cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1136_27F-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 2009.105 CPU sec, 73.914 real sec
[M::process] read 701366 sequences (100000141 bp) in 1.274 CPU sec, 1.280 real sec...
[M::process] read 699404 sequences (100000176 bp) in 1.687 CPU sec, 1.725 real sec...
[M::process] read 698664 sequences (100000154 bp) in 1.612 CPU sec, 1.677 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 292340, 11, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 233, 1073)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2855)
[M::mem_pestat] mean and std.dev: (602.18, 676.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3746)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 707)
[M::mem_pestat] mean and std.dev: (259.38, 129.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 890)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (401, 617, 1192)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2774)
[M::mem_pestat] mean and std.dev: (601.44, 293.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3565)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 333, 736)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1788)
[M::mem_pestat] mean and std.dev: (416.33, 312.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2314)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697828 sequences (100000230 bp) in 1.562 CPU sec, 1.598 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (84, 291705, 24, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 298, 756)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1934)
[M::mem_pestat] mean and std.dev: (436.14, 384.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2523)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 240, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 727)
[M::mem_pestat] mean and std.dev: (264.90, 132.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 916)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (468, 948, 2741)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7287)
[M::mem_pestat] mean and std.dev: (1455.00, 1420.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9560)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 326, 791)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1987)
[M::mem_pestat] mean and std.dev: (485.95, 430.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2585)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701366 reads in 194.401 CPU sec, 6.280 real sec
[M::mem_process_seqs] Processed 699404 reads in 107.075 CPU sec, 3.462 real sec
sorting block 0, #reads = 1090653 mem = 536878756 peak = 589365248
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 291423, 28, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 270, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 994)
[M::mem_pestat] mean and std.dev: (300.30, 153.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1263)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 243, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 738)
[M::mem_pestat] mean and std.dev: (268.41, 134.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 930)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (464, 665, 1393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3251)
[M::mem_pestat] mean and std.dev: (992.46, 868.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4468)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 408, 778)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1850)
[M::mem_pestat] mean and std.dev: (478.39, 353.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2386)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696876 sequences (100000141 bp) in 2.267 CPU sec, 2.443 real sec...
[M::process] read 696544 sequences (100000094 bp) in 1.732 CPU sec, 1.743 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 291279, 28, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 348, 577)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1261)
[M::mem_pestat] mean and std.dev: (364.21, 233.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1603)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 246, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (271.07, 136.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 943)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 1067, 1648)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4470)
[M::mem_pestat] mean and std.dev: (1027.61, 860.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5881)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 309, 519)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1205)
[M::mem_pestat] mean and std.dev: (335.34, 240.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1548)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698664 reads in 165.354 CPU sec, 5.360 real sec
[M::mem_process_seqs] Processed 697828 reads in 106.075 CPU sec, 3.447 real sec
sorting block 1, #reads = 1090529 mem = 536884156 peak = 716767232
[M::process] read 696678 sequences (100000246 bp) in 2.161 CPU sec, 2.275 real sec...
[M::process] read 696250 sequences (100000072 bp) in 1.701 CPU sec, 1.707 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 290569, 24, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 251, 664)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1676)
[M::mem_pestat] mean and std.dev: (384.80, 335.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2182)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 248, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (273.16, 136.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 942)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (258, 415, 838)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1998)
[M::mem_pestat] mean and std.dev: (492.96, 382.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2578)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 235, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1005)
[M::mem_pestat] mean and std.dev: (270.18, 178.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1286)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696544 reads in 93.704 CPU sec, 2.968 real sec
sorting block 2, #reads = 1088619 mem = 536879588 peak = 851877888
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 291021, 23, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 332, 638)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1486)
[M::mem_pestat] mean and std.dev: (360.28, 223.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1910)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (273.19, 136.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 945)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 323, 1641)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4593)
[M::mem_pestat] mean and std.dev: (938.39, 1077.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6069)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 389, 726)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1746)
[M::mem_pestat] mean and std.dev: (452.00, 347.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2256)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 290519, 18, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 311, 496)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1142)
[M::mem_pestat] mean and std.dev: (324.12, 255.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1465)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 246, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 741)
[M::mem_pestat] mean and std.dev: (271.29, 135.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 933)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (88, 193, 607)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1645)
[M::mem_pestat] mean and std.dev: (358.53, 408.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2164)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 301, 411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 839)
[M::mem_pestat] mean and std.dev: (298.06, 170.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1053)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696876 reads in 251.134 CPU sec, 7.997 real sec
[M::process] read 695892 sequences (100000017 bp) in 2.067 CPU sec, 2.116 real sec...
[M::mem_process_seqs] Processed 696678 reads in 122.076 CPU sec, 3.901 real sec
sorting block 3, #reads = 1089457 mem = 536879132 peak = 851877888
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 289964, 27, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 285, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 997)
[M::mem_pestat] mean and std.dev: (287.52, 188.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1276)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 741)
[M::mem_pestat] mean and std.dev: (271.79, 135.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 933)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 566, 2037)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5793)
[M::mem_pestat] mean and std.dev: (901.52, 931.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7671)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 354, 745)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1821)
[M::mem_pestat] mean and std.dev: (428.12, 286.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2359)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694556 sequences (100000106 bp) in 2.613 CPU sec, 2.766 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 290652, 22, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 286, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 982)
[M::mem_pestat] mean and std.dev: (330.65, 196.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1239)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 249, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 746)
[M::mem_pestat] mean and std.dev: (273.65, 135.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 939)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (109, 430, 1698)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4876)
[M::mem_pestat] mean and std.dev: (875.32, 989.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6465)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 254, 551)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1321)
[M::mem_pestat] mean and std.dev: (345.62, 273.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1706)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694034 sequences (100000038 bp) in 1.566 CPU sec, 1.573 real sec...
[M::mem_process_seqs] Processed 696250 reads in 162.169 CPU sec, 5.208 real sec
[M::mem_process_seqs] Processed 695892 reads in 104.622 CPU sec, 3.403 real sec
sorting block 4, #reads = 1087850 mem = 536877840 peak = 851877888
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 289318, 29, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 245, 681)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1719)
[M::mem_pestat] mean and std.dev: (368.08, 315.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2238)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 253, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (276.50, 136.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 945)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (87, 489, 936)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2634)
[M::mem_pestat] mean and std.dev: (592.19, 541.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3483)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 419, 709)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1641)
[M::mem_pestat] mean and std.dev: (430.69, 320.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2107)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693496 sequences (100000161 bp) in 2.195 CPU sec, 2.393 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 289709, 25, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 391, 575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1365)
[M::mem_pestat] mean and std.dev: (330.12, 231.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1760)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 254, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 749)
[M::mem_pestat] mean and std.dev: (276.44, 134.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 942)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (351, 604, 4505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12813)
[M::mem_pestat] mean and std.dev: (1770.04, 2204.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16967)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 312, 486)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1116)
[M::mem_pestat] mean and std.dev: (327.44, 202.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1431)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694556 reads in 162.905 CPU sec, 5.264 real sec
[M::process] read 698338 sequences (100000009 bp) in 1.806 CPU sec, 1.827 real sec...
