File Info

Filename
.command.log
Full Path
s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/23/852fa4b1a2b6bca5aed9e19ece9e8e/.command.log
Size
336.5 KB
Attempt
  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/23/852fa4b1a2b6bca5aed9e19ece9e8e/.command.sh
  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta.fai
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/9e/dda19cee142c359a755e61024499f8/1136_4XR-T1-TDNA-1_A23MHWWLT4_1/1136_4XR-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz
  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/BWAIndex
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/23/852fa4b1a2b6bca5aed9e19ece9e8e/.command.run
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/9e/dda19cee142c359a755e61024499f8/1136_4XR-T1-TDNA-1_A23MHWWLT4_1/1136_4XR-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
==> STAGING COMPLETE (7 inputs)

This software is licensed to bgold@natera.com by Sentieon Inc.
cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1136_4XR-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 2601.078 CPU sec, 101.490 real sec
[M::process] read 684956 sequences (100000070 bp) in 1.406 CPU sec, 1.408 real sec...
[M::process] read 684282 sequences (100000161 bp) in 1.819 CPU sec, 1.822 real sec...
[M::process] read 683648 sequences (100000077 bp) in 1.314 CPU sec, 1.315 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 282117, 5, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 272, 713)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1813)
[M::mem_pestat] mean and std.dev: (276.78, 203.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2363)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 297, 417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 859)
[M::mem_pestat] mean and std.dev: (316.59, 151.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1080)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 267, 820)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2142)
[M::mem_pestat] mean and std.dev: (446.20, 492.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2803)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683410 sequences (100000165 bp) in 1.324 CPU sec, 1.346 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 281226, 19, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 298, 761)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1923)
[M::mem_pestat] mean and std.dev: (512.02, 524.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2610)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 300, 419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 863)
[M::mem_pestat] mean and std.dev: (318.38, 151.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1085)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (436, 829, 952)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1984)
[M::mem_pestat] mean and std.dev: (776.53, 389.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2500)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 332, 721)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1825)
[M::mem_pestat] mean and std.dev: (392.24, 346.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2377)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 281348, 9, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 237, 279)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (51, 431)
[M::mem_pestat] mean and std.dev: (211.68, 56.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 507)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 303, 421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 863)
[M::mem_pestat] mean and std.dev: (320.51, 151.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1084)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 181, 391)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 859)
[M::mem_pestat] mean and std.dev: (209.57, 116.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1093)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684956 reads in 305.193 CPU sec, 9.834 real sec
[M::mem_process_seqs] Processed 684282 reads in 198.540 CPU sec, 6.497 real sec
[M::mem_process_seqs] Processed 683648 reads in 217.673 CPU sec, 7.123 real sec
sorting block 0, #reads = 1078587 mem = 536877435 peak = 579616768
[M::process] read 682626 sequences (100000263 bp) in 2.559 CPU sec, 2.709 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 282016, 12, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 274, 1233)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3375)
[M::mem_pestat] mean and std.dev: (658.39, 669.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4446)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 305, 424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 868)
[M::mem_pestat] mean and std.dev: (323.09, 152.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1090)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (88, 568, 2501)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7327)
[M::mem_pestat] mean and std.dev: (867.08, 1049.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9740)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 292, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 732)
[M::mem_pestat] mean and std.dev: (265.78, 104.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 915)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682362 sequences (100000159 bp) in 1.563 CPU sec, 1.588 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 280934, 17, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 289, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (247.61, 86.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 872)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 308, 427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 875)
[M::mem_pestat] mean and std.dev: (325.32, 152.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1099)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 624, 2664)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7508)
[M::mem_pestat] mean and std.dev: (1090.00, 1206.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9930)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 264, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 928)
[M::mem_pestat] mean and std.dev: (302.74, 161.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1169)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682436 sequences (100000249 bp) in 1.230 CPU sec, 1.226 real sec...
[M::mem_process_seqs] Processed 683410 reads in 163.059 CPU sec, 5.182 real sec
sorting block 1, #reads = 1078283 mem = 536880957 peak = 783597568
[M::mem_process_seqs] Processed 682626 reads in 101.580 CPU sec, 3.213 real sec
sorting block 2, #reads = 1076677 mem = 536879250 peak = 883900416
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281192, 5, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 307, 522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1250)
[M::mem_pestat] mean and std.dev: (298.08, 179.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1614)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 308, 427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 873)
[M::mem_pestat] mean and std.dev: (325.16, 151.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1096)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 252, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1029)
[M::mem_pestat] mean and std.dev: (274.15, 130.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1313)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681680 sequences (100000194 bp) in 2.264 CPU sec, 2.370 real sec...
[M::process] read 681316 sequences (100000030 bp) in 1.790 CPU sec, 1.790 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 281276, 6, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 243, 1069)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2845)
[M::mem_pestat] mean and std.dev: (559.64, 605.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3733)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 311, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 880)
[M::mem_pestat] mean and std.dev: (327.79, 153.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1105)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 437, 1884)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5254)
[M::mem_pestat] mean and std.dev: (883.64, 829.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6939)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682362 reads in 159.206 CPU sec, 5.044 real sec
[M::mem_process_seqs] Processed 682436 reads in 100.675 CPU sec, 3.203 real sec
sorting block 3, #reads = 1076219 mem = 536879595 peak = 883900416
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 280439, 17, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 233, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 657)
[M::mem_pestat] mean and std.dev: (227.14, 81.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 818)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 314, 434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 888)
[M::mem_pestat] mean and std.dev: (330.41, 154.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1115)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (331, 624, 1949)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5185)
[M::mem_pestat] mean and std.dev: (1169.88, 847.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6803)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 324, 808)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2030)
[M::mem_pestat] mean and std.dev: (380.17, 251.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2641)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681478 sequences (100000111 bp) in 2.343 CPU sec, 2.453 real sec...
[M::process] read 681474 sequences (100000055 bp) in 1.400 CPU sec, 1.403 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 280692, 2, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (126, 179, 421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1011)
[M::mem_pestat] mean and std.dev: (205.86, 123.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1306)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 318, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 891)
[M::mem_pestat] mean and std.dev: (333.42, 155.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1118)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 326, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1024)
[M::mem_pestat] mean and std.dev: (292.87, 148.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1313)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681680 reads in 167.751 CPU sec, 5.337 real sec
[M::mem_process_seqs] Processed 681316 reads in 108.707 CPU sec, 3.463 real sec
sorting block 4, #reads = 1075458 mem = 536881373 peak = 883900416
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 280700, 20, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 202, 484)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1120)
[M::mem_pestat] mean and std.dev: (267.52, 148.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1438)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 316, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 890)
[M::mem_pestat] mean and std.dev: (332.33, 154.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1117)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (80, 408, 1740)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5060)
[M::mem_pestat] mean and std.dev: (857.15, 926.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6720)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 248, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 718)
[M::mem_pestat] mean and std.dev: (290.38, 145.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 901)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681554 sequences (100000291 bp) in 2.627 CPU sec, 2.773 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 280605, 10, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 412, 515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1133)
[M::mem_pestat] mean and std.dev: (345.72, 171.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1442)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 681582 sequences (100000165 bp) in 1.868 CPU sec, 1.876 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (209, 315, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 887)
[M::mem_pestat] mean and std.dev: (331.12, 153.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1113)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (622, 1627, 9355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 26821)
[M::mem_pestat] mean and std.dev: (3496.40, 3874.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 35554)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 348, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 838)
[M::mem_pestat] mean and std.dev: (296.06, 113.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1037)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681478 reads in 179.548 CPU sec, 5.704 real sec
sorting block 5, #reads = 1075073 mem = 536880249 peak = 883900416
[M::mem_process_seqs] Processed 681474 reads in 117.785 CPU sec, 3.759 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 280701, 7, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 269, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 669)
[M::mem_pestat] mean and std.dev: (261.84, 111.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 846)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 315, 434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 884)
[M::mem_pestat] mean and std.dev: (331.00, 153.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1109)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 229, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 531)
[M::mem_pestat] mean and std.dev: (250.44, 115.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 711)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 6, #reads = 1076478 mem = 536877931 peak = 883900416
[M::process] read 681812 sequences (100000257 bp) in 3.007 CPU sec, 3.265 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281089, 9, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (130, 158, 486)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1198)
[M::mem_pestat] mean and std.dev: (284.72, 229.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1554)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 316, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 893)
[M::mem_pestat] mean and std.dev: (332.38, 155.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1121)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 312, 487)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1069)
[M::mem_pestat] mean and std.dev: (287.16, 134.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1360)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681156 sequences (100000028 bp) in 1.880 CPU sec, 1.876 real sec...
[M::mem_process_seqs] Processed 681554 reads in 179.186 CPU sec, 5.675 real sec
[M::mem_process_seqs] Processed 681582 reads in 115.857 CPU sec, 3.667 real sec
sorting block 7, #reads = 1075969 mem = 536880292 peak = 883900416
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 280654, 6, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 215, 392)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 858)
[M::mem_pestat] mean and std.dev: (295.44, 209.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1134)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 312, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 884)
[M::mem_pestat] mean and std.dev: (329.44, 154.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1110)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 363, 677)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1653)
[M::mem_pestat] mean and std.dev: (446.28, 301.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2141)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680880 sequences (100000087 bp) in 2.774 CPU sec, 2.974 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 280634, 10, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 366, 424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1006)
[M::mem_pestat] mean and std.dev: (297.64, 154.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1297)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 316, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 885)
[M::mem_pestat] mean and std.dev: (332.20, 154.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1110)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (491, 753, 753)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1277)
[M::mem_pestat] mean and std.dev: (604.00, 287.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1753)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 233, 414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 928)
[M::mem_pestat] mean and std.dev: (264.16, 172.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1185)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680904 sequences (100000018 bp) in 1.750 CPU sec, 1.750 real sec...
[M::mem_process_seqs] Processed 681812 reads in 179.317 CPU sec, 5.694 real sec
[M::mem_process_seqs] Processed 681156 reads in 117.544 CPU sec, 3.725 real sec
sorting block 8, #reads = 1075196 mem = 536878615 peak = 883900416
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 280921, 2, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 289, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 911)
[M::mem_pestat] mean and std.dev: (327.05, 187.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1151)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 318, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 892)
[M::mem_pestat] mean and std.dev: (334.23, 155.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1119)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (259, 392, 662)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1468)
[M::mem_pestat] mean and std.dev: (380.95, 178.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1871)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680850 sequences (100000047 bp) in 3.109 CPU sec, 3.273 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 279899, 2, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 432, 539)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1209)
[M::mem_pestat] mean and std.dev: (356.00, 229.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1544)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 314, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 876)
[M::mem_pestat] mean and std.dev: (330.14, 151.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1098)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 330, 665)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1567)
[M::mem_pestat] mean and std.dev: (440.73, 287.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2018)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681166 sequences (100000119 bp) in 2.169 CPU sec, 2.164 real sec...
[M::mem_process_seqs] Processed 680880 reads in 182.577 CPU sec, 5.781 real sec
[M::mem_process_seqs] Processed 680904 reads in 118.288 CPU sec, 3.734 real sec
sorting block 9, #reads = 1074653 mem = 536879900 peak = 883900416
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 280573, 6, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 304, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 827)
[M::mem_pestat] mean and std.dev: (298.09, 156.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1036)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 314, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 876)
[M::mem_pestat] mean and std.dev: (330.40, 152.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1098)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 330, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 879)
[M::mem_pestat] mean and std.dev: (300.38, 117.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1096)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680976 sequences (100000252 bp) in 2.815 CPU sec, 2.998 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 280131, 19, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 245, 1976)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5564)
[M::mem_pestat] mean and std.dev: (922.06, 1200.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7358)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 313, 428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 866)
[M::mem_pestat] mean and std.dev: (328.29, 150.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1085)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (116, 577, 4443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13097)
[M::mem_pestat] mean and std.dev: (1732.21, 2103.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17424)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 286, 601)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1421)
[M::mem_pestat] mean and std.dev: (381.02, 302.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1831)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680662 sequences (100000109 bp) in 1.965 CPU sec, 1.970 real sec...
[M::mem_process_seqs] Processed 680850 reads in 184.823 CPU sec, 5.872 real sec
sorting block 10, #reads = 1075598 mem = 536881203 peak = 883900416
[M::mem_process_seqs] Processed 681166 reads in 120.195 CPU sec, 3.800 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 280493, 7, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 315, 596)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1328)
[M::mem_pestat] mean and std.dev: (402.03, 294.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1694)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 312, 429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 869)
[M::mem_pestat] mean and std.dev: (328.50, 151.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1089)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 339, 434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 964)
[M::mem_pestat] mean and std.dev: (291.56, 141.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1229)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 11, #reads = 1074974 mem = 536879663 peak = 883900416
[M::process] read 681540 sequences (100000015 bp) in 2.962 CPU sec, 3.127 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 280312, 22, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 264, 382)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 774)
[M::mem_pestat] mean and std.dev: (248.38, 114.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 970)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 316, 433)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 877)
[M::mem_pestat] mean and std.dev: (331.63, 152.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1099)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1644, 2374, 7889)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 20379)
[M::mem_pestat] mean and std.dev: (3510.23, 2749.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 26624)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 220, 535)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1249)
[M::mem_pestat] mean and std.dev: (319.69, 260.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1606)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681384 sequences (100000211 bp) in 2.060 CPU sec, 2.060 real sec...
[M::mem_process_seqs] Processed 680976 reads in 183.247 CPU sec, 5.814 real sec
[M::mem_process_seqs] Processed 680662 reads in 115.011 CPU sec, 3.637 real sec
sorting block 12, #reads = 1074160 mem = 536878205 peak = 883900416
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 280262, 8, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 273, 376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 804)
[M::mem_pestat] mean and std.dev: (254.93, 117.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1018)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 310, 428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 868)
[M::mem_pestat] mean and std.dev: (326.88, 151.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1088)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 352, 640)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1482)
[M::mem_pestat] mean and std.dev: (368.35, 219.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1903)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680984 sequences (100000237 bp) in 2.683 CPU sec, 2.890 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 280629, 7, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (281, 328, 553)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1097)
[M::mem_pestat] mean and std.dev: (350.76, 144.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1369)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 311, 429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 871)
[M::mem_pestat] mean and std.dev: (328.26, 152.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1092)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 258, 638)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1482)
[M::mem_pestat] mean and std.dev: (277.70, 201.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1904)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681290 sequences (100000166 bp) in 1.459 CPU sec, 1.454 real sec...
[M::mem_process_seqs] Processed 681540 reads in 160.499 CPU sec, 5.107 real sec
[M::mem_process_seqs] Processed 681384 reads in 103.616 CPU sec, 3.282 real sec
sorting block 13, #reads = 1074816 mem = 536879980 peak = 883900416
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 281015, 6, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 210, 563)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1353)
[M::mem_pestat] mean and std.dev: (340.96, 304.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1748)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 314, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 878)
[M::mem_pestat] mean and std.dev: (329.94, 152.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1101)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 247, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 652)
[M::mem_pestat] mean and std.dev: (264.29, 116.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 808)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681262 sequences (100000033 bp) in 3.005 CPU sec, 3.179 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 280403, 5, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 228, 281)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 545)
[M::mem_pestat] mean and std.dev: (205.93, 76.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 677)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 312, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 874)
[M::mem_pestat] mean and std.dev: (329.02, 152.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1096)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 572, 914)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2252)
[M::mem_pestat] mean and std.dev: (574.36, 472.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2921)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681078 sequences (100000224 bp) in 1.610 CPU sec, 1.603 real sec...
