Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/69/b2ef13ddd77b0a8e407e2d4ffda592/.command.sh
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/fe/ece903b533b8d22cb85187a550da2b/1029_BICJ-T1-TDNA-1_A23MHWWLT4_1/1029_BICJ-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta.fai
  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/BWAIndex
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/69/b2ef13ddd77b0a8e407e2d4ffda592/.command.run
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/fe/ece903b533b8d22cb85187a550da2b/1029_BICJ-T1-TDNA-1_A23MHWWLT4_1/1029_BICJ-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz
==> STAGING COMPLETE (7 inputs)

This software is licensed to bgold@natera.com by Sentieon Inc.
cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1029_BICJ-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 1613.713 CPU sec, 55.708 real sec
[M::process] read 726142 sequences (100000063 bp) in 1.376 CPU sec, 1.380 real sec...
[M::process] read 725396 sequences (100000263 bp) in 2.070 CPU sec, 2.073 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (85, 286742, 65, 92)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 407, 821)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2083)
[M::mem_pestat] mean and std.dev: (564.35, 450.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2714)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 505)
[M::mem_pestat] mean and std.dev: (199.67, 91.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 630)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 441, 922)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2462)
[M::mem_pestat] mean and std.dev: (482.23, 475.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3232)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 522, 1388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3664)
[M::mem_pestat] mean and std.dev: (742.69, 623.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4802)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724442 sequences (100000030 bp) in 2.090 CPU sec, 2.093 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 287232, 77, 117)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 319, 718)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1770)
[M::mem_pestat] mean and std.dev: (413.56, 359.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2296)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 182, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 517)
[M::mem_pestat] mean and std.dev: (201.90, 93.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 646)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 477, 1278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3372)
[M::mem_pestat] mean and std.dev: (708.10, 743.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4419)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 531, 981)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2459)
[M::mem_pestat] mean and std.dev: (572.70, 485.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3198)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723974 sequences (100000039 bp) in 2.030 CPU sec, 2.030 real sec...
[M::mem_process_seqs] Processed 726142 reads in 221.492 CPU sec, 6.953 real sec
[M::mem_process_seqs] Processed 725396 reads in 160.467 CPU sec, 5.068 real sec
sorting block 0, #reads = 1076332 mem = 536881943 peak = 613658624
[M::process] read 724088 sequences (100000299 bp) in 2.161 CPU sec, 2.186 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (98, 287187, 58, 105)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 532, 1340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3532)
[M::mem_pestat] mean and std.dev: (785.34, 708.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4628)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 521)
[M::mem_pestat] mean and std.dev: (203.34, 94.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 651)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 388, 826)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2120)
[M::mem_pestat] mean and std.dev: (477.37, 481.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2767)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 320, 769)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1921)
[M::mem_pestat] mean and std.dev: (460.60, 404.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2497)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723158 sequences (100000038 bp) in 1.640 CPU sec, 1.641 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (94, 287103, 82, 95)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 383, 723)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1705)
[M::mem_pestat] mean and std.dev: (478.29, 334.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2196)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 524)
[M::mem_pestat] mean and std.dev: (204.50, 95.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 655)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (465, 1091, 2060)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5250)
[M::mem_pestat] mean and std.dev: (1173.31, 1010.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6845)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (269, 552, 1259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3239)
[M::mem_pestat] mean and std.dev: (724.08, 608.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4229)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724442 reads in 215.350 CPU sec, 6.848 real sec
sorting block 1, #reads = 1077114 mem = 536879923 peak = 774639616
[M::mem_process_seqs] Processed 723974 reads in 250.456 CPU sec, 7.979 real sec
[M::process] read 723242 sequences (100000144 bp) in 2.667 CPU sec, 2.685 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (92, 287165, 65, 115)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 604, 1877)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5135)
[M::mem_pestat] mean and std.dev: (963.56, 921.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6764)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 527)
[M::mem_pestat] mean and std.dev: (204.23, 95.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 659)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (60, 317, 973)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2799)
[M::mem_pestat] mean and std.dev: (566.05, 655.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3712)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 401, 788)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1910)
[M::mem_pestat] mean and std.dev: (482.94, 385.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2471)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725440 sequences (100000030 bp) in 2.160 CPU sec, 2.160 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (101, 286651, 64, 123)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 287, 605)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1433)
[M::mem_pestat] mean and std.dev: (361.17, 258.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1847)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 528)
[M::mem_pestat] mean and std.dev: (205.55, 96.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 660)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (325, 703, 1523)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3919)
[M::mem_pestat] mean and std.dev: (820.41, 764.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5117)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 418, 1172)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3076)
[M::mem_pestat] mean and std.dev: (659.56, 628.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4028)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724088 reads in 219.656 CPU sec, 6.954 real sec
sorting block 2, #reads = 1077876 mem = 536879139 peak = 875892736
[M::mem_process_seqs] Processed 723158 reads in 256.221 CPU sec, 8.136 real sec
sorting block 3, #reads = 1078011 mem = 536881138 peak = 875892736
[M::process] read 725350 sequences (100000204 bp) in 2.927 CPU sec, 2.955 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 286743, 82, 129)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 310, 844)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2154)
[M::mem_pestat] mean and std.dev: (510.00, 457.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2809)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 531)
[M::mem_pestat] mean and std.dev: (206.16, 97.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 664)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 454, 924)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2288)
[M::mem_pestat] mean and std.dev: (490.21, 450.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2970)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 467, 1072)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2766)
[M::mem_pestat] mean and std.dev: (702.05, 655.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3613)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724598 sequences (100000045 bp) in 2.275 CPU sec, 2.283 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 287350, 73, 105)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 507, 1220)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3276)
[M::mem_pestat] mean and std.dev: (736.96, 714.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4304)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 182, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 520)
[M::mem_pestat] mean and std.dev: (202.61, 95.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 650)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 795, 1531)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4203)
[M::mem_pestat] mean and std.dev: (780.36, 747.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5539)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (276, 476, 1604)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4260)
[M::mem_pestat] mean and std.dev: (884.03, 932.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5588)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723242 reads in 220.338 CPU sec, 6.967 real sec
[M::mem_process_seqs] Processed 725440 reads in 257.349 CPU sec, 8.171 real sec
sorting block 4, #reads = 1079414 mem = 536881274 peak = 875892736
[M::process] read 724208 sequences (100000028 bp) in 2.778 CPU sec, 2.801 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (95, 286965, 77, 86)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 629, 1091)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2911)
[M::mem_pestat] mean and std.dev: (586.05, 492.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3821)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 182, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 520)
[M::mem_pestat] mean and std.dev: (202.62, 94.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 650)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (249, 529, 1118)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2856)
[M::mem_pestat] mean and std.dev: (564.90, 520.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3725)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (272, 535, 845)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1991)
[M::mem_pestat] mean and std.dev: (569.83, 387.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2564)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723580 sequences (100000000 bp) in 2.219 CPU sec, 2.216 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (93, 286897, 63, 101)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 403, 1291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3457)
[M::mem_pestat] mean and std.dev: (647.58, 708.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4540)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 521)
[M::mem_pestat] mean and std.dev: (203.57, 94.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 651)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 546, 1389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3887)
[M::mem_pestat] mean and std.dev: (839.05, 813.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5136)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 548, 1331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3611)
[M::mem_pestat] mean and std.dev: (600.84, 622.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4751)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (79, 287055, 79, 104)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 494, 1092)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2776)
[M::mem_pestat] mean and std.dev: (719.89, 625.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3618)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 521)
[M::mem_pestat] mean and std.dev: (203.38, 95.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 651)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (275, 482, 1122)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2816)
[M::mem_pestat] mean and std.dev: (707.96, 617.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3663)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 441, 1109)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2889)
[M::mem_pestat] mean and std.dev: (588.55, 564.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3779)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 725350 reads in 311.267 CPU sec, 9.903 real sec
sorting block 5, #reads = 1077898 mem = 536878882 peak = 875892736
[M::mem_process_seqs] Processed 724208 reads in 251.149 CPU sec, 8.035 real sec
[M::mem_process_seqs] Processed 724598 reads in 289.621 CPU sec, 9.257 real sec
sorting block 6, #reads = 1076793 mem = 536877918 peak = 875892736
[M::process] read 723526 sequences (100000171 bp) in 3.343 CPU sec, 3.409 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (105, 286739, 80, 123)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (257, 537, 1290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3356)
[M::mem_pestat] mean and std.dev: (769.16, 753.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4389)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 525)
[M::mem_pestat] mean and std.dev: (204.61, 95.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 656)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 653, 1170)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3086)
[M::mem_pestat] mean and std.dev: (658.92, 494.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4044)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 471, 800)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1894)
[M::mem_pestat] mean and std.dev: (479.25, 327.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2441)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723724 sequences (100000109 bp) in 2.687 CPU sec, 2.704 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (107, 285840, 81, 112)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (257, 527, 1166)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2984)
[M::mem_pestat] mean and std.dev: (685.31, 573.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3893)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 522)
[M::mem_pestat] mean and std.dev: (203.91, 94.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 652)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 492, 1388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3814)
[M::mem_pestat] mean and std.dev: (497.34, 511.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5027)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 504, 1397)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3713)
[M::mem_pestat] mean and std.dev: (813.77, 792.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4871)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724252 sequences (100000010 bp) in 2.360 CPU sec, 2.356 real sec...
[M::mem_process_seqs] Processed 723580 reads in 227.695 CPU sec, 7.181 real sec
sorting block 7, #reads = 1078301 mem = 536876696 peak = 875892736
[M::mem_process_seqs] Processed 723526 reads in 164.274 CPU sec, 5.186 real sec
[M::process] read 722804 sequences (100000142 bp) in 2.970 CPU sec, 3.017 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (102, 286300, 71, 100)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 494, 981)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2571)
[M::mem_pestat] mean and std.dev: (584.43, 537.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3366)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 184, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 516)
[M::mem_pestat] mean and std.dev: (203.17, 93.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 644)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 701, 1074)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2820)
[M::mem_pestat] mean and std.dev: (616.48, 489.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3693)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (273, 544, 1592)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4230)
[M::mem_pestat] mean and std.dev: (763.68, 776.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5549)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722178 sequences (100000149 bp) in 1.850 CPU sec, 1.842 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (102, 285945, 74, 108)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 391, 1096)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2876)
[M::mem_pestat] mean and std.dev: (564.12, 526.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3766)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 518)
[M::mem_pestat] mean and std.dev: (202.71, 93.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 647)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 504, 1080)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2830)
[M::mem_pestat] mean and std.dev: (648.62, 566.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3705)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 506, 1111)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2821)
[M::mem_pestat] mean and std.dev: (587.52, 491.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3676)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723724 reads in 232.357 CPU sec, 7.375 real sec
sorting block 8, #reads = 1077238 mem = 536881082 peak = 879423488
[M::mem_process_seqs] Processed 724252 reads in 273.887 CPU sec, 8.727 real sec
sorting block 9, #reads = 1071997 mem = 536881416 peak = 929910784
[M::process] read 722528 sequences (100000065 bp) in 2.865 CPU sec, 2.895 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (105, 285983, 66, 97)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 342, 886)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2276)
[M::mem_pestat] mean and std.dev: (587.25, 543.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2971)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 522)
[M::mem_pestat] mean and std.dev: (203.94, 93.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 652)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 563, 1441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3987)
[M::mem_pestat] mean and std.dev: (827.30, 907.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5260)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 484, 920)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2380)
[M::mem_pestat] mean and std.dev: (597.42, 539.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3110)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721924 sequences (100000178 bp) in 2.431 CPU sec, 2.432 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (99, 285899, 71, 120)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 408, 1298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3506)
[M::mem_pestat] mean and std.dev: (624.51, 643.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4610)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 519)
[M::mem_pestat] mean and std.dev: (204.07, 93.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 648)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 485, 1087)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2749)
[M::mem_pestat] mean and std.dev: (675.83, 618.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3580)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 555, 1271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3425)
[M::mem_pestat] mean and std.dev: (735.80, 757.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4502)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 722804 reads in 224.438 CPU sec, 7.094 real sec
[M::process] read 721504 sequences (100000204 bp) in 2.677 CPU sec, 2.685 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (119, 285774, 48, 89)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 381, 899)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2297)
[M::mem_pestat] mean and std.dev: (565.23, 525.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2996)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 186, 264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 526)
[M::mem_pestat] mean and std.dev: (205.30, 94.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 657)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (131, 375, 990)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2708)
[M::mem_pestat] mean and std.dev: (466.91, 499.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3567)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 391, 816)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1980)
[M::mem_pestat] mean and std.dev: (532.17, 462.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2562)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 721924 reads in 138.894 CPU sec, 4.405 real sec
sorting block 10, #reads = 1076294 mem = 536880067 peak = 929910784
[M::mem_process_seqs] Processed 722178 reads in 435.817 CPU sec, 13.842 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (103, 286010, 79, 87)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (263, 543, 1091)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2747)
[M::mem_pestat] mean and std.dev: (680.22, 531.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3575)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 186, 262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 522)
[M::mem_pestat] mean and std.dev: (204.59, 94.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 652)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 357, 1338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3726)
[M::mem_pestat] mean and std.dev: (650.50, 804.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4920)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 380, 1392)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3784)
[M::mem_pestat] mean and std.dev: (723.82, 746.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4980)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 11, #reads = 1075123 mem = 536882091 peak = 1007742976
[M::process] read 721000 sequences (100000177 bp) in 2.973 CPU sec, 3.215 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (140, 285686, 79, 106)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 297, 783)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1975)
[M::mem_pestat] mean and std.dev: (500.76, 459.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2571)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 187, 264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 526)
[M::mem_pestat] mean and std.dev: (205.66, 94.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 657)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 765, 1478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3932)
[M::mem_pestat] mean and std.dev: (838.14, 652.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5159)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 525, 1112)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2900)
[M::mem_pestat] mean and std.dev: (743.00, 715.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3794)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722952 sequences (100000087 bp) in 2.460 CPU sec, 2.456 real sec...