[M::mem_process_seqs] Processed 694034 reads in 107.073 CPU sec, 3.430 real sec
sorting block 5, #reads = 1088179 mem = 536882592 peak = 851877888
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 289779, 33, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (261, 369, 489)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 945)
[M::mem_pestat] mean and std.dev: (334.14, 130.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1173)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 257, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 762)
[M::mem_pestat] mean and std.dev: (279.91, 137.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 959)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (93, 635, 1453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4173)
[M::mem_pestat] mean and std.dev: (858.38, 927.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5533)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 331, 638)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1438)
[M::mem_pestat] mean and std.dev: (365.42, 211.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1838)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700014 sequences (100000249 bp) in 2.421 CPU sec, 2.783 real sec...
sorting block 6, #reads = 1087327 mem = 536879158 peak = 877924352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 291076, 23, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 316, 1064)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2798)
[M::mem_pestat] mean and std.dev: (523.16, 449.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3665)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 244, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 732)
[M::mem_pestat] mean and std.dev: (267.83, 133.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 922)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (255, 395, 561)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1173)
[M::mem_pestat] mean and std.dev: (370.29, 215.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1479)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 263, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1030)
[M::mem_pestat] mean and std.dev: (300.41, 212.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1319)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 693496 reads in 163.512 CPU sec, 5.439 real sec
[M::mem_process_seqs] Processed 698338 reads in 109.284 CPU sec, 3.576 real sec
[M::process] read 698570 sequences (100000149 bp) in 1.901 CPU sec, 2.000 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 291778, 23, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 278, 541)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1331)
[M::mem_pestat] mean and std.dev: (327.38, 222.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1726)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 240, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 730)
[M::mem_pestat] mean and std.dev: (265.13, 133.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 920)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (358, 772, 1690)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4354)
[M::mem_pestat] mean and std.dev: (855.70, 795.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5686)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 244, 484)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1070)
[M::mem_pestat] mean and std.dev: (337.02, 224.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1363)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 7, #reads = 1086605 mem = 536878154 peak = 877924352
[M::process] read 697798 sequences (100000207 bp) in 2.611 CPU sec, 2.809 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 291231, 12, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 351, 803)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2027)
[M::mem_pestat] mean and std.dev: (387.99, 341.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2639)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 243, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 741)
[M::mem_pestat] mean and std.dev: (269.09, 135.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 934)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (343, 900, 2872)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7930)
[M::mem_pestat] mean and std.dev: (1776.00, 2120.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10459)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 318, 574)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1314)
[M::mem_pestat] mean and std.dev: (384.05, 272.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1684)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700014 reads in 163.668 CPU sec, 5.307 real sec
[M::mem_process_seqs] Processed 698570 reads in 108.580 CPU sec, 3.477 real sec
[M::process] read 697206 sequences (100000293 bp) in 2.006 CPU sec, 2.112 real sec...
sorting block 8, #reads = 1091320 mem = 536877595 peak = 877924352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 290971, 26, 101)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 210, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 919)
[M::mem_pestat] mean and std.dev: (268.04, 172.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1174)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 246, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (272.32, 137.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 951)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 385, 617)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1539)
[M::mem_pestat] mean and std.dev: (431.52, 312.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2000)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 332, 633)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1505)
[M::mem_pestat] mean and std.dev: (389.73, 299.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1941)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696702 sequences (100000139 bp) in 2.603 CPU sec, 3.075 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 290657, 17, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 233, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1100)
[M::mem_pestat] mean and std.dev: (266.96, 185.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1417)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 247, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (273.18, 137.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 952)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 397, 989)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2629)
[M::mem_pestat] mean and std.dev: (553.76, 428.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3449)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 318, 885)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2249)
[M::mem_pestat] mean and std.dev: (437.17, 468.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2931)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697798 reads in 161.927 CPU sec, 5.376 real sec
[M::mem_process_seqs] Processed 697206 reads in 107.773 CPU sec, 3.555 real sec
sorting block 9, #reads = 1090456 mem = 536877565 peak = 877924352
[M::process] read 696998 sequences (100000142 bp) in 2.240 CPU sec, 2.556 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (87, 290500, 24, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 324, 578)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1326)
[M::mem_pestat] mean and std.dev: (369.45, 249.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1700)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (274.47, 138.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 953)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 789, 1890)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5358)
[M::mem_pestat] mean and std.dev: (1044.78, 1138.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7092)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 386, 639)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1535)
[M::mem_pestat] mean and std.dev: (410.00, 287.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1983)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696986 sequences (100000050 bp) in 2.128 CPU sec, 2.440 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 290810, 22, 94)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 283, 672)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1630)
[M::mem_pestat] mean and std.dev: (428.59, 347.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2109)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 741)
[M::mem_pestat] mean and std.dev: (271.44, 135.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 933)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (274, 903, 1829)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4939)
[M::mem_pestat] mean and std.dev: (791.44, 671.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6494)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 320, 757)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1827)
[M::mem_pestat] mean and std.dev: (419.55, 329.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2362)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696702 reads in 167.853 CPU sec, 5.563 real sec
sorting block 10, #reads = 1089595 mem = 536879408 peak = 877924352
[M::mem_process_seqs] Processed 696998 reads in 109.879 CPU sec, 3.613 real sec
[M::process] read 696190 sequences (100000087 bp) in 2.193 CPU sec, 2.479 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 290552, 26, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 265, 956)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2514)
[M::mem_pestat] mean and std.dev: (465.29, 472.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3293)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 246, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 746)
[M::mem_pestat] mean and std.dev: (271.78, 136.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 940)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 447, 759)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1907)
[M::mem_pestat] mean and std.dev: (500.60, 437.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2481)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 291, 641)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1587)
[M::mem_pestat] mean and std.dev: (380.85, 273.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2060)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 11, #reads = 1088863 mem = 536879334 peak = 877924352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 290312, 18, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 258, 529)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1265)
[M::mem_pestat] mean and std.dev: (374.69, 309.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1633)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 248, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 742)
[M::mem_pestat] mean and std.dev: (272.35, 135.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 934)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 441, 1367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3797)
[M::mem_pestat] mean and std.dev: (695.28, 645.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5012)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 241, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (250.52, 132.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695792 sequences (100000162 bp) in 2.513 CPU sec, 2.851 real sec...
[M::mem_process_seqs] Processed 696986 reads in 168.213 CPU sec, 5.618 real sec
[M::mem_process_seqs] Processed 696190 reads in 109.709 CPU sec, 3.665 real sec
[M::process] read 695514 sequences (100000004 bp) in 2.319 CPU sec, 2.612 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 290138, 33, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 321, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 934)
[M::mem_pestat] mean and std.dev: (322.77, 185.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1175)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 249, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 745)
[M::mem_pestat] mean and std.dev: (273.44, 136.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 938)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (548, 1079, 1652)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3860)
[M::mem_pestat] mean and std.dev: (1003.65, 831.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4964)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 337, 530)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1182)
[M::mem_pestat] mean and std.dev: (382.16, 238.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1508)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695792 reads in 93.084 CPU sec, 3.181 real sec
sorting block 12, #reads = 1088779 mem = 536878464 peak = 877924352
[M::process] read 694646 sequences (100000210 bp) in 2.314 CPU sec, 2.585 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 290265, 23, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 286, 611)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1479)
[M::mem_pestat] mean and std.dev: (350.94, 258.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1913)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 251, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 752)
[M::mem_pestat] mean and std.dev: (275.27, 136.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 947)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 282, 914)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2404)
[M::mem_pestat] mean and std.dev: (422.10, 402.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3149)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 284, 818)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2068)
[M::mem_pestat] mean and std.dev: (473.08, 439.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2693)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 13, #reads = 1088182 mem = 536877893 peak = 877924352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (79, 289870, 35, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 221, 290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 546)
[M::mem_pestat] mean and std.dev: (225.28, 96.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 674)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 254, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (277.22, 137.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (92, 533, 965)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2711)
[M::mem_pestat] mean and std.dev: (520.23, 561.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3584)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 412, 1028)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2706)
[M::mem_pestat] mean and std.dev: (566.87, 509.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3545)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695980 sequences (100000024 bp) in 2.535 CPU sec, 2.700 real sec...
