This software is licensed to bgold@natera.com by Sentieon Inc. cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1029_BCAN-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam - This software is licensed to bgold@natera.com by Sentieon Inc. version: sentieon-genomics-202308.03 [M::bwa_idx_load_from_disk] read 3171 ALT contigs [M::main_mem] bwa index loaded in 1834.373 CPU sec, 69.092 real sec [M::process] read 869162 sequences (100000132 bp) in 1.226 CPU sec, 1.229 real sec... [M::process] read 867726 sequences (100000067 bp) in 1.679 CPU sec, 1.681 real sec... [M::process] read 866910 sequences (100000192 bp) in 1.795 CPU sec, 1.800 real sec... [M::process] read 867624 sequences (100000032 bp) in 1.601 CPU sec, 1.609 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (89, 292501, 42, 73) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (174, 469, 1115) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2997) [M::mem_pestat] mean and std.dev: (646.06, 619.54) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3938) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (90, 116, 151) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 273) [M::mem_pestat] mean and std.dev: (123.29, 44.70) [M::mem_pestat] low and high boundaries for proper pairs: (1, 334) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (212, 814, 1949) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5423) [M::mem_pestat] mean and std.dev: (994.03, 998.11) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7160) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (191, 725, 1888) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5282) [M::mem_pestat] mean and std.dev: (1034.76, 951.73) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6979) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 293173, 54, 82) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (181, 504, 1368) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3742) [M::mem_pestat] mean and std.dev: (888.30, 908.34) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4929) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (90, 116, 152) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 276) [M::mem_pestat] mean and std.dev: (123.71, 45.14) [M::mem_pestat] low and high boundaries for proper pairs: (1, 338) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (168, 524, 935) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2469) [M::mem_pestat] mean and std.dev: (535.43, 489.17) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3236) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (241, 517, 1141) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2941) [M::mem_pestat] mean and std.dev: (666.35, 615.48) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3841) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 292708, 72, 85) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (251, 539, 1424) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3770) [M::mem_pestat] mean and std.dev: (879.36, 896.85) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4943) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (90, 116, 152) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 276) [M::mem_pestat] mean and std.dev: (123.88, 45.18) [M::mem_pestat] low and high boundaries for proper pairs: (1, 338) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (400, 727, 1305) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3115) [M::mem_pestat] mean and std.dev: (751.76, 553.68) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4020) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (193, 354, 1215) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3259) [M::mem_pestat] mean and std.dev: (574.35, 571.20) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4281) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 869162 reads in 577.204 CPU sec, 18.638 real sec [M::mem_process_seqs] Processed 867726 reads in 466.936 CPU sec, 15.244 real sec sorting block 0, #reads = 1047737 mem = 536883209 peak = 581529600 [M::process] read 865924 sequences (100000044 bp) in 2.433 CPU sec, 2.522 real sec... [M::mem_process_seqs] Processed 866910 reads in 536.344 CPU sec, 17.495 real sec sorting block 1, #reads = 1051464 mem = 536893577 peak = 807391232 [M::process] read 864262 sequences (100000101 bp) in 2.533 CPU sec, 2.632 real sec... [M::process] read 864012 sequences (100000184 bp) in 1.978 CPU sec, 1.988 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 292396, 57, 77) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (221, 711, 1631) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4451) [M::mem_pestat] mean and std.dev: (850.38, 772.16) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5861) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (90, 116, 152) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 276) [M::mem_pestat] mean and std.dev: (124.07, 45.22) [M::mem_pestat] low and high boundaries for proper pairs: (1, 338) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (219, 363, 1149) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3009) [M::mem_pestat] mean and std.dev: (528.50, 528.45) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3939) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (193, 423, 1706) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4732) [M::mem_pestat] mean and std.dev: (848.89, 934.46) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6245) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (81, 293317, 46, 82) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (181, 442, 1113) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2977) [M::mem_pestat] mean and std.dev: (618.37, 605.93) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3909) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (90, 116, 152) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 276) [M::mem_pestat] mean and std.dev: (123.66, 45.12) [M::mem_pestat] low and high boundaries for proper pairs: (1, 338) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (190, 628, 1327) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3601) [M::mem_pestat] mean and std.dev: (835.70, 862.42) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4738) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (219, 393, 961) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2445) [M::mem_pestat] mean and std.dev: (566.45, 541.49) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3187) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 865924 reads in 415.672 CPU sec, 13.371 real sec sorting block 2, #reads = 1051950 mem = 536880917 peak = 819384320 [M::mem_process_seqs] Processed 867624 reads in 478.536 CPU sec, 15.435 real sec sorting block 3, #reads = 1051898 mem = 536883974 peak = 819384320 [M::process] read 861622 sequences (100000145 bp) in 2.915 CPU sec, 3.048 real sec... [M::process] read 861182 sequences (100000210 bp) in 2.064 CPU sec, 2.073 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (87, 290654, 72, 88) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (212, 393, 1058) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2750) [M::mem_pestat] mean and std.dev: (589.16, 545.39) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3596) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (91, 117, 153) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 277) [M::mem_pestat] mean and std.dev: (124.58, 45.58) [M::mem_pestat] low and high boundaries for proper pairs: (1, 339) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (247, 692, 1584) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4258) [M::mem_pestat] mean and std.dev: (995.84, 988.98) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5595) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (209, 446, 1206) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3200) [M::mem_pestat] mean and std.dev: (730.24, 750.10) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4197) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 291812, 54, 87) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (204, 500, 1740) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4812) [M::mem_pestat] mean and std.dev: (930.65, 960.73) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6348) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (91, 116, 153) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 277) [M::mem_pestat] mean and std.dev: (124.49, 45.56) [M::mem_pestat] low and high boundaries for proper pairs: (1, 339) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (218, 511, 1759) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4841) [M::mem_pestat] mean and std.dev: (947.21, 1037.33) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6382) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (225, 405, 1193) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3129) [M::mem_pestat] mean and std.dev: (699.29, 702.65) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4097) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 864012 reads in 428.561 CPU sec, 13.761 real sec sorting block 4, #reads = 1045061 mem = 536892251 peak = 819384320 [M::mem_process_seqs] Processed 864262 reads in 498.324 CPU sec, 16.052 real sec [M::process] read 865628 sequences (100000252 bp) in 3.327 CPU sec, 3.455 real sec... [M::process] read 867214 sequences (100000189 bp) in 2.104 CPU sec, 2.108 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 291244, 68, 93) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (266, 532, 1171) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2981) [M::mem_pestat] mean and std.dev: (748.22, 695.02) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3886) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (91, 117, 154) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 280) [M::mem_pestat] mean and std.dev: (125.34, 46.15) [M::mem_pestat] low and high boundaries for proper pairs: (1, 343) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (158, 317, 1130) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3074) [M::mem_pestat] mean and std.dev: (553.78, 651.78) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4046) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (316, 584, 1106) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2686) [M::mem_pestat] mean and std.dev: (688.73, 615.91) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3476) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 290626, 63, 70) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (197, 490, 1523) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4175) [M::mem_pestat] mean and std.dev: (878.55, 857.72) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5501) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (91, 117, 154) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 280) [M::mem_pestat] mean and std.dev: (125.19, 46.08) [M::mem_pestat] low and high boundaries for proper pairs: (1, 343) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (183, 516, 1453) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3993) [M::mem_pestat] mean and std.dev: (763.97, 775.10) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5263) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (193, 541, 1303) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3523) [M::mem_pestat] mean and std.dev: (713.70, 706.50) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4633) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 861182 reads in 431.702 CPU sec, 13.853 real sec sorting block 5, #reads = 1049152 mem = 536880397 peak = 819384320 [M::mem_process_seqs] Processed 861622 reads in 500.239 CPU sec, 16.095 real sec sorting block 6, #reads = 1049080 mem = 536894360 peak = 912162816 [M::process] read 865984 sequences (100000153 bp) in 3.407 CPU sec, 3.530 real sec... [M::process] read 866572 sequences (100000194 bp) in 2.111 CPU sec, 2.120 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 292457, 57, 83) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (198, 373, 1043) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2733) [M::mem_pestat] mean and std.dev: (620.77, 554.76) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3578) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (90, 116, 152) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 276) [M::mem_pestat] mean and std.dev: (123.82, 45.09) [M::mem_pestat] low and high boundaries for proper pairs: (1, 338) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (213, 566, 1412) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3810) [M::mem_pestat] mean and std.dev: (734.47, 714.29) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5009) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (345, 856, 1599) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4107) [M::mem_pestat] mean and std.dev: (995.51, 783.15) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5361) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (96, 291275, 60, 79) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (174, 322, 1212) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3288) [M::mem_pestat] mean and std.dev: (660.72, 758.63) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4326) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (90, 116, 152) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 276) [M::mem_pestat] mean and std.dev: (124.16, 45.37) [M::mem_pestat] low and high boundaries for proper pairs: (1, 338) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (188, 413, 1028) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2708) [M::mem_pestat] mean and std.dev: (535.45, 493.46) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3548) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (166, 466, 1282) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3514) [M::mem_pestat] mean and std.dev: (736.36, 746.83) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4630) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 867214 reads in 422.931 CPU sec, 13.563 real sec sorting block 7, #reads = 1049736 mem = 536882658 peak = 912162816 [M::mem_process_seqs] Processed 865628 reads in 493.097 CPU sec, 15.863 real sec sorting block 8, #reads = 1050364 mem = 536883729 peak = 912162816 [M::process] read 865438 sequences (100000049 bp) in 3.387 CPU sec, 3.520 real sec... [M::process] read 863846 sequences (100000239 bp) in 2.284 CPU sec, 2.286 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (92, 293409, 42, 71) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (298, 477, 1220) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3064) [M::mem_pestat] mean and std.dev: (674.14, 529.24) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3986) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (90, 116, 152) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 276) [M::mem_pestat] mean and std.dev: (123.89, 45.14) [M::mem_pestat] low and high boundaries for proper pairs: (1, 338) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (195, 483, 1049) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2757) [M::mem_pestat] mean and std.dev: (717.21, 781.08) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3842) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (176, 286, 814) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2090) [M::mem_pestat] mean and std.dev: (401.47, 337.51) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2728) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 292949, 70, 75) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (136, 246, 640) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1648) [M::mem_pestat] mean and std.dev: (370.10, 365.94) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2152) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (90, 116, 153) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 279) [M::mem_pestat] mean and std.dev: (124.29, 45.62) [M::mem_pestat] low and high boundaries for proper pairs: (1, 342) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (232, 613, 2327) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6517) [M::mem_pestat] mean and std.dev: (1330.30, 1498.79) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8612) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (271, 442, 946) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2296) [M::mem_pestat] mean and std.dev: (537.26, 385.19) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2971) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 866572 reads in 417.483 CPU sec, 13.376 real sec sorting block 9, #reads = 1050332 mem = 536889957 peak = 912162816 [M::mem_process_seqs] Processed 865984 reads in 478.031 CPU sec, 15.364 real sec [M::process] read 865236 sequences (100000265 bp) in 3.103 CPU sec, 3.250 real sec... sorting block 10, #reads = 1053790 mem = 536882714 peak = 912162816 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (88, 292083, 63, 74) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (177, 510, 1192) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3222) [M::mem_pestat] mean and std.dev: (596.37, 529.41) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4237) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (90, 116, 152) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 276) [M::mem_pestat] mean and std.dev: (124.14, 45.31) [M::mem_pestat] low and high boundaries for proper pairs: (1, 338) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (277, 650, 1849) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4993) [M::mem_pestat] mean and std.dev: (1037.93, 1022.09) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6565) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (303, 582, 1274) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3216) [M::mem_pestat] mean and std.dev: (792.75, 713.13) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4187) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 863326 sequences (100000026 bp) in 2.640 CPU sec, 2.647 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 291810, 62, 84) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (250, 644, 1176) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3028) [M::mem_pestat] mean and std.dev: (658.40, 547.53) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3954) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (91, 117, 153) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 277) [M::mem_pestat] mean and std.dev: (124.67, 45.55) [M::mem_pestat] low and high boundaries for proper pairs: (1, 339) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (179, 617, 1419) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3899) [M::mem_pestat] mean and std.dev: (898.28, 898.54) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5139) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (246, 666, 1502) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4014) [M::mem_pestat] mean and std.dev: (816.42, 727.22) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5270) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 865438 reads in 400.348 CPU sec, 12.807 real sec [M::mem_process_seqs] Processed 863846 reads in 465.289 CPU sec, 14.924 real sec sorting block 11, #reads = 1050649 mem = 536896520 peak = 912162816 [M::process] read 861292 sequences (100000084 bp) in 3.671 CPU sec, 3.865 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 291087, 60, 85) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (239, 516, 1219) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3179) [M::mem_pestat] mean and std.dev: (759.17, 723.16) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4159) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (90, 116, 152) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 276) [M::mem_pestat] mean and std.dev: (124.08, 45.25) [M::mem_pestat] low and high boundaries for proper pairs: (1, 338) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (285, 723, 1807) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4851) [M::mem_pestat] mean and std.dev: (1007.11, 968.57) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6373) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (239, 482, 1182) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3068) [M::mem_pestat] mean and std.dev: (684.50, 677.20) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4011) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 864430 sequences (100000055 bp) in 2.120 CPU sec, 2.124 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (88, 292204, 68, 68) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (159, 403, 1109) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3009) [M::mem_pestat] mean and std.dev: (599.16, 648.99) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3959) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (91, 117, 153) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 277) [M::mem_pestat] mean and std.dev: (124.60, 45.59) [M::mem_pestat] low and high boundaries for proper pairs: (1, 339) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (191, 585, 1180) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3158) [M::mem_pestat] mean and std.dev: (729.02, 680.53) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4147) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (169, 496, 1148) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3106) [M::mem_pestat] mean and std.dev: (703.90, 677.73) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4085) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 865236 reads in 431.558 CPU sec, 13.872 real sec sorting block 12, #reads = 1048502 mem = 536880833 peak = 912162816 [M::mem_process_seqs] Processed 863326 reads in 503.760 CPU sec, 16.236 real sec sorting block 13, #reads = 1044745 mem = 536888278 peak = 912162816 [M::process] read 867794 sequences (100000147 bp) in 3.633 CPU sec, 3.773 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (90, 290903, 74, 78) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (270, 656, 1283) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3309) [M::mem_pestat] mean and std.dev: (768.74, 658.34) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4322) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (91, 116, 153) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 277) [M::mem_pestat] mean and std.dev: (124.37, 45.40) [M::mem_pestat] low and high boundaries for proper pairs: (1, 339) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (210, 606, 1315) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3525) [M::mem_pestat] mean and std.dev: (896.44, 895.60) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4630) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (152, 372, 1127) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3077) [M::mem_pestat] mean and std.dev: (718.08, 739.20) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4052) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 865474 sequences (100000084 bp) in 2.520 CPU sec, 2.521 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (92, 290462, 50, 108) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (224, 480, 1356) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3620) [M::mem_pestat] mean and std.dev: (840.51, 829.67) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4752) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (91, 117, 154) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 280) [M::mem_pestat] mean and std.dev: (125.40, 46.19) [M::mem_pestat] low and high boundaries for proper pairs: (1, 343) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (168, 360, 1190) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3234) [M::mem_pestat] mean and std.dev: (764.29, 