[M::mem_process_seqs] Processed 722528 reads in 354.415 CPU sec, 11.205 real sec
[M::mem_process_seqs] Processed 721504 reads in 165.639 CPU sec, 5.233 real sec
sorting block 12, #reads = 1075200 mem = 536880843 peak = 1007742976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (103, 285529, 47, 94)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 316, 807)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1989)
[M::mem_pestat] mean and std.dev: (517.44, 467.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2580)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 187, 265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 527)
[M::mem_pestat] mean and std.dev: (206.13, 94.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 658)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 404, 1573)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4391)
[M::mem_pestat] mean and std.dev: (803.42, 850.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5800)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 336, 824)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2084)
[M::mem_pestat] mean and std.dev: (433.58, 350.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2714)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724876 sequences (100000081 bp) in 3.134 CPU sec, 3.198 real sec...
[M::process] read 724666 sequences (100000208 bp) in 2.450 CPU sec, 2.442 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (119, 286006, 54, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 348, 902)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2268)
[M::mem_pestat] mean and std.dev: (517.54, 443.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2951)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 522)
[M::mem_pestat] mean and std.dev: (204.38, 94.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 652)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (118, 565, 1239)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3481)
[M::mem_pestat] mean and std.dev: (744.16, 825.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4602)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (267, 702, 1252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3222)
[M::mem_pestat] mean and std.dev: (818.39, 698.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4207)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 721000 reads in 225.302 CPU sec, 7.133 real sec
sorting block 13, #reads = 1074661 mem = 536876478 peak = 1007742976
[M::mem_process_seqs] Processed 722952 reads in 174.380 CPU sec, 5.549 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (117, 287433, 60, 86)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 331, 829)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2057)
[M::mem_pestat] mean and std.dev: (488.26, 400.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2671)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 521)
[M::mem_pestat] mean and std.dev: (203.22, 95.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 651)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 536, 1381)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3867)
[M::mem_pestat] mean and std.dev: (608.46, 722.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5110)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 388, 1327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3535)
[M::mem_pestat] mean and std.dev: (619.74, 593.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4639)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724206 sequences (100000254 bp) in 3.404 CPU sec, 3.442 real sec...
[M::process] read 724120 sequences (100000151 bp) in 2.450 CPU sec, 2.453 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (92, 286655, 78, 90)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 363, 690)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1688)
[M::mem_pestat] mean and std.dev: (406.43, 335.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2187)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 183, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 514)
[M::mem_pestat] mean and std.dev: (201.97, 93.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 642)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (323, 631, 1422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3620)
[M::mem_pestat] mean and std.dev: (771.15, 713.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4719)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (286, 415, 943)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2257)
[M::mem_pestat] mean and std.dev: (541.57, 414.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2914)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724666 reads in 222.625 CPU sec, 7.031 real sec
sorting block 14, #reads = 1075627 mem = 536880141 peak = 1007742976
[M::mem_process_seqs] Processed 724876 reads in 259.135 CPU sec, 8.217 real sec
sorting block 15, #reads = 1078948 mem = 536880007 peak = 1023258624
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (128, 287110, 61, 98)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 392, 1011)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2565)
[M::mem_pestat] mean and std.dev: (628.95, 530.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3342)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 524)
[M::mem_pestat] mean and std.dev: (204.20, 95.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 655)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 553, 1370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3744)
[M::mem_pestat] mean and std.dev: (764.64, 807.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4931)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (276, 493, 1136)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2856)
[M::mem_pestat] mean and std.dev: (709.21, 682.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3716)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723480 sequences (100000145 bp) in 3.421 CPU sec, 3.480 real sec...
[M::process] read 723048 sequences (100000277 bp) in 1.940 CPU sec, 1.941 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (91, 286712, 65, 98)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 501, 1014)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2670)
[M::mem_pestat] mean and std.dev: (644.76, 574.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3498)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 521)
[M::mem_pestat] mean and std.dev: (203.39, 95.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 651)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 705, 1058)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2678)
[M::mem_pestat] mean and std.dev: (549.42, 421.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3488)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (297, 506, 1239)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3123)
[M::mem_pestat] mean and std.dev: (692.90, 671.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4065)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724120 reads in 224.775 CPU sec, 7.126 real sec
[M::mem_process_seqs] Processed 724206 reads in 266.815 CPU sec, 8.484 real sec
sorting block 16, #reads = 1077861 mem = 536879171 peak = 1023258624
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (103, 287240, 65, 122)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 517, 1270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3416)
[M::mem_pestat] mean and std.dev: (703.09, 695.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4489)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 528)
[M::mem_pestat] mean and std.dev: (205.62, 96.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 660)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 765, 1341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3595)
[M::mem_pestat] mean and std.dev: (834.15, 835.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4722)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 466, 933)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2319)
[M::mem_pestat] mean and std.dev: (598.84, 497.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3012)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723614 sequences (100000248 bp) in 3.529 CPU sec, 3.574 real sec...
[M::process] read 725036 sequences (100000190 bp) in 2.070 CPU sec, 2.072 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (104, 286880, 84, 117)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 297, 883)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2285)
[M::mem_pestat] mean and std.dev: (529.74, 485.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2986)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 531)
[M::mem_pestat] mean and std.dev: (206.33, 97.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 664)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 635, 1283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3369)
[M::mem_pestat] mean and std.dev: (749.56, 666.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4412)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 353, 951)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2407)
[M::mem_pestat] mean and std.dev: (508.42, 478.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3135)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723480 reads in 220.613 CPU sec, 6.974 real sec
sorting block 17, #reads = 1078261 mem = 536878983 peak = 1023258624
[M::mem_process_seqs] Processed 723048 reads in 256.514 CPU sec, 8.140 real sec
sorting block 18, #reads = 1079349 mem = 536886036 peak = 1023258624
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (102, 286689, 58, 104)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 432, 1007)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2541)
[M::mem_pestat] mean and std.dev: (594.14, 494.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3308)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 531)
[M::mem_pestat] mean and std.dev: (206.11, 97.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 664)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 669, 1135)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2877)
[M::mem_pestat] mean and std.dev: (637.22, 559.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3748)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 435, 750)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1796)
[M::mem_pestat] mean and std.dev: (439.76, 351.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2319)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724100 sequences (100000047 bp) in 3.576 CPU sec, 3.627 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (88, 287680, 88, 100)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 492, 1215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3167)
[M::mem_pestat] mean and std.dev: (730.19, 661.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4143)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 518)
[M::mem_pestat] mean and std.dev: (202.64, 94.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 647)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (565, 1154, 3365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8965)
[M::mem_pestat] mean and std.dev: (1946.34, 2008.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11765)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (267, 633, 1297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3357)
[M::mem_pestat] mean and std.dev: (666.40, 611.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4387)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723810 sequences (100000259 bp) in 2.460 CPU sec, 2.462 real sec...
[M::mem_process_seqs] Processed 723614 reads in 219.884 CPU sec, 6.941 real sec
[M::mem_process_seqs] Processed 725036 reads in 255.264 CPU sec, 8.087 real sec
sorting block 19, #reads = 1078395 mem = 536883456 peak = 1023258624
[M::process] read 723996 sequences (100000206 bp) in 3.082 CPU sec, 3.117 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (106, 287052, 83, 91)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 404, 989)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2465)
[M::mem_pestat] mean and std.dev: (567.30, 488.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3203)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 524)
[M::mem_pestat] mean and std.dev: (204.20, 95.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 655)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (279, 514, 1353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3501)
[M::mem_pestat] mean and std.dev: (700.01, 672.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4575)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 347, 1071)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2811)
[M::mem_pestat] mean and std.dev: (510.06, 453.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3681)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723750 sequences (100000259 bp) in 2.000 CPU sec, 2.008 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (88, 286725, 66, 90)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 519, 939)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2459)
[M::mem_pestat] mean and std.dev: (669.63, 594.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3219)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 521)
[M::mem_pestat] mean and std.dev: (203.76, 94.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 651)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 680, 987)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2565)
[M::mem_pestat] mean and std.dev: (640.67, 533.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3354)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 420, 1034)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2700)
[M::mem_pestat] mean and std.dev: (566.51, 484.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3533)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724100 reads in 221.733 CPU sec, 7.036 real sec
sorting block 20, #reads = 1079582 mem = 536877070 peak = 1023258624
[M::mem_process_seqs] Processed 723810 reads in 261.603 CPU sec, 8.327 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (83, 286310, 65, 112)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 382, 1287)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3443)
[M::mem_pestat] mean and std.dev: (708.15, 708.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4521)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 184, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 519)
[M::mem_pestat] mean and std.dev: (203.76, 94.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 648)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (109, 419, 1028)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2866)
[M::mem_pestat] mean and std.dev: (599.41, 606.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3785)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 455, 1279)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3379)
[M::mem_pestat] mean and std.dev: (718.97, 729.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4429)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723700 sequences (100000167 bp) in 3.354 CPU sec, 3.410 real sec...
[M::process] read 726108 sequences (100000300 bp) in 2.530 CPU sec, 2.529 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (93, 286409, 59, 93)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 374, 1067)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2821)
[M::mem_pestat] mean and std.dev: (587.32, 560.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3698)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 521)
[M::mem_pestat] mean and std.dev: (203.28, 94.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 651)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (283, 672, 1328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3418)
[M::mem_pestat] mean and std.dev: (828.85, 804.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4463)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 402, 1401)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3723)
[M::mem_pestat] mean and std.dev: (761.02, 723.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4884)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723996 reads in 222.531 CPU sec, 7.020 real sec
sorting block 21, #reads = 1078511 mem = 536882505 peak = 1023258624
[M::mem_process_seqs] Processed 723750 reads in 258.481 CPU sec, 8.188 real sec
sorting block 22, #reads = 1076223 mem = 536876543 peak = 1023258624
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (84, 286148, 70, 88)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 496, 1078)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2814)
[M::mem_pestat] mean and std.dev: (699.16, 641.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3682)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 515)
[M::mem_pestat] mean and std.dev: (202.33, 93.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 643)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 585, 1179)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3049)
[M::mem_pestat] mean and std.dev: (644.38, 591.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3984)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 393, 1061)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2719)
[M::mem_pestat] mean and std.dev: (600.84, 580.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3548)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723746 sequences (100000292 bp) in 3.551 CPU sec, 3.583 real sec...
[M::process] read 722914 sequences (100000176 bp) in 2.500 CPU sec, 2.500 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 287239, 62, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 440, 1241)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3265)
[M::mem_pestat] mean and std.dev: (648.16, 591.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4277)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 508)
[M::mem_pestat] mean and std.dev: (200.25, 92.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 634)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (98, 376, 588)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1568)
[M::mem_pestat] mean and std.dev: (345.09, 286.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2058)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 568, 1919)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5243)
[M::mem_pestat] mean and std.dev: (1138.60, 1268.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6905)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723700 reads in 233.891 CPU sec, 7.389 real sec
[M::process] read 723050 sequences (100000005 bp) in 2.956 CPU sec, 2.964 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (107, 286572, 71, 89)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (257, 363, 814)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1928)
[M::mem_pestat] mean and std.dev: (459.41, 346.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2485)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 518)
[M::mem_pestat] mean and std.dev: (202.92, 93.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 647)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (100, 523, 1507)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4321)
[M::mem_pestat] mean and std.dev: (823.05, 1045.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5728)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 357, 1146)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3026)
[M::mem_pestat] mean and std.dev: (703.95, 738.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3966)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723746 reads in 125.564 CPU sec, 3.976 real sec
sorting block 23, #reads = 1077143 mem = 536879784 peak = 1023258624
[M::mem_process_seqs] Processed 726108 reads in 335.996 CPU sec, 10.677 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (84, 286789, 67, 97)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 578, 1261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3311)
[M::mem_pestat] mean and std.dev: (706.24, 622.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4336)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 519)
[M::mem_pestat] mean and std.dev: (203.91, 94.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 648)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 697, 1899)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5267)
[M::mem_pestat] mean and std.dev: (1094.56, 1204.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6951)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 328, 819)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2013)
[M::mem_pestat] mean and std.dev: (451.55, 394.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2610)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 24, #reads = 1074656 mem = 536880013 peak = 1023258624
[M::process] read 722012 sequences (100000091 bp) in 3.606 CPU sec, 3.671 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (96, 286362, 67, 109)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 328, 864)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2204)
[M::mem_pestat] mean and std.dev: (498.44, 462.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2874)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 519)
[M::mem_pestat] mean and std.dev: (203.53, 93.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 648)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 524, 1509)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4165)
[M::mem_pestat] mean and std.dev: (855.59, 917.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5493)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 380, 930)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2388)
[M::mem_pestat] mean and std.dev: (567.66, 510.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3117)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 722914 reads in 349.588 CPU sec, 11.051 real sec
[M::process] read 722258 sequences (100000023 bp) in 2.432 CPU sec, 2.443 real sec...
[M::process] read 721896 sequences (100000015 bp) in 2.704 CPU sec, 2.710 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (107, 285731, 79, 108)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (297, 514, 923)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2175)
[M::mem_pestat] mean and std.dev: (576.18, 429.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2801)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 187, 262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 520)
[M::mem_pestat] mean and std.dev: (205.05, 94.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 649)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (128, 298, 968)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2648)
[M::mem_pestat] mean and std.dev: (335.46, 295.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3488)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 393, 1031)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2635)
[M::mem_pestat] mean and std.dev: (634.59, 582.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3437)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 722012 reads in 127.349 CPU sec, 4.029 real sec
sorting block 25, #reads = 1076891 mem = 536880757 peak = 1023258624
[M::mem_process_seqs] Processed 723050 reads in 328.191 CPU sec, 10.386 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (89, 285959, 61, 112)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 301, 826)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2148)
[M::mem_pestat] mean and std.dev: (474.12, 445.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2809)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 186, 264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 526)
[M::mem_pestat] mean and std.dev: (205.40, 94.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 657)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 513, 1054)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2880)
[M::mem_pestat] mean and std.dev: (491.59, 416.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3793)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 395, 965)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2441)
[M::mem_pestat] mean and std.dev: (560.30, 523.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3179)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 26, #reads = 1076816 mem = 536882503 peak = 1029763072
[M::process] read 721770 sequences (100000260 bp) in 3.591 CPU sec, 3.653 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (110, 285789, 68, 101)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 404, 1216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3176)
[M::mem_pestat] mean and std.dev: (634.66, 668.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4156)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 187, 265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 529)
[M::mem_pestat] mean and std.dev: (206.08, 95.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 661)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 659, 1268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3362)
[M::mem_pestat] mean and std.dev: (796.29, 725.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4409)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (260, 520, 1144)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2912)
[M::mem_pestat] mean and std.dev: (683.12, 575.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3796)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725952 sequences (100000172 bp) in 2.260 CPU sec, 2.258 real sec...
