This software is licensed to bgold@natera.com by Sentieon Inc.
cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 659_bgw-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 1456.713 CPU sec, 49.685 real sec
[M::process] read 693904 sequences (100000076 bp) in 0.899 CPU sec, 0.904 real sec...
[M::process] read 693292 sequences (100000035 bp) in 1.460 CPU sec, 1.455 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (7, 288313, 10, 16)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 248, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 722)
[M::mem_pestat] mean and std.dev: (271.33, 131.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 906)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 377, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 879)
[M::mem_pestat] mean and std.dev: (328.20, 167.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1096)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 240, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709)
[M::mem_pestat] mean and std.dev: (244.93, 76.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 878)
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 692876 sequences (100000265 bp) in 1.530 CPU sec, 1.535 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (13, 288513, 2, 17)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (298, 537, 3218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9058)
[M::mem_pestat] mean and std.dev: (1243.31, 1350.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11978)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 250, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 729)
[M::mem_pestat] mean and std.dev: (273.74, 132.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 915)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 348, 1330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3638)
[M::mem_pestat] mean and std.dev: (537.67, 643.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4792)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 693904 reads in 136.826 CPU sec, 4.280 real sec
[M::process] read 692812 sequences (100000095 bp) in 1.560 CPU sec, 1.574 real sec...
[M::mem_process_seqs] Processed 693292 reads in 89.527 CPU sec, 2.810 real sec
sorting block 0, #reads = 1087118 mem = 536882417 peak = 595906560
[M::process] read 692346 sequences (100000263 bp) in 1.824 CPU sec, 1.889 real sec...
[M::process] read 691602 sequences (100000228 bp) in 1.620 CPU sec, 1.620 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (5, 287858, 6, 22)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 250, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 733)
[M::mem_pestat] mean and std.dev: (274.85, 133.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 920)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 351, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 826)
[M::mem_pestat] mean and std.dev: (301.05, 103.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1023)
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 692812 reads in 77.167 CPU sec, 2.436 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 288194, 3, 9)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 457, 638)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1372)
[M::mem_pestat] mean and std.dev: (431.50, 205.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1739)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 251, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 732)
[M::mem_pestat] mean and std.dev: (274.06, 132.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 919)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (18, 288597, 3, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 268, 946)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2492)
[M::mem_pestat] mean and std.dev: (581.33, 507.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3265)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 252, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 740)
[M::mem_pestat] mean and std.dev: (276.95, 134.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 929)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 293, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 998)
[M::mem_pestat] mean and std.dev: (338.80, 182.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1262)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 691130 sequences (100000235 bp) in 1.773 CPU sec, 1.781 real sec...
[M::mem_process_seqs] Processed 692876 reads in 217.159 CPU sec, 6.863 real sec
sorting block 1, #reads = 1086565 mem = 536878046 peak = 727109632
[M::mem_process_seqs] Processed 692346 reads in 167.358 CPU sec, 5.299 real sec
sorting block 2, #reads = 1086441 mem = 536878046 peak = 905527296
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (15, 287715, 9, 15)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 286, 424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 852)
[M::mem_pestat] mean and std.dev: (348.80, 214.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1205)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 254, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 747)
[M::mem_pestat] mean and std.dev: (279.26, 136.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 938)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 243, 286)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (151, 376)
[M::mem_pestat] mean and std.dev: (262.40, 32.48)
[M::mem_pestat] low and high boundaries for proper pairs: (106, 421)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 690374 sequences (100000247 bp) in 2.205 CPU sec, 2.297 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (9, 288011, 8, 7)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 257, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (281.55, 136.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 947)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::process] read 690314 sequences (100000010 bp) in 1.690 CPU sec, 1.681 real sec...
[M::mem_process_seqs] Processed 691602 reads in 139.767 CPU sec, 4.412 real sec
[M::mem_process_seqs] Processed 691130 reads in 89.869 CPU sec, 2.835 real sec
sorting block 3, #reads = 1087154 mem = 536878807 peak = 905527296
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (13, 287494, 9, 7)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 267, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 706)
[M::mem_pestat] mean and std.dev: (225.46, 101.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 894)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 259, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 759)
[M::mem_pestat] mean and std.dev: (283.88, 137.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 953)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::process] read 690124 sequences (100000188 bp) in 2.065 CPU sec, 2.161 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (8, 287066, 2, 18)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 260, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 768)
[M::mem_pestat] mean and std.dev: (285.28, 139.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 965)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 414, 1128)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3070)
[M::mem_pestat] mean and std.dev: (494.27, 370.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4041)
[M::mem_pestat] skip orientation RR
[M::process] read 689872 sequences (100000172 bp) in 1.680 CPU sec, 1.679 real sec...
[M::mem_process_seqs] Processed 690374 reads in 137.560 CPU sec, 4.349 real sec
[M::mem_process_seqs] Processed 690314 reads in 89.185 CPU sec, 2.807 real sec
sorting block 4, #reads = 1085914 mem = 536883081 peak = 905527296
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 287425, 3, 14)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (407, 812, 913)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1925)
[M::mem_pestat] mean and std.dev: (631.83, 286.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2431)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 261, 375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 771)
[M::mem_pestat] mean and std.dev: (286.06, 139.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 969)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 262, 411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 869)
[M::mem_pestat] mean and std.dev: (317.00, 183.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1098)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 689558 sequences (100000186 bp) in 2.112 CPU sec, 2.216 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (16, 287451, 3, 13)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 258, 494)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1068)
[M::mem_pestat] mean and std.dev: (309.94, 170.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1355)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 263, 378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 778)
[M::mem_pestat] mean and std.dev: (288.12, 140.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 978)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 229, 290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (32, 462)
[M::mem_pestat] mean and std.dev: (216.73, 52.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 548)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 690124 reads in 138.632 CPU sec, 4.388 real sec
[M::process] read 689740 sequences (100000194 bp) in 1.720 CPU sec, 1.712 real sec...
sorting block 5, #reads = 1086354 mem = 536877912 peak = 905527296
[M::mem_process_seqs] Processed 689872 reads in 89.281 CPU sec, 2.810 real sec
sorting block 6, #reads = 1086069 mem = 536878200 peak = 905527296
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (16, 286779, 10, 20)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 171, 381)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 821)
[M::mem_pestat] mean and std.dev: (303.62, 227.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1212)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 263, 378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 776)
[M::mem_pestat] mean and std.dev: (288.48, 141.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 975)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (292, 790, 4509)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12943)
[M::mem_pestat] mean and std.dev: (1728.90, 1880.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17160)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 396, 2503)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7191)
[M::mem_pestat] mean and std.dev: (929.25, 1035.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9535)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 689450 sequences (100000203 bp) in 1.955 CPU sec, 2.067 real sec...
[M::process] read 689440 sequences (100000021 bp) in 1.380 CPU sec, 1.375 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (8, 287238, 3, 16)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 263, 376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 772)
[M::mem_pestat] mean and std.dev: (287.13, 139.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 970)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (301, 426, 584)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1150)
[M::mem_pestat] mean and std.dev: (418.64, 184.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1433)
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 689558 reads in 138.642 CPU sec, 4.401 real sec
[M::mem_process_seqs] Processed 689740 reads in 89.192 CPU sec, 2.828 real sec
sorting block 7, #reads = 1085236 mem = 536879922 peak = 905527296
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (17, 287096, 2, 9)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (123, 184, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 522)
[M::mem_pestat] mean and std.dev: (176.44, 61.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 655)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 261, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 766)
[M::mem_pestat] mean and std.dev: (285.90, 139.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 962)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::process] read 689300 sequences (100000011 bp) in 1.977 CPU sec, 2.087 real sec...
[M::process] read 689364 sequences (100000080 bp) in 1.320 CPU sec, 1.322 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (12, 286809, 7, 17)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 256, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 670)
[M::mem_pestat] mean and std.dev: (281.17, 101.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 825)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 261, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 766)
[M::mem_pestat] mean and std.dev: (285.99, 138.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 962)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 380, 478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1076)
[M::mem_pestat] mean and std.dev: (302.67, 155.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1375)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 689450 reads in 138.357 CPU sec, 4.396 real sec
[M::mem_process_seqs] Processed 689440 reads in 89.072 CPU sec, 2.823 real sec
sorting block 8, #reads = 1085831 mem = 536879913 peak = 905527296
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (14, 286953, 8, 13)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (126, 230, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1134)
[M::mem_pestat] mean and std.dev: (280.92, 212.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1470)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 262, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (286.62, 138.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 959)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 276, 556)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1434)
[M::mem_pestat] mean and std.dev: (329.77, 232.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1873)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 689686 sequences (100000009 bp) in 2.518 CPU sec, 2.611 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (10, 287481, 3, 20)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 580, 856)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2220)
[M::mem_pestat] mean and std.dev: (514.50, 390.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2902)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 262, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (286.20, 138.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 959)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (262, 886, 914)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2218)
[M::mem_pestat] mean and std.dev: (582.11, 342.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2870)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 689300 reads in 138.592 CPU sec, 4.378 real sec
[M::process] read 689454 sequences (100000031 bp) in 1.766 CPU sec, 1.784 real sec...
[M::mem_process_seqs] Processed 689364 reads in 89.089 CPU sec, 2.798 real sec
sorting block 9, #reads = 1086215 mem = 536877859 peak = 905527296
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (8, 287175, 12, 13)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 260, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (284.69, 137.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (107, 1475, 3701)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10889)
[M::mem_pestat] mean and std.dev: (1704.83, 1696.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14483)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 240, 1390)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3804)
[M::mem_pestat] mean and std.dev: (544.54, 536.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5011)
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 689306 sequences (100000300 bp) in 2.553 CPU sec, 2.668 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (12, 287586, 6, 13)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 318, 2082)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5948)
[M::mem_pestat] mean and std.dev: (685.75, 810.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7881)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 260, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 766)
[M::mem_pestat] mean and std.dev: (285.84, 138.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 962)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 210, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 770)
[M::mem_pestat] mean and std.dev: (238.92, 95.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 975)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 689686 reads in 139.179 CPU sec, 4.411 real sec
sorting block 10, #reads = 1086219 mem = 536881983 peak = 905527296
[M::mem_process_seqs] Processed 689454 reads in 90.131 CPU sec, 2.829 real sec
[M::process] read 688852 sequences (100000251 bp) in 1.951 CPU sec, 1.995 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (11, 286659, 2, 20)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (347, 525, 865)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1901)
[M::mem_pestat] mean and std.dev: (536.20, 295.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2419)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 261, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (285.90, 138.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 958)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 269, 714)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1838)
[M::mem_pestat] mean and std.dev: (469.30, 389.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2400)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 11, #reads = 1085266 mem = 536879430 peak = 943230976
[M::process] read 688920 sequences (100000206 bp) in 2.483 CPU sec, 2.615 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (13, 286262, 6, 6)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 427, 830)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2090)
[M::mem_pestat] mean and std.dev: (453.00, 290.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2720)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 261, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (286.37, 138.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 959)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::mem_process_seqs] Processed 689306 reads in 140.916 CPU sec, 4.467 real sec
[M::mem_process_seqs] Processed 688852 reads in 91.623 CPU sec, 2.877 real sec
[M::process] read 688682 sequences (100000251 bp) in 2.015 CPU sec, 2.052 real sec...
sorting block 12, #reads = 1085450 mem = 536879661 peak = 943230976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (13, 286932, 5, 11)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (92, 222, 728)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2000)
[M::mem_pestat] mean and std.dev: (245.82, 180.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2636)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 263, 377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (288.23, 140.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 971)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 210, 613)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1577)
[M::mem_pestat] mean and std.dev: (222.22, 148.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2059)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 688324 sequences (100000074 bp) in 2.264 CPU sec, 2.408 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (8, 286728, 8, 9)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 264, 375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (287.29, 138.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 960)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_process_seqs] Processed 688920 reads in 139.102 CPU sec, 4.411 real sec
[M::mem_process_seqs] Processed 688682 reads in 89.550 CPU sec, 2.816 real sec
[M::process] read 687708 sequences (100000207 bp) in 1.933 CPU sec, 1.965 real sec...
sorting block 13, #reads = 1084502 mem = 536882028 peak = 943230976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (13, 286944, 4, 14)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 337, 3897)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11239)
[M::mem_pestat] mean and std.dev: (1404.54, 2200.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14910)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 265, 377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 769)
[M::mem_pestat] mean and std.dev: (288.64, 138.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 965)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 244, 273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (24, 439)
[M::mem_pestat] mean and std.dev: (228.31, 62.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 522)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 687810 sequences (100000017 bp) in 2.315 CPU sec, 2.424 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (10, 286449, 6, 13)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 415, 712)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1652)
[M::mem_pestat] mean and std.dev: (540.60, 419.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2221)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 267, 378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 770)
[M::mem_pestat] mean and std.dev: (290.43, 139.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 966)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 221, 417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 943)
[M::mem_pestat] mean and std.dev: (276.77, 134.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1206)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 688324 reads in 137.582 CPU sec, 4.374 real sec
[M::mem_process_seqs] Processed 687708 reads in 88.753 CPU sec, 2.789 real sec
sorting block 14, #reads = 1084759 mem = 536881264 peak = 943230976
[M::process] read 687400 sequences (100000083 bp) in 2.129 CPU sec, 2.211 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (15, 286088, 2, 7)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 186, 229)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (85, 325)
[M::mem_pestat] mean and std.dev: (190.29, 40.18)
[M::mem_pestat] low and high boundaries for proper pairs: (30, 373)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 266, 377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 767)
[M::mem_pestat] mean and std.dev: (288.96, 137.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 962)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::process] read 687270 sequences (100000154 bp) in 2.259 CPU sec, 2.364 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (17, 286695, 4, 15)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 178, 2522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7228)
[M::mem_pestat] mean and std.dev: (815.18, 972.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9581)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 268, 379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 771)
[M::mem_pestat] mean and std.dev: (290.96, 138.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 967)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 225, 798)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2026)
[M::mem_pestat] mean and std.dev: (504.27, 521.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2640)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 687810 reads in 139.302 CPU sec, 4.432 real sec
sorting block 15, #reads = 1085194 mem = 536878639 peak = 943230976
[M::mem_process_seqs] Processed 687400 reads in 91.317 CPU sec, 2.874 real sec
[M::process] read 687188 sequences (100000082 bp) in 1.595 CPU sec, 1.641 real sec...
sorting block 16, #reads = 1083209 mem = 536880438 peak = 943230976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 286293, 3, 12)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (313, 348, 405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (129, 589)
[M::mem_pestat] mean and std.dev: (333.79, 53.91)
[M::mem_pestat] low and high boundaries for proper pairs: (37, 681)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 269, 382)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 780)
[M::mem_pestat] mean and std.dev: (292.45, 140.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 979)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 195, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1049)
[M::mem_pestat] mean and std.dev: (219.27, 119.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1345)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 686952 sequences (100000166 bp) in 2.159 CPU sec, 2.280 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 286598, 1, 19)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (122, 239, 287)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 617)
[M::mem_pestat] mean and std.dev: (203.74, 87.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 782)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 271, 384)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 784)
[M::mem_pestat] mean and std.dev: (294.22, 141.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 984)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (282, 451, 2430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6726)
[M::mem_pestat] mean and std.dev: (1125.74, 1257.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8874)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 688750 sequences (100000069 bp) in 1.360 CPU sec, 1.365 real sec...
