Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/b0/9dbd19073ce604330c34c6fff71d63/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/06/ba77a7b57f238eb481a1d342d9f770/1029_BICJ-T1-TDNA-1_A23MHWWLT4_1/1029_BICJ-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta.fai
Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/BWAIndex
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/b0/9dbd19073ce604330c34c6fff71d63/.command.run
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/06/ba77a7b57f238eb481a1d342d9f770/1029_BICJ-T1-TDNA-1_A23MHWWLT4_1/1029_BICJ-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz
==> STAGING COMPLETE (7 inputs)
This software is licensed to bgold@natera.com by Sentieon Inc.
cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1029_BICJ-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 1467.263 CPU sec, 54.361 real sec
[M::process] read 728016 sequences (100000233 bp) in 1.605 CPU sec, 1.607 real sec...
[M::process] read 727774 sequences (100000060 bp) in 1.774 CPU sec, 1.795 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (104, 287299, 63, 108)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (246, 568, 1041)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2631)
[M::mem_pestat] mean and std.dev: (677.19, 532.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3426)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 178, 250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 494)
[M::mem_pestat] mean and std.dev: (195.91, 88.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 616)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 635, 1230)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3372)
[M::mem_pestat] mean and std.dev: (689.53, 686.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4443)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (292, 453, 870)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2026)
[M::mem_pestat] mean and std.dev: (539.11, 418.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2604)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727390 sequences (100000147 bp) in 1.841 CPU sec, 1.845 real sec...
[M::process] read 727832 sequences (100000220 bp) in 1.847 CPU sec, 1.855 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 288113, 64, 123)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 367, 656)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1586)
[M::mem_pestat] mean and std.dev: (421.79, 311.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2051)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 495)
[M::mem_pestat] mean and std.dev: (196.68, 89.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 617)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 543, 2434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6970)
[M::mem_pestat] mean and std.dev: (1254.85, 1499.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9238)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 368, 1017)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2639)
[M::mem_pestat] mean and std.dev: (600.53, 595.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3450)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 728016 reads in 205.688 CPU sec, 6.477 real sec
[M::mem_process_seqs] Processed 727774 reads in 146.042 CPU sec, 4.648 real sec
sorting block 0, #reads = 1079497 mem = 536879075 peak = 602677248
[M::process] read 727288 sequences (100000206 bp) in 2.372 CPU sec, 2.417 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (90, 287722, 87, 89)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 484, 792)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1988)
[M::mem_pestat] mean and std.dev: (568.26, 449.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2586)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 498)
[M::mem_pestat] mean and std.dev: (197.27, 89.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 621)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (298, 561, 1084)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2656)
[M::mem_pestat] mean and std.dev: (723.27, 621.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3442)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 317, 789)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2031)
[M::mem_pestat] mean and std.dev: (511.74, 455.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2652)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728528 sequences (100000232 bp) in 2.000 CPU sec, 1.995 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (101, 288296, 52, 97)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 400, 672)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1536)
[M::mem_pestat] mean and std.dev: (466.01, 336.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1968)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 498)
[M::mem_pestat] mean and std.dev: (197.60, 90.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 621)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 515, 1497)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4197)
[M::mem_pestat] mean and std.dev: (776.98, 759.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5547)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 423, 1230)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3200)
[M::mem_pestat] mean and std.dev: (758.70, 790.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4185)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (93, 288017, 67, 96)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 496, 1217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3303)
[M::mem_pestat] mean and std.dev: (743.36, 741.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4346)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 498)
[M::mem_pestat] mean and std.dev: (197.12, 89.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 621)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 654, 1351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3601)
[M::mem_pestat] mean and std.dev: (682.08, 582.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4726)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (289, 468, 1421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3685)
[M::mem_pestat] mean and std.dev: (802.14, 810.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4817)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 727390 reads in 288.728 CPU sec, 9.219 real sec
sorting block 1, #reads = 1079499 mem = 536881090 peak = 758390784
[M::mem_process_seqs] Processed 727288 reads in 228.026 CPU sec, 7.328 real sec
[M::mem_process_seqs] Processed 727832 reads in 258.443 CPU sec, 8.303 real sec
sorting block 2, #reads = 1080921 mem = 536885433 peak = 758390784
[M::process] read 725956 sequences (100000102 bp) in 2.741 CPU sec, 2.814 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 288865, 53, 105)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 452, 1367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3661)
[M::mem_pestat] mean and std.dev: (643.20, 669.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4808)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 178, 250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 494)
[M::mem_pestat] mean and std.dev: (195.72, 89.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 616)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 415, 958)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2402)
[M::mem_pestat] mean and std.dev: (593.45, 468.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3124)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 462, 880)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2244)
[M::mem_pestat] mean and std.dev: (557.60, 484.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2926)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725228 sequences (100000021 bp) in 2.189 CPU sec, 2.214 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (113, 287237, 79, 102)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (254, 457, 1214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3134)
[M::mem_pestat] mean and std.dev: (643.71, 555.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4094)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 508)
[M::mem_pestat] mean and std.dev: (200.25, 92.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 634)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (268, 501, 1609)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4291)
[M::mem_pestat] mean and std.dev: (912.01, 932.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5632)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 503, 1580)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4246)
[M::mem_pestat] mean and std.dev: (937.56, 1033.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5579)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724140 sequences (100000120 bp) in 1.810 CPU sec, 1.815 real sec...
[M::mem_process_seqs] Processed 728528 reads in 206.325 CPU sec, 6.532 real sec
sorting block 3, #reads = 1080922 mem = 536880080 peak = 770387968
[M::mem_process_seqs] Processed 725956 reads in 145.020 CPU sec, 4.587 real sec
[M::process] read 724668 sequences (100000138 bp) in 2.686 CPU sec, 2.749 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (87, 286944, 69, 102)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 418, 1422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3836)
[M::mem_pestat] mean and std.dev: (853.62, 917.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5043)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 518)
[M::mem_pestat] mean and std.dev: (203.02, 94.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 647)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 419, 1087)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2945)
[M::mem_pestat] mean and std.dev: (685.61, 740.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3874)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 448, 856)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2160)
[M::mem_pestat] mean and std.dev: (536.85, 459.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2812)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724354 sequences (100000108 bp) in 2.160 CPU sec, 2.162 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (90, 287612, 66, 126)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (262, 594, 1319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3433)
[M::mem_pestat] mean and std.dev: (791.02, 721.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4490)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 512)
[M::mem_pestat] mean and std.dev: (201.65, 93.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 639)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 343, 761)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1949)
[M::mem_pestat] mean and std.dev: (412.42, 396.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2543)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 449, 1307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3471)
[M::mem_pestat] mean and std.dev: (754.08, 770.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4553)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724140 reads in 195.103 CPU sec, 6.167 real sec
sorting block 4, #reads = 1079785 mem = 536878534 peak = 770387968
[M::mem_process_seqs] Processed 725228 reads in 224.440 CPU sec, 7.112 real sec
sorting block 5, #reads = 1079117 mem = 536881957 peak = 846860288
[M::process] read 723558 sequences (100000215 bp) in 2.751 CPU sec, 2.838 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (105, 287041, 76, 101)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 363, 1303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3569)
[M::mem_pestat] mean and std.dev: (670.55, 697.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4702)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 518)
[M::mem_pestat] mean and std.dev: (202.70, 94.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 647)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 479, 891)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2391)
[M::mem_pestat] mean and std.dev: (534.29, 533.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3141)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 454, 1887)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5159)
[M::mem_pestat] mean and std.dev: (1040.13, 1075.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6795)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722322 sequences (100000137 bp) in 1.643 CPU sec, 1.645 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (86, 287166, 70, 93)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 375, 932)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2410)
[M::mem_pestat] mean and std.dev: (479.45, 454.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3149)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 518)
[M::mem_pestat] mean and std.dev: (202.55, 93.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 647)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 561, 1151)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3063)
[M::mem_pestat] mean and std.dev: (617.80, 571.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4019)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 715, 2033)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5633)
[M::mem_pestat] mean and std.dev: (1265.59, 1342.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7433)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724668 reads in 199.944 CPU sec, 6.341 real sec
[M::mem_process_seqs] Processed 724354 reads in 228.755 CPU sec, 7.278 real sec
sorting block 6, #reads = 1078869 mem = 536885504 peak = 846860288
[M::process] read 722592 sequences (100000238 bp) in 2.723 CPU sec, 2.828 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (121, 285967, 83, 89)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 329, 884)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2224)
[M::mem_pestat] mean and std.dev: (496.92, 445.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2894)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 186, 264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 526)
[M::mem_pestat] mean and std.dev: (205.71, 95.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 657)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 532, 1194)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3230)
[M::mem_pestat] mean and std.dev: (613.64, 537.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4248)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 447, 1609)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4379)
[M::mem_pestat] mean and std.dev: (768.67, 869.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5764)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720850 sequences (100000021 bp) in 1.900 CPU sec, 1.901 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (103, 286578, 84, 96)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 400, 1072)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2822)
[M::mem_pestat] mean and std.dev: (508.20, 504.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3697)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 184, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 513)
[M::mem_pestat] mean and std.dev: (202.61, 92.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 640)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 552, 1479)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3953)
[M::mem_pestat] mean and std.dev: (757.03, 672.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5190)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 576, 1495)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3983)
[M::mem_pestat] mean and std.dev: (742.51, 766.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5227)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 722322 reads in 198.804 CPU sec, 6.301 real sec
sorting block 7, #reads = 1077332 mem = 536880526 peak = 846860288
[M::mem_process_seqs] Processed 723558 reads in 227.920 CPU sec, 7.243 real sec
[M::process] read 721058 sequences (100000103 bp) in 2.565 CPU sec, 2.664 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (100, 286272, 51, 99)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (253, 493, 1089)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2761)
[M::mem_pestat] mean and std.dev: (602.32, 478.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3597)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 186, 264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 528)
[M::mem_pestat] mean and std.dev: (205.46, 95.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 660)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 466, 1318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3592)
[M::mem_pestat] mean and std.dev: (706.36, 717.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4729)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (285, 607, 1044)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2562)
[M::mem_pestat] mean and std.dev: (731.00, 550.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3321)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721592 sequences (100000063 bp) in 1.700 CPU sec, 1.694 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (102, 285507, 71, 100)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 418, 921)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2381)
[M::mem_pestat] mean and std.dev: (549.97, 519.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3111)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 187, 264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 526)
[M::mem_pestat] mean and std.dev: (206.31, 95.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 657)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 498, 1406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3890)
[M::mem_pestat] mean and std.dev: (576.53, 595.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5132)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 402, 835)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2043)
[M::mem_pestat] mean and std.dev: (520.30, 456.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2647)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 722592 reads in 195.933 CPU sec, 6.219 real sec
sorting block 8, #reads = 1077280 mem = 536880421 peak = 846860288
[M::mem_process_seqs] Processed 720850 reads in 224.348 CPU sec, 7.148 real sec
sorting block 9, #reads = 1075857 mem = 536878550 peak = 900300800
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (95, 285542, 63, 91)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 406, 1144)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3008)
[M::mem_pestat] mean and std.dev: (645.99, 628.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3940)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 187, 264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 526)
[M::mem_pestat] mean and std.dev: (206.15, 95.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 657)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 322, 849)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2277)
[M::mem_pestat] mean and std.dev: (437.18, 451.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2991)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 352, 1108)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2828)
[M::mem_pestat] mean and std.dev: (666.12, 619.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3688)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721748 sequences (100000048 bp) in 2.946 CPU sec, 3.013 real sec...
[M::process] read 721240 sequences (100000224 bp) in 2.189 CPU sec, 2.189 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (119, 285599, 60, 107)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 566, 934)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2300)
[M::mem_pestat] mean and std.dev: (593.29, 417.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2983)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 186, 263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 523)
[M::mem_pestat] mean and std.dev: (205.34, 94.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 653)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 478, 945)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2427)
[M::mem_pestat] mean and std.dev: (562.42, 490.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3168)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 489, 888)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2192)
[M::mem_pestat] mean and std.dev: (625.17, 478.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2844)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 721058 reads in 199.817 CPU sec, 6.320 real sec
[M::mem_process_seqs] Processed 721592 reads in 141.567 CPU sec, 4.495 real sec
sorting block 10, #reads = 1076260 mem = 536882539 peak = 900300800
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (113, 285395, 64, 86)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 553, 1321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3473)
[M::mem_pestat] mean and std.dev: (741.26, 668.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4549)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 187, 264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 526)
[M::mem_pestat] mean and std.dev: (206.04, 94.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 657)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 575, 965)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2527)
[M::mem_pestat] mean and std.dev: (519.79, 404.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3308)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 328, 739)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1779)
[M::mem_pestat] mean and std.dev: (421.41, 336.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2299)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720718 sequences (100000298 bp) in 2.966 CPU sec, 3.138 real sec...
[M::process] read 720716 sequences (100000069 bp) in 2.160 CPU sec, 2.153 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (103, 285573, 66, 99)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 377, 930)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2328)
[M::mem_pestat] mean and std.dev: (553.74, 458.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3027)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 186, 263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 523)
[M::mem_pestat] mean and std.dev: (205.28, 94.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 653)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 451, 1112)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2854)
[M::mem_pestat] mean and std.dev: (602.22, 533.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3725)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 382, 1028)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2668)
[M::mem_pestat] mean and std.dev: (570.20, 524.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3488)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 721240 reads in 200.660 CPU sec, 6.361 real sec
sorting block 11, #reads = 1074576 mem = 536880406 peak = 900300800
[M::mem_process_seqs] Processed 721748 reads in 231.052 CPU sec, 7.355 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (101, 285557, 83, 100)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 430, 823)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2061)
[M::mem_pestat] mean and std.dev: (520.02, 408.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2680)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 188, 265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 527)
[M::mem_pestat] mean and std.dev: (206.53, 94.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 658)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 439, 1712)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4788)
[M::mem_pestat] mean and std.dev: (966.05, 1197.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6326)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 640, 1146)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2962)
[M::mem_pestat] mean and std.dev: (755.83, 669.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3870)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722528 sequences (100000259 bp) in 2.772 CPU sec, 2.848 real sec...
