This software is licensed to bgold@natera.com by Sentieon Inc. cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1136_81F-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam - This software is licensed to bgold@natera.com by Sentieon Inc. version: sentieon-genomics-202308.03 [M::bwa_idx_load_from_disk] read 3171 ALT contigs [M::main_mem] bwa index loaded in 1461.725 CPU sec, 53.145 real sec [M::process] read 776752 sequences (100000139 bp) in 1.247 CPU sec, 1.248 real sec... [M::process] read 775464 sequences (100000020 bp) in 1.860 CPU sec, 1.866 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 295663, 33, 62) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (174, 229, 938) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2466) [M::mem_pestat] mean and std.dev: (452.80, 478.47) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3230) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (108, 144, 194) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 366) [M::mem_pestat] mean and std.dev: (155.29, 62.71) [M::mem_pestat] low and high boundaries for proper pairs: (1, 452) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (218, 572, 1479) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4001) [M::mem_pestat] mean and std.dev: (787.43, 847.73) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5262) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (196, 490, 1036) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2716) [M::mem_pestat] mean and std.dev: (620.29, 529.82) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3556) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 774358 sequences (100000123 bp) in 1.913 CPU sec, 1.921 real sec... [M::process] read 774808 sequences (100000143 bp) in 1.924 CPU sec, 1.960 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 295671, 39, 59) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (150, 282, 1017) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2751) [M::mem_pestat] mean and std.dev: (541.05, 594.09) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3618) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (109, 144, 195) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 367) [M::mem_pestat] mean and std.dev: (156.22, 63.30) [M::mem_pestat] low and high boundaries for proper pairs: (1, 453) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (105, 484, 1407) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4011) [M::mem_pestat] mean and std.dev: (658.82, 809.47) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5313) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (179, 254, 562) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1328) [M::mem_pestat] mean and std.dev: (317.32, 250.92) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1711) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 776752 reads in 267.344 CPU sec, 8.512 real sec [M::mem_process_seqs] Processed 775464 reads in 196.366 CPU sec, 6.352 real sec sorting block 0, #reads = 1084838 mem = 536887986 peak = 580919296 [M::process] read 774048 sequences (100000072 bp) in 2.276 CPU sec, 2.330 real sec... [M::process] read 774240 sequences (100000198 bp) in 1.826 CPU sec, 1.834 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 296797, 35, 51) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (154, 203, 672) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1708) [M::mem_pestat] mean and std.dev: (335.00, 332.44) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2226) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (109, 145, 196) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 370) [M::mem_pestat] mean and std.dev: (157.06, 64.13) [M::mem_pestat] low and high boundaries for proper pairs: (1, 457) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (166, 727, 1150) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3118) [M::mem_pestat] mean and std.dev: (785.18, 753.66) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4102) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (219, 355, 783) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1911) [M::mem_pestat] mean and std.dev: (434.17, 325.82) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2475) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 296430, 29, 66) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (171, 381, 1193) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3237) [M::mem_pestat] mean and std.dev: (600.91, 655.35) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4259) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (109, 145, 196) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 370) [M::mem_pestat] mean and std.dev: (157.07, 63.94) [M::mem_pestat] low and high boundaries for proper pairs: (1, 457) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (156, 600, 1428) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3972) [M::mem_pestat] mean and std.dev: (889.28, 896.27) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5244) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (244, 493, 960) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2392) [M::mem_pestat] mean and std.dev: (542.74, 461.23) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3108) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 774808 reads in 271.620 CPU sec, 8.687 real sec sorting block 1, #reads = 1084460 mem = 536889121 peak = 807358464 [M::mem_process_seqs] Processed 774358 reads in 315.273 CPU sec, 10.141 real sec [M::process] read 773088 sequences (100000164 bp) in 2.729 CPU sec, 2.770 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 296648, 53, 69) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (159, 295, 985) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2637) [M::mem_pestat] mean and std.dev: (358.07, 296.04) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3463) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (109, 145, 197) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 373) [M::mem_pestat] mean and std.dev: (157.62, 64.65) [M::mem_pestat] low and high boundaries for proper pairs: (1, 461) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (279, 736, 2359) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6519) [M::mem_pestat] mean and std.dev: (1125.19, 1111.30) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8599) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (155, 288, 748) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1934) [M::mem_pestat] mean and std.dev: (376.74, 323.13) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2527) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 772434 sequences (100000161 bp) in 2.068 CPU sec, 2.101 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 296599, 37, 71) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (124, 253, 603) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1561) [M::mem_pestat] mean and std.dev: (360.74, 381.09) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2040) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (109, 145, 196) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 370) [M::mem_pestat] mean and std.dev: (157.07, 64.13) [M::mem_pestat] low and high boundaries for proper pairs: (1, 457) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (431, 748, 1499) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3635) [M::mem_pestat] mean and std.dev: (872.00, 699.27) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4703) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (161, 286, 732) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1874) [M::mem_pestat] mean and std.dev: (392.69, 326.40) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2445) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 774048 reads in 271.972 CPU sec, 8.687 real sec sorting block 2, #reads = 1085345 mem = 536879956 peak = 890105856 [M::process] read 771740 sequences (100000225 bp) in 2.579 CPU sec, 2.746 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 296103, 29, 75) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (153, 307, 1716) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4842) [M::mem_pestat] mean and std.dev: (653.36, 956.61) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6405) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 146, 198) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374) [M::mem_pestat] mean and std.dev: (158.34, 64.94) [M::mem_pestat] low and high boundaries for proper pairs: (1, 462) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (225, 440, 2238) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6264) [M::mem_pestat] mean and std.dev: (1195.25, 1317.53) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8277) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (259, 358, 1141) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2905) [M::mem_pestat] mean and std.dev: (569.28, 515.91) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3787) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 772434 reads in 158.402 CPU sec, 5.046 real sec sorting block 3, #reads = 1087106 mem = 536883877 peak = 890105856 [M::mem_process_seqs] Processed 774240 reads in 508.451 CPU sec, 16.291 real sec sorting block 4, #reads = 1085805 mem = 536880256 peak = 890105856 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 296228, 27, 52) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (222, 428, 917) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2307) [M::mem_pestat] mean and std.dev: (376.58, 233.88) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3002) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (109, 146, 197) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 373) [M::mem_pestat] mean and std.dev: (157.85, 64.58) [M::mem_pestat] low and high boundaries for proper pairs: (1, 461) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (171, 434, 944) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2490) [M::mem_pestat] mean and std.dev: (471.24, 412.80) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3263) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (167, 313, 908) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2390) [M::mem_pestat] mean and std.dev: (496.37, 454.30) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3131) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 771394 sequences (100000076 bp) in 2.859 CPU sec, 2.903 real sec... [M::process] read 771590 sequences (100000136 bp) in 2.050 CPU sec, 2.063 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 295828, 31, 57) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (151, 292, 1048) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2842) [M::mem_pestat] mean and std.dev: (556.79, 562.44) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3739) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377) [M::mem_pestat] mean and std.dev: (158.94, 65.43) [M::mem_pestat] low and high boundaries for proper pairs: (1, 466) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (200, 428, 1058) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2774) [M::mem_pestat] mean and std.dev: (566.39, 545.31) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3632) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (170, 276, 1505) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4175) [M::mem_pestat] mean and std.dev: (677.19, 851.12) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5510) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 773088 reads in 436.122 CPU sec, 13.917 real sec [M::mem_process_seqs] Processed 771740 reads in 203.178 CPU sec, 6.524 real sec sorting block 5, #reads = 1086444 mem = 536883762 peak = 890105856 [M::process] read 771886 sequences (100000015 bp) in 2.634 CPU sec, 2.707 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 295696, 37, 57) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (190, 389, 1185) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3175) [M::mem_pestat] mean and std.dev: (581.46, 522.59) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4170) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377) [M::mem_pestat] mean and std.dev: (158.89, 65.27) [M::mem_pestat] low and high boundaries for proper pairs: (1, 466) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (173, 417, 1808) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5078) [M::mem_pestat] mean and std.dev: (1016.35, 1266.18) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6713) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (171, 328, 830) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2148) [M::mem_pestat] mean and std.dev: (459.47, 491.16) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2807) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 771092 sequences (100000175 bp) in 2.015 CPU sec, 2.017 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 295507, 35, 74) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (157, 396, 993) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2665) [M::mem_pestat] mean and std.dev: (558.18, 551.65) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3501) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377) [M::mem_pestat] mean and std.dev: (159.03, 65.54) [M::mem_pestat] low and high boundaries for proper pairs: (1, 466) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (232, 379, 2174) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6058) [M::mem_pestat] mean and std.dev: (1144.12, 1308.57) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8000) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (188, 335, 1009) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2651) [M::mem_pestat] mean and std.dev: (514.85, 497.99) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3472) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 295498, 32, 73) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (154, 439, 2158) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6166) [M::mem_pestat] mean and std.dev: (957.92, 1104.50) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8170) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 146, 199) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377) [M::mem_pestat] mean and std.dev: (158.76, 65.37) [M::mem_pestat] low and high boundaries for proper pairs: (1, 466) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (200, 767, 1273) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3419) [M::mem_pestat] mean and std.dev: (556.04, 431.78) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4492) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (178, 299, 1179) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3181) [M::mem_pestat] mean and std.dev: (405.33, 387.36) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4182) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 771394 reads in 392.759 CPU sec, 12.651 real sec sorting block 6, #reads = 1086888 mem = 536884300 peak = 890105856 [M::mem_process_seqs] Processed 771590 reads in 312.458 CPU sec, 10.143 real sec [M::mem_process_seqs] Processed 771886 reads in 356.212 CPU sec, 11.546 real sec sorting block 7, #reads = 1087112 mem = 536879682 peak = 890105856 [M::process] read 770318 sequences (100000051 bp) in 3.141 CPU sec, 3.202 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 295294, 44, 77) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (155, 328, 995) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2675) [M::mem_pestat] mean and std.dev: (535.14, 499.51) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3515) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377) [M::mem_pestat] mean and std.dev: (159.02, 65.41) [M::mem_pestat] low and high boundaries for proper pairs: (1, 466) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (253, 638, 1966) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5392) [M::mem_pestat] mean and std.dev: (1060.93, 1218.14) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7105) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (205, 407, 888) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2254) [M::mem_pestat] mean and std.dev: (545.63, 486.97) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2937) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 769502 sequences (100000029 bp) in 2.744 CPU sec, 2.827 real sec... [M::process] read 768300 sequences (100000172 bp) in 2.190 CPU sec, 2.193 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 295099, 49, 62) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (151, 232, 834) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2200) [M::mem_pestat] mean and std.dev: (450.72, 465.22) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2883) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380) [M::mem_pestat] mean and std.dev: (159.83, 66.15) [M::mem_pestat] low and high boundaries for proper pairs: (1, 470) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (175, 535, 1454) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4012) [M::mem_pestat] mean and std.dev: (696.65, 604.32) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5291) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (212, 458, 1123) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2945) [M::mem_pestat] mean and std.dev: (700.27, 700.49) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3856) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 771092 reads in 263.748 CPU sec, 8.399 real sec sorting block 8, #reads = 1085328 mem = 536880901 peak = 890105856 [M::mem_process_seqs] Processed 770318 reads in 186.493 CPU sec, 5.938 real sec sorting block 9, #reads = 1085600 mem = 536880914 peak = 890105856 [M::process] read 768120 sequences (100000129 bp) in 2.251 CPU sec, 2.323 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 294682, 36, 56) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (174, 242, 599) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1449) [M::mem_pestat] mean and std.dev: (373.47, 295.46) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1874) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (111, 149, 202) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384) [M::mem_pestat] mean and std.dev: (161.24, 66.80) [M::mem_pestat] low and high boundaries for proper pairs: (1, 475) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (192, 429, 682) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1662) [M::mem_pestat] mean and std.dev: (378.97, 336.18) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2152) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (154, 276, 877) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2323) [M::mem_pestat] mean and std.dev: (517.15, 528.56) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3046) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 768804 sequences (100000122 bp) in 1.800 CPU sec, 1.796 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 294539, 34, 71) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (128, 196, 610) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1574) [M::mem_pestat] mean and std.dev: (305.51, 273.21) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2056) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 148, 201) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 383) [M::mem_pestat] mean and std.dev: (160.63, 66.79) [M::mem_pestat] low and high boundaries for proper pairs: (1, 474) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (202, 693, 1477) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4027) [M::mem_pestat] mean and std.dev: (716.97, 761.20) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5302) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (178, 300, 702) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1750) [M::mem_pestat] mean and std.dev: (440.03, 384.34) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2274) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 768300 reads in 256.616 CPU sec, 8.181 real sec [M::mem_process_seqs] Processed 769502 reads in 296.088 CPU sec, 9.470 real sec sorting block 10, #reads = 1084256 mem = 536881680 peak = 890105856 [M::process] read 767182 sequences (100000170 bp) in 3.052 CPU sec, 3.115 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 294448, 34, 56) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (159, 304, 668) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1686) [M::mem_pestat] mean and std.dev: (427.67, 362.85) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2195) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (111, 149, 203) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 387) [M::mem_pestat] mean and std.dev: (161.70, 67.55) [M::mem_pestat] low and high boundaries for proper pairs: (1, 479) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (321, 609, 1431) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3651) [M::mem_pestat] mean and std.dev: (802.37, 759.89) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4761) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (144, 303, 669) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1719) [M::mem_pestat] mean and std.dev: (400.48, 347.97) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2244) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 767830 sequences (100000163 bp) in 1.770 CPU sec, 1.767 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 293804, 39, 65) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (196, 395, 1764) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4900) [M::mem_pestat] mean and std.dev: (841.69, 1027.71) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6468) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (111, 148, 202) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384) [M::mem_pestat] mean and std.dev: (160.83, 66.76) [M::mem_pestat] low and high boundaries for proper pairs: (1, 475) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (204, 420, 1258) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3366) [M::mem_pestat] mean and std.dev: (737.95, 793.86) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4420) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (154, 302, 543) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1321) [M::mem_pestat] mean and std.dev: (319.41, 246.39) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1710) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 768120 reads in 251.546 CPU sec, 8.003 real sec sorting block 11, #reads = 1083720 mem = 536880874 peak = 890105856 [M::mem_process_seqs] Processed 768804 reads in 291.746 CPU sec, 9.309 real sec [M::process] read 767866 sequences (100000001 bp) in 2.838 CPU sec, 2.922 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 293344, 44, 60) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (159, 218, 761) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1965) [M::mem_pestat] mean and std.dev: (414.83, 422.53) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2567) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (111, 149, 203) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 387) [M::mem_pestat] mean and std.dev: (161.80, 67.14) [M::mem_pestat] low and high boundaries for proper pairs: (1, 479) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (171, 491, 1109) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2985) [M::mem_pestat] mean and std.dev: (625.38, 654.54) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3923) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (232, 375, 1115) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2881) [M::mem_pestat] mean and std.dev: (576.18, 530.10) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3764) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 768024 sequences (100000164 bp) in 2.430 CPU sec, 2.434 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 292730, 31, 68) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (144, 298, 949) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2559) [M::mem_pestat] mean and std.dev: (476.94, 464.00) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3364) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (111, 149, 202) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384) [M::mem_pestat] mean and std.dev: (161.38, 66.78) [M::mem_pestat] low and high boundaries for proper pairs: (1, 475) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (271, 882, 1296) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3346) [M::mem_pestat] mean and std.dev: (819.96, 751.47) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4371) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (173, 305, 594) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1436) [M::mem_pestat] mean and std.dev: (398.11, 336.14) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1857) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 767182 reads in 272.703 CPU sec, 8.667 real sec sorting block 12, #reads = 1080674 mem = 536881529 peak = 890105856 [M::mem_process_seqs] Processed 767830 reads in 315.476 CPU sec, 10.083 real sec sorting block 13, #reads = 1078538 mem = 536880872 peak = 929357824 [M::process] read 768062 sequences (100000138 bp) in 3.393 CPU sec, 3.478 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 293159, 42, 57) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (157, 323, 1170) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3196) [M::mem_pestat] mean and std.dev: (604.80, 731.06) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4209) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (111, 149, 202) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384) [M::mem_pestat] mean and std.dev: (161.29, 67.00) [M::mem_pestat] low and high boundaries for proper pairs: (1, 475) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (182, 645, 1074) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2858) [M::mem_pestat] mean and std.dev: (660.21, 612.80) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3750) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (195, 367, 1015) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2655) [M::mem_pestat] mean and std.dev: (586.60, 525.16) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3475) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 768376 sequences (100000082 bp) in 2.474 CPU sec, 2.479 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 293711, 33, 58) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (156, 220, 1191) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3261) [M::mem_pestat] mean and std.dev: (587.13, 662.63) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4296) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (111, 149, 202) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384) [M::mem_pestat] mean and std.dev: (161.33, 66.79) [M::mem_pestat] low and high boundaries for proper pairs: (1, 475) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (147, 575, 1201) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3309) [M::mem_pestat] mean and std.dev: (567.04, 591.94) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4363) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (217, 392, 1593) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4345) [M::mem_pestat] mean and std.dev: (750.88, 854.15) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5721) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 768024 reads in 283.460 CPU sec, 9.009 real sec sorting block 14, #reads = 1077314 mem = 536884713 peak = 929357824 [M::mem_process_seqs] Processed 767866 reads in 327.894 CPU sec, 10.458 real sec [M::process] read 775446 sequences (100000014 bp) in 3.613 CPU sec, 3.748 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 293464, 38, 48) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (160, 236, 702) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1786) [M::mem_pestat] mean and std.dev: (420.21, 388.50) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2328) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381) [M::mem_pestat] mean and std.dev: (160.69, 66.30) [M::mem_pestat] low and high boundaries for proper pairs: (1, 471) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (269, 698, 1937) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5273) [M::mem_pestat] mean and std.dev: (1105.00, 1274.84) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6941) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (185, 271, 1480) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4070) [M::mem_pestat] mean and std.dev: (633.86, 801.54) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5365) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 775706 sequences (100000185 bp) in 2.175 CPU sec, 2.184 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 293577, 34, 54) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (228, 331, 560) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1224) [M::mem_pestat] mean and std.dev: (362.21, 246.46) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1556) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (111, 148, 202) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384) [M::mem_pestat] mean and std.dev: (160.98, 66.58) [M::mem_pestat] low and high boundaries for proper pairs: (1, 475) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (185, 706, 1201) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3233) [M::mem_pestat] mean and std.dev: (759.28, 703.92) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4249) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (166, 282, 711) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1801) [M::mem_pestat] mean and std.dev: (435.74, 403.75) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2346) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 768376 reads in 285.022 CPU sec, 9.070 real sec sorting block 15, #reads = 1076480 mem = 536880167 peak = 929357824 [M::mem_process_seqs] Processed 768062 reads in 330.177 CPU sec, 10.544 real sec sorting block 16, #reads = 1075393 mem = 536879370 peak = 929357824 [M::process] read 774734 sequences (100000226 bp) in 3.354 CPU sec, 3.434 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 295363, 48, 67) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (183, 319, 758) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1908) [M::mem_pestat] mean and std.dev: (421.73, 369.68) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2483) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (109, 144, 195) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 367) [M::mem_pestat] mean and std.dev: (156.01, 63.11) [M::mem_pestat] low and high boundaries for proper pairs: (1, 453) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (187, 734, 2326) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6604) [M::mem_pestat] mean and std.dev: (942.24, 1001.57) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8743) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (186, 283, 920) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2388) [M::mem_pestat] mean and std.dev: (390.84, 323.68) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3122) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 774044 sequences (100000136 bp) in 2.407 CPU sec, 2.414 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 295832, 44, 69) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (194, 296, 1002) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2618) [M::mem_pestat] mean and std.dev: (512.66, 474.86) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3426) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (109, 144, 195) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 367) [M::mem_pestat] mean and std.dev: (156.15, 63.38) [M::mem_pestat] low and high boundaries for proper pairs: (1, 453) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (144, 491, 1458) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4086) [M::mem_pestat] mean and std.dev: (701.55, 846.00) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5400) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (209, 359, 788) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1946) [M::mem_pestat] mean and std.dev: (382.19, 267.53) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2525) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 775446 reads in 282.580 CPU sec, 8.991 real sec sorting block 17, #reads = 1079752 mem = 536878282 peak = 929357824 [M::mem_process_seqs] Processed 775706 reads in 325.803 CPU sec, 10.387 real sec [M::process] read 773600 sequences (100000169 bp) in 3.366 CPU sec, 3.462 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 296428, 43, 75) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (221, 666, 1068) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2762) [M::mem_pestat] mean and std.dev: (647.93, 533.67) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3609) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (109, 145, 196) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 370) [M::mem_pestat] mean and std.dev: (156.83, 63.82) [M::mem_pestat] low and high boundaries for proper pairs: (1, 457) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (227, 734, 1515) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4091) [M::mem_pestat] mean and std.dev: (726.97, 752.00) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5379) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (171, 297, 859) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2235) [M::mem_pestat] mean and std.dev: (475.34, 472.24) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2923) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 773230 sequences (100000156 bp) in 2.350 CPU sec, 2.350 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 296368, 40, 51) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (171, 220, 589) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1425) [M::mem_pestat] mean and std.dev: (317.02, 206.97) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1843) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (109, 145, 197) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 373) [M::mem_pestat] mean and std.dev: (157.52, 64.46) [M::mem_pestat] low and high boundaries for proper pairs: (1, 461) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (246, 504, 863) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2097) [M::mem_pestat] mean and std.dev: (580.57, 463.46) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2714) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (153, 282, 722) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1860) [M::mem_pestat] mean and std.dev: (435.75, 379.92) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2429) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 774734 reads in 264.624 CPU sec, 8.410 real sec sorting block 18, #reads = 1084326 mem = 536883974 peak = 929357824 [M::mem_process_seqs] Processed 774044 reads in 313.511 CPU sec, 10.021 real sec sorting block 19, #reads = 1087184 mem = 536879442 peak = 929357824 [M::process] read 772544 sequences (100000110 bp) in 3.103 CPU sec, 3.184 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 296330, 29, 57) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (153, 303, 509) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1221) [M::mem_pestat] mean and std.dev: (284.93, 148.52) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1577) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (109, 145, 197) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 373) [M::mem_pestat] mean and std.dev: (157.66, 64.52) [M::mem_pestat] low and high boundaries for proper pairs: (1, 461) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (80, 644, 1429) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4127) [M::mem_pestat] mean and std.dev: (864.11, 999.01) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5476) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (166, 269, 1010) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2698) [M::mem_pestat] mean and std.dev: (509.56, 547.53) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3542) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 772866 sequences (100000020 bp) in 2.457 CPU sec, 2.461 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 296618, 32, 65) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (160, 270, 766) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1978) [M::mem_pestat] mean and std.dev: (366.20, 278.50) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2584) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (109, 146, 197) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 373) [M::mem_pestat] mean and std.dev: (157.60, 64.25) [M::mem_pestat] low and high boundaries for proper pairs: (1, 461) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (168, 517, 1060) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2844) [M::mem_pestat] mean and std.dev: (608.74, 537.84) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3736) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (198, 543, 2666) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7602) [M::mem_pestat] mean