[M::mem_process_seqs] Processed 687270 reads in 136.851 CPU sec, 4.346 real sec
[M::mem_process_seqs] Processed 687188 reads in 88.789 CPU sec, 2.798 real sec
sorting block 17, #reads = 1083938 mem = 536880747 peak = 943230976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (6, 286206, 4, 9)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 272, 386)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 790)
[M::mem_pestat] mean and std.dev: (295.14, 141.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 992)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::process] read 694112 sequences (100000285 bp) in 2.337 CPU sec, 2.459 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (14, 286643, 9, 13)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 235, 747)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1959)
[M::mem_pestat] mean and std.dev: (360.08, 276.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2565)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 265, 379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 777)
[M::mem_pestat] mean and std.dev: (289.19, 139.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 976)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 251, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 430)
[M::mem_pestat] mean and std.dev: (218.83, 62.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 516)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 686952 reads in 139.097 CPU sec, 4.408 real sec
[M::process] read 693162 sequences (100000097 bp) in 1.862 CPU sec, 1.891 real sec...
[M::mem_process_seqs] Processed 688750 reads in 91.519 CPU sec, 2.872 real sec
sorting block 18, #reads = 1084640 mem = 536880059 peak = 943230976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (16, 288708, 9, 12)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (339, 339, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (283, 423)
[M::mem_pestat] mean and std.dev: (346.00, 11.29)
[M::mem_pestat] low and high boundaries for proper pairs: (255, 451)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 248, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 739)
[M::mem_pestat] mean and std.dev: (273.68, 134.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 929)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 264, 641)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1603)
[M::mem_pestat] mean and std.dev: (318.73, 213.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2084)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 693128 sequences (100000087 bp) in 2.112 CPU sec, 2.223 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (6, 288613, 7, 19)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 251, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (276.98, 136.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 943)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (320, 460, 596)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1148)
[M::mem_pestat] mean and std.dev: (485.84, 258.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1521)
[M::mem_pestat] skip orientation RR
[M::process] read 692700 sequences (100000080 bp) in 1.410 CPU sec, 1.402 real sec...
[M::mem_process_seqs] Processed 694112 reads in 137.366 CPU sec, 4.366 real sec
sorting block 19, #reads = 1084509 mem = 536879210 peak = 943230976
[M::mem_process_seqs] Processed 693162 reads in 89.311 CPU sec, 2.814 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (11, 288375, 4, 10)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 1156, 1381)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3641)
[M::mem_pestat] mean and std.dev: (847.36, 614.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4771)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 252, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 745)
[M::mem_pestat] mean and std.dev: (277.15, 136.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 936)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 204, 215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (29, 339)
[M::mem_pestat] mean and std.dev: (185.78, 34.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 401)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 20, #reads = 1088756 mem = 536879289 peak = 960417792
[M::process] read 692586 sequences (100000136 bp) in 2.692 CPU sec, 2.812 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (16, 288559, 5, 12)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 306, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 604)
[M::mem_pestat] mean and std.dev: (243.20, 77.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 753)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 253, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (277.94, 136.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 944)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 211, 245)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (38, 383)
[M::mem_pestat] mean and std.dev: (203.83, 35.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 452)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 693128 reads in 137.101 CPU sec, 4.346 real sec
[M::mem_process_seqs] Processed 692700 reads in 89.697 CPU sec, 2.819 real sec
[M::process] read 692024 sequences (100000204 bp) in 2.080 CPU sec, 2.147 real sec...
sorting block 21, #reads = 1089257 mem = 536880302 peak = 960417792
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (12, 287798, 9, 18)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (296, 313, 679)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1445)
[M::mem_pestat] mean and std.dev: (441.67, 185.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1828)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 254, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (279.28, 137.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 952)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 295, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701)
[M::mem_pestat] mean and std.dev: (255.62, 129.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 887)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 691624 sequences (100000167 bp) in 2.447 CPU sec, 2.573 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (11, 287998, 3, 4)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 175, 640)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1632)
[M::mem_pestat] mean and std.dev: (276.70, 233.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2128)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 255, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (280.84, 137.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 957)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::mem_process_seqs] Processed 692586 reads in 137.180 CPU sec, 4.351 real sec
[M::mem_process_seqs] Processed 692024 reads in 89.630 CPU sec, 2.818 real sec
[M::process] read 691090 sequences (100000046 bp) in 2.137 CPU sec, 2.199 real sec...
sorting block 22, #reads = 1087778 mem = 536881159 peak = 960417792
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 287908, 2, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 229, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 977)
[M::mem_pestat] mean and std.dev: (287.61, 149.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1232)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 256, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 762)
[M::mem_pestat] mean and std.dev: (281.90, 138.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 958)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (293, 403, 503)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 923)
[M::mem_pestat] mean and std.dev: (360.50, 113.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1133)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 690936 sequences (100000174 bp) in 2.460 CPU sec, 2.590 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (6, 288048, 7, 13)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 259, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 767)
[M::mem_pestat] mean and std.dev: (284.41, 139.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 964)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 279, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (41, 476)
[M::mem_pestat] mean and std.dev: (248.17, 79.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 567)
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 691624 reads in 137.138 CPU sec, 4.358 real sec
sorting block 23, #reads = 1087767 mem = 536883142 peak = 960417792
[M::process] read 690194 sequences (100000211 bp) in 2.209 CPU sec, 2.327 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (10, 287721, 10, 10)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (122, 234, 690)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1826)
[M::mem_pestat] mean and std.dev: (522.50, 616.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2989)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 261, 375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 771)
[M::mem_pestat] mean and std.dev: (286.02, 140.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 969)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 372, 3683)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10631)
[M::mem_pestat] mean and std.dev: (1488.00, 1595.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14105)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (140, 316, 848)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2264)
[M::mem_pestat] mean and std.dev: (493.60, 409.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2972)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 690936 reads in 76.465 CPU sec, 2.405 real sec
[M::process] read 690416 sequences (100000279 bp) in 2.003 CPU sec, 2.047 real sec...
[M::mem_process_seqs] Processed 691090 reads in 197.605 CPU sec, 6.226 real sec
sorting block 24, #reads = 1088339 mem = 536878399 peak = 960417792
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (8, 287411, 10, 11)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 263, 379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 783)
[M::mem_pestat] mean and std.dev: (288.48, 141.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 985)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 1058, 1689)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4667)
[M::mem_pestat] mean and std.dev: (1056.70, 940.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6156)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 204, 898)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2366)
[M::mem_pestat] mean and std.dev: (497.64, 481.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3100)
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690186 sequences (100000065 bp) in 2.566 CPU sec, 2.673 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (16, 287263, 2, 14)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 263, 387)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 721)
[M::mem_pestat] mean and std.dev: (267.86, 109.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 888)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 263, 380)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 786)
[M::mem_pestat] mean and std.dev: (289.09, 142.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 989)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 435, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 889)
[M::mem_pestat] mean and std.dev: (306.23, 126.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1116)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 690194 reads in 152.221 CPU sec, 4.812 real sec
[M::mem_process_seqs] Processed 690416 reads in 91.124 CPU sec, 2.873 real sec
sorting block 25, #reads = 1087387 mem = 536879880 peak = 960417792
[M::process] read 689832 sequences (100000093 bp) in 2.371 CPU sec, 2.513 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (16, 287250, 1, 9)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 348, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 933)
[M::mem_pestat] mean and std.dev: (312.87, 152.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1182)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 262, 379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 783)
[M::mem_pestat] mean and std.dev: (288.28, 141.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 985)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::process] read 689922 sequences (100000219 bp) in 2.195 CPU sec, 2.270 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (11, 287376, 1, 20)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 372, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 922)
[M::mem_pestat] mean and std.dev: (322.09, 131.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1159)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 263, 381)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 787)
[M::mem_pestat] mean and std.dev: (290.01, 143.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 990)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 362, 492)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1054)
[M::mem_pestat] mean and std.dev: (330.28, 132.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1335)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 690186 reads in 140.812 CPU sec, 4.471 real sec
sorting block 26, #reads = 1086991 mem = 536882326 peak = 960417792
[M::mem_process_seqs] Processed 689832 reads in 91.490 CPU sec, 2.877 real sec
[M::process] read 689628 sequences (100000085 bp) in 1.905 CPU sec, 2.006 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (16, 287650, 9, 14)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 278, 503)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1201)
[M::mem_pestat] mean and std.dev: (274.43, 148.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1550)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 262, 380)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 784)
[M::mem_pestat] mean and std.dev: (288.61, 141.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 986)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 799, 799)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1905)
[M::mem_pestat] mean and std.dev: (527.64, 283.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2458)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 27, #reads = 1086127 mem = 536877787 peak = 965836800
[M::process] read 689684 sequences (100000067 bp) in 2.462 CPU sec, 2.584 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (13, 287160, 5, 11)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 169, 248)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 468)
[M::mem_pestat] mean and std.dev: (162.42, 62.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 578)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 262, 377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 775)
[M::mem_pestat] mean and std.dev: (287.81, 140.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 974)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 244, 399)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 731)
[M::mem_pestat] mean and std.dev: (295.27, 84.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 897)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 689922 reads in 139.831 CPU sec, 4.440 real sec
[M::mem_process_seqs] Processed 689628 reads in 91.581 CPU sec, 2.878 real sec
[M::process] read 689840 sequences (100000127 bp) in 2.141 CPU sec, 2.241 real sec...
sorting block 28, #reads = 1086740 mem = 536879686 peak = 965836800
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (6, 286725, 4, 18)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 261, 375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 769)
[M::mem_pestat] mean and std.dev: (286.95, 140.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 966)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 278, 417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 917)
[M::mem_pestat] mean and std.dev: (274.61, 117.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1167)
[M::mem_pestat] skip orientation RR
[M::process] read 689924 sequences (100000110 bp) in 2.108 CPU sec, 2.215 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (9, 287440, 5, 12)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 259, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 759)
[M::mem_pestat] mean and std.dev: (284.15, 137.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 953)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 315, 503)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1125)
[M::mem_pestat] mean and std.dev: (295.80, 150.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1436)
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 689684 reads in 140.779 CPU sec, 4.473 real sec
[M::mem_process_seqs] Processed 689840 reads in 92.018 CPU sec, 2.900 real sec
[M::process] read 690002 sequences (100000228 bp) in 1.854 CPU sec, 1.919 real sec...
sorting block 29, #reads = 1085022 mem = 536879854 peak = 965836800
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 286801, 4, 13)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 363, 1362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3684)
[M::mem_pestat] mean and std.dev: (731.95, 793.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4845)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 258, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (282.92, 136.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 945)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 188, 415)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 881)
[M::mem_pestat] mean and std.dev: (283.00, 173.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1114)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 689690 sequences (100000223 bp) in 2.083 CPU sec, 2.195 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (12, 287150, 2, 5)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (126, 192, 400)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 948)
[M::mem_pestat] mean and std.dev: (219.36, 121.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1222)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 259, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (283.27, 137.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::process] read 689408 sequences (100000002 bp) in 1.320 CPU sec, 1.324 real sec...
[M::mem_process_seqs] Processed 689924 reads in 139.613 CPU sec, 4.438 real sec
[M::mem_process_seqs] Processed 690002 reads in 89.417 CPU sec, 2.827 real sec
sorting block 30, #reads = 1085583 mem = 536878210 peak = 965836800
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (10, 286920, 5, 7)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 316, 2195)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6143)
[M::mem_pestat] mean and std.dev: (1244.40, 1525.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8117)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 259, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 759)
[M::mem_pestat] mean and std.dev: (283.67, 136.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 953)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::process] read 688970 sequences (100000101 bp) in 2.272 CPU sec, 2.389 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (11, 286958, 3, 12)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 779, 1229)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3317)
[M::mem_pestat] mean and std.dev: (861.55, 829.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4361)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 261, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (285.63, 137.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 955)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 614, 882)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2300)
[M::mem_pestat] mean and std.dev: (500.50, 305.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3009)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 689690 reads in 139.178 CPU sec, 4.418 real sec
sorting block 31, #reads = 1084918 mem = 536879768 peak = 990908416
[M::mem_process_seqs] Processed 689408 reads in 90.096 CPU sec, 2.828 real sec
[M::process] read 689198 sequences (100000154 bp) in 1.854 CPU sec, 1.898 real sec...
sorting block 32, #reads = 1084483 mem = 536880333 peak = 1085095936
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 286849, 4, 10)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 330, 380)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 772)
[M::mem_pestat] mean and std.dev: (295.61, 138.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 968)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 261, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (285.09, 137.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 951)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 279, 830)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2156)
[M::mem_pestat] mean and std.dev: (495.40, 486.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2819)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 688960 sequences (100000024 bp) in 2.356 CPU sec, 2.468 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 286644, 7, 13)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 241, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653)
[M::mem_pestat] mean and std.dev: (252.47, 71.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 801)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 261, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (284.92, 136.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 951)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 210, 287)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 509)
[M::mem_pestat] mean and std.dev: (194.18, 64.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 620)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 688970 reads in 140.621 CPU sec, 4.460 real sec
[M::mem_process_seqs] Processed 689198 reads in 90.831 CPU sec, 2.852 real sec
[M::process] read 688656 sequences (100000014 bp) in 1.901 CPU sec, 1.915 real sec...
sorting block 33, #reads = 1086012 mem = 536878329 peak = 1085095936
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (15, 286657, 2, 9)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 284, 284)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 482)
[M::mem_pestat] mean and std.dev: (254.73, 119.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 733)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 262, 375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 767)
[M::mem_pestat] mean and std.dev: (286.57, 138.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 963)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::process] read 688594 sequences (100000199 bp) in 2.311 CPU sec, 2.430 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 286722, 2, 20)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 243, 628)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1398)
[M::mem_pestat] mean and std.dev: (261.47, 121.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1783)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 264, 378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 774)
[M::mem_pestat] mean and std.dev: (289.19, 140.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 972)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 365, 776)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1880)
[M::mem_pestat] mean and std.dev: (482.95, 381.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2432)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 688960 reads in 138.683 CPU sec, 4.410 real sec
[M::mem_process_seqs] Processed 688656 reads in 90.961 CPU sec, 2.858 real sec
[M::process] read 688286 sequences (100000163 bp) in 2.059 CPU sec, 2.122 real sec...
sorting block 34, #reads = 1084481 mem = 536879445 peak = 1085095936
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (6, 287295, 12, 12)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 265, 378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 774)
[M::mem_pestat] mean and std.dev: (289.28, 140.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 972)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (85, 214, 2623)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7699)
[M::mem_pestat] mean and std.dev: (822.42, 1057.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10237)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 1603, 1901)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5253)
[M::mem_pestat] mean and std.dev: (1114.67, 784.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6929)
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 688286 sequences (100000089 bp) in 2.419 CPU sec, 2.534 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (11, 286467, 7, 10)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 232, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (147, 332)
[M::mem_pestat] mean and std.dev: (220.62, 41.23)
[M::mem_pestat] low and high boundaries for proper pairs: (56, 386)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 266, 379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 775)
[M::mem_pestat] mean and std.dev: (289.93, 139.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 973)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 306, 382)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 686)
[M::mem_pestat] mean and std.dev: (266.89, 93.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 838)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 688594 reads in 137.902 CPU sec, 4.377 real sec
sorting block 35, #reads = 1084995 mem = 536877663 peak = 1085095936
[M::process] read 688308 sequences (100000280 bp) in 1.945 CPU sec, 2.013 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (13, 287062, 4, 14)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 400, 3548)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10362)
[M::mem_pestat] mean and std.dev: (1169.77, 1378.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13769)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 265, 378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 772)
[M::mem_pestat] mean and std.dev: (289.13, 139.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 969)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 1581, 1685)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4609)
[M::mem_pestat] mean and std.dev: (1078.43, 820.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6071)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 688286 reads in 78.085 CPU sec, 2.465 real sec
[M::process] read 688574 sequences (100000011 bp) in 1.800 CPU sec, 1.816 real sec...
