This software is licensed to bgold@natera.com by Sentieon Inc.
cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1136_76X-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 2533.695 CPU sec, 106.436 real sec
[M::process] read 703824 sequences (100000081 bp) in 1.040 CPU sec, 1.051 real sec...
[M::process] read 702900 sequences (100000013 bp) in 1.640 CPU sec, 1.674 real sec...
[M::process] read 702624 sequences (100000231 bp) in 1.488 CPU sec, 1.512 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 281037, 30, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 349, 1158)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3102)
[M::mem_pestat] mean and std.dev: (498.18, 452.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4074)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (251.43, 124.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 1192, 2294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6428)
[M::mem_pestat] mean and std.dev: (1214.31, 1106.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8495)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 385, 1044)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2692)
[M::mem_pestat] mean and std.dev: (444.15, 367.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3516)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701732 sequences (100000132 bp) in 1.542 CPU sec, 1.584 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 280537, 21, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 548, 1402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3884)
[M::mem_pestat] mean and std.dev: (845.81, 980.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5125)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 232, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (255.39, 125.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 872)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (253, 731, 1738)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4708)
[M::mem_pestat] mean and std.dev: (978.48, 826.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6193)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 741, 1996)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5546)
[M::mem_pestat] mean and std.dev: (872.85, 848.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7321)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 281085, 25, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 287, 1009)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2665)
[M::mem_pestat] mean and std.dev: (508.58, 478.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3493)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 231, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (253.91, 125.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 873, 1356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3600)
[M::mem_pestat] mean and std.dev: (907.38, 776.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4722)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 317, 925)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2345)
[M::mem_pestat] mean and std.dev: (451.17, 391.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3055)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703824 reads in 308.497 CPU sec, 9.995 real sec
[M::mem_process_seqs] Processed 702624 reads in 223.528 CPU sec, 7.298 real sec
[M::mem_process_seqs] Processed 702900 reads in 250.132 CPU sec, 8.148 real sec
sorting block 0, #reads = 1070004 mem = 536879157 peak = 593584128
[M::process] read 701026 sequences (100000014 bp) in 2.354 CPU sec, 2.480 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 280976, 31, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 420, 2249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6291)
[M::mem_pestat] mean and std.dev: (1149.56, 1468.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8312)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 234, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 694)
[M::mem_pestat] mean and std.dev: (257.01, 126.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 873)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (101, 374, 990)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2768)
[M::mem_pestat] mean and std.dev: (627.34, 819.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3903)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 348, 884)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2154)
[M::mem_pestat] mean and std.dev: (533.65, 417.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2789)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700364 sequences (100000215 bp) in 1.938 CPU sec, 1.957 real sec...
[M::process] read 699770 sequences (100000088 bp) in 1.479 CPU sec, 1.483 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 280654, 23, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 326, 1391)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3741)
[M::mem_pestat] mean and std.dev: (820.02, 973.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4916)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701)
[M::mem_pestat] mean and std.dev: (258.42, 127.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 882)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (283, 1061, 1224)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3106)
[M::mem_pestat] mean and std.dev: (721.81, 496.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4047)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 438, 2093)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5853)
[M::mem_pestat] mean and std.dev: (1022.95, 1169.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7733)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701732 reads in 206.051 CPU sec, 6.552 real sec
sorting block 1, #reads = 1071085 mem = 536878387 peak = 889282560
[M::mem_process_seqs] Processed 701026 reads in 138.541 CPU sec, 4.677 real sec
sorting block 2, #reads = 1071557 mem = 536884646 peak = 889282560
[M::process] read 699114 sequences (100000007 bp) in 2.415 CPU sec, 2.494 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 280294, 15, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 389, 1107)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2953)
[M::mem_pestat] mean and std.dev: (569.24, 539.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3876)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 237, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 703)
[M::mem_pestat] mean and std.dev: (260.50, 128.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 884)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (76, 452, 1037)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2959)
[M::mem_pestat] mean and std.dev: (651.50, 706.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3920)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 434, 1471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3959)
[M::mem_pestat] mean and std.dev: (807.81, 842.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5203)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699054 sequences (100000165 bp) in 1.901 CPU sec, 1.906 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 280149, 27, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 328, 1124)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2908)
[M::mem_pestat] mean and std.dev: (637.74, 671.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3800)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 238, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709)
[M::mem_pestat] mean and std.dev: (261.69, 129.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 892)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (277, 695, 1887)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5107)
[M::mem_pestat] mean and std.dev: (929.17, 968.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6717)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (261, 335, 759)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1755)
[M::mem_pestat] mean and std.dev: (463.74, 313.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2253)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700364 reads in 208.321 CPU sec, 6.878 real sec
[M::mem_process_seqs] Processed 699770 reads in 231.357 CPU sec, 7.718 real sec
sorting block 3, #reads = 1069207 mem = 536880280 peak = 889282560
[M::process] read 699220 sequences (100000015 bp) in 2.351 CPU sec, 2.500 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 279973, 26, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 297, 1621)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4463)
[M::mem_pestat] mean and std.dev: (751.14, 826.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5884)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 241, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 720)
[M::mem_pestat] mean and std.dev: (264.47, 130.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 906)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (374, 826, 2083)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5501)
[M::mem_pestat] mean and std.dev: (1324.23, 1159.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7210)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 406, 1077)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2829)
[M::mem_pestat] mean and std.dev: (556.29, 519.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3705)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699204 sequences (100000163 bp) in 1.690 CPU sec, 1.686 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 279415, 45, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 353, 1575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4315)
[M::mem_pestat] mean and std.dev: (814.66, 923.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5685)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 240, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 716)
[M::mem_pestat] mean and std.dev: (263.60, 129.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 901)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (476, 704, 956)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1916)
[M::mem_pestat] mean and std.dev: (590.87, 353.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2396)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (321, 483, 1098)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2652)
[M::mem_pestat] mean and std.dev: (615.81, 467.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3429)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 279496, 23, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 308, 797)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1951)
[M::mem_pestat] mean and std.dev: (435.30, 342.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2528)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 240, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 719)
[M::mem_pestat] mean and std.dev: (263.75, 129.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 905)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (334, 689, 2465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6727)
[M::mem_pestat] mean and std.dev: (1211.75, 1210.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8858)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 378, 870)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2146)
[M::mem_pestat] mean and std.dev: (412.78, 363.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2784)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699114 reads in 295.706 CPU sec, 9.549 real sec
sorting block 4, #reads = 1067959 mem = 536882470 peak = 889282560
[M::mem_process_seqs] Processed 699054 reads in 226.314 CPU sec, 7.278 real sec
[M::mem_process_seqs] Processed 699220 reads in 253.536 CPU sec, 8.177 real sec
sorting block 5, #reads = 1068506 mem = 536879202 peak = 889282560
[M::process] read 699626 sequences (100000148 bp) in 2.517 CPU sec, 2.655 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 279977, 32, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 294, 884)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2294)
[M::mem_pestat] mean and std.dev: (440.31, 422.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2999)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 240, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 714)
[M::mem_pestat] mean and std.dev: (263.71, 129.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 898)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (285, 853, 1730)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4620)
[M::mem_pestat] mean and std.dev: (986.10, 1022.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6065)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 241, 412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 896)
[M::mem_pestat] mean and std.dev: (296.85, 187.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1138)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698870 sequences (100000029 bp) in 2.308 CPU sec, 2.387 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 279609, 28, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 331, 893)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2249)
[M::mem_pestat] mean and std.dev: (603.37, 583.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2937)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 239, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 707)
[M::mem_pestat] mean and std.dev: (261.70, 128.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 889)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (334, 497, 878)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1966)
[M::mem_pestat] mean and std.dev: (536.88, 302.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2510)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 439, 1138)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3002)
[M::mem_pestat] mean and std.dev: (703.90, 744.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3934)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698704 sequences (100000031 bp) in 1.859 CPU sec, 1.859 real sec...
[M::mem_process_seqs] Processed 699204 reads in 210.807 CPU sec, 6.706 real sec
sorting block 6, #reads = 1068034 mem = 536882920 peak = 889282560
[M::mem_process_seqs] Processed 699626 reads in 141.086 CPU sec, 4.576 real sec
[M::process] read 697954 sequences (100000007 bp) in 2.410 CPU sec, 2.563 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 279853, 22, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 746, 2392)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6730)
[M::mem_pestat] mean and std.dev: (1149.45, 1070.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8899)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 241, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 714)
[M::mem_pestat] mean and std.dev: (264.28, 130.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 898)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 635, 2710)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7804)
[M::mem_pestat] mean and std.dev: (903.80, 1048.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10351)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 454, 1761)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4817)
[M::mem_pestat] mean and std.dev: (936.57, 963.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6345)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698438 sequences (100000256 bp) in 1.726 CPU sec, 1.735 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 279221, 19, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 287, 536)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1312)
[M::mem_pestat] mean and std.dev: (336.14, 273.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1700)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 242, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 712)
[M::mem_pestat] mean and std.dev: (264.68, 129.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 895)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (383, 868, 4323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12203)
[M::mem_pestat] mean and std.dev: (1778.74, 2044.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16143)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (286, 481, 1316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3376)
[M::mem_pestat] mean and std.dev: (826.93, 715.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4406)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 279317, 29, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 419, 1549)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4329)
[M::mem_pestat] mean and std.dev: (706.17, 780.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5719)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 242, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 720)
[M::mem_pestat] mean and std.dev: (264.93, 130.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 906)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (355, 460, 910)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2020)
[M::mem_pestat] mean and std.dev: (592.96, 403.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2575)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 594, 2574)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7218)
[M::mem_pestat] mean and std.dev: (1135.65, 1138.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9540)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698870 reads in 296.493 CPU sec, 9.608 real sec
sorting block 7, #reads = 1068525 mem = 536879227 peak = 889282560
[M::mem_process_seqs] Processed 697954 reads in 229.922 CPU sec, 7.408 real sec
[M::mem_process_seqs] Processed 698704 reads in 252.300 CPU sec, 8.148 real sec
sorting block 8, #reads = 1068863 mem = 536880285 peak = 889282560
[M::process] read 698366 sequences (100000163 bp) in 2.745 CPU sec, 2.990 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 279398, 15, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 298, 826)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2104)
[M::mem_pestat] mean and std.dev: (535.27, 571.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2819)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 241, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 706)
[M::mem_pestat] mean and std.dev: (263.23, 127.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 887)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (326, 626, 1977)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5279)
[M::mem_pestat] mean and std.dev: (1087.13, 913.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6930)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 365, 1081)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2803)
[M::mem_pestat] mean and std.dev: (664.25, 590.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3664)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698064 sequences (100000130 bp) in 2.283 CPU sec, 2.443 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 279265, 35, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 362, 517)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1069)
[M::mem_pestat] mean and std.dev: (321.53, 195.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1345)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 241, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 706)
[M::mem_pestat] mean and std.dev: (262.96, 127.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 887)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (489, 671, 1655)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3987)
[M::mem_pestat] mean and std.dev: (994.40, 794.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5153)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (304, 489, 1203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3001)
[M::mem_pestat] mean and std.dev: (674.13, 488.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3900)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698438 reads in 211.868 CPU sec, 6.747 real sec
[M::process] read 698782 sequences (100000221 bp) in 2.052 CPU sec, 2.076 real sec...
sorting block 9, #reads = 1067444 mem = 536881133 peak = 889282560
[M::mem_process_seqs] Processed 698366 reads in 143.395 CPU sec, 4.545 real sec
sorting block 10, #reads = 1067107 mem = 536877376 peak = 889282560
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 278846, 20, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 405, 620)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1476)
[M::mem_pestat] mean and std.dev: (384.55, 243.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1904)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 242, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 712)
[M::mem_pestat] mean and std.dev: (264.36, 128.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 895)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (625, 1915, 2956)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7618)
[M::mem_pestat] mean and std.dev: (2385.90, 2145.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10970)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 386, 947)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2367)
[M::mem_pestat] mean and std.dev: (533.11, 436.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3077)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699030 sequences (100000013 bp) in 2.647 CPU sec, 2.807 real sec...
[M::process] read 698430 sequences (100000290 bp) in 2.454 CPU sec, 2.462 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 278674, 32, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 586, 2839)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8077)
[M::mem_pestat] mean and std.dev: (1289.32, 1527.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10696)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 240, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 702)
[M::mem_pestat] mean and std.dev: (261.68, 126.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 882)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (568, 1187, 2858)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7438)
[M::mem_pestat] mean and std.dev: (1538.91, 1201.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9728)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (309, 687, 2171)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5895)
[M::mem_pestat] mean and std.dev: (1163.33, 1186.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7757)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698064 reads in 210.640 CPU sec, 6.709 real sec
[M::mem_process_seqs] Processed 698782 reads in 144.069 CPU sec, 4.607 real sec
sorting block 11, #reads = 1066004 mem = 536877273 peak = 889282560
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 279126, 23, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 342, 1180)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3178)
[M::mem_pestat] mean and std.dev: (654.18, 694.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4177)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 239, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 702)
[M::mem_pestat] mean and std.dev: (261.71, 127.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 882)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (252, 525, 1577)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4227)
[M::mem_pestat] mean and std.dev: (884.23, 812.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5552)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 315, 1462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4002)
[M::mem_pestat] mean and std.dev: (728.54, 722.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5272)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698206 sequences (100000180 bp) in 2.901 CPU sec, 3.097 real sec...
[M::process] read 698630 sequences (100000175 bp) in 2.039 CPU sec, 2.041 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 279227, 20, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 516, 1778)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4958)
[M::mem_pestat] mean and std.dev: (1081.95, 1102.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6548)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 241, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 708)
[M::mem_pestat] mean and std.dev: (262.88, 127.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 890)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 724, 1731)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4811)
[M::mem_pestat] mean and std.dev: (910.63, 930.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6351)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 426, 2581)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7295)
[M::mem_pestat] mean and std.dev: (1699.06, 2160.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10342)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699030 reads in 214.908 CPU sec, 6.850 real sec
[M::mem_process_seqs] Processed 698430 reads in 146.546 CPU sec, 4.670 real sec
sorting block 12, #reads = 1065306 mem = 536883350 peak = 889282560
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 278708, 21, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (249, 415, 2268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6306)
[M::mem_pestat] mean and std.dev: (1235.14, 1318.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8325)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 241, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 708)
[M::mem_pestat] mean and std.dev: (263.14, 128.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 890)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (306, 1463, 1464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3780)
[M::mem_pestat] mean and std.dev: (938.05, 629.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4938)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 345, 557)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1211)
[M::mem_pestat] mean and std.dev: (354.41, 219.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1538)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698334 sequences (100000119 bp) in 2.676 CPU sec, 2.809 real sec...
[M::process] read 698438 sequences (100000062 bp) in 2.060 CPU sec, 2.062 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 279276, 23, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 397, 1144)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2984)
[M::mem_pestat] mean and std.dev: (683.86, 667.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3904)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 241, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 711)
[M::mem_pestat] mean and std.dev: (263.62, 129.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 894)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (378, 532, 1402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3450)
[M::mem_pestat] mean and std.dev: (774.71, 619.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4474)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 366, 541)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1203)
[M::mem_pestat] mean and std.dev: (360.93, 220.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1534)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698206 reads in 207.720 CPU sec, 6.614 real sec
sorting block 13, #reads = 1066880 mem = 536879852 peak = 889282560
[M::mem_process_seqs] Processed 698630 reads in 141.197 CPU sec, 4.511 real sec
sorting block 14, #reads = 1066133 mem = 536876032 peak = 889282560
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 279043, 36, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 497, 1259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3377)
[M::mem_pestat] mean and std.dev: (793.58, 756.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4436)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 242, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 717)
[M::mem_pestat] mean and std.dev: (264.96, 130.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 902)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (380, 925, 2209)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5867)
[M::mem_pestat] mean and std.dev: (1329.35, 1272.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7696)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 334, 807)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1991)
[M::mem_pestat] mean and std.dev: (441.77, 341.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2583)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703282 sequences (100000120 bp) in 3.601 CPU sec, 3.924 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 278887, 13, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 352, 950)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2374)
[M::mem_pestat] mean and std.dev: (489.71, 526.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3086)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 242, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 715)
[M::mem_pestat] mean and std.dev: (264.61, 129.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 899)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (429, 701, 2329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6129)
[M::mem_pestat] mean and std.dev: (1068.83, 1148.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8029)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 377, 663)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1661)
[M::mem_pestat] mean and std.dev: (401.83, 301.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2160)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702882 sequences (100000228 bp) in 2.151 CPU sec, 2.153 real sec...