[M::process] read 728480 sequences (100000218 bp) in 2.260 CPU sec, 2.262 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (110, 285594, 63, 104)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (270, 610, 1035)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2565)
[M::mem_pestat] mean and std.dev: (621.05, 436.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3330)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 188, 266)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 530)
[M::mem_pestat] mean and std.dev: (207.43, 95.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 662)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 333, 677)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1715)
[M::mem_pestat] mean and std.dev: (429.36, 401.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2234)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 540, 1094)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2830)
[M::mem_pestat] mean and std.dev: (667.93, 579.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3698)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 720718 reads in 194.770 CPU sec, 6.154 real sec
sorting block 12, #reads = 1075539 mem = 536879621 peak = 900300800
[M::mem_process_seqs] Processed 720716 reads in 139.478 CPU sec, 4.435 real sec
sorting block 13, #reads = 1075202 mem = 536880212 peak = 942125056
[M::process] read 727874 sequences (100000290 bp) in 2.790 CPU sec, 2.859 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (89, 288049, 69, 94)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 476, 1109)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2843)
[M::mem_pestat] mean and std.dev: (576.29, 538.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3710)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 177, 249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 491)
[M::mem_pestat] mean and std.dev: (195.49, 88.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 612)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 516, 987)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2577)
[M::mem_pestat] mean and std.dev: (576.73, 499.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3372)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 403, 857)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2139)
[M::mem_pestat] mean and std.dev: (534.23, 440.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2780)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728102 sequences (100000050 bp) in 2.050 CPU sec, 2.048 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (108, 285780, 54, 110)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 679, 1232)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3242)
[M::mem_pestat] mean and std.dev: (805.85, 710.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4247)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 186, 263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 525)
[M::mem_pestat] mean and std.dev: (205.17, 95.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 656)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (313, 634, 1600)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4174)
[M::mem_pestat] mean and std.dev: (908.13, 797.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5461)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (261, 579, 1559)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4155)
[M::mem_pestat] mean and std.dev: (890.53, 836.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5453)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 728480 reads in 205.061 CPU sec, 6.506 real sec
[M::mem_process_seqs] Processed 722528 reads in 240.265 CPU sec, 7.646 real sec
sorting block 14, #reads = 1078493 mem = 536877047 peak = 942125056
[M::process] read 727564 sequences (100000292 bp) in 2.933 CPU sec, 3.023 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (94, 288518, 63, 101)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 475, 1058)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2798)
[M::mem_pestat] mean and std.dev: (711.61, 676.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3668)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 178, 251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 495)
[M::mem_pestat] mean and std.dev: (196.33, 89.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 617)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (280, 497, 889)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2107)
[M::mem_pestat] mean and std.dev: (527.21, 402.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2716)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 393, 1093)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2793)
[M::mem_pestat] mean and std.dev: (608.01, 524.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3643)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726968 sequences (100000264 bp) in 2.060 CPU sec, 2.055 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (100, 288304, 79, 99)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 481, 765)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1893)
[M::mem_pestat] mean and std.dev: (483.97, 382.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2457)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 178, 251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 497)
[M::mem_pestat] mean and std.dev: (196.94, 90.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 620)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 486, 1099)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3015)
[M::mem_pestat] mean and std.dev: (657.00, 712.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3973)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 376, 966)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2488)
[M::mem_pestat] mean and std.dev: (582.63, 554.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3249)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 727874 reads in 202.063 CPU sec, 6.398 real sec
sorting block 15, #reads = 1077103 mem = 536878403 peak = 942125056
[M::process] read 726780 sequences (100000070 bp) in 2.723 CPU sec, 2.731 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (101, 287743, 62, 115)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 508, 904)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2390)
[M::mem_pestat] mean and std.dev: (544.40, 460.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3133)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 180, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 504)
[M::mem_pestat] mean and std.dev: (198.73, 91.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 629)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 432, 1186)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3138)
[M::mem_pestat] mean and std.dev: (686.32, 692.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4114)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 441, 1682)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4546)
[M::mem_pestat] mean and std.dev: (919.57, 1033.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5978)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 726968 reads in 116.801 CPU sec, 3.688 real sec
[M::mem_process_seqs] Processed 728102 reads in 286.193 CPU sec, 9.107 real sec
sorting block 16, #reads = 1080351 mem = 536882226 peak = 942125056
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (99, 288103, 73, 85)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 491, 1281)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3441)
[M::mem_pestat] mean and std.dev: (810.93, 752.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4521)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 501)
[M::mem_pestat] mean and std.dev: (198.01, 90.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 625)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 556, 1034)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2724)
[M::mem_pestat] mean and std.dev: (637.00, 562.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3569)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 376, 756)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1800)
[M::mem_pestat] mean and std.dev: (452.12, 356.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2322)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726504 sequences (100000081 bp) in 2.731 CPU sec, 2.812 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (83, 287966, 62, 104)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 354, 1009)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2563)
[M::mem_pestat] mean and std.dev: (562.68, 526.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3340)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 180, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 504)
[M::mem_pestat] mean and std.dev: (198.86, 91.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 629)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 398, 889)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2245)
[M::mem_pestat] mean and std.dev: (424.09, 366.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2923)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 353, 835)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2109)
[M::mem_pestat] mean and std.dev: (530.15, 484.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2746)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725350 sequences (100000010 bp) in 2.240 CPU sec, 2.242 real sec...
[M::mem_process_seqs] Processed 727564 reads in 317.855 CPU sec, 10.044 real sec
sorting block 17, #reads = 1082838 mem = 536880026 peak = 942125056
[M::mem_process_seqs] Processed 726780 reads in 143.014 CPU sec, 4.527 real sec
sorting block 18, #reads = 1081356 mem = 536883494 peak = 942125056
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (86, 288085, 70, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 279, 752)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1860)
[M::mem_pestat] mean and std.dev: (463.98, 384.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2414)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 180, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 508)
[M::mem_pestat] mean and std.dev: (199.64, 92.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 634)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 412, 1358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3712)
[M::mem_pestat] mean and std.dev: (605.45, 645.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4889)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 534, 948)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2378)
[M::mem_pestat] mean and std.dev: (638.07, 504.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3093)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724918 sequences (100000079 bp) in 3.097 CPU sec, 3.170 real sec...
[M::process] read 724504 sequences (100000286 bp) in 2.180 CPU sec, 2.182 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (93, 287525, 55, 111)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 335, 1041)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2709)
[M::mem_pestat] mean and std.dev: (630.85, 634.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3543)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 182, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 517)
[M::mem_pestat] mean and std.dev: (201.89, 94.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 646)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (257, 701, 1856)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5054)
[M::mem_pestat] mean and std.dev: (1091.93, 1134.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6653)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 415, 788)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1866)
[M::mem_pestat] mean and std.dev: (514.81, 387.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2405)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 726504 reads in 200.942 CPU sec, 6.360 real sec
[M::mem_process_seqs] Processed 725350 reads in 141.720 CPU sec, 4.497 real sec
sorting block 19, #reads = 1079673 mem = 536883752 peak = 942125056
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (89, 287214, 62, 99)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 435, 940)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2360)
[M::mem_pestat] mean and std.dev: (603.09, 519.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3070)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 518)
[M::mem_pestat] mean and std.dev: (202.76, 94.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 647)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 465, 1514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4150)
[M::mem_pestat] mean and std.dev: (846.87, 907.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5468)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 296, 872)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2200)
[M::mem_pestat] mean and std.dev: (468.79, 470.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2864)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724138 sequences (100000225 bp) in 2.559 CPU sec, 2.654 real sec...
[M::process] read 722804 sequences (100000299 bp) in 1.880 CPU sec, 1.880 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (96, 287019, 76, 87)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 378, 747)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1875)
[M::mem_pestat] mean and std.dev: (460.42, 408.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2439)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 518)
[M::mem_pestat] mean and std.dev: (202.86, 94.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 647)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 563, 986)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2558)
[M::mem_pestat] mean and std.dev: (578.79, 471.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3344)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (333, 543, 1442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3660)
[M::mem_pestat] mean and std.dev: (738.55, 722.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4769)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724918 reads in 201.585 CPU sec, 6.399 real sec
sorting block 20, #reads = 1081086 mem = 536885973 peak = 942125056
[M::mem_process_seqs] Processed 724504 reads in 143.737 CPU sec, 4.586 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (102, 286446, 85, 93)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 330, 740)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1782)
[M::mem_pestat] mean and std.dev: (431.20, 325.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2303)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 525)
[M::mem_pestat] mean and std.dev: (205.05, 95.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 656)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (307, 604, 1482)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3832)
[M::mem_pestat] mean and std.dev: (757.49, 718.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5007)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (301, 444, 1152)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2854)
[M::mem_pestat] mean and std.dev: (674.76, 553.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3705)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722256 sequences (100000185 bp) in 3.113 CPU sec, 3.170 real sec...
[M::process] read 722226 sequences (100000113 bp) in 2.340 CPU sec, 2.335 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (107, 286606, 88, 100)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (295, 488, 1094)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2692)
[M::mem_pestat] mean and std.dev: (648.47, 477.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3491)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 521)
[M::mem_pestat] mean and std.dev: (203.52, 94.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 651)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (94, 396, 903)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2521)
[M::mem_pestat] mean and std.dev: (573.76, 581.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3330)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 434, 1182)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3086)
[M::mem_pestat] mean and std.dev: (688.44, 652.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4038)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 722804 reads in 205.846 CPU sec, 6.508 real sec
sorting block 21, #reads = 1077896 mem = 536879280 peak = 942125056
[M::mem_process_seqs] Processed 724138 reads in 236.374 CPU sec, 7.511 real sec
sorting block 22, #reads = 1078683 mem = 536880061 peak = 942125056
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (110, 286664, 78, 110)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 609, 1135)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2987)
[M::mem_pestat] mean and std.dev: (685.49, 575.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3913)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 186, 265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 529)
[M::mem_pestat] mean and std.dev: (206.46, 96.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 661)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 514, 1499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4177)
[M::mem_pestat] mean and std.dev: (768.74, 802.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5516)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 447, 867)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2179)
[M::mem_pestat] mean and std.dev: (582.03, 501.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2835)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721564 sequences (100000094 bp) in 2.936 CPU sec, 3.029 real sec...
[M::process] read 721214 sequences (100000151 bp) in 2.340 CPU sec, 2.339 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (110, 286933, 63, 107)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 573, 851)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2051)
[M::mem_pestat] mean and std.dev: (580.12, 446.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2651)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 186, 264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 526)
[M::mem_pestat] mean and std.dev: (205.67, 95.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 657)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (382, 666, 1098)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2530)
[M::mem_pestat] mean and std.dev: (710.68, 519.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3246)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 346, 809)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1949)
[M::mem_pestat] mean and std.dev: (497.90, 458.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2519)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 722256 reads in 208.638 CPU sec, 6.600 real sec
[M::mem_process_seqs] Processed 722226 reads in 149.150 CPU sec, 4.738 real sec
sorting block 23, #reads = 1077862 mem = 536883941 peak = 942125056
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (102, 285857, 101, 92)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 498, 1291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3423)
[M::mem_pestat] mean and std.dev: (786.91, 754.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4489)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 187, 266)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 532)
[M::mem_pestat] mean and std.dev: (206.83, 95.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 665)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (332, 723, 1508)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3860)
[M::mem_pestat] mean and std.dev: (975.51, 865.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5036)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 431, 1153)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3063)
[M::mem_pestat] mean and std.dev: (666.41, 641.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4018)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721770 sequences (100000062 bp) in 3.310 CPU sec, 3.396 real sec...
[M::process] read 721776 sequences (100000098 bp) in 2.409 CPU sec, 2.419 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (89, 286045, 66, 99)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 547, 1067)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2715)
[M::mem_pestat] mean and std.dev: (648.06, 543.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3539)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 187, 265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 529)
[M::mem_pestat] mean and std.dev: (206.67, 95.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 661)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 647, 1016)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2506)
[M::mem_pestat] mean and std.dev: (634.31, 525.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3251)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (267, 602, 1544)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4098)
[M::mem_pestat] mean and std.dev: (936.33, 999.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5375)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 721214 reads in 215.083 CPU sec, 6.807 real sec
sorting block 24, #reads = 1077363 mem = 536880673 peak = 942125056
[M::mem_process_seqs] Processed 721564 reads in 245.946 CPU sec, 7.814 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (113, 285361, 85, 98)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 659, 1482)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4000)
[M::mem_pestat] mean and std.dev: (889.63, 795.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5259)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 186, 263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 523)
[M::mem_pestat] mean and std.dev: (205.21, 94.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 653)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 514, 1192)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3138)
[M::mem_pestat] mean and std.dev: (723.28, 686.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4111)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 368, 942)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2458)
[M::mem_pestat] mean and std.dev: (564.07, 548.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3216)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722068 sequences (100000146 bp) in 3.034 CPU sec, 3.137 real sec...
[M::process] read 721350 sequences (100000207 bp) in 2.079 CPU sec, 2.087 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (103, 286209, 70, 138)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 519, 1402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3798)
[M::mem_pestat] mean and std.dev: (775.86, 853.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4996)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 186, 263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 523)
[M::mem_pestat] mean and std.dev: (205.29, 94.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 653)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (81, 512, 1353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3897)
[M::mem_pestat] mean and std.dev: (692.51, 761.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5169)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (259, 428, 968)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2386)
[M::mem_pestat] mean and std.dev: (533.71, 422.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3095)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 721770 reads in 215.519 CPU sec, 6.840 real sec
sorting block 25, #reads = 1077098 mem = 536879093 peak = 942125056
[M::mem_process_seqs] Processed 721776 reads in 151.214 CPU sec, 4.833 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (84, 285527, 64, 113)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 446, 986)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2462)
[M::mem_pestat] mean and std.dev: (576.67, 489.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3200)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 186, 263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 523)
[M::mem_pestat] mean and std.dev: (204.96, 94.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 653)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (505, 1025, 1606)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3808)
[M::mem_pestat] mean and std.dev: (923.48, 725.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4909)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 346, 1100)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2946)
[M::mem_pestat] mean and std.dev: (548.75, 523.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3869)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 26, #reads = 1074697 mem = 536883115 peak = 942125056
[M::process] read 722102 sequences (100000194 bp) in 3.752 CPU sec, 3.896 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (90, 285543, 66, 106)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 479, 1153)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3063)
[M::mem_pestat] mean and std.dev: (732.85, 672.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4018)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 187, 264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 526)
[M::mem_pestat] mean and std.dev: (205.97, 95.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 657)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 359, 610)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1498)
[M::mem_pestat] mean and std.dev: (381.95, 311.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1942)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 378, 836)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2154)
[M::mem_pestat] mean and std.dev: (489.66, 419.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2813)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724744 sequences (100000165 bp) in 2.630 CPU sec, 2.629 real sec...