[M::mem_process_seqs] Processed 680984 reads in 164.278 CPU sec, 5.205 real sec
[M::mem_process_seqs] Processed 681290 reads in 105.621 CPU sec, 3.346 real sec
sorting block 14, #reads = 1075140 mem = 536884823 peak = 883900416
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 281039, 16, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 364, 1359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3729)
[M::mem_pestat] mean and std.dev: (576.04, 633.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4914)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 312, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 878)
[M::mem_pestat] mean and std.dev: (329.94, 153.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1101)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (972, 1598, 1661)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3039)
[M::mem_pestat] mean and std.dev: (1180.50, 586.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3728)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 261, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 768)
[M::mem_pestat] mean and std.dev: (242.12, 128.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 968)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680626 sequences (100000241 bp) in 2.622 CPU sec, 2.750 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 280573, 18, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 235, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 561)
[M::mem_pestat] mean and std.dev: (221.62, 106.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 694)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 316, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 891)
[M::mem_pestat] mean and std.dev: (333.31, 155.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1118)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (882, 1072, 1685)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3291)
[M::mem_pestat] mean and std.dev: (1186.88, 777.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4297)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 218, 382)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 812)
[M::mem_pestat] mean and std.dev: (226.69, 99.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1027)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681262 reads in 158.972 CPU sec, 5.045 real sec
[M::process] read 681266 sequences (100000187 bp) in 1.875 CPU sec, 1.888 real sec...
sorting block 15, #reads = 1073696 mem = 536878589 peak = 883900416
[M::mem_process_seqs] Processed 681078 reads in 104.829 CPU sec, 3.310 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 280808, 9, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 263, 1571)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4321)
[M::mem_pestat] mean and std.dev: (742.92, 925.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5696)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 320, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 902)
[M::mem_pestat] mean and std.dev: (337.39, 158.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1132)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (258, 287, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 897)
[M::mem_pestat] mean and std.dev: (348.76, 209.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1186)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 16, #reads = 1073473 mem = 536878445 peak = 892923904
[M::process] read 684650 sequences (100000161 bp) in 2.996 CPU sec, 3.113 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 280389, 12, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 251, 563)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1329)
[M::mem_pestat] mean and std.dev: (318.72, 228.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1712)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 315, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 890)
[M::mem_pestat] mean and std.dev: (332.76, 156.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1117)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (286, 518, 1283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3277)
[M::mem_pestat] mean and std.dev: (525.80, 373.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4274)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 249, 661)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1603)
[M::mem_pestat] mean and std.dev: (468.88, 434.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2209)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680626 reads in 161.592 CPU sec, 5.124 real sec
[M::process] read 683892 sequences (100000037 bp) in 1.640 CPU sec, 1.641 real sec...
[M::mem_process_seqs] Processed 681266 reads in 106.869 CPU sec, 3.383 real sec
sorting block 17, #reads = 1074193 mem = 536882956 peak = 892923904
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 281205, 8, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (115, 166, 240)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 490)
[M::mem_pestat] mean and std.dev: (167.43, 67.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 615)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 297, 413)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 847)
[M::mem_pestat] mean and std.dev: (315.18, 149.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1064)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 223, 733)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1867)
[M::mem_pestat] mean and std.dev: (429.03, 407.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2434)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683294 sequences (100000135 bp) in 2.721 CPU sec, 2.840 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 281092, 19, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 236, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 638)
[M::mem_pestat] mean and std.dev: (232.33, 96.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 805)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 301, 419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 859)
[M::mem_pestat] mean and std.dev: (319.09, 150.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1079)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (634, 924, 2377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5863)
[M::mem_pestat] mean and std.dev: (1348.37, 992.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7606)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 291, 400)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 876)
[M::mem_pestat] mean and std.dev: (301.67, 166.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1114)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684650 reads in 156.182 CPU sec, 4.958 real sec
[M::process] read 682806 sequences (100000091 bp) in 1.934 CPU sec, 1.954 real sec...
[M::mem_process_seqs] Processed 683892 reads in 100.664 CPU sec, 3.172 real sec
sorting block 18, #reads = 1075378 mem = 536880716 peak = 892923904
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 281220, 11, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 350, 557)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1375)
[M::mem_pestat] mean and std.dev: (383.60, 261.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1784)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 303, 419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 853)
[M::mem_pestat] mean and std.dev: (320.45, 150.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1070)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (819, 868, 2092)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4638)
[M::mem_pestat] mean and std.dev: (1481.45, 1414.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7141)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 242, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 625)
[M::mem_pestat] mean and std.dev: (265.59, 118.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 765)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682502 sequences (100000139 bp) in 2.887 CPU sec, 3.016 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 281269, 17, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 222, 486)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1132)
[M::mem_pestat] mean and std.dev: (269.93, 196.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1455)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 305, 419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 851)
[M::mem_pestat] mean and std.dev: (321.02, 148.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1067)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1484, 2606, 2637)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4943)
[M::mem_pestat] mean and std.dev: (2184.59, 931.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6096)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 287, 405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 869)
[M::mem_pestat] mean and std.dev: (277.07, 137.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1101)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683294 reads in 153.456 CPU sec, 4.879 real sec
[M::mem_process_seqs] Processed 682806 reads in 98.958 CPU sec, 3.118 real sec
sorting block 19, #reads = 1078561 mem = 536878248 peak = 892923904
[M::process] read 682516 sequences (100000295 bp) in 2.193 CPU sec, 2.263 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 281201, 14, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 314, 475)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1033)
[M::mem_pestat] mean and std.dev: (349.21, 186.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1312)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 307, 423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 859)
[M::mem_pestat] mean and std.dev: (323.33, 149.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1077)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (374, 492, 1758)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4526)
[M::mem_pestat] mean and std.dev: (889.92, 953.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5910)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 441, 586)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1294)
[M::mem_pestat] mean and std.dev: (447.65, 299.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1648)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 20, #reads = 1077953 mem = 536877657 peak = 892923904
[M::process] read 682058 sequences (100000114 bp) in 2.546 CPU sec, 2.670 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 280983, 11, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 184, 241)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 417)
[M::mem_pestat] mean and std.dev: (187.80, 70.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 505)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 308, 424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 862)
[M::mem_pestat] mean and std.dev: (324.19, 150.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1081)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (658, 967, 967)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (40, 1585)
[M::mem_pestat] mean and std.dev: (797.09, 241.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1894)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 243, 390)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (290.57, 149.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 939)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682502 reads in 155.975 CPU sec, 4.969 real sec
[M::process] read 681956 sequences (100000102 bp) in 2.307 CPU sec, 2.380 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 281279, 14, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 456, 807)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1999)
[M::mem_pestat] mean and std.dev: (395.67, 253.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2595)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 310, 426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 864)
[M::mem_pestat] mean and std.dev: (325.83, 150.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1083)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (541, 633, 633)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (357, 817)
[M::mem_pestat] mean and std.dev: (574.27, 104.07)
[M::mem_pestat] low and high boundaries for proper pairs: (158, 991)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 341, 498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1106)
[M::mem_pestat] mean and std.dev: (341.72, 183.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1410)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682058 reads in 87.972 CPU sec, 2.773 real sec
[M::process] read 682014 sequences (100000149 bp) in 2.033 CPU sec, 2.069 real sec...
sorting block 21, #reads = 1076879 mem = 536879978 peak = 892923904
[M::mem_process_seqs] Processed 682516 reads in 223.558 CPU sec, 7.070 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 281243, 10, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 190, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (192.23, 96.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 840)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 313, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 874)
[M::mem_pestat] mean and std.dev: (328.89, 152.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1096)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (948, 1017, 1017)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (810, 1155)
[M::mem_pestat] mean and std.dev: (999.75, 29.88)
[M::mem_pestat] low and high boundaries for proper pairs: (741, 1224)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 308, 1141)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2935)
[M::mem_pestat] mean and std.dev: (647.68, 593.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3832)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681768 sequences (100000236 bp) in 2.601 CPU sec, 2.744 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281140, 8, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 196, 417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 979)
[M::mem_pestat] mean and std.dev: (242.51, 127.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1260)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 313, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 874)
[M::mem_pestat] mean and std.dev: (328.87, 152.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1096)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 264, 423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 815)
[M::mem_pestat] mean and std.dev: (284.80, 155.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1011)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681956 reads in 179.350 CPU sec, 5.677 real sec
sorting block 22, #reads = 1078430 mem = 536881421 peak = 892923904
[M::process] read 681288 sequences (100000186 bp) in 2.262 CPU sec, 2.348 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 280970, 4, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 336, 421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 937)
[M::mem_pestat] mean and std.dev: (288.51, 143.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1195)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 315, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 875)
[M::mem_pestat] mean and std.dev: (329.48, 152.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1097)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 291, 893)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2301)
[M::mem_pestat] mean and std.dev: (475.70, 452.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3005)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681270 sequences (100000098 bp) in 1.957 CPU sec, 1.958 real sec...
[M::mem_process_seqs] Processed 681768 reads in 97.645 CPU sec, 3.084 real sec
sorting block 23, #reads = 1077526 mem = 536879457 peak = 892923904
[M::mem_process_seqs] Processed 682014 reads in 237.994 CPU sec, 7.536 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 281184, 2, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (129, 248, 524)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1314)
[M::mem_pestat] mean and std.dev: (278.32, 177.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1709)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 316, 434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 882)
[M::mem_pestat] mean and std.dev: (331.65, 153.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1106)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 263, 507)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1201)
[M::mem_pestat] mean and std.dev: (279.00, 154.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1548)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681152 sequences (100000010 bp) in 2.647 CPU sec, 2.792 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 280945, 13, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 312, 793)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1883)
[M::mem_pestat] mean and std.dev: (446.36, 302.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2428)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 317, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 883)
[M::mem_pestat] mean and std.dev: (332.53, 153.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1107)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (910, 955, 2464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5572)
[M::mem_pestat] mean and std.dev: (1374.38, 928.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7126)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 258, 421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 841)
[M::mem_pestat] mean and std.dev: (303.12, 137.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1051)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681288 reads in 192.314 CPU sec, 6.095 real sec
sorting block 24, #reads = 1076274 mem = 536879504 peak = 892923904
[M::process] read 681244 sequences (100000067 bp) in 2.098 CPU sec, 2.123 real sec...
[M::mem_process_seqs] Processed 681270 reads in 115.497 CPU sec, 3.635 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (15, 281503, 8, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 240, 684)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1678)
[M::mem_pestat] mean and std.dev: (355.29, 259.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2175)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 317, 433)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 877)
[M::mem_pestat] mean and std.dev: (331.62, 152.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1099)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 347, 559)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1319)
[M::mem_pestat] mean and std.dev: (333.05, 214.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1699)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 25, #reads = 1076824 mem = 536878971 peak = 911355904
[M::process] read 680884 sequences (100000218 bp) in 2.705 CPU sec, 2.867 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 281260, 20, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 257, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 663)
[M::mem_pestat] mean and std.dev: (252.20, 87.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 814)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 318, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 889)
[M::mem_pestat] mean and std.dev: (334.08, 155.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1115)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 580, 942)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2362)
[M::mem_pestat] mean and std.dev: (744.95, 607.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3176)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 279, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 970)
[M::mem_pestat] mean and std.dev: (302.12, 137.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1228)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681352 sequences (100000101 bp) in 1.730 CPU sec, 1.726 real sec...
[M::mem_process_seqs] Processed 681152 reads in 176.174 CPU sec, 5.602 real sec
[M::mem_process_seqs] Processed 681244 reads in 114.398 CPU sec, 3.625 real sec
sorting block 26, #reads = 1077291 mem = 536878323 peak = 911355904
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 280874, 9, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 284, 502)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1124)
[M::mem_pestat] mean and std.dev: (337.17, 189.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1435)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 315, 429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 865)
[M::mem_pestat] mean and std.dev: (330.03, 151.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1083)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 248, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 599)
[M::mem_pestat] mean and std.dev: (237.26, 106.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 742)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680758 sequences (100000176 bp) in 2.623 CPU sec, 2.738 real sec...
[M::process] read 680768 sequences (100000126 bp) in 1.600 CPU sec, 1.602 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 281078, 13, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 196, 417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 875)
[M::mem_pestat] mean and std.dev: (221.33, 100.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1104)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 316, 434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 882)
[M::mem_pestat] mean and std.dev: (331.37, 153.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1106)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (591, 591, 763)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (247, 1107)
[M::mem_pestat] mean and std.dev: (626.42, 123.02)
[M::mem_pestat] low and high boundaries for proper pairs: (75, 1279)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 216, 775)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1987)
[M::mem_pestat] mean and std.dev: (356.86, 280.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2593)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680884 reads in 181.496 CPU sec, 5.779 real sec
[M::mem_process_seqs] Processed 681352 reads in 117.454 CPU sec, 3.726 real sec
sorting block 27, #reads = 1075981 mem = 536879240 peak = 911355904
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 281073, 13, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 227, 405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 929)
[M::mem_pestat] mean and std.dev: (312.29, 234.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1248)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 318, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 889)
[M::mem_pestat] mean and std.dev: (333.44, 154.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1115)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (910, 2458, 2458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5554)
[M::mem_pestat] mean and std.dev: (1621.08, 973.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7102)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 284, 413)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 873)
[M::mem_pestat] mean and std.dev: (266.68, 127.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1103)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680746 sequences (100000197 bp) in 3.057 CPU sec, 3.182 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 280195, 16, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 244, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 779)
[M::mem_pestat] mean and std.dev: (279.15, 167.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 988)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 316, 433)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 875)
[M::mem_pestat] mean and std.dev: (331.47, 152.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1096)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (487, 510, 1584)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3778)
[M::mem_pestat] mean and std.dev: (1107.12, 965.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4968)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 297, 823)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2079)
[M::mem_pestat] mean and std.dev: (595.29, 544.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2774)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682322 sequences (100000140 bp) in 1.999 CPU sec, 2.009 real sec...
[M::mem_process_seqs] Processed 680758 reads in 186.663 CPU sec, 5.915 real sec
sorting block 28, #reads = 1077033 mem = 536878970 peak = 911355904
[M::mem_process_seqs] Processed 680768 reads in 120.646 CPU sec, 3.818 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 280140, 11, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 447, 831)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2031)
[M::mem_pestat] mean and std.dev: (637.86, 646.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3225)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 317, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 886)
[M::mem_pestat] mean and std.dev: (333.58, 154.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1111)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1986, 1986, 2653)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (652, 3987)
[M::mem_pestat] mean and std.dev: (1943.18, 681.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4670)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 270, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 582)
[M::mem_pestat] mean and std.dev: (249.77, 78.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 708)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680848 sequences (100000301 bp) in 2.763 CPU sec, 2.892 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 281035, 12, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 272, 602)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1442)
[M::mem_pestat] mean and std.dev: (367.00, 268.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1862)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 681170 sequences (100000084 bp) in 1.919 CPU sec, 1.921 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (204, 307, 427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 873)
[M::mem_pestat] mean and std.dev: (325.72, 153.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1096)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 171, 763)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2019)
[M::mem_pestat] mean and std.dev: (339.18, 285.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2647)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 327, 427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 795)
[M::mem_pestat] mean and std.dev: (279.56, 114.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 979)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680746 reads in 188.398 CPU sec, 5.982 real sec
sorting block 29, #reads = 1075411 mem = 536879358 peak = 911355904
[M::mem_process_seqs] Processed 682322 reads in 121.942 CPU sec, 3.877 real sec
sorting block 30, #reads = 1075247 mem = 536878108 peak = 911355904
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 280316, 11, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 225, 262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (31, 416)
[M::mem_pestat] mean and std.dev: (203.15, 51.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 493)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 317, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 881)
[M::mem_pestat] mean and std.dev: (332.96, 153.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1104)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (23, 625, 6932)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 20750)
[M::mem_pestat] mean and std.dev: (2191.91, 2929.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 27659)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 164, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 459)
[M::mem_pestat] mean and std.dev: (188.03, 63.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 560)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681430 sequences (100000230 bp) in 2.754 CPU sec, 2.881 real sec...
[M::process] read 681130 sequences (100000301 bp) in 1.750 CPU sec, 1.750 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 280229, 6, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 193, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 775)
[M::mem_pestat] mean and std.dev: (230.86, 135.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 989)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 313, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 872)
[M::mem_pestat] mean and std.dev: (329.64, 152.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1093)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 267, 640)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1502)
[M::mem_pestat] mean and std.dev: (355.64, 220.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1933)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680848 reads in 189.864 CPU sec, 6.037 real sec
[M::mem_process_seqs] Processed 681170 reads in 121.859 CPU sec, 3.867 real sec
sorting block 31, #reads = 1075057 mem = 536883470 peak = 911355904
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 281073, 5, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (269, 296, 478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 896)
[M::mem_pestat] mean and std.dev: (294.41, 113.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1105)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 312, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 874)
[M::mem_pestat] mean and std.dev: (328.85, 152.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1096)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 268, 400)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (315.88, 142.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 940)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681214 sequences (100000182 bp) in 2.840 CPU sec, 2.971 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 280454, 16, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 253, 292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 564)
[M::mem_pestat] mean and std.dev: (231.25, 94.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 700)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 314, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 878)
[M::mem_pestat] mean and std.dev: (330.72, 153.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1101)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (430, 853, 1282)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2986)
[M::mem_pestat] mean and std.dev: (753.12, 476.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3838)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 328, 512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1168)
[M::mem_pestat] mean and std.dev: (329.39, 175.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1496)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681136 sequences (100000147 bp) in 2.020 CPU sec, 2.017 real sec...