[M::mem_process_seqs] Processed 698334 reads in 218.670 CPU sec, 6.958 real sec
[M::mem_process_seqs] Processed 698438 reads in 152.820 CPU sec, 4.868 real sec
sorting block 15, #reads = 1065480 mem = 536877892 peak = 889282560
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281045, 18, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 344, 910)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2420)
[M::mem_pestat] mean and std.dev: (588.54, 618.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3175)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 229, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 677)
[M::mem_pestat] mean and std.dev: (251.91, 123.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 851)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (476, 1899, 2487)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6509)
[M::mem_pestat] mean and std.dev: (1814.94, 1600.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8520)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 336, 870)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2246)
[M::mem_pestat] mean and std.dev: (461.57, 436.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2934)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701766 sequences (100000079 bp) in 2.785 CPU sec, 2.941 real sec...
[M::process] read 700852 sequences (100000019 bp) in 2.200 CPU sec, 2.205 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 281238, 27, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 259, 632)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1576)
[M::mem_pestat] mean and std.dev: (332.97, 263.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2048)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 231, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 686)
[M::mem_pestat] mean and std.dev: (253.40, 124.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 863)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (490, 1022, 2016)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5068)
[M::mem_pestat] mean and std.dev: (1164.92, 1142.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6594)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 397, 970)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2532)
[M::mem_pestat] mean and std.dev: (604.03, 549.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3313)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703282 reads in 204.762 CPU sec, 6.516 real sec
[M::mem_process_seqs] Processed 702882 reads in 135.589 CPU sec, 4.378 real sec
sorting block 16, #reads = 1068303 mem = 536885021 peak = 889282560
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 281431, 16, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 521, 1168)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3032)
[M::mem_pestat] mean and std.dev: (821.86, 768.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3964)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 234, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 694)
[M::mem_pestat] mean and std.dev: (256.55, 125.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 873)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 278, 714)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1868)
[M::mem_pestat] mean and std.dev: (277.36, 270.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2445)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 325, 770)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1900)
[M::mem_pestat] mean and std.dev: (368.56, 326.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2465)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700274 sequences (100000172 bp) in 2.862 CPU sec, 3.032 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 280323, 26, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 394, 1475)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3995)
[M::mem_pestat] mean and std.dev: (553.37, 488.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5255)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (257.47, 125.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 874)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 362, 1103)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2975)
[M::mem_pestat] mean and std.dev: (600.71, 602.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3911)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 390, 1220)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3178)
[M::mem_pestat] mean and std.dev: (755.82, 714.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4157)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700180 sequences (100000071 bp) in 2.210 CPU sec, 2.216 real sec...
[M::mem_process_seqs] Processed 701766 reads in 200.050 CPU sec, 6.422 real sec
sorting block 17, #reads = 1073811 mem = 536876742 peak = 889282560
[M::mem_process_seqs] Processed 700852 reads in 133.116 CPU sec, 4.324 real sec
sorting block 18, #reads = 1073351 mem = 536878574 peak = 889282560
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 280542, 20, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 329, 799)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1969)
[M::mem_pestat] mean and std.dev: (466.42, 394.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2554)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 237, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (259.14, 126.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 880)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (120, 1064, 1674)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4782)
[M::mem_pestat] mean and std.dev: (1010.72, 1166.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6336)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (286, 827, 1568)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4132)
[M::mem_pestat] mean and std.dev: (824.30, 646.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5414)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700366 sequences (100000105 bp) in 2.779 CPU sec, 2.917 real sec...
[M::process] read 700018 sequences (100000049 bp) in 1.923 CPU sec, 1.932 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 280272, 23, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 249, 812)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2036)
[M::mem_pestat] mean and std.dev: (515.37, 524.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2648)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 238, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 706)
[M::mem_pestat] mean and std.dev: (260.63, 127.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 888)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 723, 1751)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4861)
[M::mem_pestat] mean and std.dev: (1073.09, 1203.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6416)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 381, 882)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2248)
[M::mem_pestat] mean and std.dev: (597.97, 572.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2931)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700274 reads in 206.924 CPU sec, 6.698 real sec
[M::mem_process_seqs] Processed 700180 reads in 136.256 CPU sec, 4.405 real sec
sorting block 19, #reads = 1071290 mem = 536876798 peak = 889282560
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 280609, 28, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 310, 1735)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4823)
[M::mem_pestat] mean and std.dev: (926.27, 1137.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6367)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 238, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709)
[M::mem_pestat] mean and std.dev: (261.15, 128.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 892)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 1059, 1801)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5029)
[M::mem_pestat] mean and std.dev: (671.95, 646.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6643)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 223, 434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 950)
[M::mem_pestat] mean and std.dev: (290.34, 172.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1208)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699656 sequences (100000189 bp) in 2.679 CPU sec, 2.807 real sec...
[M::process] read 699320 sequences (100000289 bp) in 1.859 CPU sec, 1.860 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 280283, 22, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 348, 931)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2435)
[M::mem_pestat] mean and std.dev: (451.16, 467.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3187)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 239, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 712)
[M::mem_pestat] mean and std.dev: (262.16, 129.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 896)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (461, 1531, 2325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6053)
[M::mem_pestat] mean and std.dev: (1417.10, 1220.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7917)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 296, 1452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4062)
[M::mem_pestat] mean and std.dev: (623.81, 866.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5367)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700366 reads in 208.472 CPU sec, 6.714 real sec
[M::mem_process_seqs] Processed 700018 reads in 137.729 CPU sec, 4.486 real sec
sorting block 20, #reads = 1069592 mem = 536878761 peak = 889282560
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 280494, 22, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 273, 558)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1258)
[M::mem_pestat] mean and std.dev: (276.81, 160.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1608)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 240, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 713)
[M::mem_pestat] mean and std.dev: (262.41, 128.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 897)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (575, 4867, 6620)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 18710)
[M::mem_pestat] mean and std.dev: (3659.91, 2865.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 24755)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (262, 438, 1427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3757)
[M::mem_pestat] mean and std.dev: (805.65, 801.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4922)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698968 sequences (100000083 bp) in 2.865 CPU sec, 2.983 real sec...
[M::process] read 698788 sequences (100000269 bp) in 1.867 CPU sec, 1.878 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 279718, 17, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 353, 632)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1474)
[M::mem_pestat] mean and std.dev: (329.55, 179.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1895)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 241, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 713)
[M::mem_pestat] mean and std.dev: (263.30, 129.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 897)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 429, 1083)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2915)
[M::mem_pestat] mean and std.dev: (562.53, 677.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3831)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 457, 1659)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4523)
[M::mem_pestat] mean and std.dev: (856.81, 906.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5955)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699656 reads in 208.215 CPU sec, 6.723 real sec
sorting block 21, #reads = 1070861 mem = 536878294 peak = 889282560
[M::mem_process_seqs] Processed 699320 reads in 137.837 CPU sec, 4.470 real sec
sorting block 22, #reads = 1070443 mem = 536881808 peak = 889282560
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 279505, 21, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 379, 541)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1141)
[M::mem_pestat] mean and std.dev: (343.34, 175.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1441)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 242, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 723)
[M::mem_pestat] mean and std.dev: (264.94, 130.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 910)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (40, 397, 1569)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4627)
[M::mem_pestat] mean and std.dev: (775.25, 940.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6156)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (287, 457, 1219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3083)
[M::mem_pestat] mean and std.dev: (808.62, 721.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4015)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698350 sequences (100000061 bp) in 2.812 CPU sec, 2.940 real sec...
[M::process] read 698438 sequences (100000096 bp) in 2.057 CPU sec, 2.059 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 280159, 39, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 331, 1423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3923)
[M::mem_pestat] mean and std.dev: (722.71, 844.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5173)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 242, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 717)
[M::mem_pestat] mean and std.dev: (264.59, 129.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 902)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (424, 952, 1319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3109)
[M::mem_pestat] mean and std.dev: (1115.38, 787.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4265)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 323, 826)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2024)
[M::mem_pestat] mean and std.dev: (461.27, 377.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2623)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698968 reads in 210.046 CPU sec, 6.780 real sec
[M::mem_process_seqs] Processed 698788 reads in 139.062 CPU sec, 4.501 real sec
sorting block 23, #reads = 1070090 mem = 536883819 peak = 889282560
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 279630, 21, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 503, 1090)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2814)
[M::mem_pestat] mean and std.dev: (677.77, 519.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3676)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 242, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 715)
[M::mem_pestat] mean and std.dev: (264.80, 129.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 899)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (659, 1129, 2071)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4895)
[M::mem_pestat] mean and std.dev: (1395.43, 987.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6307)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (277, 397, 1529)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4033)
[M::mem_pestat] mean and std.dev: (769.95, 689.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5285)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698894 sequences (100000030 bp) in 2.837 CPU sec, 2.960 real sec...
[M::process] read 698020 sequences (100000120 bp) in 2.031 CPU sec, 2.041 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 279768, 23, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 393, 1281)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3389)
[M::mem_pestat] mean and std.dev: (762.33, 819.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4443)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 242, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 714)
[M::mem_pestat] mean and std.dev: (263.82, 128.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 898)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (445, 833, 2033)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5209)
[M::mem_pestat] mean and std.dev: (1223.96, 1163.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6797)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 268, 1791)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5027)
[M::mem_pestat] mean and std.dev: (655.65, 862.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6645)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698350 reads in 210.725 CPU sec, 6.776 real sec
[M::mem_process_seqs] Processed 698438 reads in 139.465 CPU sec, 4.554 real sec
sorting block 24, #reads = 1068445 mem = 536879871 peak = 889282560
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 279411, 24, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 863, 1647)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4451)
[M::mem_pestat] mean and std.dev: (835.59, 782.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5853)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 242, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 717)
[M::mem_pestat] mean and std.dev: (264.74, 129.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 902)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (553, 1327, 3832)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10390)
[M::mem_pestat] mean and std.dev: (2251.33, 2504.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13669)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 358, 2368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6600)
[M::mem_pestat] mean and std.dev: (1718.34, 2221.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10604)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698450 sequences (100000164 bp) in 2.697 CPU sec, 2.843 real sec...
[M::process] read 699138 sequences (100000147 bp) in 1.838 CPU sec, 1.845 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 279694, 32, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 623, 1194)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3224)
[M::mem_pestat] mean and std.dev: (648.28, 693.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4239)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 244, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 716)
[M::mem_pestat] mean and std.dev: (265.47, 128.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 900)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 1211, 2372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6726)
[M::mem_pestat] mean and std.dev: (1386.22, 1361.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8903)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 351, 797)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1957)
[M::mem_pestat] mean and std.dev: (452.29, 359.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2537)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698894 reads in 211.187 CPU sec, 6.852 real sec
sorting block 25, #reads = 1068003 mem = 536879492 peak = 889282560
[M::mem_process_seqs] Processed 698020 reads in 142.359 CPU sec, 4.557 real sec
sorting block 26, #reads = 1068250 mem = 536879192 peak = 889282560
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 279314, 29, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 307, 1003)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2655)
[M::mem_pestat] mean and std.dev: (571.58, 716.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3481)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 241, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 717)
[M::mem_pestat] mean and std.dev: (264.27, 129.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 902)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (452, 1634, 5058)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 14270)
[M::mem_pestat] mean and std.dev: (2278.59, 2480.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 18876)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 415, 1119)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2923)
[M::mem_pestat] mean and std.dev: (583.71, 494.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3825)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698344 sequences (100000066 bp) in 2.841 CPU sec, 2.954 real sec...
[M::process] read 698854 sequences (100000015 bp) in 1.789 CPU sec, 1.789 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 279443, 28, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 527, 1365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3665)
[M::mem_pestat] mean and std.dev: (702.12, 694.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4815)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 239, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 707)
[M::mem_pestat] mean and std.dev: (261.85, 128.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 889)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 855, 2401)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6901)
[M::mem_pestat] mean and std.dev: (1201.39, 1361.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9151)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 301, 681)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1659)
[M::mem_pestat] mean and std.dev: (371.52, 278.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2148)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698450 reads in 207.840 CPU sec, 6.626 real sec
[M::mem_process_seqs] Processed 699138 reads in 141.646 CPU sec, 4.565 real sec
sorting block 27, #reads = 1068883 mem = 536880388 peak = 889282560
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 279243, 39, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 580, 2014)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5622)
[M::mem_pestat] mean and std.dev: (1024.63, 1101.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7426)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 242, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709)
[M::mem_pestat] mean and std.dev: (263.70, 128.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 891)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (451, 1208, 1834)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4600)
[M::mem_pestat] mean and std.dev: (928.36, 728.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5983)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 358, 1388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3676)
[M::mem_pestat] mean and std.dev: (615.70, 612.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4820)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698538 sequences (100000004 bp) in 2.765 CPU sec, 2.902 real sec...
[M::process] read 698664 sequences (100000202 bp) in 2.059 CPU sec, 2.067 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 279887, 30, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 616, 1321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3569)
[M::mem_pestat] mean and std.dev: (745.58, 782.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4693)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 239, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 702)
[M::mem_pestat] mean and std.dev: (261.62, 127.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 882)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (90, 334, 1430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4110)
[M::mem_pestat] mean and std.dev: (770.97, 899.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5450)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 320, 886)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2206)
[M::mem_pestat] mean and std.dev: (507.42, 433.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2866)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698344 reads in 210.692 CPU sec, 6.756 real sec
[M::mem_process_seqs] Processed 698854 reads in 140.985 CPU sec, 4.569 real sec
sorting block 28, #reads = 1066055 mem = 536884179 peak = 889282560
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 279432, 18, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (278, 356, 901)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2147)
[M::mem_pestat] mean and std.dev: (504.73, 371.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2770)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 240, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 705)
[M::mem_pestat] mean and std.dev: (262.68, 128.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 886)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (500, 1434, 2270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5810)
[M::mem_pestat] mean and std.dev: (1574.50, 1338.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7580)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 280, 835)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2125)
[M::mem_pestat] mean and std.dev: (609.40, 593.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2984)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698638 sequences (100000098 bp) in 2.770 CPU sec, 2.881 real sec...
[M::process] read 699016 sequences (100000300 bp) in 1.854 CPU sec, 1.856 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 278752, 31, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 329, 853)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2109)
[M::mem_pestat] mean and std.dev: (530.27, 444.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2737)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 240, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 708)
[M::mem_pestat] mean and std.dev: (262.52, 128.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 890)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (336, 851, 2473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6747)
[M::mem_pestat] mean and std.dev: (1141.80, 1005.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8884)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 332, 1035)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2791)
[M::mem_pestat] mean and std.dev: (600.04, 617.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3669)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698538 reads in 211.694 CPU sec, 6.819 real sec
sorting block 29, #reads = 1065736 mem = 536877997 peak = 889282560
[M::mem_process_seqs] Processed 698664 reads in 141.436 CPU sec, 4.553 real sec
sorting block 30, #reads = 1065905 mem = 536876357 peak = 889282560
[M::process] read 699134 sequences (100000281 bp) in 2.731 CPU sec, 2.862 real sec...