[M::mem_process_seqs] Processed 695514 reads in 167.090 CPU sec, 5.576 real sec
[M::mem_process_seqs] Processed 694646 reads in 109.391 CPU sec, 3.567 real sec
[M::process] read 700266 sequences (100000052 bp) in 2.563 CPU sec, 2.732 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 290431, 10, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 306, 866)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2194)
[M::mem_pestat] mean and std.dev: (521.49, 511.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2858)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 250, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (275.28, 137.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 286, 2104)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5876)
[M::mem_pestat] mean and std.dev: (981.40, 1217.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7762)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 280, 510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1142)
[M::mem_pestat] mean and std.dev: (314.32, 182.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1458)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 14, #reads = 1087104 mem = 536878631 peak = 877924352
[M::process] read 698814 sequences (100000073 bp) in 2.296 CPU sec, 2.456 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 292043, 38, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 279, 777)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2041)
[M::mem_pestat] mean and std.dev: (415.04, 412.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2673)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 237, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 714)
[M::mem_pestat] mean and std.dev: (261.57, 130.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 899)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (54, 475, 924)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2664)
[M::mem_pestat] mean and std.dev: (516.00, 524.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3534)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 280, 552)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1310)
[M::mem_pestat] mean and std.dev: (364.67, 267.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1689)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695980 reads in 168.007 CPU sec, 5.412 real sec
[M::mem_process_seqs] Processed 700266 reads in 110.274 CPU sec, 3.502 real sec
[M::process] read 697702 sequences (100000135 bp) in 2.471 CPU sec, 2.604 real sec...
sorting block 15, #reads = 1086924 mem = 536880299 peak = 877924352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 291489, 18, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 305, 731)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1827)
[M::mem_pestat] mean and std.dev: (437.34, 437.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2375)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 242, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 731)
[M::mem_pestat] mean and std.dev: (266.35, 132.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 921)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 536, 934)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2302)
[M::mem_pestat] mean and std.dev: (566.29, 423.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2986)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 255, 822)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2094)
[M::mem_pestat] mean and std.dev: (502.30, 494.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2730)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696792 sequences (100000297 bp) in 2.663 CPU sec, 2.834 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 290845, 25, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (123, 200, 288)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 618)
[M::mem_pestat] mean and std.dev: (196.27, 90.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 783)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 245, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 736)
[M::mem_pestat] mean and std.dev: (269.24, 133.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 927)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 269, 833)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2201)
[M::mem_pestat] mean and std.dev: (349.00, 360.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2885)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 365, 764)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1908)
[M::mem_pestat] mean and std.dev: (484.65, 449.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2480)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698814 reads in 169.303 CPU sec, 5.440 real sec
[M::mem_process_seqs] Processed 697702 reads in 111.537 CPU sec, 3.538 real sec
sorting block 16, #reads = 1089910 mem = 536880183 peak = 877924352
[M::process] read 696610 sequences (100000288 bp) in 2.363 CPU sec, 2.486 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 291302, 27, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 434, 861)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2179)
[M::mem_pestat] mean and std.dev: (546.27, 486.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2838)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 744)
[M::mem_pestat] mean and std.dev: (271.89, 135.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 937)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 471, 808)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2036)
[M::mem_pestat] mean and std.dev: (527.72, 475.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2650)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 297, 944)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2474)
[M::mem_pestat] mean and std.dev: (661.34, 757.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3693)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696282 sequences (100000273 bp) in 2.442 CPU sec, 2.629 real sec...
sorting block 17, #reads = 1089138 mem = 536877818 peak = 885334016
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 290745, 27, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 365, 861)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2153)
[M::mem_pestat] mean and std.dev: (407.34, 278.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2799)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 249, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (274.28, 137.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (292, 459, 1067)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2617)
[M::mem_pestat] mean and std.dev: (713.81, 673.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3407)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 314, 621)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1505)
[M::mem_pestat] mean and std.dev: (415.29, 293.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1947)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696792 reads in 165.927 CPU sec, 5.342 real sec
[M::mem_process_seqs] Processed 696610 reads in 109.205 CPU sec, 3.482 real sec
[M::process] read 696634 sequences (100000080 bp) in 2.224 CPU sec, 2.375 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 290566, 24, 104)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 290, 1068)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2890)
[M::mem_pestat] mean and std.dev: (488.49, 515.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3801)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 250, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (274.54, 137.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 946)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (118, 415, 1652)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4720)
[M::mem_pestat] mean and std.dev: (631.61, 707.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6254)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 322, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 953)
[M::mem_pestat] mean and std.dev: (357.94, 197.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1201)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 18, #reads = 1088476 mem = 536883385 peak = 885334016
[M::process] read 696300 sequences (100000014 bp) in 2.281 CPU sec, 2.590 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 290911, 36, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 269, 646)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1542)
[M::mem_pestat] mean and std.dev: (378.98, 347.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1990)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 744)
[M::mem_pestat] mean and std.dev: (271.94, 135.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 937)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (72, 515, 937)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2667)
[M::mem_pestat] mean and std.dev: (476.03, 449.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3532)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 307, 740)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1822)
[M::mem_pestat] mean and std.dev: (419.96, 345.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2363)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696282 reads in 167.197 CPU sec, 5.414 real sec
[M::mem_process_seqs] Processed 696634 reads in 109.869 CPU sec, 3.512 real sec
[M::process] read 695508 sequences (100000115 bp) in 2.384 CPU sec, 2.520 real sec...
sorting block 19, #reads = 1088185 mem = 536881483 peak = 885334016
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 290036, 29, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 308, 833)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2167)
[M::mem_pestat] mean and std.dev: (488.43, 437.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2834)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 744)
[M::mem_pestat] mean and std.dev: (272.36, 135.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 937)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 562, 983)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2475)
[M::mem_pestat] mean and std.dev: (751.61, 715.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3615)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 375, 972)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2580)
[M::mem_pestat] mean and std.dev: (669.12, 696.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3455)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695624 sequences (100000205 bp) in 2.514 CPU sec, 2.825 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 290105, 28, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 266, 594)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1458)
[M::mem_pestat] mean and std.dev: (307.73, 210.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1890)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 249, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 746)
[M::mem_pestat] mean and std.dev: (274.35, 136.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 939)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (374, 691, 1725)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4427)
[M::mem_pestat] mean and std.dev: (1038.04, 1080.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5778)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 292, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1039)
[M::mem_pestat] mean and std.dev: (295.73, 172.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1329)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696300 reads in 167.853 CPU sec, 5.471 real sec
[M::mem_process_seqs] Processed 695508 reads in 111.007 CPU sec, 3.591 real sec
sorting block 20, #reads = 1088345 mem = 536878775 peak = 885334016
[M::process] read 695066 sequences (100000152 bp) in 2.982 CPU sec, 3.248 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 290212, 35, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 239, 487)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1119)
[M::mem_pestat] mean and std.dev: (307.89, 217.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1435)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 249, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (274.43, 136.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 946)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (249, 795, 1184)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3054)
[M::mem_pestat] mean and std.dev: (772.94, 682.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3989)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 341, 529)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1145)
[M::mem_pestat] mean and std.dev: (356.50, 231.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1453)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695624 reads in 94.519 CPU sec, 3.218 real sec
[M::process] read 693870 sequences (100000081 bp) in 2.483 CPU sec, 2.757 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 289989, 32, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 290, 494)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1162)
[M::mem_pestat] mean and std.dev: (310.37, 221.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1496)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 253, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 762)
[M::mem_pestat] mean and std.dev: (277.80, 138.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 960)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 598, 1140)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3100)
[M::mem_pestat] mean and std.dev: (600.28, 567.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4080)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 280, 528)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1270)
[M::mem_pestat] mean and std.dev: (328.79, 257.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1641)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 21, #reads = 1086920 mem = 536877402 peak = 885334016
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 288995, 19, 84)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 254, 589)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1437)
[M::mem_pestat] mean and std.dev: (316.25, 296.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1861)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 256, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (279.28, 137.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 962)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (381, 747, 4212)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11874)
[M::mem_pestat] mean and std.dev: (2493.26, 3174.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 15705)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 336, 569)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1241)
[M::mem_pestat] mean and std.dev: (335.83, 188.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1577)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700900 sequences (100000072 bp) in 2.617 CPU sec, 2.878 real sec...