[M::mem_process_seqs] Processed 688286 reads in 193.861 CPU sec, 6.120 real sec
sorting block 36, #reads = 1085777 mem = 536879944 peak = 1085095936
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (11, 287024, 3, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 215, 1185)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3231)
[M::mem_pestat] mean and std.dev: (676.82, 847.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4254)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 266, 383)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 787)
[M::mem_pestat] mean and std.dev: (292.16, 142.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 989)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 1154, 1734)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4732)
[M::mem_pestat] mean and std.dev: (954.33, 730.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6231)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 692556 sequences (100000127 bp) in 2.608 CPU sec, 2.730 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (6, 287216, 3, 10)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 264, 382)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 786)
[M::mem_pestat] mean and std.dev: (290.84, 142.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 988)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 335, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 719)
[M::mem_pestat] mean and std.dev: (257.50, 80.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 902)
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 688308 reads in 153.903 CPU sec, 4.882 real sec
[M::mem_process_seqs] Processed 688574 reads in 92.833 CPU sec, 2.937 real sec
sorting block 37, #reads = 1083054 mem = 536884293 peak = 1085095936
[M::process] read 694830 sequences (100000032 bp) in 2.065 CPU sec, 2.187 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (15, 288158, 14, 10)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 274, 609)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1417)
[M::mem_pestat] mean and std.dev: (413.73, 332.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1821)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 254, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (279.62, 137.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (360, 1764, 4735)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13485)
[M::mem_pestat] mean and std.dev: (2575.64, 2239.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17860)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 389, 959)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2479)
[M::mem_pestat] mean and std.dev: (441.38, 305.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3239)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694124 sequences (100000296 bp) in 2.241 CPU sec, 2.414 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (9, 289188, 8, 5)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 247, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 738)
[M::mem_pestat] mean and std.dev: (272.80, 134.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 928)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_process_seqs] Processed 692556 reads in 154.758 CPU sec, 4.964 real sec
sorting block 38, #reads = 1083778 mem = 536878581 peak = 1085095936
[M::process] read 694314 sequences (100000245 bp) in 1.660 CPU sec, 1.692 real sec...
[M::mem_process_seqs] Processed 694830 reads in 103.620 CPU sec, 3.303 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (14, 288587, 13, 11)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 179, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 673)
[M::mem_pestat] mean and std.dev: (208.31, 78.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 849)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 249, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 742)
[M::mem_pestat] mean and std.dev: (274.01, 134.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 933)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (62, 341, 801)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2279)
[M::mem_pestat] mean and std.dev: (355.85, 292.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3018)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 412, 2641)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7523)
[M::mem_pestat] mean and std.dev: (1336.45, 1226.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9964)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 39, #reads = 1088114 mem = 536877397 peak = 1138466816
[M::process] read 693418 sequences (100000046 bp) in 2.587 CPU sec, 2.777 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (10, 288586, 5, 11)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 236, 236)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (14, 384)
[M::mem_pestat] mean and std.dev: (211.30, 60.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 458)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 248, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 739)
[M::mem_pestat] mean and std.dev: (273.28, 133.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 929)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 266, 267)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (36, 421)
[M::mem_pestat] mean and std.dev: (211.89, 65.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 498)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694124 reads in 150.455 CPU sec, 4.826 real sec
[M::mem_process_seqs] Processed 694314 reads in 98.033 CPU sec, 3.089 real sec
[M::process] read 692722 sequences (100000104 bp) in 2.106 CPU sec, 2.198 real sec...
sorting block 40, #reads = 1088493 mem = 536880197 peak = 1138466816
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (10, 288454, 5, 5)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 730, 764)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1940)
[M::mem_pestat] mean and std.dev: (434.89, 287.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2528)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 251, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 744)
[M::mem_pestat] mean and std.dev: (275.95, 134.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 935)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::process] read 692190 sequences (100000291 bp) in 2.297 CPU sec, 2.410 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (8, 288147, 4, 16)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 254, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (277.98, 135.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 944)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 408, 1432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3816)
[M::mem_pestat] mean and std.dev: (639.56, 534.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5008)
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 693418 reads in 142.286 CPU sec, 4.517 real sec
[M::mem_process_seqs] Processed 692722 reads in 91.378 CPU sec, 2.870 real sec
[M::process] read 691382 sequences (100000208 bp) in 1.903 CPU sec, 1.938 real sec...
sorting block 41, #reads = 1088926 mem = 536877667 peak = 1138466816
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (11, 287879, 5, 14)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (364, 481, 783)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1621)
[M::mem_pestat] mean and std.dev: (541.90, 286.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2040)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 255, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 749)
[M::mem_pestat] mean and std.dev: (278.82, 135.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 941)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (126, 725, 907)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2469)
[M::mem_pestat] mean and std.dev: (500.08, 345.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3250)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 691104 sequences (100000172 bp) in 2.562 CPU sec, 2.701 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (7, 287571, 4, 9)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 259, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (282.73, 136.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 956)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_process_seqs] Processed 692190 reads in 140.683 CPU sec, 4.473 real sec
[M::mem_process_seqs] Processed 691382 reads in 91.779 CPU sec, 2.888 real sec
sorting block 42, #reads = 1086951 mem = 536877961 peak = 1138466816
[M::process] read 690850 sequences (100000091 bp) in 1.993 CPU sec, 2.065 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (8, 287833, 9, 14)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 260, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (283.96, 137.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 960)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 290, 1181)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3109)
[M::mem_pestat] mean and std.dev: (504.23, 423.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4073)
[M::mem_pestat] skip orientation RR
sorting block 43, #reads = 1086204 mem = 536879449 peak = 1138466816
[M::process] read 690570 sequences (100000168 bp) in 2.450 CPU sec, 2.545 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (10, 287874, 8, 14)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 253, 809)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2131)
[M::mem_pestat] mean and std.dev: (458.20, 420.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2792)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 260, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (283.53, 136.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 960)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 276, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 583)
[M::mem_pestat] mean and std.dev: (250.21, 67.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 718)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 691104 reads in 139.407 CPU sec, 4.429 real sec
[M::mem_process_seqs] Processed 690850 reads in 90.963 CPU sec, 2.860 real sec
[M::process] read 690294 sequences (100000088 bp) in 1.703 CPU sec, 1.742 real sec...
sorting block 44, #reads = 1086195 mem = 536880599 peak = 1138466816
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (7, 287450, 13, 9)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 262, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (285.05, 137.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 961)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (316, 316, 1614)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4210)
[M::mem_pestat] mean and std.dev: (607.77, 571.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5508)
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation RF
[M::process] read 690268 sequences (100000287 bp) in 2.453 CPU sec, 2.571 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (14, 287288, 8, 10)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 260, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (36, 471)
[M::mem_pestat] mean and std.dev: (216.82, 52.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 558)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 262, 375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 771)
[M::mem_pestat] mean and std.dev: (286.00, 138.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 969)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 181, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 524)
[M::mem_pestat] mean and std.dev: (198.11, 108.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 656)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 690570 reads in 138.403 CPU sec, 4.393 real sec
[M::mem_process_seqs] Processed 690294 reads in 90.929 CPU sec, 2.856 real sec
[M::process] read 690004 sequences (100000030 bp) in 1.999 CPU sec, 2.057 real sec...
sorting block 45, #reads = 1086330 mem = 536878606 peak = 1138466816
[M::process] read 689418 sequences (100000168 bp) in 2.448 CPU sec, 2.715 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (9, 287607, 4, 15)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 263, 376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 772)
[M::mem_pestat] mean and std.dev: (286.96, 139.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 970)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 279, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 676)
[M::mem_pestat] mean and std.dev: (261.31, 78.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 690004 reads in 84.922 CPU sec, 2.793 real sec
[M::process] read 690150 sequences (100000215 bp) in 1.861 CPU sec, 1.987 real sec...
sorting block 46, #reads = 1085494 mem = 536880150 peak = 1138466816
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (14, 287342, 2, 10)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (370, 392, 834)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1762)
[M::mem_pestat] mean and std.dev: (509.50, 265.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2226)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 261, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (285.08, 137.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 961)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 807, 2908)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8226)
[M::mem_pestat] mean and std.dev: (1363.10, 1273.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10885)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (14, 287351, 4, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 208, 652)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1654)
[M::mem_pestat] mean and std.dev: (374.00, 289.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2155)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 265, 378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 776)
[M::mem_pestat] mean and std.dev: (288.33, 139.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 975)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 161, 378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 820)
[M::mem_pestat] mean and std.dev: (239.38, 105.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1041)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 690268 reads in 230.725 CPU sec, 7.579 real sec
[M::mem_process_seqs] Processed 689418 reads in 116.318 CPU sec, 3.899 real sec
[M::process] read 689920 sequences (100000194 bp) in 2.157 CPU sec, 2.267 real sec...
sorting block 47, #reads = 1086935 mem = 536880635 peak = 1138466816
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (11, 287569, 2, 20)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 231, 618)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1568)
[M::mem_pestat] mean and std.dev: (317.73, 228.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2043)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 260, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (284.76, 138.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 961)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 296, 733)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1725)
[M::mem_pestat] mean and std.dev: (423.30, 312.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2221)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 689338 sequences (100000245 bp) in 2.272 CPU sec, 2.840 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (5, 287363, 10, 12)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 259, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (283.49, 136.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (48, 551, 1499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4401)
[M::mem_pestat] mean and std.dev: (1066.30, 1221.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5951)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (113, 341, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 797)
[M::mem_pestat] mean and std.dev: (213.40, 105.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1025)
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 690150 reads in 152.261 CPU sec, 5.022 real sec
[M::process] read 689276 sequences (100000286 bp) in 2.001 CPU sec, 2.148 real sec...
sorting block 48, #reads = 1086562 mem = 536878646 peak = 1138466816
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (9, 287244, 5, 9)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 261, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (285.65, 137.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 958)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_process_seqs] Processed 689338 reads in 86.691 CPU sec, 2.831 real sec
[M::process] read 689308 sequences (100000203 bp) in 1.597 CPU sec, 1.794 real sec...
[M::mem_process_seqs] Processed 689920 reads in 232.304 CPU sec, 7.647 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (17, 286991, 2, 17)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 863, 1310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3614)
[M::mem_pestat] mean and std.dev: (729.47, 537.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4766)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 260, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (284.70, 136.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 951)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 176, 639)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1663)
[M::mem_pestat] mean and std.dev: (236.33, 165.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2175)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 49, #reads = 1085680 mem = 536878970 peak = 1138466816
[M::process] read 689458 sequences (100000026 bp) in 2.488 CPU sec, 2.871 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (14, 287175, 8, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 236, 271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 475)
[M::mem_pestat] mean and std.dev: (222.54, 89.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 582)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 261, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (285.14, 137.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 271, 820)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2088)
[M::mem_pestat] mean and std.dev: (345.05, 256.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2722)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 689276 reads in 171.712 CPU sec, 5.675 real sec
[M::mem_process_seqs] Processed 689308 reads in 103.418 CPU sec, 3.423 real sec
[M::process] read 688926 sequences (100000003 bp) in 2.165 CPU sec, 2.312 real sec...
sorting block 50, #reads = 1085380 mem = 536881371 peak = 1138466816
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (13, 286918, 10, 18)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 620, 1248)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3380)
[M::mem_pestat] mean and std.dev: (668.62, 518.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4446)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 261, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (285.04, 137.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (627, 1120, 1464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3138)
[M::mem_pestat] mean and std.dev: (853.78, 463.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3975)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 262, 1165)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3135)
[M::mem_pestat] mean and std.dev: (432.19, 417.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4120)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 689112 sequences (100000160 bp) in 2.109 CPU sec, 2.564 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (12, 287180, 13, 16)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 280, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 621)
[M::mem_pestat] mean and std.dev: (253.33, 90.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 761)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 262, 375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 767)
[M::mem_pestat] mean and std.dev: (286.98, 138.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 963)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (516, 559, 605)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (338, 783)
[M::mem_pestat] mean and std.dev: (559.90, 34.48)
[M::mem_pestat] low and high boundaries for proper pairs: (249, 872)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 424, 845)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2107)
[M::mem_pestat] mean and std.dev: (421.50, 281.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2738)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 689458 reads in 154.378 CPU sec, 5.129 real sec
[M::mem_process_seqs] Processed 688926 reads in 102.001 CPU sec, 3.382 real sec
[M::process] read 688986 sequences (100000047 bp) in 1.689 CPU sec, 1.753 real sec...
sorting block 51, #reads = 1084368 mem = 536877523 peak = 1138466816
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (12, 286791, 2, 7)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (330, 738, 863)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1929)
[M::mem_pestat] mean and std.dev: (585.45, 306.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2462)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 261, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 749)
[M::mem_pestat] mean and std.dev: (283.93, 135.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 939)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::process] read 688900 sequences (100000057 bp) in 2.505 CPU sec, 3.080 real sec...
sorting block 52, #reads = 1083799 mem = 536880558 peak = 1138466816
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (16, 287049, 10, 14)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 269, 1276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3332)
[M::mem_pestat] mean and std.dev: (331.92, 303.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4360)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 262, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (286.07, 137.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 955)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 328, 671)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1643)
[M::mem_pestat] mean and std.dev: (443.33, 435.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2185)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 838, 921)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2281)
[M::mem_pestat] mean and std.dev: (643.07, 366.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2961)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 689112 reads in 154.032 CPU sec, 5.146 real sec
[M::process] read 689194 sequences (100000280 bp) in 1.900 CPU sec, 2.023 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (15, 286663, 6, 4)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 509, 817)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1969)
[M::mem_pestat] mean and std.dev: (432.86, 254.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2545)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 263, 375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (287.12, 138.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 960)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::mem_process_seqs] Processed 688900 reads in 84.374 CPU sec, 2.772 real sec
[M::process] read 688652 sequences (100000093 bp) in 2.212 CPU sec, 2.492 real sec...
sorting block 53, #reads = 1083877 mem = 536881603 peak = 1138466816
[M::mem_process_seqs] Processed 688986 reads in 232.936 CPU sec, 7.720 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 286948, 5, 7)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 305, 650)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1464)
[M::mem_pestat] mean and std.dev: (326.41, 179.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1871)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 263, 376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 770)
[M::mem_pestat] mean and std.dev: (287.67, 139.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 967)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::process] read 688964 sequences (100000155 bp) in 2.277 CPU sec, 2.582 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (15, 286613, 6, 9)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (434, 577, 3774)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10454)
[M::mem_pestat] mean and std.dev: (1614.67, 1558.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13794)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 263, 377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (288.51, 140.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 971)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::mem_process_seqs] Processed 689194 reads in 174.174 CPU sec, 5.722 real sec
sorting block 54, #reads = 1083830 mem = 536881915 peak = 1138466816
[M::mem_process_seqs] Processed 688652 reads in 106.384 CPU sec, 3.491 real sec
[M::process] read 688720 sequences (100000052 bp) in 1.948 CPU sec, 2.237 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (13, 286762, 17, 13)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 292, 740)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1850)
[M::mem_pestat] mean and std.dev: (425.46, 270.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2405)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 263, 377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (288.03, 140.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 971)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (98, 217, 1243)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3533)
[M::mem_pestat] mean and std.dev: (574.50, 680.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4678)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 187, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 508)
[M::mem_pestat] mean and std.dev: (213.67, 71.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 625)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 55, #reads = 1082543 mem = 536881054 peak = 1152061440
[M::process] read 689024 sequences (100000143 bp) in 2.112 CPU sec, 2.357 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (8, 286917, 9, 13)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 263, 378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 776)
[M::mem_pestat] mean and std.dev: (288.44, 140.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 975)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 185, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 759)
[M::mem_pestat] mean and std.dev: (210.92, 80.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 958)
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 688964 reads in 154.701 CPU sec, 5.256 real sec
[M::mem_process_seqs] Processed 688720 reads in 103.954 CPU sec, 3.597 real sec
[M::process] read 692364 sequences (100000186 bp) in 1.974 CPU sec, 2.124 real sec...