[M::process] read 701956 sequences (100000249 bp) in 1.909 CPU sec, 1.906 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 279608, 18, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 259, 823)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2131)
[M::mem_pestat] mean and std.dev: (367.41, 328.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2785)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 240, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 714)
[M::mem_pestat] mean and std.dev: (264.03, 130.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 898)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (102, 1053, 1454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4158)
[M::mem_pestat] mean and std.dev: (787.67, 686.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5510)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 321, 939)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2405)
[M::mem_pestat] mean and std.dev: (507.18, 527.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3138)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699016 reads in 117.064 CPU sec, 3.764 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 279248, 29, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (257, 453, 817)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1937)
[M::mem_pestat] mean and std.dev: (540.21, 477.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2497)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 241, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 711)
[M::mem_pestat] mean and std.dev: (263.79, 129.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 894)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (296, 468, 1175)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2933)
[M::mem_pestat] mean and std.dev: (638.21, 530.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3812)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 353, 979)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2477)
[M::mem_pestat] mean and std.dev: (602.40, 514.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3226)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 279505, 27, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 363, 933)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2407)
[M::mem_pestat] mean and std.dev: (507.94, 455.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3144)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 240, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 716)
[M::mem_pestat] mean and std.dev: (264.10, 130.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 901)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (538, 1108, 2609)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6751)
[M::mem_pestat] mean and std.dev: (1623.89, 1511.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8822)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 297, 644)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1562)
[M::mem_pestat] mean and std.dev: (355.78, 270.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2021)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702446 sequences (100000092 bp) in 2.163 CPU sec, 2.167 real sec...
[M::mem_process_seqs] Processed 698638 reads in 334.493 CPU sec, 10.733 real sec
sorting block 31, #reads = 1066064 mem = 536887510 peak = 889282560
[M::mem_process_seqs] Processed 699134 reads in 171.207 CPU sec, 5.643 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 280310, 22, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 557, 1245)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3313)
[M::mem_pestat] mean and std.dev: (687.82, 618.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4347)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 233, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (256.39, 126.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 869)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (764, 1520, 3061)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7655)
[M::mem_pestat] mean and std.dev: (2598.05, 2467.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12468)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 446, 1180)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3114)
[M::mem_pestat] mean and std.dev: (762.45, 701.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4081)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701704 sequences (100000141 bp) in 2.978 CPU sec, 3.164 real sec...
sorting block 32, #reads = 1067884 mem = 536880211 peak = 889282560
[M::process] read 701202 sequences (100000153 bp) in 1.945 CPU sec, 1.946 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 280814, 28, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 355, 706)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1712)
[M::mem_pestat] mean and std.dev: (439.28, 379.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2215)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 232, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (254.30, 124.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (693, 1250, 1645)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3549)
[M::mem_pestat] mean and std.dev: (1028.83, 506.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4501)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 357, 1211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3125)
[M::mem_pestat] mean and std.dev: (546.05, 489.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4082)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701956 reads in 211.853 CPU sec, 6.854 real sec
[M::mem_process_seqs] Processed 702446 reads in 143.563 CPU sec, 4.573 real sec
sorting block 33, #reads = 1068741 mem = 536882105 peak = 889282560
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 280939, 21, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 489, 980)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2542)
[M::mem_pestat] mean and std.dev: (616.10, 559.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3323)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 234, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (256.49, 125.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (278, 680, 1609)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4271)
[M::mem_pestat] mean and std.dev: (1013.52, 890.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5602)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 366, 1094)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2986)
[M::mem_pestat] mean and std.dev: (630.97, 756.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3932)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700102 sequences (100000142 bp) in 2.671 CPU sec, 2.828 real sec...
[M::process] read 700020 sequences (100000117 bp) in 1.919 CPU sec, 1.916 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 280301, 23, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 270, 666)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1610)
[M::mem_pestat] mean and std.dev: (349.43, 259.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2082)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 236, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (257.90, 126.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 875)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (86, 405, 737)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2039)
[M::mem_pestat] mean and std.dev: (361.16, 332.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2690)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 450, 1408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3740)
[M::mem_pestat] mean and std.dev: (777.53, 701.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4906)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701704 reads in 205.835 CPU sec, 6.573 real sec
[M::mem_process_seqs] Processed 701202 reads in 139.898 CPU sec, 4.560 real sec
sorting block 34, #reads = 1071143 mem = 536880627 peak = 889282560
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 279897, 25, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 312, 1353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3703)
[M::mem_pestat] mean and std.dev: (593.56, 621.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4878)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 238, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (259.60, 126.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 880)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (717, 1473, 2358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5640)
[M::mem_pestat] mean and std.dev: (1208.95, 803.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7281)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 241, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 994)
[M::mem_pestat] mean and std.dev: (272.62, 173.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1265)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699890 sequences (100000162 bp) in 2.656 CPU sec, 2.785 real sec...
[M::process] read 699484 sequences (100000009 bp) in 1.862 CPU sec, 1.871 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 279412, 29, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 867, 1564)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4198)
[M::mem_pestat] mean and std.dev: (797.27, 695.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5515)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 238, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709)
[M::mem_pestat] mean and std.dev: (261.08, 127.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 892)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (866, 2008, 3893)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9947)
[M::mem_pestat] mean and std.dev: (2829.14, 2749.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13826)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (265, 1000, 2087)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5731)
[M::mem_pestat] mean and std.dev: (1084.94, 1037.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7553)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700102 reads in 209.237 CPU sec, 6.765 real sec
sorting block 35, #reads = 1069769 mem = 536884855 peak = 889282560
[M::mem_process_seqs] Processed 700020 reads in 139.587 CPU sec, 4.554 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 279665, 46, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 455, 1061)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2759)
[M::mem_pestat] mean and std.dev: (628.89, 502.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3608)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 239, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709)
[M::mem_pestat] mean and std.dev: (261.51, 127.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 892)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (274, 830, 1031)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2545)
[M::mem_pestat] mean and std.dev: (560.10, 395.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3302)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (267, 373, 1049)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2613)
[M::mem_pestat] mean and std.dev: (441.97, 389.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3395)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699634 sequences (100000059 bp) in 2.897 CPU sec, 3.031 real sec...
[M::process] read 698724 sequences (100000116 bp) in 2.103 CPU sec, 2.108 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 279863, 30, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 343, 505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1197)
[M::mem_pestat] mean and std.dev: (291.10, 174.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1543)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 240, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 713)
[M::mem_pestat] mean and std.dev: (263.29, 129.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 897)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (427, 785, 981)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2089)
[M::mem_pestat] mean and std.dev: (633.96, 398.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2643)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 423, 933)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2307)
[M::mem_pestat] mean and std.dev: (579.15, 468.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2994)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699890 reads in 207.050 CPU sec, 6.674 real sec
sorting block 36, #reads = 1070262 mem = 536880356 peak = 889282560
[M::mem_process_seqs] Processed 699484 reads in 139.296 CPU sec, 4.454 real sec
sorting block 37, #reads = 1069442 mem = 536877597 peak = 889282560
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 279514, 24, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (300, 677, 1447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3741)
[M::mem_pestat] mean and std.dev: (912.21, 731.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4888)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 240, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 716)
[M::mem_pestat] mean and std.dev: (263.75, 130.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 901)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (370, 1110, 3365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9355)
[M::mem_pestat] mean and std.dev: (1948.57, 2208.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12350)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 280, 1710)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4726)
[M::mem_pestat] mean and std.dev: (882.84, 1159.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6234)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698492 sequences (100000129 bp) in 2.805 CPU sec, 2.922 real sec...
[M::process] read 698160 sequences (100000232 bp) in 1.869 CPU sec, 1.872 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 279287, 31, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 412, 784)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1890)
[M::mem_pestat] mean and std.dev: (351.40, 231.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2443)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 243, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 720)
[M::mem_pestat] mean and std.dev: (265.05, 130.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 906)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (512, 1454, 2324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5948)
[M::mem_pestat] mean and std.dev: (1695.14, 1729.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8615)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 364, 1684)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4642)
[M::mem_pestat] mean and std.dev: (730.14, 747.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6121)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699634 reads in 208.880 CPU sec, 6.678 real sec
[M::mem_process_seqs] Processed 698724 reads in 138.715 CPU sec, 4.513 real sec
sorting block 38, #reads = 1070352 mem = 536882786 peak = 889282560
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 279013, 32, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 406, 1165)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3139)
[M::mem_pestat] mean and std.dev: (694.35, 679.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4126)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 243, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 721)
[M::mem_pestat] mean and std.dev: (265.93, 130.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 907)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (286, 805, 2068)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5632)
[M::mem_pestat] mean and std.dev: (1147.73, 1251.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7414)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 682, 1753)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4765)
[M::mem_pestat] mean and std.dev: (1194.76, 1227.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6271)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697644 sequences (100000027 bp) in 2.814 CPU sec, 2.944 real sec...
[M::process] read 697978 sequences (100000005 bp) in 2.074 CPU sec, 2.082 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 279034, 26, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 306, 964)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2484)
[M::mem_pestat] mean and std.dev: (518.65, 477.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3244)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 721)
[M::mem_pestat] mean and std.dev: (266.01, 130.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 907)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (583, 1241, 2817)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7285)
[M::mem_pestat] mean and std.dev: (1474.73, 1083.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9519)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (324, 757, 3343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9381)
[M::mem_pestat] mean and std.dev: (1674.84, 1676.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12400)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698492 reads in 211.673 CPU sec, 6.822 real sec
sorting block 39, #reads = 1068463 mem = 536877289 peak = 889282560
[M::mem_process_seqs] Processed 698160 reads in 141.139 CPU sec, 4.610 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 279373, 24, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 261, 995)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2679)
[M::mem_pestat] mean and std.dev: (533.97, 583.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3521)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 244, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 722)
[M::mem_pestat] mean and std.dev: (266.82, 130.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 908)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (456, 828, 1328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3072)
[M::mem_pestat] mean and std.dev: (901.46, 616.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3944)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (316, 936, 2851)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7921)
[M::mem_pestat] mean and std.dev: (1556.75, 1677.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10456)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698164 sequences (100000038 bp) in 2.776 CPU sec, 2.915 real sec...
[M::process] read 698152 sequences (100000109 bp) in 1.828 CPU sec, 1.833 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 279280, 20, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 255, 412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 958)
[M::mem_pestat] mean and std.dev: (287.49, 220.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1231)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 244, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 716)
[M::mem_pestat] mean and std.dev: (266.02, 129.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 900)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (106, 282, 1148)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3232)
[M::mem_pestat] mean and std.dev: (540.05, 710.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4274)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 373, 921)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2261)
[M::mem_pestat] mean and std.dev: (491.56, 392.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2931)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697644 reads in 208.672 CPU sec, 6.774 real sec
sorting block 40, #reads = 1067116 mem = 536877808 peak = 889282560
[M::mem_process_seqs] Processed 697978 reads in 138.770 CPU sec, 4.531 real sec
sorting block 41, #reads = 1069207 mem = 536886653 peak = 889282560
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 279081, 23, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 312, 854)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2114)
[M::mem_pestat] mean and std.dev: (476.90, 406.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2744)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 242, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 712)
[M::mem_pestat] mean and std.dev: (264.27, 128.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 895)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (402, 933, 1700)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4296)
[M::mem_pestat] mean and std.dev: (1007.78, 789.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5594)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 548, 962)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2430)
[M::mem_pestat] mean and std.dev: (495.23, 376.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3164)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698028 sequences (100000177 bp) in 2.923 CPU sec, 3.062 real sec...
[M::process] read 698610 sequences (100000257 bp) in 1.933 CPU sec, 1.948 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 279403, 29, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 336, 902)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2306)
[M::mem_pestat] mean and std.dev: (372.56, 295.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3008)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 242, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 712)
[M::mem_pestat] mean and std.dev: (264.10, 128.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 895)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (365, 686, 1915)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5015)
[M::mem_pestat] mean and std.dev: (1165.75, 1138.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6565)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (299, 342, 613)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1241)
[M::mem_pestat] mean and std.dev: (405.84, 224.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1555)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698164 reads in 211.481 CPU sec, 6.841 real sec
[M::mem_process_seqs] Processed 698152 reads in 142.645 CPU sec, 4.670 real sec
sorting block 42, #reads = 1068033 mem = 536880135 peak = 889282560
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 279246, 23, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 305, 939)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2397)
[M::mem_pestat] mean and std.dev: (609.96, 599.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3126)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 240, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 706)
[M::mem_pestat] mean and std.dev: (262.91, 127.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 887)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 418, 2297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6521)
[M::mem_pestat] mean and std.dev: (1206.13, 1291.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8633)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (259, 427, 995)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2467)
[M::mem_pestat] mean and std.dev: (648.33, 529.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3203)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698472 sequences (100000136 bp) in 2.848 CPU sec, 3.010 real sec...
[M::process] read 698376 sequences (100000179 bp) in 2.027 CPU sec, 2.033 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 279305, 30, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (125, 180, 579)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1487)
[M::mem_pestat] mean and std.dev: (315.21, 307.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1941)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 239, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 702)
[M::mem_pestat] mean and std.dev: (261.60, 127.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 882)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (524, 1033, 2482)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6398)
[M::mem_pestat] mean and std.dev: (1599.03, 1611.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8356)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 295, 528)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1182)
[M::mem_pestat] mean and std.dev: (361.89, 242.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1509)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698028 reads in 215.340 CPU sec, 7.002 real sec
[M::mem_process_seqs] Processed 698610 reads in 145.412 CPU sec, 4.671 real sec
sorting block 43, #reads = 1068052 mem = 536881002 peak = 889282560
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 279466, 18, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 308, 1801)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4981)
[M::mem_pestat] mean and std.dev: (857.57, 930.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6571)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 240, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 702)
[M::mem_pestat] mean and std.dev: (262.05, 126.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 882)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 730, 1000)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2608)
[M::mem_pestat] mean and std.dev: (637.72, 470.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3412)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 242, 544)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1276)
[M::mem_pestat] mean and std.dev: (334.12, 273.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1642)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698616 sequences (100000140 bp) in 3.002 CPU sec, 3.147 real sec...
[M::process] read 698744 sequences (100000243 bp) in 1.962 CPU sec, 1.969 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 279659, 37, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 313, 1010)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2594)
[M::mem_pestat] mean and std.dev: (511.68, 555.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3386)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 240, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 702)
[M::mem_pestat] mean and std.dev: (262.02, 126.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 882)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 843, 1602)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4378)
[M::mem_pestat] mean and std.dev: (991.92, 869.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5766)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 294, 591)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1453)
[M::mem_pestat] mean and std.dev: (372.20, 294.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1884)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698472 reads in 216.467 CPU sec, 6.918 real sec
sorting block 44, #reads = 1067172 mem = 536880071 peak = 889282560
[M::mem_process_seqs] Processed 698376 reads in 143.499 CPU sec, 4.567 real sec
sorting block 45, #reads = 1067191 mem = 536879872 peak = 899133440
[M::process] read 698878 sequences (100000006 bp) in 2.895 CPU sec, 3.007 real sec...
[M::process] read 698692 sequences (100000077 bp) in 2.077 CPU sec, 2.085 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 279151, 34, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 287, 1100)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2948)
[M::mem_pestat] mean and std.dev: (608.19, 609.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3872)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 240, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 702)
[M::mem_pestat] mean and std.dev: (261.70, 127.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 882)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (536, 1798, 2418)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6182)
[M::mem_pestat] mean and std.dev: (1560.56, 1124.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8064)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 339, 972)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2502)
[M::mem_pestat] mean and std.dev: (531.48, 469.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3267)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698744 reads in 116.975 CPU sec, 3.763 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 279666, 21, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 252, 545)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1315)
[M::mem_pestat] mean and std.dev: (372.51, 298.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1700)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 239, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (261.02, 126.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 878)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1211, 1643, 6105)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 15893)
[M::mem_pestat] mean and std.dev: (2889.29, 2740.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 20787)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 303, 900)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2256)
[M::mem_pestat] mean and std.dev: (480.17, 415.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2934)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 280004, 26, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 244, 635)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1539)
[M::mem_pestat] mean and std.dev: (368.51, 256.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1991)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 240, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 708)
[M::mem_pestat] mean and std.dev: (262.75, 128.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 890)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (587, 1368, 1522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3392)
[M::mem_pestat] mean and std.dev: (1171.50, 789.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4329)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 310, 602)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1462)
[M::mem_pestat] mean and std.dev: (312.51, 253.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1892)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698336 sequences (100000120 bp) in 2.222 CPU sec, 2.227 real sec...