[M::mem_process_seqs] Processed 695066 reads in 166.948 CPU sec, 5.457 real sec
[M::mem_process_seqs] Processed 693870 reads in 109.552 CPU sec, 3.577 real sec
sorting block 22, #reads = 1087750 mem = 536879753 peak = 885334016
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 292270, 26, 81)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 289, 423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 935)
[M::mem_pestat] mean and std.dev: (276.00, 154.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1191)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 716)
[M::mem_pestat] mean and std.dev: (261.36, 132.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 902)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 491, 2412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6740)
[M::mem_pestat] mean and std.dev: (918.80, 944.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8904)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 284, 663)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1611)
[M::mem_pestat] mean and std.dev: (450.84, 386.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2085)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700208 sequences (100000063 bp) in 2.435 CPU sec, 2.714 real sec...
[M::mem_process_seqs] Processed 700900 reads in 92.757 CPU sec, 3.241 real sec
[M::process] read 699090 sequences (100000168 bp) in 2.372 CPU sec, 2.705 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 291859, 26, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 266, 567)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1319)
[M::mem_pestat] mean and std.dev: (336.39, 259.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1695)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 238, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 729)
[M::mem_pestat] mean and std.dev: (264.50, 134.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 919)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 371, 988)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2482)
[M::mem_pestat] mean and std.dev: (568.38, 505.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3229)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 338, 606)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1438)
[M::mem_pestat] mean and std.dev: (392.04, 284.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1854)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700208 reads in 94.344 CPU sec, 3.296 real sec
sorting block 23, #reads = 1086728 mem = 536880479 peak = 885334016
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 291392, 11, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 317, 681)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1661)
[M::mem_pestat] mean and std.dev: (377.14, 255.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2151)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 241, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 737)
[M::mem_pestat] mean and std.dev: (267.65, 135.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 929)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (312, 420, 521)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 939)
[M::mem_pestat] mean and std.dev: (377.36, 189.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1148)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 342, 820)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2016)
[M::mem_pestat] mean and std.dev: (477.02, 397.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2614)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698080 sequences (100000008 bp) in 2.611 CPU sec, 2.871 real sec...
[M::mem_process_seqs] Processed 699090 reads in 94.888 CPU sec, 3.360 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 291096, 23, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 290, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 865)
[M::mem_pestat] mean and std.dev: (300.77, 132.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1076)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 742)
[M::mem_pestat] mean and std.dev: (269.95, 136.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 935)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (689, 1004, 2341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5645)
[M::mem_pestat] mean and std.dev: (1320.25, 947.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7297)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 367, 1393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3825)
[M::mem_pestat] mean and std.dev: (748.03, 740.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5041)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697846 sequences (100000202 bp) in 2.763 CPU sec, 3.106 real sec...
sorting block 24, #reads = 1092314 mem = 536882125 peak = 885334016
[M::mem_process_seqs] Processed 698080 reads in 94.068 CPU sec, 3.274 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 291240, 29, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 233, 667)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1693)
[M::mem_pestat] mean and std.dev: (334.89, 264.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2206)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 742)
[M::mem_pestat] mean and std.dev: (270.17, 136.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 935)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 349, 991)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2647)
[M::mem_pestat] mean and std.dev: (346.38, 318.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3475)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 390, 523)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1129)
[M::mem_pestat] mean and std.dev: (345.07, 185.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1432)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697024 sequences (100000108 bp) in 2.587 CPU sec, 3.182 real sec...
[M::mem_process_seqs] Processed 697846 reads in 97.500 CPU sec, 3.459 real sec
sorting block 25, #reads = 1090970 mem = 536879096 peak = 885334016
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 290860, 26, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 274, 575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1323)
[M::mem_pestat] mean and std.dev: (362.96, 262.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1697)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (273.67, 138.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (106, 727, 2169)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6295)
[M::mem_pestat] mean and std.dev: (1251.84, 1408.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8358)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 271, 878)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2276)
[M::mem_pestat] mean and std.dev: (477.58, 480.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2975)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696794 sequences (100000016 bp) in 2.430 CPU sec, 2.689 real sec...
[M::mem_process_seqs] Processed 697024 reads in 91.915 CPU sec, 3.254 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 290500, 21, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (126, 199, 579)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1485)
[M::mem_pestat] mean and std.dev: (285.24, 248.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1938)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 246, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 744)
[M::mem_pestat] mean and std.dev: (271.77, 135.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 937)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (481, 950, 2487)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6499)
[M::mem_pestat] mean and std.dev: (1419.10, 1376.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8505)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 294, 779)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1967)
[M::mem_pestat] mean and std.dev: (499.58, 459.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2561)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696486 sequences (100000102 bp) in 2.937 CPU sec, 3.139 real sec...
[M::mem_process_seqs] Processed 696794 reads in 94.475 CPU sec, 3.239 real sec
sorting block 26, #reads = 1090712 mem = 536879400 peak = 885334016
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 290341, 28, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 225, 390)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 870)
[M::mem_pestat] mean and std.dev: (251.10, 148.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1110)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 744)
[M::mem_pestat] mean and std.dev: (272.56, 136.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 937)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 614, 1166)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3222)
[M::mem_pestat] mean and std.dev: (690.25, 560.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4250)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 334, 552)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1266)
[M::mem_pestat] mean and std.dev: (367.29, 257.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1623)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696240 sequences (100000212 bp) in 2.400 CPU sec, 2.760 real sec...
[M::mem_process_seqs] Processed 696486 reads in 94.383 CPU sec, 3.269 real sec
sorting block 27, #reads = 1089593 mem = 536880640 peak = 885334016
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 290101, 22, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 297, 721)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1795)
[M::mem_pestat] mean and std.dev: (429.08, 360.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2332)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 248, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 745)
[M::mem_pestat] mean and std.dev: (272.76, 135.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 938)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 546, 1538)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4216)
[M::mem_pestat] mean and std.dev: (931.95, 1088.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5555)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 235, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1051)
[M::mem_pestat] mean and std.dev: (303.93, 205.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1343)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695356 sequences (100000224 bp) in 2.390 CPU sec, 2.707 real sec...
[M::mem_process_seqs] Processed 696240 reads in 94.480 CPU sec, 3.308 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 289951, 25, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 290, 748)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1864)
[M::mem_pestat] mean and std.dev: (332.02, 236.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2422)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 250, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 749)
[M::mem_pestat] mean and std.dev: (274.61, 136.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 943)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (468, 806, 2779)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7401)
[M::mem_pestat] mean and std.dev: (1592.60, 1811.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9712)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (270, 361, 738)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1674)
[M::mem_pestat] mean and std.dev: (483.08, 324.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2142)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695328 sequences (100000153 bp) in 2.559 CPU sec, 2.902 real sec...
[M::mem_process_seqs] Processed 695356 reads in 93.147 CPU sec, 3.194 real sec
sorting block 28, #reads = 1087112 mem = 536878279 peak = 885334016
[M::process] read 694398 sequences (100000277 bp) in 2.312 CPU sec, 2.635 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 290149, 26, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 259, 501)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1213)
[M::mem_pestat] mean and std.dev: (323.64, 241.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1569)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 251, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 744)
[M::mem_pestat] mean and std.dev: (274.54, 135.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 936)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (401, 607, 1270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3008)
[M::mem_pestat] mean and std.dev: (856.27, 651.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3877)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 359, 718)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1678)
[M::mem_pestat] mean and std.dev: (432.86, 348.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2158)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695328 reads in 95.115 CPU sec, 3.375 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 289670, 23, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 232, 283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 507)
[M::mem_pestat] mean and std.dev: (222.44, 85.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 619)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 255, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (278.61, 137.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 499, 872)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2328)
[M::mem_pestat] mean and std.dev: (509.00, 499.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3056)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 338, 604)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1386)
[M::mem_pestat] mean and std.dev: (433.20, 309.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1777)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 29, #reads = 1087349 mem = 536877028 peak = 885334016
[M::process] read 702176 sequences (100000271 bp) in 2.684 CPU sec, 2.919 real sec...