855.54) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4256) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (223, 465, 1061) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2737) [M::mem_pestat] mean and std.dev: (655.05, 573.84) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3575) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 864430 reads in 430.085 CPU sec, 13.776 real sec sorting block 14, #reads = 1049127 mem = 536883589 peak = 912162816 [M::mem_process_seqs] Processed 861292 reads in 501.002 CPU sec, 16.109 real sec [M::process] read 865224 sequences (100000125 bp) in 3.526 CPU sec, 3.679 real sec... sorting block 15, #reads = 1046859 mem = 536881049 peak = 912162816 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (103, 291858, 70, 75) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (205, 424, 1024) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2662) [M::mem_pestat] mean and std.dev: (642.35, 598.08) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3481) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (90, 116, 152) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 276) [M::mem_pestat] mean and std.dev: (123.73, 45.11) [M::mem_pestat] low and high boundaries for proper pairs: (1, 338) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (209, 748, 1501) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4085) [M::mem_pestat] mean and std.dev: (819.53, 868.22) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5377) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (171, 438, 1071) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2871) [M::mem_pestat] mean and std.dev: (628.38, 657.12) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3771) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 864984 sequences (100000067 bp) in 2.652 CPU sec, 2.661 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (84, 291789, 63, 79) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (231, 576, 1216) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3186) [M::mem_pestat] mean and std.dev: (752.26, 752.07) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4171) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (91, 116, 153) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 277) [M::mem_pestat] mean and std.dev: (124.20, 45.34) [M::mem_pestat] low and high boundaries for proper pairs: (1, 339) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (153, 384, 1133) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3093) [M::mem_pestat] mean and std.dev: (641.52, 704.02) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4073) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (163, 388, 848) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2218) [M::mem_pestat] mean and std.dev: (523.40, 511.38) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2903) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 867794 reads in 419.516 CPU sec, 13.431 real sec [M::process] read 862892 sequences (100000034 bp) in 2.784 CPU sec, 2.791 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 292749, 54, 64) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (147, 325, 994) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2688) [M::mem_pestat] mean and std.dev: (557.47, 614.31) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3535) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (91, 116, 153) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 277) [M::mem_pestat] mean and std.dev: (124.37, 45.40) [M::mem_pestat] low and high boundaries for proper pairs: (1, 339) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (151, 725, 1772) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5014) [M::mem_pestat] mean and std.dev: (948.66, 1043.54) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6635) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (251, 723, 1627) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4379) [M::mem_pestat] mean and std.dev: (985.89, 961.18) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5755) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 865224 reads in 249.999 CPU sec, 8.303 real sec sorting block 16, #reads = 1047696 mem = 536888716 peak = 912162816 [M::mem_process_seqs] Processed 865474 reads in 789.095 CPU sec, 25.649 real sec sorting block 17, #reads = 1051297 mem = 536878486 peak = 942628864 [M::process] read 863804 sequences (100000093 bp) in 4.115 CPU sec, 4.291 real sec... [M::process] read 862064 sequences (100000114 bp) in 2.249 CPU sec, 2.254 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 291296, 57, 66) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (260, 618, 1385) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3635) [M::mem_pestat] mean and std.dev: (861.23, 733.55) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4760) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (91, 117, 153) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 277) [M::mem_pestat] mean and std.dev: (124.64, 45.52) [M::mem_pestat] low and high boundaries for proper pairs: (1, 339) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (265, 796, 1803) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4879) [M::mem_pestat] mean and std.dev: (888.92, 847.49) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6417) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (180, 345, 674) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1662) [M::mem_pestat] mean and std.dev: (424.98, 355.25) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2156) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 862892 reads in 238.793 CPU sec, 7.697 real sec sorting block 18, #reads = 1050793 mem = 536881960 peak = 942628864 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 291544, 52, 92) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (178, 428, 1488) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4108) [M::mem_pestat] mean and std.dev: (744.88, 885.89) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5418) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (90, 116, 153) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 279) [M::mem_pestat] mean and std.dev: (124.47, 45.59) [M::mem_pestat] low and high boundaries for proper pairs: (1, 342) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (251, 617, 1040) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2618) [M::mem_pestat] mean and std.dev: (728.43, 593.88) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3407) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (199, 706, 1131) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2995) [M::mem_pestat] mean and std.dev: (635.48, 526.58) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3927) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 861242 sequences (100000156 bp) in 3.453 CPU sec, 3.475 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 290618, 64, 78) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (220, 461, 1072) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2776) [M::mem_pestat] mean and std.dev: (609.29, 522.76) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3628) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (91, 116, 153) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 277) [M::mem_pestat] mean and std.dev: (124.55, 45.44) [M::mem_pestat] low and high boundaries for proper pairs: (1, 339) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (233, 647, 2072) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5750) [M::mem_pestat] mean and std.dev: (992.80, 1093.32) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7589) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (190, 428, 985) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2575) [M::mem_pestat] mean and std.dev: (560.93, 518.14) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3370) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 864984 reads in 726.520 CPU sec, 23.337 real sec sorting block 19, #reads = 1047334 mem = 536887647 peak = 942628864 [M::mem_process_seqs] Processed 863804 reads in 386.496 CPU sec, 12.514 real sec sorting block 20, #reads = 1045165 mem = 536887916 peak = 942628864 [M::process] read 861726 sequences (100000035 bp) in 3.785 CPU sec, 3.913 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 290563, 61, 83) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (181, 510, 1194) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3220) [M::mem_pestat] mean and std.dev: (692.83, 679.12) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4233) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (91, 117, 154) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 280) [M::mem_pestat] mean and std.dev: (125.22, 45.88) [M::mem_pestat] low and high boundaries for proper pairs: (1, 343) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (250, 582, 1359) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3577) [M::mem_pestat] mean and std.dev: (921.29, 875.25) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4686) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (274, 715, 1518) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4006) [M::mem_pestat] mean and std.dev: (841.86, 703.49) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5250) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 866060 sequences (100000119 bp) in 2.278 CPU sec, 2.285 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (96, 290796, 70, 83) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (156, 421, 1024) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2760) [M::mem_pestat] mean and std.dev: (610.76, 671.09) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3628) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (91, 117, 153) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 277) [M::mem_pestat] mean and std.dev: (124.83, 45.50) [M::mem_pestat] low and high boundaries for proper pairs: (1, 339) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (275, 603, 2011) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5483) [M::mem_pestat] mean and std.dev: (1039.95, 1305.22) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7219) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (187, 468, 1692) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4702) [M::mem_pestat] mean and std.dev: (940.90, 1022.64) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6207) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 861242 reads in 408.589 CPU sec, 13.071 real sec sorting block 21, #reads = 1047897 mem = 536886682 peak = 942628864 [M::mem_process_seqs] Processed 862064 reads in 478.809 CPU sec, 15.344 real sec [M::process] read 864584 sequences (100000046 bp) in 4.474 CPU sec, 4.643 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 290694, 54, 104) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (176, 400, 963) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2537) [M::mem_pestat] mean and std.dev: (528.19, 515.12) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3324) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (91, 117, 154) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 280) [M::mem_pestat] mean and std.dev: (125.07, 45.91) [M::mem_pestat] low and high boundaries for proper pairs: (1, 343) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (134, 460, 1028) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2816) [M::mem_pestat] mean and std.dev: (547.98, 521.74) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3710) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (236, 457, 1092) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2804) [M::mem_pestat] mean and std.dev: (660.34, 611.88) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3660) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 863410 sequences (100000084 bp) in 2.105 CPU sec, 2.108 