[M::mem_process_seqs] Processed 722258 reads in 354.784 CPU sec, 11.227 real sec
[M::mem_process_seqs] Processed 721896 reads in 169.090 CPU sec, 5.355 real sec
sorting block 27, #reads = 1075475 mem = 536885023 peak = 1029763072
[M::process] read 724808 sequences (100000227 bp) in 2.951 CPU sec, 3.015 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (97, 286044, 48, 90)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 451, 915)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2325)
[M::mem_pestat] mean and std.dev: (544.42, 475.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3030)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 187, 264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 526)
[M::mem_pestat] mean and std.dev: (205.75, 95.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 657)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (283, 666, 983)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2383)
[M::mem_pestat] mean and std.dev: (671.36, 540.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3083)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 413, 825)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1987)
[M::mem_pestat] mean and std.dev: (497.15, 352.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2568)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 721770 reads in 134.494 CPU sec, 4.308 real sec
sorting block 28, #reads = 1076316 mem = 536885384 peak = 1029763072
[M::process] read 723270 sequences (100000218 bp) in 2.862 CPU sec, 2.898 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (91, 287081, 56, 114)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 335, 1014)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2642)
[M::mem_pestat] mean and std.dev: (569.65, 587.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3456)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 511)
[M::mem_pestat] mean and std.dev: (200.74, 92.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 638)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 637, 1084)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2774)
[M::mem_pestat] mean and std.dev: (671.31, 589.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3619)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 405, 896)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2268)
[M::mem_pestat] mean and std.dev: (556.48, 507.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2954)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723190 sequences (100000033 bp) in 2.598 CPU sec, 2.608 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 286465, 66, 98)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 419, 833)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2165)
[M::mem_pestat] mean and std.dev: (513.92, 407.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2831)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 184, 263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 525)
[M::mem_pestat] mean and std.dev: (204.62, 95.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 656)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 523, 1063)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2779)
[M::mem_pestat] mean and std.dev: (585.02, 511.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3637)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 378, 1003)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2633)
[M::mem_pestat] mean and std.dev: (588.01, 534.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3448)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (109, 287143, 61, 98)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 343, 789)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1945)
[M::mem_pestat] mean and std.dev: (447.23, 367.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2523)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 518)
[M::mem_pestat] mean and std.dev: (202.54, 94.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 647)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 757, 1449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3881)
[M::mem_pestat] mean and std.dev: (839.43, 741.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5097)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (301, 489, 1514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3940)
[M::mem_pestat] mean and std.dev: (790.04, 692.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5153)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 725952 reads in 353.312 CPU sec, 11.316 real sec
[M::mem_process_seqs] Processed 723270 reads in 253.088 CPU sec, 8.127 real sec
sorting block 29, #reads = 1076703 mem = 536880500 peak = 1029763072
[M::process] read 722726 sequences (100000090 bp) in 3.360 CPU sec, 3.426 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (97, 286748, 89, 95)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 484, 1440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3914)
[M::mem_pestat] mean and std.dev: (728.02, 844.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5151)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 186, 265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 531)
[M::mem_pestat] mean and std.dev: (205.99, 96.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 664)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 992, 2295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6485)
[M::mem_pestat] mean and std.dev: (1355.41, 1499.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8580)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 306, 677)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1627)
[M::mem_pestat] mean and std.dev: (420.61, 335.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2102)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723190 reads in 133.248 CPU sec, 4.190 real sec
[M::process] read 721980 sequences (100000164 bp) in 2.300 CPU sec, 2.293 real sec...
sorting block 30, #reads = 1077279 mem = 536884367 peak = 1029763072
[M::mem_process_seqs] Processed 724808 reads in 462.157 CPU sec, 14.747 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (115, 286874, 83, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 441, 1422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3808)
[M::mem_pestat] mean and std.dev: (762.00, 748.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5001)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 186, 267)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 537)
[M::mem_pestat] mean and std.dev: (207.34, 98.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 672)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 486, 956)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2576)
[M::mem_pestat] mean and std.dev: (512.17, 508.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3386)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (322, 611, 981)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2299)
[M::mem_pestat] mean and std.dev: (636.28, 422.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2958)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722618 sequences (100000296 bp) in 3.212 CPU sec, 3.397 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (94, 286634, 92, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 524, 1314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3472)
[M::mem_pestat] mean and std.dev: (650.75, 600.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4551)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 187, 268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 538)
[M::mem_pestat] mean and std.dev: (208.53, 98.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 673)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (89, 200, 742)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2048)
[M::mem_pestat] mean and std.dev: (359.89, 406.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2701)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 601, 1349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3573)
[M::mem_pestat] mean and std.dev: (867.52, 871.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4685)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724620 sequences (100000061 bp) in 2.280 CPU sec, 2.281 real sec...
[M::mem_process_seqs] Processed 722726 reads in 262.592 CPU sec, 8.284 real sec
sorting block 31, #reads = 1077977 mem = 536885953 peak = 1029763072
[M::mem_process_seqs] Processed 721980 reads in 165.469 CPU sec, 5.233 real sec
sorting block 32, #reads = 1077642 mem = 536879598 peak = 1074700288
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (112, 286617, 58, 97)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 556, 1046)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2720)
[M::mem_pestat] mean and std.dev: (692.23, 637.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3557)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 187, 267)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 537)
[M::mem_pestat] mean and std.dev: (207.90, 98.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 672)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 609, 1055)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2829)
[M::mem_pestat] mean and std.dev: (605.91, 467.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3716)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 437, 1527)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4179)
[M::mem_pestat] mean and std.dev: (769.40, 841.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5505)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724490 sequences (100000051 bp) in 3.325 CPU sec, 3.363 real sec...
[M::process] read 723090 sequences (100000059 bp) in 1.968 CPU sec, 1.972 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (96, 286993, 100, 103)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 383, 860)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2188)
[M::mem_pestat] mean and std.dev: (530.44, 420.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2852)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 521)
[M::mem_pestat] mean and std.dev: (203.45, 95.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 651)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 652, 1340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3688)
[M::mem_pestat] mean and std.dev: (747.47, 772.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4862)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 524, 985)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2465)
[M::mem_pestat] mean and std.dev: (635.02, 529.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3205)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 722618 reads in 224.870 CPU sec, 7.125 real sec
[M::mem_process_seqs] Processed 724620 reads in 163.155 CPU sec, 5.198 real sec
sorting block 33, #reads = 1077682 mem = 536881234 peak = 1074700288
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (92, 287360, 62, 88)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (280, 428, 945)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2275)
[M::mem_pestat] mean and std.dev: (593.13, 492.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2940)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 521)
[M::mem_pestat] mean and std.dev: (203.27, 94.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 651)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (275, 659, 1002)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2456)
[M::mem_pestat] mean and std.dev: (593.21, 374.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3183)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 343, 921)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2251)
[M::mem_pestat] mean and std.dev: (571.94, 508.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2916)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723112 sequences (100000070 bp) in 3.342 CPU sec, 3.387 real sec...
[M::process] read 723348 sequences (100000138 bp) in 2.490 CPU sec, 2.495 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (119, 286727, 73, 97)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 346, 1030)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2680)
[M::mem_pestat] mean and std.dev: (590.36, 572.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3505)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 525)
[M::mem_pestat] mean and std.dev: (204.97, 95.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 656)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (501, 1009, 2113)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5337)
[M::mem_pestat] mean and std.dev: (1058.15, 838.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6949)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 390, 824)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1980)
[M::mem_pestat] mean and std.dev: (443.69, 347.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2558)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724490 reads in 224.463 CPU sec, 7.096 real sec
sorting block 34, #reads = 1078363 mem = 536879123 peak = 1074700288
[M::process] read 723072 sequences (100000136 bp) in 2.866 CPU sec, 2.871 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (102, 286377, 74, 92)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 516, 1372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3620)
[M::mem_pestat] mean and std.dev: (747.45, 777.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4744)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 184, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 516)
[M::mem_pestat] mean and std.dev: (203.20, 93.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 644)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (281, 792, 1528)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4022)
[M::mem_pestat] mean and std.dev: (830.89, 718.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5269)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 562, 1043)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2679)
[M::mem_pestat] mean and std.dev: (605.48, 501.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3497)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723348 reads in 142.013 CPU sec, 4.500 real sec
sorting block 35, #reads = 1077752 mem = 536879978 peak = 1074700288
[M::mem_process_seqs] Processed 723090 reads in 345.284 CPU sec, 10.966 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (108, 285953, 73, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 368, 848)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2126)
[M::mem_pestat] mean and std.dev: (500.84, 450.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2765)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 522)
[M::mem_pestat] mean and std.dev: (204.17, 94.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 652)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (253, 533, 1107)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2815)
[M::mem_pestat] mean and std.dev: (681.77, 602.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3669)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 383, 885)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2227)
[M::mem_pestat] mean and std.dev: (500.84, 411.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2898)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723978 sequences (100000191 bp) in 3.219 CPU sec, 3.490 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (144, 285486, 70, 114)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 345, 832)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2010)
[M::mem_pestat] mean and std.dev: (534.01, 453.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2599)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 184, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 519)
[M::mem_pestat] mean and std.dev: (203.31, 93.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 648)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (284, 845, 1288)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3296)
[M::mem_pestat] mean and std.dev: (803.56, 671.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4300)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (332, 739, 1381)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3479)
[M::mem_pestat] mean and std.dev: (892.28, 730.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4528)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723272 sequences (100000044 bp) in 2.615 CPU sec, 2.619 real sec...
[M::mem_process_seqs] Processed 723112 reads in 378.902 CPU sec, 12.004 real sec
sorting block 36, #reads = 1076115 mem = 536889879 peak = 1074700288
[M::mem_process_seqs] Processed 723072 reads in 189.647 CPU sec, 6.022 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (91, 286352, 83, 108)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 400, 804)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1936)
[M::mem_pestat] mean and std.dev: (461.88, 381.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2502)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 518)
[M::mem_pestat] mean and std.dev: (202.75, 93.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 647)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 524, 1039)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2703)
[M::mem_pestat] mean and std.dev: (573.51, 489.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3535)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (262, 568, 976)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2404)
[M::mem_pestat] mean and std.dev: (672.24, 525.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3118)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 37, #reads = 1075990 mem = 536878585 peak = 1074700288
[M::process] read 722998 sequences (100000146 bp) in 3.989 CPU sec, 4.096 real sec...
[M::process] read 723314 sequences (100000279 bp) in 2.598 CPU sec, 2.599 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (96, 286267, 66, 102)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 510, 1566)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4290)
[M::mem_pestat] mean and std.dev: (718.52, 768.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5652)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 184, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 516)
[M::mem_pestat] mean and std.dev: (202.69, 93.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 644)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 545, 938)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2486)
[M::mem_pestat] mean and std.dev: (573.10, 586.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3260)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (265, 452, 1061)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2653)
[M::mem_pestat] mean and std.dev: (638.15, 539.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3449)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723978 reads in 258.649 CPU sec, 8.221 real sec
[M::mem_process_seqs] Processed 723272 reads in 190.199 CPU sec, 6.066 real sec
sorting block 38, #reads = 1076156 mem = 536879619 peak = 1074700288
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 286428, 72, 111)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 476, 1005)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2575)
[M::mem_pestat] mean and std.dev: (648.96, 549.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3360)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 516)
[M::mem_pestat] mean and std.dev: (203.19, 93.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 644)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 565, 1202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3134)
[M::mem_pestat] mean and std.dev: (708.44, 609.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4100)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 367, 1118)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2966)
[M::mem_pestat] mean and std.dev: (647.55, 688.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3890)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722762 sequences (100000188 bp) in 3.236 CPU sec, 3.289 real sec...
[M::process] read 722296 sequences (100000163 bp) in 2.580 CPU sec, 2.583 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (99, 286440, 88, 113)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 401, 1136)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2952)
[M::mem_pestat] mean and std.dev: (609.89, 558.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3860)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 184, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 519)
[M::mem_pestat] mean and std.dev: (203.81, 94.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 648)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 579, 1388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3864)
[M::mem_pestat] mean and std.dev: (811.43, 875.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5102)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (288, 551, 1139)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2841)
[M::mem_pestat] mean and std.dev: (703.21, 581.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3692)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 722998 reads in 243.903 CPU sec, 7.734 real sec
sorting block 39, #reads = 1075800 mem = 536880266 peak = 1074700288
[M::mem_process_seqs] Processed 723314 reads in 177.684 CPU sec, 5.643 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (81, 286286, 64, 95)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 338, 1054)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2766)
[M::mem_pestat] mean and std.dev: (502.14, 486.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3622)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 522)
[M::mem_pestat] mean and std.dev: (204.16, 94.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 652)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 576, 1736)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4856)
[M::mem_pestat] mean and std.dev: (878.79, 935.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6416)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 447, 776)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1898)
[M::mem_pestat] mean and std.dev: (487.66, 382.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2459)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722810 sequences (100000051 bp) in 3.666 CPU sec, 3.715 real sec...
[M::process] read 722396 sequences (100000286 bp) in 2.310 CPU sec, 2.309 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (86, 285827, 64, 122)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 344, 1058)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2880)
[M::mem_pestat] mean and std.dev: (618.61, 628.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3791)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 186, 262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 520)
[M::mem_pestat] mean and std.dev: (204.64, 94.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 649)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 560, 1195)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3173)
[M::mem_pestat] mean and std.dev: (657.48, 579.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4162)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 377, 1189)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3055)
[M::mem_pestat] mean and std.dev: (670.94, 686.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3988)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 722762 reads in 242.622 CPU sec, 7.689 real sec
sorting block 40, #reads = 1076691 mem = 536879677 peak = 1074700288
[M::mem_process_seqs] Processed 722296 reads in 179.086 CPU sec, 5.703 real sec
sorting block 41, #reads = 1074965 mem = 536881052 peak = 1074700288
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (114, 286511, 67, 94)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 362, 610)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1436)
[M::mem_pestat] mean and std.dev: (364.82, 245.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1849)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 186, 262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 522)
[M::mem_pestat] mean and std.dev: (204.62, 94.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 652)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (337, 546, 1154)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2788)
[M::mem_pestat] mean and std.dev: (753.32, 641.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3605)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (265, 522, 946)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2308)
[M::mem_pestat] mean and std.dev: (606.83, 433.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2989)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723044 sequences (100000238 bp) in 3.023 CPU sec, 3.078 real sec...