[M::mem_process_seqs] Processed 694398 reads in 94.956 CPU sec, 3.286 real sec
[M::process] read 703234 sequences (100000158 bp) in 2.440 CPU sec, 2.821 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 292374, 23, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 207, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1011)
[M::mem_pestat] mean and std.dev: (292.47, 214.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1293)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 230, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 705)
[M::mem_pestat] mean and std.dev: (258.03, 131.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 888)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (333, 873, 2705)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7449)
[M::mem_pestat] mean and std.dev: (1406.39, 1441.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9821)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 292, 573)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1383)
[M::mem_pestat] mean and std.dev: (333.83, 268.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1788)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702176 reads in 101.076 CPU sec, 3.614 real sec
sorting block 30, #reads = 1087990 mem = 536880905 peak = 885334016
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 293334, 29, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 338, 634)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1556)
[M::mem_pestat] mean and std.dev: (421.90, 352.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2017)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (255.94, 131.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 882)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (651, 1035, 2903)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7407)
[M::mem_pestat] mean and std.dev: (1481.86, 1236.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9659)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 370, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 928)
[M::mem_pestat] mean and std.dev: (311.98, 166.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1172)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702024 sequences (100000113 bp) in 2.696 CPU sec, 3.097 real sec...
[M::mem_process_seqs] Processed 703234 reads in 98.026 CPU sec, 3.457 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 292976, 17, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 243, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1044)
[M::mem_pestat] mean and std.dev: (294.37, 212.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1341)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 232, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 717)
[M::mem_pestat] mean and std.dev: (260.33, 133.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 904)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 492, 1523)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4189)
[M::mem_pestat] mean and std.dev: (867.29, 834.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5522)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 288, 522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1104)
[M::mem_pestat] mean and std.dev: (345.00, 224.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1395)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 31, #reads = 1087696 mem = 536879935 peak = 885334016
[M::process] read 700410 sequences (100000215 bp) in 2.691 CPU sec, 3.035 real sec...
[M::mem_process_seqs] Processed 702024 reads in 98.146 CPU sec, 3.466 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 291982, 21, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 399, 1349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3711)
[M::mem_pestat] mean and std.dev: (688.02, 704.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4892)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 236, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 728)
[M::mem_pestat] mean and std.dev: (264.24, 135.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 918)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 521, 963)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2531)
[M::mem_pestat] mean and std.dev: (598.14, 522.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3315)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 239, 417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 855)
[M::mem_pestat] mean and std.dev: (275.35, 121.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1074)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699020 sequences (100000155 bp) in 2.731 CPU sec, 3.216 real sec...
[M::mem_process_seqs] Processed 700410 reads in 100.940 CPU sec, 3.601 real sec
sorting block 32, #reads = 1092295 mem = 536880197 peak = 885334016
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 292030, 20, 89)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 269, 612)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1518)
[M::mem_pestat] mean and std.dev: (357.57, 283.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1971)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 241, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 746)
[M::mem_pestat] mean and std.dev: (269.13, 137.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 941)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (108, 762, 2192)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6360)
[M::mem_pestat] mean and std.dev: (1131.95, 1322.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8444)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 310, 475)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1025)
[M::mem_pestat] mean and std.dev: (298.35, 151.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1300)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698552 sequences (100000009 bp) in 2.540 CPU sec, 2.909 real sec...
[M::mem_process_seqs] Processed 699020 reads in 97.981 CPU sec, 3.469 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 291336, 26, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 306, 751)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1901)
[M::mem_pestat] mean and std.dev: (448.78, 413.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2476)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 242, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 749)
[M::mem_pestat] mean and std.dev: (270.12, 138.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 945)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 778, 1152)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3086)
[M::mem_pestat] mean and std.dev: (713.84, 495.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4053)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 389, 745)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1815)
[M::mem_pestat] mean and std.dev: (510.81, 435.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2350)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 33, #reads = 1089275 mem = 536881209 peak = 885334016
[M::process] read 697812 sequences (100000195 bp) in 2.569 CPU sec, 2.976 real sec...
[M::mem_process_seqs] Processed 698552 reads in 100.011 CPU sec, 3.555 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 291128, 28, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 293, 538)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1268)
[M::mem_pestat] mean and std.dev: (322.95, 214.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1633)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (271.51, 138.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 943)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (288, 1301, 3289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9291)
[M::mem_pestat] mean and std.dev: (2343.68, 2705.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13167)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 280, 434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 890)
[M::mem_pestat] mean and std.dev: (306.80, 174.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1118)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697296 sequences (100000223 bp) in 2.495 CPU sec, 2.845 real sec...
[M::mem_process_seqs] Processed 697812 reads in 99.364 CPU sec, 3.451 real sec
sorting block 34, #reads = 1089505 mem = 536877958 peak = 888573952
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 290784, 19, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 251, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 806)
[M::mem_pestat] mean and std.dev: (241.54, 113.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1023)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 246, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 749)
[M::mem_pestat] mean and std.dev: (272.57, 138.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 944)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (311, 566, 1123)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2747)
[M::mem_pestat] mean and std.dev: (699.22, 609.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3559)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 277, 510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1126)
[M::mem_pestat] mean and std.dev: (316.73, 190.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1434)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696732 sequences (100000047 bp) in 2.693 CPU sec, 3.011 real sec...
[M::mem_process_seqs] Processed 697296 reads in 98.568 CPU sec, 3.395 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 290437, 37, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 272, 641)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1587)
[M::mem_pestat] mean and std.dev: (368.50, 299.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2060)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
sorting block 35, #reads = 1086603 mem = 536877526 peak = 888573952
[M::mem_pestat] (25, 50, 75) percentile: (165, 246, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (273.19, 137.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 945)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 486, 851)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2117)
[M::mem_pestat] mean and std.dev: (509.06, 384.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2750)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 294, 654)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1622)
[M::mem_pestat] mean and std.dev: (355.28, 266.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2106)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696584 sequences (100000252 bp) in 2.544 CPU sec, 2.848 real sec...
[M::mem_process_seqs] Processed 696732 reads in 101.559 CPU sec, 3.482 real sec
[M::process] read 696430 sequences (100000107 bp) in 2.546 CPU sec, 2.848 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 290369, 13, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 263, 594)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1466)
[M::mem_pestat] mean and std.dev: (326.02, 271.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1902)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 744)
[M::mem_pestat] mean and std.dev: (272.21, 135.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 937)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (738, 968, 2259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5301)
[M::mem_pestat] mean and std.dev: (1259.50, 1180.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6822)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 301, 495)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1063)
[M::mem_pestat] mean and std.dev: (325.29, 184.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1347)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696584 reads in 101.073 CPU sec, 3.454 real sec
sorting block 36, #reads = 1087004 mem = 536879256 peak = 888573952
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 290667, 16, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 269, 511)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1245)
[M::mem_pestat] mean and std.dev: (298.75, 225.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1612)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 744)
[M::mem_pestat] mean and std.dev: (272.35, 136.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 937)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 458, 1013)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2689)
[M::mem_pestat] mean and std.dev: (391.31, 335.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3527)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 290, 511)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1141)
[M::mem_pestat] mean and std.dev: (308.85, 198.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1456)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697342 sequences (100000122 bp) in 2.644 CPU sec, 2.936 real sec...
