.command.log - Workdir - DAQ:SENTIEON_BWAMEM (1136_4Z5-T1-TDNA-1_A23MHWWLT4_1;L001;0001)

File Info

Filename: .command.log
Full Path: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/d3/ff0f1c5e31103f02a883b7de99aefb/.command.log
Size: 443.9 KB
Task: DAQ:SENTIEON_BWAMEM (1136_4Z5-T1-TDNA-1_A23MHWWLT4_1;L001;0001)
Attempt
Content

  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/e8/6c2d7dab305ba0929072a4f84f360b/1136_4Z5-T1-TDNA-1_A23MHWWLT4_1/1136_4Z5-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/d3/ff0f1c5e31103f02a883b7de99aefb/.command.sh
  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta.fai
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/e8/6c2d7dab305ba0929072a4f84f360b/1136_4Z5-T1-TDNA-1_A23MHWWLT4_1/1136_4Z5-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/BWAIndex
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/d3/ff0f1c5e31103f02a883b7de99aefb/.command.run
==> STAGING COMPLETE (7 inputs)

cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1136_4Z5-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 2004.133 CPU sec, 79.624 real sec
[M::process] read 728438 sequences (100000025 bp) in 1.348 CPU sec, 1.349 real sec...
[M::process] read 727760 sequences (100000236 bp) in 1.529 CPU sec, 1.536 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 298680, 29, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (254, 388, 1393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3671)
[M::mem_pestat] mean and std.dev: (606.98, 608.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4810)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 185, 267)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 541)
[M::mem_pestat] mean and std.dev: (206.45, 99.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 678)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 296, 1013)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2697)
[M::mem_pestat] mean and std.dev: (497.85, 536.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3539)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 306, 917)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2291)
[M::mem_pestat] mean and std.dev: (453.16, 390.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2978)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726856 sequences (100000048 bp) in 1.548 CPU sec, 1.548 real sec...
[M::process] read 725752 sequences (100000059 bp) in 1.580 CPU sec, 1.585 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 298880, 42, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 427, 972)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2540)
[M::mem_pestat] mean and std.dev: (591.57, 509.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3324)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 186, 269)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 545)
[M::mem_pestat] mean and std.dev: (207.47, 100.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 683)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (349, 691, 1318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3256)
[M::mem_pestat] mean and std.dev: (829.35, 714.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4225)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 319, 1302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3562)
[M::mem_pestat] mean and std.dev: (700.10, 638.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4692)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 728438 reads in 191.085 CPU sec, 6.022 real sec
[M::mem_process_seqs] Processed 727760 reads in 124.589 CPU sec, 3.968 real sec
sorting block 0, #reads = 1095318 mem = 536879341 peak = 603729920
[M::process] read 725848 sequences (100000217 bp) in 1.654 CPU sec, 1.751 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 298415, 37, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 194, 666)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1708)
[M::mem_pestat] mean and std.dev: (364.55, 342.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2229)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 187, 271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 551)
[M::mem_pestat] mean and std.dev: (209.30, 101.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 691)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 348, 907)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2343)
[M::mem_pestat] mean and std.dev: (581.26, 650.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3183)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 352, 1514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4148)
[M::mem_pestat] mean and std.dev: (655.73, 718.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5465)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725134 sequences (100000123 bp) in 1.230 CPU sec, 1.232 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 298192, 54, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 242, 1141)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3073)
[M::mem_pestat] mean and std.dev: (441.32, 502.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4039)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 189, 275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 561)
[M::mem_pestat] mean and std.dev: (211.62, 103.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 704)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (124, 499, 1146)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3190)
[M::mem_pestat] mean and std.dev: (625.49, 573.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4212)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (266, 614, 1246)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3206)
[M::mem_pestat] mean and std.dev: (698.20, 624.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4186)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 726856 reads in 181.656 CPU sec, 5.834 real sec
[M::mem_process_seqs] Processed 725752 reads in 203.434 CPU sec, 6.572 real sec
sorting block 1, #reads = 1095298 mem = 536883028 peak = 761016320
[M::process] read 724796 sequences (100000050 bp) in 1.783 CPU sec, 1.891 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (85, 297674, 55, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (290, 577, 1338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3434)
[M::mem_pestat] mean and std.dev: (846.41, 738.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4482)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 189, 275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 561)
[M::mem_pestat] mean and std.dev: (211.62, 103.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 704)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 362, 935)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2347)
[M::mem_pestat] mean and std.dev: (455.66, 442.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3053)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (292, 1024, 1961)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5299)
[M::mem_pestat] mean and std.dev: (1133.00, 928.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6968)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724402 sequences (100000164 bp) in 1.320 CPU sec, 1.328 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 297540, 41, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 694, 1675)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4651)
[M::mem_pestat] mean and std.dev: (1011.29, 1016.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6139)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 562)
[M::mem_pestat] mean and std.dev: (212.57, 103.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 705)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 296, 904)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2434)
[M::mem_pestat] mean and std.dev: (528.50, 559.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3199)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (294, 392, 1236)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3120)
[M::mem_pestat] mean and std.dev: (741.94, 740.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4062)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 297680, 58, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 324, 729)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1727)
[M::mem_pestat] mean and std.dev: (408.42, 278.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2226)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 189, 276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 562)
[M::mem_pestat] mean and std.dev: (212.09, 103.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 705)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 902, 1852)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5060)
[M::mem_pestat] mean and std.dev: (1115.05, 984.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6664)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 395, 1057)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2781)
[M::mem_pestat] mean and std.dev: (743.23, 829.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4063)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 725848 reads in 255.852 CPU sec, 8.295 real sec
sorting block 2, #reads = 1095684 mem = 536879930 peak = 761016320
[M::mem_process_seqs] Processed 724796 reads in 193.663 CPU sec, 6.260 real sec
[M::mem_process_seqs] Processed 725134 reads in 214.592 CPU sec, 6.944 real sec
sorting block 3, #reads = 1094952 mem = 536877817 peak = 824418304
[M::process] read 723094 sequences (100000053 bp) in 2.694 CPU sec, 2.896 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 297714, 28, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (270, 504, 829)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1947)
[M::mem_pestat] mean and std.dev: (577.87, 444.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2506)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 191, 278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 568)
[M::mem_pestat] mean and std.dev: (213.74, 104.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 713)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (632, 923, 1946)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4574)
[M::mem_pestat] mean and std.dev: (1129.50, 935.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5888)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 351, 852)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2182)
[M::mem_pestat] mean and std.dev: (500.18, 429.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2847)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723894 sequences (100000125 bp) in 1.999 CPU sec, 2.046 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 297522, 49, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 392, 647)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1551)
[M::mem_pestat] mean and std.dev: (384.88, 260.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2003)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 192, 281)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 575)
[M::mem_pestat] mean and std.dev: (215.49, 105.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 722)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 257, 1378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3808)
[M::mem_pestat] mean and std.dev: (598.59, 717.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5023)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (275, 364, 615)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1295)
[M::mem_pestat] mean and std.dev: (430.14, 266.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1635)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724402 reads in 182.723 CPU sec, 5.817 real sec
[M::mem_process_seqs] Processed 723094 reads in 121.755 CPU sec, 3.843 real sec
[M::process] read 723678 sequences (100000238 bp) in 2.083 CPU sec, 2.145 real sec...
sorting block 4, #reads = 1095178 mem = 536879534 peak = 824418304
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 297738, 40, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (120, 339, 907)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2481)
[M::mem_pestat] mean and std.dev: (513.53, 550.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3268)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 192, 281)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 575)
[M::mem_pestat] mean and std.dev: (215.80, 105.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 722)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 980, 1718)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4744)
[M::mem_pestat] mean and std.dev: (1098.77, 896.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6257)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 658, 1720)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4708)
[M::mem_pestat] mean and std.dev: (1042.00, 1089.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6202)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 5, #reads = 1095398 mem = 536878663 peak = 824418304
[M::process] read 724404 sequences (100000100 bp) in 2.329 CPU sec, 2.488 real sec...
[M::process] read 725402 sequences (100000025 bp) in 1.780 CPU sec, 1.784 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 297355, 54, 91)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 392, 1793)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5001)
[M::mem_pestat] mean and std.dev: (1141.13, 1282.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6605)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 192, 282)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 578)
[M::mem_pestat] mean and std.dev: (216.18, 106.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 726)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (260, 911, 1913)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5219)
[M::mem_pestat] mean and std.dev: (1144.00, 1095.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6872)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 377, 1894)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5232)
[M::mem_pestat] mean and std.dev: (1007.75, 1243.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6901)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723894 reads in 177.581 CPU sec, 5.665 real sec
[M::mem_process_seqs] Processed 723678 reads in 118.224 CPU sec, 3.880 real sec
sorting block 6, #reads = 1095153 mem = 536878014 peak = 824418304
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 297723, 40, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (259, 642, 720)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1642)
[M::mem_pestat] mean and std.dev: (485.87, 304.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2103)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 191, 279)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 571)
[M::mem_pestat] mean and std.dev: (214.24, 105.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 717)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (96, 552, 1414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4050)
[M::mem_pestat] mean and std.dev: (721.37, 749.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5368)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 264, 1160)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3164)
[M::mem_pestat] mean and std.dev: (693.49, 782.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4166)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725080 sequences (100000196 bp) in 2.473 CPU sec, 2.652 real sec...
[M::process] read 724422 sequences (100000111 bp) in 1.890 CPU sec, 1.892 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 297831, 46, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (262, 498, 1313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3415)
[M::mem_pestat] mean and std.dev: (678.14, 542.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4466)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 189, 275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 561)
[M::mem_pestat] mean and std.dev: (211.68, 103.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 704)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (477, 953, 1696)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4134)
[M::mem_pestat] mean and std.dev: (1002.41, 811.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5353)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 338, 1773)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4907)
[M::mem_pestat] mean and std.dev: (675.64, 776.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6474)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724404 reads in 187.754 CPU sec, 6.087 real sec
[M::mem_process_seqs] Processed 725402 reads in 122.545 CPU sec, 3.988 real sec
sorting block 7, #reads = 1095100 mem = 536878485 peak = 824418304
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 297709, 40, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 318, 874)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2264)
[M::mem_pestat] mean and std.dev: (414.69, 342.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2959)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 562)
[M::mem_pestat] mean and std.dev: (212.31, 103.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 705)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (457, 854, 2393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6265)
[M::mem_pestat] mean and std.dev: (1369.88, 1258.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8201)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 684, 2022)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5644)
[M::mem_pestat] mean and std.dev: (1123.40, 1277.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7455)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724272 sequences (100000213 bp) in 2.362 CPU sec, 2.492 real sec...
[M::process] read 723742 sequences (100000193 bp) in 1.930 CPU sec, 1.939 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 297799, 52, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 404, 914)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2290)
[M::mem_pestat] mean and std.dev: (543.55, 424.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2978)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 565)
[M::mem_pestat] mean and std.dev: (213.27, 104.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 709)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 372, 797)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2121)
[M::mem_pestat] mean and std.dev: (445.36, 467.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2783)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 489, 1209)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3173)
[M::mem_pestat] mean and std.dev: (767.56, 746.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4155)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 725080 reads in 192.046 CPU sec, 6.212 real sec
sorting block 8, #reads = 1095626 mem = 536884424 peak = 824418304
[M::mem_process_seqs] Processed 724422 reads in 123.835 CPU sec, 3.948 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 297388, 47, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 324, 979)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2563)
[M::mem_pestat] mean and std.dev: (440.70, 408.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3355)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 191, 278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 568)
[M::mem_pestat] mean and std.dev: (213.57, 104.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 713)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (393, 865, 1327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3195)
[M::mem_pestat] mean and std.dev: (753.58, 522.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4129)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 340, 694)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1646)
[M::mem_pestat] mean and std.dev: (419.48, 309.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2122)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 9, #reads = 1096374 mem = 536879082 peak = 824418304
[M::process] read 723418 sequences (100000009 bp) in 2.344 CPU sec, 2.518 real sec...
[M::process] read 723068 sequences (100000229 bp) in 1.950 CPU sec, 1.960 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 297344, 50, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 525, 1462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3950)
[M::mem_pestat] mean and std.dev: (713.33, 693.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5194)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 191, 278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 566)
[M::mem_pestat] mean and std.dev: (213.65, 103.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 710)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 465, 1534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4316)
[M::mem_pestat] mean and std.dev: (764.69, 913.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5707)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 331, 803)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1949)
[M::mem_pestat] mean and std.dev: (545.55, 517.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2615)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724272 reads in 187.175 CPU sec, 5.980 real sec
[M::mem_process_seqs] Processed 723742 reads in 128.880 CPU sec, 4.126 real sec
sorting block 10, #reads = 1094226 mem = 536884229 peak = 824418304
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 296971, 56, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 324, 762)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1882)
[M::mem_pestat] mean and std.dev: (449.44, 378.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2442)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 191, 278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 566)
[M::mem_pestat] mean and std.dev: (213.82, 103.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 710)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 525, 787)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2067)
[M::mem_pestat] mean and std.dev: (530.02, 446.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2707)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 429, 1154)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2960)
[M::mem_pestat] mean and std.dev: (618.62, 629.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3863)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722196 sequences (100000199 bp) in 2.385 CPU sec, 2.559 real sec...
[M::process] read 721924 sequences (100000099 bp) in 1.980 CPU sec, 1.973 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 297011, 32, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 333, 507)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1041)
[M::mem_pestat] mean and std.dev: (337.79, 179.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1308)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 192, 279)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 569)
[M::mem_pestat] mean and std.dev: (214.53, 104.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 714)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (292, 960, 1946)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5254)
[M::mem_pestat] mean and std.dev: (1054.69, 966.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6908)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 294, 818)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2060)
[M::mem_pestat] mean and std.dev: (493.54, 502.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2681)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723418 reads in 184.866 CPU sec, 5.909 real sec
[M::mem_process_seqs] Processed 723068 reads in 126.159 CPU sec, 4.044 real sec
sorting block 11, #reads = 1092598 mem = 536880712 peak = 824418304
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 296703, 42, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 302, 1632)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4558)
[M::mem_pestat] mean and std.dev: (829.38, 947.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6021)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 193, 278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 564)
[M::mem_pestat] mean and std.dev: (214.37, 103.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 707)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 873, 1464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3880)
[M::mem_pestat] mean and std.dev: (891.27, 666.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5088)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 379, 920)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2348)
[M::mem_pestat] mean and std.dev: (478.17, 344.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3062)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721632 sequences (100000080 bp) in 2.719 CPU sec, 2.892 real sec...
[M::process] read 723938 sequences (100000068 bp) in 1.870 CPU sec, 1.862 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 296396, 44, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 315, 538)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1226)
[M::mem_pestat] mean and std.dev: (309.40, 186.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1570)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 193, 279)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 567)
[M::mem_pestat] mean and std.dev: (214.94, 103.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 711)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (260, 687, 1773)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4799)
[M::mem_pestat] mean and std.dev: (1006.49, 935.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6312)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 501, 1292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3456)
[M::mem_pestat] mean and std.dev: (736.02, 654.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4538)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 722196 reads in 182.779 CPU sec, 5.813 real sec
sorting block 12, #reads = 1095011 mem = 536885379 peak = 824418304
[M::mem_process_seqs] Processed 721924 reads in 121.569 CPU sec, 3.864 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 296491, 63, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 434, 1380)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3764)
[M::mem_pestat] mean and std.dev: (831.07, 787.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4956)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 193, 278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 564)
[M::mem_pestat] mean and std.dev: (214.63, 102.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 707)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (351, 533, 2277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6129)
[M::mem_pestat] mean and std.dev: (1381.76, 1581.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8055)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 320, 628)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1460)
[M::mem_pestat] mean and std.dev: (410.43, 307.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1876)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 13, #reads = 1093278 mem = 536880967 peak = 824418304
[M::process] read 723144 sequences (100000073 bp) in 2.812 CPU sec, 2.965 real sec...
[M::process] read 721896 sequences (100000117 bp) in 1.490 CPU sec, 1.484 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 297124, 26, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 396, 1057)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2775)
[M::mem_pestat] mean and std.dev: (663.04, 647.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3634)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 556)
[M::mem_pestat] mean and std.dev: (211.52, 101.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 697)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 516, 1875)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5353)
[M::mem_pestat] mean and std.dev: (987.28, 1205.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7092)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (265, 316, 1118)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2824)
[M::mem_pestat] mean and std.dev: (582.94, 641.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3677)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 721632 reads in 196.709 CPU sec, 6.387 real sec
[M::mem_process_seqs] Processed 723938 reads in 126.689 CPU sec, 4.038 real sec
sorting block 14, #reads = 1092977 mem = 536881459 peak = 824418304
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 296582, 48, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 320, 927)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2459)
[M::mem_pestat] mean and std.dev: (512.33, 497.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3225)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 191, 275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 557)
[M::mem_pestat] mean and std.dev: (212.43, 101.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 698)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (312, 1014, 1327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3357)
[M::mem_pestat] mean and std.dev: (861.30, 691.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4372)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 292, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1004)
[M::mem_pestat] mean and std.dev: (311.94, 181.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1278)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721634 sequences (100000124 bp) in 2.651 CPU sec, 2.814 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 296172, 48, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 433, 1283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3481)
[M::mem_pestat] mean and std.dev: (697.76, 729.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4580)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 193, 277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 561)
[M::mem_pestat] mean and std.dev: (213.44, 101.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 703)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 530, 1671)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4595)
[M::mem_pestat] mean and std.dev: (811.95, 1072.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6057)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 382, 896)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2226)
[M::mem_pestat] mean and std.dev: (511.20, 419.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2891)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721464 sequences (100000058 bp) in 2.140 CPU sec, 2.131 real sec...
[M::mem_process_seqs] Processed 723144 reads in 185.156 CPU sec, 5.982 real sec
[M::mem_process_seqs] Processed 721896 reads in 120.104 CPU sec, 3.802 real sec
sorting block 15, #reads = 1087629 mem = 536879233 peak = 824418304
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 296233, 43, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 529, 998)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2628)
[M::mem_pestat] mean and std.dev: (509.89, 420.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3443)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 192, 277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 561)
[M::mem_pestat] mean and std.dev: (213.40, 101.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 703)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (468, 641, 1051)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2217)
[M::mem_pestat] mean and std.dev: (698.17, 458.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2800)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 427, 906)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2310)
[M::mem_pestat] mean and std.dev: (558.03, 467.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3012)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721196 sequences (100000227 bp) in 2.733 CPU sec, 2.858 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 296066, 42, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (405, 593, 1265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2985)
[M::mem_pestat] mean and std.dev: (782.22, 610.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3845)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 193, 277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 561)
[M::mem_pestat] mean and std.dev: (214.23, 102.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 703)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (429, 1078, 2840)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7662)
[M::mem_pestat] mean and std.dev: (1807.33, 1984.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10073)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 555, 1029)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2573)
[M::mem_pestat] mean and std.dev: (657.33, 528.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3345)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720794 sequences (100000159 bp) in 1.960 CPU sec, 1.968 real sec...
[M::mem_process_seqs] Processed 721634 reads in 181.316 CPU sec, 5.866 real sec
sorting block 16, #reads = 1092628 mem = 536881509 peak = 824418304
[M::mem_process_seqs] Processed 721464 reads in 122.612 CPU sec, 3.903 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 296474, 38, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 356, 870)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2274)
[M::mem_pestat] mean and std.dev: (495.03, 472.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2976)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 193, 277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 559)
[M::mem_pestat] mean and std.dev: (214.22, 102.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 700)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (328, 512, 1875)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4969)
[M::mem_pestat] mean and std.dev: (965.46, 1007.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6516)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 448, 913)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2365)
[M::mem_pestat] mean and std.dev: (474.83, 434.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3091)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 17, #reads = 1093155 mem = 536877678 peak = 828096512
[M::process] read 720592 sequences (100000010 bp) in 2.778 CPU sec, 2.932 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 296339, 39, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 625, 1226)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3386)
[M::mem_pestat] mean and std.dev: (720.42, 597.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4466)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 194, 279)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 565)
[M::mem_pestat] mean and std.dev: (215.08, 102.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 708)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 464, 1358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3712)
[M::mem_pestat] mean and std.dev: (833.65, 1028.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4947)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 374, 775)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1895)
[M::mem_pestat] mean and std.dev: (429.85, 304.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2455)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720196 sequences (100000039 bp) in 1.980 CPU sec, 1.980 real sec...
[M::mem_process_seqs] Processed 721196 reads in 184.586 CPU sec, 5.871 real sec
[M::mem_process_seqs] Processed 720794 reads in 125.204 CPU sec, 3.981 real sec
sorting block 18, #reads = 1091237 mem = 536879344 peak = 828096512
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 296573, 53, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 546, 1001)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2569)
[M::mem_pestat] mean and std.dev: (629.33, 549.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3353)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 195, 280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 568)
[M::mem_pestat] mean and std.dev: (215.85, 102.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 712)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (103, 613, 1646)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4732)
[M::mem_pestat] mean and std.dev: (799.37, 734.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6275)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 317, 839)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2125)
[M::mem_pestat] mean and std.dev: (482.44, 437.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2768)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719870 sequences (100000137 bp) in 2.933 CPU sec, 3.078 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 296083, 41, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 290, 729)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1861)
[M::mem_pestat] mean and std.dev: (431.44, 452.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2427)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 195, 280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 568)
[M::mem_pestat] mean and std.dev: (216.14, 103.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 712)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (324, 618, 1198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2946)
[M::mem_pestat] mean and std.dev: (664.27, 543.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3820)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 439, 965)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2479)
[M::mem_pestat] mean and std.dev: (521.78, 419.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3236)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719800 sequences (100000253 bp) in 1.860 CPU sec, 1.861 real sec...
[M::mem_process_seqs] Processed 720592 reads in 182.583 CPU sec, 5.813 real sec
[M::mem_process_seqs] Processed 720196 reads in 123.911 CPU sec, 3.995 real sec
sorting block 19, #reads = 1090924 mem = 536879003 peak = 828096512
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 295644, 37, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 365, 1127)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2853)
[M::mem_pestat] mean and std.dev: (625.26, 548.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3716)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 195, 281)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 569)
[M::mem_pestat] mean and std.dev: (216.50, 103.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 713)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (439, 933, 1768)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4426)
[M::mem_pestat] mean and std.dev: (1032.26, 880.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5755)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 684, 1246)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3250)
[M::mem_pestat] mean and std.dev: (690.56, 597.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4252)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719146 sequences (100000200 bp) in 2.726 CPU sec, 2.884 real sec...
