287871, 15, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 208, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 796)
[M::mem_pestat] mean and std.dev: (244.77, 157.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1012)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 226, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 670)
[M::mem_pestat] mean and std.dev: (249.65, 122.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 842)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (811, 1608, 3316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8326)
[M::mem_pestat] mean and std.dev: (2324.93, 2227.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11235)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 318, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 898)
[M::mem_pestat] mean and std.dev: (319.11, 135.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1132)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 47, #reads = 1084724 mem = 536877450 peak = 1011273728
[M::process] read 704682 sequences (100000271 bp) in 2.677 CPU sec, 2.912 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 288661, 18, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 277, 768)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1982)
[M::mem_pestat] mean and std.dev: (459.70, 458.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2589)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 217, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 647)
[M::mem_pestat] mean and std.dev: (241.76, 119.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 813)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (91, 212, 391)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 991)
[M::mem_pestat] mean and std.dev: (196.27, 173.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1291)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 376, 918)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2406)
[M::mem_pestat] mean and std.dev: (559.06, 509.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3150)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705972 sequences (100000131 bp) in 1.879 CPU sec, 1.918 real sec...
[M::mem_process_seqs] Processed 702526 reads in 196.045 CPU sec, 6.390 real sec
[M::mem_process_seqs] Processed 705926 reads in 129.664 CPU sec, 4.147 real sec
sorting block 48, #reads = 1082339 mem = 536878410 peak = 1011273728
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 288674, 17, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 304, 958)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2494)
[M::mem_pestat] mean and std.dev: (433.81, 380.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3262)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 222, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (249.54, 126.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 855)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (429, 902, 6561)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 18825)
[M::mem_pestat] mean and std.dev: (2138.59, 2518.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 24957)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 251, 395)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 807)
[M::mem_pestat] mean and std.dev: (270.69, 138.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1013)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706674 sequences (100000234 bp) in 2.572 CPU sec, 2.887 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 289427, 19, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 201, 376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 858)
[M::mem_pestat] mean and std.dev: (245.45, 161.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1099)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 219, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 662)
[M::mem_pestat] mean and std.dev: (244.68, 122.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 833)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (714, 871, 4091)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10845)
[M::mem_pestat] mean and std.dev: (1763.68, 1608.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14222)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 275, 500)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1196)
[M::mem_pestat] mean and std.dev: (328.65, 234.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1544)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705028 sequences (100000028 bp) in 2.041 CPU sec, 2.083 real sec...
[M::mem_process_seqs] Processed 704682 reads in 191.410 CPU sec, 6.158 real sec
[M::mem_process_seqs] Processed 705972 reads in 129.188 CPU sec, 4.140 real sec
sorting block 49, #reads = 1082893 mem = 536878248 peak = 1011273728
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 290020, 20, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 233, 552)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1370)
[M::mem_pestat] mean and std.dev: (338.67, 295.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1779)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 217, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 655)
[M::mem_pestat] mean and std.dev: (242.50, 121.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 824)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (249, 352, 627)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1383)
[M::mem_pestat] mean and std.dev: (353.35, 193.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1761)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 327, 1328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3558)
[M::mem_pestat] mean and std.dev: (550.33, 612.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4673)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705532 sequences (100000040 bp) in 2.767 CPU sec, 3.092 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 288924, 27, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 192, 398)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 900)
[M::mem_pestat] mean and std.dev: (293.67, 229.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1213)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 221, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667)
[M::mem_pestat] mean and std.dev: (247.18, 123.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 839)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 651, 1593)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4249)
[M::mem_pestat] mean and std.dev: (911.40, 1005.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5577)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 272, 414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 912)
[M::mem_pestat] mean and std.dev: (269.49, 140.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1161)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706674 reads in 186.456 CPU sec, 6.017 real sec
[M::process] read 707542 sequences (100000079 bp) in 1.774 CPU sec, 1.792 real sec...
sorting block 50, #reads = 1083907 mem = 536881771 peak = 1011273728
[M::mem_process_seqs] Processed 705028 reads in 125.147 CPU sec, 4.227 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (93, 289361, 12, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 243, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1024)
[M::mem_pestat] mean and std.dev: (266.87, 162.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1308)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 220, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (246.27, 123.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 838)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (280, 547, 577)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1171)
[M::mem_pestat] mean and std.dev: (408.42, 207.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1468)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 249, 638)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1544)
[M::mem_pestat] mean and std.dev: (359.21, 258.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1997)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 51, #reads = 1085445 mem = 536878128 peak = 1011273728
[M::process] read 706560 sequences (100000210 bp) in 2.761 CPU sec, 3.100 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 290161, 29, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 307, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 903)
[M::mem_pestat] mean and std.dev: (255.38, 96.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1137)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 214, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 645)
[M::mem_pestat] mean and std.dev: (240.01, 119.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 811)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 299, 1108)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3058)
[M::mem_pestat] mean and std.dev: (517.04, 592.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4033)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 276, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1049)
[M::mem_pestat] mean and std.dev: (279.46, 197.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1343)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703640 sequences (100000094 bp) in 1.918 CPU sec, 1.922 real sec...
[M::mem_process_seqs] Processed 705532 reads in 194.638 CPU sec, 6.555 real sec
[M::mem_process_seqs] Processed 707542 reads in 127.412 CPU sec, 4.146 real sec
sorting block 52, #reads = 1084497 mem = 536881058 peak = 1011273728
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 289323, 17, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 210, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 929)
[M::mem_pestat] mean and std.dev: (271.46, 164.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1178)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 218, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 659)
[M::mem_pestat] mean and std.dev: (243.98, 122.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 829)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 466, 1363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3671)
[M::mem_pestat] mean and std.dev: (725.62, 737.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4825)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 308, 483)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1075)
[M::mem_pestat] mean and std.dev: (319.02, 198.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1371)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705052 sequences (100000101 bp) in 2.671 CPU sec, 3.100 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 288046, 18, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 220, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 997)
[M::mem_pestat] mean and std.dev: (243.53, 148.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1277)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 226, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (252.46, 127.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 865)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (24, 454, 1147)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3393)
[M::mem_pestat] mean and std.dev: (593.29, 621.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4516)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 284, 413)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 861)
[M::mem_pestat] mean and std.dev: (295.40, 149.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1085)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703328 sequences (100000279 bp) in 1.763 CPU sec, 1.821 real sec...