[M::mem_process_seqs] Processed 681430 reads in 185.589 CPU sec, 5.889 real sec
[M::mem_process_seqs] Processed 681130 reads in 120.252 CPU sec, 3.805 real sec
sorting block 32, #reads = 1076077 mem = 536877068 peak = 911355904
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 281075, 4, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 239, 600)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1510)
[M::mem_pestat] mean and std.dev: (356.21, 265.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1965)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 312, 429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 869)
[M::mem_pestat] mean and std.dev: (329.18, 152.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1089)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 246, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 602)
[M::mem_pestat] mean and std.dev: (240.27, 88.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 739)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680946 sequences (100000275 bp) in 2.650 CPU sec, 2.749 real sec...
[M::process] read 681062 sequences (100000026 bp) in 1.930 CPU sec, 1.930 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 280655, 4, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 301, 398)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 776)
[M::mem_pestat] mean and std.dev: (293.15, 142.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 965)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 314, 433)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 881)
[M::mem_pestat] mean and std.dev: (330.82, 154.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1105)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 261, 519)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1163)
[M::mem_pestat] mean and std.dev: (268.57, 121.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1485)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681214 reads in 185.512 CPU sec, 5.893 real sec
sorting block 33, #reads = 1074658 mem = 536883766 peak = 911355904
[M::mem_process_seqs] Processed 681136 reads in 120.883 CPU sec, 3.835 real sec
sorting block 34, #reads = 1074938 mem = 536880392 peak = 911355904
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 280693, 6, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 481, 491)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1109)
[M::mem_pestat] mean and std.dev: (385.66, 193.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1418)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 315, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 885)
[M::mem_pestat] mean and std.dev: (332.97, 155.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1110)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 197, 512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1238)
[M::mem_pestat] mean and std.dev: (322.18, 254.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1601)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680944 sequences (100000243 bp) in 2.597 CPU sec, 2.689 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 281222, 17, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 316, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 950)
[M::mem_pestat] mean and std.dev: (338.03, 188.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1199)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 684172 sequences (100000214 bp) in 2.030 CPU sec, 2.032 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (210, 317, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 897)
[M::mem_pestat] mean and std.dev: (334.67, 157.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1126)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (384, 641, 1007)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2253)
[M::mem_pestat] mean and std.dev: (466.29, 254.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2876)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 240, 475)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1057)
[M::mem_pestat] mean and std.dev: (282.93, 179.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1348)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680946 reads in 184.989 CPU sec, 5.872 real sec
[M::mem_process_seqs] Processed 681062 reads in 120.398 CPU sec, 3.815 real sec
sorting block 35, #reads = 1073828 mem = 536876298 peak = 911355904
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 281051, 6, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 256, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 901)
[M::mem_pestat] mean and std.dev: (277.70, 170.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1147)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 320, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 904)
[M::mem_pestat] mean and std.dev: (337.04, 158.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1135)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 327, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 924)
[M::mem_pestat] mean and std.dev: (309.42, 111.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1157)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 684012 sequences (100000034 bp) in 2.657 CPU sec, 2.796 real sec...
[M::process] read 682994 sequences (100000239 bp) in 1.711 CPU sec, 1.721 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281849, 12, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 192, 377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 827)
[M::mem_pestat] mean and std.dev: (227.24, 111.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1052)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 298, 414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 846)
[M::mem_pestat] mean and std.dev: (316.62, 149.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1062)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (384, 2457, 2609)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7059)
[M::mem_pestat] mean and std.dev: (1531.75, 1180.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9284)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 318, 662)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1598)
[M::mem_pestat] mean and std.dev: (421.20, 307.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2066)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680944 reads in 186.024 CPU sec, 5.918 real sec
[M::mem_process_seqs] Processed 684172 reads in 118.920 CPU sec, 3.786 real sec
sorting block 36, #reads = 1073872 mem = 536878537 peak = 911355904
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 281958, 5, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 244, 477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1021)
[M::mem_pestat] mean and std.dev: (284.81, 134.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1293)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 301, 417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 853)
[M::mem_pestat] mean and std.dev: (318.29, 149.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1071)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 278, 520)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1288)
[M::mem_pestat] mean and std.dev: (293.09, 153.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1672)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682648 sequences (100000217 bp) in 2.615 CPU sec, 2.732 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (17, 280910, 10, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 210, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 589)
[M::mem_pestat] mean and std.dev: (212.47, 64.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 730)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 305, 420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 854)
[M::mem_pestat] mean and std.dev: (321.01, 149.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1071)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (101, 700, 1068)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3002)
[M::mem_pestat] mean and std.dev: (442.62, 407.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3969)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 173, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (225.10, 111.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 959)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682386 sequences (100000189 bp) in 1.920 CPU sec, 1.914 real sec...
[M::mem_process_seqs] Processed 684012 reads in 176.204 CPU sec, 5.605 real sec
[M::mem_process_seqs] Processed 682994 reads in 113.445 CPU sec, 3.595 real sec
sorting block 37, #reads = 1079223 mem = 536880082 peak = 911355904
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 281455, 10, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 261, 417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 941)
[M::mem_pestat] mean and std.dev: (234.16, 126.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1203)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 306, 422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 858)
[M::mem_pestat] mean and std.dev: (322.42, 149.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1076)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 383, 728)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1852)
[M::mem_pestat] mean and std.dev: (352.25, 236.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2414)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 220, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 675)
[M::mem_pestat] mean and std.dev: (244.79, 109.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 846)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682156 sequences (100000163 bp) in 2.993 CPU sec, 3.107 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281656, 13, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 304, 910)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2386)
[M::mem_pestat] mean and std.dev: (392.05, 304.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3124)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 308, 423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 857)
[M::mem_pestat] mean and std.dev: (323.79, 149.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1074)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (827, 1686, 2890)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7016)
[M::mem_pestat] mean and std.dev: (1706.15, 1046.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9079)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 242, 557)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1409)
[M::mem_pestat] mean and std.dev: (317.81, 251.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1835)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681976 sequences (100000084 bp) in 1.845 CPU sec, 1.849 real sec...
[M::mem_process_seqs] Processed 682648 reads in 175.251 CPU sec, 5.562 real sec
sorting block 38, #reads = 1076462 mem = 536881485 peak = 911355904
[M::mem_process_seqs] Processed 682386 reads in 112.071 CPU sec, 3.546 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 281184, 15, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 221, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 726)
[M::mem_pestat] mean and std.dev: (233.85, 112.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 916)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 311, 427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 869)
[M::mem_pestat] mean and std.dev: (326.52, 151.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1090)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1629, 2153, 2153)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (581, 3201)
[M::mem_pestat] mean and std.dev: (2019.46, 302.44)
[M::mem_pestat] low and high boundaries for proper pairs: (57, 3725)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 348, 663)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1583)
[M::mem_pestat] mean and std.dev: (358.18, 223.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2043)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 39, #reads = 1077244 mem = 536881031 peak = 950919168
[M::process] read 681942 sequences (100000216 bp) in 2.689 CPU sec, 2.785 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 281026, 8, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 336, 930)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2438)
[M::mem_pestat] mean and std.dev: (487.07, 326.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3192)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 312, 429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 873)
[M::mem_pestat] mean and std.dev: (327.91, 152.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1095)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 331, 408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 846)
[M::mem_pestat] mean and std.dev: (301.42, 120.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1065)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681588 sequences (100000110 bp) in 1.889 CPU sec, 1.889 real sec...
[M::mem_process_seqs] Processed 682156 reads in 175.031 CPU sec, 5.569 real sec
[M::mem_process_seqs] Processed 681976 reads in 114.880 CPU sec, 3.637 real sec
sorting block 40, #reads = 1076735 mem = 536878303 peak = 950919168
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 281302, 10, 20)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 248, 531)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1295)
[M::mem_pestat] mean and std.dev: (336.42, 237.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1677)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 312, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 874)
[M::mem_pestat] mean and std.dev: (328.39, 152.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1096)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 493, 1283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3451)
[M::mem_pestat] mean and std.dev: (664.80, 559.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4535)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 207, 394)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 872)
[M::mem_pestat] mean and std.dev: (248.94, 146.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1111)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681456 sequences (100000048 bp) in 2.934 CPU sec, 3.053 real sec...
[M::process] read 681024 sequences (100000112 bp) in 1.519 CPU sec, 1.526 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 280777, 4, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 237, 477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1085)
[M::mem_pestat] mean and std.dev: (280.69, 149.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1389)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 315, 434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 884)
[M::mem_pestat] mean and std.dev: (331.25, 154.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1109)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 256, 1334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3612)
[M::mem_pestat] mean and std.dev: (615.65, 853.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4751)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681942 reads in 172.498 CPU sec, 5.487 real sec
[M::mem_process_seqs] Processed 681588 reads in 113.492 CPU sec, 3.607 real sec
sorting block 41, #reads = 1076982 mem = 536880572 peak = 950919168
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 281076, 2, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 230, 414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 914)
[M::mem_pestat] mean and std.dev: (270.44, 126.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1164)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 317, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 893)
[M::mem_pestat] mean and std.dev: (333.05, 155.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1121)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 283, 527)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1205)
[M::mem_pestat] mean and std.dev: (299.32, 203.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1544)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680960 sequences (100000074 bp) in 2.653 CPU sec, 2.777 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 280742, 15, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 209, 515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1207)
[M::mem_pestat] mean and std.dev: (331.02, 266.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1553)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 319, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 889)
[M::mem_pestat] mean and std.dev: (334.42, 155.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1115)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (498, 538, 3049)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8151)
[M::mem_pestat] mean and std.dev: (1599.00, 1353.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10702)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 228, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1032)
[M::mem_pestat] mean and std.dev: (267.38, 134.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1321)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680832 sequences (100000200 bp) in 1.829 CPU sec, 1.824 real sec...
[M::mem_process_seqs] Processed 681456 reads in 173.725 CPU sec, 5.535 real sec
sorting block 42, #reads = 1076012 mem = 536879837 peak = 950919168
[M::mem_process_seqs] Processed 681024 reads in 114.214 CPU sec, 3.626 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281130, 23, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 260, 567)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1415)
[M::mem_pestat] mean and std.dev: (293.79, 173.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1839)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 319, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 890)
[M::mem_pestat] mean and std.dev: (334.63, 155.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1116)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (605, 879, 971)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1703)
[M::mem_pestat] mean and std.dev: (742.45, 317.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2069)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 262, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 732)
[M::mem_pestat] mean and std.dev: (253.49, 89.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 911)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680790 sequences (100000155 bp) in 3.115 CPU sec, 3.225 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 281001, 8, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 290, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 549)
[M::mem_pestat] mean and std.dev: (253.65, 93.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 666)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 319, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 884)
[M::mem_pestat] mean and std.dev: (333.71, 154.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1108)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 514, 667)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1583)
[M::mem_pestat] mean and std.dev: (518.51, 371.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2041)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680616 sequences (100000261 bp) in 1.969 CPU sec, 1.972 real sec...
[M::mem_process_seqs] Processed 680960 reads in 174.248 CPU sec, 5.526 real sec
sorting block 43, #reads = 1075271 mem = 536879774 peak = 950919168
[M::mem_process_seqs] Processed 680832 reads in 112.635 CPU sec, 3.565 real sec
sorting block 44, #reads = 1076361 mem = 536878058 peak = 996118528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 281091, 16, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 195, 266)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 482)
[M::mem_pestat] mean and std.dev: (199.52, 59.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 590)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 319, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 882)
[M::mem_pestat] mean and std.dev: (334.29, 154.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1105)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 1646, 2461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7017)
[M::mem_pestat] mean and std.dev: (1498.19, 1344.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9295)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 333, 703)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1749)
[M::mem_pestat] mean and std.dev: (421.44, 257.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2272)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680388 sequences (100000145 bp) in 2.755 CPU sec, 2.855 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 280427, 9, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 257, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 570)
[M::mem_pestat] mean and std.dev: (233.56, 81.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 696)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 319, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 888)
[M::mem_pestat] mean and std.dev: (335.24, 155.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1113)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 295, 518)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1104)
[M::mem_pestat] mean and std.dev: (324.03, 188.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1397)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681210 sequences (100000169 bp) in 1.686 CPU sec, 1.684 real sec...
[M::mem_process_seqs] Processed 680790 reads in 176.309 CPU sec, 5.618 real sec
[M::mem_process_seqs] Processed 680616 reads in 115.798 CPU sec, 3.672 real sec
sorting block 45, #reads = 1076892 mem = 536879961 peak = 996118528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 280549, 9, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 295, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653)
[M::mem_pestat] mean and std.dev: (256.83, 91.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 806)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 317, 434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 876)
[M::mem_pestat] mean and std.dev: (332.78, 152.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1097)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 408, 1772)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4904)
[M::mem_pestat] mean and std.dev: (930.13, 1044.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6470)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680962 sequences (100000023 bp) in 2.807 CPU sec, 2.904 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 280600, 9, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 369, 496)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1118)
[M::mem_pestat] mean and std.dev: (382.41, 234.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1429)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 313, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 875)
[M::mem_pestat] mean and std.dev: (330.15, 153.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1097)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 265, 381)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 801)
[M::mem_pestat] mean and std.dev: (279.79, 179.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1011)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680848 sequences (100000140 bp) in 2.009 CPU sec, 2.005 real sec...
[M::mem_process_seqs] Processed 680388 reads in 179.229 CPU sec, 5.697 real sec
[M::mem_process_seqs] Processed 681210 reads in 119.444 CPU sec, 3.796 real sec
sorting block 46, #reads = 1076191 mem = 536877102 peak = 996118528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 281019, 5, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 242, 381)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (292.79, 165.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 969)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 312, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 872)
[M::mem_pestat] mean and std.dev: (329.60, 153.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1093)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 239, 561)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1237)
[M::mem_pestat] mean and std.dev: (288.45, 142.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1575)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681300 sequences (100000172 bp) in 2.342 CPU sec, 2.442 real sec...
[M::process] read 681326 sequences (100000243 bp) in 2.017 CPU sec, 2.025 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 280524, 7, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 265, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 968)
[M::mem_pestat] mean and std.dev: (292.88, 198.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1231)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 312, 428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 866)
[M::mem_pestat] mean and std.dev: (329.02, 152.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1085)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 220, 869)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2285)
[M::mem_pestat] mean and std.dev: (434.07, 338.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2993)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680962 reads in 180.027 CPU sec, 5.737 real sec
sorting block 47, #reads = 1074811 mem = 536881015 peak = 996118528
[M::mem_process_seqs] Processed 680848 reads in 117.669 CPU sec, 3.735 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 280587, 10, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 342, 945)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2475)
[M::mem_pestat] mean and std.dev: (518.62, 547.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3240)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 311, 429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 871)
[M::mem_pestat] mean and std.dev: (328.12, 152.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1092)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (366, 539, 1089)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2535)
[M::mem_pestat] mean and std.dev: (770.60, 583.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3258)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 330, 484)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1012)
[M::mem_pestat] mean and std.dev: (302.83, 159.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1276)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 48, #reads = 1076851 mem = 536877503 peak = 996118528
[M::process] read 681398 sequences (100000215 bp) in 2.977 CPU sec, 3.072 real sec...
[M::process] read 681354 sequences (100000087 bp) in 1.607 CPU sec, 1.610 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 280881, 6, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 284, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 639)
[M::mem_pestat] mean and std.dev: (268.89, 118.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 778)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 310, 428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 870)
[M::mem_pestat] mean and std.dev: (327.80, 152.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1091)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 356, 630)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1508)
[M::mem_pestat] mean and std.dev: (478.18, 367.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1949)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681300 reads in 180.920 CPU sec, 5.764 real sec
[M::mem_process_seqs] Processed 681326 reads in 119.732 CPU sec, 3.809 real sec
sorting block 49, #reads = 1075381 mem = 536881725 peak = 996118528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281093, 21, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (118, 238, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 649)
[M::mem_pestat] mean and std.dev: (211.39, 104.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 826)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 309, 426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 864)
[M::mem_pestat] mean and std.dev: (326.41, 151.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1083)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 418, 2364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6652)
[M::mem_pestat] mean and std.dev: (966.10, 978.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8796)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 320, 729)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1715)
[M::mem_pestat] mean and std.dev: (341.03, 225.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2208)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681404 sequences (100000127 bp) in 2.588 CPU sec, 2.687 real sec...
[M::process] read 681398 sequences (100000172 bp) in 1.746 CPU sec, 1.756 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 280966, 20, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 354, 739)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1899)
[M::mem_pestat] mean and std.dev: (396.29, 313.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2479)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 309, 426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 864)
[M::mem_pestat] mean and std.dev: (326.47, 152.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1083)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 616, 912)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2296)
[M::mem_pestat] mean and std.dev: (531.11, 418.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2988)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 229, 311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 603)
[M::mem_pestat] mean and std.dev: (245.36, 117.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 749)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681398 reads in 183.144 CPU sec, 5.847 real sec
[M::mem_process_seqs] Processed 681354 reads in 119.816 CPU sec, 3.814 real sec
sorting block 50, #reads = 1075428 mem = 536879241 peak = 996118528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281016, 8, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 231, 414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 892)
[M::mem_pestat] mean and std.dev: (238.24, 118.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1131)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 308, 424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 858)
[M::mem_pestat] mean and std.dev: (325.53, 151.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1075)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 298, 760)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1928)
[M::mem_pestat] mean and std.dev: (454.20, 362.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2512)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681180 sequences (100000225 bp) in 2.750 CPU sec, 2.838 real sec...