[M::process] read 719586 sequences (100000048 bp) in 1.950 CPU sec, 1.949 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 295743, 36, 84)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 393, 703)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1699)
[M::mem_pestat] mean and std.dev: (382.00, 254.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2197)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 195, 281)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 569)
[M::mem_pestat] mean and std.dev: (216.53, 103.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 713)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 374, 902)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2244)
[M::mem_pestat] mean and std.dev: (481.45, 361.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2915)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 338, 526)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1128)
[M::mem_pestat] mean and std.dev: (323.18, 159.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1429)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 719870 reads in 183.749 CPU sec, 5.892 real sec
sorting block 20, #reads = 1091931 mem = 536879683 peak = 828096512
[M::mem_process_seqs] Processed 719800 reads in 126.347 CPU sec, 4.035 real sec
sorting block 21, #reads = 1091083 mem = 536878899 peak = 844529664
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 295480, 42, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 269, 1117)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3011)
[M::mem_pestat] mean and std.dev: (619.20, 675.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3958)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 196, 281)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 569)
[M::mem_pestat] mean and std.dev: (217.04, 103.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 713)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (109, 342, 627)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1663)
[M::mem_pestat] mean and std.dev: (362.32, 341.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2181)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 530, 1031)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2657)
[M::mem_pestat] mean and std.dev: (740.56, 640.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3470)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726800 sequences (100000009 bp) in 2.694 CPU sec, 2.805 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 295562, 28, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 413, 519)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1177)
[M::mem_pestat] mean and std.dev: (334.37, 193.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1506)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 196, 282)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 572)
[M::mem_pestat] mean and std.dev: (216.93, 103.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 717)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (85, 624, 1680)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4870)
[M::mem_pestat] mean and std.dev: (820.81, 869.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6465)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 234, 688)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1758)
[M::mem_pestat] mean and std.dev: (347.46, 282.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2293)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726536 sequences (100000038 bp) in 1.949 CPU sec, 1.953 real sec...
[M::mem_process_seqs] Processed 719146 reads in 183.109 CPU sec, 5.809 real sec
[M::mem_process_seqs] Processed 719586 reads in 122.708 CPU sec, 3.903 real sec
sorting block 22, #reads = 1089785 mem = 536877847 peak = 844529664
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 297913, 29, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (267, 511, 1037)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2577)
[M::mem_pestat] mean and std.dev: (605.83, 439.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3347)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 187, 271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 551)
[M::mem_pestat] mean and std.dev: (208.81, 100.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 691)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 940, 2192)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6194)
[M::mem_pestat] mean and std.dev: (1154.54, 1096.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8195)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 489, 995)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2491)
[M::mem_pestat] mean and std.dev: (600.61, 433.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3239)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726218 sequences (100000158 bp) in 2.807 CPU sec, 2.950 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 298258, 67, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 229, 676)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1712)
[M::mem_pestat] mean and std.dev: (394.56, 354.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2230)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 187, 271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 551)
[M::mem_pestat] mean and std.dev: (209.49, 101.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 691)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 444, 1180)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3138)
[M::mem_pestat] mean and std.dev: (706.95, 716.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4117)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 442, 1092)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2864)
[M::mem_pestat] mean and std.dev: (573.37, 626.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3750)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725832 sequences (100000018 bp) in 1.488 CPU sec, 1.486 real sec...
[M::mem_process_seqs] Processed 726800 reads in 176.239 CPU sec, 5.614 real sec
[M::mem_process_seqs] Processed 726536 reads in 118.151 CPU sec, 3.775 real sec
sorting block 23, #reads = 1092391 mem = 536879673 peak = 844529664
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 298266, 40, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 291, 760)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1982)
[M::mem_pestat] mean and std.dev: (446.07, 418.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2593)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 188, 273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 555)
[M::mem_pestat] mean and std.dev: (209.95, 101.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 696)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (273, 947, 1498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3948)
[M::mem_pestat] mean and std.dev: (818.14, 675.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5173)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 372, 965)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2519)
[M::mem_pestat] mean and std.dev: (554.83, 488.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3296)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725456 sequences (100000206 bp) in 2.466 CPU sec, 2.608 real sec...
[M::process] read 725612 sequences (100000216 bp) in 1.490 CPU sec, 1.489 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 298449, 45, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 362, 1172)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3084)
[M::mem_pestat] mean and std.dev: (631.17, 656.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4040)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 189, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 558)
[M::mem_pestat] mean and std.dev: (211.26, 103.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 700)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (430, 985, 1903)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4849)
[M::mem_pestat] mean and std.dev: (1331.18, 1191.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6322)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (313, 444, 839)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1891)
[M::mem_pestat] mean and std.dev: (569.61, 400.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2417)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 726218 reads in 179.873 CPU sec, 5.769 real sec
sorting block 24, #reads = 1095594 mem = 536880947 peak = 844529664
[M::mem_process_seqs] Processed 725832 reads in 117.806 CPU sec, 3.807 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 298239, 49, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 268, 553)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1361)
[M::mem_pestat] mean and std.dev: (306.82, 237.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1765)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 189, 276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 562)
[M::mem_pestat] mean and std.dev: (212.28, 103.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 705)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (454, 862, 1162)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2578)
[M::mem_pestat] mean and std.dev: (723.98, 429.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3286)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 431, 1113)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2881)
[M::mem_pestat] mean and std.dev: (706.84, 619.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3765)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 25, #reads = 1097517 mem = 536880637 peak = 847785984
[M::process] read 725400 sequences (100000094 bp) in 2.587 CPU sec, 2.729 real sec...
[M::process] read 724280 sequences (100000043 bp) in 1.500 CPU sec, 1.501 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 297769, 60, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 321, 598)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1406)
[M::mem_pestat] mean and std.dev: (389.78, 295.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1810)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 189, 275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 561)
[M::mem_pestat] mean and std.dev: (211.77, 103.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 704)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 529, 1338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3580)
[M::mem_pestat] mean and std.dev: (765.39, 764.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4701)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 333, 1152)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2966)
[M::mem_pestat] mean and std.dev: (619.58, 672.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3873)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 725456 reads in 179.702 CPU sec, 5.772 real sec
[M::mem_process_seqs] Processed 725612 reads in 115.825 CPU sec, 3.689 real sec
sorting block 26, #reads = 1097044 mem = 536878376 peak = 847785984
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 297951, 25, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 516, 1378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3774)
[M::mem_pestat] mean and std.dev: (713.28, 753.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4972)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 189, 277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 567)
[M::mem_pestat] mean and std.dev: (212.99, 105.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 712)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (327, 819, 2120)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5706)
[M::mem_pestat] mean and std.dev: (1337.80, 1432.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7499)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 354, 909)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2387)
[M::mem_pestat] mean and std.dev: (493.37, 442.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3126)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723912 sequences (100000183 bp) in 2.803 CPU sec, 2.939 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 297803, 45, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 410, 1742)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4756)
[M::mem_pestat] mean and std.dev: (832.66, 922.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6263)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 191, 279)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 571)
[M::mem_pestat] mean and std.dev: (214.67, 105.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 717)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 441, 780)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2022)
[M::mem_pestat] mean and std.dev: (478.73, 478.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2643)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 322, 1285)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3527)
[M::mem_pestat] mean and std.dev: (620.87, 702.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4648)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 725400 reads in 167.762 CPU sec, 5.327 real sec
[M::process] read 723784 sequences (100000067 bp) in 1.989 CPU sec, 2.000 real sec...
[M::mem_process_seqs] Processed 724280 reads in 111.325 CPU sec, 3.512 real sec
sorting block 27, #reads = 1097350 mem = 536884523 peak = 847785984
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 297149, 47, 81)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 521, 1727)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4761)
[M::mem_pestat] mean and std.dev: (963.61, 1031.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6278)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 192, 281)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 575)
[M::mem_pestat] mean and std.dev: (215.43, 106.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 722)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 468, 1765)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4903)
[M::mem_pestat] mean and std.dev: (900.70, 976.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6472)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 441, 1404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3734)
[M::mem_pestat] mean and std.dev: (796.31, 769.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4899)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723054 sequences (100000184 bp) in 2.695 CPU sec, 2.834 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (86, 297779, 51, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 460, 1095)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2903)
[M::mem_pestat] mean and std.dev: (526.63, 483.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3807)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 192, 282)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 578)
[M::mem_pestat] mean and std.dev: (216.11, 107.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 726)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (412, 818, 3130)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8566)
[M::mem_pestat] mean and std.dev: (1597.96, 1708.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11284)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (296, 414, 1220)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3068)
[M::mem_pestat] mean and std.dev: (734.86, 630.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3992)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723912 reads in 172.394 CPU sec, 5.484 real sec
[M::process] read 723130 sequences (100000211 bp) in 1.890 CPU sec, 1.886 real sec...
sorting block 28, #reads = 1097132 mem = 536878046 peak = 847785984
[M::mem_process_seqs] Processed 723784 reads in 116.601 CPU sec, 3.738 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 297267, 33, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (454, 685, 1268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2896)
[M::mem_pestat] mean and std.dev: (722.03, 463.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3710)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 192, 282)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 578)
[M::mem_pestat] mean and std.dev: (216.61, 107.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 726)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (43, 324, 1629)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4801)
[M::mem_pestat] mean and std.dev: (615.30, 981.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6387)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 561, 977)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2489)
[M::mem_pestat] mean and std.dev: (622.75, 511.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3245)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 29, #reads = 1095181 mem = 536880638 peak = 847785984
[M::process] read 724648 sequences (100000086 bp) in 2.827 CPU sec, 2.938 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 297321, 41, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 378, 1115)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2939)
[M::mem_pestat] mean and std.dev: (575.66, 606.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3851)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 192, 282)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 578)
[M::mem_pestat] mean and std.dev: (216.48, 107.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 726)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 510, 934)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2368)
[M::mem_pestat] mean and std.dev: (673.88, 559.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3085)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 486, 976)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2424)
[M::mem_pestat] mean and std.dev: (627.84, 562.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3148)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724366 sequences (100000129 bp) in 1.940 CPU sec, 1.939 real sec...
[M::mem_process_seqs] Processed 723054 reads in 177.602 CPU sec, 5.693 real sec
[M::mem_process_seqs] Processed 723130 reads in 117.119 CPU sec, 3.783 real sec
sorting block 30, #reads = 1094073 mem = 536879964 peak = 847785984
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 297799, 44, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 333, 915)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2307)
[M::mem_pestat] mean and std.dev: (511.17, 425.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3003)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 562)
[M::mem_pestat] mean and std.dev: (212.86, 104.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 705)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 833, 3026)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8764)
[M::mem_pestat] mean and std.dev: (1514.67, 1872.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11633)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 563, 1151)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3053)
[M::mem_pestat] mean and std.dev: (763.04, 743.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4004)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723946 sequences (100000022 bp) in 2.655 CPU sec, 2.782 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 297849, 56, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (286, 393, 748)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1672)
[M::mem_pestat] mean and std.dev: (456.64, 307.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2134)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 191, 277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 565)
[M::mem_pestat] mean and std.dev: (213.46, 104.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 709)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (448, 1432, 3610)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9934)
[M::mem_pestat] mean and std.dev: (2259.50, 2244.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13096)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 513, 1201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3115)
[M::mem_pestat] mean and std.dev: (711.31, 573.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4072)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722932 sequences (100000181 bp) in 1.950 CPU sec, 1.946 real sec...
[M::mem_process_seqs] Processed 724648 reads in 177.978 CPU sec, 5.742 real sec
[M::mem_process_seqs] Processed 724366 reads in 116.972 CPU sec, 3.823 real sec
sorting block 31, #reads = 1096512 mem = 536878664 peak = 847785984
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 297547, 36, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 322, 917)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2395)
[M::mem_pestat] mean and std.dev: (468.34, 455.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3134)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 191, 278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 568)
[M::mem_pestat] mean and std.dev: (213.98, 104.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 713)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (255, 460, 1291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3363)
[M::mem_pestat] mean and std.dev: (779.12, 781.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4399)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (260, 457, 837)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1991)
[M::mem_pestat] mean and std.dev: (506.43, 393.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2568)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722890 sequences (100000164 bp) in 2.588 CPU sec, 2.701 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 297627, 40, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 672, 1586)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4312)
[M::mem_pestat] mean and std.dev: (985.87, 902.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5675)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 192, 279)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 569)
[M::mem_pestat] mean and std.dev: (214.64, 104.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 714)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 632, 2347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6681)
[M::mem_pestat] mean and std.dev: (1373.69, 1696.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8848)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 653, 2399)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6771)
[M::mem_pestat] mean and std.dev: (1153.35, 1136.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8957)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723190 sequences (100000137 bp) in 1.990 CPU sec, 1.990 real sec...
[M::mem_process_seqs] Processed 723946 reads in 179.202 CPU sec, 5.809 real sec
[M::mem_process_seqs] Processed 722932 reads in 117.085 CPU sec, 3.722 real sec
sorting block 32, #reads = 1095393 mem = 536878894 peak = 847785984
sorting block 33, #reads = 1094462 mem = 536879445 peak = 860504064
[M::process] read 722448 sequences (100000154 bp) in 2.620 CPU sec, 2.718 real sec...
[M::process] read 722824 sequences (100000064 bp) in 1.540 CPU sec, 1.539 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 297217, 46, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 474, 1091)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2825)
[M::mem_pestat] mean and std.dev: (615.69, 501.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3692)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 192, 277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 563)
[M::mem_pestat] mean and std.dev: (213.79, 103.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 706)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 391, 1047)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2773)
[M::mem_pestat] mean and std.dev: (456.23, 505.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3636)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 413, 1731)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4745)
[M::mem_pestat] mean and std.dev: (738.03, 770.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6252)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723190 reads in 99.397 CPU sec, 3.179 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 297319, 46, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 532, 1363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3631)
[M::mem_pestat] mean and std.dev: (758.94, 576.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4765)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 192, 278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 564)
[M::mem_pestat] mean and std.dev: (214.19, 103.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 707)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 576, 1160)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3058)
[M::mem_pestat] mean and std.dev: (778.80, 698.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4007)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (288, 512, 1327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3405)
[M::mem_pestat] mean and std.dev: (796.06, 824.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4444)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 296819, 53, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 255, 506)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1190)
[M::mem_pestat] mean and std.dev: (254.29, 147.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1532)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 192, 278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 564)
[M::mem_pestat] mean and std.dev: (214.35, 103.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 707)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 553, 1182)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3166)
[M::mem_pestat] mean and std.dev: (543.24, 561.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4158)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 567, 942)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2406)
[M::mem_pestat] mean and std.dev: (563.64, 451.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3138)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722762 sequences (100000198 bp) in 1.862 CPU sec, 1.869 real sec...
[M::mem_process_seqs] Processed 722890 reads in 275.470 CPU sec, 8.798 real sec
[M::mem_process_seqs] Processed 722448 reads in 138.867 CPU sec, 4.507 real sec
sorting block 34, #reads = 1094656 mem = 536885489 peak = 860504064
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 296929, 44, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 327, 936)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2438)
[M::mem_pestat] mean and std.dev: (428.82, 384.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3189)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 191, 276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 560)
[M::mem_pestat] mean and std.dev: (212.68, 102.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 702)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (117, 383, 1100)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3066)
[M::mem_pestat] mean and std.dev: (623.63, 675.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4049)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 489, 1624)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4436)
[M::mem_pestat] mean and std.dev: (865.39, 898.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5842)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722896 sequences (100000264 bp) in 2.535 CPU sec, 2.694 real sec...
sorting block 35, #reads = 1093797 mem = 536880529 peak = 860504064
[M::process] read 725384 sequences (100000161 bp) in 1.654 CPU sec, 1.659 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 296695, 43, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 458, 841)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2131)
[M::mem_pestat] mean and std.dev: (542.58, 477.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2776)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 191, 276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 560)
[M::mem_pestat] mean and std.dev: (212.87, 102.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 702)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 323, 897)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2255)
[M::mem_pestat] mean and std.dev: (481.54, 485.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2934)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 294, 590)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1354)
[M::mem_pestat] mean and std.dev: (401.12, 306.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1736)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 722824 reads in 183.991 CPU sec, 5.901 real sec
[M::mem_process_seqs] Processed 722762 reads in 120.330 CPU sec, 3.832 real sec
sorting block 36, #reads = 1092661 mem = 536877420 peak = 860504064
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 296957, 40, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 314, 1022)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2628)
[M::mem_pestat] mean and std.dev: (512.54, 488.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3431)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 191, 275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 557)
[M::mem_pestat] mean and std.dev: (212.43, 101.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 698)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (365, 614, 1437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3581)
[M::mem_pestat] mean and std.dev: (707.60, 665.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4653)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 324, 790)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1968)
[M::mem_pestat] mean and std.dev: (498.45, 420.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2557)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723650 sequences (100000199 bp) in 2.380 CPU sec, 2.536 real sec...
[M::process] read 722210 sequences (100000057 bp) in 1.520 CPU sec, 1.528 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 297366, 40, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 399, 1593)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4413)
[M::mem_pestat] mean and std.dev: (884.47, 870.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5823)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 189, 272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 550)
[M::mem_pestat] mean and std.dev: (210.13, 101.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 689)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (97, 278, 617)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1657)
[M::mem_pestat] mean and std.dev: (401.45, 376.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2177)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 557, 1549)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4179)
[M::mem_pestat] mean and std.dev: (869.36, 844.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5494)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 722896 reads in 181.373 CPU sec, 5.781 real sec
[M::mem_process_seqs] Processed 725384 reads in 128.091 CPU sec, 4.082 real sec
sorting block 37, #reads = 1092218 mem = 536877925 peak = 860504064
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 296706, 41, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 292, 676)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1676)
[M::mem_pestat] mean and std.dev: (420.18, 368.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2176)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 190, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 554)
[M::mem_pestat] mean and std.dev: (211.75, 101.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 694)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (108, 436, 1341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3807)
[M::mem_pestat] mean and std.dev: (801.25, 900.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5040)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 361, 1235)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3307)
[M::mem_pestat] mean and std.dev: (692.71, 633.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4343)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722500 sequences (100000094 bp) in 2.586 CPU sec, 2.704 real sec...
[M::process] read 722182 sequences (100000195 bp) in 1.540 CPU sec, 1.546 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 296333, 45, 88)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 256, 727)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1823)
[M::mem_pestat] mean and std.dev: (425.26, 433.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2371)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 191, 276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 558)
[M::mem_pestat] mean and std.dev: (213.06, 102.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 699)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 1087, 1664)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4530)
[M::mem_pestat] mean and std.dev: (1038.87, 863.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5963)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 601, 1674)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4510)
[M::mem_pestat] mean and std.dev: (1084.59, 1139.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5928)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723650 reads in 187.873 CPU sec, 6.022 real sec
sorting block 38, #reads = 1087638 mem = 536876829 peak = 860504064
[M::mem_process_seqs] Processed 722210 reads in 121.868 CPU sec, 3.889 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 296720, 38, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 395, 915)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2341)
[M::mem_pestat] mean and std.dev: (486.06, 440.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3054)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 192, 277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 561)
[M::mem_pestat] mean and std.dev: (213.50, 102.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 703)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (342, 705, 1450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3666)
[M::mem_pestat] mean and std.dev: (859.36, 765.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4774)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (262, 603, 850)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2026)
[M::mem_pestat] mean and std.dev: (568.98, 403.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2614)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 39, #reads = 1092489 mem = 536888515 peak = 873435136
[M::process] read 721632 sequences (100000110 bp) in 2.818 CPU sec, 2.963 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 296485, 36, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 310, 922)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2368)
[M::mem_pestat] mean and std.dev: (576.26, 630.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3096)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 192, 277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 561)
[M::mem_pestat] mean and std.dev: (213.57, 102.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 703)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 418, 1180)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3120)
[M::mem_pestat] mean and std.dev: (698.17, 611.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4090)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 565, 1005)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2525)
[M::mem_pestat] mean and std.dev: (594.54, 454.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3285)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720844 sequences (100000189 bp) in 1.960 CPU sec, 1.968 real sec...
[M::mem_process_seqs] Processed 722500 reads in 176.935 CPU sec, 5.616 real sec
[M::mem_process_seqs] Processed 722182 reads in 118.616 CPU sec, 3.788 real sec
sorting block 40, #reads = 1091623 mem = 536879869 peak = 873435136
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 296953, 36, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 364, 1023)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2729)
[M::mem_pestat] mean and std.dev: (681.14, 675.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3582)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 193, 278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 564)
[M::mem_pestat] mean and std.dev: (214.14, 102.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 707)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 467, 1153)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3057)
[M::mem_pestat] mean and std.dev: (628.06, 685.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4009)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (284, 645, 1431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3725)
[M::mem_pestat] mean and std.dev: (782.95, 754.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4872)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720324 sequences (100000201 bp) in 2.870 CPU sec, 3.023 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 296221, 50, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 438, 1227)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3273)
[M::mem_pestat] mean and std.dev: (691.55, 674.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4296)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 194, 279)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 565)
[M::mem_pestat] mean and std.dev: (215.22, 102.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 708)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (370, 749, 1076)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2488)
[M::mem_pestat] mean and std.dev: (743.33, 519.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3194)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 323, 778)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1978)
[M::mem_pestat] mean and std.dev: (475.34, 429.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2578)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720466 sequences (100000075 bp) in 1.970 CPU sec, 1.963 real sec...
[M::mem_process_seqs] Processed 721632 reads in 186.082 CPU sec, 5.969 real sec
[M::mem_process_seqs] Processed 720844 reads in 126.374 CPU sec, 4.037 real sec
sorting block 41, #reads = 1093127 mem = 536879845 peak = 873435136
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 296109, 42, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 302, 980)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2586)
[M::mem_pestat] mean and std.dev: (492.63, 520.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3389)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 195, 280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 568)
[M::mem_pestat] mean and std.dev: (216.00, 103.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 712)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (123, 493, 1013)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2793)
[M::mem_pestat] mean and std.dev: (627.78, 617.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3683)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 428, 718)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1666)
[M::mem_pestat] mean and std.dev: (455.89, 314.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2140)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720452 sequences (100000177 bp) in 2.454 CPU sec, 2.588 real sec...