and std.dev: (1105.59, 1347.85) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10070) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 773600 reads in 266.885 CPU sec, 8.507 real sec [M::mem_process_seqs] Processed 773230 reads in 191.546 CPU sec, 6.112 real sec sorting block 20, #reads = 1086775 mem = 536878942 peak = 929357824 [M::process] read 772014 sequences (100000248 bp) in 2.847 CPU sec, 2.924 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 296028, 32, 72) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (179, 307, 678) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1676) [M::mem_pestat] mean and std.dev: (424.94, 367.55) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2175) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (109, 146, 197) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 373) [M::mem_pestat] mean and std.dev: (157.77, 64.49) [M::mem_pestat] low and high boundaries for proper pairs: (1, 461) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (290, 1298, 1972) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5336) [M::mem_pestat] mean and std.dev: (1165.38, 990.69) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7018) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (218, 304, 692) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1640) [M::mem_pestat] mean and std.dev: (402.12, 313.25) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2114) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 772094 sequences (100000072 bp) in 2.250 CPU sec, 2.254 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 296474, 34, 58) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (212, 456, 1419) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3833) [M::mem_pestat] mean and std.dev: (754.48, 743.58) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5040) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 146, 198) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374) [M::mem_pestat] mean and std.dev: (158.19, 64.88) [M::mem_pestat] low and high boundaries for proper pairs: (1, 462) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (94, 242, 1154) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3274) [M::mem_pestat] mean and std.dev: (583.15, 676.11) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4334) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (172, 366, 744) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1888) [M::mem_pestat] mean and std.dev: (450.47, 369.09) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2460) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 772866 reads in 259.299 CPU sec, 8.251 real sec sorting block 21, #reads = 1087599 mem = 536877540 peak = 929357824 [M::mem_process_seqs] Processed 772544 reads in 298.912 CPU sec, 9.558 real sec [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 296517, 42, 49) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (157, 342, 1181) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3229) [M::mem_pestat] mean and std.dev: (593.30, 559.92) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4253) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 146, 199) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377) [M::mem_pestat] mean and std.dev: (158.78, 65.49) [M::mem_pestat] low and high boundaries for proper pairs: (1, 466) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (228, 678, 1417) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3795) [M::mem_pestat] mean and std.dev: (825.51, 759.30) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4984) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (182, 247, 847) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2177) [M::mem_pestat] mean and std.dev: (382.38, 359.23) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2842) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR sorting block 22, #reads = 1088064 mem = 536880943 peak = 929357824 [M::process] read 771124 sequences (100000211 bp) in 3.491 CPU sec, 3.593 real sec... [M::process] read 771182 sequences (100000070 bp) in 2.500 CPU sec, 2.495 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 296009, 41, 57) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (155, 365, 1386) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3848) [M::mem_pestat] mean and std.dev: (801.56, 964.65) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5079) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 146, 199) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377) [M::mem_pestat] mean and std.dev: (158.86, 65.54) [M::mem_pestat] low and high boundaries for proper pairs: (1, 466) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (341, 560, 2769) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7625) [M::mem_pestat] mean and std.dev: (1216.08, 1514.59) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10053) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (175, 381, 1323) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3619) [M::mem_pestat] mean and std.dev: (570.35, 563.67) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4767) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 772014 reads in 269.852 CPU sec, 8.611 real sec [M::mem_process_seqs] Processed 772094 reads in 197.040 CPU sec, 6.279 real sec sorting block 23, #reads = 1087207 mem = 536882794 peak = 929357824 [M::process] read 770930 sequences (100000139 bp) in 3.449 CPU sec, 3.540 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 295647, 39, 53) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (152, 318, 1195) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3281) [M::mem_pestat] mean and std.dev: (642.16, 728.16) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4324) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377) [M::mem_pestat] mean and std.dev: (159.08, 65.38) [M::mem_pestat] low and high boundaries for proper pairs: (1, 466) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (202, 688, 2604) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7408) [M::mem_pestat] mean and std.dev: (1475.69, 1749.61) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9810) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (176, 302, 749) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1895) [M::mem_pestat] mean and std.dev: (403.15, 314.79) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2468) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 771314 sequences (100000137 bp) in 2.478 CPU sec, 2.486 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 295914, 48, 61) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (209, 368, 809) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2009) [M::mem_pestat] mean and std.dev: (490.63, 434.48) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2609) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377) [M::mem_pestat] mean and std.dev: (158.96, 65.32) [M::mem_pestat] low and high boundaries for proper pairs: (1, 466) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (354, 522, 1442) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3618) [M::mem_pestat] mean and std.dev: (697.40, 579.72) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4706) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (205, 284, 1018) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2644) [M::mem_pestat] mean and std.dev: (493.82, 549.38) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3457) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 771124 reads in 267.439 CPU sec, 8.501 real sec sorting block 24, #reads = 1087290 mem = 536877526 peak = 929357824 [M::mem_process_seqs] Processed 771182 reads in 307.096 CPU sec, 9.809 real sec [M::process] read 771156 sequences (100000294 bp) in 3.213 CPU sec, 3.294 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 295608, 35, 71) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (143, 374, 1004) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2726) [M::mem_pestat] mean and std.dev: (580.12, 567.24) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3587) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380) [M::mem_pestat] mean and std.dev: (159.46, 65.77) [M::mem_pestat] low and high boundaries for proper pairs: (1, 470) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (328, 640, 1797) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4735) [M::mem_pestat] mean and std.dev: (1070.18, 1186.61) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6204) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (198, 341, 781) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1947) [M::mem_pestat] mean and std.dev: (450.73, 387.64) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2530) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 770118 sequences (100000140 bp) in 2.423 CPU sec, 2.430 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 295546, 28, 47) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (153, 346, 668) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1698) [M::mem_pestat] mean and std.dev: (428.98, 390.18) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2213) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377) [M::mem_pestat] mean and std.dev: (158.89, 65.21) [M::mem_pestat] low and high boundaries for proper pairs: (1, 466) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (266, 745, 2691) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7541) [M::mem_pestat] mean and std.dev: (1360.11, 1495.34) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9966) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (187, 380, 843) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2155) [M::mem_pestat] mean and std.dev: (474.63, 455.03) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2811) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 295227, 29, 71) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (170, 249, 539) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1277) [M::mem_pestat] mean and std.dev: (255.79, 163.04) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1646) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380) [M::mem_pestat] mean and std.dev: (159.47, 66.02) [M::mem_pestat] low and high boundaries for proper pairs: (1, 470) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (177, 620, 1476) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4074) [M::mem_pestat] mean and std.dev: (950.86, 965.95) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5373) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (226, 317, 681) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1591) [M::mem_pestat] mean and std.dev: (390.00, 286.63) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2046) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 770930 reads in 373.796 CPU sec, 12.269 real sec sorting block 25, #reads = 1085296 mem = 536881920 peak = 929357824 [M::mem_process_seqs] Processed 771314 reads in 299.868 CPU sec, 9.637 real sec [M::mem_process_seqs] Processed 771156 reads in 344.798 CPU sec, 11.083 real sec sorting block 26, #reads = 1085519 mem = 536881183 peak = 993153024 [M::process] read 768534 sequences (100000049 bp) in 3.339 CPU sec, 3.447 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 294947, 39, 69) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (255, 472, 1814) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4932) [M::mem_pestat] mean and std.dev: (940.48, 1131.69) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6491) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380) [M::mem_pestat] mean and std.dev: (159.79, 66.04) [M::mem_pestat] low and high boundaries for proper pairs: (1, 470) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (208, 769, 1797) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4975) [M::mem_pestat] mean and std.dev: (1035.72, 931.92) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6564) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (181, 426, 1317) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3589) [M::mem_pestat] mean and std.dev: (651.95, 776.40) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4725) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR sorting block 27, #reads = 1083277 mem = 536880896 peak = 993153024 [M::process] read 768752 sequences (100000012 bp) in 2.962 CPU sec, 3.075 real sec... [M::process] read 768902 sequences (100000116 bp) in 2.030 CPU sec, 2.034 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 293680, 35, 76) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (139, 282, 635) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1627) [M::mem_pestat] mean and std.dev: (372.55, 301.29) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2123) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381) [M::mem_pestat] mean and std.dev: (160.71, 66.38) [M::mem_pestat] low and high boundaries for proper pairs: (1, 471) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (172, 507, 1167) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3157) [M::mem_pestat] mean and std.dev: (782.97, 906.16) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4408) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (206, 319, 783) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1937) [M::mem_pestat] mean and std.dev: (422.77, 339.11) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2514) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 770118 reads in 275.926 CPU sec, 8.802 real sec [M::mem_process_seqs] Processed 768534 reads in 200.570 CPU sec, 6.401 real sec sorting block 28, #reads = 1082861 mem = 536878914 peak = 993153024 [M::process] read 768670 sequences (100000264 bp) in 3.171 CPU sec, 3.312 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 294387, 29, 70) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (156, 370, 755) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1953) [M::mem_pestat] mean and std.dev: (414.86, 376.16) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2552) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381) [M::mem_pestat] mean and std.dev: (160.41, 66.22) [M::mem_pestat] low and high boundaries for proper pairs: (1, 471) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (218, 563, 1391) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3737) [M::mem_pestat] mean and std.dev: (752.78, 706.74) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4910) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (223, 411, 1258) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3328) [M::mem_pestat] mean and std.dev: (698.08, 684.55) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4363) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 767944 sequences (100000096 bp) in 2.462 CPU sec, 2.470 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 293954, 32, 56) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (147, 355, 1192) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3282) [M::mem_pestat] mean and std.dev: (557.69, 619.47) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4327) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (111, 148, 200) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 378) [M::mem_pestat] mean and std.dev: (160.03, 65.69) [M::mem_pestat] low and high boundaries for proper pairs: (1, 467) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (220, 669, 1409) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3787) [M::mem_pestat] mean and std.dev: (642.43, 605.14) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4976) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (169, 313, 739) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1879) [M::mem_pestat] mean and std.dev: (320.46, 249.10) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2449) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 294177, 40, 74) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (170, 366, 1061) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2843) [M::mem_pestat] mean and std.dev: (542.37, 536.34) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3734) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381) [M::mem_pestat] mean and std.dev: (160.68, 66.36) [M::mem_pestat] low and high boundaries for proper pairs: (1, 471) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (205, 633, 1811) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5023) [M::mem_pestat] mean and std.dev: (934.60, 866.02) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6629) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (190, 361, 1035) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2725) [M::mem_pestat] mean and std.dev: (617.63, 627.15) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3570) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 768752 reads in 377.480 CPU sec, 12.229 real sec sorting block 29, #reads = 1081730 mem = 536877456 peak = 993153024 [M::mem_process_seqs] Processed 768902 reads in 302.114 CPU sec, 9.709 real sec [M::mem_process_seqs] Processed 768670 reads in 345.959 CPU sec, 11.150 real sec sorting block 30, #reads = 1080434 mem = 536877874 peak = 993153024 [M::process] read 768312 sequences (100000200 bp) in 3.115 CPU sec, 3.204 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 293613, 37, 57) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (153, 262, 901) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2397) [M::mem_pestat] mean and std.dev: (495.72, 518.80) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3145) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (111, 148, 202) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384) [M::mem_pestat] mean and std.dev: (161.12, 66.67) [M::mem_pestat] low and high boundaries for proper pairs: (1, 475) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (188, 540, 1371) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3737) [M::mem_pestat] mean and std.dev: (757.70, 679.75) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4920) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (158, 261, 561) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1367) [M::mem_pestat] mean and std.dev: (362.66, 290.75) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1770) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 768680 sequences (100000039 bp) in 2.920 CPU sec, 3.012 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 293901, 33, 67) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (137, 229, 827) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2207) [M::mem_pestat] mean and std.dev: (352.90, 