[M::mem_process_seqs] Processed 706560 reads in 189.667 CPU sec, 6.118 real sec
[M::mem_process_seqs] Processed 703640 reads in 126.880 CPU sec, 4.094 real sec
sorting block 53, #reads = 1083569 mem = 536879719 peak = 1011273728
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 288464, 20, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 300, 702)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1724)
[M::mem_pestat] mean and std.dev: (404.00, 317.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2235)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 223, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 676)
[M::mem_pestat] mean and std.dev: (248.54, 124.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 851)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 625, 822)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2120)
[M::mem_pestat] mean and std.dev: (515.89, 397.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2769)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 309, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 995)
[M::mem_pestat] mean and std.dev: (311.40, 164.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1261)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702512 sequences (100000073 bp) in 2.728 CPU sec, 3.184 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 288060, 23, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 257, 598)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1422)
[M::mem_pestat] mean and std.dev: (310.19, 232.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1834)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 226, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684)
[M::mem_pestat] mean and std.dev: (251.66, 125.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 861)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (441, 1136, 1880)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4758)
[M::mem_pestat] mean and std.dev: (900.00, 629.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6197)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 279, 509)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1163)
[M::mem_pestat] mean and std.dev: (292.72, 193.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1490)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702382 sequences (100000301 bp) in 2.056 CPU sec, 2.060 real sec...
[M::mem_process_seqs] Processed 705052 reads in 195.936 CPU sec, 6.345 real sec
sorting block 54, #reads = 1082498 mem = 536879217 peak = 1011273728
[M::mem_process_seqs] Processed 703328 reads in 128.167 CPU sec, 4.161 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 287902, 20, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 293, 572)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1338)
[M::mem_pestat] mean and std.dev: (333.05, 213.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1721)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 226, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 676)
[M::mem_pestat] mean and std.dev: (250.86, 123.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 850)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 416, 2072)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5896)
[M::mem_pestat] mean and std.dev: (1111.35, 1389.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7808)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 206, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (221.13, 101.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 55, #reads = 1083331 mem = 536878850 peak = 1011273728
[M::process] read 702462 sequences (100000111 bp) in 2.804 CPU sec, 3.107 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 287746, 27, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 283, 746)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1860)
[M::mem_pestat] mean and std.dev: (418.88, 355.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2417)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (252.01, 125.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 491, 3209)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9281)
[M::mem_pestat] mean and std.dev: (1832.19, 2322.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12317)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 298, 734)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1800)
[M::mem_pestat] mean and std.dev: (435.00, 313.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2333)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703232 sequences (100000269 bp) in 1.951 CPU sec, 2.032 real sec...
[M::mem_process_seqs] Processed 702512 reads in 195.899 CPU sec, 6.463 real sec
[M::mem_process_seqs] Processed 702382 reads in 126.410 CPU sec, 4.067 real sec
sorting block 56, #reads = 1080961 mem = 536883044 peak = 1011273728
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 287502, 23, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 290, 493)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1121)
[M::mem_pestat] mean and std.dev: (291.64, 166.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1435)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (252.24, 125.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (93, 418, 735)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2019)
[M::mem_pestat] mean and std.dev: (304.06, 265.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2661)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 378, 710)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1704)
[M::mem_pestat] mean and std.dev: (458.46, 372.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2201)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702032 sequences (100000023 bp) in 2.768 CPU sec, 3.181 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 287822, 20, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 292, 509)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1191)
[M::mem_pestat] mean and std.dev: (322.40, 228.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1532)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 224, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (247.93, 122.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 837)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 525, 714)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1786)
[M::mem_pestat] mean and std.dev: (440.26, 350.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2322)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 274, 429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 963)
[M::mem_pestat] mean and std.dev: (289.63, 159.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1230)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703114 sequences (100000093 bp) in 1.941 CPU sec, 2.047 real sec...
[M::mem_process_seqs] Processed 702462 reads in 200.157 CPU sec, 6.498 real sec
[M::mem_process_seqs] Processed 703232 reads in 129.663 CPU sec, 4.220 real sec
sorting block 57, #reads = 1080314 mem = 536878863 peak = 1011273728
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 287521, 31, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 261, 526)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1268)
[M::mem_pestat] mean and std.dev: (358.91, 300.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1639)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 227, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (252.58, 125.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 855)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (124, 619, 950)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2602)
[M::mem_pestat] mean and std.dev: (549.37, 529.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3428)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 298, 774)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1952)
[M::mem_pestat] mean and std.dev: (370.26, 297.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2541)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703434 sequences (100000123 bp) in 2.806 CPU sec, 3.221 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 287697, 35, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 306, 626)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1496)
[M::mem_pestat] mean and std.dev: (374.39, 284.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1931)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 223, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (248.41, 122.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 837)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 825, 3624)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10424)
[M::mem_pestat] mean and std.dev: (2179.86, 3046.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14368)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 238, 381)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 799)
[M::mem_pestat] mean and std.dev: (262.70, 140.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1008)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 709658 sequences (100000159 bp) in 1.993 CPU sec, 2.014 real sec...