[M::mem_process_seqs] Processed 722068 reads in 221.588 CPU sec, 7.031 real sec
[M::mem_process_seqs] Processed 721350 reads in 168.543 CPU sec, 5.371 real sec
sorting block 27, #reads = 1076262 mem = 536880049 peak = 942125056
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (84, 285997, 59, 85)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 550, 1352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3672)
[M::mem_pestat] mean and std.dev: (777.10, 719.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4832)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 186, 263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 525)
[M::mem_pestat] mean and std.dev: (205.19, 95.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 656)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (246, 616, 1961)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5391)
[M::mem_pestat] mean and std.dev: (905.91, 982.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7106)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 382, 816)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2038)
[M::mem_pestat] mean and std.dev: (463.18, 342.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2649)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 729356 sequences (100000221 bp) in 3.620 CPU sec, 3.785 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (109, 286633, 54, 101)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 416, 1014)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2604)
[M::mem_pestat] mean and std.dev: (643.56, 652.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3399)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 512)
[M::mem_pestat] mean and std.dev: (201.53, 92.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 639)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (272, 807, 1507)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3977)
[M::mem_pestat] mean and std.dev: (905.20, 772.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5212)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (267, 491, 992)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2442)
[M::mem_pestat] mean and std.dev: (597.47, 483.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3167)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728068 sequences (100000054 bp) in 2.610 CPU sec, 2.606 real sec...
[M::mem_process_seqs] Processed 722102 reads in 223.889 CPU sec, 7.101 real sec
sorting block 28, #reads = 1075400 mem = 536876361 peak = 942125056
[M::mem_process_seqs] Processed 724744 reads in 159.667 CPU sec, 5.059 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (93, 288417, 66, 88)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 301, 709)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1777)
[M::mem_pestat] mean and std.dev: (413.98, 391.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2311)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 177, 249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 491)
[M::mem_pestat] mean and std.dev: (194.91, 88.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 612)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 589, 1176)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3248)
[M::mem_pestat] mean and std.dev: (750.75, 642.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4284)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (268, 426, 1090)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2734)
[M::mem_pestat] mean and std.dev: (651.98, 615.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3556)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727852 sequences (100000142 bp) in 3.514 CPU sec, 3.627 real sec...
[M::process] read 727796 sequences (100000055 bp) in 2.108 CPU sec, 2.111 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (86, 288272, 60, 89)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 450, 1112)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2902)
[M::mem_pestat] mean and std.dev: (610.33, 563.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3797)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 178, 250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 492)
[M::mem_pestat] mean and std.dev: (196.15, 89.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 613)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (322, 605, 1140)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2776)
[M::mem_pestat] mean and std.dev: (682.91, 560.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3594)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 504, 1048)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2672)
[M::mem_pestat] mean and std.dev: (638.62, 498.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3484)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 729356 reads in 219.628 CPU sec, 6.976 real sec
sorting block 29, #reads = 1077014 mem = 536876223 peak = 942125056
[M::mem_process_seqs] Processed 728068 reads in 252.295 CPU sec, 8.047 real sec
sorting block 30, #reads = 1080165 mem = 536877174 peak = 996175872
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 288155, 60, 109)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 371, 1018)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2718)
[M::mem_pestat] mean and std.dev: (547.11, 499.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3568)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 501)
[M::mem_pestat] mean and std.dev: (197.71, 90.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 625)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (279, 620, 1342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3468)
[M::mem_pestat] mean and std.dev: (804.77, 721.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4531)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 395, 804)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2028)
[M::mem_pestat] mean and std.dev: (508.23, 389.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2640)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726814 sequences (100000170 bp) in 3.065 CPU sec, 3.161 real sec...
[M::process] read 726602 sequences (100000008 bp) in 2.140 CPU sec, 2.159 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (86, 288335, 66, 124)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 404, 917)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2381)
[M::mem_pestat] mean and std.dev: (554.48, 529.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3113)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 504)
[M::mem_pestat] mean and std.dev: (198.31, 91.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 629)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 769, 1666)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4536)
[M::mem_pestat] mean and std.dev: (877.25, 854.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5971)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 591, 1203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3175)
[M::mem_pestat] mean and std.dev: (711.15, 597.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4161)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 727852 reads in 222.543 CPU sec, 7.070 real sec
[M::mem_process_seqs] Processed 727796 reads in 157.737 CPU sec, 5.023 real sec
sorting block 31, #reads = 1079409 mem = 536878203 peak = 996175872
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 288255, 82, 84)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 818, 1241)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3311)
[M::mem_pestat] mean and std.dev: (954.73, 938.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4708)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 180, 255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 507)
[M::mem_pestat] mean and std.dev: (199.26, 92.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 633)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (98, 651, 1455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4169)
[M::mem_pestat] mean and std.dev: (958.49, 1054.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5526)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 363, 848)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2072)
[M::mem_pestat] mean and std.dev: (485.17, 372.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2684)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726078 sequences (100000142 bp) in 3.137 CPU sec, 3.219 real sec...
[M::process] read 725136 sequences (100000238 bp) in 2.310 CPU sec, 2.312 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (112, 288101, 62, 100)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (266, 392, 1388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3632)
[M::mem_pestat] mean and std.dev: (723.98, 748.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4754)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 508)
[M::mem_pestat] mean and std.dev: (200.00, 92.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 634)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 574, 1338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3682)
[M::mem_pestat] mean and std.dev: (777.76, 769.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4854)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 418, 1012)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2542)
[M::mem_pestat] mean and std.dev: (573.16, 504.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3307)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 726814 reads in 220.936 CPU sec, 7.009 real sec
sorting block 32, #reads = 1079539 mem = 536879386 peak = 996175872
[M::mem_process_seqs] Processed 726602 reads in 154.527 CPU sec, 4.923 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (100, 287578, 61, 95)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 359, 1051)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2713)
[M::mem_pestat] mean and std.dev: (598.30, 634.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3544)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 511)
[M::mem_pestat] mean and std.dev: (200.59, 93.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 638)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (320, 516, 1587)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4121)
[M::mem_pestat] mean and std.dev: (899.93, 903.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5388)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 430, 760)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1868)
[M::mem_pestat] mean and std.dev: (521.78, 412.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2422)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724930 sequences (100000218 bp) in 2.933 CPU sec, 3.017 real sec...
[M::process] read 725116 sequences (100000111 bp) in 2.380 CPU sec, 2.377 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (110, 287395, 69, 90)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 339, 1246)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3314)
[M::mem_pestat] mean and std.dev: (627.26, 609.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4348)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 183, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 517)
[M::mem_pestat] mean and std.dev: (202.22, 94.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 646)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 536, 929)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2469)
[M::mem_pestat] mean and std.dev: (530.69, 425.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3239)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (268, 527, 1074)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2686)
[M::mem_pestat] mean and std.dev: (795.80, 732.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3726)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 726078 reads in 217.233 CPU sec, 7.154 real sec
sorting block 33, #reads = 1080728 mem = 536884341 peak = 996175872
[M::mem_process_seqs] Processed 725136 reads in 152.028 CPU sec, 4.836 real sec
sorting block 34, #reads = 1078403 mem = 536879376 peak = 996175872
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (105, 286541, 105, 118)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 385, 870)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2160)
[M::mem_pestat] mean and std.dev: (502.88, 394.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2805)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 515)
[M::mem_pestat] mean and std.dev: (202.15, 94.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 643)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (269, 602, 1471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3875)
[M::mem_pestat] mean and std.dev: (681.69, 588.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5077)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 451, 1023)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2669)
[M::mem_pestat] mean and std.dev: (580.00, 513.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3492)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724158 sequences (100000265 bp) in 2.968 CPU sec, 3.009 real sec...
[M::process] read 723934 sequences (100000065 bp) in 2.396 CPU sec, 2.395 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (100, 287151, 44, 114)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (258, 515, 869)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2091)
[M::mem_pestat] mean and std.dev: (522.42, 398.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2702)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 182, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 517)
[M::mem_pestat] mean and std.dev: (201.68, 93.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 646)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (258, 653, 1584)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4236)
[M::mem_pestat] mean and std.dev: (902.59, 958.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5562)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 371, 895)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2297)
[M::mem_pestat] mean and std.dev: (519.05, 447.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2998)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724930 reads in 216.335 CPU sec, 6.853 real sec
sorting block 35, #reads = 1079097 mem = 536891479 peak = 996175872
[M::mem_process_seqs] Processed 725116 reads in 153.354 CPU sec, 4.876 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (101, 286655, 62, 108)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 518, 1120)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2912)
[M::mem_pestat] mean and std.dev: (683.54, 676.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3808)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 518)
[M::mem_pestat] mean and std.dev: (202.78, 93.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 647)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 512, 909)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2351)
[M::mem_pestat] mean and std.dev: (572.05, 488.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3072)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (292, 537, 1376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3544)
[M::mem_pestat] mean and std.dev: (829.20, 798.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4628)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723966 sequences (100000125 bp) in 3.404 CPU sec, 3.588 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (114, 287405, 88, 92)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 490, 961)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2467)
[M::mem_pestat] mean and std.dev: (635.72, 513.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3220)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 521)
[M::mem_pestat] mean and std.dev: (203.69, 95.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 651)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 512, 1583)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4337)
[M::mem_pestat] mean and std.dev: (682.18, 667.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5714)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 446, 1393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3713)
[M::mem_pestat] mean and std.dev: (766.69, 803.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4873)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723436 sequences (100000110 bp) in 2.092 CPU sec, 2.107 real sec...
[M::mem_process_seqs] Processed 723934 reads in 214.090 CPU sec, 6.787 real sec
sorting block 36, #reads = 1078464 mem = 536878653 peak = 996175872
[M::mem_process_seqs] Processed 724158 reads in 246.283 CPU sec, 7.833 real sec
sorting block 37, #reads = 1078550 mem = 536878337 peak = 996175872
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (106, 285912, 81, 106)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 425, 930)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2318)
[M::mem_pestat] mean and std.dev: (522.26, 460.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3012)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 518)
[M::mem_pestat] mean and std.dev: (202.87, 94.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 647)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 491, 1119)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2981)
[M::mem_pestat] mean and std.dev: (603.54, 567.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3912)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (291, 431, 823)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1887)
[M::mem_pestat] mean and std.dev: (513.57, 343.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2419)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723090 sequences (100000004 bp) in 3.291 CPU sec, 3.363 real sec...
[M::process] read 723464 sequences (100000071 bp) in 2.137 CPU sec, 2.144 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (91, 286331, 71, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 496, 955)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2393)
[M::mem_pestat] mean and std.dev: (634.18, 509.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3112)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 184, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 513)
[M::mem_pestat] mean and std.dev: (202.52, 93.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 640)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (365, 516, 1575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3995)
[M::mem_pestat] mean and std.dev: (835.14, 863.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5205)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 438, 1827)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5019)
[M::mem_pestat] mean and std.dev: (1085.12, 1318.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6615)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723966 reads in 211.435 CPU sec, 6.692 real sec
[M::mem_process_seqs] Processed 723436 reads in 242.154 CPU sec, 7.699 real sec
sorting block 38, #reads = 1077471 mem = 536878778 peak = 996175872
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (102, 286091, 91, 95)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 314, 865)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2253)
[M::mem_pestat] mean and std.dev: (470.47, 460.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2947)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 184, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 516)
[M::mem_pestat] mean and std.dev: (202.71, 92.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 644)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (319, 630, 1347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3403)
[M::mem_pestat] mean and std.dev: (898.70, 825.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4431)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 350, 746)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1764)
[M::mem_pestat] mean and std.dev: (466.25, 370.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2273)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723296 sequences (100000195 bp) in 2.876 CPU sec, 2.950 real sec...
[M::process] read 722260 sequences (100000285 bp) in 1.945 CPU sec, 1.948 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (92, 286269, 75, 125)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (252, 536, 1146)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2934)
[M::mem_pestat] mean and std.dev: (634.31, 529.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3828)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 184, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 513)
[M::mem_pestat] mean and std.dev: (202.59, 93.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 640)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (346, 559, 1268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3112)
[M::mem_pestat] mean and std.dev: (635.73, 577.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4034)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 333, 898)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2204)
[M::mem_pestat] mean and std.dev: (480.71, 394.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2857)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723090 reads in 215.053 CPU sec, 6.832 real sec
[M::mem_process_seqs] Processed 723464 reads in 152.934 CPU sec, 4.881 real sec
sorting block 39, #reads = 1075040 mem = 536878389 peak = 996175872
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (94, 286357, 51, 90)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 378, 1002)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2568)
[M::mem_pestat] mean and std.dev: (681.58, 668.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3356)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 184, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 516)
[M::mem_pestat] mean and std.dev: (203.29, 93.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 644)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 564, 1454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3904)
[M::mem_pestat] mean and std.dev: (894.30, 983.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5129)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (264, 482, 1046)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2610)
[M::mem_pestat] mean and std.dev: (633.89, 580.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3392)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722538 sequences (100000204 bp) in 3.031 CPU sec, 3.103 real sec...
[M::process] read 722266 sequences (100000134 bp) in 2.440 CPU sec, 2.474 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (117, 285984, 72, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 376, 1031)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2693)
[M::mem_pestat] mean and std.dev: (553.94, 536.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3524)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 522)
[M::mem_pestat] mean and std.dev: (204.56, 94.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 652)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 561, 1267)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3307)
[M::mem_pestat] mean and std.dev: (757.10, 782.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4327)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 362, 862)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2172)
[M::mem_pestat] mean and std.dev: (490.38, 407.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2827)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723296 reads in 212.643 CPU sec, 6.750 real sec
sorting block 40, #reads = 1076479 mem = 536881040 peak = 996175872
[M::mem_process_seqs] Processed 722260 reads in 148.192 CPU sec, 4.792 real sec
sorting block 41, #reads = 1076598 mem = 536881941 peak = 996175872
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (97, 286549, 73, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 626, 1333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3503)
[M::mem_pestat] mean and std.dev: (844.63, 757.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4588)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 522)
[M::mem_pestat] mean and std.dev: (204.41, 94.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 652)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 537, 998)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2452)
[M::mem_pestat] mean and std.dev: (658.10, 528.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3179)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 465, 917)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2393)
[M::mem_pestat] mean and std.dev: (568.61, 477.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3131)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722196 sequences (100000084 bp) in 2.839 CPU sec, 2.898 real sec...