[M::mem_process_seqs] Processed 698616 reads in 334.087 CPU sec, 10.797 real sec
sorting block 46, #reads = 1066515 mem = 536876738 peak = 899133440
[M::mem_process_seqs] Processed 698878 reads in 173.569 CPU sec, 5.604 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 279536, 17, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 294, 1434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3940)
[M::mem_pestat] mean and std.dev: (636.44, 762.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5193)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 241, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 717)
[M::mem_pestat] mean and std.dev: (264.34, 130.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 902)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (445, 633, 1485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3565)
[M::mem_pestat] mean and std.dev: (899.56, 608.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4605)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 428, 1486)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4018)
[M::mem_pestat] mean and std.dev: (816.43, 924.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5284)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 47, #reads = 1068256 mem = 536882906 peak = 899133440
[M::process] read 698712 sequences (100000193 bp) in 3.046 CPU sec, 3.223 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 279430, 16, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 241, 514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1244)
[M::mem_pestat] mean and std.dev: (323.26, 260.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1609)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 241, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 714)
[M::mem_pestat] mean and std.dev: (264.24, 129.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 898)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1120, 1598, 4559)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11437)
[M::mem_pestat] mean and std.dev: (2615.25, 2399.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14876)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 238, 1133)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3039)
[M::mem_pestat] mean and std.dev: (502.86, 601.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3992)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703000 sequences (100000239 bp) in 2.206 CPU sec, 2.212 real sec...
[M::mem_process_seqs] Processed 698692 reads in 205.953 CPU sec, 6.555 real sec
[M::mem_process_seqs] Processed 698336 reads in 141.608 CPU sec, 4.750 real sec
sorting block 48, #reads = 1068095 mem = 536878984 peak = 899133440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 278994, 19, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 369, 1242)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3450)
[M::mem_pestat] mean and std.dev: (598.58, 606.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4554)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 242, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 723)
[M::mem_pestat] mean and std.dev: (265.93, 132.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 910)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 263, 889)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2295)
[M::mem_pestat] mean and std.dev: (505.94, 433.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2998)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 420, 1605)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4395)
[M::mem_pestat] mean and std.dev: (820.37, 993.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5790)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701708 sequences (100000292 bp) in 2.869 CPU sec, 3.000 real sec...
[M::process] read 701130 sequences (100000226 bp) in 2.168 CPU sec, 2.172 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 280738, 27, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 272, 855)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2193)
[M::mem_pestat] mean and std.dev: (509.00, 529.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2862)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 230, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 681)
[M::mem_pestat] mean and std.dev: (253.05, 124.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 856)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 1233, 2460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7030)
[M::mem_pestat] mean and std.dev: (1741.41, 1946.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9527)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 558, 1736)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4780)
[M::mem_pestat] mean and std.dev: (794.91, 728.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6302)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698712 reads in 205.742 CPU sec, 6.787 real sec
[M::mem_process_seqs] Processed 703000 reads in 136.435 CPU sec, 4.445 real sec
sorting block 49, #reads = 1066980 mem = 536882501 peak = 899133440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 280528, 32, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 288, 1219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3203)
[M::mem_pestat] mean and std.dev: (655.76, 713.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4195)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 234, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (256.37, 125.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (647, 923, 3026)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7784)
[M::mem_pestat] mean and std.dev: (1553.69, 1258.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10163)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 441, 1203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3155)
[M::mem_pestat] mean and std.dev: (563.68, 469.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4131)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700396 sequences (100000197 bp) in 2.799 CPU sec, 2.933 real sec...
[M::process] read 699450 sequences (100000060 bp) in 2.124 CPU sec, 2.127 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 279963, 24, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 260, 474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1126)
[M::mem_pestat] mean and std.dev: (272.94, 186.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1452)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701)
[M::mem_pestat] mean and std.dev: (258.74, 128.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 882)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (659, 1222, 3646)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9620)
[M::mem_pestat] mean and std.dev: (2230.17, 2142.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12607)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 320, 929)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2391)
[M::mem_pestat] mean and std.dev: (491.63, 477.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3122)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701708 reads in 202.348 CPU sec, 6.541 real sec
sorting block 50, #reads = 1068666 mem = 536880736 peak = 899133440
[M::mem_process_seqs] Processed 701130 reads in 136.222 CPU sec, 4.442 real sec
sorting block 51, #reads = 1072091 mem = 536877243 peak = 899133440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 279968, 34, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 265, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 971)
[M::mem_pestat] mean and std.dev: (244.88, 115.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1241)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 237, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 708)
[M::mem_pestat] mean and std.dev: (260.20, 127.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 891)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (445, 605, 897)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1801)
[M::mem_pestat] mean and std.dev: (543.93, 272.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2253)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 427, 1224)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3324)
[M::mem_pestat] mean and std.dev: (561.09, 505.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4374)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699742 sequences (100000112 bp) in 2.707 CPU sec, 2.865 real sec...
[M::process] read 699404 sequences (100000114 bp) in 2.071 CPU sec, 2.079 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 280147, 25, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 492, 1565)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4311)
[M::mem_pestat] mean and std.dev: (919.32, 1057.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5684)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 240, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 704)
[M::mem_pestat] mean and std.dev: (261.45, 127.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 885)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (417, 476, 925)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1941)
[M::mem_pestat] mean and std.dev: (625.92, 455.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2449)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 241, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 712)
[M::mem_pestat] mean and std.dev: (256.46, 109.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 888)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700396 reads in 200.939 CPU sec, 6.512 real sec
[M::mem_process_seqs] Processed 699450 reads in 135.231 CPU sec, 4.330 real sec
sorting block 52, #reads = 1071846 mem = 536880663 peak = 899133440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 279766, 24, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 461, 1558)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4320)
[M::mem_pestat] mean and std.dev: (803.62, 780.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5701)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 240, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 710)
[M::mem_pestat] mean and std.dev: (262.59, 129.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 893)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 608, 1000)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2624)
[M::mem_pestat] mean and std.dev: (645.39, 671.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3436)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 408, 1296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3516)
[M::mem_pestat] mean and std.dev: (785.33, 783.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4626)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699516 sequences (100000042 bp) in 2.973 CPU sec, 3.165 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 279784, 26, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (258, 401, 1200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3084)
[M::mem_pestat] mean and std.dev: (655.94, 653.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4026)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 241, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 722)
[M::mem_pestat] mean and std.dev: (264.44, 130.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 909)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (67, 338, 1213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3505)
[M::mem_pestat] mean and std.dev: (662.42, 948.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4651)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (266, 424, 1311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3401)
[M::mem_pestat] mean and std.dev: (645.91, 620.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4446)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699000 sequences (100000229 bp) in 2.058 CPU sec, 2.062 real sec...
[M::mem_process_seqs] Processed 699742 reads in 205.119 CPU sec, 6.562 real sec
[M::mem_process_seqs] Processed 699404 reads in 137.524 CPU sec, 4.389 real sec
sorting block 53, #reads = 1071079 mem = 536880946 peak = 899133440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 279792, 34, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 450, 907)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2247)
[M::mem_pestat] mean and std.dev: (511.98, 399.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2917)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 240, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 722)
[M::mem_pestat] mean and std.dev: (264.82, 131.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 909)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (370, 717, 1034)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2362)
[M::mem_pestat] mean and std.dev: (721.85, 444.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3026)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 359, 1308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3508)
[M::mem_pestat] mean and std.dev: (681.45, 792.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4608)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698508 sequences (100000219 bp) in 2.840 CPU sec, 2.993 real sec...
[M::process] read 698518 sequences (100000295 bp) in 1.850 CPU sec, 1.852 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 279804, 25, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 254, 700)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1736)
[M::mem_pestat] mean and std.dev: (331.94, 305.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2254)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 241, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 720)
[M::mem_pestat] mean and std.dev: (265.03, 131.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 906)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (341, 756, 1060)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2498)
[M::mem_pestat] mean and std.dev: (691.48, 448.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3217)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 413, 1782)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5014)
[M::mem_pestat] mean and std.dev: (755.58, 944.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6630)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699516 reads in 202.911 CPU sec, 6.489 real sec
sorting block 54, #reads = 1071692 mem = 536890103 peak = 899133440
[M::mem_process_seqs] Processed 699000 reads in 135.339 CPU sec, 4.330 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 279902, 26, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 201, 482)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1158)
[M::mem_pestat] mean and std.dev: (221.25, 123.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1496)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 243, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 724)
[M::mem_pestat] mean and std.dev: (266.26, 131.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 911)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (491, 702, 931)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1811)
[M::mem_pestat] mean and std.dev: (603.09, 292.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2251)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 509, 987)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2643)
[M::mem_pestat] mean and std.dev: (599.81, 524.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3471)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 55, #reads = 1070884 mem = 536877457 peak = 899133440
[M::process] read 698568 sequences (100000080 bp) in 2.862 CPU sec, 3.020 real sec...
[M::process] read 697850 sequences (100000210 bp) in 2.109 CPU sec, 2.119 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 279715, 22, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 471, 935)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2399)
[M::mem_pestat] mean and std.dev: (696.92, 625.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3197)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 243, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 724)
[M::mem_pestat] mean and std.dev: (266.44, 131.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 911)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (787, 1103, 1270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2236)
[M::mem_pestat] mean and std.dev: (905.47, 474.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2802)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 405, 554)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1212)
[M::mem_pestat] mean and std.dev: (370.35, 206.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1541)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698508 reads in 205.885 CPU sec, 6.581 real sec
[M::mem_process_seqs] Processed 698518 reads in 139.485 CPU sec, 4.551 real sec
sorting block 56, #reads = 1070054 mem = 536884159 peak = 899133440
[M::process] read 697318 sequences (100000212 bp) in 2.898 CPU sec, 3.022 real sec...
[M::process] read 698786 sequences (100000195 bp) in 1.874 CPU sec, 1.876 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 279344, 20, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 448, 1711)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4723)
[M::mem_pestat] mean and std.dev: (885.07, 970.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6229)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 244, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 719)
[M::mem_pestat] mean and std.dev: (266.43, 130.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 904)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (426, 774, 1991)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5121)
[M::mem_pestat] mean and std.dev: (1213.70, 1177.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6686)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 297, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (42, 552)
[M::mem_pestat] mean and std.dev: (274.69, 76.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 654)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697850 reads in 110.966 CPU sec, 3.562 real sec
sorting block 57, #reads = 1068912 mem = 536884959 peak = 899133440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 279691, 14, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 559, 1463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3967)
[M::mem_pestat] mean and std.dev: (865.78, 923.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5219)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 242, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 720)
[M::mem_pestat] mean and std.dev: (265.11, 130.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 906)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (352, 965, 1622)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4162)
[M::mem_pestat] mean and std.dev: (805.42, 523.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5432)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 263, 586)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1442)
[M::mem_pestat] mean and std.dev: (340.87, 257.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1870)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 278892, 16, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 448, 892)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2332)
[M::mem_pestat] mean and std.dev: (476.85, 461.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3052)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 245, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 723)
[M::mem_pestat] mean and std.dev: (267.96, 130.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 909)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (848, 1000, 1637)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3215)
[M::mem_pestat] mean and std.dev: (934.43, 589.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4004)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 392, 1035)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2723)
[M::mem_pestat] mean and std.dev: (648.45, 678.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3567)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698738 sequences (100000149 bp) in 2.315 CPU sec, 2.322 real sec...
[M::mem_process_seqs] Processed 698568 reads in 314.289 CPU sec, 10.144 real sec
[M::mem_process_seqs] Processed 697318 reads in 165.739 CPU sec, 5.447 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 279957, 32, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 624, 1211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3153)
[M::mem_pestat] mean and std.dev: (728.72, 614.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4124)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 239, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 702)
[M::mem_pestat] mean and std.dev: (261.53, 127.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 882)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 398, 1092)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2950)
[M::mem_pestat] mean and std.dev: (516.96, 607.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3879)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (277, 682, 1070)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2656)
[M::mem_pestat] mean and std.dev: (809.84, 679.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3528)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 58, #reads = 1067896 mem = 536880049 peak = 899133440
[M::process] read 698772 sequences (100000296 bp) in 4.124 CPU sec, 4.541 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 279457, 24, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (127, 306, 700)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1846)
[M::mem_pestat] mean and std.dev: (386.57, 310.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2419)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 238, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (259.96, 125.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 873)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 517, 1614)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4416)
[M::mem_pestat] mean and std.dev: (758.86, 762.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5817)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 484, 1357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3647)
[M::mem_pestat] mean and std.dev: (842.50, 877.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4792)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698786 reads in 198.758 CPU sec, 6.442 real sec
[M::mem_process_seqs] Processed 698738 reads in 137.315 CPU sec, 4.364 real sec
[M::process] read 698578 sequences (100000002 bp) in 3.552 CPU sec, 3.914 real sec...
sorting block 59, #reads = 1068070 mem = 536879813 peak = 899133440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 278814, 36, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 574, 1337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3695)
[M::mem_pestat] mean and std.dev: (842.49, 848.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4874)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 239, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 702)
[M::mem_pestat] mean and std.dev: (261.48, 127.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 882)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (424, 854, 2263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5941)
[M::mem_pestat] mean and std.dev: (923.97, 803.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7780)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 346, 1125)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2963)
[M::mem_pestat] mean and std.dev: (570.75, 511.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3882)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 279644, 19, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 205, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701)
[M::mem_pestat] mean and std.dev: (221.60, 101.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 875)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 238, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 702)
[M::mem_pestat] mean and std.dev: (261.19, 126.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 882)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (394, 749, 1824)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4684)
[M::mem_pestat] mean and std.dev: (1158.44, 1360.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6599)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 281, 716)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1748)
[M::mem_pestat] mean and std.dev: (414.67, 330.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2264)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698742 sequences (100000141 bp) in 3.207 CPU sec, 3.550 real sec...
[M::mem_process_seqs] Processed 698772 reads in 201.075 CPU sec, 6.471 real sec
[M::mem_process_seqs] Processed 698578 reads in 136.147 CPU sec, 4.338 real sec
sorting block 60, #reads = 1068951 mem = 536878843 peak = 899133440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 279443, 27, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 237, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1023)
[M::mem_pestat] mean and std.dev: (268.78, 182.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1314)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 239, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (260.75, 126.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 878)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 427, 1417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3829)
[M::mem_pestat] mean and std.dev: (760.88, 780.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5035)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 425, 1290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3496)
[M::mem_pestat] mean and std.dev: (821.42, 804.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4599)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698848 sequences (100000036 bp) in 3.652 CPU sec, 3.933 real sec...