[M::mem_process_seqs] Processed 702032 reads in 196.316 CPU sec, 6.366 real sec
sorting block 58, #reads = 1082277 mem = 536879347 peak = 1011273728
[M::mem_process_seqs] Processed 703114 reads in 128.290 CPU sec, 4.171 real sec
sorting block 59, #reads = 1080112 mem = 536879333 peak = 1011273728
[M::process] read 707900 sequences (100000033 bp) in 2.948 CPU sec, 3.240 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 290748, 18, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 283, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1008)
[M::mem_pestat] mean and std.dev: (311.45, 194.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1279)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 210, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 628)
[M::mem_pestat] mean and std.dev: (235.04, 116.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 789)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (76, 452, 786)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2206)
[M::mem_pestat] mean and std.dev: (538.24, 526.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2916)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 259, 505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1129)
[M::mem_pestat] mean and std.dev: (264.30, 140.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1441)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707090 sequences (100000054 bp) in 1.948 CPU sec, 1.956 real sec...
[M::mem_process_seqs] Processed 709658 reads in 123.496 CPU sec, 3.967 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 287746, 24, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 237, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 819)
[M::mem_pestat] mean and std.dev: (250.90, 161.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1042)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 223, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 672)
[M::mem_pestat] mean and std.dev: (249.23, 124.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 845)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (459, 897, 1982)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5028)
[M::mem_pestat] mean and std.dev: (1183.12, 973.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6551)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 284, 421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 827)
[M::mem_pestat] mean and std.dev: (312.06, 160.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1030)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 290389, 21, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 207, 507)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1219)
[M::mem_pestat] mean and std.dev: (253.53, 224.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1575)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 216, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 654)
[M::mem_pestat] mean and std.dev: (241.39, 120.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 823)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 510, 1469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4061)
[M::mem_pestat] mean and std.dev: (760.48, 629.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5357)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 264, 473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1111)
[M::mem_pestat] mean and std.dev: (336.13, 233.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1430)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706914 sequences (100000076 bp) in 2.143 CPU sec, 2.216 real sec...
[M::mem_process_seqs] Processed 703434 reads in 334.981 CPU sec, 10.908 real sec
sorting block 60, #reads = 1078293 mem = 536880718 peak = 1011273728
[M::mem_process_seqs] Processed 707900 reads in 170.428 CPU sec, 5.491 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 289603, 16, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 238, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 802)
[M::mem_pestat] mean and std.dev: (270.70, 156.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1016)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 217, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 652)
[M::mem_pestat] mean and std.dev: (241.71, 119.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 820)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (324, 711, 2872)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7968)
[M::mem_pestat] mean and std.dev: (1106.20, 1244.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10516)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 332, 582)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1382)
[M::mem_pestat] mean and std.dev: (427.03, 322.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1782)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706048 sequences (100000256 bp) in 2.570 CPU sec, 2.952 real sec...
sorting block 61, #reads = 1078140 mem = 536878400 peak = 1035309056
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 289819, 24, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 284, 396)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 872)
[M::mem_pestat] mean and std.dev: (283.95, 153.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1110)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 217, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 652)
[M::mem_pestat] mean and std.dev: (241.72, 119.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 820)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (417, 814, 2194)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5748)
[M::mem_pestat] mean and std.dev: (1123.58, 897.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7525)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 367, 1160)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3080)
[M::mem_pestat] mean and std.dev: (592.89, 625.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4040)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707446 sequences (100000176 bp) in 1.859 CPU sec, 1.907 real sec...
[M::mem_process_seqs] Processed 707090 reads in 204.892 CPU sec, 6.609 real sec
[M::mem_process_seqs] Processed 706914 reads in 140.624 CPU sec, 4.513 real sec
sorting block 62, #reads = 1079436 mem = 536884475 peak = 1035309056
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 289848, 23, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 239, 606)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1484)
[M::mem_pestat] mean and std.dev: (321.70, 232.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1923)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 219, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 656)
[M::mem_pestat] mean and std.dev: (243.84, 120.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 825)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (466, 568, 1438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3382)
[M::mem_pestat] mean and std.dev: (951.00, 916.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4617)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 352, 632)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1472)
[M::mem_pestat] mean and std.dev: (374.67, 238.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1892)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707016 sequences (100000161 bp) in 2.606 CPU sec, 3.107 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 290443, 14, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 296, 645)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1535)
[M::mem_pestat] mean and std.dev: (446.06, 369.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1980)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 215, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 645)
[M::mem_pestat] mean and std.dev: (240.16, 119.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 811)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (297, 720, 823)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1875)
[M::mem_pestat] mean and std.dev: (574.23, 383.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2401)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 273, 581)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1363)
[M::mem_pestat] mean and std.dev: (399.02, 336.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1754)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703764 sequences (100000089 bp) in 1.918 CPU sec, 1.920 real sec...
[M::mem_process_seqs] Processed 706048 reads in 204.189 CPU sec, 6.611 real sec
[M::mem_process_seqs] Processed 707446 reads in 137.472 CPU sec, 4.498 real sec
sorting block 63, #reads = 1082804 mem = 536880330 peak = 1035309056
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 289943, 23, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 281, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1086)
[M::mem_pestat] mean and std.dev: (344.67, 231.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1395)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 217, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 649)
[M::mem_pestat] mean and std.dev: (241.47, 119.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 816)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 644, 2689)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7671)
[M::mem_pestat] mean and std.dev: (1000.40, 1117.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10162)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 299, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 996)
[M::mem_pestat] mean and std.dev: (375.58, 235.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1316)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705306 sequences (100000177 bp) in 2.724 CPU sec, 3.198 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 288845, 26, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 295, 646)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1602)
[M::mem_pestat] mean and std.dev: (333.48, 281.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2080)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 225, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (251.73, 126.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 865)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (101, 439, 1080)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3038)
[M::mem_pestat] mean and std.dev: (467.79, 430.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4017)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 276, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 745)
[M::mem_pestat] mean and std.dev: (271.83, 140.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 940)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704056 sequences (100000027 bp) in 2.136 CPU sec, 2.153 real sec...