296.46) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2897) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381) [M::mem_pestat] mean and std.dev: (160.66, 66.29) [M::mem_pestat] low and high boundaries for proper pairs: (1, 471) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (222, 1013, 2258) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6330) [M::mem_pestat] mean and std.dev: (1208.03, 1098.66) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8366) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (151, 212, 468) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1102) [M::mem_pestat] mean and std.dev: (280.10, 219.38) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1419) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 768654 sequences (100000247 bp) in 2.443 CPU sec, 2.448 real sec... [M::mem_process_seqs] Processed 767944 reads in 277.606 CPU sec, 8.840 real sec sorting block 31, #reads = 1080928 mem = 536884493 peak = 993153024 [M::mem_process_seqs] Processed 768312 reads in 200.279 CPU sec, 6.577 real sec sorting block 32, #reads = 1079433 mem = 536878622 peak = 993153024 [M::process] read 771714 sequences (100000145 bp) in 3.032 CPU sec, 3.129 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 294182, 32, 55) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (135, 318, 806) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2148) [M::mem_pestat] mean and std.dev: (444.20, 426.00) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2819) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381) [M::mem_pestat] mean and std.dev: (160.51, 66.27) [M::mem_pestat] low and high boundaries for proper pairs: (1, 471) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (227, 399, 636) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1454) [M::mem_pestat] mean and std.dev: (395.14, 272.91) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1863) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (196, 347, 911) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2341) [M::mem_pestat] mean and std.dev: (472.34, 386.04) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3056) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 776484 sequences (100000052 bp) in 2.094 CPU sec, 2.102 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 294160, 45, 63) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (148, 449, 1638) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4618) [M::mem_pestat] mean and std.dev: (855.62, 977.96) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6108) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 146, 198) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374) [M::mem_pestat] mean and std.dev: (158.31, 64.66) [M::mem_pestat] low and high boundaries for proper pairs: (1, 462) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (203, 727, 1668) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4598) [M::mem_pestat] mean and std.dev: (980.86, 980.24) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6063) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (169, 342, 1095) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2947) [M::mem_pestat] mean and std.dev: (595.31, 619.54) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3873) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 294121, 34, 60) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (161, 311, 678) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1712) [M::mem_pestat] mean and std.dev: (422.07, 353.63) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2229) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (111, 148, 202) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384) [M::mem_pestat] mean and std.dev: (160.96, 66.73) [M::mem_pestat] low and high boundaries for proper pairs: (1, 475) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (332, 974, 2251) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6089) [M::mem_pestat] mean and std.dev: (1319.82, 1323.73) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8008) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (167, 261, 448) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1010) [M::mem_pestat] mean and std.dev: (287.80, 192.06) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1291) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 768680 reads in 388.247 CPU sec, 12.617 real sec [M::mem_process_seqs] Processed 771714 reads in 314.098 CPU sec, 10.171 real sec sorting block 33, #reads = 1081107 mem = 536888155 peak = 993153024 [M::mem_process_seqs] Processed 768654 reads in 357.062 CPU sec, 11.559 real sec [M::process] read 774566 sequences (100000147 bp) in 3.399 CPU sec, 3.545 real sec... sorting block 34, #reads = 1079525 mem = 536877253 peak = 993153024 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 295824, 38, 59) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (159, 220, 912) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2418) [M::mem_pestat] mean and std.dev: (412.96, 429.28) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3171) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (108, 144, 194) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 366) [M::mem_pestat] mean and std.dev: (155.56, 62.80) [M::mem_pestat] low and high boundaries for proper pairs: (1, 452) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (276, 565, 1616) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4296) [M::mem_pestat] mean and std.dev: (962.84, 925.11) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5636) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (155, 276, 593) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1469) [M::mem_pestat] mean and std.dev: (369.05, 302.17) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1907) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 773444 sequences (100000215 bp) in 2.868 CPU sec, 2.962 real sec... [M::process] read 772816 sequences (100000056 bp) in 2.343 CPU sec, 2.358 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 296038, 40, 36) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (170, 308, 881) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2303) [M::mem_pestat] mean and std.dev: (497.02, 536.98) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3014) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (109, 145, 196) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 370) [M::mem_pestat] mean and std.dev: (156.85, 63.82) [M::mem_pestat] low and high boundaries for proper pairs: (1, 457) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (328, 665, 2714) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7486) [M::mem_pestat] mean and std.dev: (1480.69, 1699.86) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9872) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (244, 430, 886) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2170) [M::mem_pestat] mean and std.dev: (422.00, 292.04) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2812) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 776484 reads in 278.420 CPU sec, 8.892 real sec sorting block 35, #reads = 1081876 mem = 536881910 peak = 993153024 [M::mem_process_seqs] Processed 774566 reads in 203.496 CPU sec, 6.503 real sec [M::process] read 772868 sequences (100000133 bp) in 3.101 CPU sec, 3.213 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 296334, 42, 38) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (140, 204, 633) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1619) [M::mem_pestat] mean and std.dev: (298.72, 240.72) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2112) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (109, 146, 197) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 373) [M::mem_pestat] mean and std.dev: (157.60, 64.36) [M::mem_pestat] low and high boundaries for proper pairs: (1, 461) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (159, 769, 1136) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3090) [M::mem_pestat] mean and std.dev: (781.15, 683.82) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4067) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (173, 302, 887) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2315) [M::mem_pestat] mean and std.dev: (399.84, 388.44) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3029) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 772190 sequences (100000100 bp) in 2.381 CPU sec, 2.388 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 295612, 35, 54) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (170, 581, 842) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2186) [M::mem_pestat] mean and std.dev: (595.00, 530.29) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2858) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (109, 146, 198) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 376) [M::mem_pestat] mean and std.dev: (158.29, 65.11) [M::mem_pestat] low and high boundaries for proper pairs: (1, 465) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (125, 665, 918) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2504) [M::mem_pestat] mean and std.dev: (608.66, 526.03) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3297) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (159, 388, 1239) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3399) [M::mem_pestat] mean and std.dev: (713.14, 812.05) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4479) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 773444 reads in 268.518 CPU sec, 8.549 real sec sorting block 36, #reads = 1086159 mem = 536879618 peak = 993153024 [M::mem_process_seqs] Processed 772816 reads in 311.325 CPU sec, 10.009 real sec sorting block 37, #reads = 1085350 mem = 536889538 peak = 993153024 [M::process] read 772494 sequences (100000296 bp) in 3.150 CPU sec, 3.245 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 296122, 43, 51) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (174, 232, 667) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1653) [M::mem_pestat] mean and std.dev: (390.81, 346.94) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2146) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 146, 198) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374) [M::mem_pestat] mean and std.dev: (158.29, 64.80) [M::mem_pestat] low and high boundaries for proper pairs: (1, 462) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (210, 420, 1778) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4914) [M::mem_pestat] mean and std.dev: (955.07, 1166.39) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6482) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (166, 286, 673) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1687) [M::mem_pestat] mean and std.dev: (390.21, 353.13) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2194) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 772000 sequences (100000146 bp) in 2.512 CPU sec, 2.518 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 296507, 27, 71) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (153, 195, 512) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1230) [M::mem_pestat] mean and std.dev: (264.04, 205.42) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1589) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (109, 146, 198) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 376) [M::mem_pestat] mean and std.dev: (158.51, 65.30) [M::mem_pestat] low and high boundaries for proper pairs: (1, 465) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (90, 407, 1605) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4635) [M::mem_pestat] mean and std.dev: (775.46, 906.30) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6150) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (206, 351, 1921) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5351) [M::mem_pestat] mean and std.dev: (886.28, 1137.86) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7066) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 772190 reads in 271.404 CPU sec, 8.699 real sec [M::mem_process_seqs] Processed 772868 reads in 308.609 CPU sec, 10.093 real sec sorting block 38, #reads = 1086932 mem = 536888038 peak = 993153024 [M::process] read 771368 sequences (100000154 bp) in 3.273 CPU sec, 3.428 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 296159, 27, 66) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (186, 276, 1147) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3069) [M::mem_pestat] mean and std.dev: (553.38, 627.88) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4030) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 146, 198) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374) [M::mem_pestat] mean and std.dev: (158.25, 64.89) [M::mem_pestat] low and high boundaries for proper pairs: (1, 462) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (222, 572, 694) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1638) [M::mem_pestat] mean and std.dev: (487.27, 330.29) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2110) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (215, 328, 708) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1694) [M::mem_pestat] mean and std.dev: (413.60, 326.57) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2187) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 770836 sequences (100000207 bp) in 2.407 CPU sec, 2.433 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 295725, 39, 71) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (201, 411, 963) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2487) [M::mem_pestat] mean and std.dev: (643.72, 640.49) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3249) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 146, 198) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374) [M::mem_pestat] mean and std.dev: (158.35, 64.90) [M::mem_pestat] low and high boundaries for proper pairs: (1, 462) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (228, 676, 1052) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2700) [M::mem_pestat] mean and std.dev: (690.92, 554.13) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3524) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (174, 276, 663) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1641) [M::mem_pestat] mean and std.dev: (351.98, 256.58) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2130) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 295495, 41, 57) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (211, 417, 1395) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3763) [M::mem_pestat] mean and std.dev: (755.26, 778.63) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4947) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377) [M::mem_pestat] mean and std.dev: (158.93, 65.38) [M::mem_pestat] low and high boundaries for proper pairs: (1, 466) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (279, 546, 1064) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2634) [M::mem_pestat] mean and std.dev: (690.00, 529.68) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3419) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (182, 333, 983) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2585) [M::mem_pestat] mean and std.dev: (576.09, 606.81) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3386) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 772494 reads in 379.859 CPU sec, 12.326 real sec sorting block 39, #reads = 1085505 mem = 536885983 peak = 993153024 [M::mem_process_seqs] Processed 772000 reads in 303.494 CPU sec, 9.758 real sec [M::mem_process_seqs] Processed 771368 reads in 346.425 CPU sec, 11.147 real sec sorting block 40, #reads = 1085039 mem = 536884059 peak = 993153024 [M::process] read 772288 sequences (100000161 bp) in 3.440 CPU sec, 3.545 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 295737, 39, 55) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (183, 364, 1083) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2883) [M::mem_pestat] mean and std.dev: (545.40, 565.73) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3783) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380) [M::mem_pestat] mean and std.dev: (159.56, 65.98) [M::mem_pestat] low and high boundaries for proper pairs: (1, 470) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (169, 444, 1499) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4159) [M::mem_pestat] mean and std.dev: (715.84, 704.77) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5489) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (184, 315, 1642) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4558) [M::mem_pestat] mean and std.dev: (736.29, 823.16) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6016) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 770482 sequences (100000157 bp) in 2.842 CPU sec, 2.954 real sec... [M::process] read 769258 sequences (100000153 bp) in 2.167 CPU sec, 2.172 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 295289, 24, 54) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (140, 238, 637) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1631) [M::mem_pestat] mean and std.dev: (381.73, 377.61) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2128) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 146, 198) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374) [M::mem_pestat] mean and std.dev: (158.13, 64.63) [M::mem_pestat] low and high boundaries for proper pairs: (1, 462) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (178, 578, 1596) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4432) [M::mem_pestat] mean and std.dev: (1086.78, 1281.07) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6211) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (147, 372, 1364) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3798) [M::mem_pestat] mean and std.dev: (705.86, 780.40) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5015) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 770836 reads in 281.667 CPU sec, 9.000 real sec sorting block 41, #reads = 1086166 mem = 536882656 peak = 993153024 [M::mem_process_seqs] Processed 772288 reads in 200.472 CPU sec, 6.627 real sec sorting block 42, #reads = 1084793 mem = 536879155 peak = 1007792128 [M::process] read 768930 sequences (100000145 bp) in 2.878 CPU sec, 3.022 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 295184, 37, 61) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (157, 236, 655) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1651) [M::mem_pestat] mean