[M::process] read 720348 sequences (100000247 bp) in 1.930 CPU sec, 1.935 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 295600, 41, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 265, 1183)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3211)
[M::mem_pestat] mean and std.dev: (572.56, 723.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4225)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 195, 280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 568)
[M::mem_pestat] mean and std.dev: (216.01, 103.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 712)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (325, 590, 1114)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2692)
[M::mem_pestat] mean and std.dev: (635.71, 549.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3481)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 408, 823)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1967)
[M::mem_pestat] mean and std.dev: (461.51, 328.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2539)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 720324 reads in 186.614 CPU sec, 5.949 real sec
sorting block 42, #reads = 1092765 mem = 536880021 peak = 873435136
[M::mem_process_seqs] Processed 720466 reads in 125.792 CPU sec, 4.069 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 295884, 49, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 575, 1274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3426)
[M::mem_pestat] mean and std.dev: (766.21, 806.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4502)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 195, 280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 568)
[M::mem_pestat] mean and std.dev: (216.13, 103.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 712)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (100, 466, 1662)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4786)
[M::mem_pestat] mean and std.dev: (920.15, 1102.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6348)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 354, 879)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2247)
[M::mem_pestat] mean and std.dev: (532.18, 429.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2931)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 43, #reads = 1090702 mem = 536877962 peak = 892854272
[M::process] read 720472 sequences (100000014 bp) in 2.716 CPU sec, 2.828 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 296059, 42, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 344, 1767)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4827)
[M::mem_pestat] mean and std.dev: (1022.44, 1077.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6357)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 195, 281)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 571)
[M::mem_pestat] mean and std.dev: (216.45, 103.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 716)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 743, 2039)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5709)
[M::mem_pestat] mean and std.dev: (1195.88, 1418.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7544)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 341, 575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1255)
[M::mem_pestat] mean and std.dev: (328.17, 191.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1595)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724486 sequences (100000232 bp) in 2.000 CPU sec, 2.000 real sec...
[M::mem_process_seqs] Processed 720452 reads in 186.285 CPU sec, 5.978 real sec
[M::mem_process_seqs] Processed 720348 reads in 121.441 CPU sec, 3.931 real sec
sorting block 44, #reads = 1090133 mem = 536878909 peak = 892854272
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 296155, 55, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 357, 1463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4017)
[M::mem_pestat] mean and std.dev: (693.48, 757.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5294)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 195, 282)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 574)
[M::mem_pestat] mean and std.dev: (217.17, 104.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 720)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (342, 665, 1919)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5073)
[M::mem_pestat] mean and std.dev: (894.91, 889.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6650)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (275, 562, 2956)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8318)
[M::mem_pestat] mean and std.dev: (1648.67, 2187.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10999)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727782 sequences (100000160 bp) in 2.768 CPU sec, 2.902 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 297512, 42, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (270, 363, 796)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1848)
[M::mem_pestat] mean and std.dev: (475.04, 318.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2374)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 559)
[M::mem_pestat] mean and std.dev: (212.18, 102.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 701)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 497, 1434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3876)
[M::mem_pestat] mean and std.dev: (831.05, 939.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5097)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 343, 1079)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2779)
[M::mem_pestat] mean and std.dev: (546.72, 548.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3629)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726180 sequences (100000266 bp) in 2.060 CPU sec, 2.055 real sec...
[M::mem_process_seqs] Processed 720472 reads in 187.686 CPU sec, 6.051 real sec
[M::mem_process_seqs] Processed 724486 reads in 124.491 CPU sec, 4.000 real sec
sorting block 45, #reads = 1090212 mem = 536890582 peak = 892854272
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 298817, 52, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 342, 961)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2545)
[M::mem_pestat] mean and std.dev: (620.66, 620.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3337)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 186, 269)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 545)
[M::mem_pestat] mean and std.dev: (207.92, 100.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 683)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 308, 1912)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5326)
[M::mem_pestat] mean and std.dev: (590.11, 722.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7033)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 274, 745)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1875)
[M::mem_pestat] mean and std.dev: (362.33, 342.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2440)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725654 sequences (100000116 bp) in 2.972 CPU sec, 3.098 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 298210, 66, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 331, 1322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3558)
[M::mem_pestat] mean and std.dev: (584.08, 597.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4676)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 188, 273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 555)
[M::mem_pestat] mean and std.dev: (210.32, 102.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 696)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 703, 1174)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3104)
[M::mem_pestat] mean and std.dev: (709.31, 689.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4069)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 361, 479)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 933)
[M::mem_pestat] mean and std.dev: (321.63, 145.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1160)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724616 sequences (100000176 bp) in 1.997 CPU sec, 2.005 real sec...
[M::mem_process_seqs] Processed 727782 reads in 193.657 CPU sec, 6.217 real sec
sorting block 46, #reads = 1093327 mem = 536877309 peak = 892854272
[M::mem_process_seqs] Processed 726180 reads in 127.593 CPU sec, 4.091 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 297162, 41, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 507, 1436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3894)
[M::mem_pestat] mean and std.dev: (708.24, 666.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5123)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 189, 275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 561)
[M::mem_pestat] mean and std.dev: (211.34, 102.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 704)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 387, 1951)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5457)
[M::mem_pestat] mean and std.dev: (797.38, 838.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7210)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 388, 1212)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3146)
[M::mem_pestat] mean and std.dev: (612.68, 592.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4113)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 47, #reads = 1096407 mem = 536879333 peak = 916123648
[M::process] read 724218 sequences (100000081 bp) in 2.908 CPU sec, 3.044 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 297769, 47, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (254, 400, 1074)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2714)
[M::mem_pestat] mean and std.dev: (600.95, 586.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3534)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 562)
[M::mem_pestat] mean and std.dev: (212.87, 103.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 705)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (397, 833, 1115)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2551)
[M::mem_pestat] mean and std.dev: (809.00, 481.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3269)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 401, 949)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2401)
[M::mem_pestat] mean and std.dev: (482.98, 509.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3127)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723978 sequences (100000013 bp) in 1.997 CPU sec, 1.997 real sec...
[M::mem_process_seqs] Processed 725654 reads in 190.719 CPU sec, 6.125 real sec
[M::mem_process_seqs] Processed 724616 reads in 127.785 CPU sec, 4.123 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 297827, 49, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 355, 1086)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2930)
[M::mem_pestat] mean and std.dev: (583.34, 587.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3852)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 191, 278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 568)
[M::mem_pestat] mean and std.dev: (214.04, 104.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 713)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (111, 172, 1493)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4257)
[M::mem_pestat] mean and std.dev: (700.00, 946.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5639)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 454, 1294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3432)
[M::mem_pestat] mean and std.dev: (908.60, 1006.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4933)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 48, #reads = 1094042 mem = 536881902 peak = 916123648
[M::process] read 723286 sequences (100000167 bp) in 2.743 CPU sec, 2.900 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 297582, 30, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 249, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1086)
[M::mem_pestat] mean and std.dev: (300.20, 231.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1394)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 191, 279)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 569)
[M::mem_pestat] mean and std.dev: (214.27, 104.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 714)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (67, 247, 637)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1777)
[M::mem_pestat] mean and std.dev: (372.38, 398.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2347)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 427, 783)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1953)
[M::mem_pestat] mean and std.dev: (460.12, 374.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2538)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722862 sequences (100000178 bp) in 1.930 CPU sec, 1.942 real sec...
[M::mem_process_seqs] Processed 724218 reads in 193.405 CPU sec, 6.224 real sec
[M::mem_process_seqs] Processed 723978 reads in 127.673 CPU sec, 4.048 real sec
sorting block 49, #reads = 1094694 mem = 536878502 peak = 916123648
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 297578, 56, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (282, 499, 2137)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5847)
[M::mem_pestat] mean and std.dev: (1151.94, 1179.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7702)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 192, 280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 572)
[M::mem_pestat] mean and std.dev: (215.30, 105.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 718)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 621, 1095)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3009)
[M::mem_pestat] mean and std.dev: (572.84, 546.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3966)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 337, 671)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1625)
[M::mem_pestat] mean and std.dev: (337.86, 236.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2102)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722116 sequences (100000227 bp) in 3.002 CPU sec, 3.270 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 296869, 67, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 482, 649)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1605)
[M::mem_pestat] mean and std.dev: (445.76, 289.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2083)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 193, 283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 581)
[M::mem_pestat] mean and std.dev: (216.89, 106.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 730)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (325, 610, 797)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1741)
[M::mem_pestat] mean and std.dev: (508.93, 324.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2213)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 301, 1213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3287)
[M::mem_pestat] mean and std.dev: (620.73, 666.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4324)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723286 reads in 189.276 CPU sec, 6.179 real sec
[M::process] read 722814 sequences (100000156 bp) in 2.009 CPU sec, 2.024 real sec...
sorting block 50, #reads = 1094233 mem = 536878177 peak = 916123648
[M::mem_process_seqs] Processed 722862 reads in 129.759 CPU sec, 4.458 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 297215, 26, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 408, 844)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2126)
[M::mem_pestat] mean and std.dev: (465.79, 343.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2767)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 285)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 585)
[M::mem_pestat] mean and std.dev: (218.44, 108.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 735)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 407, 926)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2376)
[M::mem_pestat] mean and std.dev: (518.48, 491.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3101)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 341, 873)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2325)
[M::mem_pestat] mean and std.dev: (519.37, 517.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3051)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722516 sequences (100000050 bp) in 2.820 CPU sec, 3.000 real sec...
sorting block 51, #reads = 1095508 mem = 536877053 peak = 916123648
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 297579, 35, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 235, 760)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1884)
[M::mem_pestat] mean and std.dev: (447.33, 439.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2446)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 193, 284)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 584)
[M::mem_pestat] mean and std.dev: (217.83, 108.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 734)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (412, 834, 1323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3145)
[M::mem_pestat] mean and std.dev: (811.53, 640.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4056)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 303, 699)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1635)
[M::mem_pestat] mean and std.dev: (380.70, 321.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2103)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723540 sequences (100000227 bp) in 2.046 CPU sec, 2.116 real sec...
[M::mem_process_seqs] Processed 722116 reads in 196.918 CPU sec, 6.601 real sec
[M::mem_process_seqs] Processed 722814 reads in 129.395 CPU sec, 4.141 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 297305, 38, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 390, 1036)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2700)
[M::mem_pestat] mean and std.dev: (624.19, 511.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3532)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 286)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 588)
[M::mem_pestat] mean and std.dev: (218.74, 108.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 739)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 1114, 2104)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5900)
[M::mem_pestat] mean and std.dev: (1207.52, 1398.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7798)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 324, 873)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2157)
[M::mem_pestat] mean and std.dev: (628.81, 546.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2816)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 52, #reads = 1095047 mem = 536882907 peak = 916123648
[M::process] read 724712 sequences (100000216 bp) in 2.869 CPU sec, 3.173 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 297915, 33, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 225, 643)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1633)
[M::mem_pestat] mean and std.dev: (336.61, 296.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2128)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 191, 279)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 569)
[M::mem_pestat] mean and std.dev: (214.80, 105.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 714)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (286, 732, 1459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3805)
[M::mem_pestat] mean and std.dev: (809.97, 750.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4978)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (298, 421, 932)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2200)
[M::mem_pestat] mean and std.dev: (603.74, 482.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2834)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 722516 reads in 193.161 CPU sec, 6.322 real sec
[M::process] read 723278 sequences (100000168 bp) in 2.368 CPU sec, 2.424 real sec...
[M::mem_process_seqs] Processed 723540 reads in 132.593 CPU sec, 4.474 real sec
sorting block 53, #reads = 1094421 mem = 536880037 peak = 918990848
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 297814, 43, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 307, 549)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1275)
[M::mem_pestat] mean and std.dev: (342.11, 238.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1638)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 189, 275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 559)
[M::mem_pestat] mean and std.dev: (211.93, 103.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 701)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (460, 671, 2612)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6916)
[M::mem_pestat] mean and std.dev: (1412.66, 1555.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9068)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 525, 1645)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4427)
[M::mem_pestat] mean and std.dev: (996.65, 1169.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5818)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722916 sequences (100000125 bp) in 2.750 CPU sec, 3.054 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 297511, 44, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 237, 818)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2034)
[M::mem_pestat] mean and std.dev: (488.98, 468.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2642)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 192, 279)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 569)
[M::mem_pestat] mean and std.dev: (214.69, 105.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 714)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 1233, 2169)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6097)
[M::mem_pestat] mean and std.dev: (1500.38, 1741.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8464)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 348, 1111)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2901)
[M::mem_pestat] mean and std.dev: (536.67, 588.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3796)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724712 reads in 194.475 CPU sec, 6.561 real sec
[M::mem_process_seqs] Processed 723278 reads in 132.111 CPU sec, 4.265 real sec
[M::process] read 722638 sequences (100000008 bp) in 2.312 CPU sec, 2.424 real sec...
sorting block 54, #reads = 1094613 mem = 536879024 peak = 918990848
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 297732, 43, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 382, 909)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2339)
[M::mem_pestat] mean and std.dev: (572.65, 519.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3054)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 192, 280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 572)
[M::mem_pestat] mean and std.dev: (215.29, 105.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 718)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (78, 427, 1225)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3519)
[M::mem_pestat] mean and std.dev: (553.72, 692.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4666)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 470, 750)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1792)
[M::mem_pestat] mean and std.dev: (576.06, 504.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2593)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722062 sequences (100000135 bp) in 2.720 CPU sec, 3.125 real sec...
sorting block 55, #reads = 1093749 mem = 536883437 peak = 954683392
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 297102, 60, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 470, 1177)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3093)
[M::mem_pestat] mean and std.dev: (621.05, 646.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4051)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 192, 278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 564)
[M::mem_pestat] mean and std.dev: (214.67, 104.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 707)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (132, 347, 1903)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5445)
[M::mem_pestat] mean and std.dev: (882.72, 1046.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7216)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 526, 1826)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5072)
[M::mem_pestat] mean and std.dev: (1080.48, 1245.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6695)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 722916 reads in 196.433 CPU sec, 6.374 real sec
[M::process] read 722698 sequences (100000115 bp) in 2.266 CPU sec, 2.318 real sec...
[M::mem_process_seqs] Processed 722638 reads in 139.117 CPU sec, 4.481 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 296793, 32, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 335, 606)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1436)
[M::mem_pestat] mean and std.dev: (390.24, 274.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1851)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 192, 279)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 567)
[M::mem_pestat] mean and std.dev: (214.82, 103.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 711)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 419, 883)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2223)
[M::mem_pestat] mean and std.dev: (555.58, 469.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2893)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 450, 752)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1784)
[M::mem_pestat] mean and std.dev: (453.48, 274.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2300)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 56, #reads = 1093514 mem = 536876855 peak = 954683392
[M::process] read 722180 sequences (100000010 bp) in 2.933 CPU sec, 3.194 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 296712, 41, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (270, 448, 876)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2088)
[M::mem_pestat] mean and std.dev: (537.72, 413.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2694)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 192, 278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 566)
[M::mem_pestat] mean and std.dev: (213.89, 103.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 710)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 575, 1283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3337)
[M::mem_pestat] mean and std.dev: (907.32, 927.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4618)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 374, 1426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3854)
[M::mem_pestat] mean and std.dev: (853.17, 989.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5068)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 722062 reads in 195.259 CPU sec, 6.262 real sec
[M::process] read 722336 sequences (100000195 bp) in 1.978 CPU sec, 1.984 real sec...
[M::mem_process_seqs] Processed 722698 reads in 133.266 CPU sec, 4.470 real sec
sorting block 57, #reads = 1093228 mem = 536882251 peak = 954683392
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 296858, 41, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 523, 1779)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4857)
[M::mem_pestat] mean and std.dev: (1069.45, 1244.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6396)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 192, 277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 561)
[M::mem_pestat] mean and std.dev: (213.74, 102.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 703)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (372, 565, 1189)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2823)
[M::mem_pestat] mean and std.dev: (615.78, 491.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3640)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 359, 1565)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4315)
[M::mem_pestat] mean and std.dev: (936.62, 1107.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5690)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721764 sequences (100000100 bp) in 2.962 CPU sec, 3.290 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 296131, 47, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 425, 1133)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2979)
[M::mem_pestat] mean and std.dev: (708.44, 698.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3902)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 192, 276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 558)
[M::mem_pestat] mean and std.dev: (213.38, 102.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 699)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 598, 1205)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3191)
[M::mem_pestat] mean and std.dev: (677.16, 599.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4184)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 364, 748)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1822)
[M::mem_pestat] mean and std.dev: (490.12, 357.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2359)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724066 sequences (100000106 bp) in 2.010 CPU sec, 2.014 real sec...
[M::mem_process_seqs] Processed 722180 reads in 198.303 CPU sec, 6.594 real sec
sorting block 58, #reads = 1092495 mem = 536876707 peak = 954683392
[M::mem_process_seqs] Processed 722336 reads in 134.806 CPU sec, 4.403 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 296230, 47, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 458, 755)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1885)
[M::mem_pestat] mean and std.dev: (553.87, 423.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2450)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 192, 277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 561)
[M::mem_pestat] mean and std.dev: (213.85, 102.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 703)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 394, 871)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2201)
[M::mem_pestat] mean and std.dev: (535.70, 492.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2866)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 315, 1045)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2695)
[M::mem_pestat] mean and std.dev: (550.22, 550.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3520)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722534 sequences (100000142 bp) in 2.582 CPU sec, 2.790 real sec...
sorting block 59, #reads = 1091268 mem = 536882540 peak = 954683392
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 296718, 68, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 396, 891)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2281)
[M::mem_pestat] mean and std.dev: (500.32, 437.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2976)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 556)
[M::mem_pestat] mean and std.dev: (211.32, 101.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 697)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 641, 1528)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4140)
[M::mem_pestat] mean and std.dev: (914.61, 904.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5446)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 399, 925)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2383)
[M::mem_pestat] mean and std.dev: (496.20, 426.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3112)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722180 sequences (100000185 bp) in 2.091 CPU sec, 2.115 real sec...
[M::mem_process_seqs] Processed 721764 reads in 197.628 CPU sec, 6.453 real sec
[M::mem_process_seqs] Processed 724066 reads in 133.487 CPU sec, 4.380 real sec
sorting block 60, #reads = 1092930 mem = 536878019 peak = 954683392
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 296538, 33, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 278, 730)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1788)
[M::mem_pestat] mean and std.dev: (388.45, 311.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2317)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 191, 276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 560)
[M::mem_pestat] mean and std.dev: (213.03, 102.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 702)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (392, 743, 1629)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4103)
[M::mem_pestat] mean and std.dev: (930.39, 819.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5340)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 507, 1710)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4624)
[M::mem_pestat] mean and std.dev: (984.79, 1181.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6081)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722554 sequences (100000145 bp) in 2.875 CPU sec, 3.269 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 296755, 36, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 304, 1050)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2802)
[M::mem_pestat] mean and std.dev: (630.16, 655.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3678)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 192, 277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 561)
[M::mem_pestat] mean and std.dev: (213.91, 102.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 703)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 428, 1226)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3382)
[M::mem_pestat] mean and std.dev: (671.51, 656.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4460)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 332, 819)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2077)
[M::mem_pestat] mean and std.dev: (534.47, 467.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2706)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722018 sequences (100000195 bp) in 2.081 CPU sec, 2.083 real sec...
[M::mem_process_seqs] Processed 722534 reads in 204.854 CPU sec, 6.692 real sec
[M::mem_process_seqs] Processed 722180 reads in 135.013 CPU sec, 4.381 real sec
sorting block 61, #reads = 1091278 mem = 536880264 peak = 954683392
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 297081, 29, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 338, 1198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3274)
[M::mem_pestat] mean and std.dev: (716.70, 806.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4312)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 192, 277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 563)
[M::mem_pestat] mean and std.dev: (213.76, 103.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 706)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 543, 1019)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2729)
[M::mem_pestat] mean and std.dev: (637.37, 558.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3584)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 344, 850)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2142)
[M::mem_pestat] mean and std.dev: (483.38, 424.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2788)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721866 sequences (100000100 bp) in 2.896 CPU sec, 3.077 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 296318, 35, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 275, 640)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1554)
[M::mem_pestat] mean and std.dev: (347.70, 256.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2011)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 192, 277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 561)
[M::mem_pestat] mean and std.dev: (214.01, 103.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 703)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 357, 1013)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2695)
[M::mem_pestat] mean and std.dev: (476.06, 424.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3536)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (279, 524, 1685)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4497)
[M::mem_pestat] mean and std.dev: (895.20, 788.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5903)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 722554 reads in 190.274 CPU sec, 6.142 real sec
[M::process] read 721822 sequences (100000177 bp) in 2.026 CPU sec, 2.039 real sec...
sorting block 62, #reads = 1093109 mem = 536878612 peak = 954683392
[M::mem_process_seqs] Processed 722018 reads in 127.865 CPU sec, 4.313 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 296376, 44, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 442, 1067)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2819)
[M::mem_pestat] mean and std.dev: (653.34, 681.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3695)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 192, 277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 561)
[M::mem_pestat] mean and std.dev: (214.04, 102.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 703)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 632, 1218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3160)
[M::mem_pestat] mean and std.dev: (833.47, 764.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4131)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 441, 1844)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5042)
[M::mem_pestat] mean and std.dev: (907.35, 920.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6641)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 63, #reads = 1092784 mem = 536881090 peak = 954683392
[M::process] read 721240 sequences (100000249 bp) in 2.673 CPU sec, 2.813 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 296231, 29, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 313, 1104)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2844)
[M::mem_pestat] mean and std.dev: (507.87, 447.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3714)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 721028 sequences (100000142 bp) in 2.034 CPU sec, 2.034 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (135, 193, 277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 561)
[M::mem_pestat] mean and std.dev: (214.01, 102.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 703)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 707, 2402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6864)
[M::mem_pestat] mean and std.dev: (1203.04, 1445.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9095)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 349, 621)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1373)
[M::mem_pestat] mean and std.dev: (418.49, 252.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1749)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 721866 reads in 191.394 CPU sec, 6.355 real sec
[M::mem_process_seqs] Processed 721822 reads in 124.741 CPU sec, 3.961 real sec
sorting block 64, #reads = 1092903 mem = 536879148 peak = 954683392
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 296305, 52, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 360, 817)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2143)
[M::mem_pestat] mean and std.dev: (494.50, 415.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2806)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 193, 278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 564)
[M::mem_pestat] mean and std.dev: (214.78, 103.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 707)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (253, 689, 1148)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2938)
[M::mem_pestat] mean and std.dev: (741.16, 627.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3833)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (294, 540, 959)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2289)
[M::mem_pestat] mean and std.dev: (619.00, 417.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2954)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721496 sequences (100000168 bp) in 2.968 CPU sec, 3.116 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 296390, 41, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 322, 762)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1832)
[M::mem_pestat] mean and std.dev: (503.33, 410.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2367)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 194, 279)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 565)
[M::mem_pestat] mean and std.dev: (215.46, 103.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 708)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (276, 830, 1689)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4515)
[M::mem_pestat] mean and std.dev: (934.93, 734.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5928)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 262, 736)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1828)
[M::mem_pestat] mean and std.dev: (370.85, 336.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2374)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721124 sequences (100000211 bp) in 2.016 CPU sec, 2.025 real sec...