[M::process] read 724330 sequences (100000030 bp) in 2.250 CPU sec, 2.254 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (100, 286111, 100, 98)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 489, 1124)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3008)
[M::mem_pestat] mean and std.dev: (667.03, 632.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3950)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 186, 263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 525)
[M::mem_pestat] mean and std.dev: (204.87, 94.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 656)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 454, 1098)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2942)
[M::mem_pestat] mean and std.dev: (587.20, 598.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3864)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 411, 932)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2318)
[M::mem_pestat] mean and std.dev: (537.95, 456.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3011)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 722810 reads in 242.053 CPU sec, 7.684 real sec
[M::mem_process_seqs] Processed 722396 reads in 178.703 CPU sec, 5.693 real sec
sorting block 42, #reads = 1078314 mem = 536882903 peak = 1074700288
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (113, 286676, 60, 112)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 353, 970)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2512)
[M::mem_pestat] mean and std.dev: (601.12, 569.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3283)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 518)
[M::mem_pestat] mean and std.dev: (202.76, 94.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 647)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 314, 890)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2378)
[M::mem_pestat] mean and std.dev: (507.59, 563.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3122)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 362, 760)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1800)
[M::mem_pestat] mean and std.dev: (483.97, 374.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2320)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723802 sequences (100000192 bp) in 3.529 CPU sec, 3.576 real sec...
[M::process] read 723110 sequences (100000275 bp) in 2.510 CPU sec, 2.507 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (118, 286579, 69, 118)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 471, 964)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2462)
[M::mem_pestat] mean and std.dev: (553.88, 463.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3211)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 522)
[M::mem_pestat] mean and std.dev: (204.01, 94.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 652)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (278, 554, 1561)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4127)
[M::mem_pestat] mean and std.dev: (743.22, 723.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5410)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 529, 1122)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2852)
[M::mem_pestat] mean and std.dev: (658.42, 568.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3717)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724330 reads in 242.225 CPU sec, 7.670 real sec
sorting block 43, #reads = 1078452 mem = 536877817 peak = 1074700288
[M::mem_process_seqs] Processed 723044 reads in 283.291 CPU sec, 9.000 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (109, 286530, 61, 130)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 341, 715)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1783)
[M::mem_pestat] mean and std.dev: (363.92, 269.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2317)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 525)
[M::mem_pestat] mean and std.dev: (204.97, 95.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 656)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 713, 2045)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5681)
[M::mem_pestat] mean and std.dev: (964.42, 925.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7499)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 390, 806)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2012)
[M::mem_pestat] mean and std.dev: (533.21, 459.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2615)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722774 sequences (100000053 bp) in 3.735 CPU sec, 3.814 real sec...
[M::process] read 722318 sequences (100000100 bp) in 2.490 CPU sec, 2.493 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (99, 286642, 53, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 579, 1421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3803)
[M::mem_pestat] mean and std.dev: (777.84, 749.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4994)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 524)
[M::mem_pestat] mean and std.dev: (204.36, 95.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 655)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (436, 890, 1665)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4123)
[M::mem_pestat] mean and std.dev: (929.94, 753.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5352)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 420, 1205)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3153)
[M::mem_pestat] mean and std.dev: (657.44, 691.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4127)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723110 reads in 234.057 CPU sec, 7.408 real sec
sorting block 44, #reads = 1076938 mem = 536891702 peak = 1074700288
[M::mem_process_seqs] Processed 723802 reads in 277.255 CPU sec, 8.803 real sec
sorting block 45, #reads = 1078308 mem = 536886526 peak = 1105027072
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (87, 286527, 75, 107)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 311, 875)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2253)
[M::mem_pestat] mean and std.dev: (460.26, 412.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2942)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 186, 266)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 534)
[M::mem_pestat] mean and std.dev: (207.02, 97.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 668)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 617, 1533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4211)
[M::mem_pestat] mean and std.dev: (761.27, 761.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5550)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 452, 978)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2462)
[M::mem_pestat] mean and std.dev: (615.67, 514.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3204)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721552 sequences (100000108 bp) in 3.435 CPU sec, 3.493 real sec...
[M::process] read 722196 sequences (100000080 bp) in 2.188 CPU sec, 2.193 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (88, 285879, 64, 123)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (392, 791, 1249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2963)
[M::mem_pestat] mean and std.dev: (794.68, 574.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3820)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 528)
[M::mem_pestat] mean and std.dev: (205.73, 96.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 660)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (96, 443, 1283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3657)
[M::mem_pestat] mean and std.dev: (604.63, 583.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4844)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (275, 390, 893)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2129)
[M::mem_pestat] mean and std.dev: (539.09, 406.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2747)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 722318 reads in 238.617 CPU sec, 7.562 real sec
[M::mem_process_seqs] Processed 722774 reads in 278.646 CPU sec, 8.865 real sec
sorting block 46, #reads = 1079359 mem = 536878782 peak = 1105027072
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (102, 285904, 70, 106)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 475, 1216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3234)
[M::mem_pestat] mean and std.dev: (707.51, 621.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4243)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 187, 268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 538)
[M::mem_pestat] mean and std.dev: (208.05, 98.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 673)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 595, 1442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4058)
[M::mem_pestat] mean and std.dev: (899.44, 913.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5366)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 503, 960)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2438)
[M::mem_pestat] mean and std.dev: (599.88, 517.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3177)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724040 sequences (100000051 bp) in 3.193 CPU sec, 3.249 real sec...
[M::process] read 723308 sequences (100000076 bp) in 2.520 CPU sec, 2.515 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 286532, 82, 125)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 411, 1304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3546)
[M::mem_pestat] mean and std.dev: (633.01, 655.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4667)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 186, 265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 529)
[M::mem_pestat] mean and std.dev: (206.55, 96.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 661)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (82, 313, 675)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1861)
[M::mem_pestat] mean and std.dev: (365.05, 339.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2454)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 477, 1016)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2600)
[M::mem_pestat] mean and std.dev: (627.28, 591.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3392)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 721552 reads in 232.864 CPU sec, 7.369 real sec
sorting block 47, #reads = 1077213 mem = 536886592 peak = 1105027072
[M::mem_process_seqs] Processed 722196 reads in 171.350 CPU sec, 5.447 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (115, 286513, 76, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (306, 649, 1378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3522)
[M::mem_pestat] mean and std.dev: (754.73, 626.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4594)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 518)
[M::mem_pestat] mean and std.dev: (202.67, 94.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 647)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (293, 483, 1004)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2426)
[M::mem_pestat] mean and std.dev: (562.70, 426.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3137)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 351, 876)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2160)
[M::mem_pestat] mean and std.dev: (503.00, 419.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2802)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723244 sequences (100000074 bp) in 3.632 CPU sec, 3.674 real sec...
[M::process] read 722940 sequences (100000206 bp) in 2.316 CPU sec, 2.318 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (104, 286798, 76, 132)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 366, 1505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4085)
[M::mem_pestat] mean and std.dev: (675.46, 771.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5375)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 522)
[M::mem_pestat] mean and std.dev: (204.34, 95.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 652)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 645, 2241)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6243)
[M::mem_pestat] mean and std.dev: (999.19, 1086.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8244)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 438, 1034)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2602)
[M::mem_pestat] mean and std.dev: (516.12, 442.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3386)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724040 reads in 239.253 CPU sec, 7.590 real sec
sorting block 48, #reads = 1076904 mem = 536880352 peak = 1105027072
[M::mem_process_seqs] Processed 723308 reads in 280.766 CPU sec, 8.947 real sec
sorting block 49, #reads = 1077186 mem = 536881026 peak = 1159819264
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 286507, 85, 129)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 325, 1014)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2646)
[M::mem_pestat] mean and std.dev: (584.70, 575.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3462)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 184, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 516)
[M::mem_pestat] mean and std.dev: (203.14, 93.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 644)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 521, 1166)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3154)
[M::mem_pestat] mean and std.dev: (555.23, 592.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4148)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 438, 860)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2160)
[M::mem_pestat] mean and std.dev: (550.07, 452.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2810)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723366 sequences (100000211 bp) in 3.222 CPU sec, 3.259 real sec...
[M::process] read 722762 sequences (100000290 bp) in 2.194 CPU sec, 2.204 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (103, 285926, 63, 109)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 343, 1144)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3038)
[M::mem_pestat] mean and std.dev: (627.20, 692.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3985)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 519)
[M::mem_pestat] mean and std.dev: (203.85, 94.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 648)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 337, 1088)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2906)
[M::mem_pestat] mean and std.dev: (599.49, 581.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3815)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 425, 2364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6578)
[M::mem_pestat] mean and std.dev: (1116.57, 1324.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8685)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723244 reads in 242.083 CPU sec, 7.679 real sec
[M::process] read 722732 sequences (100000076 bp) in 2.710 CPU sec, 2.714 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (85, 286201, 64, 97)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (304, 488, 925)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2167)
[M::mem_pestat] mean and std.dev: (551.53, 371.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2788)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 519)
[M::mem_pestat] mean and std.dev: (203.85, 94.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 648)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 741, 1456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3920)
[M::mem_pestat] mean and std.dev: (916.22, 931.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5152)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 496, 811)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1963)
[M::mem_pestat] mean and std.dev: (532.88, 424.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2539)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 722762 reads in 137.034 CPU sec, 4.357 real sec
sorting block 50, #reads = 1078153 mem = 536879523 peak = 1159819264
[M::mem_process_seqs] Processed 722940 reads in 346.959 CPU sec, 11.054 real sec
sorting block 51, #reads = 1075273 mem = 536883432 peak = 1159819264
[M::process] read 723458 sequences (100000016 bp) in 3.628 CPU sec, 3.695 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (100, 285929, 68, 135)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 533, 1029)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2695)
[M::mem_pestat] mean and std.dev: (595.00, 450.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3528)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 522)
[M::mem_pestat] mean and std.dev: (204.31, 94.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 652)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 415, 923)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2411)
[M::mem_pestat] mean and std.dev: (501.24, 469.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3155)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 353, 1018)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2706)
[M::mem_pestat] mean and std.dev: (583.94, 612.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3550)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723400 sequences (100000252 bp) in 2.554 CPU sec, 2.563 real sec...
[M::mem_process_seqs] Processed 722732 reads in 148.293 CPU sec, 4.671 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (110, 286541, 86, 106)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 506, 1472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3994)
[M::mem_pestat] mean and std.dev: (723.17, 744.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5255)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 184, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 519)
[M::mem_pestat] mean and std.dev: (203.37, 94.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 648)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 575, 1201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3229)
[M::mem_pestat] mean and std.dev: (712.63, 677.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4243)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 327, 899)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2295)
[M::mem_pestat] mean and std.dev: (534.62, 545.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2993)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (101, 286407, 59, 118)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 380, 752)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1870)
[M::mem_pestat] mean and std.dev: (516.76, 437.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2429)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 184, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 519)
[M::mem_pestat] mean and std.dev: (203.52, 94.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 648)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (262, 615, 1104)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2788)
[M::mem_pestat] mean and std.dev: (691.61, 607.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3630)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 380, 785)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1889)
[M::mem_pestat] mean and std.dev: (429.91, 307.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2441)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723366 reads in 523.393 CPU sec, 16.586 real sec
[M::process] read 722430 sequences (100000252 bp) in 3.152 CPU sec, 3.159 real sec...
sorting block 52, #reads = 1076856 mem = 536876734 peak = 1159819264
[M::mem_process_seqs] Processed 723458 reads in 221.071 CPU sec, 7.037 real sec
sorting block 53, #reads = 1077404 mem = 536882537 peak = 1167380480
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (112, 286654, 80, 98)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 480, 1051)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2705)
[M::mem_pestat] mean and std.dev: (610.12, 522.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3532)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 184, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 516)
[M::mem_pestat] mean and std.dev: (203.13, 93.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 644)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (459, 785, 1794)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4464)
[M::mem_pestat] mean and std.dev: (1162.01, 1099.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5799)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 503, 961)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2407)
[M::mem_pestat] mean and std.dev: (634.37, 498.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3130)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722348 sequences (100000024 bp) in 3.331 CPU sec, 3.422 real sec...
[M::process] read 721822 sequences (100000080 bp) in 2.564 CPU sec, 2.574 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (97, 286274, 65, 122)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 517, 1169)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3033)
[M::mem_pestat] mean and std.dev: (705.08, 695.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3965)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 519)
[M::mem_pestat] mean and std.dev: (204.03, 93.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 648)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 547, 1126)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2964)
[M::mem_pestat] mean and std.dev: (672.66, 576.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3883)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (271, 543, 1075)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2683)
[M::mem_pestat] mean and std.dev: (665.83, 535.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3487)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723400 reads in 239.879 CPU sec, 7.609 real sec
sorting block 54, #reads = 1076237 mem = 536878325 peak = 1167380480
[M::process] read 721762 sequences (100000272 bp) in 2.752 CPU sec, 2.765 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (81, 285848, 69, 113)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 320, 531)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1173)
[M::mem_pestat] mean and std.dev: (371.85, 240.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1494)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 187, 264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 526)
[M::mem_pestat] mean and std.dev: (205.84, 95.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 657)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 664, 1230)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3410)
[M::mem_pestat] mean and std.dev: (665.74, 689.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4500)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 430, 1134)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2994)
[M::mem_pestat] mean and std.dev: (657.15, 603.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3924)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 721822 reads in 138.412 CPU sec, 4.388 real sec
[M::mem_process_seqs] Processed 722430 reads in 349.873 CPU sec, 11.132 real sec
sorting block 55, #reads = 1076218 mem = 536879168 peak = 1167380480
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (101, 286619, 102, 87)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 402, 749)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1825)
[M::mem_pestat] mean and std.dev: (499.23, 396.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2363)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 186, 263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 525)
[M::mem_pestat] mean and std.dev: (205.27, 95.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 656)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (249, 553, 1152)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2958)
[M::mem_pestat] mean and std.dev: (661.83, 581.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3861)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 513, 1007)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2511)
[M::mem_pestat] mean and std.dev: (630.70, 498.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3263)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721462 sequences (100000041 bp) in 3.676 CPU sec, 3.760 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (109, 285589, 83, 85)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 480, 1177)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3179)
[M::mem_pestat] mean and std.dev: (675.72, 611.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4180)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 187, 265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 529)
[M::mem_pestat] mean and std.dev: (206.44, 95.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 661)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (361, 765, 1599)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4075)
[M::mem_pestat] mean and std.dev: (966.20, 866.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5313)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (286, 555, 1354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3490)
[M::mem_pestat] mean and std.dev: (774.17, 670.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4558)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 730582 sequences (100000145 bp) in 2.664 CPU sec, 2.701 real sec...