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (79, 291774, 49, 64) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (191, 514, 1331) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3611) [M::mem_pestat] mean and std.dev: (814.35, 841.04) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4751) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (90, 116, 152) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 276) [M::mem_pestat] mean and std.dev: (123.93, 45.19) [M::mem_pestat] low and high boundaries for proper pairs: (1, 338) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (190, 514, 1923) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5389) [M::mem_pestat] mean and std.dev: (1192.48, 1417.41) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7122) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (206, 366, 1107) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2909) [M::mem_pestat] mean and std.dev: (667.13, 690.87) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3810) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 861726 reads in 400.557 CPU sec, 12.828 real sec sorting block 22, #reads = 1047361 mem = 536884999 peak = 942628864 [M::mem_process_seqs] Processed 866060 reads in 468.642 CPU sec, 15.036 real sec sorting block 23, #reads = 1045016 mem = 536895229 peak = 942628864 [M::process] read 864506 sequences (100000098 bp) in 3.086 CPU sec, 3.183 real sec... [M::process] read 863050 sequences (100000086 bp) in 2.325 CPU sec, 2.327 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 292149, 71, 68) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (267, 457, 1028) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2550) [M::mem_pestat] mean and std.dev: (642.70, 579.56) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3311) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (91, 117, 153) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 277) [M::mem_pestat] mean and std.dev: (124.61, 45.51) [M::mem_pestat] low and high boundaries for proper pairs: (1, 339) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (198, 533, 1435) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3909) [M::mem_pestat] mean and std.dev: (734.22, 683.53) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5146) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (319, 864, 1509) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3889) [M::mem_pestat] mean and std.dev: (1031.17, 910.64) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5079) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (84, 291565, 55, 83) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (290, 534, 1556) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4088) [M::mem_pestat] mean and std.dev: (921.74, 899.80) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5354) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (91, 116, 153) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 277) [M::mem_pestat] mean and std.dev: (124.28, 45.35) [M::mem_pestat] low and high boundaries for proper pairs: (1, 339) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (324, 515, 1119) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2709) [M::mem_pestat] mean and std.dev: (684.36, 549.47) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3504) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (312, 563, 1455) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3741) [M::mem_pestat] mean and std.dev: (806.50, 784.48) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4884) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 863410 reads in 395.614 CPU sec, 12.663 real sec sorting block 24, #reads = 1052852 mem = 536889873 peak = 942628864 [M::mem_process_seqs] Processed 864584 reads in 464.454 CPU sec, 14.960 real sec sorting block 25, #reads = 1050230 mem = 536885983 peak = 942628864 [M::process] read 862462 sequences (100000016 bp) in 3.930 CPU sec, 4.128 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (88, 292134, 59, 60) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (156, 402, 951) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2541) [M::mem_pestat] mean and std.dev: (520.03, 513.49) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3336) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (91, 117, 153) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 277) [M::mem_pestat] mean and std.dev: (124.46, 45.45) [M::mem_pestat] low and high boundaries for proper pairs: (1, 339) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (144, 594, 1676) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4740) [M::mem_pestat] mean and std.dev: (959.52, 1121.68) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6272) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (215, 585, 1190) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3140) [M::mem_pestat] mean and std.dev: (677.43, 581.22) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4115) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 862118 sequences (100000016 bp) in 2.404 CPU sec, 2.415 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 290928, 49, 90) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (211, 473, 1520) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4138) [M::mem_pestat] mean and std.dev: (766.12, 849.61) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5447) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (91, 117, 153) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 277) [M::mem_pestat] mean and std.dev: (124.70, 45.52) [M::mem_pestat] low and high boundaries for proper pairs: (1, 339) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (194, 578, 2071) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5825) [M::mem_pestat] mean and std.dev: (1164.81, 1472.94) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7702) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (220, 567, 1325) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3535) [M::mem_pestat] mean and std.dev: (794.27, 732.46) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4640) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 291320, 69, 87) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (173, 439, 1450) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4004) [M::mem_pestat] mean and std.dev: (678.18, 676.15) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5281) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (91, 117, 153) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 277) [M::mem_pestat] mean and std.dev: (124.72, 45.50) [M::mem_pestat] low and high boundaries for proper pairs: (1, 339) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (196, 490, 1123) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2977) [M::mem_pestat] mean and std.dev: (645.17, 596.31) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3904) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (186, 351, 1243) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3357) [M::mem_pestat] mean and std.dev: (709.94, 694.12) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4414) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 864506 reads in 594.163 CPU sec, 19.095 real sec sorting block 26, #reads = 1051870 mem = 536890323 peak = 942628864 [M::mem_process_seqs] Processed 863050 reads in 478.160 CPU sec, 15.438 real sec [M::mem_process_seqs] Processed 862462 reads in 547.222 CPU sec, 17.683 real sec [M::process] read 861730 sequences (100000105 bp) in 3.555 CPU sec, 3.658 real sec... sorting block 27, #reads = 1049603 mem = 536885761 peak = 942628864 [M::process] read 860834 sequences (100000091 bp) in 3.276 CPU sec, 3.484 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (91, 291153, 57, 83) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (173, 543, 1262) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3440) [M::mem_pestat] mean and std.dev: (719.97, 678.25) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4529) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (91, 117, 154) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 280) [M::mem_pestat] mean and std.dev: (125.10, 45.90) [M::mem_pestat] low and high boundaries for proper pairs: (1, 343) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (270, 681, 1680) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4500) [M::mem_pestat] mean and std.dev: (908.24, 825.01) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5910) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (199, 423, 1391) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3775) [M::mem_pestat] mean and std.dev: (675.44, 694.68) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4967) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 868498 sequences (100000147 bp) in 2.356 CPU sec, 2.366 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 290637, 62, 87) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (198, 531, 1216) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3252) [M::mem_pestat] mean and std.dev: (785.68, 778.08) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4270) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (91, 117, 154) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 280) [M::mem_pestat] mean and std.dev: (125.14, 45.86) [M::mem_pestat] low and high boundaries for proper pairs: (1, 343) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (299, 710, 1318) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3356) [M::mem_pestat] mean and std.dev: (698.30, 587.26) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4375) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (310, 545, 1242) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3106) [M::mem_pestat] mean and std.dev: (787.00, 801.80) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4038) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 862118 reads in 424.463 CPU sec, 13.654 real sec sorting block 28, #reads = 1048540 mem = 536880627 peak = 942628864 [M::mem_process_seqs] Processed 861730 reads in 304.024 CPU sec, 9.807 real sec sorting block 29, #reads = 1051312 mem = 536878324 peak = 948707328 [M::process] read 872602 sequences (100000134 bp) in 3.164 CPU sec, 3.318 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (88, 290642, 78, 77) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (200, 396, 945) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2435) [M::mem_pestat] mean and std.dev: (626.50, 594.04) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3180) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (91, 117, 154) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 280) [M::mem_pestat] mean and std.dev: (125.38, 46.04) [M::mem_pestat] low and high boundaries for proper pairs: (1, 343) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (245, 930, 1971) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5423) [M::mem_pestat] mean and std.dev: (1221.05, 1341.51) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7149) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (193, 404, 1083) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2863) [M::mem_pestat] mean and std.dev: (590.43, 554.52) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3753) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 870410 sequences (100000017 bp) in 2.467 CPU sec, 2.476 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 293062, 66, 81) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (223, 424, 1308) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3478) [M::mem_pestat] mean and std.dev: (713.33, 778.43) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4563) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (90, 115, 150) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 270) [M::mem_pestat] mean and std.dev: (122.33, 43.88) [M::mem_pestat] low and high boundaries for proper pairs: (1, 330) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (103, 554, 959) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2671) [M::mem_pestat] mean and std.dev: (500.17, 521.22) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3527) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (200, 613, 1178) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3134) [M::mem_pestat] mean and std.dev: (728.34, 649.50) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4112) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 292419, 56, 75) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (277, 692, 1177) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2977) [M::mem_pestat] mean and std.dev: (764.86, 626.78) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3877) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (90, 116, 151) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 273) [M::mem_pestat] mean and std.dev: (123.29, 44.54) [M::mem_pestat] low and high boundaries for proper pairs: (1, 334) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (212, 475, 1085) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2831) [M::mem_pestat] mean and std.dev: (549.41, 553.40) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3704) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (194, 538, 1475) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4037) [M::mem_pestat] mean and std.dev: (805.61, 794.64) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5318) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 860834 reads in 591.493 CPU sec, 19.131 real sec sorting block 30, #reads = 1048021 mem = 536891107 peak = 956420096 [M::mem_process_seqs] Processed 872602 reads in 481.673 CPU sec, 15.558 real sec [M::mem_process_seqs] Processed 868498 reads in 554.776 CPU sec, 17.923 real sec [M::process] read 871604 sequences (100000137 bp) in 3.003 CPU sec, 3.132 real sec... sorting block 31, #reads = 1046195 mem = 536901649 peak = 956420096 [M::process] read 872522 sequences (100000036 bp) in 3.170 CPU sec, 3.307 real sec... sorting block 32, #reads = 1048231 mem = 536888358 peak = 956420096 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 292981, 49, 78) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (178, 410, 1212) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3280) [M::mem_pestat] mean and std.dev: (778.55, 835.21) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4314) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (90, 115, 150) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 270) [M::mem_pestat] mean and std.dev: (122.69, 43.89) [M::mem_pestat] low and high boundaries for proper pairs: (1, 330) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (197, 869, 2196) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6194) [M::mem_pestat] mean and std.dev: (1331.23, 1475.13) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8193) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (225, 402, 901) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2253) [M::mem_pestat] mean and std.dev: (535.04, 466.39) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2929) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 870240 sequences (100000191 bp) in 2.253 CPU sec, 2.261 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (83, 293516, 53, 87) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (143, 319, 876) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2342) [M::mem_pestat] mean and std.dev: (470.97, 470.71) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3075) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (90, 115, 150) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 270) [M::mem_pestat] mean and std.dev: (122.48, 43.92) [M::mem_pestat] low and high boundaries for proper pairs: (1, 330) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (119, 400, 1579) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4499) [M::mem_pestat] mean and std.dev: (776.06, 776.80) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5959) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (186, 475, 1560) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4308) [M::mem_pestat] mean and std.dev: (888.91, 983.78) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5682) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 293063, 68, 69) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (325, 608, 1343) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3379) [M::mem_pestat] mean and std.dev: (799.23, 662.23) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4397) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (90, 115, 150) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 270) [M::mem_pestat] mean and std.dev: (122.41, 43.79) [M::mem_pestat] low and high boundaries for proper pairs: (1, 330) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (255, 503, 1136) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2898) [M::mem_pestat] mean and std.dev: (655.79, 603.25) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3779) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (206, 484, 974) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2510) [M::mem_pestat] mean and std.dev: (584.52, 502.96) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3278) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 870410 reads in 597.706 CPU sec, 19.223 real sec [M::mem_process_seqs] Processed 871604 reads in 491.892 CPU sec, 15.861 real sec sorting block 33, #reads = 1047457 mem = 536882618 peak = 956420096 [M::mem_process_seqs] Processed 872522 reads in 570.054 CPU sec, 18.362 real sec [M::process] read 871338 sequences (100000051 bp) in 3.140 CPU sec, 3.264 real sec... sorting block 34, #reads = 1046708 mem = 536884938 peak = 956420096 [M::process] read 867720 sequences (100000081 bp) in 3.078 CPU sec, 3.208 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 293493, 50, 96) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (204, 627, 1382) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3738) [M::mem_pestat] mean and std.dev: (844.70, 799.28) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4916) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (90, 115, 150) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 270) [M::mem_pestat] mean and std.dev: (122.80, 44.00) [M::mem_pestat] low and high boundaries for proper pairs: (1, 330) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (210, 815, 1837) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5091) [M::mem_pestat] mean and std.dev: (1095.73, 1114.45) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6718) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (239, 438, 1259) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3299) [M::mem_pestat] mean and std.dev: (753.64, 695.45) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4319) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 867550 sequences (100000076 bp) in 2.219 CPU sec, 2.226 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 292404, 64, 74) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (184, 454, 861) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2215) [M::mem_pestat] mean and std.dev: (570.92, 506.14) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2892) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (90, 115, 150) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 270) [M::mem_pestat] mean and std.dev: (122.56, 43.99) [M::mem_pestat] low and high boundaries for proper pairs: (1, 330) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (147, 703, 1809) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5133) [M::mem_pestat] mean and std.dev: (1029.38, 1163.02) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6795) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (216, 580, 1058) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2742) [M::mem_pestat] mean and std.dev: (707.14, 650.75) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3584) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (85, 291317, 67, 82) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (217, 464, 905) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2281) [M::mem_pestat] mean and std.dev: (583.31, 506.29) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2969) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (90, 116, 151) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 273) [M::mem_pestat] mean and std.dev: (123.35, 44.53) [M::mem_pestat] low and high boundaries for proper pairs: (1, 334) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (123, 529, 1513) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4293) [M::mem_pestat] mean and std.dev: (830.05, 905.40) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5683) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (247, 499, 1092) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2782) [M::mem_pestat] mean and std.dev: (707.73, 636.19) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3627) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 870240 reads in 611.281 CPU sec, 19.624 real sec sorting block 35, #reads = 1041775 mem = 536882197 peak = 956420096 [M::mem_process_seqs] Processed 871338 reads in 516.071 CPU sec, 16.628 real sec sorting block 36, #reads = 1037743 mem = 536888031 peak = 956420096 [M::process] read 876300 sequences (100000063 bp) in 3.662 CPU sec, 3.763 real sec... [M::mem_process_seqs] Processed 867720 reads in 595.306 CPU sec, 19.157 real sec sorting block 37, #reads = 1034843 mem = 536890382 peak = 956420096 [M::process] read 874420 sequences (100000098 bp) in 2.811 CPU sec, 2.932 real sec... [M::process] read 871446 sequences (100000082 bp) in 2.271 CPU sec, 2.277 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (79, 291453, 50, 66) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (210, 402, 796) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1968) [M::mem_pestat] mean and std.dev: (517.59, 405.92) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2554) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (90, 116, 151) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 273) [M::mem_pestat] mean and std.dev: (123.41, 44.52) [M::mem_pestat] low and high boundaries for proper pairs: (1, 334) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (422, 670, 1571) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3869) [M::mem_pestat] mean and std.dev: (911.56, 833.26) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5018) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (280, 544, 1270) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3250) [M::mem_pestat] mean and std.dev: (761.45, 706.72) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4240) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (97, 293007, 43, 76) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (181, 380, 987) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2599) [M::mem_pestat] mean and std.dev: (547.35, 532.44) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3405) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (90, 114, 149) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 267) [M::mem_pestat] mean and std.dev: (121.76, 43.25) [M::mem_pestat] low and high boundaries for proper pairs: (1, 326) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (254, 799, 1693) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4571) [M::mem_pestat] mean and std.dev: (994.15, 1069.63) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6010) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (193, 760, 1116) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2962) [M::mem_pestat] mean and std.dev: (755.86, 647.72) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3885) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (95, 292325, 49, 77) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (180, 450, 1213) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3279) [M::mem_pestat] mean and std.dev: (659.64, 753.69) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4312) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (89, 114, 148) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 266) [M::mem_pestat] mean and std.dev: (121.30, 43.09) [M::mem_pestat] low and high boundaries for proper pairs: (1, 325) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (169, 336, 1135) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3067) [M::mem_pestat] mean and std.dev: (626.04, 644.80) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4033) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (265, 527, 1476) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3898) [M::mem_pestat] mean and std.dev: (867.84, 901.17) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5109) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 867550 reads in 626.502 CPU sec, 20.378 real sec sorting block 38, #reads = 1035063 mem = 536885943 peak = 956420096 [M::mem_process_seqs] Processed 874420 reads in 521.476 CPU sec, 16.836 real sec [M::process] read 870062 sequences (100000043 bp) in 3.281 CPU sec, 3.378 real sec... [M::mem_process_seqs] Processed 876300 reads in 609.614 CPU sec, 19.652 real sec sorting block 39, #reads = 1033714 mem = 536897198 peak = 956420096 [M::process] read 870422 sequences (100000160 bp) in 3.181 CPU sec, 3.313 real sec... [M::process] read 870174 sequences (100000134 bp) in 2.121 CPU sec, 2.121 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 293404, 50, 65) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (160, 583, 1668) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4684) [M::mem_pestat] mean and std.dev: (933.88, 1049.93) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6192) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (90, 115, 150) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 270) [M::mem_pestat] mean and std.dev: (122.64, 43.92) [M::mem_pestat] low and high boundaries for proper pairs: (1, 330) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (173, 531, 1043) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2783) [M::mem_pestat] mean and std.dev: (527.89, 443.94) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3653) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (248, 437, 1102) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2810) [M::mem_pestat] mean and std.dev: (672.65, 587.15) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3664) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 293272, 53, 73) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (226, 599, 1669) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4555) [M::mem_pestat] mean and std.dev: (912.98, 959.23) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5998) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (90, 115, 151) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 273) [M::mem_pestat] mean and std.dev: (123.02, 44.34) [M::mem_pestat] low and high boundaries for proper pairs: (1, 334) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (228, 598, 1329) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3531) [M::mem_pestat] mean and std.dev: (713.37, 639.85) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4632) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (197, 517, 1281) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3449) [M::mem_pestat] mean and std.dev: (739.00, 647.74) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4533) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 871446 reads in 406.648 CPU sec, 13.011 real sec sorting block 40, #reads = 1026739 mem = 536878784 peak = 956420096 [M::mem_process_seqs] Processed 870062 reads in 465.248 CPU sec, 14.913 real sec sorting block 41, #reads = 1041743 mem = 536882740 peak = 956420096 [M::process] read 869158 sequences (100000269 bp) in 3.545 CPU sec, 3.652 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (89, 293032, 59, 72) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (174, 487, 1389) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3819) [M::mem_pestat] mean and std.dev: (735.73, 802.09) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5034) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (90, 115, 150) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 270) [M::mem_pestat] mean and std.dev: (122.70, 43.91) [M::mem_pestat] low and high boundaries for proper pairs: (1, 330) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (238, 434, 994) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2506) [M::mem_pestat] mean and std.dev: (645.25, 592.53) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3262) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (199, 475, 1085) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2857) [M::mem_pestat] mean and std.dev: (652.55, 692.68) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3743) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 865238 sequences (100000197 bp) in 2.350 CPU sec, 2.346 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 292728, 40, 81) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (233, 548, 1938) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5348) [M::mem_pestat] mean and std.dev: (1083.32, 1217.03) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7053) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (90, 115, 150) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 270) [M::mem_pestat] mean and std.dev: (122.76, 44.00) [M::mem_pestat] low and high boundaries for proper pairs: (1, 330) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (284, 726, 1537) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4043) [M::mem_pestat] mean and std.dev: (776.00, 672.55) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5296) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (224, 432, 1587) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4313) [M::mem_pestat] mean and std.dev: (951.49, 900.77) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5676) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 870422 reads in 388.189 CPU sec, 12.484 real sec sorting block 42, #reads = 1044849 mem = 536886725 peak = 956420096 [M::mem_process_seqs] Processed 870174 reads in 460.891 CPU sec, 14.827 real sec [M::process] read 865046 sequences (100000086 bp) in 2.821 CPU sec, 2.911 real sec... sorting block 43, #reads = 1044236 mem = 536891426 peak = 956420096 [M::process] read 870876 sequences (100000104 bp) in 1.906 CPU sec, 1.913 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 290989, 50, 83) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (177, 375, 1399) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3843) [M::mem_pestat] mean and std.dev: (836.62, 876.64) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5065) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (90, 115, 151) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 273) [M::mem_pestat] mean and std.dev: (123.10, 44.41) [M::mem_pestat] low and high boundaries for proper pairs: (1, 334) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (257, 597, 1381) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3629) [M::mem_pestat] mean and std.dev: (858.38, 839.44) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4753) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (186, 612, 1256) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3396) [M::mem_pestat] mean and std.dev: (665.01, 639.56) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4466) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 291447, 56, 97) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (180, 336, 1190) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3210) [M::mem_pestat] mean and std.dev: (619.51, 654.93) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4220) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (91, 116, 152) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 274) [M::mem_pestat] mean and std.dev: (123.83, 44.70) [M::mem_pestat] low and high boundaries for proper pairs: (1, 335) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (205, 478, 1497) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4081) [M::mem_pestat] mean and std.dev: (855.48, 870.51) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5373) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (223, 492, 1282) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3400) [M::mem_pestat] mean and std.dev: (733.71, 730.36) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4459) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (92, 291033, 56, 88) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (194, 676, 1595) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4397) [M::mem_pestat] mean and std.dev: (852.95, 804.23) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5798) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (91, 116, 152) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 274) [M::mem_pestat] mean and std.dev: (123.92, 44.80) [M::mem_pestat] low and high boundaries for proper pairs: (1, 335) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (352, 795, 1950) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5146) [M::mem_pestat] mean and std.dev: (1201.30, 1282.29) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6744) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (187, 405, 988) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2590) [M::mem_pestat] mean and std.dev: (602.15, 574.26) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3391) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 869158 reads in 560.072 CPU sec, 17.984 real sec sorting block 44, #reads = 1028607 mem = 536875173 peak = 956420096 [M::mem_process_seqs] Processed 865238 reads in 444.614 CPU sec, 14.377 real sec [M::mem_process_seqs] Processed 865046 reads in 507.880 CPU sec, 16.407 real sec sorting block 45, #reads = 1046102 mem = 536890905 peak = 956420096 [M::process] read 869866 sequences (100000038 bp) in 3.152 CPU sec, 3.259 real sec... [M::process] read 867698 sequences (100000010 bp) in 2.945 CPU sec, 3.061 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (81, 291894, 55, 75) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (186, 334, 874) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2250) [M::mem_pestat] mean and std.dev: (453.92, 400.69) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2938) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (90, 115, 150) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 270) [M::mem_pestat] mean and std.dev: (122.55, 43.87) [M::mem_pestat] low and high boundaries for proper pairs: (1, 330) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (210, 479, 1128) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2964) [M::mem_pestat] mean and std.dev: (715.57, 718.16) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3882) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (192, 535, 1290) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3486) [M::mem_pestat] mean and std.dev: (765.64, 675.35) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4584) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 869390 sequences (100000178 bp) in 2.060 CPU sec, 2.059 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 292907, 73, 75) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (220, 520, 1241) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3283) [M::mem_pestat] mean and std.dev: (676.54, 621.69) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4304) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (90, 115, 150) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 270) [M::mem_pestat] mean and std.dev: (122.80, 43.99) [M::mem_pestat] low