[M::mem_process_seqs] Processed 721240 reads in 195.091 CPU sec, 6.227 real sec
[M::mem_process_seqs] Processed 721028 reads in 129.493 CPU sec, 4.099 real sec
sorting block 65, #reads = 1091985 mem = 536884658 peak = 954683392
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 296501, 52, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 353, 1083)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2845)
[M::mem_pestat] mean and std.dev: (589.81, 667.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3726)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 193, 279)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 567)
[M::mem_pestat] mean and std.dev: (215.23, 103.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 711)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 682, 1359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3597)
[M::mem_pestat] mean and std.dev: (708.82, 581.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4716)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (300, 711, 1264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3192)
[M::mem_pestat] mean and std.dev: (798.76, 657.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4156)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720754 sequences (100000104 bp) in 3.071 CPU sec, 3.229 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 296156, 41, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 387, 948)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2448)
[M::mem_pestat] mean and std.dev: (579.25, 516.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3198)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 193, 279)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 567)
[M::mem_pestat] mean and std.dev: (215.12, 103.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 711)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (319, 700, 1810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4792)
[M::mem_pestat] mean and std.dev: (764.97, 849.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6283)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 346, 721)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1837)
[M::mem_pestat] mean and std.dev: (423.49, 355.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2395)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720306 sequences (100000102 bp) in 2.086 CPU sec, 2.094 real sec...
[M::mem_process_seqs] Processed 721496 reads in 203.297 CPU sec, 6.489 real sec
sorting block 66, #reads = 1091716 mem = 536880350 peak = 954683392
[M::mem_process_seqs] Processed 721124 reads in 136.197 CPU sec, 4.441 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 295990, 39, 88)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 321, 639)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1433)
[M::mem_pestat] mean and std.dev: (352.19, 198.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1830)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 194, 281)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 571)
[M::mem_pestat] mean and std.dev: (216.30, 104.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 716)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 404, 1018)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2770)
[M::mem_pestat] mean and std.dev: (556.95, 500.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3646)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 372, 958)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2404)
[M::mem_pestat] mean and std.dev: (592.04, 537.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3127)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 67, #reads = 1092102 mem = 536877554 peak = 989655040
[M::process] read 725896 sequences (100000193 bp) in 3.033 CPU sec, 3.224 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 295906, 44, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 350, 625)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1421)
[M::mem_pestat] mean and std.dev: (349.50, 222.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1819)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 195, 282)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 574)
[M::mem_pestat] mean and std.dev: (216.89, 104.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 720)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (297, 599, 2214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6048)
[M::mem_pestat] mean and std.dev: (947.66, 884.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7965)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 204, 751)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1909)
[M::mem_pestat] mean and std.dev: (333.16, 347.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2488)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726352 sequences (100000284 bp) in 2.101 CPU sec, 2.110 real sec...
[M::mem_process_seqs] Processed 720754 reads in 204.888 CPU sec, 6.652 real sec
[M::mem_process_seqs] Processed 720306 reads in 136.665 CPU sec, 4.390 real sec
sorting block 68, #reads = 1089914 mem = 536885783 peak = 989655040
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 297767, 43, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (292, 460, 1075)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2641)
[M::mem_pestat] mean and std.dev: (618.41, 569.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3424)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 188, 271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 549)
[M::mem_pestat] mean and std.dev: (209.56, 100.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 688)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 616, 1222)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3324)
[M::mem_pestat] mean and std.dev: (713.51, 662.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4375)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 594, 1222)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3230)
[M::mem_pestat] mean and std.dev: (790.29, 766.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4234)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725766 sequences (100000154 bp) in 2.957 CPU sec, 3.118 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 297804, 51, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 436, 1630)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4510)
[M::mem_pestat] mean and std.dev: (901.23, 1033.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5950)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 187, 271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 549)
[M::mem_pestat] mean and std.dev: (209.02, 101.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 688)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (272, 807, 2037)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5567)
[M::mem_pestat] mean and std.dev: (1174.00, 1093.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7332)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 299, 699)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1635)
[M::mem_pestat] mean and std.dev: (405.00, 296.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2103)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725268 sequences (100000181 bp) in 2.050 CPU sec, 2.061 real sec...
[M::mem_process_seqs] Processed 725896 reads in 202.078 CPU sec, 6.499 real sec
[M::mem_process_seqs] Processed 726352 reads in 133.169 CPU sec, 4.242 real sec
sorting block 69, #reads = 1091303 mem = 536879607 peak = 989655040
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 298028, 46, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 401, 952)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2472)
[M::mem_pestat] mean and std.dev: (564.28, 573.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3232)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 188, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 558)
[M::mem_pestat] mean and std.dev: (210.76, 102.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 700)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (604, 1131, 3973)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10711)
[M::mem_pestat] mean and std.dev: (1999.50, 1812.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14080)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 381, 1127)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2979)
[M::mem_pestat] mean and std.dev: (616.07, 653.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3905)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724402 sequences (100000068 bp) in 2.829 CPU sec, 3.011 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 297911, 37, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 270, 727)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1823)
[M::mem_pestat] mean and std.dev: (396.27, 289.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2371)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 189, 275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 559)
[M::mem_pestat] mean and std.dev: (211.47, 103.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 701)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 326, 950)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2376)
[M::mem_pestat] mean and std.dev: (489.43, 394.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3089)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 437, 1076)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2868)
[M::mem_pestat] mean and std.dev: (671.14, 719.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3764)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724298 sequences (100000086 bp) in 1.929 CPU sec, 1.937 real sec...
[M::mem_process_seqs] Processed 725766 reads in 195.874 CPU sec, 6.260 real sec
sorting block 70, #reads = 1096171 mem = 536879927 peak = 989655040
[M::mem_process_seqs] Processed 725268 reads in 141.472 CPU sec, 4.512 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 297344, 24, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 299, 646)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1582)
[M::mem_pestat] mean and std.dev: (317.24, 215.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2050)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 559)
[M::mem_pestat] mean and std.dev: (212.54, 103.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 701)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 503, 833)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2145)
[M::mem_pestat] mean and std.dev: (542.61, 489.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2801)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 329, 1193)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3201)
[M::mem_pestat] mean and std.dev: (649.92, 650.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4205)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 71, #reads = 1096726 mem = 536884226 peak = 989655040
[M::process] read 723488 sequences (100000141 bp) in 3.061 CPU sec, 3.229 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 297189, 32, 95)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (286, 638, 1496)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3916)
[M::mem_pestat] mean and std.dev: (885.47, 896.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5126)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 191, 277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 565)
[M::mem_pestat] mean and std.dev: (213.20, 104.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 709)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (409, 979, 1672)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4198)
[M::mem_pestat] mean and std.dev: (1162.56, 913.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5461)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 419, 1084)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2740)
[M::mem_pestat] mean and std.dev: (678.65, 641.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3568)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723332 sequences (100000011 bp) in 2.054 CPU sec, 2.061 real sec...
[M::mem_process_seqs] Processed 724402 reads in 195.635 CPU sec, 6.245 real sec
[M::mem_process_seqs] Processed 724298 reads in 141.546 CPU sec, 4.513 real sec
sorting block 72, #reads = 1094266 mem = 536881417 peak = 989655040
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 297439, 53, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 433, 655)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1603)
[M::mem_pestat] mean and std.dev: (363.90, 221.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2077)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 191, 280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 572)
[M::mem_pestat] mean and std.dev: (215.15, 105.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 718)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 852, 2108)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5922)
[M::mem_pestat] mean and std.dev: (1236.44, 1276.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7829)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 418, 843)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2019)
[M::mem_pestat] mean and std.dev: (450.67, 336.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2607)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722312 sequences (100000058 bp) in 3.003 CPU sec, 3.150 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 297606, 37, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (280, 364, 961)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2323)
[M::mem_pestat] mean and std.dev: (452.12, 305.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3004)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 192, 279)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 569)
[M::mem_pestat] mean and std.dev: (214.85, 105.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 714)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (337, 603, 1826)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4804)
[M::mem_pestat] mean and std.dev: (1124.80, 1170.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6293)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (283, 1111, 2096)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5722)
[M::mem_pestat] mean and std.dev: (1015.34, 980.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7535)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723488 reads in 193.549 CPU sec, 6.181 real sec
[M::process] read 721608 sequences (100000175 bp) in 2.120 CPU sec, 2.125 real sec...
sorting block 73, #reads = 1094687 mem = 536881689 peak = 989655040
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 296890, 45, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 219, 627)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1523)
[M::mem_pestat] mean and std.dev: (364.05, 329.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1971)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 193, 284)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 582)
[M::mem_pestat] mean and std.dev: (217.64, 107.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 731)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (39, 440, 1386)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4080)
[M::mem_pestat] mean and std.dev: (772.37, 838.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5427)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (277, 385, 772)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1762)
[M::mem_pestat] mean and std.dev: (479.83, 365.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2257)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721766 sequences (100000162 bp) in 2.244 CPU sec, 2.255 real sec...
[M::mem_process_seqs] Processed 722312 reads in 115.622 CPU sec, 3.947 real sec
[M::mem_process_seqs] Processed 723332 reads in 291.227 CPU sec, 9.568 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 296680, 39, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (269, 410, 1366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3560)
[M::mem_pestat] mean and std.dev: (801.27, 722.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4657)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 285)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 585)
[M::mem_pestat] mean and std.dev: (218.33, 107.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 735)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 465, 1178)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3266)
[M::mem_pestat] mean and std.dev: (702.94, 805.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4310)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (307, 477, 912)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2122)
[M::mem_pestat] mean and std.dev: (542.46, 397.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2727)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 74, #reads = 1095120 mem = 536884060 peak = 989655040
[M::process] read 721358 sequences (100000170 bp) in 2.946 CPU sec, 3.222 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 296893, 48, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 434, 2064)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5892)
[M::mem_pestat] mean and std.dev: (1140.28, 1268.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7806)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 285)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 585)
[M::mem_pestat] mean and std.dev: (218.28, 107.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 735)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 669, 1286)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3560)
[M::mem_pestat] mean and std.dev: (775.91, 625.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4697)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 381, 856)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2108)
[M::mem_pestat] mean and std.dev: (525.85, 449.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2734)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 721608 reads in 217.211 CPU sec, 6.950 real sec
[M::mem_process_seqs] Processed 721766 reads in 134.027 CPU sec, 4.249 real sec
[M::process] read 723514 sequences (100000026 bp) in 2.399 CPU sec, 2.478 real sec...
sorting block 75, #reads = 1094203 mem = 536879637 peak = 989655040
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 296440, 56, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 419, 754)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1772)
[M::mem_pestat] mean and std.dev: (496.93, 381.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2281)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 195, 286)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 588)
[M::mem_pestat] mean and std.dev: (218.92, 108.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 739)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 648, 889)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2235)
[M::mem_pestat] mean and std.dev: (610.59, 494.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2908)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 608, 1174)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3072)
[M::mem_pestat] mean and std.dev: (748.50, 580.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4021)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723702 sequences (100000103 bp) in 2.762 CPU sec, 2.944 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 297556, 38, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (253, 378, 1580)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4234)
[M::mem_pestat] mean and std.dev: (858.63, 898.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5561)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 191, 278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 566)
[M::mem_pestat] mean and std.dev: (214.01, 104.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 710)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (74, 252, 831)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2345)
[M::mem_pestat] mean and std.dev: (417.12, 511.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3102)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 373, 762)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1892)
[M::mem_pestat] mean and std.dev: (462.70, 351.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2457)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722788 sequences (100000299 bp) in 1.858 CPU sec, 1.866 real sec...
[M::mem_process_seqs] Processed 721358 reads in 197.085 CPU sec, 6.295 real sec
sorting block 76, #reads = 1094621 mem = 536883797 peak = 989655040
[M::mem_process_seqs] Processed 723514 reads in 135.157 CPU sec, 4.563 real sec
sorting block 77, #reads = 1094193 mem = 536884116 peak = 989655040
[M::process] read 722018 sequences (100000068 bp) in 2.961 CPU sec, 3.139 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 297071, 48, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 344, 1200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3162)
[M::mem_pestat] mean and std.dev: (737.22, 753.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4143)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 192, 280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 572)
[M::mem_pestat] mean and std.dev: (215.29, 105.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 718)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (255, 660, 1172)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3006)
[M::mem_pestat] mean and std.dev: (748.44, 651.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3923)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 343, 1647)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4511)
[M::mem_pestat] mean and std.dev: (823.03, 911.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5943)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723142 sequences (100000276 bp) in 2.017 CPU sec, 2.027 real sec...
[M::mem_process_seqs] Processed 722788 reads in 115.765 CPU sec, 3.677 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 297299, 52, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 279, 706)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1800)
[M::mem_pestat] mean and std.dev: (385.09, 352.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2347)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 190, 276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 560)
[M::mem_pestat] mean and std.dev: (212.83, 103.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 702)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 499, 964)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2554)
[M::mem_pestat] mean and std.dev: (475.50, 426.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3349)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 584, 1315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3521)
[M::mem_pestat] mean and std.dev: (760.35, 660.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4624)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (83, 296716, 46, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 343, 1002)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2632)
[M::mem_pestat] mean and std.dev: (583.36, 625.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3447)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 192, 279)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 567)
[M::mem_pestat] mean and std.dev: (214.93, 104.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 711)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (127, 591, 1270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3556)
[M::mem_pestat] mean and std.dev: (751.42, 786.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4699)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 362, 953)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2549)
[M::mem_pestat] mean and std.dev: (592.02, 608.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3347)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723702 reads in 305.164 CPU sec, 10.009 real sec
[M::process] read 722242 sequences (100000084 bp) in 2.152 CPU sec, 2.175 real sec...
[M::mem_process_seqs] Processed 722018 reads in 156.626 CPU sec, 5.033 real sec
sorting block 78, #reads = 1094091 mem = 536879550 peak = 989655040
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 297476, 36, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 370, 852)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2174)
[M::mem_pestat] mean and std.dev: (479.67, 411.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2835)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 191, 277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 563)
[M::mem_pestat] mean and std.dev: (213.51, 103.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 706)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 784, 2574)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7316)
[M::mem_pestat] mean and std.dev: (1196.44, 1258.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9687)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 491, 1316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3500)
[M::mem_pestat] mean and std.dev: (785.13, 717.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4592)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 79, #reads = 1094784 mem = 536881582 peak = 989655040
[M::process] read 722310 sequences (100000180 bp) in 2.955 CPU sec, 3.130 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 296323, 50, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 248, 1103)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2971)
[M::mem_pestat] mean and std.dev: (535.91, 600.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3905)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 192, 277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 561)
[M::mem_pestat] mean and std.dev: (213.60, 102.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 703)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 549, 916)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2308)
[M::mem_pestat] mean and std.dev: (545.45, 357.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3004)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 274, 563)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1245)
[M::mem_pestat] mean and std.dev: (392.18, 279.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1586)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722326 sequences (100000081 bp) in 2.069 CPU sec, 2.079 real sec...
[M::mem_process_seqs] Processed 723142 reads in 199.883 CPU sec, 6.403 real sec
[M::mem_process_seqs] Processed 722242 reads in 133.971 CPU sec, 4.348 real sec
sorting block 80, #reads = 1094579 mem = 536884498 peak = 989655040
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 296539, 42, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (279, 578, 1224)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3114)
[M::mem_pestat] mean and std.dev: (724.19, 646.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4059)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 192, 278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 564)
[M::mem_pestat] mean and std.dev: (214.23, 103.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 707)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 606, 1423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3887)
[M::mem_pestat] mean and std.dev: (893.00, 811.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5119)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 338, 1015)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2713)
[M::mem_pestat] mean and std.dev: (651.36, 708.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3562)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722012 sequences (100000091 bp) in 3.086 CPU sec, 3.289 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 296416, 38, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (269, 555, 871)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2075)
[M::mem_pestat] mean and std.dev: (591.78, 408.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2677)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 192, 276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 558)
[M::mem_pestat] mean and std.dev: (213.13, 102.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 699)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 473, 1282)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3484)
[M::mem_pestat] mean and std.dev: (684.14, 766.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4585)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 284, 996)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2618)
[M::mem_pestat] mean and std.dev: (454.96, 541.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3429)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721850 sequences (100000205 bp) in 2.064 CPU sec, 2.072 real sec...
[M::mem_process_seqs] Processed 722310 reads in 203.977 CPU sec, 6.596 real sec
[M::mem_process_seqs] Processed 722326 reads in 134.107 CPU sec, 4.255 real sec
sorting block 81, #reads = 1092777 mem = 536878763 peak = 989655040
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 295881, 57, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 329, 848)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2110)
[M::mem_pestat] mean and std.dev: (496.17, 402.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2741)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 192, 277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 561)
[M::mem_pestat] mean and std.dev: (213.79, 102.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 703)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 508, 1324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3604)
[M::mem_pestat] mean and std.dev: (809.80, 926.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4744)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 377, 883)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2311)
[M::mem_pestat] mean and std.dev: (432.77, 433.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3025)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721594 sequences (100000246 bp) in 2.877 CPU sec, 3.046 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 296627, 43, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 278, 584)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1322)
[M::mem_pestat] mean and std.dev: (371.22, 280.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1691)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 192, 277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 561)
[M::mem_pestat] mean and std.dev: (213.81, 102.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 703)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 852, 2492)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7002)
[M::mem_pestat] mean and std.dev: (1287.10, 1137.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9257)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 308, 1013)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2715)
[M::mem_pestat] mean and std.dev: (556.03, 581.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3566)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721772 sequences (100000142 bp) in 2.041 CPU sec, 2.049 real sec...
[M::mem_process_seqs] Processed 722012 reads in 200.747 CPU sec, 6.507 real sec
sorting block 82, #reads = 1091800 mem = 536876699 peak = 989655040
[M::mem_process_seqs] Processed 721850 reads in 132.360 CPU sec, 4.299 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 296546, 41, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 370, 1110)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2906)
[M::mem_pestat] mean and std.dev: (656.70, 617.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3804)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 193, 279)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 567)
[M::mem_pestat] mean and std.dev: (214.91, 103.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 711)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 639, 1666)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4580)
[M::mem_pestat] mean and std.dev: (961.60, 975.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6037)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 496, 1445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3879)
[M::mem_pestat] mean and std.dev: (763.61, 779.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5096)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 83, #reads = 1093002 mem = 536880557 peak = 1000341504
[M::process] read 721940 sequences (100000273 bp) in 3.015 CPU sec, 3.190 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 296691, 41, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (260, 637, 1311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3413)
[M::mem_pestat] mean and std.dev: (742.30, 614.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4464)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 193, 279)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 567)
[M::mem_pestat] mean and std.dev: (214.93, 103.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 711)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (312, 596, 1557)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4047)
[M::mem_pestat] mean and std.dev: (993.73, 874.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5292)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 285, 632)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1556)
[M::mem_pestat] mean and std.dev: (370.59, 283.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2018)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722432 sequences (100000221 bp) in 1.990 CPU sec, 2.000 real sec...
[M::mem_process_seqs] Processed 721594 reads in 202.044 CPU sec, 6.544 real sec
[M::mem_process_seqs] Processed 721772 reads in 134.011 CPU sec, 4.266 real sec
sorting block 84, #reads = 1093128 mem = 536878353 peak = 1000341504
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 296505, 44, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 277, 675)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1611)
[M::mem_pestat] mean and std.dev: (417.96, 370.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2079)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 192, 277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 561)
[M::mem_pestat] mean and std.dev: (213.93, 102.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 703)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (297, 651, 1019)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2463)
[M::mem_pestat] mean and std.dev: (729.93, 594.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3185)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 349, 1484)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4066)
[M::mem_pestat] mean and std.dev: (852.50, 920.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5357)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722136 sequences (100000093 bp) in 2.429 CPU sec, 2.546 real sec...
[M::process] read 721692 sequences (100000146 bp) in 2.100 CPU sec, 2.108 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 296837, 34, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 425, 1690)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4644)
[M::mem_pestat] mean and std.dev: (627.96, 633.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6121)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 192, 277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 561)
[M::mem_pestat] mean and std.dev: (213.60, 102.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 703)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 419, 774)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1900)
[M::mem_pestat] mean and std.dev: (417.45, 394.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2463)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 418, 1202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3106)
[M::mem_pestat] mean and std.dev: (809.05, 767.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4058)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 721940 reads in 197.779 CPU sec, 6.325 real sec
[M::mem_process_seqs] Processed 722432 reads in 132.997 CPU sec, 4.256 real sec
sorting block 85, #reads = 1093645 mem = 536881248 peak = 1000341504
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 296342, 35, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 415, 915)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2319)
[M::mem_pestat] mean and std.dev: (547.56, 442.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3021)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 192, 277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 561)
[M::mem_pestat] mean and std.dev: (213.61, 102.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 703)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (319, 494, 1300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3262)
[M::mem_pestat] mean and std.dev: (659.26, 572.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4243)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 778, 1305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3481)
[M::mem_pestat] mean and std.dev: (710.07, 675.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4569)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720900 sequences (100000267 bp) in 2.805 CPU sec, 2.966 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 296535, 32, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (344, 699, 1209)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2939)
[M::mem_pestat] mean and std.dev: (788.23, 604.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3804)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 193, 278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 564)
[M::mem_pestat] mean and std.dev: (214.24, 102.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 707)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 250, 1117)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3045)
[M::mem_pestat] mean and std.dev: (511.50, 570.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4009)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 309, 709)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1735)
[M::mem_pestat] mean and std.dev: (436.00, 387.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2248)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720714 sequences (100000106 bp) in 1.965 CPU sec, 1.965 real sec...