sorting block 56, #reads = 1083460 mem = 536878327 peak = 1152061440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (13, 286698, 9, 12)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 251, 308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 556)
[M::mem_pestat] mean and std.dev: (216.64, 61.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 680)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 261, 376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 770)
[M::mem_pestat] mean and std.dev: (287.19, 139.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 967)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 235, 1515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4285)
[M::mem_pestat] mean and std.dev: (936.00, 1066.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5670)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 693824 sequences (100000244 bp) in 2.436 CPU sec, 3.007 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (8, 287901, 14, 9)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 253, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 745)
[M::mem_pestat] mean and std.dev: (277.54, 135.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 936)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (43, 53, 113)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 253)
[M::mem_pestat] mean and std.dev: (49.82, 32.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 323)
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation RF
[M::mem_process_seqs] Processed 689024 reads in 157.644 CPU sec, 5.179 real sec
[M::mem_process_seqs] Processed 692364 reads in 107.295 CPU sec, 3.496 real sec
[M::process] read 693522 sequences (100000005 bp) in 1.803 CPU sec, 1.833 real sec...
sorting block 57, #reads = 1083428 mem = 536879027 peak = 1152061440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (6, 288423, 4, 14)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 250, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 740)
[M::mem_pestat] mean and std.dev: (274.75, 134.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 930)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 233, 277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 529)
[M::mem_pestat] mean and std.dev: (218.79, 81.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 655)
[M::mem_pestat] skip orientation RR
[M::process] read 693202 sequences (100000176 bp) in 2.433 CPU sec, 2.776 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (13, 288201, 3, 14)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (132, 166, 691)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1809)
[M::mem_pestat] mean and std.dev: (385.92, 407.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2368)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 251, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 744)
[M::mem_pestat] mean and std.dev: (275.99, 135.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 935)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 354, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (280.92, 137.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 942)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 693824 reads in 147.596 CPU sec, 4.930 real sec
[M::mem_process_seqs] Processed 693522 reads in 98.489 CPU sec, 3.237 real sec
sorting block 58, #reads = 1084928 mem = 536880853 peak = 1152061440
[M::process] read 692964 sequences (100000139 bp) in 1.981 CPU sec, 2.191 real sec...
sorting block 59, #reads = 1088810 mem = 536877939 peak = 1152061440
[M::process] read 692374 sequences (100000191 bp) in 2.387 CPU sec, 2.763 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (13, 288082, 6, 9)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 387, 3603)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10367)
[M::mem_pestat] mean and std.dev: (1281.23, 1375.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13749)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 253, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (277.73, 135.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 940)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::mem_process_seqs] Processed 692964 reads in 86.480 CPU sec, 2.826 real sec
[M::process] read 692086 sequences (100000073 bp) in 1.869 CPU sec, 1.929 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 288390, 7, 13)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 260, 581)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1421)
[M::mem_pestat] mean and std.dev: (292.44, 242.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1841)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 252, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (277.49, 135.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 940)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 241, 406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 892)
[M::mem_pestat] mean and std.dev: (239.75, 93.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1135)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (2, 287787, 6, 12)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 255, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (279.99, 136.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 232, 407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 885)
[M::mem_pestat] mean and std.dev: (227.90, 95.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1124)
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 693202 reads in 232.178 CPU sec, 7.570 real sec
[M::process] read 691582 sequences (100000090 bp) in 1.673 CPU sec, 1.687 real sec...
[M::mem_process_seqs] Processed 692374 reads in 111.385 CPU sec, 3.594 real sec
sorting block 60, #reads = 1087837 mem = 536879909 peak = 1152061440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (18, 288289, 6, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (128, 448, 897)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2435)
[M::mem_pestat] mean and std.dev: (516.29, 388.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3204)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 257, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 759)
[M::mem_pestat] mean and std.dev: (281.25, 137.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 324, 533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1261)
[M::mem_pestat] mean and std.dev: (286.74, 128.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1625)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 691144 sequences (100000226 bp) in 2.095 CPU sec, 2.230 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (9, 287539, 2, 10)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 258, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (282.29, 137.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 962)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 286, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 656)
[M::mem_pestat] mean and std.dev: (283.00, 98.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 802)
[M::mem_pestat] skip orientation RR
[M::process] read 690952 sequences (100000232 bp) in 1.360 CPU sec, 1.361 real sec...
[M::mem_process_seqs] Processed 692086 reads in 138.660 CPU sec, 4.409 real sec
sorting block 61, #reads = 1087631 mem = 536882391 peak = 1152061440
[M::mem_process_seqs] Processed 691582 reads in 89.819 CPU sec, 2.848 real sec
sorting block 62, #reads = 1087430 mem = 536879155 peak = 1153376256
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (10, 287806, 2, 13)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (115, 174, 917)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2521)
[M::mem_pestat] mean and std.dev: (390.30, 384.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3323)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 260, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 767)
[M::mem_pestat] mean and std.dev: (284.48, 138.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 964)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 291, 975)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2497)
[M::mem_pestat] mean and std.dev: (501.92, 336.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3258)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 690774 sequences (100000257 bp) in 2.090 CPU sec, 2.225 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 287040, 8, 15)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 276, 621)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1491)
[M::mem_pestat] mean and std.dev: (299.00, 184.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1926)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 260, 375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (285.34, 139.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 972)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (648, 889, 1054)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1866)
[M::mem_pestat] mean and std.dev: (736.62, 287.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2272)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 690212 sequences (100000217 bp) in 1.452 CPU sec, 1.456 real sec...
[M::mem_process_seqs] Processed 691144 reads in 141.681 CPU sec, 4.502 real sec
[M::mem_process_seqs] Processed 690952 reads in 93.433 CPU sec, 2.951 real sec
sorting block 63, #reads = 1086934 mem = 536878724 peak = 1153376256
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 287355, 4, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 338, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (20, 595)
[M::mem_pestat] mean and std.dev: (273.47, 71.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 710)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 261, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 768)
[M::mem_pestat] mean and std.dev: (284.62, 137.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 965)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 204, 294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 536)
[M::mem_pestat] mean and std.dev: (210.27, 71.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 657)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 690300 sequences (100000236 bp) in 2.536 CPU sec, 2.649 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (10, 287089, 7, 11)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 227, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 570)
[M::mem_pestat] mean and std.dev: (306.00, 113.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 758)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 262, 376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 772)
[M::mem_pestat] mean and std.dev: (286.33, 138.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 970)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 150, 263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 489)
[M::mem_pestat] mean and std.dev: (164.22, 36.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 602)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 689978 sequences (100000126 bp) in 1.780 CPU sec, 1.780 real sec...
[M::mem_process_seqs] Processed 690774 reads in 150.094 CPU sec, 4.753 real sec
[M::mem_process_seqs] Processed 690212 reads in 98.969 CPU sec, 3.125 real sec
sorting block 64, #reads = 1086290 mem = 536878392 peak = 1153376256
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 287120, 5, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 329, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 675)
[M::mem_pestat] mean and std.dev: (239.16, 103.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 846)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 262, 375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 769)
[M::mem_pestat] mean and std.dev: (286.01, 138.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 966)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 244, 263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (206, 301)
[M::mem_pestat] mean and std.dev: (245.32, 12.45)
[M::mem_pestat] low and high boundaries for proper pairs: (187, 320)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 690284 sequences (100000092 bp) in 2.169 CPU sec, 2.407 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (8, 287018, 5, 9)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 263, 376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 772)
[M::mem_pestat] mean and std.dev: (286.95, 138.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 970)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::process] read 691070 sequences (100000290 bp) in 1.614 CPU sec, 1.623 real sec...
[M::mem_process_seqs] Processed 690300 reads in 155.698 CPU sec, 4.988 real sec
sorting block 65, #reads = 1085575 mem = 536878367 peak = 1153376256
[M::mem_process_seqs] Processed 689978 reads in 103.017 CPU sec, 3.274 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (16, 287171, 16, 4)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (325, 485, 1902)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5056)
[M::mem_pestat] mean and std.dev: (824.38, 739.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6633)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 263, 378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 778)
[M::mem_pestat] mean and std.dev: (287.85, 140.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 978)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (9, 65, 98)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 276)
[M::mem_pestat] mean and std.dev: (40.77, 37.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 365)
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
sorting block 66, #reads = 1085271 mem = 536877046 peak = 1153376256
[M::process] read 691954 sequences (100000132 bp) in 2.636 CPU sec, 2.828 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (11, 287871, 10, 16)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (129, 136, 193)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 321)
[M::mem_pestat] mean and std.dev: (159.20, 50.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 385)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 258, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (283.70, 138.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 960)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (66, 172, 528)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1452)
[M::mem_pestat] mean and std.dev: (227.22, 178.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1914)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 260, 1356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3668)
[M::mem_pestat] mean and std.dev: (606.81, 567.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4824)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 690284 reads in 155.661 CPU sec, 4.993 real sec
[M::process] read 690442 sequences (100000111 bp) in 1.800 CPU sec, 1.815 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (15, 288129, 9, 17)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 273, 913)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2295)
[M::mem_pestat] mean and std.dev: (476.40, 373.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2986)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 250, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 731)
[M::mem_pestat] mean and std.dev: (275.61, 133.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 917)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 246, 610)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1460)
[M::mem_pestat] mean and std.dev: (363.18, 257.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1885)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 690358 sequences (100000061 bp) in 1.909 CPU sec, 1.914 real sec...
[M::mem_process_seqs] Processed 691954 reads in 87.986 CPU sec, 2.792 real sec
sorting block 67, #reads = 1085695 mem = 536878189 peak = 1153376256
[M::mem_process_seqs] Processed 691070 reads in 221.603 CPU sec, 7.069 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 286973, 4, 13)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 308, 429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 901)
[M::mem_pestat] mean and std.dev: (271.23, 108.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1137)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 258, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (282.42, 136.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 948)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 223, 673)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1713)
[M::mem_pestat] mean and std.dev: (342.85, 257.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2233)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 68, #reads = 1085905 mem = 536878090 peak = 1153376256
[M::process] read 689870 sequences (100000260 bp) in 2.588 CPU sec, 2.837 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (16, 287209, 6, 16)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (117, 205, 617)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1617)
[M::mem_pestat] mean and std.dev: (345.00, 269.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2117)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 256, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 746)
[M::mem_pestat] mean and std.dev: (280.68, 134.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 936)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 445, 668)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1634)
[M::mem_pestat] mean and std.dev: (430.07, 238.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2117)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 690442 reads in 175.555 CPU sec, 5.632 real sec
[M::mem_process_seqs] Processed 690358 reads in 106.018 CPU sec, 3.401 real sec
[M::process] read 689366 sequences (100000238 bp) in 1.707 CPU sec, 1.808 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (14, 287347, 8, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 270, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 788)
[M::mem_pestat] mean and std.dev: (265.00, 117.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1000)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 258, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 747)
[M::mem_pestat] mean and std.dev: (281.96, 135.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 937)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 183, 253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 461)
[M::mem_pestat] mean and std.dev: (174.05, 61.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 565)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 69, #reads = 1086335 mem = 536880675 peak = 1153376256
[M::process] read 689714 sequences (100000086 bp) in 2.287 CPU sec, 2.509 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (15, 286612, 4, 18)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 229, 285)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 481)
[M::mem_pestat] mean and std.dev: (224.38, 53.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 579)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 259, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (282.32, 134.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 938)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 294, 294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 492)
[M::mem_pestat] mean and std.dev: (250.00, 82.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 591)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 689870 reads in 155.684 CPU sec, 5.003 real sec
[M::process] read 689484 sequences (100000061 bp) in 1.689 CPU sec, 1.707 real sec...
[M::mem_process_seqs] Processed 689366 reads in 103.849 CPU sec, 3.313 real sec
sorting block 70, #reads = 1084520 mem = 536880281 peak = 1153376256
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (14, 286996, 6, 13)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 397, 398)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 724)
[M::mem_pestat] mean and std.dev: (289.75, 137.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 887)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 259, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 745)
[M::mem_pestat] mean and std.dev: (281.80, 134.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 934)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 278, 1525)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4273)
[M::mem_pestat] mean and std.dev: (633.77, 631.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5647)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 689058 sequences (100000115 bp) in 2.194 CPU sec, 2.433 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (6, 286685, 4, 18)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 259, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 745)
[M::mem_pestat] mean and std.dev: (281.96, 134.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 934)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (258, 411, 1077)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2715)
[M::mem_pestat] mean and std.dev: (555.17, 360.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3534)
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 689714 reads in 156.955 CPU sec, 5.061 real sec
[M::mem_process_seqs] Processed 689484 reads in 103.835 CPU sec, 3.328 real sec
[M::process] read 689310 sequences (100000025 bp) in 1.797 CPU sec, 1.889 real sec...