and high boundaries for proper pairs: (1, 330) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (263, 566, 1841) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4997) [M::mem_pestat] mean and std.dev: (1047.64, 1157.70) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6575) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (212, 418, 1141) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2999) [M::mem_pestat] mean and std.dev: (680.80, 650.71) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3928) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 293080, 39, 74) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (185, 707, 1464) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4022) [M::mem_pestat] mean and std.dev: (857.11, 809.86) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5301) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (90, 116, 151) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 273) [M::mem_pestat] mean and std.dev: (123.58, 44.62) [M::mem_pestat] low and high boundaries for proper pairs: (1, 334) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (109, 585, 1540) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4402) [M::mem_pestat] mean and std.dev: (864.63, 1051.23) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5833) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (238, 427, 1314) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3466) [M::mem_pestat] mean and std.dev: (716.27, 778.70) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4542) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 870876 reads in 494.613 CPU sec, 15.865 real sec sorting block 46, #reads = 1037410 mem = 536889331 peak = 956420096 [M::mem_process_seqs] Processed 869866 reads in 392.069 CPU sec, 12.616 real sec sorting block 47, #reads = 1041686 mem = 536886184 peak = 1039249408 [M::mem_process_seqs] Processed 867698 reads in 446.803 CPU sec, 14.369 real sec [M::process] read 868338 sequences (100000049 bp) in 2.627 CPU sec, 2.719 real sec... sorting block 48, #reads = 1047815 mem = 536885901 peak = 1039249408 [M::process] read 866356 sequences (100000159 bp) in 2.430 CPU sec, 2.547 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (94, 293694, 50, 82) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (242, 449, 1424) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3788) [M::mem_pestat] mean and std.dev: (888.08, 954.68) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4970) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (90, 115, 151) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 273) [M::mem_pestat] mean and std.dev: (123.17, 44.47) [M::mem_pestat] low and high boundaries for proper pairs: (1, 334) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (240, 702, 1248) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3264) [M::mem_pestat] mean and std.dev: (747.96, 701.79) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4272) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (282, 643, 1363) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3525) [M::mem_pestat] mean and std.dev: (837.39, 764.01) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4606) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 865534 sequences (100000183 bp) in 1.669 CPU sec, 1.677 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (91, 293268, 56, 76) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (183, 425, 1201) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3237) [M::mem_pestat] mean and std.dev: (698.10, 736.70) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4255) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (90, 116, 151) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 273) [M::mem_pestat] mean and std.dev: (123.28, 44.38) [M::mem_pestat] low and high boundaries for proper pairs: (1, 334) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (223, 488, 1309) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3481) [M::mem_pestat] mean and std.dev: (721.31, 772.49) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4567) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (199, 402, 1101) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2905) [M::mem_pestat] mean and std.dev: (602.10, 576.88) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3807) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 291879, 52, 84) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (199, 495, 1261) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3385) [M::mem_pestat] mean and std.dev: (675.17, 576.35) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4447) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (90, 116, 152) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 276) [M::mem_pestat] mean and std.dev: (123.93, 44.99) [M::mem_pestat] low and high boundaries for proper pairs: (1, 338) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (242, 531, 2315) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6461) [M::mem_pestat] mean and std.dev: (989.24, 1134.97) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8534) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (221, 466, 1552) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4214) [M::mem_pestat] mean and std.dev: (897.22, 942.56) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5545) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 869390 reads in 455.033 CPU sec, 14.611 real sec sorting block 49, #reads = 1051271 mem = 536877850 peak = 1039249408 [M::mem_process_seqs] Processed 868338 reads in 369.065 CPU sec, 11.913 real sec [M::mem_process_seqs] Processed 866356 reads in 431.269 CPU sec, 13.906 real sec sorting block 50, #reads = 1048582 mem = 536887957 peak = 1039249408 [M::process] read 864962 sequences (100000301 bp) in 3.378 CPU sec, 3.477 real sec... [M::process] read 864648 sequences (100000145 bp) in 2.994 CPU sec, 3.134 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 290829, 53, 76) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (210, 532, 1600) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4380) [M::mem_pestat] mean and std.dev: (844.14, 830.22) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5770) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (91, 116, 152) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 274) [M::mem_pestat] mean and std.dev: (123.94, 44.75) [M::mem_pestat] low and high boundaries for proper pairs: (1, 335) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (170, 361, 1276) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3488) [M::mem_pestat] mean and std.dev: (597.48, 720.41) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4594) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (257, 555, 1127) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2867) [M::mem_pestat] mean and std.dev: (727.33, 634.22) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3737) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 871128 sequences (100000204 bp) in 1.940 CPU sec, 1.945 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (91, 291403, 59, 91) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (155, 368, 1242) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3416) [M::mem_pestat] mean and std.dev: (727.94, 817.96) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4503) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (91, 116, 152) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 274) [M::mem_pestat] mean and std.dev: (123.96, 44.72) [M::mem_pestat] low and high boundaries for proper pairs: (1, 335) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (230, 586, 1446) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3878) [M::mem_pestat] mean and std.dev: (894.39, 996.20) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5094) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (213, 641, 1609) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4401) [M::mem_pestat] mean and std.dev: (866.53, 855.45) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5797) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 290834, 81, 75) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (167, 380, 1194) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3248) [M::mem_pestat] mean and std.dev: (688.00, 803.42) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4275) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (91, 116, 152) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 274) [M::mem_pestat] mean and std.dev: (124.01, 44.80) [M::mem_pestat] low and high boundaries for proper pairs: (1, 335) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (167, 474, 1570) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4376) [M::mem_pestat] mean and std.dev: (756.74, 885.46) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5779) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (195, 455, 910) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2340) [M::mem_pestat] mean and std.dev: (571.32, 525.42) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3055) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 865534 reads in 513.571 CPU sec, 16.465 real sec sorting block 51, #reads = 1048866 mem = 536881193 peak = 1039249408 [M::mem_process_seqs] Processed 864962 reads in 412.332 CPU sec, 13.281 real sec sorting block 52, #reads = 1040969 mem = 536886177 peak = 1056432128 [M::mem_process_seqs] Processed 864648 reads in 477.888 CPU sec, 15.377 real sec [M::process] read 871222 sequences (100000111 bp) in 3.383 CPU sec, 3.489 real sec... sorting block 53, #reads = 1043723 mem = 536891623 peak = 1056432128 [M::process] read 869328 sequences (100000079 bp) in 2.898 CPU sec, 3.025 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 291467, 64, 86) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (257, 619, 1129) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2873) [M::mem_pestat] mean and std.dev: (592.34, 473.40) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3745) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (90, 115, 150) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 270) [M::mem_pestat] mean and std.dev: (122.68, 43.94) [M::mem_pestat] low and high boundaries for proper pairs: (1, 330) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (258, 703, 1340) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3504) [M::mem_pestat] mean and std.dev: (784.35, 652.15) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4586) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (223, 560, 1181) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3097) [M::mem_pestat] mean and std.dev: (786.76, 756.76) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4055) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 867842 sequences (100000013 bp) in 2.255 CPU sec, 2.261 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 292723, 49, 79) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (140, 322, 809) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2147) [M::mem_pestat] mean and std.dev: (429.10, 426.19) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2816) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (90, 115, 150) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 270) [M::mem_pestat] mean and std.dev: (122.59, 43.87) [M::mem_pestat] low and high boundaries for proper pairs: (1, 330) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (200, 379, 1504) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4112) [M::mem_pestat] mean and std.dev: (860.73, 927.63) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5416) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (272, 539, 1365) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3551) [M::mem_pestat] mean and std.dev: (903.65, 932.72) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4644) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (104, 