[M::mem_process_seqs] Processed 696430 reads in 100.497 CPU sec, 3.443 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 290994, 31, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 224, 520)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1274)
[M::mem_pestat] mean and std.dev: (300.49, 243.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1651)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 244, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 737)
[M::mem_pestat] mean and std.dev: (269.91, 135.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 928)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 429, 1193)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3231)
[M::mem_pestat] mean and std.dev: (738.50, 768.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4250)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 377, 641)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1529)
[M::mem_pestat] mean and std.dev: (400.48, 262.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1973)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706182 sequences (100000124 bp) in 2.805 CPU sec, 3.130 real sec...
sorting block 37, #reads = 1085672 mem = 536881235 peak = 914714624
[M::mem_process_seqs] Processed 697342 reads in 102.049 CPU sec, 3.509 real sec
[M::process] read 703380 sequences (100000169 bp) in 2.294 CPU sec, 2.676 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 294058, 27, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 286, 621)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1549)
[M::mem_pestat] mean and std.dev: (383.58, 356.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2013)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 219, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 660)
[M::mem_pestat] mean and std.dev: (245.02, 123.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 830)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (364, 1091, 1523)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3841)
[M::mem_pestat] mean and std.dev: (894.76, 665.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5000)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 372, 835)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2021)
[M::mem_pestat] mean and std.dev: (479.23, 383.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2614)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706182 reads in 105.692 CPU sec, 3.685 real sec
sorting block 38, #reads = 1084602 mem = 536879201 peak = 914714624
[M::process] read 703212 sequences (100000020 bp) in 2.751 CPU sec, 3.131 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 293523, 15, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 267, 771)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1975)
[M::mem_pestat] mean and std.dev: (433.55, 401.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2577)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 694)
[M::mem_pestat] mean and std.dev: (254.30, 128.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 874)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 730, 1190)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3098)
[M::mem_pestat] mean and std.dev: (763.67, 643.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4052)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 293, 412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 830)
[M::mem_pestat] mean and std.dev: (284.88, 139.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1039)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703380 reads in 103.373 CPU sec, 3.611 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 293308, 24, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 317, 600)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1330)
[M::mem_pestat] mean and std.dev: (335.91, 186.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1695)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (254.33, 129.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (402, 1105, 1531)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3789)
[M::mem_pestat] mean and std.dev: (993.73, 807.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4918)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 345, 766)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1920)
[M::mem_pestat] mean and std.dev: (469.15, 375.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2497)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701360 sequences (100000049 bp) in 2.956 CPU sec, 3.312 real sec...
[M::mem_process_seqs] Processed 703212 reads in 105.195 CPU sec, 3.666 real sec
sorting block 39, #reads = 1088406 mem = 536882922 peak = 914714624
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 293199, 17, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 239, 537)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1317)
[M::mem_pestat] mean and std.dev: (307.98, 251.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1707)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 233, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 715)
[M::mem_pestat] mean and std.dev: (260.53, 132.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 901)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (368, 809, 1202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2870)
[M::mem_pestat] mean and std.dev: (848.29, 473.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3704)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 294, 384)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (281.83, 119.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 831)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700262 sequences (100000227 bp) in 2.726 CPU sec, 2.986 real sec...
[M::mem_process_seqs] Processed 701360 reads in 104.068 CPU sec, 3.656 real sec
sorting block 40, #reads = 1089101 mem = 536878672 peak = 914714624
[M::process] read 699388 sequences (100000129 bp) in 2.446 CPU sec, 2.913 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 292614, 24, 97)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 329, 1875)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5191)
[M::mem_pestat] mean and std.dev: (705.82, 972.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6849)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 236, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 728)
[M::mem_pestat] mean and std.dev: (263.73, 134.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 918)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 480, 1915)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5317)
[M::mem_pestat] mean and std.dev: (819.83, 916.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7018)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 302, 596)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1320)
[M::mem_pestat] mean and std.dev: (400.22, 283.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1682)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700262 reads in 102.613 CPU sec, 3.707 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 292414, 26, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 242, 548)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1302)
[M::mem_pestat] mean and std.dev: (293.39, 192.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1679)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 240, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 742)
[M::mem_pestat] mean and std.dev: (267.87, 137.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 936)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (393, 555, 916)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1962)
[M::mem_pestat] mean and std.dev: (627.08, 418.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2485)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 296, 603)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1447)
[M::mem_pestat] mean and std.dev: (403.18, 301.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1869)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698286 sequences (100000193 bp) in 2.738 CPU sec, 3.216 real sec...
[M::mem_process_seqs] Processed 699388 reads in 103.274 CPU sec, 3.628 real sec
sorting block 41, #reads = 1088171 mem = 536884746 peak = 914714624
[M::process] read 697478 sequences (100000172 bp) in 2.564 CPU sec, 2.959 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 291615, 32, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 297, 637)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1605)
[M::mem_pestat] mean and std.dev: (355.33, 318.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2089)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 242, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 744)
[M::mem_pestat] mean and std.dev: (269.95, 137.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 938)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (257, 1233, 1921)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5249)
[M::mem_pestat] mean and std.dev: (1462.47, 1374.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6960)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 278, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 966)
[M::mem_pestat] mean and std.dev: (323.48, 201.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1222)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698286 reads in 104.983 CPU sec, 3.695 real sec
sorting block 42, #reads = 1086695 mem = 536882977 peak = 914714624
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 290759, 28, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 354, 562)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1352)
[M::mem_pestat] mean and std.dev: (359.71, 269.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1747)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 745)
[M::mem_pestat] mean and std.dev: (271.03, 137.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 939)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (441, 695, 1123)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2487)
[M::mem_pestat] mean and std.dev: (764.08, 453.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3169)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 229, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 991)
[M::mem_pestat] mean and std.dev: (293.20, 195.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1259)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696934 sequences (100000220 bp) in 2.570 CPU sec, 2.997 real sec...
[M::mem_process_seqs] Processed 697478 reads in 101.578 CPU sec, 3.593 real sec
[M::process] read 696488 sequences (100000215 bp) in 2.349 CPU sec, 2.788 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 290339, 31, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 293, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 954)
[M::mem_pestat] mean and std.dev: (315.61, 181.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1206)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 246, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 749)
[M::mem_pestat] mean and std.dev: (273.03, 138.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 944)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (318, 568, 878)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1998)
[M::mem_pestat] mean and std.dev: (623.29, 437.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2558)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 307, 509)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1183)
[M::mem_pestat] mean and std.dev: (311.86, 168.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1520)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696934 reads in 102.273 CPU sec, 3.621 real sec
sorting block 43, #reads = 1086467 mem = 536877918 peak = 915959808
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 290614, 18, 97)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 351, 736)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1868)
[M::mem_pestat] mean and std.dev: (487.50, 444.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2434)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 759)
[M::mem_pestat] mean and std.dev: (275.12, 140.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 957)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (60, 771, 866)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2478)
[M::mem_pestat] mean and std.dev: (539.12, 538.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3284)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 335, 735)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1807)
[M::mem_pestat] mean and std.dev: (445.66, 359.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2343)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697522 sequences (100000060 bp) in 2.846 CPU sec, 3.188 real sec...
[M::mem_process_seqs] Processed 696488 reads in 99.517 CPU sec, 3.630 real sec
[M::process] read 704418 sequences (100000020 bp) in 2.751 CPU sec, 3.020 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 290849, 28, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 309, 760)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1896)
[M::mem_pestat] mean and std.dev: (387.64, 336.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2464)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 243, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (272.45, 140.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 951)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (109, 809, 1209)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3409)
[M::mem_pestat] mean and std.dev: (858.54, 921.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4544)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 347, 734)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1780)
[M::mem_pestat] mean and std.dev: (449.04, 403.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2303)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 44, #reads = 1086195 mem = 536881106 peak = 915959808
[M::mem_process_seqs] Processed 697522 reads in 110.758 CPU sec, 3.884 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 293501, 21, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 281, 516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1242)
[M::mem_pestat] mean and std.dev: (341.00, 268.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1605)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 225, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (252.13, 128.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 865)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 584, 1694)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4626)
[M::mem_pestat] mean and std.dev: (1039.57, 1065.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6092)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 407, 647)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1553)
[M::mem_pestat] mean and std.dev: (439.78, 323.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2006)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701736 sequences (100000269 bp) in 2.432 CPU sec, 2.959 real sec...