[M::mem_process_seqs] Processed 698742 reads in 113.081 CPU sec, 3.744 real sec
sorting block 61, #reads = 1067336 mem = 536880534 peak = 899133440
[M::process] read 698674 sequences (100000118 bp) in 3.097 CPU sec, 3.288 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 279375, 21, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 287, 1060)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2850)
[M::mem_pestat] mean and std.dev: (542.34, 632.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3745)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 239, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (260.68, 126.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 874)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (538, 871, 1476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3352)
[M::mem_pestat] mean and std.dev: (895.63, 554.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4290)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (259, 479, 1427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3763)
[M::mem_pestat] mean and std.dev: (933.59, 838.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4931)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698788 sequences (100000023 bp) in 2.411 CPU sec, 2.503 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 279055, 27, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 367, 698)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1776)
[M::mem_pestat] mean and std.dev: (411.88, 337.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2315)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 241, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (262.23, 127.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (417, 987, 2072)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5382)
[M::mem_pestat] mean and std.dev: (1292.67, 995.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7037)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 334, 983)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2491)
[M::mem_pestat] mean and std.dev: (527.14, 553.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3245)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698848 reads in 197.039 CPU sec, 6.285 real sec
[M::mem_process_seqs] Processed 698674 reads in 135.621 CPU sec, 4.285 real sec
[M::process] read 698936 sequences (100000281 bp) in 2.405 CPU sec, 2.492 real sec...
sorting block 62, #reads = 1067560 mem = 536878231 peak = 899133440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 279746, 35, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (254, 661, 1329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3479)
[M::mem_pestat] mean and std.dev: (750.10, 573.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4554)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 240, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 707)
[M::mem_pestat] mean and std.dev: (261.91, 127.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 889)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (316, 536, 1401)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3571)
[M::mem_pestat] mean and std.dev: (863.60, 670.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4656)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 255, 1037)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2783)
[M::mem_pestat] mean and std.dev: (562.14, 636.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3656)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 63, #reads = 1067896 mem = 536880441 peak = 899133440
[M::process] read 697352 sequences (100000094 bp) in 3.299 CPU sec, 3.476 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 279235, 17, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 282, 619)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1565)
[M::mem_pestat] mean and std.dev: (353.89, 290.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2038)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 240, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 708)
[M::mem_pestat] mean and std.dev: (262.53, 128.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 890)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (724, 914, 1975)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4477)
[M::mem_pestat] mean and std.dev: (1038.73, 993.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5728)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 530, 924)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2332)
[M::mem_pestat] mean and std.dev: (678.37, 536.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3036)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698788 reads in 206.496 CPU sec, 6.598 real sec
[M::process] read 698634 sequences (100000173 bp) in 2.453 CPU sec, 2.500 real sec...
[M::mem_process_seqs] Processed 698936 reads in 146.458 CPU sec, 4.770 real sec
sorting block 64, #reads = 1067894 mem = 536879101 peak = 899133440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 279115, 42, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 345, 770)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1902)
[M::mem_pestat] mean and std.dev: (370.64, 314.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2468)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 245, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 725)
[M::mem_pestat] mean and std.dev: (267.83, 131.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 912)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (306, 643, 1517)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3939)
[M::mem_pestat] mean and std.dev: (905.58, 907.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5150)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 251, 554)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1250)
[M::mem_pestat] mean and std.dev: (325.46, 249.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1598)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700678 sequences (100000001 bp) in 2.770 CPU sec, 2.893 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 279830, 42, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 306, 1250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3394)
[M::mem_pestat] mean and std.dev: (683.24, 744.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4466)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 241, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 714)
[M::mem_pestat] mean and std.dev: (264.41, 130.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 898)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (411, 1003, 1931)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4971)
[M::mem_pestat] mean and std.dev: (1232.74, 912.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6491)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 286, 474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1012)
[M::mem_pestat] mean and std.dev: (289.65, 152.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1281)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708358 sequences (100000291 bp) in 2.146 CPU sec, 2.158 real sec...
[M::mem_process_seqs] Processed 697352 reads in 209.372 CPU sec, 6.843 real sec
[M::mem_process_seqs] Processed 698634 reads in 141.513 CPU sec, 4.573 real sec
sorting block 65, #reads = 1067014 mem = 536879474 peak = 899133440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 279741, 34, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 267, 1714)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4840)
[M::mem_pestat] mean and std.dev: (724.66, 940.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6403)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 234, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (258.71, 128.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (631, 1211, 2705)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6853)
[M::mem_pestat] mean and std.dev: (1489.87, 1207.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8927)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 320, 1191)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3195)
[M::mem_pestat] mean and std.dev: (719.05, 731.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4197)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706118 sequences (100000259 bp) in 2.838 CPU sec, 2.946 real sec...
[M::process] read 704882 sequences (100000246 bp) in 1.879 CPU sec, 1.886 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 283134, 21, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 412, 1431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3845)
[M::mem_pestat] mean and std.dev: (760.83, 714.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5052)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 215, 311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 637)
[M::mem_pestat] mean and std.dev: (239.50, 118.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 800)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (378, 892, 2094)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5526)
[M::mem_pestat] mean and std.dev: (1397.10, 1422.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7242)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 652, 1269)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3399)
[M::mem_pestat] mean and std.dev: (735.86, 773.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4464)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700678 reads in 216.385 CPU sec, 6.958 real sec
[M::mem_process_seqs] Processed 708358 reads in 145.796 CPU sec, 4.662 real sec
sorting block 66, #reads = 1067075 mem = 536877795 peak = 899133440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 282717, 29, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 325, 1194)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3204)
[M::mem_pestat] mean and std.dev: (566.67, 565.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4209)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 221, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (245.81, 122.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 831)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (547, 768, 1297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2797)
[M::mem_pestat] mean and std.dev: (907.62, 536.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3547)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 315, 1048)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2724)
[M::mem_pestat] mean and std.dev: (425.52, 390.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3562)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704206 sequences (100000103 bp) in 2.745 CPU sec, 2.861 real sec...
[M::process] read 703034 sequences (100000223 bp) in 2.149 CPU sec, 2.144 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 282258, 18, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 506, 1491)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4149)
[M::mem_pestat] mean and std.dev: (880.04, 928.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5478)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 224, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 669)
[M::mem_pestat] mean and std.dev: (249.11, 124.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 841)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (297, 738, 819)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1863)
[M::mem_pestat] mean and std.dev: (552.38, 276.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2385)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 307, 900)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2230)
[M::mem_pestat] mean and std.dev: (509.10, 481.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2895)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706118 reads in 205.897 CPU sec, 6.545 real sec
sorting block 67, #reads = 1067914 mem = 536878617 peak = 899133440
[M::mem_process_seqs] Processed 704882 reads in 137.242 CPU sec, 4.609 real sec
sorting block 68, #reads = 1070726 mem = 536879084 peak = 899133440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 282251, 17, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 297, 833)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2115)
[M::mem_pestat] mean and std.dev: (448.00, 388.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2756)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 225, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 678)
[M::mem_pestat] mean and std.dev: (251.26, 126.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 853)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (489, 505, 2298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5916)
[M::mem_pestat] mean and std.dev: (1401.35, 1431.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7725)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 247, 568)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1360)
[M::mem_pestat] mean and std.dev: (343.00, 285.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1756)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702392 sequences (100000134 bp) in 2.812 CPU sec, 2.956 real sec...
[M::process] read 701184 sequences (100000059 bp) in 1.934 CPU sec, 1.945 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 281879, 25, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 209, 514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1236)
[M::mem_pestat] mean and std.dev: (298.81, 224.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1597)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 230, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (255.40, 127.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 875)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (452, 1245, 2614)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6938)
[M::mem_pestat] mean and std.dev: (1340.29, 1021.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9100)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 317, 1175)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3077)
[M::mem_pestat] mean and std.dev: (568.06, 583.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4028)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704206 reads in 205.658 CPU sec, 6.793 real sec
[M::mem_process_seqs] Processed 703034 reads in 133.533 CPU sec, 4.360 real sec
sorting block 69, #reads = 1069548 mem = 536878970 peak = 899133440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 282233, 15, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 385, 1892)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5268)
[M::mem_pestat] mean and std.dev: (1242.58, 1476.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7150)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 231, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 702)
[M::mem_pestat] mean and std.dev: (257.70, 129.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 884)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 489, 1903)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5261)
[M::mem_pestat] mean and std.dev: (816.79, 768.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6940)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (303, 527, 973)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2313)
[M::mem_pestat] mean and std.dev: (516.71, 313.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2983)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701806 sequences (100000144 bp) in 2.779 CPU sec, 2.905 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 280687, 30, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 278, 1162)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3164)
[M::mem_pestat] mean and std.dev: (536.61, 621.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4165)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 713)
[M::mem_pestat] mean and std.dev: (260.91, 131.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 898)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (570, 896, 3132)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8256)
[M::mem_pestat] mean and std.dev: (1722.59, 1540.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10818)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 371, 1153)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3039)
[M::mem_pestat] mean and std.dev: (549.91, 575.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3982)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701202 sequences (100000090 bp) in 2.288 CPU sec, 2.288 real sec...
[M::mem_process_seqs] Processed 702392 reads in 203.432 CPU sec, 6.567 real sec
[M::mem_process_seqs] Processed 701184 reads in 134.256 CPU sec, 4.328 real sec
sorting block 70, #reads = 1070733 mem = 536879817 peak = 899133440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 281357, 25, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (292, 424, 1141)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2839)
[M::mem_pestat] mean and std.dev: (671.73, 585.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3688)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 234, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709)
[M::mem_pestat] mean and std.dev: (259.60, 130.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 893)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (119, 790, 3540)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10382)
[M::mem_pestat] mean and std.dev: (1699.08, 1945.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13803)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (294, 438, 672)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1428)
[M::mem_pestat] mean and std.dev: (395.76, 205.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1806)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701170 sequences (100000079 bp) in 3.127 CPU sec, 3.323 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 281186, 31, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 306, 828)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2150)
[M::mem_pestat] mean and std.dev: (448.86, 453.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2811)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 234, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 710)
[M::mem_pestat] mean and std.dev: (260.38, 130.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 894)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (430, 805, 2413)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6379)
[M::mem_pestat] mean and std.dev: (1220.63, 1107.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8362)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (276, 334, 1582)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4194)
[M::mem_pestat] mean and std.dev: (859.00, 825.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5500)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701366 sequences (100000188 bp) in 2.401 CPU sec, 2.425 real sec...
[M::mem_process_seqs] Processed 701806 reads in 220.760 CPU sec, 7.116 real sec
sorting block 71, #reads = 1069510 mem = 536884942 peak = 899133440
[M::mem_process_seqs] Processed 701202 reads in 148.923 CPU sec, 4.846 real sec
sorting block 72, #reads = 1069366 mem = 536879046 peak = 899133440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 281337, 27, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 344, 548)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1316)
[M::mem_pestat] mean and std.dev: (318.54, 228.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1700)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 713)
[M::mem_pestat] mean and std.dev: (260.85, 130.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 898)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (585, 1022, 1834)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4332)
[M::mem_pestat] mean and std.dev: (1036.73, 749.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5581)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 188, 380)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 780)
[M::mem_pestat] mean and std.dev: (222.71, 96.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 980)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701282 sequences (100000204 bp) in 2.978 CPU sec, 3.127 real sec...
[M::process] read 701750 sequences (100000007 bp) in 2.033 CPU sec, 2.040 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281165, 23, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (281, 734, 2104)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5750)
[M::mem_pestat] mean and std.dev: (1159.39, 1066.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7573)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 234, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 710)
[M::mem_pestat] mean and std.dev: (259.88, 129.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 894)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (514, 1082, 1973)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4891)
[M::mem_pestat] mean and std.dev: (1214.50, 807.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6350)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 315, 987)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2591)
[M::mem_pestat] mean and std.dev: (484.93, 477.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3393)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701170 reads in 226.614 CPU sec, 7.346 real sec
[M::mem_process_seqs] Processed 701366 reads in 148.539 CPU sec, 4.858 real sec
sorting block 73, #reads = 1066412 mem = 536879105 peak = 899133440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 281320, 27, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 528, 996)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2624)
[M::mem_pestat] mean and std.dev: (735.88, 689.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3493)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 713)
[M::mem_pestat] mean and std.dev: (260.65, 130.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 898)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (277, 881, 3216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9094)
[M::mem_pestat] mean and std.dev: (1721.11, 1768.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12033)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 683, 3109)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8877)
[M::mem_pestat] mean and std.dev: (1566.00, 1963.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11761)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700610 sequences (100000201 bp) in 4.377 CPU sec, 4.768 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 281100, 37, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 263, 837)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2133)
[M::mem_pestat] mean and std.dev: (535.26, 519.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2781)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 233, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (257.82, 128.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 881)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (479, 1095, 1685)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4097)
[M::mem_pestat] mean and std.dev: (999.06, 803.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5303)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 275, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1022)
[M::mem_pestat] mean and std.dev: (288.95, 152.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1302)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701282 reads in 231.146 CPU sec, 7.580 real sec
[M::mem_process_seqs] Processed 701750 reads in 159.110 CPU sec, 5.119 real sec
[M::process] read 700110 sequences (100000161 bp) in 3.238 CPU sec, 3.371 real sec...
sorting block 74, #reads = 1067834 mem = 536885847 peak = 899133440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 280624, 23, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 438, 1022)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2580)
[M::mem_pestat] mean and std.dev: (650.24, 621.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3359)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 235, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 708)
[M::mem_pestat] mean and std.dev: (260.94, 130.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 891)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (344, 953, 1835)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4817)
[M::mem_pestat] mean and std.dev: (1217.48, 988.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6308)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 326, 875)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2221)
[M::mem_pestat] mean and std.dev: (479.90, 416.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2894)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699960 sequences (100000146 bp) in 3.053 CPU sec, 3.287 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 280151, 31, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (451, 1026, 1819)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4555)
[M::mem_pestat] mean and std.dev: (1152.84, 1051.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5923)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 237, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 711)
[M::mem_pestat] mean and std.dev: (261.76, 130.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 895)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (360, 774, 1679)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4317)
[M::mem_pestat] mean and std.dev: (1186.77, 1057.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5636)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 327, 654)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1546)
[M::mem_pestat] mean and std.dev: (399.62, 266.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1992)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700086 sequences (100000072 bp) in 2.424 CPU sec, 2.487 real sec...
[M::mem_process_seqs] Processed 700610 reads in 230.124 CPU sec, 7.424 real sec
sorting block 75, #reads = 1065973 mem = 536884204 peak = 899133440
[M::mem_process_seqs] Processed 700110 reads in 155.572 CPU sec, 4.983 real sec
sorting block 76, #reads = 1066309 mem = 536880457 peak = 899133440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 280054, 37, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 424, 984)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2586)
[M::mem_pestat] mean and std.dev: (616.87, 519.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3387)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 236, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709)
[M::mem_pestat] mean and std.dev: (261.81, 130.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 892)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (956, 1122, 3655)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9053)
[M::mem_pestat] mean and std.dev: (1988.65, 1688.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11752)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 538, 966)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2420)
[M::mem_pestat] mean and std.dev: (614.08, 459.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3147)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699722 sequences (100000170 bp) in 3.122 CPU sec, 3.289 real sec...
[M::process] read 699146 sequences (100000022 bp) in 2.232 CPU sec, 2.241 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 279761, 22, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 312, 1118)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3008)
[M::mem_pestat] mean and std.dev: (585.50, 600.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3953)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 236, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 706)
[M::mem_pestat] mean and std.dev: (261.65, 130.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 888)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (345, 502, 1277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3141)
[M::mem_pestat] mean and std.dev: (918.52, 865.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4380)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 366, 1485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4089)
[M::mem_pestat] mean and std.dev: (708.04, 694.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5391)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699960 reads in 226.092 CPU sec, 7.424 real sec
[M::mem_process_seqs] Processed 700086 reads in 152.984 CPU sec, 4.927 real sec
sorting block 77, #reads = 1065974 mem = 536886669 peak = 899133440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 279719, 19, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (358, 890, 1333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3283)
[M::mem_pestat] mean and std.dev: (933.31, 709.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4258)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 237, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 706)
[M::mem_pestat] mean and std.dev: (261.64, 129.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 888)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 261, 1384)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3724)
[M::mem_pestat] mean and std.dev: (590.67, 574.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4894)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 345, 757)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1831)
[M::mem_pestat] mean and std.dev: (502.51, 419.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2368)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699596 sequences (100000188 bp) in 2.946 CPU sec, 3.114 real sec...
[M::process] read 699150 sequences (100000102 bp) in 1.948 CPU sec, 1.957 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 279978, 31, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 298, 682)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1726)
[M::mem_pestat] mean and std.dev: (386.45, 301.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2248)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 238, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 710)
[M::mem_pestat] mean and std.dev: (262.89, 129.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 893)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (996, 1171, 2250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4758)
[M::mem_pestat] mean and std.dev: (1368.36, 879.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6012)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 260, 1125)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2909)
[M::mem_pestat] mean and std.dev: (535.76, 635.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3801)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699722 reads in 228.062 CPU sec, 7.356 real sec
sorting block 78, #reads = 1064682 mem = 536884049 peak = 899133440
[M::mem_process_seqs] Processed 699146 reads in 150.055 CPU sec, 4.936 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 279482, 16, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 705, 1220)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3344)
[M::mem_pestat] mean and std.dev: (704.22, 730.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4406)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 239, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 716)
[M::mem_pestat] mean and std.dev: (264.02, 131.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 901)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (725, 829, 1623)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3419)
[M::mem_pestat] mean and std.dev: (1020.62, 611.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4317)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 270, 645)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1553)
[M::mem_pestat] mean and std.dev: (416.92, 326.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2007)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698966 sequences (100000074 bp) in 2.914 CPU sec, 3.066 real sec...