and std.dev: (392.95, 363.54) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2149) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377) [M::mem_pestat] mean and std.dev: (159.38, 65.57) [M::mem_pestat] low and high boundaries for proper pairs: (1, 466) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (165, 501, 1394) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3852) [M::mem_pestat] mean and std.dev: (621.15, 664.32) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5081) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (201, 288, 695) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1683) [M::mem_pestat] mean and std.dev: (418.71, 366.28) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2177) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 768498 sequences (100000146 bp) in 2.356 CPU sec, 2.369 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 295424, 29, 52) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (139, 327, 762) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2008) [M::mem_pestat] mean and std.dev: (389.60, 345.20) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2631) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (111, 148, 200) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 378) [M::mem_pestat] mean and std.dev: (159.93, 65.72) [M::mem_pestat] low and high boundaries for proper pairs: (1, 467) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (284, 1011, 4619) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13289) [M::mem_pestat] mean and std.dev: (2131.45, 2616.07) [M::mem_pestat] low and high boundaries for proper pairs: (1, 17624) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (195, 375, 1657) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4581) [M::mem_pestat] mean and std.dev: (711.44, 864.42) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6043) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 294114, 33, 57) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (149, 225, 757) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1973) [M::mem_pestat] mean and std.dev: (435.50, 466.29) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2581) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381) [M::mem_pestat] mean and std.dev: (160.42, 66.24) [M::mem_pestat] low and high boundaries for proper pairs: (1, 471) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (169, 554, 1775) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4987) [M::mem_pestat] mean and std.dev: (958.78, 1003.81) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6593) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (145, 209, 1069) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2917) [M::mem_pestat] mean and std.dev: (556.07, 694.85) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3841) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 770482 reads in 378.729 CPU sec, 12.330 real sec [M::mem_process_seqs] Processed 769258 reads in 300.356 CPU sec, 9.671 real sec sorting block 43, #reads = 1084142 mem = 536877774 peak = 1007792128 [M::mem_process_seqs] Processed 768930 reads in 342.359 CPU sec, 11.036 real sec [M::process] read 768062 sequences (100000113 bp) in 3.308 CPU sec, 3.438 real sec... sorting block 44, #reads = 1083498 mem = 536887067 peak = 1007792128 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 294338, 48, 53) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (135, 284, 725) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1905) [M::mem_pestat] mean and std.dev: (389.51, 355.14) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2495) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381) [M::mem_pestat] mean and std.dev: (160.58, 66.19) [M::mem_pestat] low and high boundaries for proper pairs: (1, 471) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (195, 544, 1426) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3888) [M::mem_pestat] mean and std.dev: (755.14, 847.28) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5119) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (160, 430, 1197) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3271) [M::mem_pestat] mean and std.dev: (698.85, 714.32) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4308) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 768154 sequences (100000097 bp) in 2.997 CPU sec, 3.082 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 293792, 39, 65) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (145, 236, 810) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2140) [M::mem_pestat] mean and std.dev: (523.30, 541.18) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2805) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (111, 148, 202) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384) [M::mem_pestat] mean and std.dev: (161.05, 66.67) [M::mem_pestat] low and high boundaries for proper pairs: (1, 475) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (347, 804, 2762) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7592) [M::mem_pestat] mean and std.dev: (1695.57, 2083.29) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10029) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (168, 291, 1164) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3156) [M::mem_pestat] mean and std.dev: (616.43, 647.46) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4152) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 769020 sequences (100000069 bp) in 2.300 CPU sec, 2.302 real sec... [M::mem_process_seqs] Processed 768498 reads in 267.163 CPU sec, 8.517 real sec sorting block 45, #reads = 1081853 mem = 536881503 peak = 1007792128 [M::mem_process_seqs] Processed 768062 reads in 186.246 CPU sec, 6.098 real sec [M::process] read 768864 sequences (100000257 bp) in 2.853 CPU sec, 2.956 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 293592, 39, 66) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (175, 342, 1108) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2974) [M::mem_pestat] mean and std.dev: (542.68, 541.23) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3907) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (111, 148, 202) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384) [M::mem_pestat] mean and std.dev: (160.97, 66.48) [M::mem_pestat] low and high boundaries for proper pairs: (1, 475) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (237, 426, 896) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2214) [M::mem_pestat] mean and std.dev: (540.37, 493.19) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2873) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (178, 324, 742) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1870) [M::mem_pestat] mean and std.dev: (494.10, 458.80) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2434) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 767664 sequences (100000021 bp) in 2.251 CPU sec, 2.260 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 293733, 41, 53) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (156, 278, 935) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2493) [M::mem_pestat] mean and std.dev: (470.73, 484.52) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3272) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381) [M::mem_pestat] mean and std.dev: (160.37, 66.04) [M::mem_pestat] low and high boundaries for proper pairs: (1, 471) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (222, 457, 1099) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2853) [M::mem_pestat] mean and std.dev: (590.49, 571.66) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3730) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (185, 430, 1210) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3260) [M::mem_pestat] mean and std.dev: (730.90, 711.74) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4285) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 293317, 50, 48) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (157, 434, 1504) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4198) [M::mem_pestat] mean and std.dev: (874.03, 1049.38) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5545) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (111, 148, 200) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 378) [M::mem_pestat] mean and std.dev: (159.92, 65.54) [M::mem_pestat] low and high boundaries for proper pairs: (1, 467) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (128, 347, 650) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1694) [M::mem_pestat] mean and std.dev: (372.59, 322.94) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2216) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (173, 301, 669) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1661) [M::mem_pestat] mean and std.dev: (382.51, 292.90) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2157) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 768154 reads in 385.290 CPU sec, 12.495 real sec sorting block 46, #reads = 1081193 mem = 536880689 peak = 1007792128 [M::mem_process_seqs] Processed 769020 reads in 314.068 CPU sec, 10.090 real sec [M::mem_process_seqs] Processed 768864 reads in 357.656 CPU sec, 11.502 real sec sorting block 47, #reads = 1078756 mem = 536877581 peak = 1015099392 [M::process] read 768162 sequences (100000080 bp) in 3.370 CPU sec, 3.495 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 293433, 36, 60) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (153, 228, 515) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1239) [M::mem_pestat] mean and std.dev: (279.04, 228.36) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1601) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (111, 148, 202) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384) [M::mem_pestat] mean and std.dev: (161.09, 66.66) [M::mem_pestat] low and high boundaries for proper pairs: (1, 475) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (491, 977, 1874) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4640) [M::mem_pestat] mean and std.dev: (987.24, 787.34) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6023) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (172, 474, 1021) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2719) [M::mem_pestat] mean and std.dev: (612.46, 569.90) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3568) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR sorting block 48, #reads = 1078775 mem = 536888490 peak = 1015099392 [M::process] read 768640 sequences (100000128 bp) in 2.989 CPU sec, 3.115 real sec... [M::process] read 769212 sequences (100000263 bp) in 2.495 CPU sec, 2.497 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 293615, 47, 77) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (169, 302, 843) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2191) [M::mem_pestat] mean and std.dev: (511.52, 477.86) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2865) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (111, 148, 202) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384) [M::mem_pestat] mean and std.dev: (161.11, 66.75) [M::mem_pestat] low and high boundaries for proper pairs: (1, 475) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (346, 601, 1119) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2665) [M::mem_pestat] mean and std.dev: (635.14, 471.75) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3438) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (138, 234, 552) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1380) [M::mem_pestat] mean and std.dev: (274.56, 221.59) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1794) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 767664 reads in 281.663 CPU sec, 8.980 real sec [M::mem_process_seqs] Processed 768162 reads in 201.159 CPU sec, 6.401 real sec sorting block 49, #reads = 1079336 mem = 536877270 peak = 1015099392 [M::process] read 774920 sequences (100000158 bp) in 3.342 CPU sec, 3.448 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 294223, 31, 53) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (153, 284, 899) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2391) [M::mem_pestat] mean and std.dev: (495.16, 480.47) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3137) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381) [M::mem_pestat] mean and std.dev: (160.63, 66.49) [M::mem_pestat] low and high boundaries for proper pairs: (1, 471) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (153, 545, 1380) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3834) [M::mem_pestat] mean and std.dev: (643.15, 715.04) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5061) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (154, 304, 531) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1285) [M::mem_pestat] mean and std.dev: (303.96, 169.85) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1662) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 775764 sequences (100000061 bp) in 2.278 CPU sec, 2.284 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 293235, 24, 52) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (145, 303, 526) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1288) [M::mem_pestat] mean and std.dev: (357.90, 302.48) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1669) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 148, 201) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 383) [M::mem_pestat] mean and std.dev: (160.33, 66.38) [M::mem_pestat] low and high boundaries for proper pairs: (1, 474) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (231, 702, 2659) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7515) [M::mem_pestat] mean and std.dev: (1340.35, 1453.93) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9943) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (172, 331, 834) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2158) [M::mem_pestat] mean and std.dev: (485.08, 469.59) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2820) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 768640 reads in 277.096 CPU sec, 8.867 real sec sorting block 50, #reads = 1077541 mem = 536878284 peak = 1015099392 [M::mem_process_seqs] Processed 769212 reads in 317.748 CPU sec, 10.388 real sec [M::process] read 774546 sequences (100000046 bp) in 2.911 CPU sec, 2.960 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 295114, 46, 54) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (153, 363, 1289) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3561) [M::mem_pestat] mean and std.dev: (651.29, 792.27) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4697) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (109, 145, 195) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 367) [M::mem_pestat] mean and std.dev: (156.27, 63.32) [M::mem_pestat] low and high boundaries for proper pairs: (1, 453) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (170, 563, 827) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2141) [M::mem_pestat] mean and std.dev: (528.72, 436.47) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2798) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (189, 283, 1207) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3243) [M::mem_pestat] mean and std.dev: (675.36, 775.61) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4261) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 773080 sequences (100000012 bp) in 2.417 CPU sec, 2.428 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 296033, 37, 63) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (149, 257, 777) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2033) [M::mem_pestat] mean and std.dev: (406.07, 369.90) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2661) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (109, 145, 196) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 370) [M::mem_pestat] mean and std.dev: (156.83, 63.82) [M::mem_pestat] low and high boundaries for proper pairs: (1, 457) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (219, 916, 1587) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4323) [M::mem_pestat] mean and std.dev: (872.55, 786.71) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5691) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (160, 335, 844) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2212) [M::mem_pestat] mean and std.dev: (524.41, 531.42) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2896) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 295814, 33, 54) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (148, 319, 936) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2512) [M::mem_pestat] mean and std.dev: (480.11, 467.99) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3300) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (109, 144, 194) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 364) [M::mem_pestat] mean and std.dev: (155.71, 62.69) [M::mem_pestat] low and high boundaries for proper pairs: (1, 449) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (331, 691, 2532) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6934) [M::mem_pestat] mean and std.dev: (1235.45, 1482.89) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9135) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (204, 422, 930) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2382) [M::mem_pestat] mean and std.dev: (579.70, 540.85) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3108) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 774920 reads in 367.686 CPU sec, 11.923 real sec sorting block 51, #reads = 1076328 mem = 536880876 peak = 1015099392 [M::mem_process_seqs] Processed 774546 reads in 287.044 CPU sec, 9.215 real sec sorting block 52, #reads = 1077821 mem = 536878048 peak = 1056542720 [M::mem_process_seqs] Processed 775764 reads in 325.888 CPU sec, 10.451 real sec [M::process] read 772104 sequences (100000175 bp) in 2.825 CPU sec, 2.927 real sec... sorting block 53, #reads = 1085975 mem = 536878976 peak = 1056542720 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 295321, 40, 67) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (205, 347, 884) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2242) [M::mem_pestat] mean and std.dev: (501.56, 419.14) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2921) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (109, 146, 198) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 