sorting block 71, #reads = 1083827 mem = 536878291 peak = 1153376256
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (10, 287056, 12, 14)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (129, 191, 683)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1791)
[M::mem_pestat] mean and std.dev: (346.00, 264.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2345)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 259, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 740)
[M::mem_pestat] mean and std.dev: (281.50, 132.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 927)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 598, 3213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9109)
[M::mem_pestat] mean and std.dev: (1412.25, 1328.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12057)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 498, 698)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1680)
[M::mem_pestat] mean and std.dev: (469.92, 391.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2171)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 689008 sequences (100000275 bp) in 2.361 CPU sec, 2.641 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (7, 287289, 4, 8)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 259, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 742)
[M::mem_pestat] mean and std.dev: (281.36, 133.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 930)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_process_seqs] Processed 689058 reads in 157.633 CPU sec, 5.113 real sec
[M::mem_process_seqs] Processed 689310 reads in 104.717 CPU sec, 3.360 real sec
sorting block 72, #reads = 1083480 mem = 536882443 peak = 1153376256
[M::process] read 688766 sequences (100000253 bp) in 1.930 CPU sec, 2.008 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (16, 286652, 3, 7)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 663, 663)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1651)
[M::mem_pestat] mean and std.dev: (509.94, 393.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2145)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 261, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 752)
[M::mem_pestat] mean and std.dev: (284.31, 135.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 943)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
sorting block 73, #reads = 1083873 mem = 536879244 peak = 1153376256
[M::process] read 688800 sequences (100000102 bp) in 2.340 CPU sec, 2.544 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (13, 286877, 15, 10)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 292, 676)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1706)
[M::mem_pestat] mean and std.dev: (399.38, 247.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2221)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 262, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 759)
[M::mem_pestat] mean and std.dev: (285.77, 136.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 952)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (122, 239, 753)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2015)
[M::mem_pestat] mean and std.dev: (486.80, 500.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2646)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 317, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1023)
[M::mem_pestat] mean and std.dev: (246.00, 132.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1319)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 689008 reads in 157.668 CPU sec, 5.111 real sec
[M::mem_process_seqs] Processed 688766 reads in 104.766 CPU sec, 3.384 real sec
[M::process] read 688664 sequences (100000053 bp) in 1.929 CPU sec, 1.972 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (12, 287083, 6, 11)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (281, 304, 395)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (53, 623)
[M::mem_pestat] mean and std.dev: (300.33, 97.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 737)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 262, 375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 767)
[M::mem_pestat] mean and std.dev: (286.75, 138.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 963)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 194, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (115, 255)
[M::mem_pestat] mean and std.dev: (193.57, 9.47)
[M::mem_pestat] low and high boundaries for proper pairs: (87, 283)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 74, #reads = 1084556 mem = 536878896 peak = 1153376256
[M::process] read 688468 sequences (100000199 bp) in 2.161 CPU sec, 2.523 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (15, 287037, 12, 9)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 223, 402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 804)
[M::mem_pestat] mean and std.dev: (222.75, 97.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1005)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 263, 375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 767)
[M::mem_pestat] mean and std.dev: (287.06, 138.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 963)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 207, 207)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (147, 247)
[M::mem_pestat] mean and std.dev: (202.00, 8.66)
[M::mem_pestat] low and high boundaries for proper pairs: (127, 267)
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_process_seqs] Processed 688800 reads in 156.811 CPU sec, 5.116 real sec
[M::mem_process_seqs] Processed 688664 reads in 105.333 CPU sec, 3.410 real sec
[M::process] read 694342 sequences (100000183 bp) in 1.950 CPU sec, 2.053 real sec...
sorting block 75, #reads = 1083717 mem = 536883013 peak = 1153376256
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 286709, 2, 14)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 262, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 555)
[M::mem_pestat] mean and std.dev: (252.68, 85.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 668)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 265, 379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 777)
[M::mem_pestat] mean and std.dev: (289.60, 140.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 976)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 222, 1238)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3402)
[M::mem_pestat] mean and std.dev: (468.08, 513.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4484)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 698594 sequences (100000100 bp) in 2.556 CPU sec, 2.856 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (15, 288762, 9, 13)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 357, 568)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1398)
[M::mem_pestat] mean and std.dev: (326.15, 195.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1813)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 243, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 723)
[M::mem_pestat] mean and std.dev: (270.52, 133.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 908)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 201, 741)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1895)
[M::mem_pestat] mean and std.dev: (277.64, 190.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2472)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 688468 reads in 167.507 CPU sec, 5.500 real sec
[M::mem_process_seqs] Processed 694342 reads in 115.738 CPU sec, 3.780 real sec
[M::process] read 697450 sequences (100000289 bp) in 2.214 CPU sec, 2.337 real sec...
sorting block 76, #reads = 1083750 mem = 536878166 peak = 1153376256
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (10, 289925, 5, 8)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (125, 218, 271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 563)
[M::mem_pestat] mean and std.dev: (195.90, 69.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 709)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 229, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 676)
[M::mem_pestat] mean and std.dev: (256.11, 126.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 848)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::process] read 695542 sequences (100000234 bp) in 2.644 CPU sec, 2.954 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (7, 289661, 10, 15)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 232, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (260.55, 129.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (77, 449, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1193)
[M::mem_pestat] mean and std.dev: (293.25, 201.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1565)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 215, 272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 466)
[M::mem_pestat] mean and std.dev: (201.57, 56.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 563)
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698594 reads in 175.170 CPU sec, 5.725 real sec
sorting block 77, #reads = 1083286 mem = 536877637 peak = 1153376256
[M::mem_process_seqs] Processed 697450 reads in 115.601 CPU sec, 3.753 real sec
[M::process] read 694644 sequences (100000079 bp) in 1.822 CPU sec, 1.906 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (10, 289673, 0, 7)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 454, 704)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1770)
[M::mem_pestat] mean and std.dev: (469.80, 282.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2303)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 240, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 718)
[M::mem_pestat] mean and std.dev: (267.84, 133.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 902)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
sorting block 78, #reads = 1088174 mem = 536879248 peak = 1180000256
[M::process] read 694118 sequences (100000213 bp) in 2.564 CPU sec, 2.916 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (12, 289217, 6, 11)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 184, 965)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2607)
[M::mem_pestat] mean and std.dev: (427.83, 472.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3428)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 243, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 734)
[M::mem_pestat] mean and std.dev: (271.63, 135.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 923)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 258, 805)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2083)
[M::mem_pestat] mean and std.dev: (467.18, 400.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2722)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695542 reads in 165.083 CPU sec, 5.473 real sec
[M::process] read 693400 sequences (100000087 bp) in 2.162 CPU sec, 2.352 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (17, 288772, 4, 13)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 303, 473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1055)
[M::mem_pestat] mean and std.dev: (301.31, 145.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1346)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 245, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 738)
[M::mem_pestat] mean and std.dev: (273.18, 136.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 928)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 291, 952)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2520)
[M::mem_pestat] mean and std.dev: (497.58, 358.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3304)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694118 reads in 91.698 CPU sec, 2.984 real sec
sorting block 79, #reads = 1086949 mem = 536878948 peak = 1180000256
[M::process] read 692892 sequences (100000062 bp) in 2.148 CPU sec, 2.311 real sec...
[M::mem_process_seqs] Processed 694644 reads in 266.161 CPU sec, 8.756 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (10, 288395, 8, 5)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 267, 408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 838)
[M::mem_pestat] mean and std.dev: (313.20, 195.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1097)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 247, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 743)
[M::mem_pestat] mean and std.dev: (275.82, 137.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 934)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (8, 288682, 4, 6)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 249, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 747)
[M::mem_pestat] mean and std.dev: (277.17, 138.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 939)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
sorting block 80, #reads = 1087400 mem = 536877656 peak = 1180000256
[M::process] read 692292 sequences (100000218 bp) in 2.512 CPU sec, 2.882 real sec...
[M::mem_process_seqs] Processed 693400 reads in 180.755 CPU sec, 5.916 real sec
[M::mem_process_seqs] Processed 692892 reads in 108.222 CPU sec, 3.538 real sec
[M::process] read 691988 sequences (100000002 bp) in 2.261 CPU sec, 2.500 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (12, 288677, 14, 8)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 177, 280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 518)
[M::mem_pestat] mean and std.dev: (212.73, 101.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 637)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 252, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (280.01, 138.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 956)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (9, 748, 944)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2814)
[M::mem_pestat] mean and std.dev: (473.92, 548.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3749)
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
sorting block 81, #reads = 1086964 mem = 536880472 peak = 1180000256
[M::process] read 691712 sequences (100000047 bp) in 2.235 CPU sec, 2.483 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (7, 288232, 5, 19)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 254, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (281.63, 139.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 961)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 345, 1050)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2710)
[M::mem_pestat] mean and std.dev: (361.62, 270.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3540)
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 692292 reads in 163.197 CPU sec, 5.356 real sec
[M::mem_process_seqs] Processed 691988 reads in 108.258 CPU sec, 3.527 real sec
[M::process] read 691198 sequences (100000187 bp) in 2.327 CPU sec, 2.548 real sec...
sorting block 82, #reads = 1087153 mem = 536877169 peak = 1180000256
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (8, 288189, 8, 15)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 255, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 770)
[M::mem_pestat] mean and std.dev: (282.86, 140.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 969)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 679, 1495)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4091)
[M::mem_pestat] mean and std.dev: (700.67, 537.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5389)
[M::mem_pestat] skip orientation RR
[M::process] read 691154 sequences (100000248 bp) in 2.303 CPU sec, 2.565 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 287792, 5, 11)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 221, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 752)
[M::mem_pestat] mean and std.dev: (234.78, 127.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 258, 376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 778)
[M::mem_pestat] mean and std.dev: (285.24, 141.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 979)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (279, 348, 1512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3978)
[M::mem_pestat] mean and std.dev: (722.90, 652.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5211)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 691712 reads in 164.438 CPU sec, 5.394 real sec
[M::mem_process_seqs] Processed 691198 reads in 108.844 CPU sec, 3.550 real sec
sorting block 83, #reads = 1086115 mem = 536879461 peak = 1180000256
[M::process] read 690672 sequences (100000141 bp) in 2.250 CPU sec, 2.442 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (17, 287721, 3, 6)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 235, 251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 465)
[M::mem_pestat] mean and std.dev: (203.00, 86.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 572)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 257, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 766)
[M::mem_pestat] mean and std.dev: (283.61, 139.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 963)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (14, 287448, 6, 20)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 407, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 853)
[M::mem_pestat] mean and std.dev: (354.92, 183.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1090)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 259, 375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (285.79, 141.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 972)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 878, 5246)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 15230)
[M::mem_pestat] mean and std.dev: (1978.40, 2193.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 20222)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 690266 sequences (100000180 bp) in 2.558 CPU sec, 2.816 real sec...
sorting block 84, #reads = 1085818 mem = 536879036 peak = 1180000256
[M::mem_process_seqs] Processed 691154 reads in 168.437 CPU sec, 5.513 real sec
[M::mem_process_seqs] Processed 690672 reads in 112.025 CPU sec, 3.646 real sec
[M::process] read 690096 sequences (100000097 bp) in 2.044 CPU sec, 2.264 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 287368, 8, 11)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (286, 302, 2544)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7060)
[M::mem_pestat] mean and std.dev: (1049.90, 1156.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9318)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 260, 375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 771)
[M::mem_pestat] mean and std.dev: (286.22, 140.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 969)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 432, 993)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2517)
[M::mem_pestat] mean and std.dev: (665.18, 652.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3279)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 85, #reads = 1084805 mem = 536880637 peak = 1180000256
[M::process] read 689976 sequences (100000060 bp) in 2.322 CPU sec, 2.648 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 287112, 2, 17)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 605, 1512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4112)
[M::mem_pestat] mean and std.dev: (741.04, 542.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5412)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 260, 375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 771)
[M::mem_pestat] mean and std.dev: (285.94, 139.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 969)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 287, 395)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709)
[M::mem_pestat] mean and std.dev: (280.86, 86.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 690266 reads in 167.516 CPU sec, 5.469 real sec
[M::mem_process_seqs] Processed 690096 reads in 111.137 CPU sec, 3.606 real sec
[M::process] read 690290 sequences (100000098 bp) in 1.952 CPU sec, 2.073 real sec...
sorting block 86, #reads = 1083342 mem = 536882203 peak = 1180000256
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (11, 286964, 2, 6)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 526, 1167)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3037)
[M::mem_pestat] mean and std.dev: (476.78, 350.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3972)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 258, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (284.06, 138.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 960)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::process] read 690070 sequences (100000070 bp) in 2.469 CPU sec, 2.907 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (16, 287282, 3, 7)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 524, 1366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3626)
[M::mem_pestat] mean and std.dev: (867.00, 822.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4756)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 258, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (283.78, 138.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 956)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::mem_process_seqs] Processed 689976 reads in 168.478 CPU sec, 5.473 real sec
[M::mem_process_seqs] Processed 690290 reads in 112.463 CPU sec, 3.633 real sec
[M::process] read 689602 sequences (100000291 bp) in 2.132 CPU sec, 2.287 real sec...
sorting block 87, #reads = 1083161 mem = 536878784 peak = 1180000256
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (11, 287135, 6, 17)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 337, 486)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1086)
[M::mem_pestat] mean and std.dev: (266.44, 127.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1386)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 258, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (283.69, 138.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 956)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 250, 426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 908)
[M::mem_pestat] mean and std.dev: (273.18, 112.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1149)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 689752 sequences (100000018 bp) in 2.431 CPU sec, 2.782 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (13, 287557, 6, 11)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (281, 281, 972)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2354)
[M::mem_pestat] mean and std.dev: (470.62, 355.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3045)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 259, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (284.95, 138.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 961)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (425, 598, 2821)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7613)
[M::mem_pestat] mean and std.dev: (1013.33, 1031.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10009)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 690070 reads in 170.161 CPU sec, 5.534 real sec
sorting block 88, #reads = 1082492 mem = 536877195 peak = 1180000256
[M::mem_process_seqs] Processed 689602 reads in 111.981 CPU sec, 3.603 real sec
[M::process] read 689688 sequences (100000056 bp) in 1.886 CPU sec, 2.007 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (14, 287782, 4, 11)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 326, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (4, 594)
[M::mem_pestat] mean and std.dev: (282.75, 85.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 712)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 259, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (284.96, 139.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 961)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 159, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 545)
[M::mem_pestat] mean and std.dev: (151.22, 51.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 688)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 89, #reads = 1082215 mem = 536878499 peak = 1180000256
[M::process] read 689618 sequences (100000208 bp) in 2.481 CPU sec, 2.961 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (12, 286697, 6, 9)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 308, 516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1172)
[M::mem_pestat] mean and std.dev: (333.73, 154.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1500)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 258, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (283.72, 137.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::mem_process_seqs] Processed 689752 reads in 169.498 CPU sec, 5.521 real sec
[M::mem_process_seqs] Processed 689688 reads in 113.218 CPU sec, 3.665 real sec
[M::process] read 689368 sequences (100000054 bp) in 2.001 CPU sec, 2.079 real sec...
sorting block 90, #reads = 1084027 mem = 536878420 peak = 1180000256
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (12, 287375, 9, 14)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 175, 209)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (83, 293)
[M::mem_pestat] mean and std.dev: (177.73, 41.82)
[M::mem_pestat] low and high boundaries for proper pairs: (10, 345)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 259, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 759)
[M::mem_pestat] mean and std.dev: (283.98, 137.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 953)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 374, 543)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1353)
[M::mem_pestat] mean and std.dev: (374.31, 235.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1758)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 689126 sequences (100000225 bp) in 2.504 CPU sec, 2.846 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (8, 286853, 9, 13)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 260, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (285.05, 137.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 196, 610)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1494)
[M::mem_pestat] mean and std.dev: (374.62, 292.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1936)
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 689618 reads in 170.495 CPU sec, 5.538 real sec
[M::mem_process_seqs] Processed 689368 reads in 112.683 CPU sec, 3.647 real sec
[M::process] read 689500 sequences (100000066 bp) in 1.905 CPU sec, 2.014 real sec...
sorting block 91, #reads = 1081332 mem = 536879260 peak = 1180000256
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (11, 286724, 0, 13)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 208, 2132)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5982)
[M::mem_pestat] mean and std.dev: (428.78, 603.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7907)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 261, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (285.56, 138.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 958)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 356, 1206)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3214)
[M::mem_pestat] mean and std.dev: (510.73, 401.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4218)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 689218 sequences (100000026 bp) in 2.479 CPU sec, 2.764 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (6, 286716, 9, 16)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 259, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (285.10, 138.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 961)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 216, 790)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2054)
[M::mem_pestat] mean and std.dev: (402.50, 399.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2686)
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 689126 reads in 166.186 CPU sec, 5.403 real sec
[M::mem_process_seqs] Processed 689500 reads in 110.642 CPU sec, 3.559 real sec
[M::process] read 689024 sequences (100000258 bp) in 2.151 CPU sec, 2.247 real sec...
sorting block 92, #reads = 1082932 mem = 536879488 peak = 1180000256
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (11, 286770, 4, 12)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 289, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 651)
[M::mem_pestat] mean and std.dev: (242.44, 85.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 804)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 261, 376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 772)
[M::mem_pestat] mean and std.dev: (287.11, 140.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 970)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 292, 637)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1481)
[M::mem_pestat] mean and std.dev: (284.00, 137.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1903)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 688864 sequences (100000082 bp) in 2.564 CPU sec, 2.851 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (7, 287116, 3, 14)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 263, 379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 779)
[M::mem_pestat] mean and std.dev: (288.85, 141.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 979)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 261, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 625)
[M::mem_pestat] mean and std.dev: (249.69, 111.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 772)
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 689218 reads in 168.566 CPU sec, 5.442 real sec
sorting block 93, #reads = 1081708 mem = 536878623 peak = 1180000256
[M::process] read 698410 sequences (100000245 bp) in 1.777 CPU sec, 1.814 real sec...