[M::process] read 701106 sequences (100000293 bp) in 2.048 CPU sec, 2.064 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 279347, 34, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 487, 1176)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3204)
[M::mem_pestat] mean and std.dev: (685.15, 723.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4218)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 239, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 716)
[M::mem_pestat] mean and std.dev: (264.06, 130.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 901)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 1371, 2152)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5992)
[M::mem_pestat] mean and std.dev: (1552.38, 1463.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7912)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 412, 1136)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3076)
[M::mem_pestat] mean and std.dev: (565.97, 602.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4046)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699596 reads in 226.206 CPU sec, 7.354 real sec
sorting block 79, #reads = 1064683 mem = 536878522 peak = 899133440
[M::mem_process_seqs] Processed 699150 reads in 152.091 CPU sec, 4.992 real sec
sorting block 80, #reads = 1064363 mem = 536877451 peak = 899133440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 279412, 34, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 370, 693)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1657)
[M::mem_pestat] mean and std.dev: (456.31, 310.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2139)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 240, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 722)
[M::mem_pestat] mean and std.dev: (265.43, 132.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 909)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (558, 1107, 2885)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7539)
[M::mem_pestat] mean and std.dev: (1686.38, 1398.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9866)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 444, 1943)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5441)
[M::mem_pestat] mean and std.dev: (1235.47, 1405.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7190)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 711142 sequences (100000119 bp) in 3.100 CPU sec, 3.245 real sec...
[M::process] read 707522 sequences (100000061 bp) in 2.257 CPU sec, 2.274 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 279630, 21, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 411, 1305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3597)
[M::mem_pestat] mean and std.dev: (651.19, 677.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4743)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 707)
[M::mem_pestat] mean and std.dev: (260.11, 129.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 890)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 583, 1622)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4482)
[M::mem_pestat] mean and std.dev: (831.10, 1011.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5912)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 335, 1004)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2624)
[M::mem_pestat] mean and std.dev: (535.24, 500.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3434)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698966 reads in 229.019 CPU sec, 7.421 real sec
[M::mem_process_seqs] Processed 701106 reads in 159.086 CPU sec, 5.078 real sec
sorting block 81, #reads = 1063471 mem = 536879657 peak = 899133440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 283703, 23, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 640, 1472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3976)
[M::mem_pestat] mean and std.dev: (767.08, 662.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5228)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 209, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 607)
[M::mem_pestat] mean and std.dev: (231.45, 112.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 761)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (442, 642, 1793)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4495)
[M::mem_pestat] mean and std.dev: (889.62, 809.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5846)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 457, 1218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3190)
[M::mem_pestat] mean and std.dev: (758.33, 700.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4176)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706470 sequences (100000073 bp) in 3.085 CPU sec, 3.251 real sec...
[M::process] read 706082 sequences (100000294 bp) in 2.328 CPU sec, 2.335 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 283156, 27, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 332, 947)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2395)
[M::mem_pestat] mean and std.dev: (584.15, 592.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3119)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 217, 314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 644)
[M::mem_pestat] mean and std.dev: (241.31, 118.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 809)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (72, 256, 930)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2646)
[M::mem_pestat] mean and std.dev: (384.54, 424.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3504)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (301, 459, 1921)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5161)
[M::mem_pestat] mean and std.dev: (1123.03, 1217.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6781)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 711142 reads in 252.501 CPU sec, 8.060 real sec
sorting block 82, #reads = 1061694 mem = 536877543 peak = 899133440
[M::mem_process_seqs] Processed 707522 reads in 169.318 CPU sec, 5.537 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 282408, 31, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 293, 702)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1754)
[M::mem_pestat] mean and std.dev: (449.18, 403.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2280)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 220, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 654)
[M::mem_pestat] mean and std.dev: (243.76, 120.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 822)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (366, 843, 1295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3153)
[M::mem_pestat] mean and std.dev: (815.21, 724.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4082)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 257, 688)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1682)
[M::mem_pestat] mean and std.dev: (264.97, 170.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2179)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706322 sequences (100000130 bp) in 3.117 CPU sec, 3.326 real sec...
[M::process] read 705204 sequences (100000068 bp) in 2.089 CPU sec, 2.092 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 282396, 24, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 472, 796)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1876)
[M::mem_pestat] mean and std.dev: (524.14, 349.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2416)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 222, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 658)
[M::mem_pestat] mean and std.dev: (245.46, 120.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 827)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 743, 2297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6455)
[M::mem_pestat] mean and std.dev: (1276.13, 1567.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8534)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 600, 1790)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4876)
[M::mem_pestat] mean and std.dev: (1161.10, 1161.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6419)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706470 reads in 245.760 CPU sec, 7.973 real sec
sorting block 83, #reads = 1063767 mem = 536884676 peak = 899133440
[M::mem_process_seqs] Processed 706082 reads in 165.059 CPU sec, 5.299 real sec
sorting block 84, #reads = 1063756 mem = 536880684 peak = 899133440
[M::process] read 704156 sequences (100000105 bp) in 2.945 CPU sec, 3.070 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 282594, 33, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 300, 854)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2146)
[M::mem_pestat] mean and std.dev: (375.86, 268.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2792)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 221, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 658)
[M::mem_pestat] mean and std.dev: (244.96, 120.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 827)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (394, 932, 1675)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4237)
[M::mem_pestat] mean and std.dev: (1265.09, 1208.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6100)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 337, 864)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2198)
[M::mem_pestat] mean and std.dev: (443.96, 361.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2865)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706322 reads in 140.135 CPU sec, 4.651 real sec
[M::process] read 703628 sequences (100000115 bp) in 2.241 CPU sec, 2.352 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 282653, 19, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 358, 1529)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4237)
[M::mem_pestat] mean and std.dev: (923.23, 1143.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5591)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (248.36, 122.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 844)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 463, 1152)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3040)
[M::mem_pestat] mean and std.dev: (668.65, 786.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3984)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 551, 830)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2060)
[M::mem_pestat] mean and std.dev: (628.95, 482.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2675)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703522 sequences (100000166 bp) in 1.884 CPU sec, 1.891 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 281853, 23, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 860, 2552)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7326)
[M::mem_pestat] mean and std.dev: (1264.14, 1253.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9713)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (252.13, 124.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (633, 1025, 1830)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4224)
[M::mem_pestat] mean and std.dev: (994.67, 712.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5421)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 383, 852)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2060)
[M::mem_pestat] mean and std.dev: (505.30, 444.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2664)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 282732, 29, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 559, 1634)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4568)
[M::mem_pestat] mean and std.dev: (950.22, 965.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6035)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 226, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 673)
[M::mem_pestat] mean and std.dev: (250.56, 123.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 846)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (598, 914, 1989)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4771)
[M::mem_pestat] mean and std.dev: (1073.15, 978.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6162)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 337, 857)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2157)
[M::mem_pestat] mean and std.dev: (496.62, 478.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2807)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705204 reads in 350.881 CPU sec, 11.272 real sec
sorting block 85, #reads = 1062979 mem = 536881890 peak = 899133440
[M::mem_process_seqs] Processed 703628 reads in 252.083 CPU sec, 8.150 real sec
[M::mem_process_seqs] Processed 704156 reads in 279.953 CPU sec, 9.256 real sec
sorting block 86, #reads = 1064559 mem = 536881579 peak = 899133440
[M::process] read 703026 sequences (100000003 bp) in 2.822 CPU sec, 2.984 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 281903, 20, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 417, 1102)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2866)
[M::mem_pestat] mean and std.dev: (662.92, 573.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3748)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 228, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (253.01, 125.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 859)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (460, 547, 1531)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3673)
[M::mem_pestat] mean and std.dev: (885.58, 805.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4744)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 330, 845)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2185)
[M::mem_pestat] mean and std.dev: (419.34, 455.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2855)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702468 sequences (100000109 bp) in 2.934 CPU sec, 3.140 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 282028, 19, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 308, 575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1353)
[M::mem_pestat] mean and std.dev: (401.94, 285.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1742)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 230, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (254.42, 125.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (361, 1023, 1614)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4120)
[M::mem_pestat] mean and std.dev: (899.29, 570.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5373)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 356, 570)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1246)
[M::mem_pestat] mean and std.dev: (377.36, 247.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1584)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703522 reads in 239.837 CPU sec, 7.814 real sec
sorting block 87, #reads = 1066505 mem = 536879246 peak = 899133440
[M::process] read 703680 sequences (100000118 bp) in 2.220 CPU sec, 2.249 real sec...
[M::mem_process_seqs] Processed 703026 reads in 160.946 CPU sec, 5.344 real sec
sorting block 88, #reads = 1064573 mem = 536879481 peak = 899133440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 280753, 19, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 245, 695)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1727)
[M::mem_pestat] mean and std.dev: (356.40, 280.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2243)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 231, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (256.25, 127.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 876)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (306, 352, 1679)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4425)
[M::mem_pestat] mean and std.dev: (867.79, 983.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5798)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (303, 448, 1054)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2556)
[M::mem_pestat] mean and std.dev: (620.77, 473.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3307)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702306 sequences (100000093 bp) in 2.828 CPU sec, 2.990 real sec...
[M::process] read 701230 sequences (100000225 bp) in 1.841 CPU sec, 1.854 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 281510, 40, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 319, 832)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2090)
[M::mem_pestat] mean and std.dev: (386.97, 339.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2719)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 226, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 676)
[M::mem_pestat] mean and std.dev: (251.23, 124.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 850)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (486, 854, 1571)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3741)
[M::mem_pestat] mean and std.dev: (1069.53, 875.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4826)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 383, 766)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1886)
[M::mem_pestat] mean and std.dev: (446.72, 308.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2446)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702468 reads in 239.383 CPU sec, 7.892 real sec
[M::mem_process_seqs] Processed 703680 reads in 161.887 CPU sec, 5.314 real sec
sorting block 89, #reads = 1064258 mem = 536878071 peak = 899133440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 281713, 24, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 544, 841)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2191)
[M::mem_pestat] mean and std.dev: (543.57, 448.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2866)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 232, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697)
[M::mem_pestat] mean and std.dev: (256.90, 127.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 877)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (310, 530, 981)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2323)
[M::mem_pestat] mean and std.dev: (508.55, 355.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2994)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 372, 1150)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2984)
[M::mem_pestat] mean and std.dev: (472.66, 480.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3901)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703104 sequences (100000057 bp) in 3.011 CPU sec, 3.174 real sec...
[M::process] read 700828 sequences (100000001 bp) in 2.277 CPU sec, 2.281 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 280140, 37, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 335, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 947)
[M::mem_pestat] mean and std.dev: (288.51, 145.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1201)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 234, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 704)
[M::mem_pestat] mean and std.dev: (259.36, 129.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 886)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (318, 1127, 1950)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5214)
[M::mem_pestat] mean and std.dev: (1243.06, 975.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6846)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 339, 1128)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2958)
[M::mem_pestat] mean and std.dev: (668.66, 772.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3873)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702306 reads in 228.178 CPU sec, 7.422 real sec
sorting block 90, #reads = 1064762 mem = 536879476 peak = 899133440
[M::mem_process_seqs] Processed 701230 reads in 152.509 CPU sec, 4.949 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 281596, 33, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 273, 923)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2461)
[M::mem_pestat] mean and std.dev: (545.98, 563.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3230)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 228, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (252.95, 125.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 855)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (421, 788, 1722)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4324)
[M::mem_pestat] mean and std.dev: (1082.42, 863.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5625)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (258, 652, 1740)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4704)
[M::mem_pestat] mean and std.dev: (1144.00, 1228.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6186)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701086 sequences (100000115 bp) in 2.878 CPU sec, 3.023 real sec...
[M::process] read 701174 sequences (100000035 bp) in 2.043 CPU sec, 2.069 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 280183, 31, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 292, 629)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1513)
[M::mem_pestat] mean and std.dev: (407.68, 311.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1955)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 710)
[M::mem_pestat] mean and std.dev: (261.34, 131.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 894)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (410, 1342, 2408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6404)
[M::mem_pestat] mean and std.dev: (1471.68, 1167.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8402)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 431, 1259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3333)
[M::mem_pestat] mean and std.dev: (756.22, 768.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4370)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703104 reads in 222.133 CPU sec, 7.172 real sec
sorting block 91, #reads = 1065186 mem = 536886187 peak = 899133440
[M::mem_process_seqs] Processed 700828 reads in 154.894 CPU sec, 4.958 real sec
sorting block 92, #reads = 1064921 mem = 536877844 peak = 899133440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 280309, 27, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 385, 1226)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3248)
[M::mem_pestat] mean and std.dev: (633.36, 603.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4259)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 234, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 710)
[M::mem_pestat] mean and std.dev: (260.87, 131.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 894)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (505, 1165, 2293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5869)
[M::mem_pestat] mean and std.dev: (1456.56, 1295.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7657)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (263, 425, 949)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2321)
[M::mem_pestat] mean and std.dev: (473.48, 322.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3007)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699806 sequences (100000153 bp) in 2.890 CPU sec, 3.032 real sec...
[M::process] read 699640 sequences (100000015 bp) in 2.146 CPU sec, 2.155 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 280594, 21, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (294, 1164, 2339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6429)
[M::mem_pestat] mean and std.dev: (1440.09, 1394.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8474)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 234, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 713)
[M::mem_pestat] mean and std.dev: (260.88, 131.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 898)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 461, 1939)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5533)
[M::mem_pestat] mean and std.dev: (924.70, 1082.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7330)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 494, 972)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2594)
[M::mem_pestat] mean and std.dev: (551.83, 476.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3405)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701086 reads in 225.605 CPU sec, 7.196 real sec
[M::mem_process_seqs] Processed 701174 reads in 154.937 CPU sec, 4.958 real sec
sorting block 93, #reads = 1064621 mem = 536875980 peak = 899133440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 280205, 42, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 382, 1477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3965)
[M::mem_pestat] mean and std.dev: (723.50, 815.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5209)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 237, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 715)
[M::mem_pestat] mean and std.dev: (262.74, 131.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 900)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (764, 1930, 3516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9020)
[M::mem_pestat] mean and std.dev: (2094.84, 2031.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11772)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 320, 1439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3871)
[M::mem_pestat] mean and std.dev: (790.26, 903.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5087)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699604 sequences (100000148 bp) in 3.077 CPU sec, 3.244 real sec...
[M::process] read 702900 sequences (100000173 bp) in 2.016 CPU sec, 2.030 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 279254, 33, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 286, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 988)
[M::mem_pestat] mean and std.dev: (312.22, 207.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1263)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 238, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 721)
[M::mem_pestat] mean and std.dev: (264.10, 132.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 908)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (417, 766, 3835)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10671)
[M::mem_pestat] mean and std.dev: (1808.52, 1931.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14089)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 480, 1095)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2779)
[M::mem_pestat] mean and std.dev: (565.43, 439.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3621)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699806 reads in 233.475 CPU sec, 7.473 real sec
sorting block 94, #reads = 1066466 mem = 536881960 peak = 899133440
[M::mem_process_seqs] Processed 699640 reads in 161.849 CPU sec, 5.300 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 279302, 14, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 540, 870)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2228)
[M::mem_pestat] mean and std.dev: (536.89, 375.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2907)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 238, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 721)
[M::mem_pestat] mean and std.dev: (264.55, 133.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 908)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (365, 691, 911)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2003)
[M::mem_pestat] mean and std.dev: (677.86, 440.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2549)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 520, 1013)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2573)
[M::mem_pestat] mean and std.dev: (622.67, 546.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3353)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706358 sequences (100000254 bp) in 3.082 CPU sec, 3.217 real sec...