[M::process] read 681066 sequences (100000232 bp) in 1.680 CPU sec, 1.682 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 280616, 6, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 237, 625)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1593)
[M::mem_pestat] mean and std.dev: (246.79, 153.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2077)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 311, 428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 868)
[M::mem_pestat] mean and std.dev: (328.22, 153.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1088)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 264, 388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 708)
[M::mem_pestat] mean and std.dev: (254.62, 97.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681404 reads in 182.624 CPU sec, 5.817 real sec
[M::mem_process_seqs] Processed 681398 reads in 118.634 CPU sec, 3.777 real sec
sorting block 51, #reads = 1074917 mem = 536879130 peak = 996118528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 280906, 8, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 290, 412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 836)
[M::mem_pestat] mean and std.dev: (298.14, 157.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1048)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 312, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 874)
[M::mem_pestat] mean and std.dev: (329.70, 154.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1096)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 294, 377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (284.30, 117.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 839)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681218 sequences (100000209 bp) in 2.640 CPU sec, 2.742 real sec...
[M::process] read 680710 sequences (100000272 bp) in 1.518 CPU sec, 1.522 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 280838, 10, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 254, 451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1071)
[M::mem_pestat] mean and std.dev: (288.79, 217.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1381)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 315, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 893)
[M::mem_pestat] mean and std.dev: (333.61, 157.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1121)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (817, 1135, 2439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5683)
[M::mem_pestat] mean and std.dev: (1194.56, 755.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7305)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 321, 508)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1126)
[M::mem_pestat] mean and std.dev: (361.15, 250.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1435)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681180 reads in 180.129 CPU sec, 5.748 real sec
sorting block 52, #reads = 1075585 mem = 536882044 peak = 996118528
[M::mem_process_seqs] Processed 681066 reads in 116.854 CPU sec, 3.722 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 281007, 8, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 219, 491)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1077)
[M::mem_pestat] mean and std.dev: (292.21, 166.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1370)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 316, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 894)
[M::mem_pestat] mean and std.dev: (333.86, 156.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1122)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 302, 533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1135)
[M::mem_pestat] mean and std.dev: (317.88, 177.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1436)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 53, #reads = 1075408 mem = 536878583 peak = 996118528
[M::process] read 682342 sequences (100000078 bp) in 2.941 CPU sec, 3.026 real sec...
[M::process] read 683760 sequences (100000220 bp) in 1.624 CPU sec, 1.629 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 280115, 9, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 510, 831)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2035)
[M::mem_pestat] mean and std.dev: (599.00, 511.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2647)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 321, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 911)
[M::mem_pestat] mean and std.dev: (339.14, 160.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1144)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 302, 385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (291.65, 125.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 967)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681218 reads in 181.173 CPU sec, 5.773 real sec
[M::mem_process_seqs] Processed 680710 reads in 118.585 CPU sec, 3.776 real sec
sorting block 54, #reads = 1075258 mem = 536880186 peak = 996118528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 280679, 12, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 344, 755)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1783)
[M::mem_pestat] mean and std.dev: (448.39, 270.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2297)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 310, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 886)
[M::mem_pestat] mean and std.dev: (329.33, 156.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1113)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1240, 1240, 1672)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (376, 2536)
[M::mem_pestat] mean and std.dev: (1392.90, 446.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3180)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 353, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 992)
[M::mem_pestat] mean and std.dev: (347.16, 204.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1260)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683316 sequences (100000231 bp) in 3.220 CPU sec, 3.329 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281190, 3, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 297, 615)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1419)
[M::mem_pestat] mean and std.dev: (310.97, 175.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1821)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 302, 419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 857)
[M::mem_pestat] mean and std.dev: (320.08, 151.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1076)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 412, 531)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1165)
[M::mem_pestat] mean and std.dev: (362.68, 187.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1482)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682746 sequences (100000160 bp) in 1.953 CPU sec, 1.958 real sec...
[M::mem_process_seqs] Processed 682342 reads in 186.013 CPU sec, 5.915 real sec
[M::mem_process_seqs] Processed 683760 reads in 118.817 CPU sec, 3.762 real sec
sorting block 55, #reads = 1073277 mem = 536880051 peak = 996118528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 281272, 3, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (109, 168, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1168)
[M::mem_pestat] mean and std.dev: (241.32, 173.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1521)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 304, 421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 861)
[M::mem_pestat] mean and std.dev: (321.93, 152.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1081)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 273, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 917)
[M::mem_pestat] mean and std.dev: (311.23, 152.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1156)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682428 sequences (100000063 bp) in 3.544 CPU sec, 3.700 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 281417, 14, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 256, 857)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2203)
[M::mem_pestat] mean and std.dev: (465.12, 429.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2876)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 308, 428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 878)
[M::mem_pestat] mean and std.dev: (326.55, 155.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1103)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (371, 1176, 1250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3008)
[M::mem_pestat] mean and std.dev: (828.42, 450.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3887)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 276, 485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1079)
[M::mem_pestat] mean and std.dev: (307.30, 145.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1376)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683316 reads in 182.018 CPU sec, 5.788 real sec
[M::process] read 682212 sequences (100000111 bp) in 2.023 CPU sec, 2.042 real sec...
[M::mem_process_seqs] Processed 682746 reads in 119.108 CPU sec, 3.768 real sec
sorting block 56, #reads = 1078162 mem = 536882833 peak = 996118528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 281035, 5, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 465, 505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1163)
[M::mem_pestat] mean and std.dev: (357.93, 231.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1492)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 311, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 880)
[M::mem_pestat] mean and std.dev: (328.17, 154.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1105)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 312, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 660)
[M::mem_pestat] mean and std.dev: (288.41, 113.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 815)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 57, #reads = 1077274 mem = 536878320 peak = 996118528
[M::process] read 681926 sequences (100000279 bp) in 3.186 CPU sec, 3.353 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 280975, 20, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 224, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 818)
[M::mem_pestat] mean and std.dev: (222.92, 95.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1044)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 311, 427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 867)
[M::mem_pestat] mean and std.dev: (327.01, 152.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1087)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (712, 2047, 2702)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6682)
[M::mem_pestat] mean and std.dev: (1729.55, 1191.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8672)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 304, 879)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2187)
[M::mem_pestat] mean and std.dev: (369.36, 275.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2841)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682428 reads in 176.214 CPU sec, 5.644 real sec
[M::mem_process_seqs] Processed 682212 reads in 116.794 CPU sec, 3.692 real sec
[M::process] read 681586 sequences (100000220 bp) in 2.154 CPU sec, 2.191 real sec...
sorting block 58, #reads = 1078333 mem = 536878986 peak = 996118528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281188, 10, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 182, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 737)
[M::mem_pestat] mean and std.dev: (262.36, 193.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1035)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 312, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 882)
[M::mem_pestat] mean and std.dev: (329.53, 154.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1107)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (570, 591, 591)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (528, 633)
[M::mem_pestat] mean and std.dev: (585.00, 9.49)
[M::mem_pestat] low and high boundaries for proper pairs: (507, 654)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (284, 387, 503)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 941)
[M::mem_pestat] mean and std.dev: (380.94, 163.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1160)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681536 sequences (100000288 bp) in 2.632 CPU sec, 2.781 real sec...
[M::process] read 681490 sequences (100000277 bp) in 1.450 CPU sec, 1.452 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 280507, 11, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 220, 485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1189)
[M::mem_pestat] mean and std.dev: (270.41, 201.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1541)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 316, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 893)
[M::mem_pestat] mean and std.dev: (333.43, 156.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1121)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (642, 642, 1070)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1926)
[M::mem_pestat] mean and std.dev: (521.11, 304.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2354)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (260, 359, 920)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2240)
[M::mem_pestat] mean and std.dev: (545.62, 507.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2900)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681926 reads in 175.281 CPU sec, 5.595 real sec
[M::mem_process_seqs] Processed 681586 reads in 114.506 CPU sec, 3.642 real sec
sorting block 59, #reads = 1077272 mem = 536883021 peak = 996118528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 281016, 9, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (276, 563, 5166)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 14946)
[M::mem_pestat] mean and std.dev: (2052.96, 2273.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 19836)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 316, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 893)
[M::mem_pestat] mean and std.dev: (333.23, 156.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1121)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 343, 410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 804)
[M::mem_pestat] mean and std.dev: (316.61, 150.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1001)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681130 sequences (100000209 bp) in 2.418 CPU sec, 2.556 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 280781, 5, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (132, 218, 249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 483)
[M::mem_pestat] mean and std.dev: (186.24, 68.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 600)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 318, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 900)
[M::mem_pestat] mean and std.dev: (335.25, 157.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1130)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 204, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 796)
[M::mem_pestat] mean and std.dev: (223.79, 111.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1011)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681064 sequences (100000247 bp) in 1.950 CPU sec, 1.942 real sec...
[M::mem_process_seqs] Processed 681536 reads in 174.995 CPU sec, 5.576 real sec
[M::mem_process_seqs] Processed 681490 reads in 114.288 CPU sec, 3.628 real sec
sorting block 60, #reads = 1077364 mem = 536879410 peak = 996118528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 281331, 7, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 333, 523)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1243)
[M::mem_pestat] mean and std.dev: (368.88, 280.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1603)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 321, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 901)
[M::mem_pestat] mean and std.dev: (336.93, 157.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1131)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 190, 488)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1144)
[M::mem_pestat] mean and std.dev: (297.46, 240.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1472)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681032 sequences (100000283 bp) in 2.962 CPU sec, 3.079 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 280778, 8, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (253, 286, 427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 775)
[M::mem_pestat] mean and std.dev: (277.50, 82.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 319, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 898)
[M::mem_pestat] mean and std.dev: (335.99, 157.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1127)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 316, 648)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1456)
[M::mem_pestat] mean and std.dev: (354.02, 230.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1860)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681134 sequences (100000208 bp) in 1.970 CPU sec, 1.969 real sec...
[M::mem_process_seqs] Processed 681130 reads in 175.544 CPU sec, 5.567 real sec
sorting block 61, #reads = 1076888 mem = 536881778 peak = 996118528
[M::mem_process_seqs] Processed 681064 reads in 115.597 CPU sec, 3.656 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 280460, 9, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 244, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 717)
[M::mem_pestat] mean and std.dev: (271.03, 119.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 898)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 320, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 896)
[M::mem_pestat] mean and std.dev: (336.06, 156.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1124)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 219, 1001)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2641)
[M::mem_pestat] mean and std.dev: (556.58, 604.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3461)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 62, #reads = 1077031 mem = 536879674 peak = 998035456
[M::process] read 680696 sequences (100000217 bp) in 2.536 CPU sec, 2.663 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 280708, 14, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 334, 678)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1592)
[M::mem_pestat] mean and std.dev: (353.58, 225.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2049)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 318, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 889)
[M::mem_pestat] mean and std.dev: (334.25, 155.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1115)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (23, 783, 1424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4226)
[M::mem_pestat] mean and std.dev: (914.00, 897.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5627)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 318, 519)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1077)
[M::mem_pestat] mean and std.dev: (335.04, 196.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1356)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680680 sequences (100000152 bp) in 1.970 CPU sec, 1.978 real sec...
[M::mem_process_seqs] Processed 681032 reads in 174.610 CPU sec, 5.555 real sec
[M::mem_process_seqs] Processed 681134 reads in 114.590 CPU sec, 3.629 real sec
sorting block 63, #reads = 1077945 mem = 536881924 peak = 998035456
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 280342, 6, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 254, 526)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1188)
[M::mem_pestat] mean and std.dev: (366.66, 262.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1519)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 318, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 892)
[M::mem_pestat] mean and std.dev: (334.30, 155.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1119)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 313, 552)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1214)
[M::mem_pestat] mean and std.dev: (361.65, 265.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1545)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680376 sequences (100000019 bp) in 3.031 CPU sec, 3.142 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 280589, 7, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (267, 313, 952)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2322)
[M::mem_pestat] mean and std.dev: (448.96, 335.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3007)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 318, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 884)
[M::mem_pestat] mean and std.dev: (333.85, 154.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1108)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 302, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 985)
[M::mem_pestat] mean and std.dev: (287.52, 152.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1260)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681536 sequences (100000269 bp) in 1.968 CPU sec, 1.970 real sec...
[M::mem_process_seqs] Processed 680696 reads in 178.338 CPU sec, 5.662 real sec
[M::mem_process_seqs] Processed 680680 reads in 115.332 CPU sec, 3.648 real sec
sorting block 64, #reads = 1075740 mem = 536877149 peak = 998035456
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 280799, 5, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 215, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 782)
[M::mem_pestat] mean and std.dev: (241.37, 116.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 995)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 320, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 888)
[M::mem_pestat] mean and std.dev: (336.03, 155.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1113)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 285, 381)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 745)
[M::mem_pestat] mean and std.dev: (271.41, 105.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 927)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681760 sequences (100000099 bp) in 3.020 CPU sec, 3.124 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 280291, 6, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 210, 817)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2085)
[M::mem_pestat] mean and std.dev: (446.44, 474.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2719)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 309, 427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 869)
[M::mem_pestat] mean and std.dev: (326.76, 152.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1090)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 313, 634)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1628)
[M::mem_pestat] mean and std.dev: (435.75, 445.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2219)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681614 sequences (100000117 bp) in 1.854 CPU sec, 1.855 real sec...
[M::mem_process_seqs] Processed 680376 reads in 180.499 CPU sec, 5.743 real sec
[M::mem_process_seqs] Processed 681536 reads in 119.408 CPU sec, 3.797 real sec
sorting block 65, #reads = 1075541 mem = 536884269 peak = 998035456
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 281058, 8, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 205, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 743)
[M::mem_pestat] mean and std.dev: (214.56, 83.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 936)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 307, 424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 862)
[M::mem_pestat] mean and std.dev: (324.13, 150.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1081)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 263, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (61, 511)
[M::mem_pestat] mean and std.dev: (261.40, 83.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 601)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681410 sequences (100000255 bp) in 2.882 CPU sec, 3.005 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 280674, 11, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 234, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 676)
[M::mem_pestat] mean and std.dev: (257.31, 94.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 841)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 310, 429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 873)
[M::mem_pestat] mean and std.dev: (327.66, 152.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1095)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (276, 431, 1528)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4032)
[M::mem_pestat] mean and std.dev: (887.27, 923.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5284)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 235, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 730)
[M::mem_pestat] mean and std.dev: (249.25, 137.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 917)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681524 sequences (100000117 bp) in 1.907 CPU sec, 1.918 real sec...
[M::mem_process_seqs] Processed 681760 reads in 180.065 CPU sec, 5.734 real sec
sorting block 66, #reads = 1076243 mem = 536878533 peak = 998035456
[M::mem_process_seqs] Processed 681614 reads in 118.819 CPU sec, 3.764 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 280612, 13, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 222, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (211.69, 91.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 876)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 310, 427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 867)
[M::mem_pestat] mean and std.dev: (326.76, 151.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1087)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (5, 98, 2447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7331)
[M::mem_pestat] mean and std.dev: (978.54, 1229.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9773)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 292, 412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 816)
[M::mem_pestat] mean and std.dev: (276.09, 105.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1018)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 67, #reads = 1076640 mem = 536889211 peak = 998035456
[M::process] read 681668 sequences (100000031 bp) in 2.903 CPU sec, 3.023 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 280761, 3, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 170, 518)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1276)
[M::mem_pestat] mean and std.dev: (271.05, 219.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1655)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 308, 425)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 861)
[M::mem_pestat] mean and std.dev: (325.73, 151.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1079)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 323, 598)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1330)
[M::mem_pestat] mean and std.dev: (351.86, 191.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1696)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681512 sequences (100000212 bp) in 1.940 CPU sec, 1.938 real sec...
[M::mem_process_seqs] Processed 681410 reads in 183.243 CPU sec, 5.833 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 280629, 14, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 359, 961)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2433)
[M::mem_pestat] mean and std.dev: (649.14, 665.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3312)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 306, 422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 854)
[M::mem_pestat] mean and std.dev: (324.05, 150.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1070)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 1212, 2357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6583)
[M::mem_pestat] mean and std.dev: (1165.92, 907.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8696)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 296, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653)
[M::mem_pestat] mean and std.dev: (295.78, 139.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 855)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681226 sequences (100000190 bp) in 2.208 CPU sec, 2.211 real sec...