[M::mem_process_seqs] Processed 707016 reads in 207.472 CPU sec, 6.804 real sec
[M::mem_process_seqs] Processed 703764 reads in 135.864 CPU sec, 4.350 real sec
sorting block 64, #reads = 1082765 mem = 536877480 peak = 1035309056
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 288728, 17, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 305, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 673)
[M::mem_pestat] mean and std.dev: (275.15, 112.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 835)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 221, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667)
[M::mem_pestat] mean and std.dev: (246.78, 123.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 839)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (86, 325, 1016)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2876)
[M::mem_pestat] mean and std.dev: (585.44, 759.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3806)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 240, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1009)
[M::mem_pestat] mean and std.dev: (243.84, 120.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1289)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704122 sequences (100000001 bp) in 2.619 CPU sec, 3.040 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 288421, 24, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 390, 816)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2056)
[M::mem_pestat] mean and std.dev: (336.88, 227.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2676)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 223, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (248.80, 124.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 848)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (309, 424, 827)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1863)
[M::mem_pestat] mean and std.dev: (525.18, 385.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2381)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 277, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1027)
[M::mem_pestat] mean and std.dev: (311.66, 187.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1307)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701902 sequences (100000026 bp) in 1.770 CPU sec, 1.812 real sec...
[M::mem_process_seqs] Processed 705306 reads in 199.966 CPU sec, 6.547 real sec
sorting block 65, #reads = 1081890 mem = 536879808 peak = 1035309056
[M::mem_process_seqs] Processed 704056 reads in 130.816 CPU sec, 4.192 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (86, 288371, 24, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 265, 737)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1913)
[M::mem_pestat] mean and std.dev: (426.60, 411.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2501)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 223, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (248.40, 123.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 844)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (270, 926, 1280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3300)
[M::mem_pestat] mean and std.dev: (643.48, 440.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4310)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 281, 481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 993)
[M::mem_pestat] mean and std.dev: (313.47, 154.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1249)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 66, #reads = 1081349 mem = 536881296 peak = 1093107712
[M::process] read 703138 sequences (100000014 bp) in 2.514 CPU sec, 2.988 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 287828, 27, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 273, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 999)
[M::mem_pestat] mean and std.dev: (301.66, 186.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1269)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 229, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (254.39, 127.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (345, 453, 3954)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11172)
[M::mem_pestat] mean and std.dev: (1568.22, 1781.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14781)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 356, 643)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1497)
[M::mem_pestat] mean and std.dev: (412.12, 289.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1924)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703530 sequences (100000138 bp) in 2.092 CPU sec, 2.143 real sec...
[M::mem_process_seqs] Processed 704122 reads in 196.851 CPU sec, 6.393 real sec
[M::mem_process_seqs] Processed 701902 reads in 131.214 CPU sec, 4.218 real sec
sorting block 67, #reads = 1081990 mem = 536876600 peak = 1093107712
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 287451, 35, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (110, 170, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 665)
[M::mem_pestat] mean and std.dev: (192.95, 126.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 850)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 225, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 669)
[M::mem_pestat] mean and std.dev: (249.33, 123.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 841)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 505, 1498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4128)
[M::mem_pestat] mean and std.dev: (634.03, 614.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5443)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 268, 1060)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2824)
[M::mem_pestat] mean and std.dev: (599.66, 580.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3706)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703736 sequences (100000211 bp) in 2.567 CPU sec, 2.907 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 287948, 26, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 273, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 996)
[M::mem_pestat] mean and std.dev: (307.49, 171.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1270)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 223, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (248.59, 123.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 840)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (450, 652, 1189)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2667)
[M::mem_pestat] mean and std.dev: (808.25, 536.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3406)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 362, 576)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1258)
[M::mem_pestat] mean and std.dev: (337.75, 187.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1599)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704658 sequences (100000172 bp) in 1.867 CPU sec, 1.901 real sec...
[M::mem_process_seqs] Processed 703138 reads in 192.963 CPU sec, 6.225 real sec
[M::mem_process_seqs] Processed 703530 reads in 131.558 CPU sec, 4.436 real sec
sorting block 68, #reads = 1081663 mem = 536880013 peak = 1093107712
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 287664, 29, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 384, 474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1066)
[M::mem_pestat] mean and std.dev: (294.21, 150.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1362)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 222, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (248.15, 124.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 840)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 436, 1330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3716)
[M::mem_pestat] mean and std.dev: (695.93, 637.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4909)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 290, 617)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1495)
[M::mem_pestat] mean and std.dev: (413.34, 346.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1934)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706366 sequences (100000224 bp) in 2.793 CPU sec, 3.274 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 287972, 14, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 348, 675)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1675)
[M::mem_pestat] mean and std.dev: (389.97, 284.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2175)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 221, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (246.35, 123.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 831)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 407, 878)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2298)
[M::mem_pestat] mean and std.dev: (510.79, 400.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3008)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 306, 534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1206)
[M::mem_pestat] mean and std.dev: (397.04, 272.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1542)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705494 sequences (100000200 bp) in 1.803 CPU sec, 1.813 real sec...
[M::mem_process_seqs] Processed 703736 reads in 202.258 CPU sec, 6.762 real sec
sorting block 69, #reads = 1082146 mem = 536883222 peak = 1093107712
[M::mem_process_seqs] Processed 704658 reads in 135.255 CPU sec, 4.434 real sec
sorting block 70, #reads = 1079947 mem = 536880074 peak = 1093107712
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 289142, 13, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 274, 474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1084)
[M::mem_pestat] mean and std.dev: (251.60, 135.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1389)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 217, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 650)
[M::mem_pestat] mean and std.dev: (242.55, 120.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 817)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (302, 725, 3305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9311)
[M::mem_pestat] mean and std.dev: (1198.00, 1205.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12314)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 308, 1076)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2802)
[M::mem_pestat] mean and std.dev: (587.77, 643.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3665)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705092 sequences (100000029 bp) in 2.598 CPU sec, 2.804 real sec...