[M::mem_process_seqs] Processed 722348 reads in 390.150 CPU sec, 12.410 real sec
[M::mem_process_seqs] Processed 721762 reads in 193.022 CPU sec, 6.228 real sec
sorting block 56, #reads = 1077025 mem = 536879352 peak = 1167380480
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (118, 286148, 78, 117)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 404, 828)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2028)
[M::mem_pestat] mean and std.dev: (531.93, 420.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2628)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 187, 266)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 532)
[M::mem_pestat] mean and std.dev: (206.89, 96.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 665)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 433, 737)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1923)
[M::mem_pestat] mean and std.dev: (462.23, 390.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2516)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 394, 1033)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2607)
[M::mem_pestat] mean and std.dev: (614.80, 572.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3394)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 730038 sequences (100000172 bp) in 3.321 CPU sec, 3.432 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (81, 288727, 58, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 331, 1125)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2983)
[M::mem_pestat] mean and std.dev: (648.18, 702.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3912)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 175, 244)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 478)
[M::mem_pestat] mean and std.dev: (192.25, 86.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 595)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 869, 1267)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3355)
[M::mem_pestat] mean and std.dev: (758.46, 631.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4399)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (260, 566, 821)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1943)
[M::mem_pestat] mean and std.dev: (572.38, 400.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2504)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 730040 sequences (100000124 bp) in 2.540 CPU sec, 2.543 real sec...
[M::mem_process_seqs] Processed 721462 reads in 254.271 CPU sec, 8.121 real sec
sorting block 57, #reads = 1076174 mem = 536877723 peak = 1167380480
[M::process] read 729030 sequences (100000071 bp) in 2.566 CPU sec, 2.574 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 289591, 72, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 419, 1004)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2598)
[M::mem_pestat] mean and std.dev: (557.47, 461.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3395)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 175, 246)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 484)
[M::mem_pestat] mean and std.dev: (193.04, 87.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 603)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (130, 407, 1792)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5116)
[M::mem_pestat] mean and std.dev: (931.86, 1173.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6778)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 454, 1076)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2778)
[M::mem_pestat] mean and std.dev: (605.60, 531.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3629)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 730038 reads in 142.163 CPU sec, 4.509 real sec
sorting block 58, #reads = 1079155 mem = 536880316 peak = 1167380480
[M::mem_process_seqs] Processed 730582 reads in 379.817 CPU sec, 12.085 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (81, 289078, 49, 100)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 327, 1009)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2677)
[M::mem_pestat] mean and std.dev: (543.55, 501.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3511)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 176, 247)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 487)
[M::mem_pestat] mean and std.dev: (193.92, 88.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 607)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (263, 618, 1403)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3683)
[M::mem_pestat] mean and std.dev: (816.80, 770.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4823)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 349, 1095)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2809)
[M::mem_pestat] mean and std.dev: (613.41, 612.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3666)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727028 sequences (100000018 bp) in 3.374 CPU sec, 3.416 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (85, 288878, 46, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 387, 1041)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2629)
[M::mem_pestat] mean and std.dev: (620.80, 505.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3423)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 178, 250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 494)
[M::mem_pestat] mean and std.dev: (195.96, 89.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 616)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 578, 1083)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2931)
[M::mem_pestat] mean and std.dev: (642.82, 586.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3855)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 512, 1003)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2611)
[M::mem_pestat] mean and std.dev: (631.73, 541.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3415)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727238 sequences (100000086 bp) in 2.728 CPU sec, 2.730 real sec...
[M::mem_process_seqs] Processed 730040 reads in 292.752 CPU sec, 9.290 real sec
sorting block 59, #reads = 1079558 mem = 536880390 peak = 1167380480
[M::mem_process_seqs] Processed 729030 reads in 188.603 CPU sec, 5.959 real sec
sorting block 60, #reads = 1079433 mem = 536879412 peak = 1167380480
[M::process] read 727522 sequences (100000165 bp) in 3.648 CPU sec, 3.728 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (101, 288464, 42, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 336, 1022)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2740)
[M::mem_pestat] mean and std.dev: (473.26, 451.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3599)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 504)
[M::mem_pestat] mean and std.dev: (198.84, 92.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 629)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (47, 284, 1278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3740)
[M::mem_pestat] mean and std.dev: (753.54, 962.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4971)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 536, 1288)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3350)
[M::mem_pestat] mean and std.dev: (799.04, 795.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4381)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 730604 sequences (100000132 bp) in 2.577 CPU sec, 2.582 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (101, 288942, 52, 93)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 454, 1055)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2689)
[M::mem_pestat] mean and std.dev: (649.84, 588.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3506)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 504)
[M::mem_pestat] mean and std.dev: (198.86, 91.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 629)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (323, 577, 1058)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2528)
[M::mem_pestat] mean and std.dev: (591.64, 479.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3263)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 383, 862)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2124)
[M::mem_pestat] mean and std.dev: (528.54, 393.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2755)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 727238 reads in 252.734 CPU sec, 8.216 real sec
[M::mem_process_seqs] Processed 727028 reads in 291.979 CPU sec, 9.499 real sec
sorting block 61, #reads = 1078873 mem = 536877282 peak = 1167380480
[M::process] read 730578 sequences (100000079 bp) in 3.183 CPU sec, 3.234 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (99, 288725, 56, 115)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 338, 1164)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3086)
[M::mem_pestat] mean and std.dev: (639.63, 694.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4047)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 501)
[M::mem_pestat] mean and std.dev: (198.06, 91.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 625)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (293, 747, 1643)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4343)
[M::mem_pestat] mean and std.dev: (976.67, 1043.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5693)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 373, 1442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3900)
[M::mem_pestat] mean and std.dev: (702.19, 698.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5129)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 730344 sequences (100000130 bp) in 2.280 CPU sec, 2.286 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (108, 289772, 66, 98)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 710, 1176)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3152)
[M::mem_pestat] mean and std.dev: (720.54, 609.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4140)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 175, 247)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 487)
[M::mem_pestat] mean and std.dev: (193.56, 88.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 607)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (306, 539, 1563)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4077)
[M::mem_pestat] mean and std.dev: (949.11, 1045.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5334)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 371, 1056)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2726)
[M::mem_pestat] mean and std.dev: (578.20, 521.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3561)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 289416, 77, 107)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 315, 737)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1801)
[M::mem_pestat] mean and std.dev: (415.94, 332.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2333)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 175, 247)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 487)
[M::mem_pestat] mean and std.dev: (193.71, 88.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 607)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (315, 849, 1917)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5121)
[M::mem_pestat] mean and std.dev: (1016.49, 830.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6723)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 396, 1035)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2611)
[M::mem_pestat] mean and std.dev: (518.18, 442.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3399)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 727522 reads in 354.750 CPU sec, 11.307 real sec
sorting block 62, #reads = 1079857 mem = 536885369 peak = 1167380480
[M::mem_process_seqs] Processed 730578 reads in 288.759 CPU sec, 9.248 real sec
[M::mem_process_seqs] Processed 730604 reads in 330.487 CPU sec, 10.590 real sec
sorting block 63, #reads = 1079180 mem = 536881653 peak = 1167380480
[M::process] read 729614 sequences (100000180 bp) in 4.060 CPU sec, 4.149 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (107, 289270, 47, 111)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 437, 1376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3738)
[M::mem_pestat] mean and std.dev: (804.38, 912.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4919)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 176, 247)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 487)
[M::mem_pestat] mean and std.dev: (193.90, 88.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 607)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 354, 967)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2485)
[M::mem_pestat] mean and std.dev: (439.20, 397.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3244)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 350, 940)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2426)
[M::mem_pestat] mean and std.dev: (600.17, 607.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3169)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728036 sequences (100000164 bp) in 2.965 CPU sec, 3.004 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (101, 288422, 66, 89)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 429, 1026)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2692)
[M::mem_pestat] mean and std.dev: (660.67, 620.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3525)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 177, 249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 493)
[M::mem_pestat] mean and std.dev: (195.01, 89.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 615)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 720, 1325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3525)
[M::mem_pestat] mean and std.dev: (850.21, 776.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4625)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (263, 496, 960)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2354)
[M::mem_pestat] mean and std.dev: (650.68, 534.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3051)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728648 sequences (100000250 bp) in 2.560 CPU sec, 2.557 real sec...
[M::mem_process_seqs] Processed 730344 reads in 275.683 CPU sec, 8.751 real sec
sorting block 64, #reads = 1079252 mem = 536882610 peak = 1167380480
[M::process] read 731274 sequences (100000234 bp) in 2.760 CPU sec, 2.764 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (89, 287802, 69, 94)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 316, 796)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2064)
[M::mem_pestat] mean and std.dev: (466.83, 417.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2698)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 178, 251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 497)
[M::mem_pestat] mean and std.dev: (196.61, 90.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 620)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (262, 586, 946)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2314)
[M::mem_pestat] mean and std.dev: (494.97, 369.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2998)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 427, 964)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2384)
[M::mem_pestat] mean and std.dev: (600.34, 489.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3094)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 728648 reads in 155.750 CPU sec, 4.954 real sec
[M::mem_process_seqs] Processed 729614 reads in 386.599 CPU sec, 12.272 real sec
sorting block 65, #reads = 1075107 mem = 536882745 peak = 1167380480
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (100, 288309, 79, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 465, 1097)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2831)
[M::mem_pestat] mean and std.dev: (429.93, 307.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3698)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 179, 252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 500)
[M::mem_pestat] mean and std.dev: (197.32, 90.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 624)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 725, 1283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3517)
[M::mem_pestat] mean and std.dev: (806.40, 774.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4634)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 581, 1180)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3028)
[M::mem_pestat] mean and std.dev: (728.28, 598.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3952)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728442 sequences (100000292 bp) in 3.640 CPU sec, 3.696 real sec...
[M::process] read 726728 sequences (100000011 bp) in 2.590 CPU sec, 2.589 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (106, 288511, 57, 98)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 443, 1066)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2746)
[M::mem_pestat] mean and std.dev: (549.30, 500.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3586)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (126, 175, 246)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 486)
[M::mem_pestat] mean and std.dev: (193.05, 88.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 606)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 517, 1109)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3009)
[M::mem_pestat] mean and std.dev: (683.30, 686.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3959)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (279, 547, 1077)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2673)
[M::mem_pestat] mean and std.dev: (657.66, 552.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3471)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 728036 reads in 429.938 CPU sec, 13.647 real sec
sorting block 66, #reads = 1076816 mem = 536886357 peak = 1167380480
[M::mem_process_seqs] Processed 731274 reads in 220.460 CPU sec, 7.010 real sec
[M::process] read 727242 sequences (100000071 bp) in 3.169 CPU sec, 3.235 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (101, 287613, 61, 95)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 387, 995)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2543)
[M::mem_pestat] mean and std.dev: (572.76, 486.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3317)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 180, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 504)
[M::mem_pestat] mean and std.dev: (198.88, 91.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 629)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 964, 2305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6467)
[M::mem_pestat] mean and std.dev: (1168.91, 1112.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8548)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 430, 1212)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3248)
[M::mem_pestat] mean and std.dev: (753.84, 779.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4266)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726948 sequences (100000055 bp) in 2.290 CPU sec, 2.294 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (105, 287777, 72, 106)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 349, 903)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2297)
[M::mem_pestat] mean and std.dev: (559.03, 467.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2994)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 178, 251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 497)
[M::mem_pestat] mean and std.dev: (196.54, 90.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 620)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 442, 1272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3380)
[M::mem_pestat] mean and std.dev: (678.18, 668.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4434)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 381, 822)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2142)
[M::mem_pestat] mean and std.dev: (452.99, 413.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2802)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 726728 reads in 274.141 CPU sec, 8.706 real sec
sorting block 67, #reads = 1070153 mem = 536882399 peak = 1167380480
[M::mem_process_seqs] Processed 728442 reads in 321.391 CPU sec, 10.234 real sec
sorting block 68, #reads = 1073744 mem = 536881370 peak = 1215483904
[M::process] read 726994 sequences (100000074 bp) in 3.480 CPU sec, 3.538 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (103, 286977, 76, 93)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 354, 970)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2534)
[M::mem_pestat] mean and std.dev: (593.59, 526.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3316)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 501)
[M::mem_pestat] mean and std.dev: (197.96, 90.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 625)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (298, 693, 1470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3814)
[M::mem_pestat] mean and std.dev: (794.23, 739.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4986)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 399, 829)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2073)
[M::mem_pestat] mean and std.dev: (498.42, 435.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2695)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728894 sequences (100000032 bp) in 2.831 CPU sec, 2.839 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (103, 287270, 76, 85)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 380, 1154)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3080)
[M::mem_pestat] mean and std.dev: (663.70, 732.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4043)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 180, 253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 501)
[M::mem_pestat] mean and std.dev: (198.24, 91.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 625)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (255, 595, 1447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3831)
[M::mem_pestat] mean and std.dev: (833.42, 928.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5023)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 465, 1370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3662)
[M::mem_pestat] mean and std.dev: (729.71, 769.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4808)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (101, 287405, 80, 114)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 340, 839)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2151)
[M::mem_pestat] mean and std.dev: (432.53, 328.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2807)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 180, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 504)
[M::mem_pestat] mean and std.dev: (198.47, 91.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 629)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 489, 945)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2497)
[M::mem_pestat] mean and std.dev: (547.85, 522.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3273)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (297, 566, 1254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3168)
[M::mem_pestat] mean and std.dev: (805.27, 659.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4125)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 727242 reads in 388.114 CPU sec, 12.362 real sec
sorting block 69, #reads = 1070848 mem = 536886460 peak = 1215483904
[M::mem_process_seqs] Processed 726994 reads in 314.214 CPU sec, 10.072 real sec
[M::mem_process_seqs] Processed 726948 reads in 360.654 CPU sec, 11.560 real sec
[M::process] read 735236 sequences (100000103 bp) in 3.598 CPU sec, 3.682 real sec...
sorting block 70, #reads = 1070314 mem = 536881620 peak = 1215483904
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (102, 287782, 71, 89)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 327, 946)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2488)
[M::mem_pestat] mean and std.dev: (508.70, 499.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3259)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 177, 249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 491)
[M::mem_pestat] mean and std.dev: (195.07, 88.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 612)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (286, 594, 1515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3973)
[M::mem_pestat] mean and std.dev: (838.49, 756.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5202)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (297, 480, 1288)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3270)
[M::mem_pestat] mean and std.dev: (809.00, 739.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4261)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 730702 sequences (100000166 bp) in 3.132 CPU sec, 3.154 real sec...