292500, 56, 76) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (236, 502, 1139) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2945) [M::mem_pestat] mean and std.dev: (586.17, 518.00) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3848) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (90, 116, 151) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 273) [M::mem_pestat] mean and std.dev: (123.19, 44.46) [M::mem_pestat] low and high boundaries for proper pairs: (1, 334) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (244, 567, 1903) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5221) [M::mem_pestat] mean and std.dev: (924.25, 880.77) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6880) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (203, 376, 887) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2255) [M::mem_pestat] mean and std.dev: (532.46, 484.01) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2939) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 871128 reads in 542.258 CPU sec, 17.388 real sec sorting block 54, #reads = 1030792 mem = 536883287 peak = 1056432128 [M::mem_process_seqs] Processed 871222 reads in 438.507 CPU sec, 14.131 real sec sorting block 55, #reads = 1036073 mem = 536880844 peak = 1056432128 [M::mem_process_seqs] Processed 869328 reads in 505.172 CPU sec, 16.259 real sec [M::process] read 865984 sequences (100000126 bp) in 3.650 CPU sec, 3.749 real sec... [M::process] read 862472 sequences (100000291 bp) in 2.774 CPU sec, 2.889 real sec... sorting block 56, #reads = 1041071 mem = 536886658 peak = 1056432128 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (83, 292819, 54, 63) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (210, 412, 1194) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3162) [M::mem_pestat] mean and std.dev: (642.95, 616.68) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4146) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (90, 116, 151) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 273) [M::mem_pestat] mean and std.dev: (123.45, 44.51) [M::mem_pestat] low and high boundaries for proper pairs: (1, 334) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (181, 547, 1001) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2641) [M::mem_pestat] mean and std.dev: (618.78, 578.27) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3461) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (214, 346, 793) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1951) [M::mem_pestat] mean and std.dev: (471.21, 410.71) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2530) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 861180 sequences (100000090 bp) in 2.042 CPU sec, 2.047 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 290929, 62, 72) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (303, 904, 1491) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3867) [M::mem_pestat] mean and std.dev: (966.95, 841.83) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5055) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (90, 116, 152) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 276) [M::mem_pestat] mean and std.dev: (124.07, 45.15) [M::mem_pestat] low and high boundaries for proper pairs: (1, 338) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (171, 594, 1252) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3414) [M::mem_pestat] mean and std.dev: (756.60, 731.77) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4495) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (209, 469, 1270) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3392) [M::mem_pestat] mean and std.dev: (667.70, 677.03) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4453) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (92, 289370, 60, 81) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (215, 598, 1323) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3539) [M::mem_pestat] mean and std.dev: (787.42, 738.48) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4647) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (91, 117, 153) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 277) [M::mem_pestat] mean and std.dev: (124.68, 45.41) [M::mem_pestat] low and high boundaries for proper pairs: (1, 339) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (171, 413, 1956) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5526) [M::mem_pestat] mean and std.dev: (1014.86, 1298.18) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7311) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (227, 382, 838) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2060) [M::mem_pestat] mean and std.dev: (481.42, 444.35) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2671) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 867842 reads in 543.463 CPU sec, 17.434 real sec [M::mem_process_seqs] Processed 865984 reads in 448.932 CPU sec, 14.487 real sec sorting block 57, #reads = 1050811 mem = 536884535 peak = 1056432128 [M::mem_process_seqs] Processed 862472 reads in 521.277 CPU sec, 16.799 real sec [M::process] read 860302 sequences (100000166 bp) in 3.434 CPU sec, 3.549 real sec... sorting block 58, #reads = 1040411 mem = 536882350 peak = 1056432128 [M::process] read 860600 sequences (100000052 bp) in 3.171 CPU sec, 3.328 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (85, 289183, 61, 93) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (220, 443, 1492) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4036) [M::mem_pestat] mean and std.dev: (761.66, 740.46) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5308) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (91, 117, 154) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 280) [M::mem_pestat] mean and std.dev: (125.30, 45.95) [M::mem_pestat] low and high boundaries for proper pairs: (1, 343) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (211, 581, 1557) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4249) [M::mem_pestat] mean and std.dev: (803.88, 919.32) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5595) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (223, 584, 1151) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3007) [M::mem_pestat] mean and std.dev: (737.83, 692.95) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3935) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 454608 sequences (52737292 bp) in 1.600 CPU sec, 1.605 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 290041, 72, 85) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (184, 469, 1219) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3289) [M::mem_pestat] mean and std.dev: (668.29, 718.66) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4324) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (91, 117, 154) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 280) [M::mem_pestat] mean and std.dev: (125.46, 45.99) [M::mem_pestat] low and high boundaries for proper pairs: (1, 343) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (299, 582, 1424) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3674) [M::mem_pestat] mean and std.dev: (835.11, 780.83) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4799) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (343, 711, 1584) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4066) [M::mem_pestat] mean and std.dev: (1026.09, 909.51) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5307) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 289588, 69, 93) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (294, 522, 1402) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3618) [M::mem_pestat] mean and std.dev: (794.34, 842.63) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4726) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (91, 117, 154) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 280) [M::mem_pestat] mean and std.dev: (125.33, 45.80) [M::mem_pestat] low and high boundaries for proper pairs: (1, 343) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (298, 755, 1415) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3649) [M::mem_pestat] mean and std.dev: (823.30, 757.83) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4766) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (233, 555, 1518) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4088) [M::mem_pestat] mean and std.dev: (920.11, 862.38) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5373) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 861180 reads in 568.940 CPU sec, 18.285 real sec sorting block 59, #reads = 1041497 mem = 536891961 peak = 1056432128 [M::mem_process_seqs] Processed 860600 reads in 460.483 CPU sec, 14.892 real sec sorting block 60, #reads = 1045585 mem = 536899180 peak = 1056432128 [M::mem_process_seqs] Processed 860302 reads in 548.254 CPU sec, 17.762 real sec sorting block 61, #reads = 1043381 mem = 536882883 peak = 1056432128 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 153174, 30, 60) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (279, 764, 1068) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2646) [M::mem_pestat] mean and std.dev: (714.38, 550.02) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3435) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (91, 117, 153) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 277) [M::mem_pestat] mean and std.dev: (124.87, 45.46) [M::mem_pestat] low and high boundaries for proper pairs: (1, 339) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (192, 357, 1473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4035) [M::mem_pestat] mean and std.dev: (826.71, 1061.30) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5316) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (229, 558, 1635) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4447) [M::mem_pestat] mean and std.dev: (778.93, 777.99) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5853) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 454608 reads in 129.861 CPU sec, 4.263 real sec os version: Linux 6.12.88 cpu vendor: GenuineIntel signature: 000a06d1 features: bfebfbff 7ffefbff extended: f3bfb7ef fb417ffe amd bits: 2c100800 00000121 brand: Intel(R) Xeon(R) 6975P-C threads: 31 algo: bwa-mem license: sentieon:klib=31 reads: 63698432 overall: 77560602624 mem 18812.404 user 404.977 sys 637.761 real [main] Version: 0.7.17-r1188 [main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1029_BCAN-T1-TDNA-1_A23MHWWLT4_1.L001\tPU:L001\tSM:1029_BCAN-T1-TDNA-1_A23MHWWLT4_1\tLB:1029_BCAN-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1029_BCAN-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1029_BCAN-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz [main] Real time: 637.811 sec; CPU: 19217.397 sec sorting block 62, #reads = 688932 mem = 354904988 peak = 1056432128 uniq header count 1 merging 63 blocks sw version: sentieon-genomics-202308.03 os version: Linux 6.12.88 cpu vendor: GenuineIntel signature: 000a06d1 features: bfebfbff 7ffefbff extended: f3bfb7ef fb417ffe amd bits: 2c100800 00000121 brand: Intel(R) Xeon(R) 6975P-C threads: 31 max 192 algo: util-sort license: sentieon:util=1 output file size: 4807128141 output reads: 65508313 bam_mem_sort: 63 calls 37.219 user 0.881 sys 38.315 real bam_write: 63 calls 35.195 user 1.967 sys 44.359 real execute: 1 calls 21.018 user 1.538 sys 666.042 real merge_files: 1 calls 20.993 user 1.510 sys 27.772 real parse_chunk: 1003 calls 43.972 user 10.817 sys 56.868 real read_chunk: 2779 calls 24.304 user 19.009 sys 561.356 real sort_block: 1 calls 15.327 user 18.455 sys 549.273 real write_chunk: 1774 calls 20.302 user 1.098 sys 26.289 real overall: 4236783616 mem 1036.058 user 49.952 sys 666.063 real ls: cannot access '*.cram': No such file or directory