[M::process] read 704066 sequences (100000100 bp) in 1.620 CPU sec, 1.625 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 289325, 41, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 336, 476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1002)
[M::mem_pestat] mean and std.dev: (318.19, 175.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1265)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 220, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (245.81, 122.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 838)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 888, 1175)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3041)
[M::mem_pestat] mean and std.dev: (805.34, 668.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3974)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 275, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 745)
[M::mem_pestat] mean and std.dev: (277.86, 127.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 933)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706366 reads in 209.353 CPU sec, 6.843 real sec
[M::mem_process_seqs] Processed 705494 reads in 129.114 CPU sec, 4.170 real sec
sorting block 71, #reads = 1075872 mem = 536876924 peak = 1093107712
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 289738, 19, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 231, 309)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 607)
[M::mem_pestat] mean and std.dev: (224.94, 92.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 756)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 221, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667)
[M::mem_pestat] mean and std.dev: (246.53, 122.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 839)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (75, 539, 1012)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2886)
[M::mem_pestat] mean and std.dev: (642.58, 686.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3823)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (324, 409, 1396)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3540)
[M::mem_pestat] mean and std.dev: (760.04, 675.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4612)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703178 sequences (100000068 bp) in 2.528 CPU sec, 2.840 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 289641, 19, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 215, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 729)
[M::mem_pestat] mean and std.dev: (233.11, 115.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 920)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 225, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (250.56, 125.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 860)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 441, 2609)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7401)
[M::mem_pestat] mean and std.dev: (1774.84, 2235.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10715)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 274, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1083)
[M::mem_pestat] mean and std.dev: (319.11, 198.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1391)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706886 sequences (100000116 bp) in 2.072 CPU sec, 2.084 real sec...
[M::mem_process_seqs] Processed 705092 reads in 188.207 CPU sec, 6.083 real sec
[M::mem_process_seqs] Processed 704066 reads in 123.625 CPU sec, 3.953 real sec
sorting block 72, #reads = 1086009 mem = 536880549 peak = 1093107712
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 287968, 30, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 226, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 610)
[M::mem_pestat] mean and std.dev: (225.06, 96.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 757)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 228, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (253.00, 125.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 869)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (321, 621, 2941)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8181)
[M::mem_pestat] mean and std.dev: (1642.33, 1752.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10801)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 335, 646)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1632)
[M::mem_pestat] mean and std.dev: (343.02, 257.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2125)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706520 sequences (100000119 bp) in 2.651 CPU sec, 3.028 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 289842, 19, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 316, 536)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1246)
[M::mem_pestat] mean and std.dev: (414.87, 332.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1746)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 218, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653)
[M::mem_pestat] mean and std.dev: (242.13, 119.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 821)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (297, 610, 620)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1266)
[M::mem_pestat] mean and std.dev: (503.12, 233.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1589)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 353, 591)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1379)
[M::mem_pestat] mean and std.dev: (389.05, 303.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1773)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705720 sequences (100000088 bp) in 1.705 CPU sec, 1.735 real sec...
[M::mem_process_seqs] Processed 703178 reads in 191.057 CPU sec, 6.197 real sec
sorting block 73, #reads = 1084518 mem = 536881691 peak = 1093107712
[M::mem_process_seqs] Processed 706886 reads in 125.397 CPU sec, 4.052 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 289997, 25, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 323, 1011)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2553)
[M::mem_pestat] mean and std.dev: (452.36, 379.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3324)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 217, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 650)
[M::mem_pestat] mean and std.dev: (242.08, 119.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 817)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (600, 816, 2114)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5142)
[M::mem_pestat] mean and std.dev: (1276.80, 1234.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6656)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (140, 225, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1097)
[M::mem_pestat] mean and std.dev: (281.33, 233.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1416)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 74, #reads = 1084709 mem = 536879939 peak = 1093107712
[M::process] read 705506 sequences (100000086 bp) in 3.200 CPU sec, 3.413 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 289445, 24, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 362, 724)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1844)
[M::mem_pestat] mean and std.dev: (464.29, 382.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2404)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 220, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 660)
[M::mem_pestat] mean and std.dev: (244.44, 120.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 830)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (439, 935, 1851)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4675)
[M::mem_pestat] mean and std.dev: (872.32, 682.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6087)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 302, 394)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 746)
[M::mem_pestat] mean and std.dev: (281.85, 111.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 922)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706520 reads in 192.984 CPU sec, 6.280 real sec
[M::process] read 702988 sequences (100000106 bp) in 1.759 CPU sec, 1.835 real sec...
[M::mem_process_seqs] Processed 705720 reads in 125.561 CPU sec, 4.247 real sec
sorting block 75, #reads = 1084141 mem = 536886064 peak = 1093107712
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 289164, 10, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 168, 308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 652)
[M::mem_pestat] mean and std.dev: (196.32, 105.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 824)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 220, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 663)
[M::mem_pestat] mean and std.dev: (245.64, 122.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (377, 694, 1401)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3449)
[M::mem_pestat] mean and std.dev: (790.67, 642.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4473)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 396, 654)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1540)
[M::mem_pestat] mean and std.dev: (412.81, 265.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1983)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705302 sequences (100000102 bp) in 2.812 CPU sec, 3.156 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 288460, 6, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 212, 405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 913)
[M::mem_pestat] mean and std.dev: (229.60, 164.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1167)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (252.94, 126.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 284, 655)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1563)
[M::mem_pestat] mean and std.dev: (313.40, 213.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2017)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 705390 sequences (100000286 bp) in 1.720 CPU sec, 1.848 real sec...