376) [M::mem_pestat] mean and std.dev: (158.05, 64.77) [M::mem_pestat] low and high boundaries for proper pairs: (1, 465) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (385, 702, 1409) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3457) [M::mem_pestat] mean and std.dev: (879.32, 796.69) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4481) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (167, 300, 1398) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3860) [M::mem_pestat] mean and std.dev: (671.35, 753.75) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5091) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 772254 sequences (100000160 bp) in 2.454 CPU sec, 2.510 real sec... [M::process] read 771616 sequences (100000252 bp) in 1.870 CPU sec, 1.877 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 296211, 30, 59) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (214, 399, 971) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2485) [M::mem_pestat] mean and std.dev: (530.16, 448.41) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3242) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 146, 198) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374) [M::mem_pestat] mean and std.dev: (157.99, 64.49) [M::mem_pestat] low and high boundaries for proper pairs: (1, 462) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (185, 574, 2555) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7295) [M::mem_pestat] mean and std.dev: (1509.80, 1941.94) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9665) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (229, 439, 1076) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2770) [M::mem_pestat] mean and std.dev: (613.24, 582.17) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3617) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 773080 reads in 246.191 CPU sec, 7.834 real sec [M::mem_process_seqs] Processed 772104 reads in 179.933 CPU sec, 5.741 real sec sorting block 54, #reads = 1086880 mem = 536878331 peak = 1056542720 [M::process] read 771140 sequences (100000079 bp) in 3.327 CPU sec, 3.403 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 295925, 33, 64) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (127, 297, 775) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2071) [M::mem_pestat] mean and std.dev: (440.88, 475.97) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2719) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 146, 198) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374) [M::mem_pestat] mean and std.dev: (158.30, 64.86) [M::mem_pestat] low and high boundaries for proper pairs: (1, 462) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (279, 1016, 3632) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10338) [M::mem_pestat] mean and std.dev: (1847.91, 2092.84) [M::mem_pestat] low and high boundaries for proper pairs: (1, 13691) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (171, 310, 773) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1977) [M::mem_pestat] mean and std.dev: (383.81, 335.69) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2579) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 770978 sequences (100000101 bp) in 2.149 CPU sec, 2.148 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 295857, 36, 61) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (149, 338, 600) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1502) [M::mem_pestat] mean and std.dev: (374.23, 307.68) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1953) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 146, 198) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374) [M::mem_pestat] mean and std.dev: (158.30, 64.68) [M::mem_pestat] low and high boundaries for proper pairs: (1, 462) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (600, 763, 1280) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2640) [M::mem_pestat] mean and std.dev: (757.81, 434.07) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3320) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (193, 361, 1012) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2650) [M::mem_pestat] mean and std.dev: (554.27, 566.52) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3469) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 772254 reads in 246.036 CPU sec, 7.811 real sec sorting block 55, #reads = 1086983 mem = 536878596 peak = 1056542720 [M::mem_process_seqs] Processed 771616 reads in 283.697 CPU sec, 9.089 real sec sorting block 56, #reads = 1085819 mem = 536877664 peak = 1056542720 [M::process] read 770208 sequences (100000216 bp) in 2.738 CPU sec, 2.799 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 295602, 26, 65) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (136, 196, 348) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 772) [M::mem_pestat] mean and std.dev: (210.59, 120.46) [M::mem_pestat] low and high boundaries for proper pairs: (1, 984) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377) [M::mem_pestat] mean and std.dev: (159.02, 65.45) [M::mem_pestat] low and high boundaries for proper pairs: (1, 466) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (61, 504, 858) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2452) [M::mem_pestat] mean and std.dev: (430.17, 378.82) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3249) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (234, 395, 931) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2325) [M::mem_pestat] mean and std.dev: (507.98, 419.38) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3022) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 770366 sequences (100000197 bp) in 2.319 CPU sec, 2.315 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 295351, 43, 48) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (146, 279, 1933) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5507) [M::mem_pestat] mean and std.dev: (686.74, 953.14) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7294) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377) [M::mem_pestat] mean and std.dev: (159.10, 65.34) [M::mem_pestat] low and high boundaries for proper pairs: (1, 466) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (291, 402, 1145) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2853) [M::mem_pestat] mean and std.dev: (628.78, 605.76) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3707) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (209, 430, 1169) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3089) [M::mem_pestat] mean and std.dev: (706.13, 662.45) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4049) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 771140 reads in 250.519 CPU sec, 8.007 real sec [M::mem_process_seqs] Processed 770978 reads in 288.575 CPU sec, 9.187 real sec sorting block 57, #reads = 1084624 mem = 536881072 peak = 1056542720 [M::process] read 771554 sequences (100000190 bp) in 3.095 CPU sec, 3.156 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 295372, 24, 57) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (150, 375, 883) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2349) [M::mem_pestat] mean and std.dev: (455.98, 411.85) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3082) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377) [M::mem_pestat] mean and std.dev: (159.21, 65.33) [M::mem_pestat] low and high boundaries for proper pairs: (1, 466) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (282, 938, 1115) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2781) [M::mem_pestat] mean and std.dev: (836.67, 625.09) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3614) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (178, 271, 1168) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3148) [M::mem_pestat] mean and std.dev: (568.75, 560.08) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4138) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 769842 sequences (100000276 bp) in 2.453 CPU sec, 2.461 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 294646, 44, 57) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (164, 224, 725) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1847) [M::mem_pestat] mean and std.dev: (395.10, 392.44) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2408) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380) [M::mem_pestat] mean and std.dev: (159.62, 65.90) [M::mem_pestat] low and high boundaries for proper pairs: (1, 470) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (208, 526, 1617) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4435) [M::mem_pestat] mean and std.dev: (939.42, 1062.88) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5844) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (176, 248, 799) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2045) [M::mem_pestat] mean and std.dev: (409.94, 380.17) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2668) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 770208 reads in 259.568 CPU sec, 8.240 real sec sorting block 58, #reads = 1083857 mem = 536883890 peak = 1056542720 [M::mem_process_seqs] Processed 770366 reads in 303.503 CPU sec, 9.680 real sec [M::process] read 768222 sequences (100000248 bp) in 2.956 CPU sec, 3.034 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 295232, 40, 70) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (194, 266, 775) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1937) [M::mem_pestat] mean and std.dev: (454.74, 433.86) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2518) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 146, 198) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374) [M::mem_pestat] mean and std.dev: (158.33, 64.57) [M::mem_pestat] low and high boundaries for proper pairs: (1, 462) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (204, 535, 1641) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4515) [M::mem_pestat] mean and std.dev: (890.26, 1065.51) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5952) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (180, 369, 842) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2166) [M::mem_pestat] mean and std.dev: (505.16, 485.22) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2828) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 767532 sequences (100000089 bp) in 2.420 CPU sec, 2.421 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 294325, 34, 51) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (146, 230, 911) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2441) [M::mem_pestat] mean and std.dev: (492.46, 525.26) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3206) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (111, 148, 202) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384) [M::mem_pestat] mean and std.dev: (160.92, 66.63) [M::mem_pestat] low and high boundaries for proper pairs: (1, 475) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (61, 180, 472) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1294) [M::mem_pestat] mean and std.dev: (226.62, 230.52) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1705) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (153, 321, 671) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1707) [M::mem_pestat] mean and std.dev: (373.33, 322.87) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2225) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 294781, 46, 73) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (156, 265, 781) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2031) [M::mem_pestat] mean and std.dev: (456.71, 426.79) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2656) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 148, 200) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380) [M::mem_pestat] mean and std.dev: (159.87, 65.84) [M::mem_pestat] low and high boundaries for proper pairs: (1, 470) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (246, 840, 2193) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6087) [M::mem_pestat] mean and std.dev: (1468.43, 1489.96) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8034) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (153, 295, 1447) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4035) [M::mem_pestat] mean and std.dev: (618.33, 690.07) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5329) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 771554 reads in 371.313 CPU sec, 11.850 real sec sorting block 59, #reads = 1081485 mem = 536887171 peak = 1056542720 [M::mem_process_seqs] Processed 768222 reads in 301.504 CPU sec, 9.679 real sec [M::mem_process_seqs] Processed 769842 reads in 341.768 CPU sec, 10.967 real sec sorting block 60, #reads = 1082281 mem = 536879322 peak = 1063575552 [M::process] read 766844 sequences (100000002 bp) in 3.471 CPU sec, 3.573 real sec... sorting block 61, #reads = 1084751 mem = 536877340 peak = 1063575552 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 293522, 33, 46) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (150, 256, 1102) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3006) [M::mem_pestat] mean and std.dev: (486.63, 594.57) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3958) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (111, 149, 203) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 387) [M::mem_pestat] mean and std.dev: (161.57, 67.09) [M::mem_pestat] low and high boundaries for proper pairs: (1, 479) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (167, 428, 1145) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3101) [M::mem_pestat] mean and std.dev: (513.62, 515.90) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4079) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (139, 303, 738) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1936) [M::mem_pestat] mean and std.dev: (394.37, 314.22) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2535) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 767482 sequences (100000027 bp) in 2.829 CPU sec, 2.885 real sec... [M::process] read 767506 sequences (100000261 bp) in 2.340 CPU sec, 2.348 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 293145, 38, 61) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (149, 346, 954) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2564) [M::mem_pestat] mean and std.dev: (453.21, 449.01) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3369) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (111, 149, 203) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 387) [M::mem_pestat] mean and std.dev: (161.95, 67.30) [M::mem_pestat] low and high boundaries for proper pairs: (1, 479) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (411, 499, 1507) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3699) [M::mem_pestat] mean and std.dev: (910.66, 987.58) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4861) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (205, 336, 942) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2416) [M::mem_pestat] mean and std.dev: (484.69, 415.88) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3153) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 767532 reads in 276.630 CPU sec, 8.805 real sec [M::mem_process_seqs] Processed 766844 reads in 200.026 CPU sec, 6.352 real sec sorting block 62, #reads = 1081138 mem = 536880676 peak = 1063575552 [M::process] read 767762 sequences (100000075 bp) in 3.150 CPU sec, 3.227 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 293412, 42, 78) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (145, 206, 770) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2020) [M::mem_pestat] mean and std.dev: (449.02, 458.01) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2645) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (111, 149, 202) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384) [M::mem_pestat] mean and std.dev: (161.25, 66.60) [M::mem_pestat] low and high boundaries for proper pairs: (1, 475) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (143, 578, 1316) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3662) [M::mem_pestat] mean and std.dev: (732.48, 659.80) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4835) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (178, 356, 1173) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3163) [M::mem_pestat] mean and std.dev: (581.22, 552.66) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4158) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 767714 sequences (100000074 bp) in 2.404 CPU sec, 2.413 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 293169, 26, 65) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (150, 266, 716) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1848) [M::mem_pestat] mean and std.dev: (396.80, 352.99) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2414) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (111, 149, 202) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384) [M::mem_pestat] mean and std.dev: (161.24, 66.61) [M::mem_pestat] low and high boundaries for proper pairs: (1, 475) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (191, 934, 1988) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5582) [M::mem_pestat] mean and std.dev: (703.90, 656.29) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7379) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (162, 417, 1060) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2856) [M::mem_pestat] mean and std.dev: (621.08, 615.62) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3754) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 767506 reads in 273.084 CPU sec, 8.677 real sec sorting block 63, #reads = 1078972 mem = 536877997 peak = 1063575552 [M::mem_process_seqs] Processed 767482 reads in 317.447 CPU sec, 10.115 real sec [M::process] read 767876 sequences (100000156 bp) in 3.277 CPU sec, 3.339 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 293414, 23, 62) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (183, 314, 1045) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2769) [M::mem_pestat] mean and std.dev: (559.27, 537.90) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3631) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (111, 148, 202) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384) [M::mem_pestat] mean and std.dev: (161.26, 66.79) [M::mem_pestat] low and high boundaries for proper