[M::process] read 727136 sequences (100000097 bp) in 2.256 CPU sec, 2.256 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (104, 286295, 71, 95)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 513, 992)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2540)
[M::mem_pestat] mean and std.dev: (588.76, 464.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3314)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 186, 262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 522)
[M::mem_pestat] mean and std.dev: (204.75, 94.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 652)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 744, 1244)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3322)
[M::mem_pestat] mean and std.dev: (844.55, 771.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4361)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 489, 907)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2265)
[M::mem_pestat] mean and std.dev: (596.67, 496.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2944)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 722538 reads in 211.177 CPU sec, 6.776 real sec
[M::mem_process_seqs] Processed 722266 reads in 152.274 CPU sec, 4.852 real sec
sorting block 42, #reads = 1075968 mem = 536880157 peak = 996175872
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (123, 286179, 64, 111)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 394, 1106)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2896)
[M::mem_pestat] mean and std.dev: (627.50, 558.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3791)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 186, 263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 523)
[M::mem_pestat] mean and std.dev: (205.28, 94.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 653)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 794, 1340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3478)
[M::mem_pestat] mean and std.dev: (908.79, 854.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4547)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 352, 899)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2305)
[M::mem_pestat] mean and std.dev: (542.02, 540.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3008)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728584 sequences (100000003 bp) in 2.812 CPU sec, 2.853 real sec...
[M::process] read 728356 sequences (100000297 bp) in 2.407 CPU sec, 2.410 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 287464, 82, 96)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 282, 688)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1756)
[M::mem_pestat] mean and std.dev: (353.11, 330.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2290)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 501)
[M::mem_pestat] mean and std.dev: (197.88, 90.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 625)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 649, 989)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2639)
[M::mem_pestat] mean and std.dev: (629.88, 524.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3464)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 375, 1379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3629)
[M::mem_pestat] mean and std.dev: (707.95, 758.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4754)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 722196 reads in 211.031 CPU sec, 6.680 real sec
sorting block 43, #reads = 1076843 mem = 536881787 peak = 996175872
[M::mem_process_seqs] Processed 727136 reads in 152.638 CPU sec, 4.853 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (96, 288592, 70, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 380, 1008)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2656)
[M::mem_pestat] mean and std.dev: (602.19, 573.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3480)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 178, 252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 500)
[M::mem_pestat] mean and std.dev: (197.09, 90.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 624)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (259, 616, 1601)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4285)
[M::mem_pestat] mean and std.dev: (1071.84, 1066.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5627)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 358, 902)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2288)
[M::mem_pestat] mean and std.dev: (558.70, 512.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2981)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727298 sequences (100000245 bp) in 3.179 CPU sec, 3.209 real sec...
[M::process] read 726870 sequences (100000112 bp) in 2.359 CPU sec, 2.363 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (102, 288020, 60, 116)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 470, 795)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1939)
[M::mem_pestat] mean and std.dev: (513.25, 420.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2511)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 178, 250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 494)
[M::mem_pestat] mean and std.dev: (196.20, 89.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 616)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 463, 1181)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3157)
[M::mem_pestat] mean and std.dev: (580.82, 608.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4145)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 711, 1985)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5503)
[M::mem_pestat] mean and std.dev: (1110.30, 1164.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7262)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 728356 reads in 203.475 CPU sec, 6.431 real sec
sorting block 44, #reads = 1077593 mem = 536881062 peak = 996175872
[M::mem_process_seqs] Processed 728584 reads in 233.264 CPU sec, 7.404 real sec
sorting block 45, #reads = 1080440 mem = 536880325 peak = 996175872
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (96, 287750, 49, 93)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 440, 1084)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2870)
[M::mem_pestat] mean and std.dev: (679.60, 590.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3763)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 504)
[M::mem_pestat] mean and std.dev: (198.38, 91.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 629)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (123, 374, 975)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2679)
[M::mem_pestat] mean and std.dev: (490.51, 477.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3531)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 572, 1227)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3191)
[M::mem_pestat] mean and std.dev: (765.41, 714.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4173)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726086 sequences (100000147 bp) in 2.555 CPU sec, 2.617 real sec...
[M::process] read 725966 sequences (100000127 bp) in 2.200 CPU sec, 2.198 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (100, 287962, 70, 85)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 642, 1252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3276)
[M::mem_pestat] mean and std.dev: (771.88, 705.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4288)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 180, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 504)
[M::mem_pestat] mean and std.dev: (198.57, 91.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 629)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (433, 780, 1472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3550)
[M::mem_pestat] mean and std.dev: (858.72, 663.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4589)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 334, 795)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1985)
[M::mem_pestat] mean and std.dev: (464.67, 392.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2580)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 727298 reads in 202.248 CPU sec, 6.411 real sec
[M::mem_process_seqs] Processed 726870 reads in 148.489 CPU sec, 4.732 real sec
sorting block 46, #reads = 1079762 mem = 536880292 peak = 996175872
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (99, 288240, 61, 104)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 440, 832)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2164)
[M::mem_pestat] mean and std.dev: (529.98, 485.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2830)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 511)
[M::mem_pestat] mean and std.dev: (200.39, 92.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 638)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (266, 407, 1040)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2588)
[M::mem_pestat] mean and std.dev: (612.45, 550.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3362)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 403, 937)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2427)
[M::mem_pestat] mean and std.dev: (514.92, 479.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3172)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726036 sequences (100000024 bp) in 3.244 CPU sec, 3.351 real sec...
[M::process] read 725340 sequences (100000083 bp) in 2.059 CPU sec, 2.064 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (100, 287688, 53, 94)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 399, 825)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2047)
[M::mem_pestat] mean and std.dev: (494.85, 384.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2658)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 511)
[M::mem_pestat] mean and std.dev: (200.53, 92.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 638)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 616, 1974)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5544)
[M::mem_pestat] mean and std.dev: (966.50, 1061.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7329)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 557, 1162)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2996)
[M::mem_pestat] mean and std.dev: (784.67, 707.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3913)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 726086 reads in 208.755 CPU sec, 6.626 real sec
sorting block 47, #reads = 1080387 mem = 536878463 peak = 996175872
[M::mem_process_seqs] Processed 725966 reads in 239.007 CPU sec, 7.610 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (93, 288069, 60, 104)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 442, 1054)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2778)
[M::mem_pestat] mean and std.dev: (593.00, 612.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3640)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 511)
[M::mem_pestat] mean and std.dev: (200.72, 93.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 638)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 520, 1102)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2906)
[M::mem_pestat] mean and std.dev: (704.60, 643.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3808)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 507, 1469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4023)
[M::mem_pestat] mean and std.dev: (710.62, 625.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5300)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725216 sequences (100000028 bp) in 2.874 CPU sec, 2.991 real sec...
[M::process] read 724802 sequences (100000093 bp) in 2.207 CPU sec, 2.211 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (97, 286912, 69, 94)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 286, 789)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2025)
[M::mem_pestat] mean and std.dev: (473.77, 427.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2643)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 182, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 514)
[M::mem_pestat] mean and std.dev: (201.52, 93.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 642)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (289, 906, 1907)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5143)
[M::mem_pestat] mean and std.dev: (898.00, 865.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6761)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 431, 1117)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2887)
[M::mem_pestat] mean and std.dev: (696.28, 684.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3772)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 726036 reads in 204.198 CPU sec, 6.476 real sec
sorting block 48, #reads = 1079674 mem = 536880220 peak = 996175872
[M::mem_process_seqs] Processed 725340 reads in 148.823 CPU sec, 4.734 real sec
sorting block 49, #reads = 1079606 mem = 536879872 peak = 996175872
[M::process] read 725022 sequences (100000274 bp) in 2.583 CPU sec, 2.614 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (108, 287034, 80, 108)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 467, 1086)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2894)
[M::mem_pestat] mean and std.dev: (574.19, 542.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3798)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 182, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 511)
[M::mem_pestat] mean and std.dev: (200.76, 92.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 638)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 514, 1000)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2560)
[M::mem_pestat] mean and std.dev: (650.62, 609.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3340)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 380, 1131)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2959)
[M::mem_pestat] mean and std.dev: (614.80, 541.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3873)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724878 sequences (100000241 bp) in 2.050 CPU sec, 2.054 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (97, 287080, 60, 81)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 453, 973)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2439)
[M::mem_pestat] mean and std.dev: (581.71, 534.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3172)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 182, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 512)
[M::mem_pestat] mean and std.dev: (201.59, 93.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 639)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (315, 656, 1128)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2754)
[M::mem_pestat] mean and std.dev: (699.08, 600.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3567)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (260, 448, 1168)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2984)
[M::mem_pestat] mean and std.dev: (785.08, 759.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3892)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (98, 287040, 67, 98)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 443, 1315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3457)
[M::mem_pestat] mean and std.dev: (734.67, 692.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4528)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 182, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 512)
[M::mem_pestat] mean and std.dev: (201.30, 92.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 639)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 568, 1435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3815)
[M::mem_pestat] mean and std.dev: (794.52, 881.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5005)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 450, 1126)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2880)
[M::mem_pestat] mean and std.dev: (766.60, 762.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3815)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 725216 reads in 291.373 CPU sec, 9.305 real sec
[M::mem_process_seqs] Processed 724802 reads in 231.379 CPU sec, 7.432 real sec
sorting block 50, #reads = 1079170 mem = 536876948 peak = 996175872
[M::mem_process_seqs] Processed 725022 reads in 261.316 CPU sec, 8.402 real sec
[M::process] read 724956 sequences (100000248 bp) in 2.963 CPU sec, 3.049 real sec...
sorting block 51, #reads = 1078542 mem = 536877349 peak = 996175872
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (110, 287417, 62, 84)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 417, 1027)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2683)
[M::mem_pestat] mean and std.dev: (662.14, 666.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3511)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 182, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 506)
[M::mem_pestat] mean and std.dev: (200.33, 91.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 631)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 666, 1332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3716)
[M::mem_pestat] mean and std.dev: (785.07, 813.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4908)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 530, 1495)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4013)
[M::mem_pestat] mean and std.dev: (790.43, 756.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5272)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725424 sequences (100000148 bp) in 2.616 CPU sec, 2.662 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (102, 286270, 67, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 494, 822)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2064)
[M::mem_pestat] mean and std.dev: (554.08, 450.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2685)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 505)
[M::mem_pestat] mean and std.dev: (199.70, 91.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 630)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (132, 315, 805)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2151)
[M::mem_pestat] mean and std.dev: (422.48, 395.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2824)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 315, 685)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1651)
[M::mem_pestat] mean and std.dev: (462.63, 351.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2134)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724878 reads in 208.410 CPU sec, 6.602 real sec
[M::process] read 725108 sequences (100000259 bp) in 2.452 CPU sec, 2.465 real sec...
[M::mem_process_seqs] Processed 724956 reads in 150.840 CPU sec, 4.756 real sec
sorting block 52, #reads = 1079222 mem = 536880207 peak = 996175872
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (123, 286924, 77, 84)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 452, 774)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1866)
[M::mem_pestat] mean and std.dev: (559.87, 442.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2412)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 505)
[M::mem_pestat] mean and std.dev: (199.64, 91.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 630)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (344, 591, 1890)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4982)
[M::mem_pestat] mean and std.dev: (958.03, 867.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6528)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 330, 871)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2245)
[M::mem_pestat] mean and std.dev: (460.60, 422.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2932)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724334 sequences (100000055 bp) in 2.958 CPU sec, 3.034 real sec...
[M::process] read 724416 sequences (100000232 bp) in 2.178 CPU sec, 2.178 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (93, 286632, 73, 96)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 345, 831)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1997)
[M::mem_pestat] mean and std.dev: (504.87, 441.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2580)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 508)
[M::mem_pestat] mean and std.dev: (199.88, 91.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 634)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 454, 1156)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3186)
[M::mem_pestat] mean and std.dev: (680.40, 645.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4201)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 383, 974)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2524)
[M::mem_pestat] mean and std.dev: (582.24, 559.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3299)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 725424 reads in 212.983 CPU sec, 6.755 real sec
sorting block 53, #reads = 1076741 mem = 536878897 peak = 996175872
[M::mem_process_seqs] Processed 725108 reads in 151.183 CPU sec, 4.811 real sec
sorting block 54, #reads = 1077870 mem = 536878525 peak = 996175872
[M::process] read 723558 sequences (100000227 bp) in 2.805 CPU sec, 2.883 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (98, 286892, 60, 107)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 337, 1043)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2713)
[M::mem_pestat] mean and std.dev: (542.87, 510.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3548)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 509)
[M::mem_pestat] mean and std.dev: (200.72, 91.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 635)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 592, 1137)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3099)
[M::mem_pestat] mean and std.dev: (636.67, 521.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4080)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 406, 797)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2035)
[M::mem_pestat] mean and std.dev: (493.26, 435.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2654)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724004 sequences (100000103 bp) in 1.929 CPU sec, 1.926 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (103, 287027, 71, 98)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 471, 1138)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3008)
[M::mem_pestat] mean and std.dev: (666.98, 677.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3943)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 509)
[M::mem_pestat] mean and std.dev: (200.99, 91.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 635)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (277, 676, 1283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3295)
[M::mem_pestat] mean and std.dev: (764.38, 676.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4301)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 578, 1218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3186)
[M::mem_pestat] mean and std.dev: (799.21, 751.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4170)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724334 reads in 213.446 CPU sec, 6.772 real sec
[M::mem_process_seqs] Processed 724416 reads in 152.340 CPU sec, 4.865 real sec
sorting block 55, #reads = 1077302 mem = 536879061 peak = 996175872
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (121, 286792, 61, 101)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 316, 762)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1944)
[M::mem_pestat] mean and std.dev: (445.27, 366.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2535)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 184, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 513)
[M::mem_pestat] mean and std.dev: (202.56, 92.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 640)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 624, 1428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3756)
[M::mem_pestat] mean and std.dev: (735.85, 713.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4920)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (289, 632, 1379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3559)
[M::mem_pestat] mean and std.dev: (839.51, 795.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4649)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723458 sequences (100000091 bp) in 2.937 CPU sec, 2.990 real sec...
[M::process] read 723112 sequences (100000067 bp) in 2.440 CPU sec, 2.445 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (112, 286477, 74, 110)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 683, 1319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3461)
[M::mem_pestat] mean and std.dev: (743.11, 644.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4532)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 518)
[M::mem_pestat] mean and std.dev: (202.80, 93.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 647)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 692, 1525)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4255)
[M::mem_pestat] mean and std.dev: (899.03, 989.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5620)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 519, 1168)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3034)
[M::mem_pestat] mean and std.dev: (669.66, 573.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3967)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723558 reads in 214.058 CPU sec, 6.778 real sec
[M::mem_process_seqs] Processed 724004 reads in 152.987 CPU sec, 4.863 real sec
sorting block 56, #reads = 1076594 mem = 536885251 peak = 996175872
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (128, 286548, 64, 92)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 378, 945)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2423)
[M::mem_pestat] mean and std.dev: (598.83, 584.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3162)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 515)
[M::mem_pestat] mean and std.dev: (202.66, 93.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 643)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 497, 1422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3904)
[M::mem_pestat] mean and std.dev: (714.30, 730.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5145)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 452, 1221)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3251)
[M::mem_pestat] mean and std.dev: (687.82, 658.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4266)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727996 sequences (100000211 bp) in 2.942 CPU sec, 3.040 real sec...