[M::process] read 730860 sequences (100000199 bp) in 2.590 CPU sec, 2.598 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 290032, 65, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (257, 604, 1658)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4460)
[M::mem_pestat] mean and std.dev: (964.89, 994.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5861)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (124, 170, 237)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 463)
[M::mem_pestat] mean and std.dev: (186.52, 82.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 576)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 599, 1133)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2963)
[M::mem_pestat] mean and std.dev: (731.75, 737.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3878)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 307, 698)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1712)
[M::mem_pestat] mean and std.dev: (401.08, 327.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2219)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 728894 reads in 299.894 CPU sec, 9.514 real sec
sorting block 71, #reads = 1072152 mem = 536881264 peak = 1215483904
[M::mem_process_seqs] Processed 735236 reads in 225.166 CPU sec, 7.144 real sec
[M::process] read 729010 sequences (100000293 bp) in 3.207 CPU sec, 3.272 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (85, 289081, 55, 103)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 379, 1288)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3520)
[M::mem_pestat] mean and std.dev: (568.21, 635.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4636)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 176, 247)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 487)
[M::mem_pestat] mean and std.dev: (193.59, 88.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 607)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 515, 1281)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3473)
[M::mem_pestat] mean and std.dev: (678.22, 699.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4569)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 498, 1214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3204)
[M::mem_pestat] mean and std.dev: (757.45, 732.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4199)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727876 sequences (100000000 bp) in 2.788 CPU sec, 2.791 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (97, 289894, 63, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 358, 805)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2041)
[M::mem_pestat] mean and std.dev: (446.21, 425.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2659)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 175, 245)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 481)
[M::mem_pestat] mean and std.dev: (192.42, 87.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 599)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (249, 587, 1267)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3303)
[M::mem_pestat] mean and std.dev: (771.44, 634.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4321)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 435, 1442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3918)
[M::mem_pestat] mean and std.dev: (924.66, 1057.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5156)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 730860 reads in 277.540 CPU sec, 8.797 real sec
sorting block 72, #reads = 1070099 mem = 536884807 peak = 1215483904
[M::process] read 727192 sequences (100000031 bp) in 3.038 CPU sec, 3.045 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (87, 288711, 44, 102)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 363, 909)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2329)
[M::mem_pestat] mean and std.dev: (487.31, 397.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3039)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 177, 250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 494)
[M::mem_pestat] mean and std.dev: (196.11, 90.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 616)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (338, 634, 1742)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4550)
[M::mem_pestat] mean and std.dev: (951.14, 999.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5954)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 582, 1258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3314)
[M::mem_pestat] mean and std.dev: (811.94, 730.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4342)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 729010 reads in 153.802 CPU sec, 4.887 real sec
sorting block 73, #reads = 1072926 mem = 536879965 peak = 1215483904
[M::mem_process_seqs] Processed 730702 reads in 515.182 CPU sec, 16.392 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (115, 288729, 59, 113)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 445, 772)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1952)
[M::mem_pestat] mean and std.dev: (521.49, 466.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2542)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 498)
[M::mem_pestat] mean and std.dev: (197.62, 91.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 621)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 648, 1259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3295)
[M::mem_pestat] mean and std.dev: (700.40, 622.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4313)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 557, 1584)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4268)
[M::mem_pestat] mean and std.dev: (886.83, 930.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5610)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 729294 sequences (100000106 bp) in 3.808 CPU sec, 3.870 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (98, 288150, 70, 85)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (266, 486, 1891)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5141)
[M::mem_pestat] mean and std.dev: (920.84, 1078.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6766)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 180, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 504)
[M::mem_pestat] mean and std.dev: (198.94, 91.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 629)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 405, 993)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2689)
[M::mem_pestat] mean and std.dev: (571.77, 543.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3537)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (273, 461, 1877)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5085)
[M::mem_pestat] mean and std.dev: (1093.86, 1150.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6689)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728896 sequences (100000195 bp) in 2.600 CPU sec, 2.600 real sec...
[M::mem_process_seqs] Processed 727876 reads in 415.967 CPU sec, 13.187 real sec
sorting block 74, #reads = 1075477 mem = 536877021 peak = 1215483904
[M::mem_process_seqs] Processed 727192 reads in 190.376 CPU sec, 6.037 real sec
sorting block 75, #reads = 1076578 mem = 536879985 peak = 1215483904
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 288888, 58, 109)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 306, 1608)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4458)
[M::mem_pestat] mean and std.dev: (689.26, 850.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5883)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 177, 248)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 488)
[M::mem_pestat] mean and std.dev: (194.65, 88.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 608)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (104, 370, 857)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2363)
[M::mem_pestat] mean and std.dev: (530.85, 549.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3116)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 351, 876)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2290)
[M::mem_pestat] mean and std.dev: (438.56, 376.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2997)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 729100 sequences (100000152 bp) in 3.257 CPU sec, 3.321 real sec...
[M::process] read 728808 sequences (100000245 bp) in 2.356 CPU sec, 2.358 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (103, 289169, 73, 91)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 438, 1018)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2690)
[M::mem_pestat] mean and std.dev: (652.39, 597.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3526)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 177, 250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 494)
[M::mem_pestat] mean and std.dev: (195.87, 89.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 616)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (516, 829, 1470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3378)
[M::mem_pestat] mean and std.dev: (932.23, 724.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4332)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 401, 1247)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3381)
[M::mem_pestat] mean and std.dev: (687.67, 621.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4448)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 729294 reads in 255.451 CPU sec, 8.103 real sec
[M::mem_process_seqs] Processed 728896 reads in 185.922 CPU sec, 5.928 real sec
sorting block 76, #reads = 1078627 mem = 536877061 peak = 1215483904
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 289094, 68, 113)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 515, 1092)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2788)
[M::mem_pestat] mean and std.dev: (692.31, 605.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3636)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 177, 250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 494)
[M::mem_pestat] mean and std.dev: (195.71, 89.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 616)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (381, 745, 1187)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2799)
[M::mem_pestat] mean and std.dev: (696.85, 508.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3605)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 424, 1205)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3237)
[M::mem_pestat] mean and std.dev: (637.28, 611.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4253)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728880 sequences (100000138 bp) in 3.690 CPU sec, 3.733 real sec...
[M::process] read 729840 sequences (100000050 bp) in 2.437 CPU sec, 2.437 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (101, 288570, 64, 121)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 420, 971)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2453)
[M::mem_pestat] mean and std.dev: (561.32, 482.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3194)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 177, 249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 491)
[M::mem_pestat] mean and std.dev: (195.15, 89.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 612)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 490, 1227)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3283)
[M::mem_pestat] mean and std.dev: (674.32, 708.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4311)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 341, 792)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1968)
[M::mem_pestat] mean and std.dev: (468.22, 416.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2556)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 729100 reads in 256.576 CPU sec, 8.131 real sec
sorting block 77, #reads = 1080369 mem = 536880348 peak = 1215483904
[M::mem_process_seqs] Processed 728808 reads in 299.515 CPU sec, 9.526 real sec
[M::process] read 729088 sequences (100000014 bp) in 3.091 CPU sec, 3.155 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (98, 288255, 68, 102)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (278, 506, 959)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2321)
[M::mem_pestat] mean and std.dev: (548.38, 424.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3002)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 177, 249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 491)
[M::mem_pestat] mean and std.dev: (195.49, 89.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 612)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 624, 1010)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2648)
[M::mem_pestat] mean and std.dev: (588.08, 519.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3467)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 452, 984)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2490)
[M::mem_pestat] mean and std.dev: (631.57, 551.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3243)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726526 sequences (100000115 bp) in 2.170 CPU sec, 2.169 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (108, 288001, 70, 108)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 449, 1035)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2681)
[M::mem_pestat] mean and std.dev: (672.03, 617.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3504)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 176, 248)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 490)
[M::mem_pestat] mean and std.dev: (194.40, 88.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 611)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 454, 862)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2286)
[M::mem_pestat] mean and std.dev: (457.02, 411.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2998)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 525, 1219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3181)
[M::mem_pestat] mean and std.dev: (775.90, 717.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4162)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (101, 287767, 82, 103)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 415, 1361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3605)
[M::mem_pestat] mean and std.dev: (773.82, 766.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4727)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 177, 249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 491)
[M::mem_pestat] mean and std.dev: (195.02, 89.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 612)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (363, 743, 1395)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3459)
[M::mem_pestat] mean and std.dev: (908.62, 705.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4491)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 370, 830)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2012)
[M::mem_pestat] mean and std.dev: (448.18, 368.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2603)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 728880 reads in 392.396 CPU sec, 12.530 real sec
sorting block 78, #reads = 1077457 mem = 536877953 peak = 1215483904
[M::mem_process_seqs] Processed 729840 reads in 324.531 CPU sec, 10.418 real sec
[M::mem_process_seqs] Processed 729088 reads in 373.825 CPU sec, 11.984 real sec
sorting block 79, #reads = 1075375 mem = 536881020 peak = 1217187840
[M::process] read 726708 sequences (100000086 bp) in 3.590 CPU sec, 3.690 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (90, 287596, 57, 129)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 394, 906)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2304)
[M::mem_pestat] mean and std.dev: (545.20, 458.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3003)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 180, 253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 501)
[M::mem_pestat] mean and std.dev: (198.42, 91.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 625)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (306, 478, 1465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3783)
[M::mem_pestat] mean and std.dev: (781.65, 716.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4942)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 491, 1141)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2949)
[M::mem_pestat] mean and std.dev: (606.50, 503.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3853)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 80, #reads = 1067924 mem = 536877869 peak = 1217187840
[M::process] read 726434 sequences (100000146 bp) in 3.182 CPU sec, 3.248 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (96, 287607, 48, 114)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 534, 1412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3748)
[M::mem_pestat] mean and std.dev: (784.94, 786.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4916)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 180, 253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 501)
[M::mem_pestat] mean and std.dev: (198.40, 91.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 625)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 561, 2009)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5629)
[M::mem_pestat] mean and std.dev: (968.41, 1147.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7439)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 404, 909)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2265)
[M::mem_pestat] mean and std.dev: (528.41, 463.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2943)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726042 sequences (100000069 bp) in 2.527 CPU sec, 2.537 real sec...