[M::mem_process_seqs] Processed 681668 reads in 99.563 CPU sec, 3.365 real sec
sorting block 68, #reads = 1075224 mem = 536878097 peak = 998035456
[M::mem_process_seqs] Processed 681524 reads in 240.055 CPU sec, 7.824 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 280608, 2, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 291, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 811)
[M::mem_pestat] mean and std.dev: (253.78, 126.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1036)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 308, 425)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 861)
[M::mem_pestat] mean and std.dev: (325.44, 150.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1079)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 214, 280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 512)
[M::mem_pestat] mean and std.dev: (208.75, 77.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 628)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 69, #reads = 1076365 mem = 536879452 peak = 998035456
[M::process] read 681332 sequences (100000017 bp) in 2.352 CPU sec, 2.462 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 281148, 9, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 267, 775)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1975)
[M::mem_pestat] mean and std.dev: (339.85, 297.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2575)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 311, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 874)
[M::mem_pestat] mean and std.dev: (328.89, 153.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1096)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 261, 597)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1513)
[M::mem_pestat] mean and std.dev: (323.79, 235.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1971)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681188 sequences (100000213 bp) in 1.960 CPU sec, 1.958 real sec...
[M::mem_process_seqs] Processed 681512 reads in 191.852 CPU sec, 6.084 real sec
[M::mem_process_seqs] Processed 681226 reads in 115.397 CPU sec, 3.653 real sec
sorting block 70, #reads = 1075157 mem = 536878220 peak = 998035456
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 280052, 4, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 419, 1218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3340)
[M::mem_pestat] mean and std.dev: (601.51, 490.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4401)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 310, 427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 867)
[M::mem_pestat] mean and std.dev: (327.61, 152.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1087)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 294, 522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1138)
[M::mem_pestat] mean and std.dev: (306.47, 131.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1446)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680190 sequences (100000005 bp) in 3.035 CPU sec, 3.243 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 280597, 11, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 215, 395)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 897)
[M::mem_pestat] mean and std.dev: (225.46, 130.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1148)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 313, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 880)
[M::mem_pestat] mean and std.dev: (330.43, 154.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1104)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 174, 174)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (174, 174)
[M::mem_pestat] mean and std.dev: (174.00, 0.00)
[M::mem_pestat] low and high boundaries for proper pairs: (174, 174)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 313, 544)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1204)
[M::mem_pestat] mean and std.dev: (362.36, 222.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1534)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681332 reads in 175.489 CPU sec, 5.573 real sec
[M::process] read 680708 sequences (100000238 bp) in 2.080 CPU sec, 2.097 real sec...
[M::mem_process_seqs] Processed 681188 reads in 115.970 CPU sec, 3.666 real sec
sorting block 71, #reads = 1074059 mem = 536878154 peak = 998035456
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 280861, 10, 17)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 235, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (252.36, 117.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 319, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 891)
[M::mem_pestat] mean and std.dev: (336.07, 156.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1117)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 323, 942)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2538)
[M::mem_pestat] mean and std.dev: (418.00, 326.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3336)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 308, 688)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1658)
[M::mem_pestat] mean and std.dev: (411.19, 361.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2143)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681154 sequences (100000008 bp) in 2.930 CPU sec, 3.052 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 280624, 8, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 255, 654)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1562)
[M::mem_pestat] mean and std.dev: (365.97, 244.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2016)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 320, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 902)
[M::mem_pestat] mean and std.dev: (336.94, 157.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1132)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 372, 532)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1082)
[M::mem_pestat] mean and std.dev: (354.07, 171.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1357)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 686868 sequences (100000264 bp) in 2.011 CPU sec, 2.020 real sec...
[M::mem_process_seqs] Processed 680190 reads in 175.902 CPU sec, 5.586 real sec
sorting block 72, #reads = 1075863 mem = 536878693 peak = 998035456
[M::mem_process_seqs] Processed 680708 reads in 118.414 CPU sec, 3.748 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 281144, 12, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 249, 579)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1439)
[M::mem_pestat] mean and std.dev: (325.25, 268.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1869)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 316, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 899)
[M::mem_pestat] mean and std.dev: (334.57, 158.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1129)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (488, 1795, 2585)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6779)
[M::mem_pestat] mean and std.dev: (1300.09, 976.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8876)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 339, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 829)
[M::mem_pestat] mean and std.dev: (314.56, 137.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1020)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 687200 sequences (100000172 bp) in 2.696 CPU sec, 2.894 real sec...
[M::process] read 686302 sequences (100000259 bp) in 1.667 CPU sec, 1.669 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 282982, 10, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 314, 1144)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3064)
[M::mem_pestat] mean and std.dev: (431.86, 400.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4024)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 286, 411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 857)
[M::mem_pestat] mean and std.dev: (309.97, 152.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1080)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (90, 1486, 2732)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8016)
[M::mem_pestat] mean and std.dev: (1516.44, 1601.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10658)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 304, 526)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1214)
[M::mem_pestat] mean and std.dev: (359.68, 226.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1558)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681154 reads in 190.174 CPU sec, 6.062 real sec
sorting block 73, #reads = 1074464 mem = 536883121 peak = 998035456
[M::mem_process_seqs] Processed 686868 reads in 129.452 CPU sec, 4.127 real sec
sorting block 74, #reads = 1075072 mem = 536882085 peak = 998035456
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 283274, 10, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 253, 434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 994)
[M::mem_pestat] mean and std.dev: (276.15, 187.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1274)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 285, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 853)
[M::mem_pestat] mean and std.dev: (308.53, 151.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1075)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (127, 2286, 3964)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11638)
[M::mem_pestat] mean and std.dev: (2908.70, 2861.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 15475)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 234, 920)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2316)
[M::mem_pestat] mean and std.dev: (500.48, 591.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3014)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 685736 sequences (100000301 bp) in 2.801 CPU sec, 2.943 real sec...
[M::process] read 684942 sequences (100000060 bp) in 1.605 CPU sec, 1.761 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 283242, 19, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 230, 991)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2649)
[M::mem_pestat] mean and std.dev: (311.35, 256.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3478)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 291, 418)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 874)
[M::mem_pestat] mean and std.dev: (313.94, 153.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1102)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (37, 705, 705)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2041)
[M::mem_pestat] mean and std.dev: (451.76, 437.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2709)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 181, 375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 847)
[M::mem_pestat] mean and std.dev: (268.28, 181.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1083)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 687200 reads in 192.075 CPU sec, 6.124 real sec
[M::mem_process_seqs] Processed 686302 reads in 123.548 CPU sec, 3.942 real sec
sorting block 75, #reads = 1075119 mem = 536880241 peak = 998035456
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 283584, 6, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 272, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 652)
[M::mem_pestat] mean and std.dev: (263.98, 111.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 815)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 295, 421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 879)
[M::mem_pestat] mean and std.dev: (316.53, 153.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1108)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 251, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 677)
[M::mem_pestat] mean and std.dev: (255.53, 93.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 832)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 684098 sequences (100000260 bp) in 3.043 CPU sec, 3.229 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 282464, 6, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 230, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 964)
[M::mem_pestat] mean and std.dev: (283.19, 187.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1221)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 299, 427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 893)
[M::mem_pestat] mean and std.dev: (320.25, 155.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1126)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 244, 290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (89, 424)
[M::mem_pestat] mean and std.dev: (263.42, 83.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 596)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 685736 reads in 191.601 CPU sec, 6.098 real sec
[M::process] read 683368 sequences (100000297 bp) in 2.475 CPU sec, 2.506 real sec...
[M::mem_process_seqs] Processed 684942 reads in 124.441 CPU sec, 3.927 real sec
sorting block 76, #reads = 1075973 mem = 536878743 peak = 998035456
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (15, 281996, 6, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 221, 298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (40, 470)
[M::mem_pestat] mean and std.dev: (241.77, 63.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 556)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 304, 429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 889)
[M::mem_pestat] mean and std.dev: (323.55, 154.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1119)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (264, 274, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 804)
[M::mem_pestat] mean and std.dev: (298.07, 118.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 984)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682696 sequences (100000046 bp) in 3.334 CPU sec, 3.480 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 281878, 11, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 236, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 678)
[M::mem_pestat] mean and std.dev: (265.91, 119.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 851)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 309, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 906)
[M::mem_pestat] mean and std.dev: (328.27, 157.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1141)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (294, 341, 2681)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7455)
[M::mem_pestat] mean and std.dev: (1602.45, 2233.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10536)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 300, 2345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6727)
[M::mem_pestat] mean and std.dev: (882.83, 1124.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8918)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684098 reads in 191.875 CPU sec, 6.117 real sec
[M::process] read 683028 sequences (100000075 bp) in 2.095 CPU sec, 2.106 real sec...
sorting block 77, #reads = 1075847 mem = 536881330 peak = 998035456
[M::mem_process_seqs] Processed 683368 reads in 125.384 CPU sec, 3.964 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 281554, 11, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 255, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 629)
[M::mem_pestat] mean and std.dev: (263.00, 72.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 766)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 314, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 918)
[M::mem_pestat] mean and std.dev: (332.84, 158.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1156)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1002, 1751, 4626)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11874)
[M::mem_pestat] mean and std.dev: (2135.36, 1664.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 15498)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 251, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 648)
[M::mem_pestat] mean and std.dev: (237.28, 82.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 802)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 78, #reads = 1075493 mem = 536881898 peak = 998035456
[M::process] read 682684 sequences (100000144 bp) in 2.866 CPU sec, 2.991 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (18, 282084, 7, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 177, 239)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 401)
[M::mem_pestat] mean and std.dev: (187.59, 43.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 482)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 315, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 918)
[M::mem_pestat] mean and std.dev: (332.97, 158.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1156)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 291, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 775)
[M::mem_pestat] mean and std.dev: (247.38, 120.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 980)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683142 sequences (100000189 bp) in 2.019 CPU sec, 2.028 real sec...
[M::mem_process_seqs] Processed 682696 reads in 181.672 CPU sec, 5.774 real sec
[M::mem_process_seqs] Processed 683028 reads in 118.548 CPU sec, 3.747 real sec
sorting block 79, #reads = 1075149 mem = 536882790 peak = 998035456
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 282170, 9, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (323, 502, 575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1079)
[M::mem_pestat] mean and std.dev: (433.81, 229.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1352)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 315, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 913)
[M::mem_pestat] mean and std.dev: (332.01, 157.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1149)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (278, 490, 681)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1487)
[M::mem_pestat] mean and std.dev: (443.62, 279.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1890)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683072 sequences (100000047 bp) in 3.063 CPU sec, 3.173 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 282153, 10, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 228, 278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (38, 438)
[M::mem_pestat] mean and std.dev: (199.93, 54.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 518)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 312, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 902)
[M::mem_pestat] mean and std.dev: (329.15, 155.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1135)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (741, 1307, 2572)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6234)
[M::mem_pestat] mean and std.dev: (1512.40, 1033.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8065)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 351, 1909)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5233)
[M::mem_pestat] mean and std.dev: (1334.93, 1767.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8404)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683098 sequences (100000150 bp) in 2.010 CPU sec, 2.008 real sec...
[M::mem_process_seqs] Processed 682684 reads in 178.390 CPU sec, 5.653 real sec
[M::mem_process_seqs] Processed 683142 reads in 115.791 CPU sec, 3.660 real sec
sorting block 80, #reads = 1074855 mem = 536878831 peak = 998035456
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 282205, 7, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 329, 527)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1185)
[M::mem_pestat] mean and std.dev: (297.86, 139.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1514)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 313, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 906)
[M::mem_pestat] mean and std.dev: (330.21, 155.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1140)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 270, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 638)
[M::mem_pestat] mean and std.dev: (268.89, 95.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 785)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682656 sequences (100000007 bp) in 2.697 CPU sec, 2.798 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 282228, 8, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 243, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1080)
[M::mem_pestat] mean and std.dev: (283.97, 137.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1384)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 313, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 905)
[M::mem_pestat] mean and std.dev: (329.79, 155.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1139)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (304, 400, 971)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2305)
[M::mem_pestat] mean and std.dev: (626.80, 463.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2972)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683050 sequences (100000196 bp) in 1.960 CPU sec, 1.964 real sec...
[M::mem_process_seqs] Processed 683072 reads in 179.664 CPU sec, 5.700 real sec
sorting block 81, #reads = 1072821 mem = 536878775 peak = 998035456
[M::mem_process_seqs] Processed 683098 reads in 116.994 CPU sec, 3.704 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 281543, 9, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (127, 154, 242)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 472)
[M::mem_pestat] mean and std.dev: (180.81, 75.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 587)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 313, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 900)
[M::mem_pestat] mean and std.dev: (329.87, 155.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1132)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 257, 763)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1933)
[M::mem_pestat] mean and std.dev: (444.03, 343.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2518)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682696 sequences (100000053 bp) in 3.092 CPU sec, 3.206 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281653, 4, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 268, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 738)
[M::mem_pestat] mean and std.dev: (274.55, 145.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 920)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 309, 434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 898)
[M::mem_pestat] mean and std.dev: (327.96, 155.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1130)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 261, 823)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2091)
[M::mem_pestat] mean and std.dev: (522.33, 458.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2725)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682180 sequences (100000262 bp) in 2.020 CPU sec, 2.016 real sec...
[M::mem_process_seqs] Processed 682656 reads in 179.250 CPU sec, 5.672 real sec
sorting block 82, #reads = 1073494 mem = 536881169 peak = 998035456
[M::mem_process_seqs] Processed 683050 reads in 119.630 CPU sec, 3.777 real sec
sorting block 83, #reads = 1073267 mem = 536878646 peak = 998035456
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 281598, 11, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 252, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 649)
[M::mem_pestat] mean and std.dev: (245.30, 95.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 799)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 312, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 906)
[M::mem_pestat] mean and std.dev: (330.28, 156.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1140)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (2257, 2257, 3975)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7411)
[M::mem_pestat] mean and std.dev: (2514.09, 1327.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9129)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 272, 732)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1912)
[M::mem_pestat] mean and std.dev: (341.93, 288.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2502)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682196 sequences (100000074 bp) in 2.701 CPU sec, 2.825 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 280710, 6, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (132, 180, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1086)
[M::mem_pestat] mean and std.dev: (208.94, 129.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1404)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 315, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 897)
[M::mem_pestat] mean and std.dev: (330.98, 154.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1127)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 340, 687)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1611)
[M::mem_pestat] mean and std.dev: (374.44, 210.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2073)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681668 sequences (100000122 bp) in 1.923 CPU sec, 1.929 real sec...
[M::mem_process_seqs] Processed 682696 reads in 180.508 CPU sec, 5.732 real sec
[M::mem_process_seqs] Processed 682180 reads in 120.985 CPU sec, 3.826 real sec
sorting block 84, #reads = 1072601 mem = 536879882 peak = 998035456
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 281768, 5, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 347, 680)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1586)
[M::mem_pestat] mean and std.dev: (473.02, 344.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2039)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 314, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 910)
[M::mem_pestat] mean and std.dev: (331.66, 156.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1145)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 366, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 897)
[M::mem_pestat] mean and std.dev: (298.47, 129.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1141)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682342 sequences (100000054 bp) in 3.058 CPU sec, 3.172 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 280782, 12, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 272, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 731)
[M::mem_pestat] mean and std.dev: (274.31, 156.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 922)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 318, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 921)
[M::mem_pestat] mean and std.dev: (335.55, 158.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1159)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1882, 1882, 4717)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10387)
[M::mem_pestat] mean and std.dev: (2688.67, 1765.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13222)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 426, 546)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1220)
[M::mem_pestat] mean and std.dev: (340.45, 122.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1557)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682316 sequences (100000169 bp) in 1.909 CPU sec, 1.913 real sec...
[M::mem_process_seqs] Processed 682196 reads in 181.042 CPU sec, 5.735 real sec
[M::mem_process_seqs] Processed 681668 reads in 120.637 CPU sec, 3.822 real sec
sorting block 85, #reads = 1073788 mem = 536879439 peak = 998035456
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 281512, 6, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 227, 558)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1264)
[M::mem_pestat] mean and std.dev: (276.77, 184.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1617)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 313, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 907)
[M::mem_pestat] mean and std.dev: (331.06, 156.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1141)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 263, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1059)
[M::mem_pestat] mean and std.dev: (300.29, 151.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1362)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681316 sequences (100000118 bp) in 2.498 CPU sec, 2.622 real sec...