[M::process] read 704596 sequences (100000116 bp) in 2.004 CPU sec, 2.006 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 280791, 28, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 432, 1405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3889)
[M::mem_pestat] mean and std.dev: (771.91, 796.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5131)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 229, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (254.69, 127.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 867)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (340, 1176, 3234)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9022)
[M::mem_pestat] mean and std.dev: (1732.64, 1712.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11916)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (265, 559, 1840)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4990)
[M::mem_pestat] mean and std.dev: (1018.22, 1233.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6565)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699604 reads in 248.220 CPU sec, 8.021 real sec
sorting block 95, #reads = 1061733 mem = 536875736 peak = 899133440
[M::mem_process_seqs] Processed 702900 reads in 176.745 CPU sec, 5.664 real sec
sorting block 96, #reads = 1055472 mem = 536876412 peak = 899133440
[M::process] read 703872 sequences (100000201 bp) in 2.701 CPU sec, 2.830 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 282637, 15, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 244, 996)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2664)
[M::mem_pestat] mean and std.dev: (476.41, 474.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3498)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 221, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 657)
[M::mem_pestat] mean and std.dev: (244.93, 121.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 826)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (357, 673, 3017)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8337)
[M::mem_pestat] mean and std.dev: (1357.07, 1158.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10997)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 274, 1148)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3128)
[M::mem_pestat] mean and std.dev: (495.57, 552.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4118)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702954 sequences (100000209 bp) in 1.775 CPU sec, 1.784 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281545, 12, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 1042, 1559)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4213)
[M::mem_pestat] mean and std.dev: (846.88, 800.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5540)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 225, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (248.98, 123.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 844)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (418, 3070, 5194)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 14746)
[M::mem_pestat] mean and std.dev: (2456.75, 2235.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 19522)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 241, 515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1201)
[M::mem_pestat] mean and std.dev: (359.90, 292.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1544)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 282137, 26, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 316, 675)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1729)
[M::mem_pestat] mean and std.dev: (427.70, 407.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2256)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (251.16, 124.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (699, 1822, 2083)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4851)
[M::mem_pestat] mean and std.dev: (1564.83, 999.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6235)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 419, 1110)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2890)
[M::mem_pestat] mean and std.dev: (708.80, 752.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3780)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706358 reads in 316.190 CPU sec, 10.254 real sec
[M::mem_process_seqs] Processed 704596 reads in 237.330 CPU sec, 7.620 real sec
[M::mem_process_seqs] Processed 703872 reads in 263.325 CPU sec, 8.474 real sec
sorting block 97, #reads = 1065549 mem = 536878775 peak = 899133440
[M::process] read 702308 sequences (100000150 bp) in 2.782 CPU sec, 2.955 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 281758, 24, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 424, 1188)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3124)
[M::mem_pestat] mean and std.dev: (633.56, 554.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4092)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 229, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (254.02, 126.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 867)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (978, 1021, 3920)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9804)
[M::mem_pestat] mean and std.dev: (2145.08, 2269.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12746)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 335, 624)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1374)
[M::mem_pestat] mean and std.dev: (374.13, 251.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1749)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 98, #reads = 1068021 mem = 536879753 peak = 899133440
[M::process] read 702356 sequences (100000111 bp) in 2.897 CPU sec, 3.061 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 281276, 19, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 273, 399)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 855)
[M::mem_pestat] mean and std.dev: (285.19, 169.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1083)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 231, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (255.99, 127.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 876)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (618, 960, 2351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5817)
[M::mem_pestat] mean and std.dev: (1357.26, 1196.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7550)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (258, 602, 1498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3978)
[M::mem_pestat] mean and std.dev: (811.48, 757.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5218)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702954 reads in 206.804 CPU sec, 6.617 real sec
[M::mem_process_seqs] Processed 702308 reads in 140.419 CPU sec, 4.434 real sec
[M::process] read 702014 sequences (100000165 bp) in 2.707 CPU sec, 2.824 real sec...
sorting block 99, #reads = 1068513 mem = 536880277 peak = 899133440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 281583, 29, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 295, 857)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2121)
[M::mem_pestat] mean and std.dev: (461.29, 353.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2753)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 231, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (256.60, 128.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 876)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (520, 687, 2384)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6112)
[M::mem_pestat] mean and std.dev: (1207.15, 1171.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7976)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 517, 1170)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3100)
[M::mem_pestat] mean and std.dev: (616.15, 559.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4065)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701540 sequences (100000121 bp) in 3.176 CPU sec, 3.421 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281681, 26, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 491, 902)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2264)
[M::mem_pestat] mean and std.dev: (491.56, 401.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2945)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 232, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 702)
[M::mem_pestat] mean and std.dev: (257.46, 128.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 884)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (579, 1275, 2406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6060)
[M::mem_pestat] mean and std.dev: (1324.00, 942.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7887)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 749, 3790)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10910)
[M::mem_pestat] mean and std.dev: (2180.22, 2562.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14470)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701608 sequences (100000068 bp) in 1.967 CPU sec, 1.972 real sec...
[M::mem_process_seqs] Processed 702356 reads in 214.389 CPU sec, 6.823 real sec
[M::mem_process_seqs] Processed 702014 reads in 144.463 CPU sec, 4.586 real sec
sorting block 100, #reads = 1070325 mem = 536883508 peak = 899133440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 281532, 22, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 322, 865)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2253)
[M::mem_pestat] mean and std.dev: (677.83, 761.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3724)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 233, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 703)
[M::mem_pestat] mean and std.dev: (258.94, 129.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 885)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (482, 978, 2050)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5186)
[M::mem_pestat] mean and std.dev: (1248.32, 1074.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6754)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 1032, 2525)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7207)
[M::mem_pestat] mean and std.dev: (1160.87, 1318.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9548)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701938 sequences (100000243 bp) in 2.816 CPU sec, 2.961 real sec...
[M::process] read 701308 sequences (100000297 bp) in 1.850 CPU sec, 1.850 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 281215, 34, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 387, 878)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2180)
[M::mem_pestat] mean and std.dev: (601.24, 605.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3022)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 234, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 703)
[M::mem_pestat] mean and std.dev: (258.31, 128.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 885)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (349, 945, 1916)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5050)
[M::mem_pestat] mean and std.dev: (1191.38, 1129.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6617)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (294, 417, 1117)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2763)
[M::mem_pestat] mean and std.dev: (631.86, 609.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3586)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701540 reads in 212.285 CPU sec, 6.760 real sec
sorting block 101, #reads = 1070155 mem = 536880454 peak = 899133440
[M::mem_process_seqs] Processed 701608 reads in 148.523 CPU sec, 4.741 real sec
sorting block 102, #reads = 1068190 mem = 536880791 peak = 899133440
[M::process] read 700454 sequences (100000047 bp) in 2.463 CPU sec, 2.574 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 281207, 17, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 431, 1566)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4258)
[M::mem_pestat] mean and std.dev: (1077.14, 1284.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6214)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 233, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (257.53, 128.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 881)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (41, 436, 1358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3992)
[M::mem_pestat] mean and std.dev: (491.87, 473.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5309)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (264, 820, 1488)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3936)
[M::mem_pestat] mean and std.dev: (904.40, 823.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5160)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700844 sequences (100000270 bp) in 2.192 CPU sec, 2.199 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 281365, 27, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 509, 2118)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5918)
[M::mem_pestat] mean and std.dev: (1282.68, 1504.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7818)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 234, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 707)
[M::mem_pestat] mean and std.dev: (259.45, 129.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 890)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (850, 1267, 2888)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6964)
[M::mem_pestat] mean and std.dev: (1654.15, 1096.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9002)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (290, 590, 1225)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3095)
[M::mem_pestat] mean and std.dev: (668.96, 454.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4030)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701938 reads in 219.181 CPU sec, 6.990 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 280241, 30, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 331, 1141)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3001)
[M::mem_pestat] mean and std.dev: (645.54, 634.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3931)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 237, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 706)
[M::mem_pestat] mean and std.dev: (260.51, 128.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 888)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (417, 854, 1866)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4764)
[M::mem_pestat] mean and std.dev: (895.56, 891.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6213)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 469, 1793)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5001)
[M::mem_pestat] mean and std.dev: (860.59, 926.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6605)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700636 sequences (100000064 bp) in 2.306 CPU sec, 2.309 real sec...
[M::mem_process_seqs] Processed 701308 reads in 243.077 CPU sec, 7.718 real sec
sorting block 103, #reads = 1067130 mem = 536880891 peak = 899133440
[M::mem_process_seqs] Processed 700454 reads in 274.233 CPU sec, 8.741 real sec
sorting block 104, #reads = 1067291 mem = 536882010 peak = 899133440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 280978, 33, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 287, 549)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1321)
[M::mem_pestat] mean and std.dev: (282.16, 223.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1707)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 237, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 717)
[M::mem_pestat] mean and std.dev: (261.79, 130.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 903)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (532, 870, 2466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6334)
[M::mem_pestat] mean and std.dev: (1440.62, 1220.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8268)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 391, 1006)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2604)
[M::mem_pestat] mean and std.dev: (506.74, 415.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3403)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700066 sequences (100000249 bp) in 2.828 CPU sec, 2.999 real sec...
[M::process] read 700092 sequences (100000225 bp) in 1.844 CPU sec, 1.853 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 280327, 41, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 295, 488)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1186)
[M::mem_pestat] mean and std.dev: (298.06, 221.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1535)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 236, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 711)
[M::mem_pestat] mean and std.dev: (260.95, 130.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 895)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (125, 739, 2169)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6257)
[M::mem_pestat] mean and std.dev: (1144.90, 1379.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8301)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 277, 653)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1621)
[M::mem_pestat] mean and std.dev: (363.27, 337.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2105)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700844 reads in 216.956 CPU sec, 6.919 real sec
[M::mem_process_seqs] Processed 700636 reads in 150.357 CPU sec, 4.818 real sec
sorting block 105, #reads = 1067036 mem = 536880481 peak = 899133440
[M::process] read 700020 sequences (100000067 bp) in 2.912 CPU sec, 3.075 real sec...
[M::process] read 699854 sequences (100000131 bp) in 1.939 CPU sec, 1.943 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 279750, 23, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 423, 1222)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3268)
[M::mem_pestat] mean and std.dev: (629.96, 588.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4291)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 237, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709)
[M::mem_pestat] mean and std.dev: (261.66, 130.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 892)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 438, 2526)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7194)
[M::mem_pestat] mean and std.dev: (1506.04, 1734.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9528)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (289, 647, 1708)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4546)
[M::mem_pestat] mean and std.dev: (1014.13, 961.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5965)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700092 reads in 121.839 CPU sec, 3.872 real sec
sorting block 106, #reads = 1065775 mem = 536878708 peak = 899133440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 279973, 15, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 329, 843)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2167)
[M::mem_pestat] mean and std.dev: (498.60, 475.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2829)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 237, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 715)
[M::mem_pestat] mean and std.dev: (262.60, 131.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 900)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (686, 1401, 1442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2954)
[M::mem_pestat] mean and std.dev: (980.36, 639.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3710)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 675, 1432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3814)
[M::mem_pestat] mean and std.dev: (853.89, 822.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5005)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 279663, 32, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 368, 649)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1569)
[M::mem_pestat] mean and std.dev: (413.08, 332.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2029)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 237, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 715)
[M::mem_pestat] mean and std.dev: (262.85, 131.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 900)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (405, 672, 2032)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5286)
[M::mem_pestat] mean and std.dev: (1085.00, 936.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6913)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 452, 2062)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5734)
[M::mem_pestat] mean and std.dev: (1246.62, 1554.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7570)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700142 sequences (100000000 bp) in 2.265 CPU sec, 2.272 real sec...
[M::mem_process_seqs] Processed 700066 reads in 340.328 CPU sec, 10.825 real sec
[M::mem_process_seqs] Processed 700020 reads in 178.742 CPU sec, 5.734 real sec
sorting block 107, #reads = 1065843 mem = 536880791 peak = 899133440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 279820, 20, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 434, 2818)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8004)
[M::mem_pestat] mean and std.dev: (1440.85, 1761.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10597)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 237, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709)
[M::mem_pestat] mean and std.dev: (262.10, 130.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 892)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 1163, 1958)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5568)
[M::mem_pestat] mean and std.dev: (1224.11, 1296.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7373)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 308, 533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1187)
[M::mem_pestat] mean and std.dev: (354.56, 235.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1514)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699968 sequences (100000299 bp) in 3.127 CPU sec, 3.326 real sec...
[M::process] read 700806 sequences (100000000 bp) in 1.956 CPU sec, 1.957 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 279955, 43, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 356, 1330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3618)
[M::mem_pestat] mean and std.dev: (488.06, 467.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4762)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 237, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 712)
[M::mem_pestat] mean and std.dev: (262.36, 131.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 896)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (269, 1027, 1977)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5393)
[M::mem_pestat] mean and std.dev: (1309.91, 1315.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7101)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 461, 2202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6188)
[M::mem_pestat] mean and std.dev: (1104.51, 1131.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8181)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699854 reads in 231.256 CPU sec, 7.638 real sec
[M::mem_process_seqs] Processed 700142 reads in 155.855 CPU sec, 4.982 real sec
sorting block 108, #reads = 1064636 mem = 536883519 peak = 899133440
[M::process] read 699980 sequences (100000117 bp) in 2.752 CPU sec, 2.926 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 279610, 30, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 353, 632)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1504)
[M::mem_pestat] mean and std.dev: (328.60, 235.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1940)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 237, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709)
[M::mem_pestat] mean and std.dev: (262.25, 130.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 892)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (290, 661, 1848)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4964)
[M::mem_pestat] mean and std.dev: (1079.59, 1045.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6522)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 661, 1507)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4067)
[M::mem_pestat] mean and std.dev: (831.35, 729.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5347)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699934 sequences (100000191 bp) in 1.897 CPU sec, 1.954 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 279911, 40, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 299, 779)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1931)
[M::mem_pestat] mean and std.dev: (426.06, 395.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2507)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 710)
[M::mem_pestat] mean and std.dev: (260.63, 130.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 894)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 542, 1340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3644)
[M::mem_pestat] mean and std.dev: (701.19, 612.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4796)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 360, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 956)
[M::mem_pestat] mean and std.dev: (303.06, 165.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1209)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699968 reads in 230.372 CPU sec, 7.432 real sec
sorting block 109, #reads = 1064687 mem = 536883654 peak = 899133440
[M::mem_process_seqs] Processed 700806 reads in 157.499 CPU sec, 5.041 real sec
sorting block 110, #reads = 1063833 mem = 536877546 peak = 899133440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 279591, 27, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 571, 984)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2508)
[M::mem_pestat] mean and std.dev: (627.30, 499.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3270)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 237, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709)
[M::mem_pestat] mean and std.dev: (261.83, 130.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 892)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (368, 1107, 5649)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 16211)
[M::mem_pestat] mean and std.dev: (2744.22, 3163.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 21492)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 570, 1397)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3715)
[M::mem_pestat] mean and std.dev: (982.24, 991.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4950)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707458 sequences (100000092 bp) in 2.941 CPU sec, 3.148 real sec...