[M::mem_process_seqs] Processed 722136 reads in 203.512 CPU sec, 6.525 real sec
sorting block 86, #reads = 1092656 mem = 536883830 peak = 1000341504
[M::mem_process_seqs] Processed 721692 reads in 137.020 CPU sec, 4.374 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (88, 295883, 40, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 283, 665)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1589)
[M::mem_pestat] mean and std.dev: (307.73, 213.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2051)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 193, 279)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 565)
[M::mem_pestat] mean and std.dev: (215.29, 103.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 708)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (130, 481, 715)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1885)
[M::mem_pestat] mean and std.dev: (401.67, 349.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2470)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 361, 1114)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2896)
[M::mem_pestat] mean and std.dev: (572.40, 570.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3787)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 87, #reads = 1091875 mem = 536877343 peak = 1035968512
[M::process] read 720108 sequences (100000043 bp) in 2.865 CPU sec, 3.024 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 296860, 59, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 505, 851)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2059)
[M::mem_pestat] mean and std.dev: (599.43, 467.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2663)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 194, 280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 568)
[M::mem_pestat] mean and std.dev: (215.80, 103.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 712)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 514, 1258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3378)
[M::mem_pestat] mean and std.dev: (646.75, 590.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4438)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 332, 976)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2520)
[M::mem_pestat] mean and std.dev: (590.21, 571.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3292)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719992 sequences (100000279 bp) in 2.031 CPU sec, 2.032 real sec...
[M::mem_process_seqs] Processed 720900 reads in 196.006 CPU sec, 6.257 real sec
[M::mem_process_seqs] Processed 720714 reads in 131.499 CPU sec, 4.279 real sec
sorting block 88, #reads = 1092399 mem = 536879353 peak = 1035968512
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 295823, 34, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (297, 505, 770)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1716)
[M::mem_pestat] mean and std.dev: (526.04, 355.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2189)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 195, 281)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 571)
[M::mem_pestat] mean and std.dev: (216.91, 104.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 716)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 507, 1062)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2890)
[M::mem_pestat] mean and std.dev: (591.00, 649.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3804)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 355, 752)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1754)
[M::mem_pestat] mean and std.dev: (475.09, 379.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2255)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720578 sequences (100000243 bp) in 3.011 CPU sec, 3.152 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 296464, 55, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 319, 1117)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3051)
[M::mem_pestat] mean and std.dev: (556.48, 628.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4018)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 195, 282)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 572)
[M::mem_pestat] mean and std.dev: (217.23, 104.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 717)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (308, 617, 1591)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4157)
[M::mem_pestat] mean and std.dev: (836.64, 667.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5440)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (265, 353, 577)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1201)
[M::mem_pestat] mean and std.dev: (350.84, 185.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1513)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720056 sequences (100000100 bp) in 1.986 CPU sec, 1.996 real sec...
[M::mem_process_seqs] Processed 720108 reads in 199.188 CPU sec, 6.453 real sec
[M::mem_process_seqs] Processed 719992 reads in 131.644 CPU sec, 4.174 real sec
sorting block 89, #reads = 1091377 mem = 536879139 peak = 1035968512
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 296270, 40, 87)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 285, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1012)
[M::mem_pestat] mean and std.dev: (292.69, 186.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1291)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 195, 282)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 574)
[M::mem_pestat] mean and std.dev: (217.07, 104.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 720)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 323, 976)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2506)
[M::mem_pestat] mean and std.dev: (484.50, 463.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3271)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (280, 552, 1198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3034)
[M::mem_pestat] mean and std.dev: (740.57, 597.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3952)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725702 sequences (100000101 bp) in 2.905 CPU sec, 3.060 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 295895, 46, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 386, 792)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1896)
[M::mem_pestat] mean and std.dev: (462.24, 361.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2448)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 195, 284)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 580)
[M::mem_pestat] mean and std.dev: (218.13, 105.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 728)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 393, 1180)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3122)
[M::mem_pestat] mean and std.dev: (607.14, 643.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4093)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 409, 805)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1933)
[M::mem_pestat] mean and std.dev: (513.11, 433.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2497)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 734008 sequences (100000090 bp) in 2.123 CPU sec, 2.131 real sec...
[M::mem_process_seqs] Processed 720578 reads in 194.686 CPU sec, 6.205 real sec
sorting block 90, #reads = 1092175 mem = 536878288 peak = 1035968512
[M::mem_process_seqs] Processed 720056 reads in 130.650 CPU sec, 4.151 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 297995, 33, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 350, 773)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1853)
[M::mem_pestat] mean and std.dev: (508.83, 459.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2393)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 188, 271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 549)
[M::mem_pestat] mean and std.dev: (209.61, 101.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 688)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 385, 968)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2462)
[M::mem_pestat] mean and std.dev: (573.55, 536.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3209)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 313, 1143)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3055)
[M::mem_pestat] mean and std.dev: (611.81, 656.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4011)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 91, #reads = 1092105 mem = 536880386 peak = 1035968512
[M::process] read 732714 sequences (100000213 bp) in 2.841 CPU sec, 2.957 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 301219, 40, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (246, 437, 1891)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5181)
[M::mem_pestat] mean and std.dev: (795.25, 802.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6826)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (126, 177, 253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 507)
[M::mem_pestat] mean and std.dev: (197.04, 93.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 634)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 692, 2825)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8107)
[M::mem_pestat] mean and std.dev: (1282.89, 1674.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10748)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (277, 362, 1513)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3985)
[M::mem_pestat] mean and std.dev: (766.42, 727.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5221)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 732324 sequences (100000102 bp) in 2.002 CPU sec, 2.003 real sec...
[M::mem_process_seqs] Processed 725702 reads in 196.897 CPU sec, 6.265 real sec
[M::mem_process_seqs] Processed 734008 reads in 131.962 CPU sec, 4.182 real sec
sorting block 92, #reads = 1095530 mem = 536880291 peak = 1035968512
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 300963, 29, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 273, 833)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2181)
[M::mem_pestat] mean and std.dev: (547.92, 581.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2875)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 179, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 514)
[M::mem_pestat] mean and std.dev: (199.26, 95.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 643)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 329, 1030)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2740)
[M::mem_pestat] mean and std.dev: (509.81, 530.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3595)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 345, 1116)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2934)
[M::mem_pestat] mean and std.dev: (503.81, 509.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3843)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 731330 sequences (100000079 bp) in 3.066 CPU sec, 3.182 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 300987, 28, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 439, 915)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2403)
[M::mem_pestat] mean and std.dev: (498.73, 433.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3147)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 179, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 514)
[M::mem_pestat] mean and std.dev: (199.59, 95.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 643)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (289, 788, 1314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3364)
[M::mem_pestat] mean and std.dev: (759.44, 677.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4389)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 335, 1341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3617)
[M::mem_pestat] mean and std.dev: (780.64, 853.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4755)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 730670 sequences (100000018 bp) in 2.115 CPU sec, 2.122 real sec...
[M::mem_process_seqs] Processed 732714 reads in 196.744 CPU sec, 6.247 real sec
[M::mem_process_seqs] Processed 732324 reads in 130.885 CPU sec, 4.141 real sec
sorting block 93, #reads = 1096928 mem = 536885652 peak = 1035968512
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 300387, 29, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 299, 674)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1602)
[M::mem_pestat] mean and std.dev: (383.89, 279.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2066)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 180, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 521)
[M::mem_pestat] mean and std.dev: (201.25, 96.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 652)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 723, 1224)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3176)
[M::mem_pestat] mean and std.dev: (791.31, 662.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4152)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (264, 538, 1501)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3975)
[M::mem_pestat] mean and std.dev: (680.75, 614.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5212)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 729754 sequences (100000087 bp) in 2.870 CPU sec, 2.996 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 300593, 46, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 475, 1374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3760)
[M::mem_pestat] mean and std.dev: (678.00, 627.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4953)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 181, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 525)
[M::mem_pestat] mean and std.dev: (202.51, 97.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 657)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 652, 1804)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5048)
[M::mem_pestat] mean and std.dev: (1129.93, 1346.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6670)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (309, 439, 808)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1806)
[M::mem_pestat] mean and std.dev: (495.67, 350.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2305)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728598 sequences (100000091 bp) in 2.034 CPU sec, 2.044 real sec...
[M::mem_process_seqs] Processed 731330 reads in 193.041 CPU sec, 6.146 real sec
sorting block 94, #reads = 1098047 mem = 536883398 peak = 1035968512
[M::mem_process_seqs] Processed 730670 reads in 131.396 CPU sec, 4.172 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 300049, 38, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 323, 556)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1362)
[M::mem_pestat] mean and std.dev: (349.57, 253.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1765)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 182, 263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 531)
[M::mem_pestat] mean and std.dev: (204.01, 98.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 665)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (96, 326, 845)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2343)
[M::mem_pestat] mean and std.dev: (418.26, 416.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3092)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 423, 1294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3388)
[M::mem_pestat] mean and std.dev: (824.76, 878.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4435)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 95, #reads = 1096779 mem = 536881299 peak = 1035968512
[M::process] read 727786 sequences (100000007 bp) in 2.865 CPU sec, 2.987 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 299354, 42, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (254, 674, 2743)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7721)
[M::mem_pestat] mean and std.dev: (1626.19, 1865.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10210)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 184, 267)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 541)
[M::mem_pestat] mean and std.dev: (206.71, 100.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 678)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (95, 585, 2078)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6044)
[M::mem_pestat] mean and std.dev: (840.69, 904.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8027)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 675, 1116)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2896)
[M::mem_pestat] mean and std.dev: (674.10, 509.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3786)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727632 sequences (100000008 bp) in 2.060 CPU sec, 2.058 real sec...
[M::mem_process_seqs] Processed 729754 reads in 193.566 CPU sec, 6.165 real sec
[M::mem_process_seqs] Processed 728598 reads in 127.355 CPU sec, 4.346 real sec
sorting block 96, #reads = 1095223 mem = 536876607 peak = 1035968512
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 299688, 30, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (299, 520, 1272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3218)
[M::mem_pestat] mean and std.dev: (783.85, 688.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4191)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 186, 271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 551)
[M::mem_pestat] mean and std.dev: (209.17, 102.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 691)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (487, 717, 911)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1759)
[M::mem_pestat] mean and std.dev: (607.52, 308.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2183)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (403, 618, 1505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3709)
[M::mem_pestat] mean and std.dev: (764.22, 516.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4811)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727576 sequences (100000069 bp) in 2.792 CPU sec, 2.929 real sec...
[M::process] read 728942 sequences (100000206 bp) in 2.060 CPU sec, 2.059 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 299535, 44, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 316, 840)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2206)
[M::mem_pestat] mean and std.dev: (459.21, 404.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2889)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 185, 270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 548)
[M::mem_pestat] mean and std.dev: (208.85, 102.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 687)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (85, 383, 928)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2614)
[M::mem_pestat] mean and std.dev: (467.98, 506.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3457)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 432, 1003)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2561)
[M::mem_pestat] mean and std.dev: (452.08, 316.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3340)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 727786 reads in 195.427 CPU sec, 6.510 real sec
[M::mem_process_seqs] Processed 727632 reads in 125.637 CPU sec, 4.111 real sec
sorting block 97, #reads = 1094273 mem = 536879028 peak = 1035968512
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 299614, 39, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 629, 2282)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6390)
[M::mem_pestat] mean and std.dev: (1438.90, 1751.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8446)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 186, 270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 548)
[M::mem_pestat] mean and std.dev: (208.80, 102.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 687)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (419, 664, 1100)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2462)
[M::mem_pestat] mean and std.dev: (664.26, 491.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3143)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 379, 499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1089)
[M::mem_pestat] mean and std.dev: (343.31, 176.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1384)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 730274 sequences (100000080 bp) in 2.825 CPU sec, 2.920 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 299821, 35, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (281, 540, 1404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3650)
[M::mem_pestat] mean and std.dev: (697.75, 577.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4773)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 183, 264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 532)
[M::mem_pestat] mean and std.dev: (204.77, 98.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 666)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 510, 993)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2601)
[M::mem_pestat] mean and std.dev: (558.71, 549.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3405)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 451, 1424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3888)
[M::mem_pestat] mean and std.dev: (738.12, 746.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5120)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 730060 sequences (100000184 bp) in 2.090 CPU sec, 2.092 real sec...
[M::mem_process_seqs] Processed 727576 reads in 190.072 CPU sec, 6.160 real sec
sorting block 98, #reads = 1096849 mem = 536879400 peak = 1035968512
[M::mem_process_seqs] Processed 728942 reads in 122.869 CPU sec, 3.924 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 300401, 43, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (270, 539, 788)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1824)
[M::mem_pestat] mean and std.dev: (461.72, 297.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2342)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 181, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 525)
[M::mem_pestat] mean and std.dev: (202.75, 97.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 657)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 471, 1439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4031)
[M::mem_pestat] mean and std.dev: (704.42, 728.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5327)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (260, 558, 1497)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3971)
[M::mem_pestat] mean and std.dev: (848.77, 764.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5208)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 99, #reads = 1096132 mem = 536878058 peak = 1035968512
[M::process] read 729870 sequences (100000086 bp) in 2.870 CPU sec, 2.944 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 299453, 33, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 276, 642)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1624)
[M::mem_pestat] mean and std.dev: (377.11, 313.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2115)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 181, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 525)
[M::mem_pestat] mean and std.dev: (202.47, 97.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 657)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (310, 739, 1822)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4846)
[M::mem_pestat] mean and std.dev: (1097.26, 1169.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6358)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (263, 615, 1504)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3986)
[M::mem_pestat] mean and std.dev: (810.71, 763.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5227)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 730148 sequences (100000155 bp) in 2.100 CPU sec, 2.104 real sec...
[M::mem_process_seqs] Processed 730274 reads in 197.672 CPU sec, 6.300 real sec
[M::mem_process_seqs] Processed 730060 reads in 130.202 CPU sec, 4.125 real sec
sorting block 100, #reads = 1094030 mem = 536878728 peak = 1035968512
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (83, 299731, 54, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (246, 409, 936)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2316)
[M::mem_pestat] mean and std.dev: (490.03, 395.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3006)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 182, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 525)
[M::mem_pestat] mean and std.dev: (202.90, 97.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 657)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 602, 1629)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4357)
[M::mem_pestat] mean and std.dev: (907.87, 909.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5721)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 264, 672)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1586)
[M::mem_pestat] mean and std.dev: (482.27, 397.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2072)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 729844 sequences (100000232 bp) in 2.882 CPU sec, 2.956 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 300032, 38, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 305, 414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 908)
[M::mem_pestat] mean and std.dev: (304.35, 168.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1155)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 181, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 525)
[M::mem_pestat] mean and std.dev: (202.60, 97.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 657)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 433, 1233)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3307)
[M::mem_pestat] mean and std.dev: (762.95, 696.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4344)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 469, 1075)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2771)
[M::mem_pestat] mean and std.dev: (695.90, 699.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3619)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727960 sequences (100000276 bp) in 2.130 CPU sec, 2.131 real sec...
[M::mem_process_seqs] Processed 729870 reads in 199.292 CPU sec, 6.427 real sec
[M::mem_process_seqs] Processed 730148 reads in 130.682 CPU sec, 4.144 real sec
sorting block 101, #reads = 1094979 mem = 536877153 peak = 1035968512
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 299557, 30, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 470, 1539)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4265)
[M::mem_pestat] mean and std.dev: (941.57, 1053.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5628)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 182, 262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 528)
[M::mem_pestat] mean and std.dev: (203.18, 97.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 661)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 796, 1360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3658)
[M::mem_pestat] mean and std.dev: (918.59, 997.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4910)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 337, 1503)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4173)
[M::mem_pestat] mean and std.dev: (786.38, 837.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5508)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727264 sequences (100000225 bp) in 2.770 CPU sec, 2.871 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 298815, 38, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 414, 982)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2474)
[M::mem_pestat] mean and std.dev: (535.40, 398.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3220)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 184, 265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 535)
[M::mem_pestat] mean and std.dev: (205.60, 99.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 670)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (259, 599, 1080)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2722)
[M::mem_pestat] mean and std.dev: (600.74, 529.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3543)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 405, 1322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3514)
[M::mem_pestat] mean and std.dev: (817.54, 789.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4610)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726644 sequences (100000074 bp) in 2.079 CPU sec, 2.081 real sec...
[M::mem_process_seqs] Processed 729844 reads in 196.907 CPU sec, 6.280 real sec
sorting block 102, #reads = 1093518 mem = 536877433 peak = 1035968512
[M::mem_process_seqs] Processed 727960 reads in 131.011 CPU sec, 4.265 real sec
sorting block 103, #reads = 1092161 mem = 536882570 peak = 1046953984
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 298851, 40, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 266, 687)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1721)
[M::mem_pestat] mean and std.dev: (421.68, 420.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2238)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 185, 267)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 539)
[M::mem_pestat] mean and std.dev: (206.69, 99.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 675)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (90, 276, 1444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4152)
[M::mem_pestat] mean and std.dev: (785.35, 899.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5506)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 416, 921)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2325)
[M::mem_pestat] mean and std.dev: (647.89, 543.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3027)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727894 sequences (100000154 bp) in 2.855 CPU sec, 2.945 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 299044, 45, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 363, 785)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2037)
[M::mem_pestat] mean and std.dev: (397.04, 366.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2663)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 186, 269)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 545)
[M::mem_pestat] mean and std.dev: (208.35, 100.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 683)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 491, 858)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2178)
[M::mem_pestat] mean and std.dev: (544.29, 376.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2838)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 488, 1221)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3167)
[M::mem_pestat] mean and std.dev: (715.59, 621.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4140)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 731836 sequences (100000249 bp) in 2.190 CPU sec, 2.184 real sec...
[M::mem_process_seqs] Processed 727264 reads in 194.685 CPU sec, 6.284 real sec
[M::mem_process_seqs] Processed 726644 reads in 128.357 CPU sec, 4.095 real sec
sorting block 104, #reads = 1094512 mem = 536879988 peak = 1046953984
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 298374, 38, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 381, 1046)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2844)
[M::mem_pestat] mean and std.dev: (627.06, 630.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3743)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 184, 266)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 538)
[M::mem_pestat] mean and std.dev: (206.10, 99.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 674)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (346, 728, 928)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2092)
[M::mem_pestat] mean and std.dev: (699.39, 456.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2674)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 353, 1049)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2767)
[M::mem_pestat] mean and std.dev: (606.64, 622.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3626)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727918 sequences (100000159 bp) in 2.891 CPU sec, 2.967 real sec...
[M::process] read 726898 sequences (100000222 bp) in 2.150 CPU sec, 2.146 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 299411, 53, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 249, 998)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2686)
[M::mem_pestat] mean and std.dev: (546.46, 603.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3530)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 180, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 521)
[M::mem_pestat] mean and std.dev: (201.14, 96.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 652)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (310, 739, 1747)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4621)
[M::mem_pestat] mean and std.dev: (1014.00, 1018.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6058)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 429, 1024)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2592)
[M::mem_pestat] mean and std.dev: (616.67, 557.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3376)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 727894 reads in 212.626 CPU sec, 6.785 real sec
[M::mem_process_seqs] Processed 731836 reads in 151.550 CPU sec, 4.831 real sec
sorting block 105, #reads = 1092358 mem = 536887935 peak = 1046953984
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 298783, 43, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 441, 1045)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2667)
[M::mem_pestat] mean and std.dev: (619.22, 536.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3478)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 184, 266)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 538)
[M::mem_pestat] mean and std.dev: (206.07, 99.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 674)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 681, 1032)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2706)
[M::mem_pestat] mean and std.dev: (726.02, 625.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3543)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 336, 767)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1861)
[M::mem_pestat] mean and std.dev: (417.63, 336.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2408)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725510 sequences (100000230 bp) in 2.819 CPU sec, 2.884 real sec...
[M::process] read 725232 sequences (100000110 bp) in 2.100 CPU sec, 2.107 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 297872, 54, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 433, 1605)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4357)
[M::mem_pestat] mean and std.dev: (913.77, 980.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5733)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 186, 268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 542)
[M::mem_pestat] mean and std.dev: (207.41, 99.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 679)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (104, 464, 1451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4145)
[M::mem_pestat] mean and std.dev: (674.84, 727.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5492)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 502, 1469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3955)
[M::mem_pestat] mean and std.dev: (756.59, 761.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5198)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 727918 reads in 209.577 CPU sec, 6.677 real sec
sorting block 106, #reads = 1082584 mem = 536882047 peak = 1046953984
[M::mem_process_seqs] Processed 726898 reads in 140.132 CPU sec, 4.469 real sec
sorting block 107, #reads = 1087059 mem = 536877498 peak = 1046953984
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 297136, 40, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 571, 1497)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4151)
[M::mem_pestat] mean and std.dev: (775.34, 855.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5478)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 188, 270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 546)
[M::mem_pestat] mean and std.dev: (209.13, 100.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 684)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (533, 998, 1758)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4208)
[M::mem_pestat] mean and std.dev: (1231.30, 960.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5433)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 392, 1608)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4458)
[M::mem_pestat] mean and std.dev: (924.29, 1010.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5883)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725346 sequences (100000075 bp) in 2.699 CPU sec, 2.882 real sec...