pairs: (1, 475) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (224, 427, 1810) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4982) [M::mem_pestat] mean and std.dev: (884.38, 1154.90) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6568) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (173, 269, 506) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1172) [M::mem_pestat] mean and std.dev: (270.96, 183.32) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1505) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 768476 sequences (100000030 bp) in 2.420 CPU sec, 2.422 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 293412, 40, 59) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (182, 285, 1290) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3506) [M::mem_pestat] mean and std.dev: (636.11, 656.77) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4614) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381) [M::mem_pestat] mean and std.dev: (160.88, 66.21) [M::mem_pestat] low and high boundaries for proper pairs: (1, 471) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (284, 578, 1078) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2666) [M::mem_pestat] mean and std.dev: (659.43, 553.81) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3460) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (184, 305, 969) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2539) [M::mem_pestat] mean and std.dev: (477.33, 502.42) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3324) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 767762 reads in 269.421 CPU sec, 8.564 real sec sorting block 64, #reads = 1079615 mem = 536887641 peak = 1063575552 [M::mem_process_seqs] Processed 767714 reads in 313.620 CPU sec, 10.151 real sec sorting block 65, #reads = 1079748 mem = 536882135 peak = 1074462720 [M::process] read 767918 sequences (100000034 bp) in 2.702 CPU sec, 2.769 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 293513, 26, 67) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (139, 318, 1126) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3100) [M::mem_pestat] mean and std.dev: (600.32, 651.55) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4087) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (111, 148, 202) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384) [M::mem_pestat] mean and std.dev: (161.08, 66.63) [M::mem_pestat] low and high boundaries for proper pairs: (1, 475) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (480, 1176, 1814) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4482) [M::mem_pestat] mean and std.dev: (1021.18, 766.94) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5816) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (194, 310, 809) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2039) [M::mem_pestat] mean and std.dev: (451.00, 402.67) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2654) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 768018 sequences (100000261 bp) in 2.282 CPU sec, 2.288 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 293958, 48, 58) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (165, 261, 397) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 861) [M::mem_pestat] mean and std.dev: (233.78, 101.39) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1093) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381) [M::mem_pestat] mean and std.dev: (160.67, 66.43) [M::mem_pestat] low and high boundaries for proper pairs: (1, 471) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (290, 778, 1016) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2468) [M::mem_pestat] mean and std.dev: (694.91, 455.40) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3194) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (182, 350, 1206) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3254) [M::mem_pestat] mean and std.dev: (667.49, 745.90) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4278) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 767876 reads in 270.430 CPU sec, 8.746 real sec sorting block 66, #reads = 1079926 mem = 536883568 peak = 1074462720 [M::mem_process_seqs] Processed 768476 reads in 309.723 CPU sec, 9.899 real sec [M::process] read 776250 sequences (100000079 bp) in 3.058 CPU sec, 3.139 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 293912, 28, 64) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (168, 342, 987) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2625) [M::mem_pestat] mean and std.dev: (599.46, 663.73) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3444) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (111, 148, 202) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384) [M::mem_pestat] mean and std.dev: (161.08, 66.70) [M::mem_pestat] low and high boundaries for proper pairs: (1, 475) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (192, 933, 2072) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5832) [M::mem_pestat] mean and std.dev: (1338.86, 1455.18) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7712) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (167, 306, 827) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2147) [M::mem_pestat] mean and std.dev: (446.83, 390.53) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2807) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 778998 sequences (100000223 bp) in 2.521 CPU sec, 2.524 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (86, 293180, 46, 62) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (149, 328, 925) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2477) [M::mem_pestat] mean and std.dev: (534.70, 590.92) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3253) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381) [M::mem_pestat] mean and std.dev: (160.71, 66.24) [M::mem_pestat] low and high boundaries for proper pairs: (1, 471) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (216, 440, 1453) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3927) [M::mem_pestat] mean and std.dev: (754.07, 788.83) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5164) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (177, 290, 883) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2295) [M::mem_pestat] mean and std.dev: (516.00, 573.07) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3001) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 768018 reads in 280.900 CPU sec, 8.957 real sec sorting block 67, #reads = 1080664 mem = 536879370 peak = 1074462720 [M::mem_process_seqs] Processed 767918 reads in 318.423 CPU sec, 10.383 real sec sorting block 68, #reads = 1078685 mem = 536876137 peak = 1074462720 [M::process] read 777278 sequences (100000179 bp) in 3.028 CPU sec, 3.098 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 295712, 33, 72) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (189, 276, 964) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2514) [M::mem_pestat] mean and std.dev: (481.24, 506.70) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3289) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (109, 144, 194) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 364) [M::mem_pestat] mean and std.dev: (155.24, 62.26) [M::mem_pestat] low and high boundaries for proper pairs: (1, 449) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (246, 812, 2466) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6906) [M::mem_pestat] mean and std.dev: (1396.48, 1419.45) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9126) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (179, 278, 784) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1994) [M::mem_pestat] mean and std.dev: (425.86, 411.83) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2599) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 776746 sequences (100000006 bp) in 2.490 CPU sec, 2.494 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 296860, 34, 47) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (192, 357, 1240) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3336) [M::mem_pestat] mean and std.dev: (655.61, 765.58) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4384) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (108, 143, 193) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 363) [M::mem_pestat] mean and std.dev: (154.86, 62.19) [M::mem_pestat] low and high boundaries for proper pairs: (1, 448) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (111, 515, 1814) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5220) [M::mem_pestat] mean and std.dev: (913.41, 1042.08) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6923) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (182, 274, 875) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2261) [M::mem_pestat] mean and std.dev: (528.67, 431.32) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2954) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 296249, 52, 48) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (145, 340, 1259) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3487) [M::mem_pestat] mean and std.dev: (571.88, 619.03) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4601) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (108, 143, 191) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 357) [M::mem_pestat] mean and std.dev: (153.48, 60.85) [M::mem_pestat] low and high boundaries for proper pairs: (1, 440) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (220, 596, 3022) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8626) [M::mem_pestat] mean and std.dev: (1266.57, 1932.04) [M::mem_pestat] low and high boundaries for proper pairs: (1, 11428) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (179, 315, 769) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1949) [M::mem_pestat] mean and std.dev: (429.11, 347.17) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2539) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 776250 reads in 412.751 CPU sec, 13.384 real sec [M::mem_process_seqs] Processed 777278 reads in 322.664 CPU sec, 10.382 real sec sorting block 69, #reads = 1075619 mem = 536880004 peak = 1074462720 [M::mem_process_seqs] Processed 778998 reads in 371.167 CPU sec, 11.941 real sec [M::process] read 775582 sequences (100000093 bp) in 2.967 CPU sec, 3.070 real sec... sorting block 70, #reads = 1081972 mem = 536885071 peak = 1074462720 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 297757, 35, 42) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (176, 287, 589) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1415) [M::mem_pestat] mean and std.dev: (364.14, 319.77) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1828) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (108, 144, 193) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 363) [M::mem_pestat] mean and std.dev: (155.04, 62.14) [M::mem_pestat] low and high boundaries for proper pairs: (1, 448) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (249, 601, 1649) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4449) [M::mem_pestat] mean and std.dev: (822.00, 975.83) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5849) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (233, 468, 941) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2357) [M::mem_pestat] mean and std.dev: (475.80, 376.30) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3065) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 774572 sequences (100000198 bp) in 2.895 CPU sec, 2.957 real sec... [M::process] read 774208 sequences (100000165 bp) in 2.370 CPU sec, 2.371 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 297018, 37, 63) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (181, 230, 736) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1846) [M::mem_pestat] mean and std.dev: (366.71, 295.01) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2401) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (109, 144, 195) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 367) [M::mem_pestat] mean and std.dev: (155.91, 62.92) [M::mem_pestat] low and high boundaries for proper pairs: (1, 453) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (320, 564, 4731) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13553) [M::mem_pestat] mean and std.dev: (2246.59, 3249.36) [M::mem_pestat] low and high boundaries for proper pairs: (1, 17964) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (184, 354, 876) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2260) [M::mem_pestat] mean and std.dev: (458.33, 404.35) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2952) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 776746 reads in 271.258 CPU sec, 8.624 real sec sorting block 71, #reads = 1083240 mem = 536881897 peak = 1074462720 [M::mem_process_seqs] Processed 775582 reads in 190.122 CPU sec, 6.078 real sec [M::process] read 773678 sequences (100000029 bp) in 3.009 CPU sec, 3.107 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 297001, 34, 53) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (171, 293, 722) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1824) [M::mem_pestat] mean and std.dev: (444.85, 407.66) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2375) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (109, 145, 195) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 367) [M::mem_pestat] mean and std.dev: (156.49, 63.30) [M::mem_pestat] low and high boundaries for proper pairs: (1, 453) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (340, 743, 1432) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3616) [M::mem_pestat] mean and std.dev: (724.52, 661.68) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4708) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (189, 334, 856) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2190) [M::mem_pestat] mean and std.dev: (536.00, 490.16) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2857) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 773104 sequences (100000063 bp) in 2.470 CPU sec, 2.466 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 296369, 34, 39) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (154, 276, 567) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1393) [M::mem_pestat] mean and std.dev: (337.73, 307.32) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1806) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (109, 145, 196) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 370) [M::mem_pestat] mean and std.dev: (156.93, 63.77) [M::mem_pestat] low and high boundaries for proper pairs: (1, 457) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (176, 623, 1002) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2654) [M::mem_pestat] mean and std.dev: (769.33, 769.09) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3846) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (226, 285, 645) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1483) [M::mem_pestat] mean and std.dev: (332.24, 231.77) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1902) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 774572 reads in 267.220 CPU sec, 8.518 real sec sorting block 72, #reads = 1085013 mem = 536879102 peak = 1074462720 [M::process] read 772850 sequences (100000025 bp) in 2.391 CPU sec, 2.404 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 297321, 37, 55) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (157, 248, 767) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1987) [M::mem_pestat] mean and std.dev: (376.12, 352.48) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2597) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (109, 145, 196) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 370) [M::mem_pestat] mean and std.dev: (157.00, 63.54) [M::mem_pestat] low and high boundaries for proper pairs: (1, 457) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (176, 841, 1206) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3266) [M::mem_pestat] mean and std.dev: (727.74, 558.15) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4296) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (197, 267, 1287) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3467) [M::mem_pestat] mean and std.dev: (614.02, 686.63) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4557) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 773678 reads in 156.291 CPU sec, 5.191 real sec sorting block 73, #reads = 1087582 mem = 536883938 peak = 1074462720 [M::mem_process_seqs] Processed 774208 reads in 496.971 CPU sec, 16.074 real sec sorting block 74, #reads = 1083492 mem = 536880365 peak = 1074462720 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 296467, 25, 44) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (153, 304, 730) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1884) [M::mem_pestat] mean and std.dev: (393.90, 327.39) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2461) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 146, 197) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371) [M::mem_pestat] mean and std.dev: (157.39, 63.78) [M::mem_pestat] low and high boundaries for proper pairs: (1, 458) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (92, 383, 2111) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6149) [M::mem_pestat] mean and std.dev: (990.25, 1425.08) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8168) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (216, 423, 716) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1716) [M::mem_pestat] mean and std.dev: (434.11, 338.34) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2216) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 772902 sequences (100000279 bp) in 2.685 CPU sec, 2.792 real sec... [M::process] read 773698 sequences (100000180 bp) in 2.029 CPU sec, 2.032 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 296290, 29, 72) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (183, 235, 930) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2424) [M::mem_pestat] mean and std.dev: (440.96, 424.60) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3171) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 146, 197) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371) [M::mem_pestat] mean and std.dev: (157.55, 63.95) [M::mem_pestat] low and high boundaries for proper pairs: (1, 458) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (217, 456, 