[M::mem_process_seqs] Processed 726526 reads in 263.847 CPU sec, 8.370 real sec
[M::mem_process_seqs] Processed 726708 reads in 190.966 CPU sec, 6.037 real sec
sorting block 81, #reads = 1076958 mem = 536883686 peak = 1217187840
[M::process] read 725724 sequences (100000140 bp) in 3.596 CPU sec, 3.674 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (97, 287072, 71, 102)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 673, 1452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3962)
[M::mem_pestat] mean and std.dev: (882.46, 877.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5217)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 508)
[M::mem_pestat] mean and std.dev: (199.88, 92.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 634)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 542, 1934)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5374)
[M::mem_pestat] mean and std.dev: (1084.28, 1330.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7094)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 414, 857)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2115)
[M::mem_pestat] mean and std.dev: (579.93, 511.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2744)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725908 sequences (100000094 bp) in 2.670 CPU sec, 2.673 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (90, 287601, 52, 107)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 445, 905)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2283)
[M::mem_pestat] mean and std.dev: (569.59, 490.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2972)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 180, 255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 505)
[M::mem_pestat] mean and std.dev: (199.27, 92.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 630)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 577, 961)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2423)
[M::mem_pestat] mean and std.dev: (614.53, 507.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3154)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 457, 917)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2319)
[M::mem_pestat] mean and std.dev: (545.56, 456.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3020)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 726042 reads in 256.457 CPU sec, 8.119 real sec
sorting block 82, #reads = 1075555 mem = 536884422 peak = 1217187840
[M::mem_process_seqs] Processed 726434 reads in 297.025 CPU sec, 9.437 real sec
[M::process] read 730630 sequences (100000157 bp) in 3.152 CPU sec, 3.205 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (123, 287096, 69, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (255, 604, 1471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3903)
[M::mem_pestat] mean and std.dev: (881.34, 901.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5119)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 505)
[M::mem_pestat] mean and std.dev: (199.29, 91.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 630)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 657, 1266)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3326)
[M::mem_pestat] mean and std.dev: (889.50, 876.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4395)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 390, 670)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1546)
[M::mem_pestat] mean and std.dev: (433.15, 274.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1984)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728170 sequences (100000053 bp) in 2.078 CPU sec, 2.082 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (134, 286364, 78, 105)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 380, 1203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3189)
[M::mem_pestat] mean and std.dev: (590.96, 532.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4182)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 502)
[M::mem_pestat] mean and std.dev: (199.02, 91.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 626)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 549, 1020)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2724)
[M::mem_pestat] mean and std.dev: (618.04, 610.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3576)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 451, 1045)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2727)
[M::mem_pestat] mean and std.dev: (665.01, 663.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3568)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 725724 reads in 272.664 CPU sec, 8.665 real sec
sorting block 83, #reads = 1075728 mem = 536884565 peak = 1217187840
[M::mem_process_seqs] Processed 725908 reads in 324.829 CPU sec, 10.354 real sec
sorting block 84, #reads = 1068416 mem = 536883034 peak = 1217187840
[M::process] read 727490 sequences (100000230 bp) in 2.949 CPU sec, 2.990 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (85, 288918, 58, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 405, 1199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3219)
[M::mem_pestat] mean and std.dev: (701.70, 743.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4229)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 175, 244)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 478)
[M::mem_pestat] mean and std.dev: (191.78, 86.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 595)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (259, 602, 1334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3484)
[M::mem_pestat] mean and std.dev: (822.02, 688.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4559)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 497, 1271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3331)
[M::mem_pestat] mean and std.dev: (725.48, 654.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4361)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726236 sequences (100000231 bp) in 2.230 CPU sec, 2.234 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (84, 288808, 77, 116)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 445, 1387)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3791)
[M::mem_pestat] mean and std.dev: (735.44, 694.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4993)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 178, 250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 494)
[M::mem_pestat] mean and std.dev: (196.12, 89.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 616)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 342, 856)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2148)
[M::mem_pestat] mean and std.dev: (436.87, 405.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2794)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 441, 1072)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2806)
[M::mem_pestat] mean and std.dev: (620.55, 566.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3673)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 730630 reads in 249.158 CPU sec, 7.903 real sec
[M::mem_process_seqs] Processed 728170 reads in 173.932 CPU sec, 5.576 real sec
sorting block 85, #reads = 1074162 mem = 536882553 peak = 1217187840
[M::process] read 725128 sequences (100000178 bp) in 3.141 CPU sec, 3.180 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (93, 288667, 69, 105)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 403, 1289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3449)
[M::mem_pestat] mean and std.dev: (666.62, 562.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4529)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 178, 251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 495)
[M::mem_pestat] mean and std.dev: (196.71, 90.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 617)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (320, 624, 1555)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4025)
[M::mem_pestat] mean and std.dev: (915.84, 819.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5260)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (279, 468, 1373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3561)
[M::mem_pestat] mean and std.dev: (736.26, 722.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4655)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725386 sequences (100000023 bp) in 2.500 CPU sec, 2.503 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 288218, 57, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 504, 1291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3415)
[M::mem_pestat] mean and std.dev: (790.83, 777.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4477)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 508)
[M::mem_pestat] mean and std.dev: (199.94, 92.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 634)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 482, 873)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2167)
[M::mem_pestat] mean and std.dev: (522.30, 468.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2814)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 408, 960)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2386)
[M::mem_pestat] mean and std.dev: (551.99, 479.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3099)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 287544, 68, 94)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 471, 1370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3656)
[M::mem_pestat] mean and std.dev: (795.96, 827.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4799)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 182, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 512)
[M::mem_pestat] mean and std.dev: (201.62, 93.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 639)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 530, 1257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3359)
[M::mem_pestat] mean and std.dev: (704.59, 609.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4410)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 448, 965)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2419)
[M::mem_pestat] mean and std.dev: (651.75, 537.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3146)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 727490 reads in 337.073 CPU sec, 10.738 real sec
sorting block 86, #reads = 1078832 mem = 536879164 peak = 1217187840
[M::mem_process_seqs] Processed 726236 reads in 269.384 CPU sec, 8.618 real sec
[M::mem_process_seqs] Processed 725128 reads in 308.727 CPU sec, 9.882 real sec
sorting block 87, #reads = 1080945 mem = 536881272 peak = 1217187840
[M::process] read 726422 sequences (100000112 bp) in 3.586 CPU sec, 3.650 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (95, 287924, 47, 115)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 542, 1123)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2951)
[M::mem_pestat] mean and std.dev: (763.42, 712.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3865)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 182, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 514)
[M::mem_pestat] mean and std.dev: (201.18, 93.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 642)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (292, 564, 1140)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2836)
[M::mem_pestat] mean and std.dev: (611.60, 526.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3684)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 379, 1067)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2775)
[M::mem_pestat] mean and std.dev: (649.23, 625.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3629)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728918 sequences (100000001 bp) in 3.096 CPU sec, 3.137 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (102, 288004, 59, 92)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 320, 715)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1787)
[M::mem_pestat] mean and std.dev: (446.82, 392.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2323)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 180, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 511)
[M::mem_pestat] mean and std.dev: (200.44, 93.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 638)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 474, 1085)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2799)
[M::mem_pestat] mean and std.dev: (583.33, 509.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3656)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (281, 529, 1300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3338)
[M::mem_pestat] mean and std.dev: (813.07, 758.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4357)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 725386 reads in 242.503 CPU sec, 7.684 real sec
[M::process] read 727860 sequences (100000135 bp) in 2.734 CPU sec, 2.745 real sec...
sorting block 88, #reads = 1079272 mem = 536881191 peak = 1217187840
[M::mem_process_seqs] Processed 726422 reads in 176.622 CPU sec, 5.563 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 289144, 59, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 484, 1137)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2995)
[M::mem_pestat] mean and std.dev: (678.66, 629.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3924)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 177, 248)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 488)
[M::mem_pestat] mean and std.dev: (194.76, 88.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 608)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 441, 1313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3443)
[M::mem_pestat] mean and std.dev: (722.31, 736.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4508)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 534, 1105)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2833)
[M::mem_pestat] mean and std.dev: (609.75, 493.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3697)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727414 sequences (100000011 bp) in 3.230 CPU sec, 3.297 real sec...
[M::process] read 726892 sequences (100000033 bp) in 2.520 CPU sec, 2.518 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (92, 288350, 63, 112)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 611, 1410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3808)
[M::mem_pestat] mean and std.dev: (728.78, 737.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5007)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 178, 252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 498)
[M::mem_pestat] mean and std.dev: (197.07, 90.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 621)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (246, 492, 1214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3150)
[M::mem_pestat] mean and std.dev: (667.58, 578.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4118)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 426, 1061)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2681)
[M::mem_pestat] mean and std.dev: (607.18, 530.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3491)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 728918 reads in 241.006 CPU sec, 7.642 real sec
sorting block 89, #reads = 1080325 mem = 536883459 peak = 1217187840
[M::mem_process_seqs] Processed 727860 reads in 173.881 CPU sec, 5.528 real sec
sorting block 90, #reads = 1080162 mem = 536882234 peak = 1217187840
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (96, 288143, 84, 94)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (275, 647, 1610)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4280)
[M::mem_pestat] mean and std.dev: (842.95, 737.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5615)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 501)
[M::mem_pestat] mean and std.dev: (197.95, 91.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 625)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 729, 1132)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3052)
[M::mem_pestat] mean and std.dev: (674.17, 605.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4012)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (357, 716, 2200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5886)
[M::mem_pestat] mean and std.dev: (1141.21, 1145.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7729)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726126 sequences (100000190 bp) in 3.322 CPU sec, 3.359 real sec...
[M::process] read 725950 sequences (100000151 bp) in 2.560 CPU sec, 2.566 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (95, 287883, 76, 102)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 492, 1623)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4441)
[M::mem_pestat] mean and std.dev: (859.85, 908.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5850)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 180, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 504)
[M::mem_pestat] mean and std.dev: (198.75, 91.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 629)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 498, 1421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3889)
[M::mem_pestat] mean and std.dev: (793.54, 919.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5123)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (272, 395, 853)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2015)
[M::mem_pestat] mean and std.dev: (589.99, 464.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2596)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 727414 reads in 245.631 CPU sec, 7.780 real sec
[M::mem_process_seqs] Processed 726892 reads in 180.382 CPU sec, 5.742 real sec
sorting block 91, #reads = 1078853 mem = 536877727 peak = 1217187840
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (84, 286943, 66, 89)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 423, 927)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2319)
[M::mem_pestat] mean and std.dev: (488.65, 414.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3015)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 180, 255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 505)
[M::mem_pestat] mean and std.dev: (199.44, 92.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 630)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (297, 727, 1493)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3885)
[M::mem_pestat] mean and std.dev: (920.54, 805.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5081)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 500, 1019)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2607)
[M::mem_pestat] mean and std.dev: (573.64, 443.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3401)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727160 sequences (100000008 bp) in 3.256 CPU sec, 3.295 real sec...
[M::process] read 726300 sequences (100000074 bp) in 2.580 CPU sec, 2.580 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (90, 287642, 73, 96)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 415, 1341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3637)
[M::mem_pestat] mean and std.dev: (564.54, 518.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4785)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 505)
[M::mem_pestat] mean and std.dev: (199.34, 91.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 630)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 506, 1273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3525)
[M::mem_pestat] mean and std.dev: (667.96, 688.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4651)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (259, 405, 845)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2017)
[M::mem_pestat] mean and std.dev: (534.10, 425.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2603)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 726126 reads in 246.174 CPU sec, 7.797 real sec
sorting block 92, #reads = 1079229 mem = 536880349 peak = 1217187840
[M::mem_process_seqs] Processed 725950 reads in 179.272 CPU sec, 5.703 real sec
[M::process] read 726126 sequences (100000137 bp) in 3.400 CPU sec, 3.444 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (83, 287300, 83, 87)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 448, 1351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3705)
[M::mem_pestat] mean and std.dev: (702.63, 723.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4882)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 498)
[M::mem_pestat] mean and std.dev: (197.44, 90.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 621)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 646, 1336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3632)
[M::mem_pestat] mean and std.dev: (774.81, 699.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4780)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 495, 1496)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4054)
[M::mem_pestat] mean and std.dev: (862.40, 898.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5333)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726492 sequences (100000241 bp) in 2.590 CPU sec, 2.587 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (94, 287042, 60, 92)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 484, 949)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2493)
[M::mem_pestat] mean and std.dev: (594.53, 549.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3265)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 180, 253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 499)
[M::mem_pestat] mean and std.dev: (197.70, 90.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 622)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 422, 1085)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2917)
[M::mem_pestat] mean and std.dev: (647.80, 633.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3833)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 336, 864)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2226)
[M::mem_pestat] mean and std.dev: (549.90, 574.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2907)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (112, 287153, 73, 105)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 397, 730)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1754)
[M::mem_pestat] mean and std.dev: (479.96, 375.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2266)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 180, 253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 499)
[M::mem_pestat] mean and std.dev: (198.16, 90.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 622)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 464, 1254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3338)
[M::mem_pestat] mean and std.dev: (802.85, 771.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4380)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 459, 914)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2244)
[M::mem_pestat] mean and std.dev: (532.18, 420.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2909)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 727160 reads in 356.636 CPU sec, 11.354 real sec
sorting block 93, #reads = 1076112 mem = 536886656 peak = 1217187840
[M::mem_process_seqs] Processed 726300 reads in 283.643 CPU sec, 9.075 real sec
[M::mem_process_seqs] Processed 726126 reads in 325.388 CPU sec, 10.420 real sec
sorting block 94, #reads = 1072445 mem = 536880148 peak = 1234427904
[M::process] read 726632 sequences (100000113 bp) in 3.479 CPU sec, 3.543 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (101, 286942, 76, 105)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 480, 1291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3455)
[M::mem_pestat] mean and std.dev: (762.62, 750.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4537)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 179, 252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 496)
[M::mem_pestat] mean and std.dev: (197.32, 89.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 618)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 500, 966)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2552)
[M::mem_pestat] mean and std.dev: (523.48, 494.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3345)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 558, 1124)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2874)
[M::mem_pestat] mean and std.dev: (754.69, 643.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3749)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 95, #reads = 1076002 mem = 536879857 peak = 1234427904
[M::process] read 726880 sequences (100000010 bp) in 2.920 CPU sec, 2.955 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (89, 287151, 72, 93)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 563, 1012)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2594)
[M::mem_pestat] mean and std.dev: (608.56, 491.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3385)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 498)
[M::mem_pestat] mean and std.dev: (197.15, 89.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 621)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (302, 647, 1995)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5381)
[M::mem_pestat] mean and std.dev: (1156.07, 1275.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7074)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 552, 1263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3289)
[M::mem_pestat] mean and std.dev: (792.41, 720.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4302)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726274 sequences (100000233 bp) in 2.630 CPU sec, 2.627 real sec...
[M::mem_process_seqs] Processed 726492 reads in 260.502 CPU sec, 8.238 real sec
[M::mem_process_seqs] Processed 726632 reads in 191.520 CPU sec, 6.034 real sec
sorting block 96, #reads = 1075413 mem = 536878192 peak = 1234427904
[M::process] read 733666 sequences (100000006 bp) in 3.683 CPU sec, 3.747 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (95, 287544, 58, 91)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 299, 842)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2216)
[M::mem_pestat] mean and std.dev: (534.98, 499.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2903)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 492)
[M::mem_pestat] mean and std.dev: (196.09, 88.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 613)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 766, 1752)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4954)
[M::mem_pestat] mean and std.dev: (816.84, 739.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6555)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 361, 890)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2258)
[M::mem_pestat] mean and std.dev: (494.24, 449.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2942)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 730482 sequences (100000092 bp) in 2.620 CPU sec, 2.618 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (89, 286621, 66, 103)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 369, 816)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2050)
[M::mem_pestat] mean and std.dev: (478.41, 378.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2667)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 180, 251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 493)
[M::mem_pestat] mean and std.dev: (196.96, 89.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 614)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (132, 516, 926)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2514)
[M::mem_pestat] mean and std.dev: (552.21, 453.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3308)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 401, 1077)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2777)
[M::mem_pestat] mean and std.dev: (603.80, 566.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3627)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 726880 reads in 279.416 CPU sec, 8.856 real sec
sorting block 97, #reads = 1073842 mem = 536887689 peak = 1234427904
[M::mem_process_seqs] Processed 726274 reads in 329.061 CPU sec, 10.463 real sec
[M::process] read 728674 sequences (100000276 bp) in 3.154 CPU sec, 3.190 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (94, 289675, 57, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 426, 934)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2306)
[M::mem_pestat] mean and std.dev: (579.75, 428.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2992)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (125, 171, 238)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 464)
[M::mem_pestat] mean and std.dev: (187.42, 83.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 577)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 512, 1087)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2815)
[M::mem_pestat] mean and std.dev: (596.69, 510.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3679)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 271, 1004)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2604)
[M::mem_pestat] mean and std.dev: (546.66, 516.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3404)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727566 sequences (100000068 bp) in 2.590 CPU sec, 2.588 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (90, 288766, 72, 102)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 473, 1019)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2617)
[M::mem_pestat] mean and std.dev: (617.54, 517.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3416)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 175, 245)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 481)
[M::mem_pestat] mean and std.dev: (192.02, 86.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 599)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (254, 617, 1261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3275)
[M::mem_pestat] mean and std.dev: (690.58, 592.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4282)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 492, 1133)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2961)
[M::mem_pestat] mean and std.dev: (662.13, 626.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3875)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 733666 reads in 270.478 CPU sec, 8.572 real sec
sorting block 98, #reads = 1066952 mem = 536882688 peak = 1234427904
[M::mem_process_seqs] Processed 730482 reads in 313.271 CPU sec, 9.959 real sec
sorting block 99, #reads = 1075673 mem = 536880674 peak = 1234427904
[M::process] read 725906 sequences (100000237 bp) in 3.367 CPU sec, 3.401 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (87, 287931, 74, 91)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 341, 816)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2102)
[M::mem_pestat] mean and std.dev: (444.01, 409.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2745)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 177, 250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 494)
[M::mem_pestat] mean and std.dev: (195.97, 89.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 616)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 658, 1559)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4327)
[M::mem_pestat] mean and std.dev: (881.65, 892.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5711)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 439, 1113)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2855)
[M::mem_pestat] mean and std.dev: (574.00, 530.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3726)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725730 sequences (100000174 bp) in 2.590 CPU sec, 2.592 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 288185, 76, 93)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 328, 726)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1840)
[M::mem_pestat] mean and std.dev: (439.55, 427.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2397)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 498)
[M::mem_pestat] mean and std.dev: (197.56, 90.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 621)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 781, 1385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3699)
[M::mem_pestat] mean and std.dev: (952.36, 989.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4911)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 539, 1270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3336)
[M::mem_pestat] mean and std.dev: (599.34, 593.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4369)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (108, 287835, 56, 105)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (282, 428, 1180)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2976)
[M::mem_pestat] mean and std.dev: (696.15, 626.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3874)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 511)
[M::mem_pestat] mean and std.dev: (200.72, 93.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 638)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 514, 1607)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4549)
[M::mem_pestat] mean and std.dev: (933.20, 1150.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6020)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 375, 772)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1920)
[M::mem_pestat] mean and std.dev: (499.62, 422.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2494)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 728674 reads in 362.272 CPU sec, 11.536 real sec
[M::mem_process_seqs] Processed 727566 reads in 290.439 CPU sec, 9.293 real sec
sorting block 100, #reads = 1076285 mem = 536879483 peak = 1234427904
[M::mem_process_seqs] Processed 725906 reads in 332.094 CPU sec, 10.628 real sec
[M::process] read 727246 sequences (100000161 bp) in 3.302 CPU sec, 3.361 real sec...