[M::process] read 724586 sequences (100000149 bp) in 2.060 CPU sec, 2.061 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 297834, 47, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 672, 1939)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5351)
[M::mem_pestat] mean and std.dev: (729.61, 677.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7057)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 188, 271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 549)
[M::mem_pestat] mean and std.dev: (209.80, 101.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 688)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 449, 1423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3911)
[M::mem_pestat] mean and std.dev: (840.65, 899.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5155)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 721, 1144)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3026)
[M::mem_pestat] mean and std.dev: (684.40, 571.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3967)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 725510 reads in 206.883 CPU sec, 6.602 real sec
[M::mem_process_seqs] Processed 725232 reads in 137.543 CPU sec, 4.476 real sec
sorting block 108, #reads = 1087116 mem = 536880066 peak = 1046953984
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 297706, 38, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 311, 1150)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3040)
[M::mem_pestat] mean and std.dev: (743.00, 741.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3985)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 187, 270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 546)
[M::mem_pestat] mean and std.dev: (209.41, 101.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 684)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (336, 819, 1869)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4935)
[M::mem_pestat] mean and std.dev: (1123.50, 996.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6468)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (274, 415, 1413)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3691)
[M::mem_pestat] mean and std.dev: (837.35, 810.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4830)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724818 sequences (100000143 bp) in 2.889 CPU sec, 2.979 real sec...
[M::process] read 725166 sequences (100000192 bp) in 1.990 CPU sec, 1.993 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 297892, 31, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 368, 764)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1966)
[M::mem_pestat] mean and std.dev: (453.10, 394.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2567)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 188, 272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 550)
[M::mem_pestat] mean and std.dev: (210.46, 101.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 689)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 349, 846)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2184)
[M::mem_pestat] mean and std.dev: (446.07, 449.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2853)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 334, 622)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1532)
[M::mem_pestat] mean and std.dev: (378.34, 323.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1987)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 725346 reads in 207.802 CPU sec, 6.709 real sec
[M::mem_process_seqs] Processed 724586 reads in 135.894 CPU sec, 4.460 real sec
sorting block 109, #reads = 1088429 mem = 536880416 peak = 1046953984
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 297585, 28, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 243, 568)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1400)
[M::mem_pestat] mean and std.dev: (329.46, 265.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1816)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 187, 271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 547)
[M::mem_pestat] mean and std.dev: (209.41, 101.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 685)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (96, 746, 1904)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5520)
[M::mem_pestat] mean and std.dev: (1004.81, 1069.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7328)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 305, 1064)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2820)
[M::mem_pestat] mean and std.dev: (581.93, 581.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3698)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724670 sequences (100000124 bp) in 2.799 CPU sec, 2.890 real sec...
[M::process] read 733780 sequences (100000097 bp) in 2.028 CPU sec, 2.032 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 297588, 43, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (266, 517, 1988)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5432)
[M::mem_pestat] mean and std.dev: (909.56, 1106.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7154)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 187, 269)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 543)
[M::mem_pestat] mean and std.dev: (208.58, 100.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 680)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 354, 1027)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2689)
[M::mem_pestat] mean and std.dev: (529.10, 530.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3520)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (266, 455, 1004)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2480)
[M::mem_pestat] mean and std.dev: (655.50, 583.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3218)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724818 reads in 210.495 CPU sec, 6.841 real sec
sorting block 110, #reads = 1090181 mem = 536881430 peak = 1046953984
[M::mem_process_seqs] Processed 725166 reads in 142.378 CPU sec, 4.548 real sec
sorting block 111, #reads = 1086935 mem = 536880208 peak = 1096388608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 297424, 45, 94)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 371, 1170)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3092)
[M::mem_pestat] mean and std.dev: (563.19, 529.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4053)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 188, 270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 544)
[M::mem_pestat] mean and std.dev: (209.38, 100.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 681)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 341, 947)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2517)
[M::mem_pestat] mean and std.dev: (433.05, 477.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3302)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (267, 627, 1443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3795)
[M::mem_pestat] mean and std.dev: (781.80, 843.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4971)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 739312 sequences (100000110 bp) in 2.935 CPU sec, 2.980 real sec...
[M::process] read 734436 sequences (100000011 bp) in 1.720 CPU sec, 1.724 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 300584, 42, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 532, 1270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3282)
[M::mem_pestat] mean and std.dev: (841.72, 804.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4288)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (126, 178, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 510)
[M::mem_pestat] mean and std.dev: (197.56, 93.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 638)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 518, 1106)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3014)
[M::mem_pestat] mean and std.dev: (782.51, 777.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3968)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 462, 1285)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3459)
[M::mem_pestat] mean and std.dev: (668.52, 585.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4546)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724670 reads in 212.341 CPU sec, 6.761 real sec
[M::mem_process_seqs] Processed 733780 reads in 146.638 CPU sec, 4.675 real sec
sorting block 112, #reads = 1085845 mem = 536878914 peak = 1096388608
[M::process] read 732876 sequences (100000075 bp) in 2.961 CPU sec, 3.035 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 303019, 38, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 229, 630)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1610)
[M::mem_pestat] mean and std.dev: (420.13, 365.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2100)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (123, 172, 244)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 486)
[M::mem_pestat] mean and std.dev: (190.72, 89.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 607)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 675, 1308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3464)
[M::mem_pestat] mean and std.dev: (894.69, 917.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4564)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 374, 712)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1678)
[M::mem_pestat] mean and std.dev: (424.54, 296.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2161)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 731918 sequences (100000004 bp) in 1.678 CPU sec, 1.677 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 301616, 46, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 630, 1144)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3022)
[M::mem_pestat] mean and std.dev: (673.73, 623.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3961)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (126, 176, 252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 504)
[M::mem_pestat] mean and std.dev: (196.35, 93.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 630)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (426, 739, 997)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2139)
[M::mem_pestat] mean and std.dev: (773.50, 478.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2710)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 455, 910)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2266)
[M::mem_pestat] mean and std.dev: (578.23, 510.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2944)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 739312 reads in 220.849 CPU sec, 7.043 real sec
sorting block 113, #reads = 1088018 mem = 536882400 peak = 1096388608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 300693, 41, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 320, 746)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1848)
[M::mem_pestat] mean and std.dev: (395.62, 310.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2399)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 178, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 514)
[M::mem_pestat] mean and std.dev: (199.35, 95.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 643)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 688, 1171)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3059)
[M::mem_pestat] mean and std.dev: (712.70, 559.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4003)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 495, 1170)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3138)
[M::mem_pestat] mean and std.dev: (617.68, 586.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4122)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 734436 reads in 230.292 CPU sec, 7.320 real sec
[M::process] read 732214 sequences (100000037 bp) in 2.551 CPU sec, 2.568 real sec...
[M::mem_process_seqs] Processed 732876 reads in 253.322 CPU sec, 8.316 real sec
sorting block 114, #reads = 1089920 mem = 536882573 peak = 1096388608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 300735, 38, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 471, 1433)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3899)
[M::mem_pestat] mean and std.dev: (655.38, 524.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5132)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 179, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 518)
[M::mem_pestat] mean and std.dev: (200.32, 95.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 648)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (594, 630, 1124)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2184)
[M::mem_pestat] mean and std.dev: (713.11, 471.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2714)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 309, 730)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1698)
[M::mem_pestat] mean and std.dev: (461.05, 335.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2182)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 729736 sequences (100000192 bp) in 2.974 CPU sec, 3.156 real sec...
[M::process] read 729470 sequences (100000143 bp) in 2.110 CPU sec, 2.108 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 300436, 26, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 396, 1101)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2913)
[M::mem_pestat] mean and std.dev: (642.03, 652.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3819)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 180, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 521)
[M::mem_pestat] mean and std.dev: (201.04, 97.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 652)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (75, 463, 1047)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2991)
[M::mem_pestat] mean and std.dev: (556.83, 631.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3963)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 388, 842)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2126)
[M::mem_pestat] mean and std.dev: (487.88, 420.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2768)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 731918 reads in 213.001 CPU sec, 7.016 real sec
sorting block 115, #reads = 1092742 mem = 536881295 peak = 1096388608
[M::mem_process_seqs] Processed 732214 reads in 141.401 CPU sec, 4.489 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 300727, 40, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 309, 934)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2466)
[M::mem_pestat] mean and std.dev: (507.98, 494.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3232)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 183, 264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 534)
[M::mem_pestat] mean and std.dev: (204.84, 99.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 669)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 349, 1437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3985)
[M::mem_pestat] mean and std.dev: (649.69, 803.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5259)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 332, 806)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2090)
[M::mem_pestat] mean and std.dev: (506.39, 485.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2732)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 116, #reads = 1091278 mem = 536879796 peak = 1096388608
[M::process] read 727930 sequences (100000060 bp) in 3.001 CPU sec, 3.183 real sec...
[M::process] read 727456 sequences (100000058 bp) in 1.940 CPU sec, 1.946 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 299916, 27, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (277, 431, 1067)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2647)
[M::mem_pestat] mean and std.dev: (623.49, 539.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3437)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 183, 264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 532)
[M::mem_pestat] mean and std.dev: (204.78, 99.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 666)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 315, 836)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2146)
[M::mem_pestat] mean and std.dev: (445.04, 399.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2801)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (270, 866, 1766)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4758)
[M::mem_pestat] mean and std.dev: (1011.80, 901.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6254)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 729736 reads in 203.700 CPU sec, 6.611 real sec
[M::mem_process_seqs] Processed 729470 reads in 133.006 CPU sec, 4.226 real sec
sorting block 117, #reads = 1093083 mem = 536880969 peak = 1096388608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 300018, 43, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 455, 743)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1915)
[M::mem_pestat] mean and std.dev: (449.62, 348.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2501)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 185, 268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 542)
[M::mem_pestat] mean and std.dev: (207.60, 101.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 679)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 479, 1226)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3360)
[M::mem_pestat] mean and std.dev: (652.66, 636.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4427)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (321, 400, 612)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1194)
[M::mem_pestat] mean and std.dev: (458.02, 259.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1496)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 729018 sequences (100000182 bp) in 2.806 CPU sec, 2.935 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 299389, 42, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 400, 928)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2326)
[M::mem_pestat] mean and std.dev: (555.23, 457.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3025)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 185, 268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 542)
[M::mem_pestat] mean and std.dev: (207.63, 100.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 679)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 499, 2252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6322)
[M::mem_pestat] mean and std.dev: (1147.39, 1493.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8357)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 370, 877)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2235)
[M::mem_pestat] mean and std.dev: (537.13, 476.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2914)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 729256 sequences (100000115 bp) in 1.990 CPU sec, 1.994 real sec...
[M::mem_process_seqs] Processed 727930 reads in 193.725 CPU sec, 6.160 real sec
[M::mem_process_seqs] Processed 727456 reads in 127.230 CPU sec, 4.334 real sec
sorting block 118, #reads = 1092127 mem = 536880367 peak = 1096388608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 299844, 42, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (316, 465, 1337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3379)
[M::mem_pestat] mean and std.dev: (812.41, 664.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4400)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 183, 263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 529)
[M::mem_pestat] mean and std.dev: (204.05, 98.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 662)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 623, 1475)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4109)
[M::mem_pestat] mean and std.dev: (820.18, 947.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5426)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 609, 1534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4148)
[M::mem_pestat] mean and std.dev: (824.86, 700.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5455)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728960 sequences (100000016 bp) in 2.871 CPU sec, 2.999 real sec...
[M::process] read 728300 sequences (100000146 bp) in 2.050 CPU sec, 2.051 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 299678, 36, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (249, 596, 1207)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3123)
[M::mem_pestat] mean and std.dev: (664.72, 551.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4081)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 182, 263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 529)
[M::mem_pestat] mean and std.dev: (203.78, 97.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 662)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (319, 610, 1723)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4531)
[M::mem_pestat] mean and std.dev: (628.52, 587.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5935)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 352, 695)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1675)
[M::mem_pestat] mean and std.dev: (419.91, 366.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2165)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 729018 reads in 197.631 CPU sec, 6.593 real sec
sorting block 119, #reads = 1093308 mem = 536883971 peak = 1096388608
[M::mem_process_seqs] Processed 729256 reads in 126.806 CPU sec, 4.153 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 299452, 31, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 577, 990)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2496)
[M::mem_pestat] mean and std.dev: (622.60, 458.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3249)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 183, 263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 529)
[M::mem_pestat] mean and std.dev: (204.26, 98.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 662)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 578, 959)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2347)
[M::mem_pestat] mean and std.dev: (618.93, 488.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3041)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (264, 394, 720)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1632)
[M::mem_pestat] mean and std.dev: (402.44, 232.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2088)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 120, #reads = 1095183 mem = 536879293 peak = 1096388608
[M::process] read 727926 sequences (100000111 bp) in 2.746 CPU sec, 2.854 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 300064, 56, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 318, 1882)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5282)
[M::mem_pestat] mean and std.dev: (830.22, 939.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6982)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 184, 264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 532)
[M::mem_pestat] mean and std.dev: (205.07, 98.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 666)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (520, 968, 1395)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3145)
[M::mem_pestat] mean and std.dev: (922.39, 595.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4020)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 364, 773)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1871)
[M::mem_pestat] mean and std.dev: (459.96, 333.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2420)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728144 sequences (100000008 bp) in 2.090 CPU sec, 2.085 real sec...
[M::mem_process_seqs] Processed 728960 reads in 189.297 CPU sec, 6.115 real sec
[M::mem_process_seqs] Processed 728300 reads in 120.993 CPU sec, 3.830 real sec
sorting block 121, #reads = 1094416 mem = 536879012 peak = 1096388608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 298932, 33, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 383, 810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2032)
[M::mem_pestat] mean and std.dev: (539.25, 448.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2643)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 184, 266)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 538)
[M::mem_pestat] mean and std.dev: (206.23, 99.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 674)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 770, 1026)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2770)
[M::mem_pestat] mean and std.dev: (626.45, 565.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3642)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (278, 609, 1212)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3080)
[M::mem_pestat] mean and std.dev: (659.86, 587.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4014)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728022 sequences (100000129 bp) in 2.883 CPU sec, 2.992 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 298963, 44, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 644, 915)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2275)
[M::mem_pestat] mean and std.dev: (631.02, 533.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2955)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 183, 264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 532)
[M::mem_pestat] mean and std.dev: (204.78, 98.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 666)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (391, 1018, 1485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3673)
[M::mem_pestat] mean and std.dev: (873.05, 706.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4767)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 439, 1241)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3215)
[M::mem_pestat] mean and std.dev: (638.80, 567.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4202)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727642 sequences (100000210 bp) in 2.090 CPU sec, 2.086 real sec...
[M::mem_process_seqs] Processed 727926 reads in 191.277 CPU sec, 6.073 real sec
[M::mem_process_seqs] Processed 728144 reads in 127.339 CPU sec, 4.035 real sec
sorting block 122, #reads = 1094034 mem = 536878947 peak = 1096388608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 298587, 30, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 299, 727)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1825)
[M::mem_pestat] mean and std.dev: (471.57, 425.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2374)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 184, 265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 535)
[M::mem_pestat] mean and std.dev: (205.36, 98.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 670)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (460, 729, 1452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3436)
[M::mem_pestat] mean and std.dev: (1045.47, 882.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4576)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 344, 735)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1801)
[M::mem_pestat] mean and std.dev: (422.17, 326.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2334)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728490 sequences (100000150 bp) in 2.867 CPU sec, 2.968 real sec...
[M::process] read 730784 sequences (100000189 bp) in 2.130 CPU sec, 2.126 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 298923, 38, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 292, 1090)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2880)
[M::mem_pestat] mean and std.dev: (551.50, 630.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3775)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 184, 266)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 538)
[M::mem_pestat] mean and std.dev: (206.21, 99.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 674)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 591, 2015)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5637)
[M::mem_pestat] mean and std.dev: (881.49, 889.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7448)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (258, 410, 1465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3879)
[M::mem_pestat] mean and std.dev: (768.19, 750.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5086)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 728022 reads in 208.520 CPU sec, 6.929 real sec
sorting block 123, #reads = 1091430 mem = 536884534 peak = 1096388608
[M::mem_process_seqs] Processed 727642 reads in 136.437 CPU sec, 4.350 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 298776, 44, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 455, 1413)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3791)
[M::mem_pestat] mean and std.dev: (703.08, 719.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4980)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
sorting block 124, #reads = 1090310 mem = 536879726 peak = 1096388608
[M::mem_pestat] (25, 50, 75) percentile: (130, 183, 264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 532)
[M::mem_pestat] mean and std.dev: (204.82, 98.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 666)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (261, 579, 1200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3078)
[M::mem_pestat] mean and std.dev: (695.95, 695.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4017)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 313, 525)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1139)
[M::mem_pestat] mean and std.dev: (302.34, 160.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1446)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724992 sequences (100000045 bp) in 2.780 CPU sec, 2.889 real sec...
[M::process] read 724560 sequences (100000096 bp) in 2.050 CPU sec, 2.050 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 299173, 54, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 393, 966)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2542)
[M::mem_pestat] mean and std.dev: (538.64, 508.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3330)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 181, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 522)
[M::mem_pestat] mean and std.dev: (201.85, 96.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 653)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 984, 2072)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5810)
[M::mem_pestat] mean and std.dev: (1335.52, 1461.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7679)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 320, 697)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1657)
[M::mem_pestat] mean and std.dev: (384.28, 278.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2137)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 728490 reads in 211.220 CPU sec, 6.724 real sec
[M::mem_process_seqs] Processed 730784 reads in 148.279 CPU sec, 4.736 real sec
sorting block 125, #reads = 1083732 mem = 536885371 peak = 1096388608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 298046, 39, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 277, 1241)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3383)
[M::mem_pestat] mean and std.dev: (568.39, 711.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4454)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 187, 270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 544)
[M::mem_pestat] mean and std.dev: (209.11, 100.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 681)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (302, 467, 889)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2063)
[M::mem_pestat] mean and std.dev: (485.09, 382.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2650)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 292, 899)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2373)
[M::mem_pestat] mean and std.dev: (535.68, 504.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3110)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724900 sequences (100000142 bp) in 2.508 CPU sec, 2.652 real sec...
[M::process] read 724226 sequences (100000073 bp) in 1.560 CPU sec, 1.560 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 297434, 40, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 626, 1270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3354)
[M::mem_pestat] mean and std.dev: (809.29, 756.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4396)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 188, 271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 547)
[M::mem_pestat] mean and std.dev: (209.69, 101.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 685)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 615, 2035)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5611)
[M::mem_pestat] mean and std.dev: (1097.67, 1186.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7399)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (272, 777, 1562)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4142)
[M::mem_pestat] mean and std.dev: (867.94, 692.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5432)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724992 reads in 186.866 CPU sec, 5.978 real sec
[M::mem_process_seqs] Processed 724560 reads in 126.289 CPU sec, 4.179 real sec
sorting block 126, #reads = 1089096 mem = 536884478 peak = 1096388608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 297286, 47, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 321, 735)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1841)
[M::mem_pestat] mean and std.dev: (492.57, 455.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2394)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 187, 270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 544)
[M::mem_pestat] mean and std.dev: (209.07, 100.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 681)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 545, 2161)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6129)
[M::mem_pestat] mean and std.dev: (1040.82, 1298.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8113)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 331, 828)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2184)
[M::mem_pestat] mean and std.dev: (483.14, 464.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2862)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724144 sequences (100000207 bp) in 2.685 CPU sec, 2.800 real sec...
[M::process] read 724148 sequences (100000035 bp) in 1.670 CPU sec, 1.662 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 297795, 33, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 480, 1120)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2910)
[M::mem_pestat] mean and std.dev: (627.51, 584.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3805)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 188, 272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 550)
[M::mem_pestat] mean and std.dev: (210.23, 101.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 689)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (378, 723, 1504)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3756)
[M::mem_pestat] mean and std.dev: (813.77, 687.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4882)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (307, 515, 1193)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2965)
[M::mem_pestat] mean and std.dev: (660.10, 600.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3851)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724900 reads in 191.055 CPU sec, 6.232 real sec
sorting block 127, #reads = 1092019 mem = 536877320 peak = 1096388608
[M::mem_process_seqs] Processed 724226 reads in 120.843 CPU sec, 3.956 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 297107, 25, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 569, 925)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2363)
[M::mem_pestat] mean and std.dev: (569.65, 446.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3082)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 188, 272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 550)
[M::mem_pestat] mean and std.dev: (210.43, 102.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 689)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 440, 1711)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4809)
[M::mem_pestat] mean and std.dev: (747.58, 747.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6358)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (335, 681, 1466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3728)
[M::mem_pestat] mean and std.dev: (871.58, 745.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4859)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 128, #reads = 1090623 mem = 536879003 peak = 1096388608
[M::process] read 724018 sequences (100000058 bp) in 2.699 CPU sec, 2.801 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 297134, 40, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 374, 837)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2079)
[M::mem_pestat] mean and std.dev: (502.87, 437.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2700)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 188, 272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 550)
[M::mem_pestat] mean and std.dev: (210.50, 102.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 689)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (465, 857, 1968)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4974)
[M::mem_pestat] mean and std.dev: (1153.13, 932.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6477)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 372, 930)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2386)
[M::mem_pestat] mean and std.dev: (564.90, 521.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3114)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724080 sequences (100000045 bp) in 1.980 CPU sec, 1.971 real sec...
[M::mem_process_seqs] Processed 724144 reads in 189.216 CPU sec, 6.121 real sec
[M::mem_process_seqs] Processed 724148 reads in 124.672 CPU sec, 3.991 real sec
sorting block 129, #reads = 1091407 mem = 536880896 peak = 1096388608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 297361, 58, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (359, 874, 1056)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2450)
[M::mem_pestat] mean and std.dev: (690.02, 515.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3147)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 188, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 556)
[M::mem_pestat] mean and std.dev: (211.39, 103.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 697)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 520, 1796)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4968)
[M::mem_pestat] mean and std.dev: (760.72, 725.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6554)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 486, 1030)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2656)
[M::mem_pestat] mean and std.dev: (611.83, 525.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3469)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723558 sequences (100000116 bp) in 2.895 CPU sec, 2.995 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 297235, 25, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 324, 826)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2046)
[M::mem_pestat] mean and std.dev: (420.77, 321.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2656)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 189, 273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 553)
[M::mem_pestat] mean and std.dev: (210.89, 102.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 693)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 517, 1136)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3018)
[M::mem_pestat] mean and std.dev: (704.17, 729.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3959)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 703, 1671)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4681)
[M::mem_pestat] mean and std.dev: (1036.45, 1028.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6186)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727272 sequences (100000281 bp) in 2.140 CPU sec, 2.146 real sec...