[M::process] read 709978 sequences (100000072 bp) in 2.317 CPU sec, 2.332 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 279599, 18, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 600, 2313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6491)
[M::mem_pestat] mean and std.dev: (1272.76, 1398.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8580)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 238, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 715)
[M::mem_pestat] mean and std.dev: (262.78, 131.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 900)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (593, 1466, 2327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5795)
[M::mem_pestat] mean and std.dev: (1683.28, 1140.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7529)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 361, 1148)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3042)
[M::mem_pestat] mean and std.dev: (600.34, 694.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3989)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699980 reads in 234.629 CPU sec, 7.588 real sec
[M::mem_process_seqs] Processed 699934 reads in 168.934 CPU sec, 5.415 real sec
sorting block 111, #reads = 1062874 mem = 536880133 peak = 899133440
[M::process] read 707604 sequences (100000232 bp) in 2.830 CPU sec, 2.964 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 282284, 36, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 375, 970)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2548)
[M::mem_pestat] mean and std.dev: (487.80, 437.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3337)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 218, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 650)
[M::mem_pestat] mean and std.dev: (242.60, 120.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 817)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (507, 1324, 3317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8937)
[M::mem_pestat] mean and std.dev: (1917.58, 1888.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11747)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 397, 1382)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3698)
[M::mem_pestat] mean and std.dev: (755.80, 680.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4856)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706412 sequences (100000220 bp) in 2.193 CPU sec, 2.209 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 283062, 23, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 383, 1209)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3225)
[M::mem_pestat] mean and std.dev: (653.94, 600.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4233)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 218, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 647)
[M::mem_pestat] mean and std.dev: (241.83, 119.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 813)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (401, 819, 1730)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4388)
[M::mem_pestat] mean and std.dev: (1096.41, 980.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5717)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 270, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 988)
[M::mem_pestat] mean and std.dev: (272.12, 128.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1246)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 283876, 27, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 318, 1234)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3298)
[M::mem_pestat] mean and std.dev: (685.83, 778.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4330)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 213, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 626)
[M::mem_pestat] mean and std.dev: (235.64, 115.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 786)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (408, 870, 2490)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6654)
[M::mem_pestat] mean and std.dev: (1384.62, 1438.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8736)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 417, 994)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2468)
[M::mem_pestat] mean and std.dev: (630.41, 567.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3205)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707458 reads in 358.337 CPU sec, 11.460 real sec
sorting block 112, #reads = 1053188 mem = 536879635 peak = 899133440
[M::mem_process_seqs] Processed 707604 reads in 274.902 CPU sec, 8.834 real sec
[M::mem_process_seqs] Processed 709978 reads in 307.577 CPU sec, 9.894 real sec
[M::process] read 705108 sequences (100000155 bp) in 2.974 CPU sec, 3.461 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 282211, 24, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 327, 1256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3416)
[M::mem_pestat] mean and std.dev: (620.96, 620.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4496)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 221, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 658)
[M::mem_pestat] mean and std.dev: (244.82, 120.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 827)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 750, 1359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3723)
[M::mem_pestat] mean and std.dev: (788.25, 692.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4905)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (287, 511, 1249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3173)
[M::mem_pestat] mean and std.dev: (686.59, 546.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4135)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 113, #reads = 1062765 mem = 536880477 peak = 899133440
[M::process] read 704904 sequences (100000156 bp) in 2.617 CPU sec, 2.753 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 282067, 30, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 268, 983)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2635)
[M::mem_pestat] mean and std.dev: (540.91, 592.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3461)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 224, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (247.70, 121.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 837)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (427, 604, 2082)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5392)
[M::mem_pestat] mean and std.dev: (1199.60, 1155.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7047)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 370, 1132)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2984)
[M::mem_pestat] mean and std.dev: (564.88, 523.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3910)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704572 sequences (100000111 bp) in 2.137 CPU sec, 2.150 real sec...
[M::mem_process_seqs] Processed 706412 reads in 243.610 CPU sec, 7.787 real sec
sorting block 114, #reads = 1062855 mem = 536879160 peak = 899133440
[M::process] read 703628 sequences (100000048 bp) in 2.866 CPU sec, 2.897 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 282077, 24, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 285, 766)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1912)
[M::mem_pestat] mean and std.dev: (392.58, 310.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2485)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (248.77, 123.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 844)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (571, 1281, 2978)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7792)
[M::mem_pestat] mean and std.dev: (1992.75, 2105.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10416)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 331, 871)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2145)
[M::mem_pestat] mean and std.dev: (515.97, 410.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2782)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704904 reads in 145.111 CPU sec, 4.600 real sec
[M::mem_process_seqs] Processed 705108 reads in 360.378 CPU sec, 11.487 real sec
sorting block 115, #reads = 1061634 mem = 536878867 peak = 899133440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 282053, 26, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 368, 861)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2205)
[M::mem_pestat] mean and std.dev: (480.00, 424.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2877)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 225, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 675)
[M::mem_pestat] mean and std.dev: (249.91, 123.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 849)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (625, 1163, 1407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2971)
[M::mem_pestat] mean and std.dev: (1003.48, 567.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3753)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 265, 761)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1981)
[M::mem_pestat] mean and std.dev: (380.30, 369.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2591)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703066 sequences (100000149 bp) in 3.000 CPU sec, 3.200 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 281823, 28, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 527, 1620)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4562)
[M::mem_pestat] mean and std.dev: (811.50, 851.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6033)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (252.70, 125.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 862)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (473, 891, 2329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6041)
[M::mem_pestat] mean and std.dev: (1176.00, 1205.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7897)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 308, 858)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2194)
[M::mem_pestat] mean and std.dev: (389.37, 355.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2862)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703462 sequences (100000068 bp) in 1.992 CPU sec, 2.001 real sec...
[M::mem_process_seqs] Processed 704572 reads in 265.182 CPU sec, 8.471 real sec
[M::mem_process_seqs] Processed 703628 reads in 160.856 CPU sec, 5.126 real sec
sorting block 116, #reads = 1064455 mem = 536878012 peak = 899133440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 281596, 32, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 371, 1479)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4131)
[M::mem_pestat] mean and std.dev: (630.47, 674.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5457)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 229, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (254.51, 126.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 867)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (532, 633, 1088)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2200)
[M::mem_pestat] mean and std.dev: (681.41, 405.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2756)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (268, 437, 1209)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3091)
[M::mem_pestat] mean and std.dev: (753.15, 698.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4032)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701656 sequences (100000068 bp) in 2.879 CPU sec, 3.004 real sec...
[M::process] read 700166 sequences (100000263 bp) in 2.107 CPU sec, 2.112 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 281147, 23, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 400, 1570)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4306)
[M::mem_pestat] mean and std.dev: (799.78, 885.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5674)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 228, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (252.31, 125.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 855)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (354, 892, 1487)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3753)
[M::mem_pestat] mean and std.dev: (906.29, 836.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4886)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 348, 705)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1741)
[M::mem_pestat] mean and std.dev: (394.02, 295.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2259)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703066 reads in 233.952 CPU sec, 7.465 real sec
sorting block 117, #reads = 1066066 mem = 536878142 peak = 899133440
[M::mem_process_seqs] Processed 703462 reads in 160.892 CPU sec, 5.146 real sec
sorting block 118, #reads = 1065042 mem = 536878776 peak = 899133440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 280162, 20, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 368, 965)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2501)
[M::mem_pestat] mean and std.dev: (517.25, 396.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3269)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 232, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (256.54, 126.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 869)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (460, 816, 5542)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 15706)
[M::mem_pestat] mean and std.dev: (2412.25, 2901.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 20788)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 382, 1012)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2606)
[M::mem_pestat] mean and std.dev: (640.51, 607.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3403)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701558 sequences (100000289 bp) in 3.113 CPU sec, 3.286 real sec...
[M::process] read 701180 sequences (100000067 bp) in 1.830 CPU sec, 1.840 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 279361, 37, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 231, 1427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3949)
[M::mem_pestat] mean and std.dev: (643.59, 831.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5210)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 237, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 711)
[M::mem_pestat] mean and std.dev: (261.26, 129.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 895)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (350, 994, 1731)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4493)
[M::mem_pestat] mean and std.dev: (1100.92, 980.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5874)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 290, 1232)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3386)
[M::mem_pestat] mean and std.dev: (536.12, 571.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4463)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701656 reads in 231.427 CPU sec, 7.394 real sec
[M::mem_process_seqs] Processed 700166 reads in 157.498 CPU sec, 5.039 real sec
sorting block 119, #reads = 1062380 mem = 536882714 peak = 899133440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 280027, 41, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 364, 1259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3311)
[M::mem_pestat] mean and std.dev: (750.68, 814.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4337)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 232, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (256.56, 126.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 869)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (253, 970, 1720)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4654)
[M::mem_pestat] mean and std.dev: (1072.55, 1132.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6121)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 415, 1445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3901)
[M::mem_pestat] mean and std.dev: (838.97, 753.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5129)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700440 sequences (100000120 bp) in 3.157 CPU sec, 3.317 real sec...
[M::process] read 700686 sequences (100000267 bp) in 2.060 CPU sec, 2.067 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 279869, 38, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 320, 1191)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3233)
[M::mem_pestat] mean and std.dev: (532.60, 474.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4254)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 233, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (257.11, 126.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 691, 1202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3320)
[M::mem_pestat] mean and std.dev: (640.88, 642.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4379)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 402, 1484)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3956)
[M::mem_pestat] mean and std.dev: (813.73, 917.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5192)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701558 reads in 227.558 CPU sec, 7.255 real sec
sorting block 120, #reads = 1061118 mem = 536877772 peak = 899133440
[M::mem_process_seqs] Processed 701180 reads in 154.427 CPU sec, 4.913 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 279783, 25, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 402, 704)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1756)
[M::mem_pestat] mean and std.dev: (386.67, 303.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2282)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 235, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (259.02, 127.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (552, 678, 1952)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4752)
[M::mem_pestat] mean and std.dev: (1340.40, 1288.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6495)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 344, 1321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3585)
[M::mem_pestat] mean and std.dev: (667.00, 702.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4717)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700882 sequences (100000295 bp) in 2.824 CPU sec, 2.968 real sec...
[M::process] read 700760 sequences (100000032 bp) in 2.139 CPU sec, 2.142 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 279898, 20, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (285, 538, 1997)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5421)
[M::mem_pestat] mean and std.dev: (1034.49, 1020.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7133)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 235, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (259.42, 128.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 956, 1963)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5393)
[M::mem_pestat] mean and std.dev: (1243.50, 1031.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7108)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 312, 901)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2267)
[M::mem_pestat] mean and std.dev: (512.95, 458.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2950)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700440 reads in 220.295 CPU sec, 7.013 real sec
sorting block 121, #reads = 1063319 mem = 536876487 peak = 899133440
[M::mem_process_seqs] Processed 700686 reads in 152.159 CPU sec, 4.850 real sec
sorting block 122, #reads = 1065601 mem = 536876765 peak = 899133440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 280287, 18, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 319, 808)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2056)
[M::mem_pestat] mean and std.dev: (371.02, 313.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2680)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 234, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (258.16, 127.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 878)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (390, 694, 1047)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2361)
[M::mem_pestat] mean and std.dev: (692.61, 460.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3018)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 377, 1691)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4667)
[M::mem_pestat] mean and std.dev: (890.73, 1037.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6155)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700144 sequences (100000236 bp) in 3.044 CPU sec, 3.178 real sec...
[M::process] read 700670 sequences (100000271 bp) in 2.032 CPU sec, 2.042 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 280059, 29, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 223, 680)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1716)
[M::mem_pestat] mean and std.dev: (443.51, 477.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2353)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 234, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (258.89, 128.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 878)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (339, 636, 1348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3366)
[M::mem_pestat] mean and std.dev: (852.70, 743.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4375)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 434, 825)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1967)
[M::mem_pestat] mean and std.dev: (540.63, 363.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2538)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700882 reads in 214.919 CPU sec, 6.838 real sec
[M::mem_process_seqs] Processed 700760 reads in 146.849 CPU sec, 4.674 real sec
sorting block 123, #reads = 1066377 mem = 536885848 peak = 899133440
[M::process] read 699112 sequences (100000289 bp) in 2.996 CPU sec, 3.138 real sec...
[M::process] read 699820 sequences (100000229 bp) in 2.096 CPU sec, 2.115 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 280184, 16, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 306, 1838)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5070)
[M::mem_pestat] mean and std.dev: (905.19, 1111.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6686)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 235, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 705)
[M::mem_pestat] mean and std.dev: (260.17, 129.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 887)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 597, 2579)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7331)
[M::mem_pestat] mean and std.dev: (1358.94, 1737.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9707)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 354, 841)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2187)
[M::mem_pestat] mean and std.dev: (474.23, 402.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2860)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700670 reads in 131.645 CPU sec, 4.204 real sec
sorting block 124, #reads = 1065392 mem = 536885183 peak = 899133440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 279630, 27, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 296, 979)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2487)
[M::mem_pestat] mean and std.dev: (518.89, 430.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3241)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 235, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 702)
[M::mem_pestat] mean and std.dev: (260.11, 129.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 883)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (507, 967, 1946)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4824)
[M::mem_pestat] mean and std.dev: (1365.48, 1280.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6488)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 371, 1082)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2780)
[M::mem_pestat] mean and std.dev: (497.50, 412.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3629)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 280363, 15, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 345, 956)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2512)
[M::mem_pestat] mean and std.dev: (511.38, 453.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3290)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 240, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 725)
[M::mem_pestat] mean and std.dev: (265.47, 132.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 913)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (345, 675, 2963)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8199)
[M::mem_pestat] mean and std.dev: (1344.40, 1533.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10817)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 596, 1232)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3252)
[M::mem_pestat] mean and std.dev: (666.62, 600.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4262)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 576116 sequences (82277314 bp) in 2.263 CPU sec, 2.271 real sec...
[M::mem_process_seqs] Processed 700144 reads in 356.629 CPU sec, 11.394 real sec
[M::mem_process_seqs] Processed 699112 reads in 189.243 CPU sec, 6.103 real sec
sorting block 125, #reads = 1063489 mem = 536882936 peak = 899133440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 279676, 27, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 353, 1505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4161)
[M::mem_pestat] mean and std.dev: (785.15, 953.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5489)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 238, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 715)
[M::mem_pestat] mean and std.dev: (263.44, 131.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 900)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (397, 993, 1865)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4801)
[M::mem_pestat] mean and std.dev: (1058.24, 1008.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6269)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 421, 1113)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2921)
[M::mem_pestat] mean and std.dev: (709.00, 716.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3825)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 230173, 22, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 567, 1087)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2811)
[M::mem_pestat] mean and std.dev: (770.05, 625.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3673)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 237, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 711)
[M::mem_pestat] mean and std.dev: (261.67, 130.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 895)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (340, 662, 1099)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2617)
[M::mem_pestat] mean and std.dev: (652.00, 418.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3376)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 623, 870)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2126)
[M::mem_pestat] mean and std.dev: (497.77, 329.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2754)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699820 reads in 206.127 CPU sec, 6.703 real sec
[M::mem_process_seqs] Processed 576116 reads in 135.293 CPU sec, 4.388 real sec
sorting block 126, #reads = 1066094 mem = 536877487 peak = 899133440
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 135121516
overall: 70447398912 mem 24919.735 user 966.981 sys 871.669 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1136_76X-T1-TDNA-1_A23MHWWLT4_1.L007\tPU:L007\tSM:1136_76X-T1-TDNA-1_A23MHWWLT4_1\tLB:1136_76X-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1136_76X-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1136_76X-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 871.700 sec; CPU: 25886.719 sec
sorting block 127, #reads = 728352 mem = 368723501 peak = 899133440
uniq header count 1
merging 128 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31 max 384
algo: util-sort
license: sentieon:util=1
output file size: 7846564284
output reads: 136241500
bam_mem_sort: 128 calls 90.591 user 1.604 sys 92.612 real
bam_write: 128 calls 61.231 user 6.284 sys 76.635 real
execute: 1 calls 52.403 user 4.544 sys 933.615 real
merge_files: 1 calls 52.381 user 4.514 sys 61.025 real
parse_chunk: 2043 calls 96.228 user 27.265 sys 127.825 real
read_chunk: 5533 calls 65.227 user 45.972 sys 784.236 real
sort_block: 1 calls 45.418 user 44.202 sys 755.076 real
write_chunk: 3488 calls 51.839 user 3.977 sys 59.507 real
overall: 3084414976 mem 2242.803 user 132.697 sys 933.633 real
ls: cannot access '*.cram': No such file or directory