[M::mem_process_seqs] Processed 705506 reads in 190.250 CPU sec, 6.381 real sec
[M::mem_process_seqs] Processed 702988 reads in 123.222 CPU sec, 4.052 real sec
sorting block 76, #reads = 1085283 mem = 536879208 peak = 1093107712
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 288979, 20, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 272, 704)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1720)
[M::mem_pestat] mean and std.dev: (437.65, 405.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2228)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 221, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (245.58, 121.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 838)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (291, 538, 936)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2226)
[M::mem_pestat] mean and std.dev: (675.79, 617.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3147)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 407, 510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1154)
[M::mem_pestat] mean and std.dev: (374.48, 217.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1476)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704458 sequences (100000278 bp) in 2.839 CPU sec, 3.301 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 289263, 20, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 322, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1021)
[M::mem_pestat] mean and std.dev: (328.83, 196.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1304)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 221, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 663)
[M::mem_pestat] mean and std.dev: (245.32, 121.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (504, 755, 888)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1656)
[M::mem_pestat] mean and std.dev: (565.94, 350.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2040)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 275, 555)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1303)
[M::mem_pestat] mean and std.dev: (362.89, 290.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1677)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705302 reads in 188.398 CPU sec, 6.113 real sec
[M::process] read 704590 sequences (100000200 bp) in 2.024 CPU sec, 2.083 real sec...
sorting block 77, #reads = 1082931 mem = 536881385 peak = 1093107712
[M::mem_process_seqs] Processed 705390 reads in 125.278 CPU sec, 4.219 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 288262, 20, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 282, 610)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1428)
[M::mem_pestat] mean and std.dev: (393.68, 262.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1837)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 222, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 670)
[M::mem_pestat] mean and std.dev: (247.56, 123.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 843)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (447, 875, 1222)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2772)
[M::mem_pestat] mean and std.dev: (789.41, 537.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3547)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 417, 859)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2153)
[M::mem_pestat] mean and std.dev: (500.51, 394.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2800)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 78, #reads = 1083078 mem = 536878256 peak = 1093107712
[M::process] read 705062 sequences (100000246 bp) in 2.926 CPU sec, 3.334 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 288325, 23, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 263, 827)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2117)
[M::mem_pestat] mean and std.dev: (458.80, 470.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2762)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 222, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667)
[M::mem_pestat] mean and std.dev: (247.45, 123.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 839)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (302, 491, 720)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1556)
[M::mem_pestat] mean and std.dev: (476.62, 284.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1974)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 318, 578)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1270)
[M::mem_pestat] mean and std.dev: (384.00, 263.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1616)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704718 sequences (100000040 bp) in 1.926 CPU sec, 2.026 real sec...
[M::mem_process_seqs] Processed 704458 reads in 200.546 CPU sec, 6.745 real sec
[M::mem_process_seqs] Processed 704590 reads in 129.699 CPU sec, 4.225 real sec
sorting block 79, #reads = 1082587 mem = 536879217 peak = 1093107712
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 288589, 18, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 261, 604)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1452)
[M::mem_pestat] mean and std.dev: (327.05, 233.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1876)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 220, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (245.97, 123.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 838)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (322, 860, 1701)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4459)
[M::mem_pestat] mean and std.dev: (1124.11, 939.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5838)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 237, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1004)
[M::mem_pestat] mean and std.dev: (293.26, 179.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1280)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705420 sequences (100000214 bp) in 2.810 CPU sec, 3.142 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 288961, 30, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 349, 970)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2562)
[M::mem_pestat] mean and std.dev: (532.81, 556.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3358)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 221, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (246.46, 123.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 835)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (86, 648, 2064)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6020)
[M::mem_pestat] mean and std.dev: (990.23, 1358.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7998)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 235, 407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 863)
[M::mem_pestat] mean and std.dev: (311.00, 193.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1091)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706418 sequences (100000035 bp) in 2.122 CPU sec, 2.269 real sec...
[M::mem_process_seqs] Processed 705062 reads in 203.288 CPU sec, 6.619 real sec
[M::mem_process_seqs] Processed 704718 reads in 131.501 CPU sec, 4.253 real sec
sorting block 80, #reads = 1081843 mem = 536877342 peak = 1093107712
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 288219, 24, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 253, 434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 938)
[M::mem_pestat] mean and std.dev: (268.94, 134.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1190)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 219, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 654)
[M::mem_pestat] mean and std.dev: (243.67, 121.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 822)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (439, 658, 1585)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3877)
[M::mem_pestat] mean and std.dev: (860.30, 598.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5023)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 341, 611)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1405)
[M::mem_pestat] mean and std.dev: (351.59, 192.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1802)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 709104 sequences (100000136 bp) in 2.799 CPU sec, 3.367 real sec...
[M::process] read 709176 sequences (100000154 bp) in 1.886 CPU sec, 1.893 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 288956, 18, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 338, 693)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1675)
[M::mem_pestat] mean and std.dev: (348.81, 228.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2166)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 216, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 643)
[M::mem_pestat] mean and std.dev: (240.73, 119.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 808)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 705, 1189)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3125)
[M::mem_pestat] mean and std.dev: (627.19, 543.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4093)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 268, 688)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1692)
[M::mem_pestat] mean and std.dev: (399.45, 354.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2194)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705420 reads in 214.852 CPU sec, 6.934 real sec
[M::mem_process_seqs] Processed 706418 reads in 149.644 CPU sec, 4.865 real sec
sorting block 81, #reads = 1080680 mem = 536880236 peak = 1093107712
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 289722, 19, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 260, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1118)
[M::mem_pestat] mean and std.dev: (287.97, 163.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1441)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 212, 311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 641)
[M::mem_pestat] mean and std.dev: (238.01, 118.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 806)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 930, 2462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6968)
[M::mem_pestat] mean and std.dev: (748.60, 753.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9221)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 233, 429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 895)
[M::mem_pestat] mean and std.dev: (273.26, 132.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1128)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 82, #reads = 1075983 mem = 536884822 peak = 1093107712
[M::process] read 707292 sequences (100000230 bp) in 2.499 CPU sec, 2.761 real sec...