[M::mem_process_seqs] Processed 704418 reads in 97.396 CPU sec, 3.521 real sec
sorting block 45, #reads = 1085322 mem = 536879034 peak = 915959808
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 293185, 23, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 309, 659)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1659)
[M::mem_pestat] mean and std.dev: (439.87, 363.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2159)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 232, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 708)
[M::mem_pestat] mean and std.dev: (259.10, 131.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 892)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 360, 1062)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2738)
[M::mem_pestat] mean and std.dev: (465.71, 410.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3576)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 303, 533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1259)
[M::mem_pestat] mean and std.dev: (327.43, 234.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1622)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700772 sequences (100000095 bp) in 2.448 CPU sec, 2.815 real sec...
[M::mem_process_seqs] Processed 701736 reads in 97.832 CPU sec, 3.480 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 292752, 29, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (283, 467, 812)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1870)
[M::mem_pestat] mean and std.dev: (537.62, 408.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2399)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 234, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 718)
[M::mem_pestat] mean and std.dev: (261.36, 132.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 905)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (262, 412, 1136)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2884)
[M::mem_pestat] mean and std.dev: (643.07, 600.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3758)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 354, 675)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1565)
[M::mem_pestat] mean and std.dev: (380.96, 243.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2010)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700132 sequences (100000144 bp) in 2.634 CPU sec, 2.926 real sec...
sorting block 46, #reads = 1085270 mem = 536881816 peak = 915959808
[M::mem_process_seqs] Processed 700772 reads in 97.082 CPU sec, 3.486 real sec
[M::process] read 699940 sequences (100000040 bp) in 2.530 CPU sec, 2.957 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (87, 292540, 23, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 307, 612)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1478)
[M::mem_pestat] mean and std.dev: (338.95, 238.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1911)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 237, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 729)
[M::mem_pestat] mean and std.dev: (264.76, 134.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 919)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (382, 636, 1160)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2716)
[M::mem_pestat] mean and std.dev: (647.60, 461.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3494)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 415, 875)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2141)
[M::mem_pestat] mean and std.dev: (623.34, 579.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2943)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700132 reads in 103.523 CPU sec, 3.706 real sec
sorting block 47, #reads = 1091067 mem = 536881457 peak = 917667840
[M::process] read 699140 sequences (100000172 bp) in 2.337 CPU sec, 2.573 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 291989, 19, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 249, 605)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1455)
[M::mem_pestat] mean and std.dev: (360.62, 265.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1880)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 238, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 735)
[M::mem_pestat] mean and std.dev: (265.67, 135.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 927)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (481, 951, 1655)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4003)
[M::mem_pestat] mean and std.dev: (938.65, 797.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5177)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 300, 631)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1537)
[M::mem_pestat] mean and std.dev: (314.41, 208.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1990)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699940 reads in 100.445 CPU sec, 3.578 real sec
[M::process] read 698068 sequences (100000021 bp) in 2.257 CPU sec, 2.541 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 292479, 25, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 261, 769)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1941)
[M::mem_pestat] mean and std.dev: (436.19, 432.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2527)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 240, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 742)
[M::mem_pestat] mean and std.dev: (268.04, 136.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 936)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (493, 881, 2102)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5320)
[M::mem_pestat] mean and std.dev: (1125.91, 977.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6929)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 384, 570)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1284)
[M::mem_pestat] mean and std.dev: (396.52, 220.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1641)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 48, #reads = 1089264 mem = 536877090 peak = 973697024
[M::mem_process_seqs] Processed 699140 reads in 97.364 CPU sec, 3.333 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 291448, 31, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 308, 571)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1323)
[M::mem_pestat] mean and std.dev: (336.44, 200.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1699)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 244, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (270.98, 137.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 946)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (353, 906, 2374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6416)
[M::mem_pestat] mean and std.dev: (1121.66, 1074.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8437)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 304, 744)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1854)
[M::mem_pestat] mean and std.dev: (459.73, 408.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2409)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697582 sequences (100000048 bp) in 2.621 CPU sec, 2.944 real sec...
[M::mem_process_seqs] Processed 698068 reads in 100.779 CPU sec, 3.483 real sec
sorting block 49, #reads = 1088552 mem = 536878507 peak = 973697024
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 291156, 18, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 301, 535)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1235)
[M::mem_pestat] mean and std.dev: (364.67, 263.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1585)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (271.53, 137.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 943)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (119, 629, 1757)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5033)
[M::mem_pestat] mean and std.dev: (806.06, 914.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6671)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 394, 1305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3479)
[M::mem_pestat] mean and std.dev: (659.68, 561.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4566)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697462 sequences (100000290 bp) in 2.521 CPU sec, 2.856 real sec...
[M::mem_process_seqs] Processed 697582 reads in 100.652 CPU sec, 3.512 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 291199, 38, 89)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 264, 609)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1417)
[M::mem_pestat] mean and std.dev: (382.05, 312.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1821)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 243, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 739)
[M::mem_pestat] mean and std.dev: (270.32, 136.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 931)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 633, 1704)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4734)
[M::mem_pestat] mean and std.dev: (722.88, 660.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6249)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 287, 580)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1358)
[M::mem_pestat] mean and std.dev: (379.38, 295.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1747)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697118 sequences (100000224 bp) in 2.684 CPU sec, 2.926 real sec...
sorting block 50, #reads = 1087779 mem = 536880527 peak = 973697024
[M::mem_process_seqs] Processed 697462 reads in 102.073 CPU sec, 3.538 real sec
[M::process] read 697166 sequences (100000089 bp) in 2.548 CPU sec, 2.935 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 290897, 25, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 283, 522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1236)
[M::mem_pestat] mean and std.dev: (363.92, 296.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1593)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 245, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 743)
[M::mem_pestat] mean and std.dev: (271.22, 136.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 936)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (268, 646, 1972)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5380)
[M::mem_pestat] mean and std.dev: (1069.25, 1040.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7084)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 262, 420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 916)
[M::mem_pestat] mean and std.dev: (253.91, 117.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1164)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697118 reads in 109.551 CPU sec, 3.760 real sec
sorting block 51, #reads = 1086895 mem = 536883148 peak = 973697024
[M::process] read 705292 sequences (100000149 bp) in 2.774 CPU sec, 3.085 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 291095, 22, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 361, 562)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1310)
[M::mem_pestat] mean and std.dev: (368.65, 254.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1684)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 244, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 746)
[M::mem_pestat] mean and std.dev: (271.75, 138.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 940)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (286, 451, 2007)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5449)
[M::mem_pestat] mean and std.dev: (1130.95, 1396.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7170)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 344, 655)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1589)
[M::mem_pestat] mean and std.dev: (413.48, 324.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2056)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697166 reads in 103.867 CPU sec, 3.537 real sec
[M::process] read 705172 sequences (100000139 bp) in 2.289 CPU sec, 2.565 real sec...