[M::mem_process_seqs] Processed 724018 reads in 190.486 CPU sec, 6.084 real sec
[M::mem_process_seqs] Processed 724080 reads in 125.824 CPU sec, 3.997 real sec
sorting block 130, #reads = 1090116 mem = 536883972 peak = 1096388608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 297189, 64, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 452, 781)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1947)
[M::mem_pestat] mean and std.dev: (565.78, 517.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2634)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 189, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 556)
[M::mem_pestat] mean and std.dev: (211.65, 102.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 697)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (357, 542, 1305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3201)
[M::mem_pestat] mean and std.dev: (790.16, 679.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4149)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 319, 934)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2356)
[M::mem_pestat] mean and std.dev: (506.44, 424.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3067)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 733648 sequences (100000003 bp) in 2.755 CPU sec, 2.847 real sec...
[M::process] read 731046 sequences (100000117 bp) in 2.020 CPU sec, 2.017 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 297581, 53, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 334, 804)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2050)
[M::mem_pestat] mean and std.dev: (461.46, 392.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2673)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 266)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 536)
[M::mem_pestat] mean and std.dev: (205.79, 99.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 671)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (278, 734, 2533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7043)
[M::mem_pestat] mean and std.dev: (1295.31, 1414.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9298)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 536, 1050)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2748)
[M::mem_pestat] mean and std.dev: (643.30, 597.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3597)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723558 reads in 209.867 CPU sec, 6.678 real sec
sorting block 131, #reads = 1090233 mem = 536878448 peak = 1096388608
[M::mem_process_seqs] Processed 727272 reads in 152.377 CPU sec, 4.938 real sec
sorting block 132, #reads = 1080552 mem = 536878770 peak = 1096388608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 300918, 52, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 418, 1033)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2727)
[M::mem_pestat] mean and std.dev: (609.74, 581.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3574)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 177, 253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 505)
[M::mem_pestat] mean and std.dev: (196.98, 93.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 631)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (372, 776, 1546)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3894)
[M::mem_pestat] mean and std.dev: (854.37, 851.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5068)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 378, 769)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1983)
[M::mem_pestat] mean and std.dev: (439.43, 390.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2590)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 730130 sequences (100000111 bp) in 2.622 CPU sec, 2.709 real sec...
[M::process] read 729718 sequences (100000159 bp) in 1.590 CPU sec, 1.591 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 300133, 31, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 345, 871)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2287)
[M::mem_pestat] mean and std.dev: (496.62, 537.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2995)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 180, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 524)
[M::mem_pestat] mean and std.dev: (201.57, 97.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 656)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (98, 627, 994)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2786)
[M::mem_pestat] mean and std.dev: (590.10, 645.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3682)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 355, 989)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2529)
[M::mem_pestat] mean and std.dev: (502.17, 451.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3299)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 733648 reads in 191.362 CPU sec, 6.180 real sec
[M::mem_process_seqs] Processed 731046 reads in 122.831 CPU sec, 3.945 real sec
sorting block 133, #reads = 1094922 mem = 536883368 peak = 1096388608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 300882, 26, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 331, 1546)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4236)
[M::mem_pestat] mean and std.dev: (804.30, 967.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5581)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 182, 263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 531)
[M::mem_pestat] mean and std.dev: (203.80, 98.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 665)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 433, 495)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1195)
[M::mem_pestat] mean and std.dev: (305.64, 194.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1545)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (273, 404, 1286)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3312)
[M::mem_pestat] mean and std.dev: (668.19, 737.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4325)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 729322 sequences (100000253 bp) in 2.833 CPU sec, 2.917 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 300106, 36, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 305, 980)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2576)
[M::mem_pestat] mean and std.dev: (600.98, 631.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3374)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 182, 264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 534)
[M::mem_pestat] mean and std.dev: (204.34, 99.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 669)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (463, 572, 779)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1411)
[M::mem_pestat] mean and std.dev: (583.45, 293.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1756)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 308, 1184)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3230)
[M::mem_pestat] mean and std.dev: (697.18, 819.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4253)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727102 sequences (100000109 bp) in 2.030 CPU sec, 2.029 real sec...
[M::mem_process_seqs] Processed 730130 reads in 185.477 CPU sec, 5.920 real sec
[M::mem_process_seqs] Processed 729718 reads in 121.319 CPU sec, 3.900 real sec
sorting block 134, #reads = 1097969 mem = 536876938 peak = 1096388608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 300310, 23, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 338, 855)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2223)
[M::mem_pestat] mean and std.dev: (523.02, 473.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2907)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 183, 264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 534)
[M::mem_pestat] mean and std.dev: (204.56, 99.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 669)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 783, 1910)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5346)
[M::mem_pestat] mean and std.dev: (1245.00, 1365.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7064)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 497, 1311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3535)
[M::mem_pestat] mean and std.dev: (662.03, 660.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4647)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726056 sequences (100000252 bp) in 2.745 CPU sec, 2.785 real sec...
[M::process] read 725944 sequences (100000301 bp) in 1.940 CPU sec, 1.941 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 299517, 39, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 323, 1328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3572)
[M::mem_pestat] mean and std.dev: (631.20, 621.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4694)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 186, 270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 548)
[M::mem_pestat] mean and std.dev: (208.57, 101.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 687)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (339, 500, 1960)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5202)
[M::mem_pestat] mean and std.dev: (1007.86, 1107.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6823)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 240, 695)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1783)
[M::mem_pestat] mean and std.dev: (377.02, 339.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2327)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 729322 reads in 189.417 CPU sec, 6.070 real sec
sorting block 135, #reads = 1097202 mem = 536893089 peak = 1096388608
[M::mem_process_seqs] Processed 727102 reads in 120.716 CPU sec, 3.824 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 299147, 25, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 286, 1224)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3362)
[M::mem_pestat] mean and std.dev: (509.51, 483.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4431)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 188, 273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 555)
[M::mem_pestat] mean and std.dev: (210.71, 103.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 696)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (342, 383, 1203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2925)
[M::mem_pestat] mean and std.dev: (621.83, 568.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3786)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 598, 1167)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3149)
[M::mem_pestat] mean and std.dev: (710.48, 692.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4140)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 136, #reads = 1096785 mem = 536879930 peak = 1098006528
[M::process] read 725716 sequences (100000231 bp) in 2.351 CPU sec, 2.445 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 299168, 26, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 415, 838)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2114)
[M::mem_pestat] mean and std.dev: (519.42, 438.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2752)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 188, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 558)
[M::mem_pestat] mean and std.dev: (210.93, 103.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 700)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (278, 446, 924)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2216)
[M::mem_pestat] mean and std.dev: (418.43, 275.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2862)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 495, 1232)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3250)
[M::mem_pestat] mean and std.dev: (860.23, 846.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4259)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725886 sequences (100000057 bp) in 1.570 CPU sec, 1.563 real sec...
[M::mem_process_seqs] Processed 726056 reads in 153.848 CPU sec, 4.906 real sec
[M::mem_process_seqs] Processed 725944 reads in 99.138 CPU sec, 3.238 real sec
sorting block 137, #reads = 1097071 mem = 536887169 peak = 1098006528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 298894, 42, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 198, 998)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2648)
[M::mem_pestat] mean and std.dev: (451.66, 430.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3473)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 188, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 558)
[M::mem_pestat] mean and std.dev: (211.55, 104.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 700)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 590, 1043)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2857)
[M::mem_pestat] mean and std.dev: (588.65, 557.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3764)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 366, 510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1184)
[M::mem_pestat] mean and std.dev: (375.67, 251.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1521)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727128 sequences (100000224 bp) in 2.373 CPU sec, 2.469 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 299577, 39, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (315, 513, 1062)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2556)
[M::mem_pestat] mean and std.dev: (644.58, 494.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3303)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 188, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 558)
[M::mem_pestat] mean and std.dev: (211.04, 103.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 700)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (469, 944, 2286)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5920)
[M::mem_pestat] mean and std.dev: (1200.86, 1006.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7737)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 395, 1917)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5339)
[M::mem_pestat] mean and std.dev: (1110.43, 1300.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7050)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 729358 sequences (100000211 bp) in 1.610 CPU sec, 1.618 real sec...
[M::mem_process_seqs] Processed 725716 reads in 161.216 CPU sec, 5.234 real sec
[M::mem_process_seqs] Processed 725886 reads in 106.888 CPU sec, 3.490 real sec
sorting block 138, #reads = 1096236 mem = 536884002 peak = 1098006528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 298973, 28, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 385, 986)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2620)
[M::mem_pestat] mean and std.dev: (542.04, 572.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3437)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 185, 269)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 545)
[M::mem_pestat] mean and std.dev: (207.97, 101.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 683)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (305, 1001, 3555)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10055)
[M::mem_pestat] mean and std.dev: (2168.29, 2143.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13305)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 661, 1497)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4025)
[M::mem_pestat] mean and std.dev: (763.63, 751.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5289)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727484 sequences (100000006 bp) in 2.637 CPU sec, 2.678 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 299891, 43, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 244, 787)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2015)
[M::mem_pestat] mean and std.dev: (420.48, 426.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2629)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 182, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 525)
[M::mem_pestat] mean and std.dev: (202.86, 97.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 657)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 665, 1064)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2746)
[M::mem_pestat] mean and std.dev: (687.71, 601.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3587)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 472, 1236)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3298)
[M::mem_pestat] mean and std.dev: (683.92, 639.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4329)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726900 sequences (100000049 bp) in 1.970 CPU sec, 1.975 real sec...
[M::mem_process_seqs] Processed 727128 reads in 174.530 CPU sec, 5.632 real sec
sorting block 139, #reads = 1098085 mem = 536879043 peak = 1098006528
[M::mem_process_seqs] Processed 729358 reads in 112.557 CPU sec, 3.565 real sec
sorting block 140, #reads = 1095684 mem = 536884580 peak = 1098006528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 299257, 56, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 325, 696)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1670)
[M::mem_pestat] mean and std.dev: (417.00, 302.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2157)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 266)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 536)
[M::mem_pestat] mean and std.dev: (206.25, 99.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 671)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 460, 1282)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3388)
[M::mem_pestat] mean and std.dev: (704.42, 706.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4441)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 429, 820)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2082)
[M::mem_pestat] mean and std.dev: (477.94, 379.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2713)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726724 sequences (100000270 bp) in 2.716 CPU sec, 2.776 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 299445, 46, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (292, 695, 1682)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4462)
[M::mem_pestat] mean and std.dev: (997.37, 988.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5852)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 186, 269)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 545)
[M::mem_pestat] mean and std.dev: (207.86, 101.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 683)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (326, 561, 1356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3416)
[M::mem_pestat] mean and std.dev: (796.52, 735.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4446)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 580, 1999)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5531)
[M::mem_pestat] mean and std.dev: (1146.46, 1126.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7297)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726432 sequences (100000140 bp) in 1.990 CPU sec, 1.989 real sec...
[M::mem_process_seqs] Processed 727484 reads in 171.862 CPU sec, 5.581 real sec
[M::mem_process_seqs] Processed 726900 reads in 109.065 CPU sec, 3.575 real sec
sorting block 141, #reads = 1096204 mem = 536881972 peak = 1098006528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 298571, 28, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 528, 1160)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3014)
[M::mem_pestat] mean and std.dev: (676.36, 556.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3941)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 186, 269)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 545)
[M::mem_pestat] mean and std.dev: (208.00, 101.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 683)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 743, 1301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3611)
[M::mem_pestat] mean and std.dev: (685.42, 639.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4766)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 361, 1166)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3026)
[M::mem_pestat] mean and std.dev: (575.18, 476.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3956)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725092 sequences (100000032 bp) in 2.669 CPU sec, 2.740 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 299431, 36, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (266, 607, 1189)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3035)
[M::mem_pestat] mean and std.dev: (723.81, 567.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3958)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 186, 270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 548)
[M::mem_pestat] mean and std.dev: (208.74, 101.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 687)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (261, 534, 1666)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4476)
[M::mem_pestat] mean and std.dev: (900.00, 985.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5881)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 541, 1290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3486)
[M::mem_pestat] mean and std.dev: (744.51, 747.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4584)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724742 sequences (100000248 bp) in 1.970 CPU sec, 1.970 real sec...
[M::mem_process_seqs] Processed 726724 reads in 171.976 CPU sec, 5.589 real sec
[M::mem_process_seqs] Processed 726432 reads in 111.187 CPU sec, 3.593 real sec
sorting block 142, #reads = 1094965 mem = 536883190 peak = 1098006528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 298001, 44, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 451, 836)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1978)
[M::mem_pestat] mean and std.dev: (514.94, 357.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2549)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 188, 272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 552)
[M::mem_pestat] mean and std.dev: (210.18, 102.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 692)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 716, 1660)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4522)
[M::mem_pestat] mean and std.dev: (961.79, 850.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5953)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 405, 1144)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2954)
[M::mem_pestat] mean and std.dev: (703.95, 741.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3859)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724522 sequences (100000159 bp) in 2.656 CPU sec, 2.721 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 297543, 45, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (281, 602, 1721)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4601)
[M::mem_pestat] mean and std.dev: (1045.18, 1014.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6041)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 188, 271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 547)
[M::mem_pestat] mean and std.dev: (209.75, 101.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 685)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (324, 656, 1147)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2793)
[M::mem_pestat] mean and std.dev: (696.35, 631.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3616)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 381, 918)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2354)
[M::mem_pestat] mean and std.dev: (517.98, 457.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3072)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724644 sequences (100000209 bp) in 1.990 CPU sec, 1.988 real sec...
[M::mem_process_seqs] Processed 725092 reads in 169.355 CPU sec, 5.437 real sec
sorting block 143, #reads = 1094411 mem = 536877583 peak = 1098006528
[M::mem_process_seqs] Processed 724742 reads in 108.826 CPU sec, 3.470 real sec
sorting block 144, #reads = 1093002 mem = 536889222 peak = 1099657216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 297905, 35, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (259, 392, 1354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3544)
[M::mem_pestat] mean and std.dev: (669.78, 623.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4639)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 188, 272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 550)
[M::mem_pestat] mean and std.dev: (210.28, 101.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 689)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 517, 843)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2171)
[M::mem_pestat] mean and std.dev: (508.21, 389.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2835)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 432, 944)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2394)
[M::mem_pestat] mean and std.dev: (705.52, 665.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3367)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726162 sequences (100000292 bp) in 2.555 CPU sec, 2.647 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 297214, 52, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 465, 1137)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2983)
[M::mem_pestat] mean and std.dev: (638.44, 518.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3906)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 725246 sequences (100000147 bp) in 1.600 CPU sec, 1.598 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (133, 188, 272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 550)
[M::mem_pestat] mean and std.dev: (210.07, 101.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 689)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (302, 619, 1174)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2918)
[M::mem_pestat] mean and std.dev: (672.98, 503.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3790)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 370, 752)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1758)
[M::mem_pestat] mean and std.dev: (475.88, 322.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2261)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724522 reads in 165.666 CPU sec, 5.282 real sec
[M::mem_process_seqs] Processed 724644 reads in 104.493 CPU sec, 3.318 real sec
sorting block 145, #reads = 1092701 mem = 536879788 peak = 1099657216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 298363, 26, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 341, 900)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2398)
[M::mem_pestat] mean and std.dev: (463.62, 462.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3147)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 186, 268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 540)
[M::mem_pestat] mean and std.dev: (207.43, 99.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 676)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (369, 624, 1503)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3771)
[M::mem_pestat] mean and std.dev: (759.12, 571.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4905)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 444, 1219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3171)
[M::mem_pestat] mean and std.dev: (689.37, 643.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4147)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725456 sequences (100000154 bp) in 2.533 CPU sec, 2.602 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 297914, 37, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 357, 614)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1400)
[M::mem_pestat] mean and std.dev: (391.80, 277.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1793)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 187, 269)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 543)
[M::mem_pestat] mean and std.dev: (208.34, 100.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 680)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 662, 1731)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4871)
[M::mem_pestat] mean and std.dev: (880.40, 866.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6441)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 375, 679)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1585)
[M::mem_pestat] mean and std.dev: (399.00, 255.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2038)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724534 sequences (100000006 bp) in 1.620 CPU sec, 1.616 real sec...
[M::mem_process_seqs] Processed 726162 reads in 165.814 CPU sec, 5.346 real sec
[M::mem_process_seqs] Processed 725246 reads in 105.697 CPU sec, 3.425 real sec
sorting block 146, #reads = 1088862 mem = 536887030 peak = 1099657216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 297864, 46, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 329, 1313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3527)
[M::mem_pestat] mean and std.dev: (646.16, 661.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4634)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 186, 268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 540)
[M::mem_pestat] mean and std.dev: (207.83, 100.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 676)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (279, 587, 1295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3327)
[M::mem_pestat] mean and std.dev: (805.70, 754.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4343)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 311, 627)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1423)
[M::mem_pestat] mean and std.dev: (407.21, 311.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1821)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724564 sequences (100000061 bp) in 2.789 CPU sec, 2.855 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 297697, 34, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 457, 804)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1988)
[M::mem_pestat] mean and std.dev: (527.26, 433.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2580)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 188, 270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 544)
[M::mem_pestat] mean and std.dev: (209.19, 100.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 681)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (418, 754, 867)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1765)
[M::mem_pestat] mean and std.dev: (666.69, 427.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2379)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 483, 1215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3169)
[M::mem_pestat] mean and std.dev: (768.02, 685.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4146)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 725456 reads in 158.199 CPU sec, 5.089 real sec
sorting block 147, #reads = 1091073 mem = 536881383 peak = 1099657216
[M::process] read 725322 sequences (100000004 bp) in 2.145 CPU sec, 2.154 real sec...
[M::mem_process_seqs] Processed 724534 reads in 103.988 CPU sec, 3.506 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 297673, 44, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 427, 1247)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3379)
[M::mem_pestat] mean and std.dev: (712.85, 654.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4445)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 187, 268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 538)
[M::mem_pestat] mean and std.dev: (207.91, 99.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 673)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (109, 302, 1267)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3583)
[M::mem_pestat] mean and std.dev: (767.89, 850.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4741)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 416, 1216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3208)
[M::mem_pestat] mean and std.dev: (739.25, 737.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4204)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 148, #reads = 1091460 mem = 536881849 peak = 1099657216
[M::process] read 724734 sequences (100000190 bp) in 2.383 CPU sec, 2.507 real sec...
[M::process] read 725068 sequences (100000224 bp) in 1.620 CPU sec, 1.616 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 297490, 46, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 487, 1326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3580)
[M::mem_pestat] mean and std.dev: (759.85, 764.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4707)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 187, 268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 540)
[M::mem_pestat] mean and std.dev: (207.61, 99.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 676)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (130, 544, 1135)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3145)
[M::mem_pestat] mean and std.dev: (751.04, 788.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4150)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 503, 1495)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4099)
[M::mem_pestat] mean and std.dev: (754.08, 780.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5401)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724564 reads in 167.669 CPU sec, 5.565 real sec
[M::mem_process_seqs] Processed 725322 reads in 109.972 CPU sec, 3.506 real sec
sorting block 149, #reads = 1090410 mem = 536882684 peak = 1099657216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 297349, 38, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 369, 937)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2343)
[M::mem_pestat] mean and std.dev: (545.29, 504.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3046)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 187, 268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 540)
[M::mem_pestat] mean and std.dev: (208.04, 99.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 676)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 823, 1572)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4344)
[M::mem_pestat] mean and std.dev: (917.83, 946.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5730)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 447, 871)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2223)
[M::mem_pestat] mean and std.dev: (507.24, 451.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2899)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725774 sequences (100000164 bp) in 2.773 CPU sec, 2.851 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 297819, 44, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 303, 849)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2069)
[M::mem_pestat] mean and std.dev: (556.60, 530.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2679)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 186, 267)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 537)
[M::mem_pestat] mean and std.dev: (207.46, 99.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 672)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 446, 2269)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6389)
[M::mem_pestat] mean and std.dev: (1275.36, 1685.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8449)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (264, 549, 1631)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4365)
[M::mem_pestat] mean and std.dev: (821.39, 749.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5732)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724758 sequences (100000097 bp) in 1.640 CPU sec, 1.638 real sec...
[M::mem_process_seqs] Processed 724734 reads in 159.118 CPU sec, 5.066 real sec
[M::mem_process_seqs] Processed 725068 reads in 102.986 CPU sec, 3.295 real sec
sorting block 150, #reads = 1090874 mem = 536882148 peak = 1099657216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 297755, 44, 84)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 435, 838)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2076)
[M::mem_pestat] mean and std.dev: (490.25, 382.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2695)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 528)
[M::mem_pestat] mean and std.dev: (205.30, 97.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 660)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 582, 962)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2418)
[M::mem_pestat] mean and std.dev: (638.17, 544.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3146)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 352, 911)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2299)
[M::mem_pestat] mean and std.dev: (517.26, 416.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2993)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 733036 sequences (100000241 bp) in 2.430 CPU sec, 2.509 real sec...
[M::mem_process_seqs] Processed 725774 reads in 96.020 CPU sec, 3.143 real sec
sorting block 151, #reads = 1090521 mem = 536880009 peak = 1099657216
[M::process] read 736248 sequences (100000267 bp) in 2.284 CPU sec, 2.468 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 296246, 57, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 544, 2246)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6300)
[M::mem_pestat] mean and std.dev: (1138.41, 1190.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8327)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 187, 268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 540)
[M::mem_pestat] mean and std.dev: (208.07, 99.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 676)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 349, 1062)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2916)
[M::mem_pestat] mean and std.dev: (530.40, 604.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3843)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 390, 737)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1699)
[M::mem_pestat] mean and std.dev: (413.46, 296.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2180)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 732974 sequences (100000021 bp) in 1.528 CPU sec, 1.525 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 301902, 43, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 338, 555)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1295)
[M::mem_pestat] mean and std.dev: (370.83, 295.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1665)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (125, 175, 249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 497)
[M::mem_pestat] mean and std.dev: (193.80, 91.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 621)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 541, 1133)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3041)
[M::mem_pestat] mean and std.dev: (676.56, 591.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3995)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 455, 1352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3676)
[M::mem_pestat] mean and std.dev: (770.03, 723.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4838)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724758 reads in 192.302 CPU sec, 6.149 real sec
sorting block 152, #reads = 1085132 mem = 536880344 peak = 1099657216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 300171, 33, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 339, 937)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2479)
[M::mem_pestat] mean and std.dev: (481.16, 444.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3250)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 178, 253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 505)
[M::mem_pestat] mean and std.dev: (197.30, 93.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 631)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (291, 489, 1317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3369)
[M::mem_pestat] mean and std.dev: (742.71, 703.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4395)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 380, 1942)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5348)
[M::mem_pestat] mean and std.dev: (991.27, 1314.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7051)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 731132 sequences (100000082 bp) in 1.845 CPU sec, 1.847 real sec...