[M::process] read 732854 sequences (100000185 bp) in 2.259 CPU sec, 2.257 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (108, 286227, 69, 137)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (246, 396, 1170)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3018)
[M::mem_pestat] mean and std.dev: (644.08, 613.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3942)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 516)
[M::mem_pestat] mean and std.dev: (203.25, 93.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 644)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (300, 597, 1051)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2553)
[M::mem_pestat] mean and std.dev: (619.95, 427.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3304)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (279, 615, 1193)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3021)
[M::mem_pestat] mean and std.dev: (643.55, 535.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3935)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723458 reads in 215.722 CPU sec, 6.841 real sec
sorting block 57, #reads = 1078120 mem = 536883779 peak = 996175872
[M::mem_process_seqs] Processed 723112 reads in 154.197 CPU sec, 4.904 real sec
sorting block 58, #reads = 1076796 mem = 536881722 peak = 998187008
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (86, 287037, 71, 84)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 504, 1174)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3132)
[M::mem_pestat] mean and std.dev: (649.43, 618.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4111)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 178, 249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 491)
[M::mem_pestat] mean and std.dev: (195.29, 88.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 612)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (298, 515, 2390)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6574)
[M::mem_pestat] mean and std.dev: (1367.07, 1673.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8666)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 475, 1431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3791)
[M::mem_pestat] mean and std.dev: (736.90, 712.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4971)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 731698 sequences (100000017 bp) in 3.191 CPU sec, 3.273 real sec...
[M::process] read 730962 sequences (100000117 bp) in 2.460 CPU sec, 2.459 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (96, 289758, 58, 94)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 434, 1252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3322)
[M::mem_pestat] mean and std.dev: (702.60, 756.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4357)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (126, 172, 239)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 465)
[M::mem_pestat] mean and std.dev: (188.33, 83.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 578)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (301, 606, 1100)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2698)
[M::mem_pestat] mean and std.dev: (590.39, 481.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3497)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 501, 1273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3319)
[M::mem_pestat] mean and std.dev: (779.54, 762.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4342)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 727996 reads in 227.209 CPU sec, 7.202 real sec
[M::mem_process_seqs] Processed 732854 reads in 160.584 CPU sec, 5.123 real sec
sorting block 59, #reads = 1075122 mem = 536881485 peak = 998187008
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (88, 289505, 44, 107)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 505, 973)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2497)
[M::mem_pestat] mean and std.dev: (557.43, 487.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3259)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (126, 173, 241)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 471)
[M::mem_pestat] mean and std.dev: (189.53, 84.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 586)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (281, 464, 1268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3242)
[M::mem_pestat] mean and std.dev: (670.60, 687.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4229)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 568, 1233)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3241)
[M::mem_pestat] mean and std.dev: (684.68, 595.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4245)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 730542 sequences (100000077 bp) in 2.932 CPU sec, 3.022 real sec...
[M::process] read 730962 sequences (100000191 bp) in 2.178 CPU sec, 2.179 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (97, 289661, 55, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 376, 1469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3973)
[M::mem_pestat] mean and std.dev: (730.16, 948.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5225)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 175, 243)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 475)
[M::mem_pestat] mean and std.dev: (191.23, 85.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 591)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (312, 672, 2181)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5919)
[M::mem_pestat] mean and std.dev: (1097.13, 1079.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7788)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 425, 1070)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2760)
[M::mem_pestat] mean and std.dev: (705.33, 659.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3605)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 731698 reads in 221.972 CPU sec, 7.049 real sec
sorting block 60, #reads = 1080140 mem = 536881675 peak = 998187008
[M::mem_process_seqs] Processed 730962 reads in 155.612 CPU sec, 4.965 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (87, 289470, 73, 96)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (246, 449, 1182)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3054)
[M::mem_pestat] mean and std.dev: (674.41, 613.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3990)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 175, 245)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 481)
[M::mem_pestat] mean and std.dev: (192.07, 86.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 599)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (132, 404, 1116)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3084)
[M::mem_pestat] mean and std.dev: (582.49, 633.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4068)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 380, 809)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2039)
[M::mem_pestat] mean and std.dev: (523.30, 446.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2654)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 729244 sequences (100000267 bp) in 3.176 CPU sec, 3.244 real sec...
[M::process] read 728732 sequences (100000182 bp) in 2.207 CPU sec, 2.206 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 289782, 58, 95)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 484, 996)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2602)
[M::mem_pestat] mean and std.dev: (611.81, 511.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3405)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (126, 174, 242)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 474)
[M::mem_pestat] mean and std.dev: (190.31, 84.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 590)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 684, 1286)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3394)
[M::mem_pestat] mean and std.dev: (800.73, 724.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4448)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 562, 959)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2403)
[M::mem_pestat] mean and std.dev: (605.58, 489.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3125)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 730542 reads in 212.840 CPU sec, 6.740 real sec
sorting block 61, #reads = 1082462 mem = 536881530 peak = 998187008
[M::mem_process_seqs] Processed 730962 reads in 149.088 CPU sec, 4.738 real sec
sorting block 62, #reads = 1081362 mem = 536878034 peak = 1020592128
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 289114, 69, 90)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 294, 683)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1673)
[M::mem_pestat] mean and std.dev: (448.45, 377.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2168)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 177, 247)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 485)
[M::mem_pestat] mean and std.dev: (193.88, 87.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 604)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 700, 1225)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3201)
[M::mem_pestat] mean and std.dev: (803.33, 672.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4189)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 486, 930)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2396)
[M::mem_pestat] mean and std.dev: (558.62, 470.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3129)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728010 sequences (100000033 bp) in 3.119 CPU sec, 3.202 real sec...
[M::process] read 727994 sequences (100000174 bp) in 2.179 CPU sec, 2.179 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (79, 288909, 65, 97)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 480, 948)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2302)
[M::mem_pestat] mean and std.dev: (579.15, 403.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2979)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 177, 248)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 488)
[M::mem_pestat] mean and std.dev: (194.96, 88.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 608)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 454, 1108)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2878)
[M::mem_pestat] mean and std.dev: (642.44, 540.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3763)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (271, 615, 1391)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3631)
[M::mem_pestat] mean and std.dev: (795.59, 718.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4751)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 729244 reads in 213.212 CPU sec, 6.757 real sec
[M::mem_process_seqs] Processed 728732 reads in 150.296 CPU sec, 4.780 real sec
sorting block 63, #reads = 1082295 mem = 536880770 peak = 1020592128
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 288575, 67, 84)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 304, 819)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2095)
[M::mem_pestat] mean and std.dev: (512.18, 503.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2733)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 178, 250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 492)
[M::mem_pestat] mean and std.dev: (195.91, 89.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 613)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 602, 1654)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4670)
[M::mem_pestat] mean and std.dev: (783.59, 794.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6178)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 333, 1224)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3230)
[M::mem_pestat] mean and std.dev: (608.35, 678.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4233)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 729270 sequences (100000010 bp) in 3.162 CPU sec, 3.253 real sec...
[M::process] read 726926 sequences (100000052 bp) in 2.219 CPU sec, 2.221 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 288774, 66, 84)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 383, 713)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1723)
[M::mem_pestat] mean and std.dev: (448.77, 352.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2228)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 178, 250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 492)
[M::mem_pestat] mean and std.dev: (195.86, 89.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 613)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 1004, 2117)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5887)
[M::mem_pestat] mean and std.dev: (1097.68, 1160.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7772)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 419, 890)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2178)
[M::mem_pestat] mean and std.dev: (537.12, 443.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2822)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 728010 reads in 216.283 CPU sec, 6.863 real sec
sorting block 64, #reads = 1079612 mem = 536878357 peak = 1020592128
[M::mem_process_seqs] Processed 727994 reads in 149.483 CPU sec, 4.759 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (93, 289120, 61, 92)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 391, 1210)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3178)
[M::mem_pestat] mean and std.dev: (782.59, 768.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4162)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 176, 246)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 482)
[M::mem_pestat] mean and std.dev: (193.33, 86.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 600)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (258, 484, 885)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2139)
[M::mem_pestat] mean and std.dev: (551.89, 449.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2766)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 346, 666)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1574)
[M::mem_pestat] mean and std.dev: (398.50, 293.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2028)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727362 sequences (100000005 bp) in 3.284 CPU sec, 3.339 real sec...
[M::process] read 725870 sequences (100000023 bp) in 2.368 CPU sec, 2.379 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (102, 287567, 83, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (253, 612, 1572)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4210)
[M::mem_pestat] mean and std.dev: (838.68, 794.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5529)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 498)
[M::mem_pestat] mean and std.dev: (197.78, 90.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 621)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (297, 1177, 2480)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6846)
[M::mem_pestat] mean and std.dev: (1489.06, 1695.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9029)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 448, 997)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2625)
[M::mem_pestat] mean and std.dev: (568.02, 503.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3439)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 729270 reads in 220.557 CPU sec, 6.982 real sec
sorting block 65, #reads = 1079865 mem = 536886583 peak = 1020592128
[M::mem_process_seqs] Processed 726926 reads in 252.780 CPU sec, 8.038 real sec
sorting block 66, #reads = 1079163 mem = 536875706 peak = 1108516864
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (91, 288609, 63, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 326, 1179)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3155)
[M::mem_pestat] mean and std.dev: (671.69, 749.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4143)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 498)
[M::mem_pestat] mean and std.dev: (197.27, 90.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 621)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (292, 578, 885)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2071)
[M::mem_pestat] mean and std.dev: (582.86, 474.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2664)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 391, 1255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3327)
[M::mem_pestat] mean and std.dev: (640.06, 709.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4363)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724890 sequences (100000044 bp) in 3.211 CPU sec, 3.285 real sec...
[M::process] read 723828 sequences (100000171 bp) in 2.068 CPU sec, 2.063 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (87, 288035, 75, 96)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 388, 622)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1404)
[M::mem_pestat] mean and std.dev: (443.45, 293.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1795)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 180, 255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 505)
[M::mem_pestat] mean and std.dev: (199.54, 92.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 630)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (377, 702, 1818)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4700)
[M::mem_pestat] mean and std.dev: (1038.86, 1057.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6141)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 670, 1289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3409)
[M::mem_pestat] mean and std.dev: (799.99, 722.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4469)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 727362 reads in 213.839 CPU sec, 6.781 real sec
[M::mem_process_seqs] Processed 725870 reads in 243.602 CPU sec, 7.760 real sec
sorting block 67, #reads = 1078574 mem = 536880685 peak = 1108516864
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (85, 287296, 73, 97)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 369, 1242)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3368)
[M::mem_pestat] mean and std.dev: (535.74, 544.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4431)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 182, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 512)
[M::mem_pestat] mean and std.dev: (201.52, 93.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 639)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (319, 554, 1321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3325)
[M::mem_pestat] mean and std.dev: (759.48, 652.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4327)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (393, 778, 1792)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4590)
[M::mem_pestat] mean and std.dev: (1018.04, 864.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5989)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723292 sequences (100000136 bp) in 2.898 CPU sec, 2.961 real sec...
[M::process] read 723082 sequences (100000265 bp) in 2.311 CPU sec, 2.322 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 286331, 84, 101)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 363, 806)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1972)
[M::mem_pestat] mean and std.dev: (456.97, 370.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2555)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 518)
[M::mem_pestat] mean and std.dev: (202.80, 93.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 647)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (108, 522, 1351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3837)
[M::mem_pestat] mean and std.dev: (681.41, 731.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5080)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (264, 477, 869)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2079)
[M::mem_pestat] mean and std.dev: (525.48, 383.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2684)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724890 reads in 219.597 CPU sec, 6.975 real sec
sorting block 68, #reads = 1077972 mem = 536879713 peak = 1108516864
[M::mem_process_seqs] Processed 723828 reads in 161.545 CPU sec, 5.150 real sec
sorting block 69, #reads = 1075439 mem = 536876749 peak = 1108516864
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (98, 285469, 80, 117)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 321, 672)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1610)
[M::mem_pestat] mean and std.dev: (406.69, 301.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2079)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 522)
[M::mem_pestat] mean and std.dev: (204.54, 95.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 652)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (308, 733, 1287)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3245)
[M::mem_pestat] mean and std.dev: (868.32, 823.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4224)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 390, 933)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2427)
[M::mem_pestat] mean and std.dev: (523.66, 512.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3174)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722706 sequences (100000251 bp) in 3.395 CPU sec, 3.452 real sec...
[M::process] read 722954 sequences (100000008 bp) in 2.440 CPU sec, 2.448 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (103, 286207, 73, 134)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (285, 413, 1161)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2913)
[M::mem_pestat] mean and std.dev: (670.92, 613.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3789)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 184, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 519)
[M::mem_pestat] mean and std.dev: (203.86, 94.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 648)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (99, 497, 1325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3777)
[M::mem_pestat] mean and std.dev: (737.87, 822.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5003)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (275, 639, 1246)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3188)
[M::mem_pestat] mean and std.dev: (783.37, 626.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4159)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723082 reads in 228.177 CPU sec, 7.227 real sec
[M::mem_process_seqs] Processed 723292 reads in 262.517 CPU sec, 8.348 real sec
sorting block 70, #reads = 1072452 mem = 536878552 peak = 1108516864
[M::process] read 726926 sequences (100000080 bp) in 2.968 CPU sec, 3.037 real sec...
[M::process] read 734816 sequences (100000164 bp) in 2.530 CPU sec, 2.535 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (109, 286016, 74, 116)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 337, 916)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2308)
[M::mem_pestat] mean and std.dev: (579.23, 564.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3004)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 184, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 519)
[M::mem_pestat] mean and std.dev: (203.96, 94.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 648)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 640, 1645)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4663)
[M::mem_pestat] mean and std.dev: (851.49, 997.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6172)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 466, 1015)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2553)
[M::mem_pestat] mean and std.dev: (604.76, 454.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3322)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 722954 reads in 127.230 CPU sec, 4.032 real sec
sorting block 71, #reads = 1073160 mem = 536883760 peak = 1108516864
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (95, 285874, 82, 110)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (257, 410, 1411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3719)
[M::mem_pestat] mean and std.dev: (757.80, 833.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4873)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 519)
[M::mem_pestat] mean and std.dev: (204.05, 94.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 648)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 523, 899)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2315)
[M::mem_pestat] mean and std.dev: (581.61, 515.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3023)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 576, 1706)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4612)
[M::mem_pestat] mean and std.dev: (1042.93, 1245.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6065)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (87, 287286, 70, 96)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 420, 919)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2383)
[M::mem_pestat] mean and std.dev: (457.91, 344.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3115)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 501)
[M::mem_pestat] mean and std.dev: (198.00, 91.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 625)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 569, 1432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3914)
[M::mem_pestat] mean and std.dev: (711.77, 733.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5155)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 509, 953)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2347)
[M::mem_pestat] mean and std.dev: (609.75, 445.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3044)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 734562 sequences (100000149 bp) in 2.666 CPU sec, 2.678 real sec...