[M::process] read 681348 sequences (100000155 bp) in 1.759 CPU sec, 1.757 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 280521, 6, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 269, 423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 899)
[M::mem_pestat] mean and std.dev: (273.48, 115.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1137)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 312, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 901)
[M::mem_pestat] mean and std.dev: (330.47, 156.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1133)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 288, 487)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1121)
[M::mem_pestat] mean and std.dev: (319.73, 174.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1438)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682342 reads in 186.322 CPU sec, 5.932 real sec
sorting block 86, #reads = 1072051 mem = 536878181 peak = 998035456
[M::mem_process_seqs] Processed 682316 reads in 125.365 CPU sec, 3.992 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 280868, 9, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 285, 406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 820)
[M::mem_pestat] mean and std.dev: (277.30, 113.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1027)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 317, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 904)
[M::mem_pestat] mean and std.dev: (333.84, 156.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1136)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 277, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (247.86, 110.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 967)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 87, #reads = 1072107 mem = 536879185 peak = 998035456
[M::process] read 681632 sequences (100000211 bp) in 2.787 CPU sec, 2.883 real sec...
[M::process] read 681090 sequences (100000054 bp) in 1.729 CPU sec, 1.738 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 281078, 6, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 231, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (222.82, 132.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 947)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 317, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 910)
[M::mem_pestat] mean and std.dev: (334.78, 157.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1144)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 444, 743)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1755)
[M::mem_pestat] mean and std.dev: (470.00, 393.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2261)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681316 reads in 181.853 CPU sec, 5.777 real sec
[M::mem_process_seqs] Processed 681348 reads in 121.979 CPU sec, 3.876 real sec
sorting block 88, #reads = 1071393 mem = 536879646 peak = 998035456
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 281309, 19, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 321, 581)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1389)
[M::mem_pestat] mean and std.dev: (299.62, 196.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1793)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 316, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 910)
[M::mem_pestat] mean and std.dev: (334.57, 157.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1144)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (394, 448, 2496)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6700)
[M::mem_pestat] mean and std.dev: (1287.58, 1512.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8802)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 366, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 892)
[M::mem_pestat] mean and std.dev: (340.81, 139.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1104)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680926 sequences (100000100 bp) in 2.854 CPU sec, 2.960 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 281238, 10, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (127, 210, 398)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 940)
[M::mem_pestat] mean and std.dev: (273.98, 190.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1211)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 320, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 921)
[M::mem_pestat] mean and std.dev: (337.91, 159.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1158)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (101, 548, 1290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3668)
[M::mem_pestat] mean and std.dev: (670.20, 781.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4857)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 339, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (278.55, 101.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 859)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 685668 sequences (100000279 bp) in 2.090 CPU sec, 2.094 real sec...
[M::mem_process_seqs] Processed 681632 reads in 183.749 CPU sec, 5.827 real sec
[M::mem_process_seqs] Processed 681090 reads in 122.512 CPU sec, 3.878 real sec
sorting block 89, #reads = 1072369 mem = 536879031 peak = 998035456
[M::process] read 689946 sequences (100000079 bp) in 3.039 CPU sec, 3.124 real sec...
[M::process] read 687738 sequences (100000280 bp) in 1.830 CPU sec, 1.839 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 282606, 2, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 301, 429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 851)
[M::mem_pestat] mean and std.dev: (282.22, 120.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1062)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 293, 420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 876)
[M::mem_pestat] mean and std.dev: (316.39, 154.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1104)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 270, 473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1095)
[M::mem_pestat] mean and std.dev: (304.58, 223.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1406)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 685668 reads in 109.262 CPU sec, 3.450 real sec
sorting block 90, #reads = 1071165 mem = 536883248 peak = 998035456
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 280828, 6, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 189, 281)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 559)
[M::mem_pestat] mean and std.dev: (181.31, 56.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 698)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 321, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 919)
[M::mem_pestat] mean and std.dev: (338.95, 159.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1155)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 405, 559)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1219)
[M::mem_pestat] mean and std.dev: (389.76, 191.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1549)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 284475, 8, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 259, 388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 794)
[M::mem_pestat] mean and std.dev: (263.43, 105.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 997)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 271, 390)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 812)
[M::mem_pestat] mean and std.dev: (294.74, 144.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1023)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 278, 2146)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6146)
[M::mem_pestat] mean and std.dev: (477.97, 593.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8146)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 687172 sequences (100000300 bp) in 2.372 CPU sec, 2.379 real sec...
[M::mem_process_seqs] Processed 680926 reads in 300.381 CPU sec, 9.525 real sec
[M::mem_process_seqs] Processed 689946 reads in 154.299 CPU sec, 4.921 real sec
sorting block 91, #reads = 1070829 mem = 536880985 peak = 998035456
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 283442, 10, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (128, 257, 738)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1958)
[M::mem_pestat] mean and std.dev: (418.82, 386.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2568)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 282, 401)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 831)
[M::mem_pestat] mean and std.dev: (302.93, 145.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1046)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 1129, 1486)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4184)
[M::mem_pestat] mean and std.dev: (842.00, 620.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5533)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 175, 250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 484)
[M::mem_pestat] mean and std.dev: (179.92, 68.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 601)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 686662 sequences (100000290 bp) in 2.927 CPU sec, 3.074 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 283594, 9, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 359, 477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1147)
[M::mem_pestat] mean and std.dev: (276.74, 176.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1482)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 285, 404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 836)
[M::mem_pestat] mean and std.dev: (305.52, 146.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1052)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 267, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (53, 493)
[M::mem_pestat] mean and std.dev: (247.72, 62.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 581)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 686466 sequences (100000223 bp) in 2.120 CPU sec, 2.121 real sec...
[M::mem_process_seqs] Processed 687738 reads in 196.637 CPU sec, 6.247 real sec
[M::mem_process_seqs] Processed 687172 reads in 129.575 CPU sec, 4.107 real sec
sorting block 92, #reads = 1070851 mem = 536878631 peak = 998035456
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 283009, 2, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (115, 168, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (220.09, 158.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 959)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 287, 405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 837)
[M::mem_pestat] mean and std.dev: (306.06, 145.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1053)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 273, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 628)
[M::mem_pestat] mean and std.dev: (265.00, 99.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 773)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 685772 sequences (100000283 bp) in 2.829 CPU sec, 3.004 real sec...
[M::process] read 685088 sequences (100000082 bp) in 2.230 CPU sec, 2.229 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 282986, 7, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 255, 384)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 836)
[M::mem_pestat] mean and std.dev: (254.34, 149.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1062)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 289, 405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 835)
[M::mem_pestat] mean and std.dev: (306.67, 144.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1050)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 323, 775)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1875)
[M::mem_pestat] mean and std.dev: (526.83, 499.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2525)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 686662 reads in 201.536 CPU sec, 6.394 real sec
sorting block 93, #reads = 1072033 mem = 536880226 peak = 998035456
[M::mem_process_seqs] Processed 686466 reads in 134.182 CPU sec, 4.258 real sec
sorting block 94, #reads = 1069630 mem = 536881135 peak = 998035456
[M::process] read 684390 sequences (100000068 bp) in 2.640 CPU sec, 2.757 real sec...
[M::process] read 684638 sequences (100000182 bp) in 2.064 CPU sec, 2.066 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 283094, 4, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 250, 412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 862)
[M::mem_pestat] mean and std.dev: (252.29, 120.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1087)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 296, 414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 854)
[M::mem_pestat] mean and std.dev: (313.61, 147.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1074)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 282, 512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1132)
[M::mem_pestat] mean and std.dev: (298.12, 153.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1442)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 685088 reads in 109.034 CPU sec, 3.454 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 282730, 15, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 477, 1106)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3026)
[M::mem_pestat] mean and std.dev: (712.03, 637.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3986)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 293, 412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 852)
[M::mem_pestat] mean and std.dev: (311.25, 147.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1072)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1207, 1990, 1990)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3556)
[M::mem_pestat] mean and std.dev: (1535.57, 782.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4664)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 284, 532)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1304)
[M::mem_pestat] mean and std.dev: (362.38, 298.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1690)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 282273, 4, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 292, 2002)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5576)
[M::mem_pestat] mean and std.dev: (809.28, 894.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7363)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 300, 420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 868)
[M::mem_pestat] mean and std.dev: (317.98, 150.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1092)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 272, 525)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1235)
[M::mem_pestat] mean and std.dev: (389.45, 276.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1590)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683940 sequences (100000158 bp) in 2.148 CPU sec, 2.157 real sec...
[M::mem_process_seqs] Processed 685772 reads in 294.746 CPU sec, 9.354 real sec
sorting block 95, #reads = 1070486 mem = 536877011 peak = 998035456
[M::mem_process_seqs] Processed 684390 reads in 144.454 CPU sec, 4.610 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 282418, 5, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 250, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (251.42, 125.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 851)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 299, 421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 873)
[M::mem_pestat] mean and std.dev: (317.30, 150.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1099)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 254, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (304.43, 187.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1055)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 96, #reads = 1071219 mem = 536882889 peak = 998035456
[M::process] read 683626 sequences (100000247 bp) in 2.653 CPU sec, 2.815 real sec...
[M::process] read 683698 sequences (100000016 bp) in 2.050 CPU sec, 2.046 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 282166, 18, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 273, 740)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1878)
[M::mem_pestat] mean and std.dev: (371.82, 334.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2447)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 303, 423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 873)
[M::mem_pestat] mean and std.dev: (320.13, 150.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1098)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1785, 2476, 2542)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (271, 4056)
[M::mem_pestat] mean and std.dev: (2191.56, 562.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4813)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 326, 756)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1904)
[M::mem_pestat] mean and std.dev: (464.03, 359.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2478)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684638 reads in 189.923 CPU sec, 6.036 real sec
[M::mem_process_seqs] Processed 683940 reads in 121.433 CPU sec, 3.857 real sec
sorting block 97, #reads = 1072384 mem = 536876690 peak = 998035456
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 282197, 4, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (132, 266, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1119)
[M::mem_pestat] mean and std.dev: (318.17, 213.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1448)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 306, 426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 876)
[M::mem_pestat] mean and std.dev: (322.33, 150.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1101)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 356, 434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 880)
[M::mem_pestat] mean and std.dev: (304.36, 153.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1103)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 684454 sequences (100000268 bp) in 2.650 CPU sec, 2.790 real sec...
[M::process] read 683354 sequences (100000071 bp) in 2.094 CPU sec, 2.097 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 283017, 5, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 214, 314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 560)
[M::mem_pestat] mean and std.dev: (212.43, 91.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 683)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 305, 427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 881)
[M::mem_pestat] mean and std.dev: (322.53, 151.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1108)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 209, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1011)
[M::mem_pestat] mean and std.dev: (225.00, 111.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1294)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683626 reads in 189.769 CPU sec, 6.019 real sec
[M::mem_process_seqs] Processed 683698 reads in 126.533 CPU sec, 4.006 real sec
sorting block 98, #reads = 1070189 mem = 536882979 peak = 998035456
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 282433, 11, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 313, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 594)
[M::mem_pestat] mean and std.dev: (275.63, 116.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 743)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 298, 422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 874)
[M::mem_pestat] mean and std.dev: (318.52, 152.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1100)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1276, 2058, 3605)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8263)
[M::mem_pestat] mean and std.dev: (2117.36, 1125.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10592)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 183, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 743)
[M::mem_pestat] mean and std.dev: (218.63, 97.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 939)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682824 sequences (100000056 bp) in 2.923 CPU sec, 3.058 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 282034, 5, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 259, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 647)
[M::mem_pestat] mean and std.dev: (233.74, 97.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 807)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 306, 429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 885)
[M::mem_pestat] mean and std.dev: (324.24, 152.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1113)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 302, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 597)
[M::mem_pestat] mean and std.dev: (246.65, 72.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 726)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 684514 sequences (100000128 bp) in 2.070 CPU sec, 2.064 real sec...
[M::mem_process_seqs] Processed 684454 reads in 185.540 CPU sec, 5.875 real sec
sorting block 99, #reads = 1072102 mem = 536879259 peak = 998035456
[M::mem_process_seqs] Processed 683354 reads in 122.152 CPU sec, 3.868 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 281576, 11, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 252, 515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1155)
[M::mem_pestat] mean and std.dev: (319.57, 153.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1475)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 312, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 897)
[M::mem_pestat] mean and std.dev: (329.25, 155.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1128)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (126, 1257, 1373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3867)
[M::mem_pestat] mean and std.dev: (802.64, 577.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5114)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 210, 244)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 414)
[M::mem_pestat] mean and std.dev: (188.57, 58.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 499)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682008 sequences (100000061 bp) in 2.838 CPU sec, 2.951 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 282527, 5, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 373, 678)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1602)
[M::mem_pestat] mean and std.dev: (415.17, 257.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2064)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 298, 424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 882)
[M::mem_pestat] mean and std.dev: (320.12, 155.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1111)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 227, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 658)
[M::mem_pestat] mean and std.dev: (272.44, 141.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 837)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682262 sequences (100000269 bp) in 2.010 CPU sec, 2.011 real sec...
[M::mem_process_seqs] Processed 682824 reads in 178.370 CPU sec, 5.647 real sec
sorting block 100, #reads = 1071933 mem = 536880472 peak = 998035456
[M::mem_process_seqs] Processed 684514 reads in 117.507 CPU sec, 3.720 real sec
sorting block 101, #reads = 1073752 mem = 536880226 peak = 998035456
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 281690, 3, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 284, 534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1176)
[M::mem_pestat] mean and std.dev: (322.81, 169.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1497)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 318, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 924)
[M::mem_pestat] mean and std.dev: (335.93, 159.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1163)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 297, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1041)
[M::mem_pestat] mean and std.dev: (299.68, 181.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1337)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682192 sequences (100000219 bp) in 2.927 CPU sec, 3.026 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281357, 5, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 256, 387)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 813)
[M::mem_pestat] mean and std.dev: (220.03, 85.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1026)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 315, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 922)
[M::mem_pestat] mean and std.dev: (335.01, 160.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1161)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 339, 884)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2218)
[M::mem_pestat] mean and std.dev: (394.00, 263.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2885)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682324 sequences (100000262 bp) in 1.979 CPU sec, 1.984 real sec...
[M::mem_process_seqs] Processed 682008 reads in 178.808 CPU sec, 5.657 real sec
[M::mem_process_seqs] Processed 682262 reads in 117.616 CPU sec, 3.716 real sec
sorting block 102, #reads = 1071496 mem = 536876732 peak = 998035456
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 280893, 14, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 186, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (218.18, 93.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 955)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 317, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 937)
[M::mem_pestat] mean and std.dev: (337.43, 163.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1181)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (333, 1012, 1254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3096)
[M::mem_pestat] mean and std.dev: (832.36, 593.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4017)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 316, 706)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1630)
[M::mem_pestat] mean and std.dev: (438.35, 279.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2092)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681762 sequences (100000175 bp) in 2.800 CPU sec, 2.906 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 281481, 6, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 312, 524)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1168)
[M::mem_pestat] mean and std.dev: (315.49, 170.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1490)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 316, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 929)
[M::mem_pestat] mean and std.dev: (336.63, 162.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1170)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 261, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 522)
[M::mem_pestat] mean and std.dev: (251.54, 94.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 633)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681302 sequences (100000234 bp) in 1.790 CPU sec, 1.786 real sec...
[M::mem_process_seqs] Processed 682192 reads in 172.454 CPU sec, 5.465 real sec
[M::mem_process_seqs] Processed 682324 reads in 110.921 CPU sec, 3.512 real sec
sorting block 103, #reads = 1072242 mem = 536879555 peak = 998035456
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 281671, 16, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 357, 689)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1613)
[M::mem_pestat] mean and std.dev: (324.23, 170.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2075)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 319, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 925)
[M::mem_pestat] mean and std.dev: (337.46, 161.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1164)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 894, 2393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6719)
[M::mem_pestat] mean and std.dev: (1846.50, 1912.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9497)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 282, 427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 797)
[M::mem_pestat] mean and std.dev: (276.71, 104.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 982)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681268 sequences (100000015 bp) in 2.822 CPU sec, 2.940 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 281120, 4, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 310, 986)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2468)
[M::mem_pestat] mean and std.dev: (360.12, 257.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3209)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 321, 451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 933)
[M::mem_pestat] mean and std.dev: (340.59, 162.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1174)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 311, 651)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1543)
[M::mem_pestat] mean and std.dev: (450.43, 357.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1989)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681714 sequences (100000247 bp) in 1.780 CPU sec, 1.779 real sec...