[M::mem_process_seqs] Processed 736248 reads in 184.259 CPU sec, 5.845 real sec
[M::mem_process_seqs] Processed 733036 reads in 204.787 CPU sec, 6.833 real sec
sorting block 153, #reads = 1087857 mem = 536883659 peak = 1099657216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 300901, 36, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 300, 756)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1836)
[M::mem_pestat] mean and std.dev: (487.62, 436.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2376)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 178, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 514)
[M::mem_pestat] mean and std.dev: (198.92, 95.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 643)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (100, 628, 1024)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2872)
[M::mem_pestat] mean and std.dev: (562.13, 577.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3796)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 621, 1473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3979)
[M::mem_pestat] mean and std.dev: (635.43, 547.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5232)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 730348 sequences (100000155 bp) in 2.475 CPU sec, 2.608 real sec...
[M::process] read 727916 sequences (100000178 bp) in 1.510 CPU sec, 1.512 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 300346, 33, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 432, 1075)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2821)
[M::mem_pestat] mean and std.dev: (637.42, 557.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3694)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 180, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 524)
[M::mem_pestat] mean and std.dev: (201.73, 97.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 656)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (367, 570, 1029)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2353)
[M::mem_pestat] mean and std.dev: (570.97, 423.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3015)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 293, 928)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2388)
[M::mem_pestat] mean and std.dev: (469.22, 476.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3118)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 732974 reads in 162.070 CPU sec, 5.467 real sec
[M::mem_process_seqs] Processed 731132 reads in 102.271 CPU sec, 3.257 real sec
sorting block 154, #reads = 1089274 mem = 536882356 peak = 1099657216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 300153, 46, 87)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 505, 2411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6809)
[M::mem_pestat] mean and std.dev: (1251.27, 1626.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9008)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 182, 262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 528)
[M::mem_pestat] mean and std.dev: (203.07, 98.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 661)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 706, 1123)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2957)
[M::mem_pestat] mean and std.dev: (614.41, 460.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3874)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 274, 661)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1579)
[M::mem_pestat] mean and std.dev: (426.68, 349.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2038)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728674 sequences (100000196 bp) in 2.355 CPU sec, 2.494 real sec...
[M::process] read 726090 sequences (100000023 bp) in 1.560 CPU sec, 1.563 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 299213, 46, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 437, 782)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1968)
[M::mem_pestat] mean and std.dev: (551.75, 427.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2561)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 185, 269)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 545)
[M::mem_pestat] mean and std.dev: (207.80, 101.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 683)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 430, 1091)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2937)
[M::mem_pestat] mean and std.dev: (626.49, 612.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3860)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 291, 594)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1384)
[M::mem_pestat] mean and std.dev: (323.59, 192.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1779)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 730348 reads in 159.067 CPU sec, 5.166 real sec
sorting block 155, #reads = 1094606 mem = 536879791 peak = 1099657216
[M::mem_process_seqs] Processed 727916 reads in 101.061 CPU sec, 3.209 real sec
sorting block 156, #reads = 1094208 mem = 536880665 peak = 1107591168
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 299436, 31, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 386, 885)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2323)
[M::mem_pestat] mean and std.dev: (615.42, 579.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3042)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 184, 266)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 538)
[M::mem_pestat] mean and std.dev: (205.94, 100.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 674)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 564, 1082)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2770)
[M::mem_pestat] mean and std.dev: (586.52, 510.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3614)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 328, 953)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2413)
[M::mem_pestat] mean and std.dev: (548.49, 520.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3143)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726658 sequences (100000227 bp) in 2.311 CPU sec, 2.422 real sec...
[M::process] read 725296 sequences (100000161 bp) in 1.510 CPU sec, 1.512 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 298925, 38, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 273, 705)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1747)
[M::mem_pestat] mean and std.dev: (413.04, 344.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2268)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 187, 271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 549)
[M::mem_pestat] mean and std.dev: (209.82, 102.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 688)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 626, 1303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3457)
[M::mem_pestat] mean and std.dev: (765.14, 763.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4534)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 353, 686)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1632)
[M::mem_pestat] mean and std.dev: (450.95, 395.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2105)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 728674 reads in 157.752 CPU sec, 5.131 real sec
[M::mem_process_seqs] Processed 726090 reads in 101.274 CPU sec, 3.228 real sec
sorting block 157, #reads = 1093001 mem = 536879254 peak = 1107591168
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 298846, 27, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 205, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1068)
[M::mem_pestat] mean and std.dev: (283.67, 197.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1376)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 187, 272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 552)
[M::mem_pestat] mean and std.dev: (210.26, 103.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 692)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 983, 2983)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8471)
[M::mem_pestat] mean and std.dev: (2131.52, 2698.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12926)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 385, 2485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7129)
[M::mem_pestat] mean and std.dev: (1391.64, 1767.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9451)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726582 sequences (100000229 bp) in 2.295 CPU sec, 2.424 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 298018, 59, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (302, 464, 816)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1844)
[M::mem_pestat] mean and std.dev: (529.04, 357.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2358)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 189, 275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 559)
[M::mem_pestat] mean and std.dev: (211.82, 104.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 701)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (113, 461, 843)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2303)
[M::mem_pestat] mean and std.dev: (547.15, 538.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3033)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 324, 575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1345)
[M::mem_pestat] mean and std.dev: (393.77, 258.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1730)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726722 sequences (100000118 bp) in 1.480 CPU sec, 1.485 real sec...
[M::mem_process_seqs] Processed 726658 reads in 149.512 CPU sec, 4.774 real sec
[M::mem_process_seqs] Processed 725296 reads in 99.110 CPU sec, 3.169 real sec
sorting block 158, #reads = 1093108 mem = 536879720 peak = 1107591168
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 298518, 41, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 439, 1635)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4433)
[M::mem_pestat] mean and std.dev: (719.86, 849.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5832)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 186, 269)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 545)
[M::mem_pestat] mean and std.dev: (208.19, 101.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 683)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (456, 783, 1500)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3588)
[M::mem_pestat] mean and std.dev: (817.36, 628.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4632)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 319, 1028)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2580)
[M::mem_pestat] mean and std.dev: (558.06, 542.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3356)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 159, #reads = 1093387 mem = 536881721 peak = 1107591168
[M::process] read 725206 sequences (100000168 bp) in 2.296 CPU sec, 2.411 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 298864, 35, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (263, 418, 943)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2303)
[M::mem_pestat] mean and std.dev: (626.45, 502.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2983)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 186, 268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 542)
[M::mem_pestat] mean and std.dev: (207.64, 100.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 679)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 549, 1296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3392)
[M::mem_pestat] mean and std.dev: (668.67, 606.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4440)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 333, 999)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2569)
[M::mem_pestat] mean and std.dev: (515.88, 422.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3354)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724802 sequences (100000080 bp) in 1.500 CPU sec, 1.501 real sec...
[M::mem_process_seqs] Processed 726582 reads in 149.878 CPU sec, 4.778 real sec
[M::mem_process_seqs] Processed 726722 reads in 98.944 CPU sec, 3.165 real sec
sorting block 160, #reads = 1093354 mem = 536879219 peak = 1107591168
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 298186, 43, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 375, 1402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3794)
[M::mem_pestat] mean and std.dev: (706.30, 717.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4990)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 187, 271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 549)
[M::mem_pestat] mean and std.dev: (209.71, 101.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 688)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (377, 800, 1375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3371)
[M::mem_pestat] mean and std.dev: (998.05, 819.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4369)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 276, 558)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1222)
[M::mem_pestat] mean and std.dev: (326.14, 244.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1554)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723242 sequences (100000030 bp) in 2.250 CPU sec, 2.347 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 297669, 38, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 394, 814)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2080)
[M::mem_pestat] mean and std.dev: (505.36, 472.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2713)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 188, 273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 553)
[M::mem_pestat] mean and std.dev: (210.60, 102.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 693)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (307, 539, 1353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3445)
[M::mem_pestat] mean and std.dev: (899.42, 875.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4491)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 515, 989)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2583)
[M::mem_pestat] mean and std.dev: (571.32, 456.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3380)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723562 sequences (100000258 bp) in 1.480 CPU sec, 1.484 real sec...
[M::mem_process_seqs] Processed 725206 reads in 154.771 CPU sec, 4.960 real sec
[M::mem_process_seqs] Processed 724802 reads in 99.714 CPU sec, 3.161 real sec
sorting block 161, #reads = 1093027 mem = 536880062 peak = 1107591168
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 296738, 47, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (304, 745, 1854)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4954)
[M::mem_pestat] mean and std.dev: (1099.95, 1112.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6504)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 190, 275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 557)
[M::mem_pestat] mean and std.dev: (212.42, 102.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 698)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 373, 1412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3810)
[M::mem_pestat] mean and std.dev: (913.22, 1060.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5156)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 580, 1270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3298)
[M::mem_pestat] mean and std.dev: (723.03, 664.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4312)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723472 sequences (100000115 bp) in 2.246 CPU sec, 2.348 real sec...
[M::process] read 722350 sequences (100000115 bp) in 1.500 CPU sec, 1.491 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (89, 297351, 51, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 333, 915)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2331)
[M::mem_pestat] mean and std.dev: (538.51, 535.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3039)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 190, 275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 557)
[M::mem_pestat] mean and std.dev: (212.51, 102.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 698)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (311, 430, 1037)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2489)
[M::mem_pestat] mean and std.dev: (585.55, 462.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3215)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 271, 588)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1400)
[M::mem_pestat] mean and std.dev: (357.16, 257.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1806)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723242 reads in 152.094 CPU sec, 4.847 real sec
[M::mem_process_seqs] Processed 723562 reads in 101.197 CPU sec, 3.266 real sec
sorting block 162, #reads = 1092126 mem = 536879192 peak = 1107591168
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 297009, 38, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 391, 703)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1735)
[M::mem_pestat] mean and std.dev: (503.85, 395.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2251)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 190, 275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 557)
[M::mem_pestat] mean and std.dev: (212.27, 102.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 698)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 630, 1333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3635)
[M::mem_pestat] mean and std.dev: (773.43, 706.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4786)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 557, 911)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2281)
[M::mem_pestat] mean and std.dev: (610.48, 534.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2966)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 163, #reads = 1089632 mem = 536876928 peak = 1107591168
[M::process] read 722490 sequences (100000290 bp) in 2.325 CPU sec, 2.433 real sec...
[M::process] read 722176 sequences (100000172 bp) in 1.500 CPU sec, 1.499 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 296176, 40, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 332, 1118)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3008)
[M::mem_pestat] mean and std.dev: (504.53, 528.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3953)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 192, 276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 558)
[M::mem_pestat] mean and std.dev: (213.24, 102.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 699)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 510, 990)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2564)
[M::mem_pestat] mean and std.dev: (569.63, 408.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3351)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 319, 819)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1965)
[M::mem_pestat] mean and std.dev: (461.98, 380.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2538)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723472 reads in 158.747 CPU sec, 5.107 real sec
[M::mem_process_seqs] Processed 722350 reads in 101.435 CPU sec, 3.348 real sec
sorting block 164, #reads = 1089329 mem = 536880293 peak = 1107591168
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 296368, 32, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 439, 1096)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2880)
[M::mem_pestat] mean and std.dev: (627.10, 528.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3772)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 192, 276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 558)
[M::mem_pestat] mean and std.dev: (213.08, 102.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 699)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (484, 619, 2324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6004)
[M::mem_pestat] mean and std.dev: (1189.33, 1309.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7844)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 379, 1177)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3033)
[M::mem_pestat] mean and std.dev: (642.02, 597.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3961)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721962 sequences (100000045 bp) in 2.277 CPU sec, 2.386 real sec...
[M::process] read 721482 sequences (100000148 bp) in 1.490 CPU sec, 1.493 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 296075, 41, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (389, 847, 1625)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4097)
[M::mem_pestat] mean and std.dev: (926.04, 728.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5333)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 191, 275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 555)
[M::mem_pestat] mean and std.dev: (212.60, 101.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 695)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (712, 1014, 1772)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3892)
[M::mem_pestat] mean and std.dev: (1129.87, 622.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4952)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 511, 842)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2122)
[M::mem_pestat] mean and std.dev: (492.50, 396.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2762)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 722490 reads in 155.298 CPU sec, 5.069 real sec
[M::mem_process_seqs] Processed 722176 reads in 99.735 CPU sec, 3.183 real sec
sorting block 165, #reads = 1088762 mem = 536881698 peak = 1107591168
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 296339, 41, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 398, 1369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3669)
[M::mem_pestat] mean and std.dev: (802.26, 747.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4819)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 191, 275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 555)
[M::mem_pestat] mean and std.dev: (212.41, 101.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 695)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 717, 1802)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5116)
[M::mem_pestat] mean and std.dev: (1007.55, 1099.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6773)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 646, 1810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4942)
[M::mem_pestat] mean and std.dev: (841.83, 997.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6508)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721544 sequences (100000232 bp) in 2.330 CPU sec, 2.438 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 296253, 38, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 466, 1139)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3043)
[M::mem_pestat] mean and std.dev: (693.75, 632.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3995)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 192, 276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 558)
[M::mem_pestat] mean and std.dev: (213.27, 101.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 699)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 487, 785)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1885)
[M::mem_pestat] mean and std.dev: (480.97, 326.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2435)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 397, 787)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1893)
[M::mem_pestat] mean and std.dev: (451.88, 352.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2446)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721656 sequences (100000115 bp) in 1.500 CPU sec, 1.495 real sec...
[M::mem_process_seqs] Processed 721962 reads in 151.901 CPU sec, 4.847 real sec
[M::mem_process_seqs] Processed 721482 reads in 97.245 CPU sec, 3.166 real sec
sorting block 166, #reads = 1089716 mem = 536884865 peak = 1107591168
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 296047, 56, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 367, 1109)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2901)
[M::mem_pestat] mean and std.dev: (595.06, 570.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3797)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 192, 275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 555)
[M::mem_pestat] mean and std.dev: (212.90, 101.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 695)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (569, 968, 1913)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4601)
[M::mem_pestat] mean and std.dev: (1286.73, 1129.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5945)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 433, 788)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1978)
[M::mem_pestat] mean and std.dev: (530.85, 430.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2573)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 167, #reads = 1090742 mem = 536881313 peak = 1107591168
[M::process] read 721768 sequences (100000033 bp) in 2.328 CPU sec, 2.438 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 296445, 40, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 375, 836)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2130)
[M::mem_pestat] mean and std.dev: (480.44, 444.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2777)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 191, 273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 549)
[M::mem_pestat] mean and std.dev: (211.72, 100.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 687)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (533, 873, 1903)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4643)
[M::mem_pestat] mean and std.dev: (919.40, 775.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6013)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 339, 841)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2047)
[M::mem_pestat] mean and std.dev: (446.77, 364.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2650)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721046 sequences (100000101 bp) in 1.480 CPU sec, 1.486 real sec...
[M::mem_process_seqs] Processed 721544 reads in 151.958 CPU sec, 4.928 real sec
[M::mem_process_seqs] Processed 721656 reads in 100.018 CPU sec, 3.193 real sec
sorting block 168, #reads = 1090907 mem = 536881557 peak = 1107591168
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 296369, 32, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (288, 605, 1167)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2925)
[M::mem_pestat] mean and std.dev: (630.76, 530.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3804)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 191, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 552)
[M::mem_pestat] mean and std.dev: (212.08, 100.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 691)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 266, 689)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1659)
[M::mem_pestat] mean and std.dev: (365.46, 360.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2144)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 434, 1049)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2749)
[M::mem_pestat] mean and std.dev: (700.53, 698.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3599)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721408 sequences (100000240 bp) in 2.268 CPU sec, 2.367 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 296099, 60, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 266, 566)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1348)
[M::mem_pestat] mean and std.dev: (289.39, 199.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1739)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 193, 276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 556)
[M::mem_pestat] mean and std.dev: (213.21, 101.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 696)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 615, 1442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4016)
[M::mem_pestat] mean and std.dev: (800.40, 913.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5303)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 325, 778)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1950)
[M::mem_pestat] mean and std.dev: (469.32, 418.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2536)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721042 sequences (100000065 bp) in 1.510 CPU sec, 1.508 real sec...
[M::mem_process_seqs] Processed 721768 reads in 146.802 CPU sec, 4.671 real sec
[M::mem_process_seqs] Processed 721046 reads in 96.572 CPU sec, 3.062 real sec
sorting block 169, #reads = 1091528 mem = 536881413 peak = 1107591168
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 296427, 41, 84)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 552, 1656)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4472)
[M::mem_pestat] mean and std.dev: (1028.53, 1156.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5880)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 193, 276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 558)
[M::mem_pestat] mean and std.dev: (213.38, 101.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 699)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (108, 426, 686)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1842)
[M::mem_pestat] mean and std.dev: (398.10, 342.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2420)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 380, 1173)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3083)
[M::mem_pestat] mean and std.dev: (677.54, 684.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4038)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721420 sequences (100000065 bp) in 2.320 CPU sec, 2.432 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 296489, 48, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 281, 1189)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3207)
[M::mem_pestat] mean and std.dev: (559.98, 535.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4216)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 193, 277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 559)
[M::mem_pestat] mean and std.dev: (213.91, 101.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 700)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 623, 1299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3481)
[M::mem_pestat] mean and std.dev: (780.76, 636.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4572)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 405, 1353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3657)
[M::mem_pestat] mean and std.dev: (713.74, 711.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4809)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720932 sequences (100000055 bp) in 1.500 CPU sec, 1.498 real sec...
[M::mem_process_seqs] Processed 721408 reads in 146.137 CPU sec, 4.658 real sec
[M::mem_process_seqs] Processed 721042 reads in 96.031 CPU sec, 3.078 real sec
sorting block 170, #reads = 1089415 mem = 536880147 peak = 1107591168
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 296170, 28, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 462, 681)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1575)
[M::mem_pestat] mean and std.dev: (379.50, 202.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2022)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 192, 275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 555)
[M::mem_pestat] mean and std.dev: (212.92, 101.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 695)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 665, 1172)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3068)
[M::mem_pestat] mean and std.dev: (687.08, 582.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4016)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 286, 892)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2288)
[M::mem_pestat] mean and std.dev: (496.48, 503.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2986)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 171, #reads = 1091846 mem = 536884715 peak = 1107591168
[M::process] read 720804 sequences (100000172 bp) in 2.259 CPU sec, 2.354 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 296527, 46, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 375, 767)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1911)
[M::mem_pestat] mean and std.dev: (474.51, 397.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2483)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 192, 276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 558)
[M::mem_pestat] mean and std.dev: (213.53, 102.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 699)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 406, 1521)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4225)
[M::mem_pestat] mean and std.dev: (710.02, 853.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5577)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (282, 409, 2201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6039)
[M::mem_pestat] mean and std.dev: (757.84, 841.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7958)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 632480 sequences (87530095 bp) in 1.390 CPU sec, 1.394 real sec...
[M::mem_process_seqs] Processed 721420 reads in 150.236 CPU sec, 4.815 real sec
[M::mem_process_seqs] Processed 720932 reads in 97.098 CPU sec, 3.091 real sec
sorting block 172, #reads = 1090785 mem = 536881319 peak = 1107591168
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 295842, 46, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 414, 1238)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3238)
[M::mem_pestat] mean and std.dev: (758.81, 649.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4238)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 193, 277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 559)
[M::mem_pestat] mean and std.dev: (214.12, 102.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 700)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (123, 444, 1476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4182)
[M::mem_pestat] mean and std.dev: (803.30, 999.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5535)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (299, 578, 1177)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2933)
[M::mem_pestat] mean and std.dev: (656.28, 512.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3811)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 720804 reads in 80.916 CPU sec, 2.682 real sec
sorting block 173, #reads = 1090382 mem = 536878269 peak = 1107591168
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 259648, 26, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 384, 1122)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3036)
[M::mem_pestat] mean and std.dev: (621.30, 696.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3993)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 191, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 554)
[M::mem_pestat] mean and std.dev: (211.83, 101.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 694)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 368, 615)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1355)
[M::mem_pestat] mean and std.dev: (373.04, 246.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1725)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 267, 771)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1929)
[M::mem_pestat] mean and std.dev: (377.21, 291.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2508)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 632480 reads in 90.426 CPU sec, 3.029 real sec
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 189109406
overall: 70438457344 mem 28136.852 user 534.125 sys 948.105 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1136_4Z5-T1-TDNA-1_A23MHWWLT4_1.L001\tPU:L001\tSM:1136_4Z5-T1-TDNA-1_A23MHWWLT4_1\tLB:1136_4Z5-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1136_4Z5-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1136_4Z5-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 948.144 sec; CPU: 28670.979 sec
sorting block 174, #reads = 694480 mem = 342592335 peak = 1107591168
uniq header count 1
merging 175 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31 max 192
algo: util-sort
license: sentieon:util=1
output file size: 9823541655
output reads: 190840299
bam_mem_sort: 175 calls 105.469 user 2.379 sys 108.384 real
bam_write: 175 calls 57.441 user 3.789 sys 69.652 real
execute: 1 calls 36.506 user 1.331 sys 997.429 real
merge_files: 1 calls 36.482 user 1.310 sys 48.645 real
parse_chunk: 2795 calls 116.683 user 31.664 sys 154.104 real
read_chunk: 7578 calls 61.743 user 51.224 sys 887.437 real
sort_block: 1 calls 43.173 user 50.498 sys 861.763 real
write_chunk: 4781 calls 36.121 user 0.923 sys 47.624 real
overall: 3939545088 mem 2052.052 user 112.002 sys 997.453 real
ls: cannot access '*.cram': No such file or directory