[M::mem_process_seqs] Processed 722706 reads in 355.675 CPU sec, 11.269 real sec
[M::mem_process_seqs] Processed 726926 reads in 196.985 CPU sec, 6.295 real sec
sorting block 72, #reads = 1072839 mem = 536877100 peak = 1108516864
[M::process] read 732772 sequences (100000198 bp) in 2.940 CPU sec, 3.011 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (111, 289733, 88, 88)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (267, 377, 899)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2163)
[M::mem_pestat] mean and std.dev: (580.18, 453.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2795)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (125, 170, 236)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 458)
[M::mem_pestat] mean and std.dev: (185.88, 81.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 569)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 520, 1098)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2892)
[M::mem_pestat] mean and std.dev: (640.71, 619.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3789)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 323, 1196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3202)
[M::mem_pestat] mean and std.dev: (524.09, 556.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4205)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 731734 sequences (100000219 bp) in 2.370 CPU sec, 2.369 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (85, 289966, 56, 114)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 419, 981)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2503)
[M::mem_pestat] mean and std.dev: (596.06, 534.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3264)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (126, 173, 240)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 468)
[M::mem_pestat] mean and std.dev: (189.24, 84.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 582)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 674, 1897)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5179)
[M::mem_pestat] mean and std.dev: (1094.24, 1391.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6820)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 405, 835)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2119)
[M::mem_pestat] mean and std.dev: (512.06, 400.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2761)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (91, 290813, 65, 90)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 370, 1031)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2693)
[M::mem_pestat] mean and std.dev: (543.21, 495.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3524)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (125, 170, 236)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 458)
[M::mem_pestat] mean and std.dev: (186.36, 81.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 569)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (90, 413, 1242)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3546)
[M::mem_pestat] mean and std.dev: (574.40, 664.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4698)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 528, 1377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3665)
[M::mem_pestat] mean and std.dev: (743.98, 712.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4809)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 734816 reads in 333.439 CPU sec, 10.637 real sec
sorting block 73, #reads = 1073942 mem = 536885603 peak = 1108516864
[M::mem_process_seqs] Processed 732772 reads in 267.514 CPU sec, 8.574 real sec
[M::mem_process_seqs] Processed 734562 reads in 303.827 CPU sec, 9.744 real sec
sorting block 74, #reads = 1075388 mem = 536880520 peak = 1108516864
[M::process] read 730932 sequences (100000024 bp) in 3.569 CPU sec, 3.749 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (83, 289847, 82, 89)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 302, 1525)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4195)
[M::mem_pestat] mean and std.dev: (817.42, 959.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5530)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (126, 174, 243)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 477)
[M::mem_pestat] mean and std.dev: (190.93, 85.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 594)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 658, 1189)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3219)
[M::mem_pestat] mean and std.dev: (686.95, 606.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4234)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 426, 1153)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3141)
[M::mem_pestat] mean and std.dev: (584.85, 597.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4135)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 729660 sequences (100000114 bp) in 2.915 CPU sec, 3.006 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (95, 289379, 64, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (266, 613, 1616)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4316)
[M::mem_pestat] mean and std.dev: (1093.53, 1266.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6161)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 175, 245)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 481)
[M::mem_pestat] mean and std.dev: (192.36, 86.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 599)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (131, 516, 1388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3902)
[M::mem_pestat] mean and std.dev: (718.25, 703.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5159)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 499, 1018)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2554)
[M::mem_pestat] mean and std.dev: (539.38, 460.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3322)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 731734 reads in 240.668 CPU sec, 7.631 real sec
[M::process] read 728868 sequences (100000115 bp) in 2.060 CPU sec, 2.062 real sec...
sorting block 75, #reads = 1076373 mem = 536880582 peak = 1108516864
[M::mem_process_seqs] Processed 730932 reads in 175.797 CPU sec, 5.561 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (91, 288879, 72, 92)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 393, 584)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1326)
[M::mem_pestat] mean and std.dev: (403.18, 250.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1697)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 177, 248)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 488)
[M::mem_pestat] mean and std.dev: (194.69, 88.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 608)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 364, 755)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1945)
[M::mem_pestat] mean and std.dev: (446.63, 407.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2540)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 382, 800)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1948)
[M::mem_pestat] mean and std.dev: (474.04, 357.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2522)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728926 sequences (100000018 bp) in 2.949 CPU sec, 3.046 real sec...
[M::process] read 728520 sequences (100000137 bp) in 2.361 CPU sec, 2.370 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (90, 288603, 57, 88)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 382, 811)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2039)
[M::mem_pestat] mean and std.dev: (561.01, 490.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2653)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 177, 248)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 488)
[M::mem_pestat] mean and std.dev: (194.75, 88.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 608)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 1057, 1607)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4389)
[M::mem_pestat] mean and std.dev: (1043.00, 994.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5780)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 364, 1319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3547)
[M::mem_pestat] mean and std.dev: (702.37, 759.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4661)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 729660 reads in 223.478 CPU sec, 7.085 real sec
sorting block 76, #reads = 1074413 mem = 536879667 peak = 1108516864
[M::mem_process_seqs] Processed 728868 reads in 156.841 CPU sec, 4.996 real sec
sorting block 77, #reads = 1077710 mem = 536879253 peak = 1108516864
[M::process] read 728238 sequences (100000070 bp) in 3.212 CPU sec, 3.289 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (99, 288925, 62, 89)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 457, 1222)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3318)
[M::mem_pestat] mean and std.dev: (582.18, 551.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4366)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 177, 249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 491)
[M::mem_pestat] mean and std.dev: (195.10, 88.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 612)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (350, 679, 1283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3149)
[M::mem_pestat] mean and std.dev: (772.95, 565.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4082)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 525, 1263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3303)
[M::mem_pestat] mean and std.dev: (783.58, 655.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4323)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727498 sequences (100000060 bp) in 2.059 CPU sec, 2.063 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (87, 288195, 70, 107)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 357, 737)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1795)
[M::mem_pestat] mean and std.dev: (479.62, 394.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2324)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 178, 251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 497)
[M::mem_pestat] mean and std.dev: (196.42, 90.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 620)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (261, 658, 1719)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4635)
[M::mem_pestat] mean and std.dev: (1079.54, 1075.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6093)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (260, 548, 992)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2456)
[M::mem_pestat] mean and std.dev: (559.37, 393.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3188)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 728926 reads in 245.673 CPU sec, 7.798 real sec
[M::mem_process_seqs] Processed 728520 reads in 279.443 CPU sec, 8.898 real sec
sorting block 78, #reads = 1072699 mem = 536881164 peak = 1108516864
[M::process] read 727306 sequences (100000017 bp) in 2.618 CPU sec, 2.691 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (105, 288356, 68, 117)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 410, 815)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2043)
[M::mem_pestat] mean and std.dev: (518.98, 391.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2657)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 178, 251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 497)
[M::mem_pestat] mean and std.dev: (196.65, 90.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 620)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 489, 821)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2077)
[M::mem_pestat] mean and std.dev: (497.98, 461.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2705)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 451, 1621)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4497)
[M::mem_pestat] mean and std.dev: (954.37, 1115.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5935)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726964 sequences (100000209 bp) in 2.190 CPU sec, 2.190 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (103, 287759, 81, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 533, 1047)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2707)
[M::mem_pestat] mean and std.dev: (586.43, 480.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3537)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 501)
[M::mem_pestat] mean and std.dev: (198.05, 91.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 625)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 454, 1432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3958)
[M::mem_pestat] mean and std.dev: (623.81, 694.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5221)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 539, 1063)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2683)
[M::mem_pestat] mean and std.dev: (697.34, 601.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3493)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (88, 288229, 73, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (263, 485, 949)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2321)
[M::mem_pestat] mean and std.dev: (578.08, 463.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3007)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 501)
[M::mem_pestat] mean and std.dev: (197.88, 91.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 625)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 472, 1000)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2602)
[M::mem_pestat] mean and std.dev: (505.53, 470.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3403)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (319, 563, 1556)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4030)
[M::mem_pestat] mean and std.dev: (756.03, 688.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5267)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 728238 reads in 312.445 CPU sec, 9.964 real sec
sorting block 79, #reads = 1076965 mem = 536880892 peak = 1108516864
[M::mem_process_seqs] Processed 727498 reads in 251.323 CPU sec, 8.054 real sec
sorting block 80, #reads = 1076180 mem = 536877503 peak = 1108516864
[M::process] read 725598 sequences (100000004 bp) in 2.868 CPU sec, 2.949 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 288155, 55, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 384, 983)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2563)
[M::mem_pestat] mean and std.dev: (589.03, 526.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3353)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 501)
[M::mem_pestat] mean and std.dev: (198.25, 91.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 625)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 529, 1305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3387)
[M::mem_pestat] mean and std.dev: (770.18, 814.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4428)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 381, 913)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2339)
[M::mem_pestat] mean and std.dev: (547.70, 508.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3052)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 726964 reads in 127.670 CPU sec, 4.010 real sec
[M::process] read 724626 sequences (100000261 bp) in 2.388 CPU sec, 2.390 real sec...
[M::mem_process_seqs] Processed 727306 reads in 439.821 CPU sec, 14.018 real sec
sorting block 81, #reads = 1075751 mem = 536880532 peak = 1108516864
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (94, 287172, 68, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 501, 998)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2636)
[M::mem_pestat] mean and std.dev: (647.31, 534.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3455)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 511)
[M::mem_pestat] mean and std.dev: (200.90, 93.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 638)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (509, 892, 1455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3347)
[M::mem_pestat] mean and std.dev: (984.00, 673.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4293)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (271, 518, 1394)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3640)
[M::mem_pestat] mean and std.dev: (846.77, 815.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4763)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724684 sequences (100000239 bp) in 3.129 CPU sec, 3.219 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (113, 286398, 96, 111)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (258, 518, 1483)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3933)
[M::mem_pestat] mean and std.dev: (840.30, 797.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5158)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 515)
[M::mem_pestat] mean and std.dev: (202.35, 94.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 643)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (263, 730, 2212)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6110)
[M::mem_pestat] mean and std.dev: (1152.83, 1171.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8059)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (272, 570, 999)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2453)
[M::mem_pestat] mean and std.dev: (639.80, 453.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3180)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725006 sequences (100000250 bp) in 2.310 CPU sec, 2.307 real sec...
[M::mem_process_seqs] Processed 725598 reads in 247.964 CPU sec, 7.830 real sec
[M::mem_process_seqs] Processed 724626 reads in 155.388 CPU sec, 4.931 real sec
sorting block 82, #reads = 1076974 mem = 536876867 peak = 1108516864
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (108, 286439, 65, 95)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 303, 1017)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2685)
[M::mem_pestat] mean and std.dev: (543.90, 535.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3519)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 182, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 512)
[M::mem_pestat] mean and std.dev: (201.31, 93.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 639)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 564, 1201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3267)
[M::mem_pestat] mean and std.dev: (710.21, 721.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4300)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (325, 542, 1075)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2575)
[M::mem_pestat] mean and std.dev: (699.26, 538.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3325)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725004 sequences (100000211 bp) in 3.361 CPU sec, 3.453 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (116, 286639, 80, 96)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 430, 914)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2264)
[M::mem_pestat] mean and std.dev: (494.74, 400.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2939)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 182, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 508)
[M::mem_pestat] mean and std.dev: (200.36, 92.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 634)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 595, 1890)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5342)
[M::mem_pestat] mean and std.dev: (787.78, 870.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7068)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 363, 870)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2212)
[M::mem_pestat] mean and std.dev: (499.54, 459.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2883)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725556 sequences (100000173 bp) in 2.410 CPU sec, 2.415 real sec...
[M::mem_process_seqs] Processed 724684 reads in 213.003 CPU sec, 6.732 real sec
sorting block 83, #reads = 1075280 mem = 536880560 peak = 1108516864
[M::mem_process_seqs] Processed 725006 reads in 151.762 CPU sec, 4.814 real sec
sorting block 84, #reads = 1074745 mem = 536880662 peak = 1108516864
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (92, 286830, 69, 102)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 382, 1080)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2838)
[M::mem_pestat] mean and std.dev: (583.65, 512.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3717)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 181, 255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 503)
[M::mem_pestat] mean and std.dev: (199.76, 91.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 627)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 471, 1162)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3138)
[M::mem_pestat] mean and std.dev: (677.02, 714.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4126)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 289, 586)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1370)
[M::mem_pestat] mean and std.dev: (365.71, 247.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1762)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 731124 sequences (100000117 bp) in 2.986 CPU sec, 3.052 real sec...