[M::process] read 708024 sequences (100000057 bp) in 2.031 CPU sec, 2.084 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 290494, 26, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 304, 565)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1323)
[M::mem_pestat] mean and std.dev: (325.67, 188.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1702)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 213, 311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 641)
[M::mem_pestat] mean and std.dev: (238.22, 118.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 806)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (327, 570, 1465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3741)
[M::mem_pestat] mean and std.dev: (912.04, 696.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4879)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 296, 464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1024)
[M::mem_pestat] mean and std.dev: (296.52, 155.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1304)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 709104 reads in 221.871 CPU sec, 7.212 real sec
[M::mem_process_seqs] Processed 709176 reads in 149.914 CPU sec, 4.820 real sec
sorting block 83, #reads = 1076843 mem = 536879079 peak = 1093107712
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 289531, 17, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 214, 830)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2182)
[M::mem_pestat] mean and std.dev: (428.78, 474.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2858)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 217, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 655)
[M::mem_pestat] mean and std.dev: (242.18, 120.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 824)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (292, 439, 1328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3400)
[M::mem_pestat] mean and std.dev: (731.75, 682.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4436)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 429, 1270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3336)
[M::mem_pestat] mean and std.dev: (688.10, 713.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4369)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 709178 sequences (100000125 bp) in 2.623 CPU sec, 3.005 real sec...
[M::process] read 709370 sequences (100000092 bp) in 2.003 CPU sec, 2.005 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 290139, 20, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 282, 501)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1195)
[M::mem_pestat] mean and std.dev: (288.12, 207.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1542)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 216, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 657)
[M::mem_pestat] mean and std.dev: (242.19, 121.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 827)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (895, 1316, 1934)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4012)
[M::mem_pestat] mean and std.dev: (1178.33, 692.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5051)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 331, 1186)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3108)
[M::mem_pestat] mean and std.dev: (611.05, 574.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4069)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707292 reads in 203.622 CPU sec, 6.544 real sec
[M::mem_process_seqs] Processed 708024 reads in 137.525 CPU sec, 4.403 real sec
sorting block 84, #reads = 1078067 mem = 536879464 peak = 1093107712
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 290463, 16, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 234, 426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 946)
[M::mem_pestat] mean and std.dev: (253.81, 148.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1206)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 212, 309)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 635)
[M::mem_pestat] mean and std.dev: (237.39, 118.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 798)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (327, 648, 1532)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3942)
[M::mem_pestat] mean and std.dev: (767.60, 562.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5147)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 284, 698)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1646)
[M::mem_pestat] mean and std.dev: (362.10, 270.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2120)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707474 sequences (100000259 bp) in 2.773 CPU sec, 3.189 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 290400, 23, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 202, 509)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1203)
[M::mem_pestat] mean and std.dev: (295.83, 206.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1550)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 211, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 628)
[M::mem_pestat] mean and std.dev: (235.33, 115.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 789)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 253, 634)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1522)
[M::mem_pestat] mean and std.dev: (327.85, 221.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1966)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 281, 384)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 740)
[M::mem_pestat] mean and std.dev: (282.29, 143.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 918)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704508 sequences (100000004 bp) in 2.030 CPU sec, 2.040 real sec...
[M::mem_process_seqs] Processed 709178 reads in 207.583 CPU sec, 6.738 real sec
[M::mem_process_seqs] Processed 709370 reads in 137.863 CPU sec, 4.443 real sec
sorting block 85, #reads = 1082315 mem = 536878396 peak = 1093107712
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 289931, 27, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 283, 831)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2173)
[M::mem_pestat] mean and std.dev: (428.16, 403.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2844)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 215, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 640)
[M::mem_pestat] mean and std.dev: (239.34, 117.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 804)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (121, 315, 1202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3364)
[M::mem_pestat] mean and std.dev: (753.04, 869.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4445)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 284, 488)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1126)
[M::mem_pestat] mean and std.dev: (306.36, 186.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1445)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706530 sequences (100000115 bp) in 2.931 CPU sec, 3.244 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 288594, 20, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 293, 523)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1131)
[M::mem_pestat] mean and std.dev: (375.97, 289.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1535)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 223, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (247.90, 122.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 844)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1173, 1175, 3443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7983)
[M::mem_pestat] mean and std.dev: (1793.70, 1387.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10253)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 343, 1039)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2713)
[M::mem_pestat] mean and std.dev: (534.79, 529.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3550)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705776 sequences (100000108 bp) in 2.000 CPU sec, 2.018 real sec...
[M::mem_process_seqs] Processed 707474 reads in 201.957 CPU sec, 6.511 real sec
sorting block 86, #reads = 1082396 mem = 536877535 peak = 1093107712
[M::mem_process_seqs] Processed 704508 reads in 130.549 CPU sec, 4.196 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 289820, 17, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 295, 545)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1235)
[M::mem_pestat] mean and std.dev: (334.52, 226.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1580)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 218, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653)
[M::mem_pestat] mean and std.dev: (242.81, 119.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 821)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (360, 943, 1495)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3765)
[M::mem_pestat] mean and std.dev: (862.69, 607.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4900)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 306, 505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1127)
[M::mem_pestat] mean and std.dev: (322.19, 171.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1438)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 87, #reads = 1081615 mem = 536879857 peak = 1093107712
[M::process] read 705728 sequences (100000118 bp) in 2.738 CPU sec, 3.081 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 289376, 24, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 232, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 630)
[M::mem_pestat] mean and std.dev: (232.53, 76.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 779)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 220, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 657)
[M::mem_pestat] mean and std.dev: (244.20, 120.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 826)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 520, 1960)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5572)
[M::mem_pestat] mean and std.dev: (683.86, 896.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7378)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 296, 605)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1447)
[M::mem_pestat] mean and std.dev: (392.50, 334.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1868)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705302 sequences (100000241 bp) in 2.037 CPU sec, 2.055 real sec...