sorting block 52, #reads = 1083839 mem = 536881050 peak = 973697024
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 293880, 23, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (128, 307, 913)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2483)
[M::mem_pestat] mean and std.dev: (586.61, 574.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3268)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 222, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 670)
[M::mem_pestat] mean and std.dev: (248.18, 125.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 843)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (91, 428, 1492)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4294)
[M::mem_pestat] mean and std.dev: (592.60, 653.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5695)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 338, 631)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1449)
[M::mem_pestat] mean and std.dev: (375.51, 240.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1858)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704812 sequences (100000023 bp) in 2.470 CPU sec, 2.763 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 293913, 40, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 288, 701)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1713)
[M::mem_pestat] mean and std.dev: (374.90, 288.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2219)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 222, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 676)
[M::mem_pestat] mean and std.dev: (248.85, 126.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 851)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 587, 1056)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2864)
[M::mem_pestat] mean and std.dev: (660.58, 654.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3768)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 228, 404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 854)
[M::mem_pestat] mean and std.dev: (294.55, 172.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1079)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705292 reads in 196.573 CPU sec, 6.491 real sec
[M::mem_process_seqs] Processed 705172 reads in 122.326 CPU sec, 4.014 real sec
sorting block 53, #reads = 1082238 mem = 536879066 peak = 973697024
[M::process] read 704214 sequences (100000098 bp) in 2.542 CPU sec, 2.770 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 294296, 19, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 325, 487)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1153)
[M::mem_pestat] mean and std.dev: (317.73, 209.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1486)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 222, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (248.89, 125.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 844)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (82, 550, 1587)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4597)
[M::mem_pestat] mean and std.dev: (927.26, 956.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6102)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 336, 727)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1765)
[M::mem_pestat] mean and std.dev: (406.79, 310.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2284)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701816 sequences (100000127 bp) in 2.289 CPU sec, 2.507 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 293770, 28, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 332, 865)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2251)
[M::mem_pestat] mean and std.dev: (435.15, 437.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2944)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (250.98, 127.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 856)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (116, 242, 824)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2240)
[M::mem_pestat] mean and std.dev: (345.12, 312.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2948)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 302, 496)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1104)
[M::mem_pestat] mean and std.dev: (339.25, 211.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1408)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704812 reads in 186.249 CPU sec, 6.094 real sec
sorting block 54, #reads = 1090341 mem = 536881648 peak = 973697024
[M::mem_process_seqs] Processed 704214 reads in 120.349 CPU sec, 3.907 real sec
[M::process] read 700424 sequences (100000010 bp) in 2.448 CPU sec, 2.610 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 292757, 18, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 304, 904)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2418)
[M::mem_pestat] mean and std.dev: (548.00, 566.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3175)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 230, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 702)
[M::mem_pestat] mean and std.dev: (258.38, 131.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 884)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (266, 513, 928)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2252)
[M::mem_pestat] mean and std.dev: (487.69, 331.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2914)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 278, 562)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1304)
[M::mem_pestat] mean and std.dev: (325.81, 244.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1675)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 55, #reads = 1087616 mem = 536878479 peak = 973697024
[M::process] read 698724 sequences (100000173 bp) in 2.773 CPU sec, 2.932 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 292643, 23, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 285, 512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1178)
[M::mem_pestat] mean and std.dev: (348.46, 263.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1511)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 731)
[M::mem_pestat] mean and std.dev: (264.51, 136.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 922)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (108, 419, 1062)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2970)
[M::mem_pestat] mean and std.dev: (640.95, 644.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3924)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 342, 746)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1784)
[M::mem_pestat] mean and std.dev: (452.15, 368.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2303)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701816 reads in 185.953 CPU sec, 6.002 real sec
[M::mem_process_seqs] Processed 700424 reads in 120.286 CPU sec, 3.843 real sec
[M::process] read 698252 sequences (100000012 bp) in 2.159 CPU sec, 2.283 real sec...
sorting block 56, #reads = 1087168 mem = 536877696 peak = 973697024
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 291538, 27, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 238, 979)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2587)
[M::mem_pestat] mean and std.dev: (424.75, 447.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3391)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 240, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 734)
[M::mem_pestat] mean and std.dev: (267.78, 136.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 925)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 318, 837)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2233)
[M::mem_pestat] mean and std.dev: (512.00, 512.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2931)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 327, 484)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1068)
[M::mem_pestat] mean and std.dev: (344.14, 193.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1360)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696554 sequences (100000207 bp) in 2.961 CPU sec, 3.163 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 291610, 28, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 234, 404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 882)
[M::mem_pestat] mean and std.dev: (265.75, 148.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1121)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 242, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 738)
[M::mem_pestat] mean and std.dev: (269.10, 136.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 930)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (340, 882, 1258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3094)
[M::mem_pestat] mean and std.dev: (731.44, 561.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4012)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 352, 571)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1207)
[M::mem_pestat] mean and std.dev: (367.27, 213.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1525)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698724 reads in 182.556 CPU sec, 5.859 real sec
[M::mem_process_seqs] Processed 698252 reads in 118.364 CPU sec, 3.768 real sec
[M::process] read 695862 sequences (100000284 bp) in 2.269 CPU sec, 2.337 real sec...
sorting block 57, #reads = 1086255 mem = 536881523 peak = 974888960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 290443, 25, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 323, 638)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1546)
[M::mem_pestat] mean and std.dev: (384.31, 293.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2000)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 245, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 746)
[M::mem_pestat] mean and std.dev: (272.19, 137.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 940)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (108, 687, 793)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2163)
[M::mem_pestat] mean and std.dev: (470.70, 377.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2848)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 283, 1345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3641)
[M::mem_pestat] mean and std.dev: (483.37, 548.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4789)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696110 sequences (100000263 bp) in 2.725 CPU sec, 2.898 real sec...
[M::process] read 53038 sequences (7597920 bp) in 0.425 CPU sec, 0.434 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 290561, 41, 93)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 385, 528)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1182)
[M::mem_pestat] mean and std.dev: (393.16, 260.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1509)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 248, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (274.25, 137.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 946)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (307, 452, 1032)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2482)
[M::mem_pestat] mean and std.dev: (609.97, 445.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3207)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 328, 792)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1938)
[M::mem_pestat] mean and std.dev: (416.43, 329.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2511)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696554 reads in 172.222 CPU sec, 5.550 real sec
sorting block 58, #reads = 1086204 mem = 536879941 peak = 1008840704
[M::mem_process_seqs] Processed 695862 reads in 111.056 CPU sec, 3.555 real sec
sorting block 59, #reads = 1085692 mem = 536876875 peak = 1096060928
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 290559, 19, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 353, 1219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3203)
[M::mem_pestat] mean and std.dev: (594.19, 582.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4195)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 248, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (275.71, 139.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 958)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (307, 463, 1466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3784)
[M::mem_pestat] mean and std.dev: (654.65, 569.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4943)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 293, 753)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1829)
[M::mem_pestat] mean and std.dev: (418.40, 349.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2367)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (7, 22062, 3, 8)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 240, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 729)
[M::mem_pestat] mean and std.dev: (266.10, 133.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 918)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_process_seqs] Processed 696110 reads in 102.219 CPU sec, 3.355 real sec
[M::mem_process_seqs] Processed 53038 reads in 26.980 CPU sec, 0.876 real sec
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 65691448
overall: 69837942784 mem 10754.038 user 380.789 sys 395.479 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1136_27F-T1-TDNA-1_A23MHWWLT4_1.L002\tPU:L002\tSM:1136_27F-T1-TDNA-1_A23MHWWLT4_1\tLB:1136_27F-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 0002.1136_27F-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 0002.1136_27F-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 395.513 sec; CPU: 11134.829 sec
sorting block 60, #reads = 963978 mem = 477044862 peak = 1096060928
uniq header count 1
merging 61 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31 max 192
algo: util-sort
license: sentieon:util=1
output file size: 3661706127
output reads: 66247101
bam_mem_sort: 61 calls 41.809 user 0.390 sys 43.150 real
bam_write: 61 calls 41.166 user 2.829 sys 78.884 real
execute: 1 calls 19.241 user 1.496 sys 419.555 real
merge_files: 1 calls 19.211 user 1.476 sys 23.206 real
parse_chunk: 975 calls 45.740 user 11.760 sys 70.599 real
read_chunk: 2634 calls 24.014 user 17.042 sys 325.454 real
sort_block: 1 calls 16.865 user 16.218 sys 314.846 real
write_chunk: 1657 calls 18.769 user 1.154 sys 22.217 real
overall: 2750554112 mem 900.351 user 46.108 sys 419.575 real
ls: cannot access '*.cram': No such file or directory