[M::mem_process_seqs] Processed 689024 reads in 112.256 CPU sec, 3.570 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (18, 287189, 7, 4)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 253, 533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1147)
[M::mem_pestat] mean and std.dev: (343.29, 161.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1454)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 262, 379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 779)
[M::mem_pestat] mean and std.dev: (288.66, 141.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 979)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
sorting block 94, #reads = 1081666 mem = 536880300 peak = 1201004544
[M::process] read 700572 sequences (100000264 bp) in 2.469 CPU sec, 2.590 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (12, 290366, 6, 16)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 347, 592)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1356)
[M::mem_pestat] mean and std.dev: (337.00, 168.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1738)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 230, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 677)
[M::mem_pestat] mean and std.dev: (256.46, 126.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 849)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (302, 306, 481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 839)
[M::mem_pestat] mean and std.dev: (329.57, 101.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1018)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 700740 sequences (100000163 bp) in 1.848 CPU sec, 1.858 real sec...
[M::mem_process_seqs] Processed 688864 reads in 173.476 CPU sec, 5.538 real sec
[M::mem_process_seqs] Processed 698410 reads in 116.451 CPU sec, 3.688 real sec
sorting block 95, #reads = 1080891 mem = 536881533 peak = 1201004544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (9, 290722, 3, 15)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 224, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 652)
[M::mem_pestat] mean and std.dev: (248.81, 121.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 817)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (310, 365, 1077)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2611)
[M::mem_pestat] mean and std.dev: (423.38, 354.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3378)
[M::mem_pestat] skip orientation RR
[M::process] read 699372 sequences (100000139 bp) in 2.452 CPU sec, 2.565 real sec...
[M::process] read 697748 sequences (100000194 bp) in 1.980 CPU sec, 1.981 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (8, 291121, 8, 9)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 224, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 658)
[M::mem_pestat] mean and std.dev: (249.67, 121.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 825)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_process_seqs] Processed 700572 reads in 178.118 CPU sec, 5.657 real sec
[M::mem_process_seqs] Processed 700740 reads in 114.942 CPU sec, 3.637 real sec
sorting block 96, #reads = 1085274 mem = 536879366 peak = 1201004544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (13, 290769, 1, 14)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 223, 743)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1901)
[M::mem_pestat] mean and std.dev: (293.27, 220.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2480)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 227, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 669)
[M::mem_pestat] mean and std.dev: (253.40, 123.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 839)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 262, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 789)
[M::mem_pestat] mean and std.dev: (223.00, 90.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1004)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 696864 sequences (100000070 bp) in 2.670 CPU sec, 2.781 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (14, 290149, 5, 11)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 815, 953)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2425)
[M::mem_pestat] mean and std.dev: (707.29, 603.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3161)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 232, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (258.75, 126.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 862)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (141, 149, 217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 369)
[M::mem_pestat] mean and std.dev: (155.40, 43.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 445)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 695856 sequences (100000077 bp) in 1.910 CPU sec, 1.908 real sec...
[M::mem_process_seqs] Processed 699372 reads in 166.785 CPU sec, 5.278 real sec
sorting block 97, #reads = 1084250 mem = 536879847 peak = 1201004544
[M::mem_process_seqs] Processed 697748 reads in 104.517 CPU sec, 3.302 real sec
sorting block 98, #reads = 1085034 mem = 536880195 peak = 1201004544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (8, 290334, 2, 14)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 235, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (262.15, 128.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 262, 407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 807)
[M::mem_pestat] mean and std.dev: (232.09, 70.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1007)
[M::mem_pestat] skip orientation RR
[M::process] read 695876 sequences (100000173 bp) in 2.659 CPU sec, 2.782 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (10, 289307, 10, 5)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 1143, 1146)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3026)
[M::mem_pestat] mean and std.dev: (830.60, 571.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3966)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 237, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 708)
[M::mem_pestat] mean and std.dev: (264.62, 130.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 889)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (749, 809, 815)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (617, 947)
[M::mem_pestat] mean and std.dev: (790.67, 29.54)
[M::mem_pestat] low and high boundaries for proper pairs: (551, 1013)
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::process] read 695300 sequences (100000057 bp) in 1.870 CPU sec, 1.875 real sec...
[M::mem_process_seqs] Processed 696864 reads in 159.558 CPU sec, 5.049 real sec
[M::mem_process_seqs] Processed 695856 reads in 102.785 CPU sec, 3.240 real sec
sorting block 99, #reads = 1083737 mem = 536882017 peak = 1201004544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (12, 289907, 12, 8)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 176, 574)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1428)
[M::mem_pestat] mean and std.dev: (333.00, 314.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1855)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 239, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 717)
[M::mem_pestat] mean and std.dev: (266.64, 131.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 901)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (74, 900, 1319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3809)
[M::mem_pestat] mean and std.dev: (715.92, 572.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5054)
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::process] read 695290 sequences (100000042 bp) in 2.783 CPU sec, 2.905 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (18, 289614, 9, 14)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 448, 1009)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2619)
[M::mem_pestat] mean and std.dev: (575.00, 395.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3424)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 242, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 730)
[M::mem_pestat] mean and std.dev: (269.69, 133.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 918)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 199, 231)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (12, 377)
[M::mem_pestat] mean and std.dev: (189.77, 38.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 450)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695876 reads in 157.505 CPU sec, 4.980 real sec
[M::process] read 694258 sequences (100000032 bp) in 1.920 CPU sec, 1.912 real sec...
[M::mem_process_seqs] Processed 695300 reads in 100.786 CPU sec, 3.172 real sec
sorting block 100, #reads = 1082940 mem = 536883355 peak = 1201004544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (10, 289499, 3, 9)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 206, 769)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2023)
[M::mem_pestat] mean and std.dev: (421.22, 546.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2650)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 241, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 724)
[M::mem_pestat] mean and std.dev: (268.58, 132.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 910)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::process] read 693716 sequences (100000045 bp) in 2.528 CPU sec, 2.636 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (11, 289331, 9, 12)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 260, 263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (35, 415)
[M::mem_pestat] mean and std.dev: (217.50, 49.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 491)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 244, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 729)
[M::mem_pestat] mean and std.dev: (270.70, 132.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 916)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 391, 1723)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4791)
[M::mem_pestat] mean and std.dev: (956.58, 949.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6325)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695290 reads in 155.701 CPU sec, 4.933 real sec
[M::process] read 692972 sequences (100000138 bp) in 1.888 CPU sec, 1.892 real sec...
sorting block 101, #reads = 1084981 mem = 536880022 peak = 1201004544
[M::mem_process_seqs] Processed 694258 reads in 100.022 CPU sec, 3.145 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (7, 288400, 7, 10)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 248, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 742)
[M::mem_pestat] mean and std.dev: (274.52, 135.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 933)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 838, 838)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2072)
[M::mem_pestat] mean and std.dev: (581.67, 466.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2689)
[M::mem_pestat] skip orientation RR
sorting block 102, #reads = 1084436 mem = 536878879 peak = 1201004544
[M::process] read 692348 sequences (100000276 bp) in 2.186 CPU sec, 2.298 real sec...
[M::process] read 691672 sequences (100000284 bp) in 1.500 CPU sec, 1.503 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 288534, 11, 13)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (255, 407, 551)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1143)
[M::mem_pestat] mean and std.dev: (377.10, 133.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1439)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 251, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (277.76, 137.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 947)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (25, 4029, 4029)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12037)
[M::mem_pestat] mean and std.dev: (2767.09, 2160.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16041)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 363, 433)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 967)
[M::mem_pestat] mean and std.dev: (328.00, 213.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1234)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 693716 reads in 156.293 CPU sec, 4.967 real sec
[M::mem_process_seqs] Processed 692972 reads in 101.591 CPU sec, 3.224 real sec
sorting block 103, #reads = 1083079 mem = 536878858 peak = 1201004544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 288498, 9, 8)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 248, 252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (48, 388)
[M::mem_pestat] mean and std.dev: (219.56, 68.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 492)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 252, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (279.86, 138.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 956)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::process] read 691058 sequences (100000148 bp) in 2.544 CPU sec, 2.644 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (14, 287994, 4, 14)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 325, 1503)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4229)
[M::mem_pestat] mean and std.dev: (598.14, 580.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5592)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 254, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (280.89, 138.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 953)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 247, 498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1002)
[M::mem_pestat] mean and std.dev: (338.15, 199.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1254)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 690518 sequences (100000172 bp) in 1.860 CPU sec, 1.861 real sec...
[M::mem_process_seqs] Processed 692348 reads in 156.409 CPU sec, 4.947 real sec
[M::mem_process_seqs] Processed 691672 reads in 101.134 CPU sec, 3.187 real sec
sorting block 104, #reads = 1083043 mem = 536882963 peak = 1201004544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (15, 288007, 3, 19)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 311, 800)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1968)
[M::mem_pestat] mean and std.dev: (394.23, 424.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2552)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 255, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (282.00, 138.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 951)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 206, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 791)
[M::mem_pestat] mean and std.dev: (257.88, 147.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1001)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 690628 sequences (100000228 bp) in 2.788 CPU sec, 2.898 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (18, 287461, 3, 8)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 428, 607)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1403)
[M::mem_pestat] mean and std.dev: (374.94, 199.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1801)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 257, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (283.08, 138.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 956)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::mem_process_seqs] Processed 691058 reads in 157.174 CPU sec, 4.972 real sec
[M::process] read 690296 sequences (100000082 bp) in 1.879 CPU sec, 1.883 real sec...
[M::mem_process_seqs] Processed 690518 reads in 101.726 CPU sec, 3.202 real sec
sorting block 105, #reads = 1081956 mem = 536878943 peak = 1201004544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (9, 287751, 12, 8)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 256, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (282.44, 138.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 951)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (28, 610, 1676)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4972)
[M::mem_pestat] mean and std.dev: (873.83, 1077.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6620)
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation RF
[M::process] read 689986 sequences (100000144 bp) in 2.541 CPU sec, 2.639 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (8, 287469, 8, 15)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 257, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (283.64, 138.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 956)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 270, 413)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 775)
[M::mem_pestat] mean and std.dev: (330.53, 125.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 956)
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 690628 reads in 154.007 CPU sec, 4.879 real sec
[M::process] read 690178 sequences (100000220 bp) in 1.750 CPU sec, 1.751 real sec...
sorting block 106, #reads = 1082031 mem = 536879225 peak = 1201004544
[M::mem_process_seqs] Processed 690296 reads in 99.909 CPU sec, 3.146 real sec
sorting block 107, #reads = 1081975 mem = 536877798 peak = 1201004544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (7, 287828, 6, 14)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 258, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 759)
[M::mem_pestat] mean and std.dev: (284.17, 138.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 953)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 304, 533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1171)
[M::mem_pestat] mean and std.dev: (392.43, 265.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1490)
[M::mem_pestat] skip orientation RR
[M::process] read 690334 sequences (100000173 bp) in 2.767 CPU sec, 2.870 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (10, 287460, 10, 17)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 200, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 716)
[M::mem_pestat] mean and std.dev: (183.00, 77.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 909)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 258, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 767)
[M::mem_pestat] mean and std.dev: (284.19, 138.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 964)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 824, 1275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3541)
[M::mem_pestat] mean and std.dev: (685.00, 524.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4674)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 267, 1414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3904)
[M::mem_pestat] mean and std.dev: (1000.88, 1254.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6019)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 689986 reads in 154.427 CPU sec, 4.880 real sec
[M::process] read 689688 sequences (100000234 bp) in 1.899 CPU sec, 1.905 real sec...
[M::mem_process_seqs] Processed 690178 reads in 100.983 CPU sec, 3.174 real sec
sorting block 108, #reads = 1083279 mem = 536878557 peak = 1201004544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (13, 287562, 3, 11)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 345, 1242)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3314)
[M::mem_pestat] mean and std.dev: (647.08, 581.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4350)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 257, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 752)
[M::mem_pestat] mean and std.dev: (282.16, 137.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 944)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (351, 379, 1071)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2511)
[M::mem_pestat] mean and std.dev: (403.00, 251.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3231)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 689176 sequences (100000030 bp) in 2.176 CPU sec, 2.293 real sec...
[M::process] read 688902 sequences (100000031 bp) in 1.459 CPU sec, 1.459 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (14, 287271, 6, 16)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (125, 229, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 809)
[M::mem_pestat] mean and std.dev: (212.46, 96.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1037)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 259, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 768)
[M::mem_pestat] mean and std.dev: (285.49, 139.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 965)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (359, 468, 1725)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4457)
[M::mem_pestat] mean and std.dev: (1150.69, 1380.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6674)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 690334 reads in 160.414 CPU sec, 5.110 real sec
[M::mem_process_seqs] Processed 689688 reads in 101.546 CPU sec, 3.228 real sec
sorting block 109, #reads = 1082486 mem = 536880489 peak = 1201004544
[M::process] read 689108 sequences (100000196 bp) in 2.487 CPU sec, 2.601 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (11, 287299, 1, 9)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 281, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1059)
[M::mem_pestat] mean and std.dev: (332.18, 246.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1367)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 262, 377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (288.11, 140.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 971)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::mem_process_seqs] Processed 688902 reads in 83.658 CPU sec, 2.627 real sec
[M::process] read 690198 sequences (100000174 bp) in 1.884 CPU sec, 1.896 real sec...
sorting block 110, #reads = 1082604 mem = 536879495 peak = 1201004544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (16, 286906, 2, 5)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 231, 1355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3717)
[M::mem_pestat] mean and std.dev: (874.50, 1098.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5267)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 261, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 766)
[M::mem_pestat] mean and std.dev: (286.49, 139.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 962)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (9, 286569, 4, 11)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 261, 377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (287.87, 140.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 971)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (302, 323, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (343.00, 139.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 914)
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 689176 reads in 234.367 CPU sec, 7.431 real sec
[M::process] read 694934 sequences (100000257 bp) in 2.022 CPU sec, 2.049 real sec...
[M::mem_process_seqs] Processed 689108 reads in 114.951 CPU sec, 3.630 real sec
sorting block 111, #reads = 1082517 mem = 536879765 peak = 1201004544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (15, 287417, 3, 10)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 252, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1002)
[M::mem_pestat] mean and std.dev: (293.29, 174.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1274)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 255, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (283.12, 139.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 952)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (282, 1492, 1510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3966)
[M::mem_pestat] mean and std.dev: (726.62, 603.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5194)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 699078 sequences (100000099 bp) in 2.475 CPU sec, 2.635 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (14, 288648, 4, 12)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (122, 175, 250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 506)
[M::mem_pestat] mean and std.dev: (182.42, 78.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 634)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 242, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 722)
[M::mem_pestat] mean and std.dev: (269.46, 133.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 907)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (140, 148, 266)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 518)
[M::mem_pestat] mean and std.dev: (197.33, 105.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 644)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 697978 sequences (100000013 bp) in 1.840 CPU sec, 1.839 real sec...