[M::process] read 732464 sequences (100000046 bp) in 2.390 CPU sec, 2.387 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (113, 286513, 84, 96)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 434, 1232)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3304)
[M::mem_pestat] mean and std.dev: (686.35, 694.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4340)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 180, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 502)
[M::mem_pestat] mean and std.dev: (198.79, 91.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 626)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 440, 870)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2278)
[M::mem_pestat] mean and std.dev: (465.92, 402.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2982)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 437, 861)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2069)
[M::mem_pestat] mean and std.dev: (552.79, 418.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2673)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 725004 reads in 220.057 CPU sec, 6.966 real sec
[M::mem_process_seqs] Processed 725556 reads in 162.721 CPU sec, 5.175 real sec
sorting block 85, #reads = 1073032 mem = 536879438 peak = 1108516864
[M::process] read 730958 sequences (100000281 bp) in 3.083 CPU sec, 3.162 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (97, 288755, 78, 91)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 342, 1094)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2934)
[M::mem_pestat] mean and std.dev: (641.78, 680.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3854)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 174, 243)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 475)
[M::mem_pestat] mean and std.dev: (191.06, 85.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 591)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 427, 954)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2544)
[M::mem_pestat] mean and std.dev: (543.50, 521.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3339)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 436, 1070)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2780)
[M::mem_pestat] mean and std.dev: (658.74, 613.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3635)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 729970 sequences (100000142 bp) in 2.420 CPU sec, 2.415 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 289817, 44, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 378, 780)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1986)
[M::mem_pestat] mean and std.dev: (512.11, 462.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2589)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (126, 173, 241)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 471)
[M::mem_pestat] mean and std.dev: (189.30, 84.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 586)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 573, 1636)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4456)
[M::mem_pestat] mean and std.dev: (807.73, 803.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5866)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 403, 891)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2205)
[M::mem_pestat] mean and std.dev: (533.40, 445.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2862)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 731124 reads in 233.002 CPU sec, 7.381 real sec
sorting block 86, #reads = 1065221 mem = 536880944 peak = 1108516864
[M::mem_process_seqs] Processed 732464 reads in 158.258 CPU sec, 5.039 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 289428, 65, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 372, 930)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2394)
[M::mem_pestat] mean and std.dev: (490.04, 407.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3126)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 175, 244)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 478)
[M::mem_pestat] mean and std.dev: (191.84, 86.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 595)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (252, 522, 1561)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4179)
[M::mem_pestat] mean and std.dev: (814.56, 911.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5488)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 408, 959)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2475)
[M::mem_pestat] mean and std.dev: (602.35, 557.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3233)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 729138 sequences (100000088 bp) in 2.961 CPU sec, 3.016 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 289383, 60, 90)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 665, 1665)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4483)
[M::mem_pestat] mean and std.dev: (831.19, 716.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5892)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 176, 247)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 485)
[M::mem_pestat] mean and std.dev: (193.61, 87.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 604)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 546, 1254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3466)
[M::mem_pestat] mean and std.dev: (650.69, 722.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4572)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 380, 1271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3377)
[M::mem_pestat] mean and std.dev: (699.95, 694.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4430)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728850 sequences (100000054 bp) in 2.400 CPU sec, 2.405 real sec...
[M::mem_process_seqs] Processed 730958 reads in 205.602 CPU sec, 6.502 real sec
sorting block 87, #reads = 1078886 mem = 536879870 peak = 1108516864
[M::mem_process_seqs] Processed 729970 reads in 144.579 CPU sec, 4.584 real sec
sorting block 88, #reads = 1079489 mem = 536888066 peak = 1108516864
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 289080, 64, 97)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 463, 733)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1713)
[M::mem_pestat] mean and std.dev: (492.27, 316.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2203)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 177, 248)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 488)
[M::mem_pestat] mean and std.dev: (194.58, 88.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 608)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (246, 651, 2049)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5655)
[M::mem_pestat] mean and std.dev: (1107.22, 1064.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7458)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 386, 1006)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2534)
[M::mem_pestat] mean and std.dev: (605.30, 486.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3298)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728380 sequences (100000168 bp) in 3.038 CPU sec, 3.119 real sec...
[M::process] read 727834 sequences (100000002 bp) in 2.200 CPU sec, 2.204 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (88, 289197, 64, 110)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 372, 1087)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2781)
[M::mem_pestat] mean and std.dev: (567.91, 499.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3628)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 177, 249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 491)
[M::mem_pestat] mean and std.dev: (195.27, 88.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 612)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 390, 1103)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3023)
[M::mem_pestat] mean and std.dev: (594.79, 677.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3983)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 314, 960)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2470)
[M::mem_pestat] mean and std.dev: (543.73, 480.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3225)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 729138 reads in 210.201 CPU sec, 6.657 real sec
[M::mem_process_seqs] Processed 728850 reads in 148.627 CPU sec, 4.731 real sec
sorting block 89, #reads = 1080735 mem = 536882161 peak = 1108516864
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (95, 288807, 67, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 464, 898)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2242)
[M::mem_pestat] mean and std.dev: (579.65, 446.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2914)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 178, 250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 494)
[M::mem_pestat] mean and std.dev: (195.94, 89.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 616)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (261, 591, 1611)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4311)
[M::mem_pestat] mean and std.dev: (938.11, 932.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5661)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (264, 621, 1460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3852)
[M::mem_pestat] mean and std.dev: (794.21, 729.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5048)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727676 sequences (100000287 bp) in 3.204 CPU sec, 3.310 real sec...
[M::process] read 727398 sequences (100000211 bp) in 2.012 CPU sec, 2.014 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (84, 288751, 80, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 466, 1144)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2930)
[M::mem_pestat] mean and std.dev: (709.91, 627.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3823)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 498)
[M::mem_pestat] mean and std.dev: (197.38, 90.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 621)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 376, 752)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1950)
[M::mem_pestat] mean and std.dev: (417.61, 400.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2549)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 484, 1393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3765)
[M::mem_pestat] mean and std.dev: (740.78, 660.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4951)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 728380 reads in 214.014 CPU sec, 6.795 real sec
sorting block 90, #reads = 1080563 mem = 536877440 peak = 1108516864
[M::mem_process_seqs] Processed 727834 reads in 151.788 CPU sec, 4.845 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (87, 288298, 60, 93)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 438, 1015)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2605)
[M::mem_pestat] mean and std.dev: (522.55, 398.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3400)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 498)
[M::mem_pestat] mean and std.dev: (197.33, 90.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 621)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (383, 780, 1355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3299)
[M::mem_pestat] mean and std.dev: (876.00, 747.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4271)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (280, 493, 1357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3511)
[M::mem_pestat] mean and std.dev: (789.01, 800.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4588)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727114 sequences (100000095 bp) in 3.634 CPU sec, 3.760 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 288383, 50, 107)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 356, 907)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2345)
[M::mem_pestat] mean and std.dev: (495.13, 445.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3064)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 501)
[M::mem_pestat] mean and std.dev: (198.09, 91.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 625)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 641, 1709)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4713)
[M::mem_pestat] mean and std.dev: (720.24, 768.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6215)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 425, 827)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2061)
[M::mem_pestat] mean and std.dev: (534.06, 436.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2678)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726566 sequences (100000180 bp) in 2.450 CPU sec, 2.447 real sec...
[M::mem_process_seqs] Processed 727676 reads in 224.068 CPU sec, 7.113 real sec
sorting block 91, #reads = 1079472 mem = 536877593 peak = 1108516864
[M::mem_process_seqs] Processed 727398 reads in 158.145 CPU sec, 5.019 real sec
sorting block 92, #reads = 1078536 mem = 536882629 peak = 1108516864
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (83, 287844, 62, 99)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 437, 902)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2364)
[M::mem_pestat] mean and std.dev: (575.43, 528.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3095)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 180, 253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 501)
[M::mem_pestat] mean and std.dev: (198.27, 91.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 625)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (85, 306, 612)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1666)
[M::mem_pestat] mean and std.dev: (354.00, 385.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2193)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 407, 938)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2358)
[M::mem_pestat] mean and std.dev: (511.74, 481.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3068)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726416 sequences (100000056 bp) in 2.964 CPU sec, 3.049 real sec...
[M::process] read 725470 sequences (100000048 bp) in 2.570 CPU sec, 2.573 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (112, 287945, 52, 96)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 289, 1621)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4521)
[M::mem_pestat] mean and std.dev: (705.70, 929.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5971)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 180, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 502)
[M::mem_pestat] mean and std.dev: (198.77, 91.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 626)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (298, 942, 3243)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9133)
[M::mem_pestat] mean and std.dev: (1690.59, 1956.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12078)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 389, 781)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1939)
[M::mem_pestat] mean and std.dev: (520.38, 448.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2518)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 727114 reads in 226.414 CPU sec, 7.197 real sec
[M::mem_process_seqs] Processed 726566 reads in 160.576 CPU sec, 5.125 real sec
sorting block 93, #reads = 1078055 mem = 536879257 peak = 1108516864
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (99, 287972, 72, 117)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 325, 752)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1882)
[M::mem_pestat] mean and std.dev: (456.35, 390.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2447)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 180, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 502)
[M::mem_pestat] mean and std.dev: (198.70, 91.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 626)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 549, 1136)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2966)
[M::mem_pestat] mean and std.dev: (614.38, 555.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3881)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 381, 1063)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2751)
[M::mem_pestat] mean and std.dev: (649.23, 665.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3595)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725300 sequences (100000046 bp) in 3.484 CPU sec, 3.717 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (101, 286865, 74, 85)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 483, 1294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3410)
[M::mem_pestat] mean and std.dev: (757.61, 643.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4468)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 508)
[M::mem_pestat] mean and std.dev: (200.45, 92.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 634)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (285, 599, 1268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3234)
[M::mem_pestat] mean and std.dev: (855.11, 793.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4217)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 498, 1759)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4837)
[M::mem_pestat] mean and std.dev: (940.73, 1110.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6376)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725268 sequences (100000247 bp) in 2.532 CPU sec, 2.537 real sec...
[M::mem_process_seqs] Processed 726416 reads in 230.786 CPU sec, 7.341 real sec
sorting block 94, #reads = 1076904 mem = 536881920 peak = 1108516864
[M::mem_process_seqs] Processed 725470 reads in 166.567 CPU sec, 5.289 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (117, 286162, 57, 98)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 462, 1141)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3017)
[M::mem_pestat] mean and std.dev: (628.61, 598.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3955)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 182, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 508)
[M::mem_pestat] mean and std.dev: (200.19, 92.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 634)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (420, 728, 1421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3423)
[M::mem_pestat] mean and std.dev: (843.46, 694.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4424)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 443, 1293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3367)
[M::mem_pestat] mean and std.dev: (731.67, 671.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4404)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 95, #reads = 1076069 mem = 536878657 peak = 1108516864
[M::process] read 725690 sequences (100000031 bp) in 3.864 CPU sec, 4.047 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (122, 286828, 61, 108)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 398, 840)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2084)
[M::mem_pestat] mean and std.dev: (471.60, 376.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2706)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 508)
[M::mem_pestat] mean and std.dev: (200.40, 92.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 634)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 535, 1576)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4460)
[M::mem_pestat] mean and std.dev: (805.04, 901.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5902)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (258, 471, 1007)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2505)
[M::mem_pestat] mean and std.dev: (614.58, 500.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3254)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725878 sequences (100000205 bp) in 2.586 CPU sec, 2.592 real sec...
[M::mem_process_seqs] Processed 725300 reads in 234.040 CPU sec, 7.429 real sec
[M::mem_process_seqs] Processed 725268 reads in 164.773 CPU sec, 5.237 real sec
sorting block 96, #reads = 1075149 mem = 536878409 peak = 1108516864
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (101, 286920, 65, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 321, 675)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1681)
[M::mem_pestat] mean and std.dev: (431.77, 341.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2184)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 502)
[M::mem_pestat] mean and std.dev: (198.96, 90.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 626)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 553, 1305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3567)
[M::mem_pestat] mean and std.dev: (719.15, 710.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4698)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (308, 498, 1085)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2639)
[M::mem_pestat] mean and std.dev: (597.81, 462.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3416)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725660 sequences (100000251 bp) in 3.737 CPU sec, 3.847 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (101, 286967, 81, 94)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 508, 1498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4066)
[M::mem_pestat] mean and std.dev: (818.94, 836.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5350)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 502)
[M::mem_pestat] mean and std.dev: (198.94, 91.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 626)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (420, 695, 1664)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4152)
[M::mem_pestat] mean and std.dev: (891.74, 792.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5396)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 402, 862)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2156)
[M::mem_pestat] mean and std.dev: (501.10, 493.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2803)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725880 sequences (100000278 bp) in 2.610 CPU sec, 2.611 real sec...
[M::mem_process_seqs] Processed 725690 reads in 234.111 CPU sec, 7.419 real sec
sorting block 97, #reads = 1074293 mem = 536888228 peak = 1108516864
[M::mem_process_seqs] Processed 725878 reads in 164.481 CPU sec, 5.229 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (119, 286986, 75, 101)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 367, 925)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2371)
[M::mem_pestat] mean and std.dev: (519.99, 468.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3094)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 505)
[M::mem_pestat] mean and std.dev: (199.43, 91.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 630)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 486, 961)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2501)
[M::mem_pestat] mean and std.dev: (507.22, 480.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3271)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 406, 728)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1778)
[M::mem_pestat] mean and std.dev: (466.07, 351.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2303)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726648 sequences (100000051 bp) in 3.898 CPU sec, 4.011 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (95, 287207, 78, 101)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 514, 1136)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3032)
[M::mem_pestat] mean and std.dev: (600.25, 543.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3980)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 502)
[M::mem_pestat] mean and std.dev: (198.99, 91.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 626)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (249, 526, 1349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3549)
[M::mem_pestat] mean and std.dev: (849.61, 877.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4649)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 364, 983)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2561)
[M::mem_pestat] mean and std.dev: (495.17, 419.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3350)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 736844 sequences (100000146 bp) in 2.675 CPU sec, 2.684 real sec...
[M::mem_process_seqs] Processed 725660 reads in 239.277 CPU sec, 7.579 real sec
sorting block 98, #reads = 1073861 mem = 536878608 peak = 1108516864
[M::mem_process_seqs] Processed 725880 reads in 171.779 CPU sec, 5.466 real sec
sorting block 99, #reads = 1072854 mem = 536878405 peak = 1108516864
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (95, 286309, 63, 93)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 485, 1144)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3012)
[M::mem_pestat] mean and std.dev: (638.26, 562.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3946)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 498)
[M::mem_pestat] mean and std.dev: (197.43, 90.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 621)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 513, 1192)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3136)
[M::mem_pestat] mean and std.dev: (644.51, 563.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4108)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 371, 984)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2526)
[M::mem_pestat] mean and std.dev: (579.93, 530.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3297)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 735816 sequences (100000052 bp) in 3.785 CPU sec, 3.928 real sec...
[M::process] read 734214 sequences (100000086 bp) in 2.415 CPU sec, 2.423 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (95, 291011, 68, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 440, 942)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2368)
[M::mem_pestat] mean and std.dev: (587.83, 506.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3081)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (123, 168, 233)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 453)
[M::mem_pestat] mean and std.dev: (183.91, 80.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 563)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 631, 1815)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5039)
[M::mem_pestat] mean and std.dev: (814.16, 896.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6651)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 478, 1070)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2708)
[M::mem_pestat] mean and std.dev: (622.53, 518.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3527)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 726648 reads in 268.550 CPU sec, 8.556 real sec
[M::mem_process_seqs] Processed 736844 reads in 183.038 CPU sec, 5.843 real sec
sorting block 100, #reads = 1062403 mem = 536880544 peak = 1108516864
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (85, 290431, 77, 86)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 417, 713)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1757)
[M::mem_pestat] mean and std.dev: (457.71, 336.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2279)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (124, 169, 234)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 454)
[M::mem_pestat] mean and std.dev: (184.74, 80.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 564)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 535, 1033)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2615)
[M::mem_pestat] mean and std.dev: (629.14, 524.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3406)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 449, 1133)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2977)
[M::mem_pestat] mean and std.dev: (765.81, 807.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3995)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 732338 sequences (100000257 bp) in 3.878 CPU sec, 3.968 real sec...