[M::mem_process_seqs] Processed 681762 reads in 174.095 CPU sec, 5.519 real sec
sorting block 104, #reads = 1072145 mem = 536879269 peak = 998035456
[M::mem_process_seqs] Processed 681302 reads in 116.448 CPU sec, 3.687 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 281200, 8, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (127, 300, 475)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1171)
[M::mem_pestat] mean and std.dev: (283.60, 192.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1519)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 323, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 939)
[M::mem_pestat] mean and std.dev: (341.89, 163.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1182)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 264, 625)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1387)
[M::mem_pestat] mean and std.dev: (380.86, 242.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1768)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 686260 sequences (100000109 bp) in 2.727 CPU sec, 2.845 real sec...
[M::process] read 686334 sequences (100000121 bp) in 1.530 CPU sec, 1.535 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 281266, 6, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 292, 791)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2033)
[M::mem_pestat] mean and std.dev: (495.08, 478.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2654)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 318, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 930)
[M::mem_pestat] mean and std.dev: (337.80, 161.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1171)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 219, 404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 808)
[M::mem_pestat] mean and std.dev: (281.40, 144.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1010)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681268 reads in 177.259 CPU sec, 5.631 real sec
sorting block 105, #reads = 1070912 mem = 536877310 peak = 998035456
[M::mem_process_seqs] Processed 681714 reads in 117.812 CPU sec, 3.745 real sec
sorting block 106, #reads = 1068887 mem = 536880947 peak = 998035456
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 283004, 4, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 262, 518)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1202)
[M::mem_pestat] mean and std.dev: (304.59, 214.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1544)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 290, 414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 862)
[M::mem_pestat] mean and std.dev: (312.55, 152.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1086)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 222, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 717)
[M::mem_pestat] mean and std.dev: (209.10, 75.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 902)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 685298 sequences (100000052 bp) in 2.763 CPU sec, 2.864 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 283094, 8, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 261, 649)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1637)
[M::mem_pestat] mean and std.dev: (399.07, 369.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2131)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 289, 413)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 859)
[M::mem_pestat] mean and std.dev: (311.69, 152.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1082)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 331, 520)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1208)
[M::mem_pestat] mean and std.dev: (378.19, 251.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1552)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 685074 sequences (100000181 bp) in 1.940 CPU sec, 1.938 real sec...
[M::mem_process_seqs] Processed 686260 reads in 174.723 CPU sec, 5.540 real sec
[M::mem_process_seqs] Processed 686334 reads in 108.230 CPU sec, 3.420 real sec
sorting block 107, #reads = 1066624 mem = 536879374 peak = 998035456
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 282480, 8, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (254, 296, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (76, 521)
[M::mem_pestat] mean and std.dev: (291.82, 97.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 680)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 295, 416)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 860)
[M::mem_pestat] mean and std.dev: (315.46, 151.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1082)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 304, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 929)
[M::mem_pestat] mean and std.dev: (291.06, 139.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1176)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 684256 sequences (100000197 bp) in 2.822 CPU sec, 2.926 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 282849, 10, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 490, 1098)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2894)
[M::mem_pestat] mean and std.dev: (739.52, 690.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3792)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 296, 418)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 866)
[M::mem_pestat] mean and std.dev: (316.43, 152.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1090)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (756, 756, 2362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5574)
[M::mem_pestat] mean and std.dev: (1237.80, 849.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7180)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 235, 486)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1146)
[M::mem_pestat] mean and std.dev: (289.53, 179.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1476)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683656 sequences (100000292 bp) in 1.480 CPU sec, 1.484 real sec...
[M::mem_process_seqs] Processed 685298 reads in 160.983 CPU sec, 5.109 real sec
[M::mem_process_seqs] Processed 685074 reads in 102.331 CPU sec, 3.243 real sec
sorting block 108, #reads = 1075723 mem = 536878319 peak = 998035456
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 281946, 10, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 187, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 803)
[M::mem_pestat] mean and std.dev: (245.65, 180.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1021)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 301, 421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 869)
[M::mem_pestat] mean and std.dev: (319.85, 152.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1093)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (94, 287, 985)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2767)
[M::mem_pestat] mean and std.dev: (591.90, 716.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3658)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 331, 568)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1306)
[M::mem_pestat] mean and std.dev: (325.80, 187.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1675)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683690 sequences (100000181 bp) in 2.857 CPU sec, 2.966 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 281732, 5, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 241, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (271.21, 132.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 305, 426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 878)
[M::mem_pestat] mean and std.dev: (323.21, 153.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1104)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 254, 417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 887)
[M::mem_pestat] mean and std.dev: (281.48, 144.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1122)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684256 reads in 157.654 CPU sec, 4.990 real sec
[M::process] read 683426 sequences (100000151 bp) in 2.053 CPU sec, 2.067 real sec...
sorting block 109, #reads = 1076838 mem = 536878615 peak = 998035456
[M::mem_process_seqs] Processed 683656 reads in 102.623 CPU sec, 3.231 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 282473, 9, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 206, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (235.25, 132.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 826)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 307, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 896)
[M::mem_pestat] mean and std.dev: (326.30, 156.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1128)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 224, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 587)
[M::mem_pestat] mean and std.dev: (257.12, 95.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 722)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 110, #reads = 1076028 mem = 536878107 peak = 998035456
[M::process] read 683234 sequences (100000074 bp) in 2.707 CPU sec, 2.824 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 282041, 9, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 179, 420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 946)
[M::mem_pestat] mean and std.dev: (221.84, 104.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1209)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 308, 433)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 897)
[M::mem_pestat] mean and std.dev: (327.20, 156.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1129)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 197, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 731)
[M::mem_pestat] mean and std.dev: (218.93, 93.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 919)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683690 reads in 160.841 CPU sec, 5.105 real sec
[M::process] read 683102 sequences (100000086 bp) in 2.104 CPU sec, 2.120 real sec...
[M::mem_process_seqs] Processed 683426 reads in 105.892 CPU sec, 3.327 real sec
sorting block 111, #reads = 1075842 mem = 536876967 peak = 998035456
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 281846, 4, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 246, 641)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1561)
[M::mem_pestat] mean and std.dev: (379.22, 282.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2021)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 311, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 904)
[M::mem_pestat] mean and std.dev: (329.33, 157.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1138)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 280, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (279.12, 162.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 931)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683128 sequences (100000239 bp) in 2.771 CPU sec, 2.885 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 282397, 7, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 217, 287)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 537)
[M::mem_pestat] mean and std.dev: (216.32, 86.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 662)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 309, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 889)
[M::mem_pestat] mean and std.dev: (327.00, 155.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1118)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 233, 789)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2055)
[M::mem_pestat] mean and std.dev: (467.75, 539.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2688)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683306 sequences (100000251 bp) in 1.520 CPU sec, 1.518 real sec...
[M::mem_process_seqs] Processed 683234 reads in 160.421 CPU sec, 5.096 real sec
[M::mem_process_seqs] Processed 683102 reads in 105.196 CPU sec, 3.327 real sec
sorting block 112, #reads = 1076485 mem = 536880081 peak = 998035456
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 282193, 9, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 315, 477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1081)
[M::mem_pestat] mean and std.dev: (334.04, 214.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1383)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 309, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 892)
[M::mem_pestat] mean and std.dev: (327.52, 155.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1122)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 240, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701)
[M::mem_pestat] mean and std.dev: (207.91, 82.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 880)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682640 sequences (100000192 bp) in 3.040 CPU sec, 3.156 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 282250, 5, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 241, 285)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 503)
[M::mem_pestat] mean and std.dev: (189.79, 63.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 612)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 308, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 889)
[M::mem_pestat] mean and std.dev: (326.39, 155.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1118)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 238, 394)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 780)
[M::mem_pestat] mean and std.dev: (265.94, 117.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 973)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683128 reads in 164.679 CPU sec, 5.216 real sec
[M::process] read 682158 sequences (100000144 bp) in 2.012 CPU sec, 2.038 real sec...
[M::mem_process_seqs] Processed 683306 reads in 106.585 CPU sec, 3.360 real sec
sorting block 113, #reads = 1074992 mem = 536879332 peak = 998035456
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 281147, 12, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 312, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 722)
[M::mem_pestat] mean and std.dev: (307.24, 146.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 897)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 312, 434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 894)
[M::mem_pestat] mean and std.dev: (329.41, 155.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1124)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (55, 245, 1583)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4639)
[M::mem_pestat] mean and std.dev: (313.80, 456.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6167)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 244, 535)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1249)
[M::mem_pestat] mean and std.dev: (288.31, 185.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1606)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682044 sequences (100000124 bp) in 2.565 CPU sec, 2.709 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 281647, 4, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 323, 808)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2126)
[M::mem_pestat] mean and std.dev: (385.96, 294.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2785)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 312, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 884)
[M::mem_pestat] mean and std.dev: (329.31, 154.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1110)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 326, 1016)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2598)
[M::mem_pestat] mean and std.dev: (542.39, 545.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3389)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682132 sequences (100000029 bp) in 1.540 CPU sec, 1.538 real sec...
[M::mem_process_seqs] Processed 682640 reads in 164.983 CPU sec, 5.246 real sec
sorting block 114, #reads = 1074065 mem = 536878143 peak = 998035456
[M::mem_process_seqs] Processed 682158 reads in 106.027 CPU sec, 3.366 real sec
sorting block 115, #reads = 1073651 mem = 536883574 peak = 998035456
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 281670, 7, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 211, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (211.54, 124.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 874)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 315, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 903)
[M::mem_pestat] mean and std.dev: (333.03, 157.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1135)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 347, 524)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1138)
[M::mem_pestat] mean and std.dev: (355.66, 210.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1445)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681992 sequences (100000047 bp) in 2.938 CPU sec, 3.055 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 281699, 13, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 299, 712)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1706)
[M::mem_pestat] mean and std.dev: (303.05, 206.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2203)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 315, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 908)
[M::mem_pestat] mean and std.dev: (333.53, 158.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1142)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1408, 1408, 1967)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (290, 3085)
[M::mem_pestat] mean and std.dev: (1613.54, 281.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3644)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 192, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 611)
[M::mem_pestat] mean and std.dev: (212.06, 100.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 764)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682044 reads in 166.829 CPU sec, 5.280 real sec
[M::process] read 681754 sequences (100000061 bp) in 1.949 CPU sec, 1.947 real sec...
[M::mem_process_seqs] Processed 682132 reads in 108.970 CPU sec, 3.441 real sec
sorting block 116, #reads = 1074540 mem = 536880646 peak = 998035456
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 280862, 12, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 283, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 597)
[M::mem_pestat] mean and std.dev: (225.88, 71.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 735)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 316, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 909)
[M::mem_pestat] mean and std.dev: (333.91, 158.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1143)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (26, 301, 879)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2585)
[M::mem_pestat] mean and std.dev: (533.58, 811.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3781)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 323, 1080)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2854)
[M::mem_pestat] mean and std.dev: (542.15, 575.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3741)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682064 sequences (100000223 bp) in 3.068 CPU sec, 3.184 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 280713, 9, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 298, 1599)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4517)
[M::mem_pestat] mean and std.dev: (923.55, 1201.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5976)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 316, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 909)
[M::mem_pestat] mean and std.dev: (334.67, 158.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1143)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 289, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 910)
[M::mem_pestat] mean and std.dev: (319.04, 141.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1143)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681992 reads in 170.919 CPU sec, 5.415 real sec
[M::process] read 681568 sequences (100000153 bp) in 1.978 CPU sec, 1.988 real sec...
[M::mem_process_seqs] Processed 681754 reads in 114.167 CPU sec, 3.601 real sec
sorting block 117, #reads = 1073359 mem = 536879924 peak = 998035456
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 281375, 6, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (285, 347, 488)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 894)
[M::mem_pestat] mean and std.dev: (414.16, 209.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1250)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 314, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 908)
[M::mem_pestat] mean and std.dev: (333.06, 158.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1142)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 293, 434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 914)
[M::mem_pestat] mean and std.dev: (321.97, 172.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1154)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681836 sequences (100000083 bp) in 2.742 CPU sec, 2.853 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 281687, 7, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 252, 423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 927)
[M::mem_pestat] mean and std.dev: (269.89, 128.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1179)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 316, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 912)
[M::mem_pestat] mean and std.dev: (334.66, 158.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1147)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 270, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 649)
[M::mem_pestat] mean and std.dev: (247.52, 58.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 791)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681942 sequences (100000088 bp) in 2.009 CPU sec, 2.012 real sec...
[M::mem_process_seqs] Processed 682064 reads in 172.205 CPU sec, 5.449 real sec
sorting block 118, #reads = 1073068 mem = 536882643 peak = 998035456
[M::mem_process_seqs] Processed 681568 reads in 111.048 CPU sec, 3.511 real sec
sorting block 119, #reads = 1073886 mem = 536884259 peak = 998035456
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 281145, 5, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 231, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 681)
[M::mem_pestat] mean and std.dev: (230.92, 114.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 852)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 314, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 911)
[M::mem_pestat] mean and std.dev: (333.63, 158.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1146)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 243, 576)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1380)
[M::mem_pestat] mean and std.dev: (330.52, 245.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1782)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682118 sequences (100000131 bp) in 3.000 CPU sec, 3.117 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 281143, 11, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 328, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1048)
[M::mem_pestat] mean and std.dev: (317.12, 153.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1338)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 314, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 911)
[M::mem_pestat] mean and std.dev: (334.02, 159.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1146)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 2518, 2621)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7383)
[M::mem_pestat] mean and std.dev: (1594.91, 1353.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9764)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 352, 560)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1306)
[M::mem_pestat] mean and std.dev: (304.41, 139.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1679)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681890 sequences (100000153 bp) in 1.960 CPU sec, 1.960 real sec...
[M::mem_process_seqs] Processed 681836 reads in 173.674 CPU sec, 5.493 real sec
[M::mem_process_seqs] Processed 681942 reads in 112.039 CPU sec, 3.533 real sec
sorting block 120, #reads = 1072587 mem = 536876893 peak = 998035456
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 281098, 3, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 271, 660)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1590)
[M::mem_pestat] mean and std.dev: (388.36, 304.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2055)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 314, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 911)
[M::mem_pestat] mean and std.dev: (333.67, 159.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1146)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 280, 451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1007)
[M::mem_pestat] mean and std.dev: (322.11, 177.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1285)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682268 sequences (100000186 bp) in 3.029 CPU sec, 3.122 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 281401, 13, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 245, 311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 635)
[M::mem_pestat] mean and std.dev: (237.84, 94.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 797)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 315, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 920)
[M::mem_pestat] mean and std.dev: (335.26, 161.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1158)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 536, 1967)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5587)
[M::mem_pestat] mean and std.dev: (919.92, 940.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7397)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 250, 484)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1084)
[M::mem_pestat] mean and std.dev: (279.27, 154.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1384)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682118 reads in 168.994 CPU sec, 5.346 real sec
[M::process] read 681980 sequences (100000086 bp) in 2.028 CPU sec, 2.034 real sec...
[M::mem_process_seqs] Processed 681890 reads in 111.077 CPU sec, 3.501 real sec
sorting block 121, #reads = 1072519 mem = 536880106 peak = 998035456
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 281792, 8, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 260, 388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 828)
[M::mem_pestat] mean and std.dev: (274.96, 136.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1048)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 312, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 915)
[M::mem_pestat] mean and std.dev: (333.26, 161.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1152)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 289, 533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1245)
[M::mem_pestat] mean and std.dev: (355.63, 256.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1601)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681606 sequences (100000200 bp) in 3.170 CPU sec, 3.311 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 281609, 13, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 227, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 808)
[M::mem_pestat] mean and std.dev: (255.98, 128.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1031)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 313, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 902)
[M::mem_pestat] mean and std.dev: (332.29, 158.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1134)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (663, 2213, 6527)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 18255)
[M::mem_pestat] mean and std.dev: (2880.85, 2617.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 24119)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 451, 929)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2273)
[M::mem_pestat] mean and std.dev: (587.81, 452.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2945)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682268 reads in 167.525 CPU sec, 5.305 real sec
[M::process] read 688338 sequences (100000200 bp) in 2.010 CPU sec, 2.030 real sec...
[M::mem_process_seqs] Processed 681980 reads in 112.692 CPU sec, 3.551 real sec
sorting block 122, #reads = 1071274 mem = 536880126 peak = 998035456
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 280822, 2, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 224, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1114)
[M::mem_pestat] mean and std.dev: (327.17, 254.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1435)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 316, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 921)
[M::mem_pestat] mean and std.dev: (336.71, 161.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1159)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 259, 519)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1183)
[M::mem_pestat] mean and std.dev: (313.66, 188.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1515)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 689690 sequences (100000144 bp) in 2.749 CPU sec, 2.838 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 283636, 4, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 224, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1058)
[M::mem_pestat] mean and std.dev: (212.48, 114.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1366)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 279, 402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 838)
[M::mem_pestat] mean and std.dev: (303.48, 149.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1056)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 254, 311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 589)
[M::mem_pestat] mean and std.dev: (231.92, 73.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 728)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 688076 sequences (100000272 bp) in 2.070 CPU sec, 2.068 real sec...