[M::mem_process_seqs] Processed 690198 reads in 167.435 CPU sec, 5.327 real sec
sorting block 112, #reads = 1082461 mem = 536876893 peak = 1201004544
[M::mem_process_seqs] Processed 694934 reads in 111.217 CPU sec, 3.508 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (15, 290769, 4, 9)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 217, 270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (48, 418)
[M::mem_pestat] mean and std.dev: (215.67, 60.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 492)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 228, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 675)
[M::mem_pestat] mean and std.dev: (254.64, 125.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 847)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::process] read 697172 sequences (100000272 bp) in 2.478 CPU sec, 2.628 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 289288, 5, 11)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 326, 433)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 991)
[M::mem_pestat] mean and std.dev: (293.90, 123.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1270)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 233, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (259.27, 127.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 869)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 240, 399)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 927)
[M::mem_pestat] mean and std.dev: (235.64, 115.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1191)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699078 reads in 151.193 CPU sec, 4.787 real sec
sorting block 113, #reads = 1079578 mem = 536881483 peak = 1201004544
[M::process] read 696508 sequences (100000029 bp) in 1.921 CPU sec, 1.931 real sec...
[M::mem_process_seqs] Processed 697978 reads in 95.828 CPU sec, 3.014 real sec
sorting block 114, #reads = 1089538 mem = 536876382 peak = 1201004544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (11, 289575, 7, 16)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 241, 647)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1537)
[M::mem_pestat] mean and std.dev: (343.64, 221.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1982)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 236, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (262.14, 128.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 464, 757)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1787)
[M::mem_pestat] mean and std.dev: (543.81, 382.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2302)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 695286 sequences (100000080 bp) in 2.450 CPU sec, 2.560 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (8, 289586, 1, 13)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 239, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 713)
[M::mem_pestat] mean and std.dev: (265.07, 130.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 896)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (301, 316, 4350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12448)
[M::mem_pestat] mean and std.dev: (1661.85, 2451.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16497)
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697172 reads in 147.304 CPU sec, 4.680 real sec
[M::mem_process_seqs] Processed 696508 reads in 94.552 CPU sec, 2.971 real sec
[M::process] read 694656 sequences (100000029 bp) in 2.061 CPU sec, 2.116 real sec...
sorting block 115, #reads = 1089368 mem = 536878649 peak = 1201004544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (8, 288910, 4, 7)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 240, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709)
[M::mem_pestat] mean and std.dev: (266.21, 129.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 890)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::process] read 694320 sequences (100000022 bp) in 2.385 CPU sec, 2.519 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (9, 289078, 9, 11)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 244, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 725)
[M::mem_pestat] mean and std.dev: (269.56, 132.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 911)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 253, 1315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3531)
[M::mem_pestat] mean and std.dev: (698.09, 771.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4639)
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695286 reads in 145.940 CPU sec, 4.642 real sec
[M::mem_process_seqs] Processed 694656 reads in 94.435 CPU sec, 2.973 real sec
[M::process] read 693566 sequences (100000270 bp) in 2.158 CPU sec, 2.199 real sec...
sorting block 116, #reads = 1089500 mem = 536877906 peak = 1201004544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (16, 289311, 4, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 229, 282)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (6, 466)
[M::mem_pestat] mean and std.dev: (226.25, 44.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 558)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 246, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 726)
[M::mem_pestat] mean and std.dev: (270.86, 132.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 912)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 293, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 662)
[M::mem_pestat] mean and std.dev: (254.81, 78.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 818)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 693490 sequences (100000249 bp) in 2.195 CPU sec, 2.309 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (9, 289124, 3, 16)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 247, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 733)
[M::mem_pestat] mean and std.dev: (272.63, 132.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 921)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (306, 310, 555)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1053)
[M::mem_pestat] mean and std.dev: (360.53, 143.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1302)
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694320 reads in 144.891 CPU sec, 4.596 real sec
[M::process] read 693390 sequences (100000252 bp) in 1.793 CPU sec, 1.813 real sec...
sorting block 117, #reads = 1088341 mem = 536877609 peak = 1201004544
[M::mem_process_seqs] Processed 693566 reads in 91.921 CPU sec, 2.894 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (12, 288398, 10, 7)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 181, 818)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2172)
[M::mem_pestat] mean and std.dev: (361.50, 334.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2849)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 249, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 737)
[M::mem_pestat] mean and std.dev: (274.18, 133.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 926)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (81, 210, 1431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4131)
[M::mem_pestat] mean and std.dev: (550.10, 596.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5481)
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
sorting block 118, #reads = 1089180 mem = 536878561 peak = 1201004544
[M::process] read 693608 sequences (100000119 bp) in 2.441 CPU sec, 2.582 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (17, 288941, 3, 7)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 190, 229)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (25, 365)
[M::mem_pestat] mean and std.dev: (194.82, 49.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 433)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 248, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 737)
[M::mem_pestat] mean and std.dev: (273.99, 133.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 926)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::mem_process_seqs] Processed 693490 reads in 155.686 CPU sec, 4.945 real sec
[M::process] read 693148 sequences (100000025 bp) in 1.835 CPU sec, 1.847 real sec...
[M::mem_process_seqs] Processed 693390 reads in 95.685 CPU sec, 3.007 real sec
sorting block 119, #reads = 1084913 mem = 536876168 peak = 1201004544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (15, 288999, 7, 15)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (415, 419, 479)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (287, 607)
[M::mem_pestat] mean and std.dev: (443.89, 31.43)
[M::mem_pestat] low and high boundaries for proper pairs: (223, 671)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 247, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 739)
[M::mem_pestat] mean and std.dev: (273.63, 134.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 929)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 278, 642)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1454)
[M::mem_pestat] mean and std.dev: (290.38, 172.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1860)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 692660 sequences (100000245 bp) in 2.446 CPU sec, 2.559 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (16, 288056, 10, 6)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 299, 422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 794)
[M::mem_pestat] mean and std.dev: (294.40, 110.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 980)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 250, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 738)
[M::mem_pestat] mean and std.dev: (274.97, 133.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 927)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (546, 604, 5888)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 16572)
[M::mem_pestat] mean and std.dev: (2080.30, 2500.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 21914)
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_process_seqs] Processed 693608 reads in 144.775 CPU sec, 4.599 real sec
[M::mem_process_seqs] Processed 693148 reads in 93.849 CPU sec, 2.947 real sec
[M::process] read 692430 sequences (100000291 bp) in 2.071 CPU sec, 2.115 real sec...
sorting block 120, #reads = 1087664 mem = 536878997 peak = 1201004544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (16, 288798, 3, 8)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 247, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 712)
[M::mem_pestat] mean and std.dev: (231.92, 81.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 895)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 252, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 745)
[M::mem_pestat] mean and std.dev: (276.80, 134.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 936)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::process] read 693186 sequences (100000116 bp) in 2.380 CPU sec, 2.502 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (13, 288391, 7, 12)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 383, 704)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1778)
[M::mem_pestat] mean and std.dev: (333.45, 205.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2315)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 252, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 742)
[M::mem_pestat] mean and std.dev: (276.69, 134.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 932)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 1649, 1958)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5528)
[M::mem_pestat] mean and std.dev: (1033.83, 875.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7313)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 692660 reads in 145.902 CPU sec, 4.637 real sec
[M::mem_process_seqs] Processed 692430 reads in 94.235 CPU sec, 2.963 real sec
[M::process] read 692010 sequences (100000045 bp) in 1.895 CPU sec, 1.932 real sec...
sorting block 121, #reads = 1086968 mem = 536880815 peak = 1201004544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (4, 288190, 11, 16)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 248, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 725)
[M::mem_pestat] mean and std.dev: (272.23, 131.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 910)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (279, 320, 1223)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3111)
[M::mem_pestat] mean and std.dev: (654.00, 631.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4055)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 258, 890)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2352)
[M::mem_pestat] mean and std.dev: (418.60, 436.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3083)
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690942 sequences (100000139 bp) in 2.475 CPU sec, 2.609 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (7, 287724, 5, 7)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 253, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 752)
[M::mem_pestat] mean and std.dev: (279.55, 136.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 945)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_process_seqs] Processed 693186 reads in 155.886 CPU sec, 4.942 real sec
[M::process] read 691124 sequences (100000061 bp) in 1.906 CPU sec, 1.925 real sec...
sorting block 122, #reads = 1086420 mem = 536880733 peak = 1201004544
[M::mem_process_seqs] Processed 692010 reads in 102.570 CPU sec, 3.287 real sec
sorting block 123, #reads = 1084929 mem = 536882357 peak = 1201004544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (9, 287805, 8, 12)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 258, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (283.92, 138.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 960)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 220, 252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (42, 392)
[M::mem_pestat] mean and std.dev: (211.50, 64.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] skip orientation RR
[M::process] read 690480 sequences (100000165 bp) in 2.452 CPU sec, 2.595 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (6, 287669, 6, 6)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 258, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (283.14, 137.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 956)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::process] read 690360 sequences (100000234 bp) in 1.740 CPU sec, 1.736 real sec...
[M::mem_process_seqs] Processed 690942 reads in 159.836 CPU sec, 5.076 real sec
[M::mem_process_seqs] Processed 691124 reads in 104.902 CPU sec, 3.308 real sec
sorting block 124, #reads = 1084082 mem = 536878464 peak = 1201004544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (9, 287752, 10, 14)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 258, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (284.13, 139.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 960)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 543, 1219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3243)
[M::mem_pestat] mean and std.dev: (713.90, 748.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4255)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 252, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 796)
[M::mem_pestat] mean and std.dev: (290.00, 148.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1007)
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690778 sequences (100000209 bp) in 2.508 CPU sec, 2.631 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (11, 287112, 4, 12)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 288, 419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 785)
[M::mem_pestat] mean and std.dev: (330.73, 106.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 968)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 257, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (283.17, 138.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 956)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (343, 703, 1321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3277)
[M::mem_pestat] mean and std.dev: (703.55, 461.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4255)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 690508 sequences (100000006 bp) in 1.900 CPU sec, 1.897 real sec...
[M::mem_process_seqs] Processed 690480 reads in 160.463 CPU sec, 5.081 real sec
[M::mem_process_seqs] Processed 690360 reads in 103.859 CPU sec, 3.274 real sec
sorting block 125, #reads = 1082465 mem = 536878258 peak = 1201004544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (8, 287939, 5, 20)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 254, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (280.24, 136.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 942)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (126, 144, 385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 903)
[M::mem_pestat] mean and std.dev: (263.30, 195.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1162)
[M::mem_pestat] skip orientation RR
[M::process] read 690076 sequences (100000231 bp) in 2.427 CPU sec, 2.547 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (5, 287260, 10, 7)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 255, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (280.72, 135.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 939)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (374, 992, 5151)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 14705)
[M::mem_pestat] mean and std.dev: (1901.40, 2148.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 19482)
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation RF
[M::process] read 690146 sequences (100000103 bp) in 1.880 CPU sec, 1.871 real sec...
[M::mem_process_seqs] Processed 690778 reads in 162.676 CPU sec, 5.156 real sec
sorting block 126, #reads = 1082734 mem = 536879837 peak = 1201004544
[M::mem_process_seqs] Processed 690508 reads in 105.512 CPU sec, 3.330 real sec
sorting block 127, #reads = 1081314 mem = 536877133 peak = 1201004544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (18, 287621, 13, 18)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 396, 622)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1474)
[M::mem_pestat] mean and std.dev: (407.94, 247.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1900)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 257, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (283.32, 138.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 952)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (276, 792, 812)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1884)
[M::mem_pestat] mean and std.dev: (695.92, 429.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2420)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 189, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (51, 326)
[M::mem_pestat] mean and std.dev: (176.00, 36.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 381)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690114 sequences (100000062 bp) in 2.463 CPU sec, 2.565 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (8, 287492, 11, 10)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 257, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (283.59, 138.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 956)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 322, 616)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1572)
[M::mem_pestat] mean and std.dev: (307.11, 188.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2050)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 219, 540)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1282)
[M::mem_pestat] mean and std.dev: (282.22, 188.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1653)
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 689698 sequences (100000104 bp) in 1.910 CPU sec, 1.912 real sec...
[M::mem_process_seqs] Processed 690076 reads in 160.518 CPU sec, 5.083 real sec
[M::mem_process_seqs] Processed 690146 reads in 103.819 CPU sec, 3.268 real sec
sorting block 128, #reads = 1081956 mem = 536883062 peak = 1201004544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (12, 286928, 6, 8)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 226, 232)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (94, 324)
[M::mem_pestat] mean and std.dev: (186.60, 43.34)
[M::mem_pestat] low and high boundaries for proper pairs: (13, 370)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 257, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (283.16, 137.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 952)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::process] read 690090 sequences (100000212 bp) in 2.280 CPU sec, 2.389 real sec...
[M::process] read 690928 sequences (100000131 bp) in 1.500 CPU sec, 1.491 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (16, 287272, 3, 9)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 333, 1303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3491)
[M::mem_pestat] mean and std.dev: (801.88, 879.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4585)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 259, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 762)
[M::mem_pestat] mean and std.dev: (284.82, 139.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 957)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::mem_process_seqs] Processed 690114 reads in 165.841 CPU sec, 5.271 real sec
[M::mem_process_seqs] Processed 689698 reads in 106.192 CPU sec, 3.371 real sec
sorting block 129, #reads = 1080414 mem = 536881279 peak = 1201004544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (14, 287273, 11, 19)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 348, 1575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4353)
[M::mem_pestat] mean and std.dev: (974.07, 987.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5742)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 257, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (283.08, 138.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 948)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 353, 1282)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3576)
[M::mem_pestat] mean and std.dev: (434.11, 450.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4723)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 411, 789)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1929)
[M::mem_pestat] mean and std.dev: (470.12, 332.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2499)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703986 sequences (100000110 bp) in 2.549 CPU sec, 2.640 real sec...
[M::process] read 701450 sequences (100000271 bp) in 1.990 CPU sec, 1.983 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (17, 287312, 5, 14)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 227, 644)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1612)
[M::mem_pestat] mean and std.dev: (312.67, 307.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2096)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 254, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (280.58, 137.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 946)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (260, 584, 1564)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4172)
[M::mem_pestat] mean and std.dev: (868.29, 617.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5476)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 690090 reads in 181.175 CPU sec, 5.747 real sec
[M::mem_process_seqs] Processed 690928 reads in 123.738 CPU sec, 3.911 real sec
sorting block 130, #reads = 1080280 mem = 536883199 peak = 1201004544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (13, 291374, 5, 6)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 229, 1376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3834)
[M::mem_pestat] mean and std.dev: (495.92, 558.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5063)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 216, 309)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 621)
[M::mem_pestat] mean and std.dev: (239.62, 115.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 777)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::process] read 699930 sequences (100000092 bp) in 2.364 CPU sec, 2.454 real sec...