[M::process] read 731110 sequences (100000183 bp) in 2.620 CPU sec, 2.624 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 290424, 70, 94)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 303, 850)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2192)
[M::mem_pestat] mean and std.dev: (536.89, 468.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2863)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (125, 171, 238)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 464)
[M::mem_pestat] mean and std.dev: (187.53, 83.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 577)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (409, 854, 1787)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4543)
[M::mem_pestat] mean and std.dev: (1154.28, 1089.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5921)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 546, 1187)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3059)
[M::mem_pestat] mean and std.dev: (773.17, 690.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3995)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 735816 reads in 256.001 CPU sec, 8.125 real sec
[M::mem_process_seqs] Processed 734214 reads in 178.233 CPU sec, 5.695 real sec
sorting block 101, #reads = 1076227 mem = 536880626 peak = 1108516864
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (87, 289558, 73, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 380, 845)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2095)
[M::mem_pestat] mean and std.dev: (477.14, 370.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2720)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (126, 173, 242)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 474)
[M::mem_pestat] mean and std.dev: (190.22, 85.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 590)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (259, 613, 2051)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5635)
[M::mem_pestat] mean and std.dev: (1006.77, 1118.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7427)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 341, 1017)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2663)
[M::mem_pestat] mean and std.dev: (605.32, 576.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3486)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 730276 sequences (100000066 bp) in 2.779 CPU sec, 2.868 real sec...
[M::process] read 729224 sequences (100000269 bp) in 2.597 CPU sec, 2.600 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (83, 289424, 62, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 437, 1838)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5044)
[M::mem_pestat] mean and std.dev: (902.72, 1058.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6647)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 175, 245)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 481)
[M::mem_pestat] mean and std.dev: (192.31, 86.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 599)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 487, 944)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2508)
[M::mem_pestat] mean and std.dev: (515.54, 453.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3290)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 431, 1348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3532)
[M::mem_pestat] mean and std.dev: (683.16, 642.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4624)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 732338 reads in 237.052 CPU sec, 7.541 real sec
sorting block 102, #reads = 1073241 mem = 536880151 peak = 1108516864
[M::mem_process_seqs] Processed 731110 reads in 165.601 CPU sec, 5.276 real sec
sorting block 103, #reads = 1074147 mem = 536878762 peak = 1110167552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (88, 289512, 63, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 411, 1124)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2992)
[M::mem_pestat] mean and std.dev: (591.19, 567.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3926)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 176, 246)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 484)
[M::mem_pestat] mean and std.dev: (193.53, 87.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 603)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 404, 783)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2037)
[M::mem_pestat] mean and std.dev: (476.02, 432.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2664)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 283, 762)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1878)
[M::mem_pestat] mean and std.dev: (442.52, 421.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2436)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728802 sequences (100000046 bp) in 3.431 CPU sec, 3.515 real sec...
[M::process] read 728760 sequences (100000044 bp) in 2.370 CPU sec, 2.371 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (79, 288975, 75, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 390, 934)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2376)
[M::mem_pestat] mean and std.dev: (621.75, 549.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3097)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 177, 249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 491)
[M::mem_pestat] mean and std.dev: (195.41, 89.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 612)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 555, 1341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3693)
[M::mem_pestat] mean and std.dev: (748.42, 741.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4869)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 554, 1115)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2911)
[M::mem_pestat] mean and std.dev: (667.48, 588.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3809)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 730276 reads in 225.703 CPU sec, 7.156 real sec
[M::mem_process_seqs] Processed 729224 reads in 160.606 CPU sec, 5.100 real sec
sorting block 104, #reads = 1077395 mem = 536885945 peak = 1110167552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 288270, 58, 103)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 364, 716)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1738)
[M::mem_pestat] mean and std.dev: (445.48, 299.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2249)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 177, 250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 494)
[M::mem_pestat] mean and std.dev: (195.84, 89.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 616)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (291, 661, 1212)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3054)
[M::mem_pestat] mean and std.dev: (672.13, 557.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3975)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 433, 1353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3601)
[M::mem_pestat] mean and std.dev: (716.76, 708.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4725)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728084 sequences (100000105 bp) in 3.502 CPU sec, 3.570 real sec...
[M::process] read 727140 sequences (100000286 bp) in 2.490 CPU sec, 2.497 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 288653, 55, 96)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 336, 811)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2101)
[M::mem_pestat] mean and std.dev: (424.43, 378.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2746)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 178, 251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 497)
[M::mem_pestat] mean and std.dev: (196.48, 90.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 620)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 530, 2008)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5602)
[M::mem_pestat] mean and std.dev: (1015.57, 1188.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7399)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (283, 543, 962)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2320)
[M::mem_pestat] mean and std.dev: (618.53, 486.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2999)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 728760 reads in 226.588 CPU sec, 7.179 real sec
sorting block 105, #reads = 1075306 mem = 536884722 peak = 1110167552
[M::mem_process_seqs] Processed 728802 reads in 259.548 CPU sec, 8.265 real sec
sorting block 106, #reads = 1075697 mem = 536882036 peak = 1110167552
[M::process] read 727294 sequences (100000112 bp) in 2.713 CPU sec, 2.790 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (99, 287818, 76, 101)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 539, 994)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2504)
[M::mem_pestat] mean and std.dev: (652.58, 528.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3259)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 178, 250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 492)
[M::mem_pestat] mean and std.dev: (195.82, 89.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 613)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 472, 1102)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2812)
[M::mem_pestat] mean and std.dev: (638.22, 600.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3667)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 449, 1070)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2804)
[M::mem_pestat] mean and std.dev: (658.12, 601.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3671)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727502 sequences (100000137 bp) in 2.440 CPU sec, 2.442 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (107, 287467, 66, 98)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 366, 852)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2176)
[M::mem_pestat] mean and std.dev: (492.26, 429.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2838)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 495)
[M::mem_pestat] mean and std.dev: (196.76, 89.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 617)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (267, 741, 1282)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3312)
[M::mem_pestat] mean and std.dev: (768.09, 762.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4327)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 540, 1006)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2644)
[M::mem_pestat] mean and std.dev: (564.43, 518.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3463)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (101, 287262, 60, 99)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 443, 1177)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3061)
[M::mem_pestat] mean and std.dev: (643.69, 634.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4003)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 495)
[M::mem_pestat] mean and std.dev: (196.91, 89.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 617)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 443, 1865)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5217)
[M::mem_pestat] mean and std.dev: (897.58, 1146.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6893)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 393, 890)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2290)
[M::mem_pestat] mean and std.dev: (531.46, 465.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2990)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 728084 reads in 321.226 CPU sec, 10.243 real sec
[M::mem_process_seqs] Processed 727294 reads in 256.870 CPU sec, 8.218 real sec
[M::mem_process_seqs] Processed 727140 reads in 291.509 CPU sec, 9.322 real sec
sorting block 107, #reads = 1074985 mem = 536876534 peak = 1110167552
[M::process] read 727378 sequences (100000052 bp) in 3.059 CPU sec, 3.149 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (86, 287958, 64, 105)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 576, 1742)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4774)
[M::mem_pestat] mean and std.dev: (889.33, 836.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6290)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 178, 250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 492)
[M::mem_pestat] mean and std.dev: (196.24, 89.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 613)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (104, 454, 1250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3542)
[M::mem_pestat] mean and std.dev: (634.76, 752.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4688)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 449, 1030)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2688)
[M::mem_pestat] mean and std.dev: (603.32, 539.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3517)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 108, #reads = 1073735 mem = 536879282 peak = 1110167552
[M::process] read 726794 sequences (100000166 bp) in 2.983 CPU sec, 3.078 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (86, 287650, 71, 116)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 460, 895)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2305)
[M::mem_pestat] mean and std.dev: (577.54, 496.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3010)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 495)
[M::mem_pestat] mean and std.dev: (196.68, 89.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 617)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (281, 541, 1321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3401)
[M::mem_pestat] mean and std.dev: (818.21, 731.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4441)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 312, 797)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1979)
[M::mem_pestat] mean and std.dev: (441.47, 395.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2570)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725942 sequences (100000132 bp) in 2.149 CPU sec, 2.157 real sec...
[M::mem_process_seqs] Processed 727502 reads in 230.992 CPU sec, 7.336 real sec
[M::mem_process_seqs] Processed 727378 reads in 165.142 CPU sec, 5.241 real sec
sorting block 109, #reads = 1075433 mem = 536877727 peak = 1110167552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 287317, 69, 104)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 289, 908)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2392)
[M::mem_pestat] mean and std.dev: (486.24, 456.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3134)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 498)
[M::mem_pestat] mean and std.dev: (197.76, 90.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 621)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (331, 639, 1227)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3019)
[M::mem_pestat] mean and std.dev: (791.06, 699.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3915)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 545, 1595)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4325)
[M::mem_pestat] mean and std.dev: (937.26, 980.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5690)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725858 sequences (100000261 bp) in 3.227 CPU sec, 3.381 real sec...
[M::process] read 725790 sequences (100000241 bp) in 2.488 CPU sec, 2.490 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (96, 286871, 44, 100)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 393, 996)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2580)
[M::mem_pestat] mean and std.dev: (574.84, 554.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3372)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 180, 253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 499)
[M::mem_pestat] mean and std.dev: (198.13, 90.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 622)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (297, 684, 1571)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4119)
[M::mem_pestat] mean and std.dev: (955.07, 835.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5393)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 538, 1146)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3006)
[M::mem_pestat] mean and std.dev: (694.32, 628.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3936)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 726794 reads in 224.584 CPU sec, 7.114 real sec
sorting block 110, #reads = 1075037 mem = 536878472 peak = 1110167552
[M::mem_process_seqs] Processed 725942 reads in 257.045 CPU sec, 8.172 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (108, 287410, 72, 129)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 471, 979)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2527)
[M::mem_pestat] mean and std.dev: (610.37, 549.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3301)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 180, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 502)
[M::mem_pestat] mean and std.dev: (198.92, 91.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 626)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (287, 600, 1378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3560)
[M::mem_pestat] mean and std.dev: (640.67, 620.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4651)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 352, 1055)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2745)
[M::mem_pestat] mean and std.dev: (612.72, 602.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3590)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725408 sequences (100000038 bp) in 3.219 CPU sec, 3.391 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (102, 287352, 80, 95)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 421, 767)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1907)
[M::mem_pestat] mean and std.dev: (490.18, 416.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2477)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 502)
[M::mem_pestat] mean and std.dev: (199.03, 91.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 626)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 789, 1659)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4535)
[M::mem_pestat] mean and std.dev: (1096.09, 1165.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5973)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (272, 635, 1765)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4751)
[M::mem_pestat] mean and std.dev: (907.53, 882.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6244)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725928 sequences (100000081 bp) in 2.519 CPU sec, 2.561 real sec...
[M::mem_process_seqs] Processed 725858 reads in 219.459 CPU sec, 6.949 real sec
sorting block 111, #reads = 1076152 mem = 536880600 peak = 1110167552
[M::mem_process_seqs] Processed 725790 reads in 154.435 CPU sec, 4.904 real sec
[M::process] read 23348 sequences (3207767 bp) in 0.739 CPU sec, 0.744 real sec...
sorting block 112, #reads = 1076688 mem = 536876142 peak = 1110167552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (86, 286518, 71, 81)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 404, 1233)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3311)
[M::mem_pestat] mean and std.dev: (705.76, 774.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4350)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 505)
[M::mem_pestat] mean and std.dev: (199.86, 91.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 630)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 501, 1110)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2802)
[M::mem_pestat] mean and std.dev: (612.56, 502.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3648)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 526, 1538)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4184)
[M::mem_pestat] mean and std.dev: (779.37, 758.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5507)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (99, 287389, 82, 94)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (249, 373, 969)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2409)
[M::mem_pestat] mean and std.dev: (589.47, 544.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3129)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 502)
[M::mem_pestat] mean and std.dev: (198.85, 91.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 626)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 436, 1049)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2867)
[M::mem_pestat] mean and std.dev: (546.99, 535.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3776)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 381, 683)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1679)
[M::mem_pestat] mean and std.dev: (476.95, 394.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2177)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (6, 9187, 1, 4)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 180, 251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 495)
[M::mem_pestat] mean and std.dev: (196.97, 89.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 617)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_process_seqs] Processed 725408 reads in 215.832 CPU sec, 6.979 real sec
[M::mem_process_seqs] Processed 725928 reads in 154.247 CPU sec, 4.986 real sec
[M::mem_process_seqs] Processed 23348 reads in 155.336 CPU sec, 5.025 real sec
sorting block 113, #reads = 1075173 mem = 536883120 peak = 1110167552
os version: Linux 6.12.88
cpu vendor: GenuineIntel
signature: 000c06f2
features: bfebfbff 7ffefbff
extended: f3bfb7ef fb417ffe
amd bits: 2c100800 00000121
brand: INTEL(R) XEON(R) PLATINUM 8559C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 122048366
overall: 71293329408 mem 21881.082 user 452.906 sys 727.911 real
sorting block 114, #reads = 617296 mem = 308550243 peak = 1124737024
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1029_BICJ-T1-TDNA-1_A23MHWWLT4_1.L003\tPU:L003\tSM:1029_BICJ-T1-TDNA-1_A23MHWWLT4_1\tLB:1029_BICJ-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1029_BICJ-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1029_BICJ-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 727.972 sec; CPU: 22334.015 sec
uniq header count 1
merging 115 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
signature: 000c06f2
features: bfebfbff 7ffefbff
extended: f3bfb7ef fb417ffe
amd bits: 2c100800 00000121
brand: INTEL(R) XEON(R) PLATINUM 8559C
threads: 31 max 192
algo: util-sort
license: sentieon:util=1
output file size: 6769867516
output reads: 123413315
bam_mem_sort: 115 calls 63.070 user 1.634 sys 64.956 real
bam_write: 115 calls 37.238 user 2.226 sys 41.047 real
execute: 1 calls 44.538 user 1.957 sys 780.408 real
merge_files: 1 calls 44.513 user 1.914 sys 51.847 real
parse_chunk: 1834 calls 98.895 user 24.624 sys 125.362 real
read_chunk: 4980 calls 63.821 user 41.271 sys 694.147 real
sort_block: 1 calls 41.856 user 40.652 sys 666.078 real
write_chunk: 3144 calls 44.056 user 1.587 sys 50.734 real
overall: 3798925312 mem 2015.892 user 89.380 sys 780.429 real
ls: cannot access '*.cram': No such file or directory