[M::mem_process_seqs] Processed 706530 reads in 198.241 CPU sec, 6.491 real sec
[M::mem_process_seqs] Processed 705776 reads in 128.833 CPU sec, 4.218 real sec
sorting block 88, #reads = 1082522 mem = 536880952 peak = 1093107712
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 289387, 28, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 451, 991)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2625)
[M::mem_pestat] mean and std.dev: (487.02, 512.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3442)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 219, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 654)
[M::mem_pestat] mean and std.dev: (243.64, 120.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 822)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (422, 886, 2325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6131)
[M::mem_pestat] mean and std.dev: (1175.33, 1046.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8034)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 261, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 979)
[M::mem_pestat] mean and std.dev: (283.98, 148.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1247)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704928 sequences (100000151 bp) in 2.803 CPU sec, 3.091 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 288794, 17, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 303, 619)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1533)
[M::mem_pestat] mean and std.dev: (333.21, 246.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1990)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 220, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 660)
[M::mem_pestat] mean and std.dev: (245.18, 121.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 830)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (280, 609, 3162)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8926)
[M::mem_pestat] mean and std.dev: (1444.29, 1765.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11808)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 323, 1259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3413)
[M::mem_pestat] mean and std.dev: (596.09, 801.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4490)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704842 sequences (100000056 bp) in 1.810 CPU sec, 1.878 real sec...
[M::mem_process_seqs] Processed 705728 reads in 197.157 CPU sec, 6.428 real sec
[M::mem_process_seqs] Processed 705302 reads in 128.612 CPU sec, 4.185 real sec
sorting block 89, #reads = 1083894 mem = 536881130 peak = 1093107712
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 288879, 17, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 311, 604)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1402)
[M::mem_pestat] mean and std.dev: (352.75, 223.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1801)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 221, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (245.66, 121.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 831)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 475, 1713)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4655)
[M::mem_pestat] mean and std.dev: (672.27, 704.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6126)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 388, 583)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1323)
[M::mem_pestat] mean and std.dev: (384.30, 213.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1693)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704884 sequences (100000037 bp) in 2.743 CPU sec, 3.044 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 288485, 22, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 312, 531)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1133)
[M::mem_pestat] mean and std.dev: (331.91, 200.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1434)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 221, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 658)
[M::mem_pestat] mean and std.dev: (245.21, 121.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 827)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 1453, 7700)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 22646)
[M::mem_pestat] mean and std.dev: (3389.59, 3591.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 30119)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 315, 519)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1197)
[M::mem_pestat] mean and std.dev: (310.52, 173.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1536)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704546 sequences (100000165 bp) in 2.056 CPU sec, 2.076 real sec...
[M::mem_process_seqs] Processed 704928 reads in 198.727 CPU sec, 6.495 real sec
sorting block 90, #reads = 1082873 mem = 536882250 peak = 1093107712
[M::mem_process_seqs] Processed 704842 reads in 131.204 CPU sec, 4.208 real sec
[M::process] read 231912 sequences (32769798 bp) in 0.950 CPU sec, 1.015 real sec...
sorting block 91, #reads = 1082179 mem = 536882073 peak = 1093107712
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 288619, 21, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 279, 844)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2122)
[M::mem_pestat] mean and std.dev: (455.31, 363.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2761)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 221, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 658)
[M::mem_pestat] mean and std.dev: (245.46, 121.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 827)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 671, 1362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3604)
[M::mem_pestat] mean and std.dev: (944.81, 878.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4725)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 306, 724)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1724)
[M::mem_pestat] mean and std.dev: (415.68, 289.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2224)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704884 reads in 107.183 CPU sec, 3.618 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (79, 288611, 23, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 269, 419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 907)
[M::mem_pestat] mean and std.dev: (267.71, 134.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1151)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 221, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (246.22, 122.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 831)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 689, 3092)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9004)
[M::mem_pestat] mean and std.dev: (2283.48, 2963.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14139)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 221, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 636)
[M::mem_pestat] mean and std.dev: (232.57, 102.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 791)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (15, 94835, 3, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 318, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (50, 520)
[M::mem_pestat] mean and std.dev: (251.50, 80.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 614)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 215, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 642)
[M::mem_pestat] mean and std.dev: (239.65, 119.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 807)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 300, 1637)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4571)
[M::mem_pestat] mean and std.dev: (724.13, 857.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6038)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704546 reads in 160.260 CPU sec, 5.344 real sec
[M::mem_process_seqs] Processed 231912 reads in 57.806 CPU sec, 1.879 real sec
sorting block 92, #reads = 1083567 mem = 536880301 peak = 1093107712
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 100839618
overall: 69931999232 mem 16279.005 user 368.391 sys 554.381 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1136_4ZB-T1-TDNA-1_A23MHWWLT4_1.L008\tPU:L008\tSM:1136_4ZB-T1-TDNA-1_A23MHWWLT4_1\tLB:1136_4ZB-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1136_4ZB-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1136_4ZB-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 554.420 sec; CPU: 16647.400 sec
sorting block 93, #reads = 834264 mem = 414129469 peak = 1093107712
uniq header count 1
merging 94 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31 max 192
algo: util-sort
license: sentieon:util=1
output file size: 5519983071
output reads: 101558844
bam_mem_sort: 94 calls 59.901 user 2.012 sys 64.512 real
bam_write: 94 calls 58.520 user 4.094 sys 123.714 real
execute: 1 calls 30.649 user 2.190 sys 593.873 real
merge_files: 1 calls 30.626 user 2.168 sys 38.930 real
parse_chunk: 1501 calls 69.268 user 17.263 sys 112.626 real
read_chunk: 4060 calls 36.296 user 18.848 sys 506.184 real
sort_block: 1 calls 23.287 user 18.220 sys 485.365 real
write_chunk: 2557 calls 30.045 user 1.894 sys 37.573 real
overall: 3048497152 mem 1413.087 user 61.004 sys 593.895 real
ls: cannot access '*.cram': No such file or directory