[M::process] read 699020 sequences (100000296 bp) in 1.960 CPU sec, 1.964 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (9, 290861, 6, 14)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 222, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 654)
[M::mem_pestat] mean and std.dev: (248.58, 121.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 820)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (120, 215, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 678)
[M::mem_pestat] mean and std.dev: (193.83, 86.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703986 reads in 175.372 CPU sec, 5.561 real sec
sorting block 131, #reads = 1072412 mem = 536878982 peak = 1201004544
[M::mem_process_seqs] Processed 701450 reads in 112.105 CPU sec, 3.544 real sec
sorting block 132, #reads = 1085195 mem = 536879050 peak = 1201004544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (8, 290447, 7, 11)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 228, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 672)
[M::mem_pestat] mean and std.dev: (253.60, 124.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 843)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 173, 225)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (36, 351)
[M::mem_pestat] mean and std.dev: (173.50, 60.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 417)
[M::mem_pestat] skip orientation RR
[M::process] read 697676 sequences (100000134 bp) in 2.504 CPU sec, 2.600 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (12, 290446, 13, 12)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 253, 287)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 523)
[M::mem_pestat] mean and std.dev: (201.70, 60.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 641)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 230, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (256.16, 124.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 856)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (365, 493, 635)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1175)
[M::mem_pestat] mean and std.dev: (530.23, 229.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1448)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 287, 837)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2175)
[M::mem_pestat] mean and std.dev: (421.73, 445.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2844)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696988 sequences (100000245 bp) in 1.950 CPU sec, 1.956 real sec...
[M::mem_process_seqs] Processed 699930 reads in 173.183 CPU sec, 5.490 real sec
[M::mem_process_seqs] Processed 699020 reads in 112.738 CPU sec, 3.558 real sec
sorting block 133, #reads = 1085308 mem = 536878451 peak = 1201004544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (9, 289876, 1, 6)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 234, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (260.27, 127.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::process] read 695820 sequences (100000285 bp) in 2.499 CPU sec, 2.604 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (6, 289757, 5, 8)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 237, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 703)
[M::mem_pestat] mean and std.dev: (262.69, 128.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 883)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::process] read 695570 sequences (100000190 bp) in 1.940 CPU sec, 1.943 real sec...
[M::mem_process_seqs] Processed 697676 reads in 167.701 CPU sec, 5.308 real sec
[M::mem_process_seqs] Processed 696988 reads in 108.230 CPU sec, 3.417 real sec
sorting block 134, #reads = 1083620 mem = 536880234 peak = 1201004544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (9, 289081, 8, 6)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 240, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 715)
[M::mem_pestat] mean and std.dev: (266.28, 130.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 898)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::process] read 694448 sequences (100000080 bp) in 2.518 CPU sec, 2.623 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (17, 289195, 7, 10)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 213, 871)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2259)
[M::mem_pestat] mean and std.dev: (447.65, 505.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2953)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 242, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 721)
[M::mem_pestat] mean and std.dev: (267.71, 130.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 906)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (121, 229, 421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1021)
[M::mem_pestat] mean and std.dev: (256.11, 194.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1321)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 694816 sequences (100000054 bp) in 1.950 CPU sec, 1.944 real sec...
[M::mem_process_seqs] Processed 695820 reads in 167.551 CPU sec, 5.304 real sec
sorting block 135, #reads = 1082547 mem = 536879840 peak = 1201004544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (15, 289100, 4, 3)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 366, 1324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3430)
[M::mem_pestat] mean and std.dev: (676.53, 671.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4483)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 246, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 738)
[M::mem_pestat] mean and std.dev: (272.41, 133.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 928)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::process] read 694060 sequences (100000187 bp) in 2.145 CPU sec, 2.145 real sec...
[M::mem_process_seqs] Processed 694448 reads in 90.607 CPU sec, 2.861 real sec
sorting block 136, #reads = 1083453 mem = 536879499 peak = 1201004544
[M::mem_process_seqs] Processed 695570 reads in 230.538 CPU sec, 7.295 real sec
[M::process] read 693862 sequences (100000023 bp) in 2.498 CPU sec, 2.634 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (12, 288823, 2, 17)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (372, 708, 895)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1941)
[M::mem_pestat] mean and std.dev: (617.92, 241.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2464)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 245, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 735)
[M::mem_pestat] mean and std.dev: (272.49, 134.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 924)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 354, 1339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3561)
[M::mem_pestat] mean and std.dev: (509.93, 437.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4672)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694060 reads in 94.745 CPU sec, 2.974 real sec
[M::process] read 693758 sequences (100000016 bp) in 1.904 CPU sec, 1.924 real sec...
sorting block 137, #reads = 1082279 mem = 536887549 peak = 1201004544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (11, 289438, 10, 11)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 247, 541)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1309)
[M::mem_pestat] mean and std.dev: (300.73, 195.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1693)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 243, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 734)
[M::mem_pestat] mean and std.dev: (271.22, 133.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 923)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (19, 351, 433)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1261)
[M::mem_pestat] mean and std.dev: (275.00, 287.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1675)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 204, 379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 739)
[M::mem_pestat] mean and std.dev: (252.18, 123.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 919)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (15, 288917, 2, 11)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 194, 292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 502)
[M::mem_pestat] mean and std.dev: (220.33, 50.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 607)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 248, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (275.72, 136.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 945)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 231, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 598)
[M::mem_pestat] mean and std.dev: (251.20, 72.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 732)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694816 reads in 278.005 CPU sec, 8.815 real sec
[M::mem_process_seqs] Processed 693862 reads in 126.816 CPU sec, 4.023 real sec
[M::process] read 694004 sequences (100000150 bp) in 2.312 CPU sec, 2.370 real sec...
sorting block 138, #reads = 1081664 mem = 536877877 peak = 1201004544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (17, 289027, 2, 10)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 335, 747)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1815)
[M::mem_pestat] mean and std.dev: (392.59, 221.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2349)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 248, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 740)
[M::mem_pestat] mean and std.dev: (274.45, 135.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 930)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 354, 1061)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2749)
[M::mem_pestat] mean and std.dev: (387.50, 276.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3593)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 692044 sequences (100000181 bp) in 2.460 CPU sec, 2.597 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 288459, 8, 13)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 172, 269)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 475)
[M::mem_pestat] mean and std.dev: (187.81, 57.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 578)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 243, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 717)
[M::mem_pestat] mean and std.dev: (269.42, 131.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 900)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 313, 1043)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2715)
[M::mem_pestat] mean and std.dev: (584.62, 563.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3551)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 690768 sequences (100000292 bp) in 1.860 CPU sec, 1.859 real sec...
[M::mem_process_seqs] Processed 693758 reads in 166.477 CPU sec, 5.282 real sec
[M::mem_process_seqs] Processed 694004 reads in 108.446 CPU sec, 3.423 real sec
sorting block 139, #reads = 1082913 mem = 536879811 peak = 1201004544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 287415, 6, 16)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (278, 497, 1128)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2828)
[M::mem_pestat] mean and std.dev: (533.48, 530.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3678)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 251, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 737)
[M::mem_pestat] mean and std.dev: (276.54, 133.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 925)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (336, 553, 1229)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3015)
[M::mem_pestat] mean and std.dev: (693.57, 591.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3908)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 690470 sequences (100000092 bp) in 2.301 CPU sec, 2.451 real sec...
[M::process] read 690304 sequences (100000053 bp) in 1.480 CPU sec, 1.487 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (15, 287617, 6, 11)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 195, 272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 534)
[M::mem_pestat] mean and std.dev: (186.15, 66.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 665)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 255, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (280.19, 135.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 939)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 254, 898)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2258)
[M::mem_pestat] mean and std.dev: (610.36, 599.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3007)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 692044 reads in 165.992 CPU sec, 5.280 real sec
sorting block 140, #reads = 1082710 mem = 536879117 peak = 1201004544
[M::mem_process_seqs] Processed 690768 reads in 106.767 CPU sec, 3.386 real sec
sorting block 141, #reads = 1081965 mem = 536879253 peak = 1201004544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (18, 287623, 1, 13)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (121, 353, 652)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1714)
[M::mem_pestat] mean and std.dev: (406.18, 355.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2245)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 258, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 752)
[M::mem_pestat] mean and std.dev: (281.80, 135.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 944)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 347, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 821)
[M::mem_pestat] mean and std.dev: (298.64, 120.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1014)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 690226 sequences (100000124 bp) in 2.328 CPU sec, 2.449 real sec...
[M::process] read 690334 sequences (100000144 bp) in 1.430 CPU sec, 1.430 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (16, 286813, 5, 15)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 393, 891)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2227)
[M::mem_pestat] mean and std.dev: (471.88, 347.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2895)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 257, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 746)
[M::mem_pestat] mean and std.dev: (280.64, 134.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 936)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 229, 484)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1130)
[M::mem_pestat] mean and std.dev: (264.46, 216.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1453)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 690470 reads in 164.385 CPU sec, 5.240 real sec
[M::mem_process_seqs] Processed 690304 reads in 113.120 CPU sec, 3.622 real sec
sorting block 142, #reads = 1081304 mem = 536879842 peak = 1201004544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (14, 287455, 6, 13)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (127, 250, 250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 496)
[M::mem_pestat] mean and std.dev: (213.08, 114.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 671)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 257, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 743)
[M::mem_pestat] mean and std.dev: (280.55, 134.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 932)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (269, 412, 574)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1184)
[M::mem_pestat] mean and std.dev: (466.38, 260.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1508)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 689762 sequences (100000075 bp) in 2.548 CPU sec, 2.668 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (17, 287048, 3, 13)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 196, 1971)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5613)
[M::mem_pestat] mean and std.dev: (802.41, 1048.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7434)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 255, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 734)
[M::mem_pestat] mean and std.dev: (278.18, 132.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 920)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 268, 1101)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2857)
[M::mem_pestat] mean and std.dev: (428.83, 325.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3735)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 689236 sequences (100000172 bp) in 1.870 CPU sec, 1.861 real sec...
[M::mem_process_seqs] Processed 690226 reads in 160.247 CPU sec, 5.077 real sec
sorting block 143, #reads = 1082578 mem = 536881075 peak = 1201004544
[M::mem_process_seqs] Processed 690334 reads in 104.597 CPU sec, 3.294 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 287571, 7, 10)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 408, 579)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1357)
[M::mem_pestat] mean and std.dev: (456.52, 330.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1778)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 257, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 738)
[M::mem_pestat] mean and std.dev: (279.94, 133.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 925)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (301, 564, 917)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2149)
[M::mem_pestat] mean and std.dev: (541.11, 359.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2765)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 689596 sequences (100000276 bp) in 2.800 CPU sec, 2.922 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (14, 286939, 12, 11)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 222, 242)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (95, 340)
[M::mem_pestat] mean and std.dev: (204.31, 36.02)
[M::mem_pestat] low and high boundaries for proper pairs: (46, 389)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 258, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 742)
[M::mem_pestat] mean and std.dev: (281.72, 134.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 930)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (92, 139, 1434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4118)
[M::mem_pestat] mean and std.dev: (441.27, 562.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5460)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 199, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (259.36, 121.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 869)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 689230 sequences (100000012 bp) in 1.840 CPU sec, 1.841 real sec...
[M::mem_process_seqs] Processed 689762 reads in 158.585 CPU sec, 5.010 real sec
sorting block 144, #reads = 1082468 mem = 536880225 peak = 1201004544
[M::mem_process_seqs] Processed 689236 reads in 102.532 CPU sec, 3.236 real sec
sorting block 145, #reads = 1083050 mem = 536880544 peak = 1201004544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (11, 286931, 9, 12)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 210, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 592)
[M::mem_pestat] mean and std.dev: (187.00, 74.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 735)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 259, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 747)
[M::mem_pestat] mean and std.dev: (281.69, 134.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 937)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (287, 302, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (179, 449)
[M::mem_pestat] mean and std.dev: (308.91, 27.93)
[M::mem_pestat] low and high boundaries for proper pairs: (125, 503)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 688652 sequences (100000157 bp) in 2.750 CPU sec, 2.850 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (6, 287067, 5, 18)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 261, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (285.59, 138.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 955)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 238, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (99, 369)
[M::mem_pestat] mean and std.dev: (219.88, 43.47)
[M::mem_pestat] low and high boundaries for proper pairs: (45, 423)
[M::mem_pestat] skip orientation RR
[M::process] read 688538 sequences (100000020 bp) in 1.840 CPU sec, 1.835 real sec...
[M::mem_process_seqs] Processed 689596 reads in 157.955 CPU sec, 4.993 real sec
[M::mem_process_seqs] Processed 689230 reads in 102.174 CPU sec, 3.222 real sec
sorting block 146, #reads = 1083562 mem = 536878157 peak = 1201004544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (8, 286965, 5, 12)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 262, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (285.65, 137.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 951)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 337, 884)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2364)
[M::mem_pestat] mean and std.dev: (438.00, 370.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3104)
[M::mem_pestat] skip orientation RR
[M::process] read 688822 sequences (100000286 bp) in 2.850 CPU sec, 2.960 real sec...
[M::process] read 187938 sequences (27236582 bp) in 0.760 CPU sec, 0.758 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (15, 286705, 9, 11)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 190, 665)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1703)
[M::mem_pestat] mean and std.dev: (342.64, 373.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2222)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 263, 377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 771)
[M::mem_pestat] mean and std.dev: (288.11, 139.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 968)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (337, 451, 547)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 967)
[M::mem_pestat] mean and std.dev: (463.91, 207.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1295)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 688652 reads in 151.294 CPU sec, 4.816 real sec
[M::mem_process_seqs] Processed 688538 reads in 98.072 CPU sec, 3.119 real sec
sorting block 147, #reads = 1083221 mem = 536880092 peak = 1201004544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (5, 287061, 3, 20)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 264, 378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 774)
[M::mem_pestat] mean and std.dev: (288.80, 140.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 972)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 266, 393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (241.81, 57.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 933)
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (1, 78389, 5, 3)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 257, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (282.61, 137.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 948)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_process_seqs] Processed 688822 reads in 104.826 CPU sec, 3.395 real sec
[M::mem_process_seqs] Processed 187938 reads in 41.118 CPU sec, 1.329 real sec
sorting block 148, #reads = 1082664 mem = 536878464 peak = 1237217280
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 161305078
overall: 69998555136 mem 20988.676 user 198.944 sys 688.967 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.659_bgw-T1-TDNA-1_A23MHWWLT4_1.L004\tPU:L004\tSM:659_bgw-T1-TDNA-1_A23MHWWLT4_1\tLB:659_bgw-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 659_bgw-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 659_bgw-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 688.996 sec; CPU: 21187.623 sec
sorting block 149, #reads = 518429 mem = 257603611 peak = 1237217280
uniq header count 1
merging 150 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31 max 48
algo: util-sort
license: sentieon:util=1
output file size: 8591486837
output reads: 162148260
bam_mem_sort: 150 calls 85.436 user 0.377 sys 87.258 real
bam_write: 150 calls 57.753 user 2.641 sys 89.900 real
execute: 1 calls 45.900 user 0.718 sys 742.011 real
merge_files: 1 calls 45.856 user 0.716 sys 52.392 real
parse_chunk: 2392 calls 103.356 user 24.738 sys 139.091 real
read_chunk: 6456 calls 53.433 user 36.128 sys 660.115 real
sort_block: 1 calls 34.219 user 35.591 sys 634.725 real
write_chunk: 4062 calls 45.481 user 0.474 sys 51.554 real
overall: 3578322944 mem 2100.954 user 76.019 sys 742.026 real
ls: cannot access '*.cram': No such file or directory