[M::mem_process_seqs] Processed 681606 reads in 186.138 CPU sec, 5.899 real sec
sorting block 123, #reads = 1071198 mem = 536875254 peak = 998035456
[M::mem_process_seqs] Processed 688338 reads in 126.074 CPU sec, 3.987 real sec
sorting block 124, #reads = 1062838 mem = 536880383 peak = 998035456
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 284384, 7, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 247, 664)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1668)
[M::mem_pestat] mean and std.dev: (345.72, 339.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2170)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 272, 392)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 816)
[M::mem_pestat] mean and std.dev: (295.91, 144.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1028)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 227, 405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 873)
[M::mem_pestat] mean and std.dev: (249.24, 117.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1107)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 686844 sequences (100000067 bp) in 3.043 CPU sec, 3.161 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 283166, 7, 20)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 358, 711)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1739)
[M::mem_pestat] mean and std.dev: (363.47, 213.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2253)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 281, 401)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 833)
[M::mem_pestat] mean and std.dev: (302.70, 146.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1049)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 179, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 745)
[M::mem_pestat] mean and std.dev: (217.44, 104.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 946)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 685878 sequences (100000037 bp) in 2.010 CPU sec, 2.005 real sec...
[M::mem_process_seqs] Processed 689690 reads in 179.979 CPU sec, 5.688 real sec
[M::mem_process_seqs] Processed 688076 reads in 111.900 CPU sec, 3.539 real sec
sorting block 125, #reads = 1071272 mem = 536876389 peak = 998035456
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 283258, 8, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 257, 665)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1683)
[M::mem_pestat] mean and std.dev: (331.19, 228.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2192)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 286, 405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 839)
[M::mem_pestat] mean and std.dev: (305.73, 145.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1056)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 323, 538)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1134)
[M::mem_pestat] mean and std.dev: (334.83, 178.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1432)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 685410 sequences (100000058 bp) in 2.538 CPU sec, 2.654 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 283384, 13, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 186, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 665)
[M::mem_pestat] mean and std.dev: (210.69, 82.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 837)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 290, 406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 834)
[M::mem_pestat] mean and std.dev: (308.38, 144.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1048)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1019, 1720, 2197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4553)
[M::mem_pestat] mean and std.dev: (1501.33, 749.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5731)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 343, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 869)
[M::mem_pestat] mean and std.dev: (298.92, 120.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1084)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 685476 sequences (100000224 bp) in 1.970 CPU sec, 1.971 real sec...
[M::mem_process_seqs] Processed 686844 reads in 170.056 CPU sec, 5.394 real sec
[M::mem_process_seqs] Processed 685878 reads in 107.659 CPU sec, 3.404 real sec
sorting block 126, #reads = 1070573 mem = 536881162 peak = 998035456
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 282714, 5, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 273, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 746)
[M::mem_pestat] mean and std.dev: (247.46, 108.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 940)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 294, 415)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 859)
[M::mem_pestat] mean and std.dev: (313.20, 148.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1081)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 246, 657)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1643)
[M::mem_pestat] mean and std.dev: (398.05, 380.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2136)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 684924 sequences (100000295 bp) in 2.496 CPU sec, 2.597 real sec...
[M::process] read 684062 sequences (100000027 bp) in 1.590 CPU sec, 1.596 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 282586, 7, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 364, 629)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1551)
[M::mem_pestat] mean and std.dev: (330.65, 192.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2012)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 295, 419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 871)
[M::mem_pestat] mean and std.dev: (315.26, 151.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1097)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (268, 545, 2083)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5713)
[M::mem_pestat] mean and std.dev: (1206.86, 1465.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7528)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 685410 reads in 176.914 CPU sec, 5.627 real sec
sorting block 127, #reads = 1070821 mem = 536880140 peak = 998035456
[M::mem_process_seqs] Processed 685476 reads in 112.432 CPU sec, 3.571 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 283182, 6, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 311, 378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 712)
[M::mem_pestat] mean and std.dev: (306.00, 120.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 299, 422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 876)
[M::mem_pestat] mean and std.dev: (318.36, 152.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1103)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 245, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 672)
[M::mem_pestat] mean and std.dev: (267.82, 97.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 831)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 128, #reads = 1070152 mem = 536879643 peak = 998035456
[M::process] read 684172 sequences (100000243 bp) in 2.739 CPU sec, 2.857 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 281949, 10, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 284, 434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 934)
[M::mem_pestat] mean and std.dev: (286.00, 149.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1184)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 302, 428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 888)
[M::mem_pestat] mean and std.dev: (321.68, 153.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1118)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (68, 68, 68)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (68, 68)
[M::mem_pestat] mean and std.dev: (68.00, 0.00)
[M::mem_pestat] low and high boundaries for proper pairs: (68, 68)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 224, 283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 479)
[M::mem_pestat] mean and std.dev: (210.25, 65.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 577)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 684262 sequences (100000080 bp) in 2.000 CPU sec, 1.993 real sec...
[M::mem_process_seqs] Processed 684924 reads in 175.822 CPU sec, 5.571 real sec
[M::mem_process_seqs] Processed 684062 reads in 114.907 CPU sec, 3.633 real sec
sorting block 129, #reads = 1072706 mem = 536881604 peak = 998035456
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 282609, 8, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 258, 1149)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3021)
[M::mem_pestat] mean and std.dev: (544.42, 563.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3957)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 303, 427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 885)
[M::mem_pestat] mean and std.dev: (322.14, 153.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1114)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 231, 483)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1067)
[M::mem_pestat] mean and std.dev: (316.75, 218.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1359)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683272 sequences (100000195 bp) in 2.999 CPU sec, 3.099 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 282566, 8, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (132, 223, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 810)
[M::mem_pestat] mean and std.dev: (245.28, 150.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1036)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 299, 420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 866)
[M::mem_pestat] mean and std.dev: (317.54, 149.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1089)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 231, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1102)
[M::mem_pestat] mean and std.dev: (277.71, 182.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1419)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681944 sequences (100000100 bp) in 1.900 CPU sec, 1.910 real sec...
[M::mem_process_seqs] Processed 684172 reads in 176.635 CPU sec, 5.593 real sec
[M::mem_process_seqs] Processed 684262 reads in 116.695 CPU sec, 3.689 real sec
sorting block 130, #reads = 1070831 mem = 536876970 peak = 998035456
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 282002, 15, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 261, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1009)
[M::mem_pestat] mean and std.dev: (278.64, 154.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1289)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 306, 428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 882)
[M::mem_pestat] mean and std.dev: (323.82, 152.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1109)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (603, 1905, 2434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6096)
[M::mem_pestat] mean and std.dev: (1713.40, 1044.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7927)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 266, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 749)
[M::mem_pestat] mean and std.dev: (259.72, 108.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 940)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682996 sequences (100000052 bp) in 2.994 CPU sec, 3.106 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 281983, 12, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 218, 1208)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3328)
[M::mem_pestat] mean and std.dev: (604.08, 702.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4388)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 315, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 891)
[M::mem_pestat] mean and std.dev: (330.88, 153.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1119)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (20, 508, 1674)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4982)
[M::mem_pestat] mean and std.dev: (744.75, 753.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6636)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 233, 565)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1323)
[M::mem_pestat] mean and std.dev: (357.45, 272.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1702)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683178 sequences (100000166 bp) in 2.020 CPU sec, 2.015 real sec...
[M::mem_process_seqs] Processed 683272 reads in 173.935 CPU sec, 5.501 real sec
sorting block 131, #reads = 1069869 mem = 536883902 peak = 998035456
[M::mem_process_seqs] Processed 681944 reads in 111.985 CPU sec, 3.539 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 281827, 12, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 301, 423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 903)
[M::mem_pestat] mean and std.dev: (324.28, 160.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1143)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 308, 428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 880)
[M::mem_pestat] mean and std.dev: (324.83, 152.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1106)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (108, 187, 2656)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7752)
[M::mem_pestat] mean and std.dev: (1096.17, 1673.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10300)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 489, 973)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2411)
[M::mem_pestat] mean and std.dev: (633.16, 512.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3130)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682714 sequences (100000177 bp) in 2.822 CPU sec, 2.914 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 281628, 11, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 190, 415)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 925)
[M::mem_pestat] mean and std.dev: (268.18, 182.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1180)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 305, 428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 882)
[M::mem_pestat] mean and std.dev: (324.06, 152.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1109)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (341, 1046, 2595)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7103)
[M::mem_pestat] mean and std.dev: (1306.00, 1100.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9357)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 256, 540)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1232)
[M::mem_pestat] mean and std.dev: (328.93, 218.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1578)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682510 sequences (100000171 bp) in 1.940 CPU sec, 1.944 real sec...
[M::mem_process_seqs] Processed 682996 reads in 175.112 CPU sec, 5.547 real sec
sorting block 132, #reads = 1070955 mem = 536880384 peak = 998035456
[M::mem_process_seqs] Processed 683178 reads in 114.039 CPU sec, 3.608 real sec
sorting block 133, #reads = 1070646 mem = 536878861 peak = 998035456
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281160, 10, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 204, 551)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1333)
[M::mem_pestat] mean and std.dev: (273.51, 176.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1724)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 306, 429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 881)
[M::mem_pestat] mean and std.dev: (325.04, 152.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1107)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (507, 818, 818)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1440)
[M::mem_pestat] mean and std.dev: (693.11, 200.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1751)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 255, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1053)
[M::mem_pestat] mean and std.dev: (352.44, 245.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1346)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682700 sequences (100000090 bp) in 2.586 CPU sec, 2.696 real sec...
[M::process] read 682632 sequences (100000107 bp) in 1.530 CPU sec, 1.527 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 281419, 8, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (254, 371, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 887)
[M::mem_pestat] mean and std.dev: (328.36, 119.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1098)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 308, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 882)
[M::mem_pestat] mean and std.dev: (326.42, 153.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1108)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 349, 1192)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3148)
[M::mem_pestat] mean and std.dev: (476.29, 457.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4126)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682714 reads in 167.757 CPU sec, 5.330 real sec
[M::mem_process_seqs] Processed 682510 reads in 109.003 CPU sec, 3.460 real sec
sorting block 134, #reads = 1070331 mem = 536888942 peak = 998035456
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 281190, 9, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 202, 395)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 819)
[M::mem_pestat] mean and std.dev: (260.28, 122.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1031)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 309, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 888)
[M::mem_pestat] mean and std.dev: (327.33, 154.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1116)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 270, 403)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 917)
[M::mem_pestat] mean and std.dev: (269.28, 179.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1174)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682620 sequences (100000186 bp) in 2.972 CPU sec, 3.067 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281470, 19, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 263, 667)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1627)
[M::mem_pestat] mean and std.dev: (430.37, 341.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2107)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 308, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 887)
[M::mem_pestat] mean and std.dev: (327.30, 155.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1115)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (455, 569, 875)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1715)
[M::mem_pestat] mean and std.dev: (498.60, 139.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2135)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (273, 377, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 768)
[M::mem_pestat] mean and std.dev: (341.86, 126.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 933)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682210 sequences (100000213 bp) in 1.930 CPU sec, 1.929 real sec...
[M::mem_process_seqs] Processed 682700 reads in 170.266 CPU sec, 5.388 real sec
[M::mem_process_seqs] Processed 682632 reads in 111.470 CPU sec, 3.516 real sec
sorting block 135, #reads = 1072575 mem = 536879223 peak = 998035456
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 280976, 8, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 251, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 658)
[M::mem_pestat] mean and std.dev: (231.97, 87.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 823)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 310, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 902)
[M::mem_pestat] mean and std.dev: (329.53, 157.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1135)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 435, 642)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1538)
[M::mem_pestat] mean and std.dev: (478.75, 350.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1986)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682494 sequences (100000085 bp) in 2.878 CPU sec, 2.974 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 281406, 11, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 372, 741)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1831)
[M::mem_pestat] mean and std.dev: (396.10, 327.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2376)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 311, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 901)
[M::mem_pestat] mean and std.dev: (330.96, 157.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1133)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (938, 938, 2637)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6035)
[M::mem_pestat] mean and std.dev: (1375.18, 838.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7734)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 305, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1104)
[M::mem_pestat] mean and std.dev: (322.68, 193.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1420)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682620 reads in 168.671 CPU sec, 5.361 real sec
[M::process] read 681924 sequences (100000281 bp) in 2.155 CPU sec, 2.175 real sec...
[M::mem_process_seqs] Processed 682210 reads in 111.444 CPU sec, 3.506 real sec
sorting block 136, #reads = 1072021 mem = 536883184 peak = 998035456
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 281107, 7, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 282, 451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 971)
[M::mem_pestat] mean and std.dev: (321.34, 165.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1231)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 309, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 900)
[M::mem_pestat] mean and std.dev: (330.15, 157.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1132)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 264, 387)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 797)
[M::mem_pestat] mean and std.dev: (277.80, 148.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1002)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 137, #reads = 1072529 mem = 536878293 peak = 998035456
[M::process] read 680524 sequences (100000199 bp) in 2.486 CPU sec, 2.594 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281041, 6, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 296, 570)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1348)
[M::mem_pestat] mean and std.dev: (395.33, 269.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1737)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 313, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 910)
[M::mem_pestat] mean and std.dev: (333.02, 158.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1145)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (297, 326, 629)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1293)
[M::mem_pestat] mean and std.dev: (409.26, 261.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1625)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681664 sequences (100000109 bp) in 1.470 CPU sec, 1.466 real sec...
[M::mem_process_seqs] Processed 682494 reads in 166.590 CPU sec, 5.306 real sec
[M::mem_process_seqs] Processed 681924 reads in 111.878 CPU sec, 3.548 real sec
sorting block 138, #reads = 1072437 mem = 536879450 peak = 998035456
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 281082, 7, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 188, 278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 558)
[M::mem_pestat] mean and std.dev: (186.85, 63.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 698)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 325, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 935)
[M::mem_pestat] mean and std.dev: (343.12, 162.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1176)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 278, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 973)
[M::mem_pestat] mean and std.dev: (339.64, 246.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1324)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 453700 sequences (66496116 bp) in 2.430 CPU sec, 2.528 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 281353, 12, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 273, 314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 648)
[M::mem_pestat] mean and std.dev: (242.24, 115.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 815)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 315, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 912)
[M::mem_pestat] mean and std.dev: (335.03, 159.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1147)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1297, 1409, 2315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4351)
[M::mem_pestat] mean and std.dev: (1252.18, 873.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5369)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (319, 346, 585)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1117)
[M::mem_pestat] mean and std.dev: (353.07, 140.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1383)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680524 reads in 162.681 CPU sec, 5.223 real sec
[M::mem_process_seqs] Processed 681664 reads in 105.124 CPU sec, 3.392 real sec
sorting block 139, #reads = 1071898 mem = 536877569 peak = 998035456
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 187284, 4, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 218, 569)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1433)
[M::mem_pestat] mean and std.dev: (315.32, 290.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1865)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 313, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 904)
[M::mem_pestat] mean and std.dev: (332.21, 158.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1137)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 255, 525)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1087)
[M::mem_pestat] mean and std.dev: (338.32, 203.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1368)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 453700 reads in 64.628 CPU sec, 2.136 real sec
sorting block 140, #reads = 1072310 mem = 536886673 peak = 998035456
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 150612752
overall: 69695455232 mem 23329.526 user 868.953 sys 796.729 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1136_4XR-T1-TDNA-1_A23MHWWLT4_1.L007\tPU:L007\tSM:1136_4XR-T1-TDNA-1_A23MHWWLT4_1\tLB:1136_4XR-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1136_4XR-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1136_4XR-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 796.758 sec; CPU: 24198.482 sec
sorting block 141, #reads = 45912 mem = 23189141 peak = 998035456
uniq header count 1
merging 142 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31 max 384
algo: util-sort
license: sentieon:util=1
output file size: 8300171280
output reads: 151522724
bam_mem_sort: 142 calls 89.415 user 1.609 sys 91.214 real
bam_write: 142 calls 46.037 user 3.379 sys 52.593 real
execute: 1 calls 45.331 user 2.396 sys 850.613 real
merge_files: 1 calls 45.279 user 2.377 sys 53.821 real
parse_chunk: 2257 calls 104.083 user 27.062 sys 133.636 real
read_chunk: 6089 calls 60.620 user 45.554 sys 708.534 real
sort_block: 1 calls 44.891 user 44.534 sys 684.026 real
write_chunk: 3830 calls 44.936 user 2.017 sys 52.834 real
overall: 3143577600 mem 2155.531 user 98.426 sys 850.631 real
ls: cannot access '*.cram': No such file or directory