sorting block 101, #reads = 1076161 mem = 536878897 peak = 1234427904
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (123, 287553, 67, 92)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 587, 1256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3362)
[M::mem_pestat] mean and std.dev: (596.73, 485.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4415)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 511)
[M::mem_pestat] mean and std.dev: (200.97, 94.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 638)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (283, 707, 1850)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4984)
[M::mem_pestat] mean and std.dev: (1090.26, 1173.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6551)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 386, 739)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1765)
[M::mem_pestat] mean and std.dev: (436.40, 330.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2278)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726054 sequences (100000260 bp) in 3.124 CPU sec, 3.156 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (107, 287716, 63, 113)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 366, 1062)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2792)
[M::mem_pestat] mean and std.dev: (661.90, 635.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3657)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 504)
[M::mem_pestat] mean and std.dev: (198.48, 91.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 629)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 550, 1095)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2959)
[M::mem_pestat] mean and std.dev: (622.20, 555.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3891)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 553, 1444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3910)
[M::mem_pestat] mean and std.dev: (934.83, 913.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5143)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725122 sequences (100000057 bp) in 2.510 CPU sec, 2.505 real sec...
[M::mem_process_seqs] Processed 725730 reads in 253.104 CPU sec, 8.003 real sec
[M::mem_process_seqs] Processed 727246 reads in 182.993 CPU sec, 5.777 real sec
sorting block 102, #reads = 1076240 mem = 536881872 peak = 1234427904
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (91, 287165, 62, 91)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (308, 556, 983)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2333)
[M::mem_pestat] mean and std.dev: (629.93, 438.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3008)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 180, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 502)
[M::mem_pestat] mean and std.dev: (198.97, 91.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 626)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 510, 1099)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2971)
[M::mem_pestat] mean and std.dev: (627.07, 656.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3907)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 390, 968)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2450)
[M::mem_pestat] mean and std.dev: (509.44, 485.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3191)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724550 sequences (100000013 bp) in 3.347 CPU sec, 3.417 real sec...
[M::process] read 724110 sequences (100000083 bp) in 2.570 CPU sec, 2.572 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (104, 286788, 75, 92)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 532, 1153)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3125)
[M::mem_pestat] mean and std.dev: (592.77, 565.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4111)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 182, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 512)
[M::mem_pestat] mean and std.dev: (201.59, 93.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 639)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (286, 572, 998)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2422)
[M::mem_pestat] mean and std.dev: (650.49, 484.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3134)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 377, 966)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2500)
[M::mem_pestat] mean and std.dev: (520.81, 452.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3267)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 726054 reads in 248.399 CPU sec, 7.864 real sec
sorting block 103, #reads = 1078181 mem = 536882449 peak = 1234427904
[M::mem_process_seqs] Processed 725122 reads in 179.466 CPU sec, 5.709 real sec
[M::process] read 723122 sequences (100000095 bp) in 3.396 CPU sec, 3.430 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (131, 286496, 59, 141)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 416, 885)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2229)
[M::mem_pestat] mean and std.dev: (514.19, 432.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2901)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 515)
[M::mem_pestat] mean and std.dev: (202.53, 93.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 643)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (112, 526, 882)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2422)
[M::mem_pestat] mean and std.dev: (494.28, 475.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3192)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 480, 1006)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2536)
[M::mem_pestat] mean and std.dev: (691.66, 631.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3301)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723338 sequences (100000231 bp) in 2.250 CPU sec, 2.252 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (91, 286451, 78, 88)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 450, 1044)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2670)
[M::mem_pestat] mean and std.dev: (678.64, 580.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3483)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 515)
[M::mem_pestat] mean and std.dev: (202.20, 93.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 643)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (372, 698, 1199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2853)
[M::mem_pestat] mean and std.dev: (765.87, 548.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3680)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 629, 1089)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2785)
[M::mem_pestat] mean and std.dev: (716.30, 667.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3633)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724110 reads in 258.969 CPU sec, 8.214 real sec
sorting block 104, #reads = 1076170 mem = 536883437 peak = 1234427904
[M::mem_process_seqs] Processed 724550 reads in 300.655 CPU sec, 9.569 real sec
sorting block 105, #reads = 1072691 mem = 536878390 peak = 1243389952
[M::process] read 722608 sequences (100000118 bp) in 2.863 CPU sec, 2.928 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (103, 285882, 72, 92)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 409, 1079)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2781)
[M::mem_pestat] mean and std.dev: (589.00, 516.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3632)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 184, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 516)
[M::mem_pestat] mean and std.dev: (202.85, 93.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 644)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 581, 1539)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4143)
[M::mem_pestat] mean and std.dev: (781.00, 844.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5445)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 631, 1188)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3120)
[M::mem_pestat] mean and std.dev: (692.17, 598.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4086)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723016 sequences (100000255 bp) in 2.117 CPU sec, 2.126 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (102, 285901, 83, 99)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 360, 840)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2056)
[M::mem_pestat] mean and std.dev: (474.78, 413.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2664)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 184, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 513)
[M::mem_pestat] mean and std.dev: (202.49, 92.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 640)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 470, 929)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2363)
[M::mem_pestat] mean and std.dev: (548.91, 476.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3080)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 391, 1035)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2741)
[M::mem_pestat] mean and std.dev: (555.67, 533.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3594)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (98, 285840, 82, 87)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 488, 893)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2251)
[M::mem_pestat] mean and std.dev: (567.03, 478.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2930)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 516)
[M::mem_pestat] mean and std.dev: (203.18, 93.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 644)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 512, 1258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3406)
[M::mem_pestat] mean and std.dev: (609.97, 650.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4480)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (289, 662, 1237)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3133)
[M::mem_pestat] mean and std.dev: (709.60, 598.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4081)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723122 reads in 346.673 CPU sec, 11.057 real sec
[M::mem_process_seqs] Processed 723338 reads in 276.647 CPU sec, 8.877 real sec
sorting block 106, #reads = 1074368 mem = 536877657 peak = 1243389952
[M::mem_process_seqs] Processed 722608 reads in 316.540 CPU sec, 10.158 real sec
[M::process] read 722768 sequences (100000264 bp) in 2.973 CPU sec, 3.015 real sec...
sorting block 107, #reads = 1074184 mem = 536876837 peak = 1243389952
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (108, 285306, 70, 116)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 428, 1052)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2692)
[M::mem_pestat] mean and std.dev: (584.33, 553.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3512)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 184, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 513)
[M::mem_pestat] mean and std.dev: (202.55, 92.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 640)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 383, 710)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1806)
[M::mem_pestat] mean and std.dev: (438.68, 424.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2354)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 440, 1384)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3708)
[M::mem_pestat] mean and std.dev: (735.28, 781.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4870)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722904 sequences (100000094 bp) in 2.951 CPU sec, 3.023 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (96, 285512, 75, 102)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 436, 798)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2034)
[M::mem_pestat] mean and std.dev: (457.08, 341.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2652)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 184, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 510)
[M::mem_pestat] mean and std.dev: (201.97, 91.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 636)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (258, 740, 1510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4014)
[M::mem_pestat] mean and std.dev: (967.58, 927.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5266)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 561, 1163)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3041)
[M::mem_pestat] mean and std.dev: (835.30, 799.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4032)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722770 sequences (100000069 bp) in 1.978 CPU sec, 1.983 real sec...
[M::mem_process_seqs] Processed 723016 reads in 247.323 CPU sec, 7.860 real sec
sorting block 108, #reads = 1075136 mem = 536877790 peak = 1243389952
[M::mem_process_seqs] Processed 722768 reads in 180.917 CPU sec, 5.740 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (95, 285997, 78, 114)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 381, 753)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1865)
[M::mem_pestat] mean and std.dev: (497.48, 430.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2421)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 184, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 513)
[M::mem_pestat] mean and std.dev: (202.69, 92.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 640)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 697, 1110)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3010)
[M::mem_pestat] mean and std.dev: (636.46, 573.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3960)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 541, 1292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3442)
[M::mem_pestat] mean and std.dev: (767.23, 709.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4517)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723018 sequences (100000122 bp) in 3.649 CPU sec, 3.715 real sec...
[M::process] read 723380 sequences (100000200 bp) in 2.560 CPU sec, 2.562 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (87, 285779, 79, 119)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 397, 1061)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2695)
[M::mem_pestat] mean and std.dev: (675.10, 611.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3512)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 516)
[M::mem_pestat] mean and std.dev: (203.27, 93.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 644)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 436, 1184)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3116)
[M::mem_pestat] mean and std.dev: (638.01, 624.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4082)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 405, 782)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1944)
[M::mem_pestat] mean and std.dev: (534.37, 419.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2525)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 722904 reads in 239.266 CPU sec, 7.561 real sec
sorting block 109, #reads = 1074431 mem = 536878155 peak = 1243389952
[M::mem_process_seqs] Processed 722770 reads in 277.521 CPU sec, 8.810 real sec
[M::process] read 226538 sequences (31255851 bp) in 1.322 CPU sec, 1.335 real sec...
sorting block 110, #reads = 1075057 mem = 536885627 peak = 1243389952
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (95, 286723, 59, 90)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 452, 976)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2434)
[M::mem_pestat] mean and std.dev: (646.19, 555.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3163)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 184, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 513)
[M::mem_pestat] mean and std.dev: (202.52, 92.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 640)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 357, 1063)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2817)
[M::mem_pestat] mean and std.dev: (472.31, 464.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3694)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 468, 974)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2470)
[M::mem_pestat] mean and std.dev: (590.01, 507.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3218)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (104, 286421, 71, 94)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (246, 494, 1242)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3234)
[M::mem_pestat] mean and std.dev: (701.27, 735.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4230)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 184, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 513)
[M::mem_pestat] mean and std.dev: (202.47, 92.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 640)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 475, 1170)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3074)
[M::mem_pestat] mean and std.dev: (699.41, 629.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4026)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 450, 1159)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3009)
[M::mem_pestat] mean and std.dev: (684.74, 660.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3934)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 89671, 22, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 670, 1590)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4300)
[M::mem_pestat] mean and std.dev: (805.85, 859.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5655)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 182, 255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 503)
[M::mem_pestat] mean and std.dev: (200.22, 91.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 627)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (254, 932, 1264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3284)
[M::mem_pestat] mean and std.dev: (797.30, 668.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4294)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 265, 938)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2458)
[M::mem_pestat] mean and std.dev: (699.77, 867.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4171)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723018 reads in 267.410 CPU sec, 8.621 real sec
[M::mem_process_seqs] Processed 723380 reads in 207.239 CPU sec, 6.692 real sec
[M::mem_process_seqs] Processed 226538 reads in 221.083 CPU sec, 7.145 real sec
sorting block 111, #reads = 1076283 mem = 536881079 peak = 1243389952
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 00050657
  features: 1f8bfbff fffa320b
  extended: d19f47ab 00000818
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) Platinum 8259CL CPU @ 2.50GHz
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 119897470
overall: 71396548608 mem 24816.665 user 259.246 sys 811.400 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1029_BICJ-T1-TDNA-1_A23MHWWLT4_1.L001\tPU:L001\tSM:1029_BICJ-T1-TDNA-1_A23MHWWLT4_1\tLB:1029_BICJ-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1029_BICJ-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1029_BICJ-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 811.430 sec; CPU: 25075.915 sec
sorting block 112, #reads = 682275 mem = 341265558 peak = 1243389952
uniq header count 1
merging 113 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 00050657
  features: 1f8bfbff fffa320b
  extended: d19f47ab 00000818
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) Platinum 8259CL CPU @ 2.50GHz
threads: 31 max 48
algo: util-sort
license: sentieon:util=1
output file size: 6624839772
output reads: 121239047
bam_mem_sort: 113 calls 109.781 user 0.838 sys 110.840 real
bam_write: 113 calls 66.562 user 4.015 sys 78.823 real
execute: 1 calls 42.779 user 1.132 sys 870.892 real
merge_files: 1 calls 42.736 user 1.102 sys 58.953 real
parse_chunk: 1803 calls 146.313 user 29.870 sys 178.715 real
read_chunk: 4895 calls 72.863 user 45.017 sys 779.705 real
sort_block: 1 calls 47.902 user 43.791 sys 747.864 real
write_chunk: 3090 calls 41.873 user 0.824 sys 57.416 real
overall: 3831853056 mem 2369.065 user 101.609 sys 870.914 real
ls: cannot access '*.cram': No such file or directory