1163) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3055) [M::mem_pestat] mean and std.dev: (639.61, 599.25) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4001) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (196, 376, 1477) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4039) [M::mem_pestat] mean and std.dev: (758.19, 840.91) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5320) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 773104 reads in 419.255 CPU sec, 13.576 real sec [M::mem_process_seqs] Processed 772850 reads in 192.366 CPU sec, 6.162 real sec sorting block 75, #reads = 1085860 mem = 536883412 peak = 1074462720 [M::process] read 773230 sequences (100000170 bp) in 2.696 CPU sec, 2.796 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 296837, 49, 57) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (219, 468, 1086) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2820) [M::mem_pestat] mean and std.dev: (641.44, 608.77) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3687) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (109, 145, 196) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 370) [M::mem_pestat] mean and std.dev: (156.93, 63.58) [M::mem_pestat] low and high boundaries for proper pairs: (1, 457) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (272, 636, 2400) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6656) [M::mem_pestat] mean and std.dev: (1101.51, 1487.96) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8784) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (199, 317, 861) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2185) [M::mem_pestat] mean and std.dev: (417.12, 335.13) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2847) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 773090 sequences (100000294 bp) in 2.298 CPU sec, 2.299 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 296685, 22, 49) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (169, 264, 780) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2002) [M::mem_pestat] mean and std.dev: (465.33, 476.57) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2613) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 146, 196) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 368) [M::mem_pestat] mean and std.dev: (157.20, 63.69) [M::mem_pestat] low and high boundaries for proper pairs: (1, 454) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (298, 500, 1098) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2698) [M::mem_pestat] mean and std.dev: (631.81, 490.88) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3498) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (160, 234, 1760) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4960) [M::mem_pestat] mean and std.dev: (735.76, 936.78) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6560) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 773698 reads in 263.828 CPU sec, 8.392 real sec sorting block 76, #reads = 1085625 mem = 536882262 peak = 1074462720 [M::mem_process_seqs] Processed 772902 reads in 307.430 CPU sec, 9.805 real sec [M::process] read 772512 sequences (100000014 bp) in 3.171 CPU sec, 3.256 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 296068, 31, 65) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (164, 265, 571) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1385) [M::mem_pestat] mean and std.dev: (318.84, 228.73) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1792) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 146, 196) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 368) [M::mem_pestat] mean and std.dev: (157.17, 63.48) [M::mem_pestat] low and high boundaries for proper pairs: (1, 454) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (63, 414, 963) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2763) [M::mem_pestat] mean and std.dev: (477.14, 523.57) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3663) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (153, 289, 610) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1524) [M::mem_pestat] mean and std.dev: (386.26, 302.80) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1981) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 772802 sequences (100000182 bp) in 2.440 CPU sec, 2.439 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 296908, 30, 53) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (180, 334, 1041) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2763) [M::mem_pestat] mean and std.dev: (511.29, 481.94) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3624) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 146, 196) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 368) [M::mem_pestat] mean and std.dev: (157.10, 63.61) [M::mem_pestat] low and high boundaries for proper pairs: (1, 454) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (227, 465, 986) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2504) [M::mem_pestat] mean and std.dev: (563.89, 496.32) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3263) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (163, 243, 653) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1633) [M::mem_pestat] mean and std.dev: (357.70, 333.55) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2123) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 773090 reads in 267.606 CPU sec, 8.506 real sec sorting block 77, #reads = 1084187 mem = 536878458 peak = 1074462720 [M::mem_process_seqs] Processed 773230 reads in 304.696 CPU sec, 9.789 real sec sorting block 78, #reads = 1081811 mem = 536882864 peak = 1133600768 [M::process] read 772214 sequences (100000027 bp) in 3.185 CPU sec, 3.254 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 296059, 28, 42) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (160, 341, 909) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2407) [M::mem_pestat] mean and std.dev: (468.09, 445.69) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3156) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 145, 197) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371) [M::mem_pestat] mean and std.dev: (157.39, 63.86) [M::mem_pestat] low and high boundaries for proper pairs: (1, 458) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (109, 354, 2635) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7687) [M::mem_pestat] mean and std.dev: (1351.50, 1963.83) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10213) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (239, 649, 1192) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3098) [M::mem_pestat] mean and std.dev: (691.39, 642.28) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4051) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 771272 sequences (100000142 bp) in 2.419 CPU sec, 2.421 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 296119, 26, 60) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (199, 336, 689) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1669) [M::mem_pestat] mean and std.dev: (429.00, 334.68) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2159) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 146, 197) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371) [M::mem_pestat] mean and std.dev: (157.73, 64.00) [M::mem_pestat] low and high boundaries for proper pairs: (1, 458) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (227, 894, 2046) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5684) [M::mem_pestat] mean and std.dev: (918.33, 909.23) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7503) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (204, 460, 887) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2253) [M::mem_pestat] mean and std.dev: (592.23, 501.11) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2936) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 772802 reads in 265.977 CPU sec, 8.523 real sec sorting block 79, #reads = 1083590 mem = 536882340 peak = 1133600768 [M::process] read 770980 sequences (100000081 bp) in 2.479 CPU sec, 2.491 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 295938, 37, 55) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (165, 421, 970) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2580) [M::mem_pestat] mean and std.dev: (543.53, 477.91) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3385) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 146, 197) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371) [M::mem_pestat] mean and std.dev: (157.90, 64.30) [M::mem_pestat] low and high boundaries for proper pairs: (1, 458) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (184, 664, 1588) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4396) [M::mem_pestat] mean and std.dev: (919.06, 990.70) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5800) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (206, 340, 1017) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2639) [M::mem_pestat] mean and std.dev: (564.79, 478.35) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3450) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 772214 reads in 155.518 CPU sec, 4.951 real sec [M::mem_process_seqs] Processed 772512 reads in 499.631 CPU sec, 16.008 real sec sorting block 80, #reads = 1082313 mem = 536889681 peak = 1133600768 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 294665, 42, 52) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (147, 340, 1033) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2805) [M::mem_pestat] mean and std.dev: (632.35, 752.97) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3691) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 146, 198) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374) [M::mem_pestat] mean and std.dev: (158.27, 64.40) [M::mem_pestat] low and high boundaries for proper pairs: (1, 462) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (167, 567, 1284) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3518) [M::mem_pestat] mean and std.dev: (567.00, 498.86) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4635) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (199, 326, 843) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2131) [M::mem_pestat] mean and std.dev: (479.70, 463.84) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2775) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 770328 sequences (100000111 bp) in 3.026 CPU sec, 3.093 real sec... [M::process] read 769908 sequences (100000240 bp) in 2.499 CPU sec, 2.500 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 294191, 52, 77) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (167, 261, 800) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2066) [M::mem_pestat] mean and std.dev: (466.89, 455.31) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2699) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 147, 198) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374) [M::mem_pestat] mean and std.dev: (158.67, 64.69) [M::mem_pestat] low and high boundaries for proper pairs: (1, 462) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (231, 612, 1340) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3558) [M::mem_pestat] mean and std.dev: (669.43, 612.41) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4667) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (230, 309, 1166) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3038) [M::mem_pestat] mean and std.dev: (493.72, 521.09) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3974) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 771272 reads in 426.743 CPU sec, 13.563 real sec sorting block 81, #reads = 1082387 mem = 536889350 peak = 1133600768 [M::mem_process_seqs] Processed 770980 reads in 196.618 CPU sec, 6.380 real sec sorting block 82, #reads = 1078781 mem = 536879920 peak = 1133600768 [M::process] read 769500 sequences (100000260 bp) in 3.254 CPU sec, 3.374 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 294873, 33, 57) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (159, 259, 691) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1755) [M::mem_pestat] mean and std.dev: (412.90, 399.11) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2287) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377) [M::mem_pestat] mean and std.dev: (159.04, 65.12) [M::mem_pestat] low and high boundaries for proper pairs: (1, 466) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (159, 511, 1535) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4287) [M::mem_pestat] mean and std.dev: (812.65, 873.25) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5663) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (184, 365, 891) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2305) [M::mem_pestat] mean and std.dev: (485.65, 377.36) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3012) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 770000 sequences (100000140 bp) in 2.294 CPU sec, 2.297 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 294500, 37, 58) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (169, 378, 736) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1870) [M::mem_pestat] mean and std.dev: (452.27, 361.03) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2437) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377) [M::mem_pestat] mean and std.dev: (159.46, 65.35) [M::mem_pestat] low and high boundaries for proper pairs: (1, 466) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (248, 763, 1316) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3452) [M::mem_pestat] mean and std.dev: (812.54, 693.70) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4520) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (137, 320, 742) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1952) [M::mem_pestat] mean and std.dev: (376.16, 343.48) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2557) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 770328 reads in 278.846 CPU sec, 8.993 real sec [M::mem_process_seqs] Processed 769908 reads in 316.400 CPU sec, 10.211 real sec sorting block 83, #reads = 1079873 mem = 536878646 peak = 1133600768 [M::process] read 769622 sequences (100000150 bp) in 2.907 CPU sec, 2.973 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 293520, 29, 73) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (161, 332, 607) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1499) [M::mem_pestat] mean and std.dev: (383.45, 336.06) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1945) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (111, 147, 200) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 378) [M::mem_pestat] mean and std.dev: (159.77, 65.57) [M::mem_pestat] low and high boundaries for proper pairs: (1, 467) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (179, 346, 1614) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4484) [M::mem_pestat] mean and std.dev: (489.67, 562.54) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5919) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (181, 513, 1086) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2896) [M::mem_pestat] mean and std.dev: (617.20, 542.59) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3801) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 784024 sequences (100000097 bp) in 2.562 CPU sec, 2.564 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 294112, 37, 69) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (202, 365, 827) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2077) [M::mem_pestat] mean and std.dev: (455.66, 357.10) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2702) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377) [M::mem_pestat] mean and std.dev: (159.32, 65.27) [M::mem_pestat] low and high boundaries for proper pairs: (1, 466) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (306, 737, 1400) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3588) [M::mem_pestat] mean and std.dev: (920.53, 836.35) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4682) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (179, 288, 1081) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2885) [M::mem_pestat] mean and std.dev: (484.90, 532.59) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3787) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 769500 reads in 271.656 CPU sec, 8.622 real sec sorting block 84, #reads = 1079591 mem = 536878140 peak = 1133600768 [M::mem_process_seqs] Processed 770000 reads in 317.160 CPU sec, 10.090 real sec [M::process] read 784180 sequences (100000228 bp) in 3.031 CPU sec, 3.116 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 297322, 27, 70) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (149, 265, 982) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2648) [M::mem_pestat] mean and std.dev: (571.80, 605.05) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3481) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (107, 140, 187) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 347) [M::mem_pestat] mean and std.dev: (150.65, 58.95) [M::mem_pestat] low and high boundaries for proper pairs: (1, 427) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (240, 510, 961) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2403) [M::mem_pestat] mean and std.dev: (561.58, 520.08) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3124) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (179, 285, 767) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1943) [M::mem_pestat] mean and std.dev: (408.89, 345.83) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2531) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 782518 sequences (100000043 bp) in 2.190 CPU sec, 2.192 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 293964, 43, 63) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (160, 325, 1025) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2755) [M::mem_pestat] mean and std.dev: (489.37, 549.55) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3620) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377) [M::mem_pestat] mean and std.dev: (159.48, 65.23) [M::mem_pestat] low and high boundaries for proper pairs: (1, 466) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (268, 684, 1113) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2803) [M::mem_pestat] mean and std.dev: (671.42, 549.33) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3648) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (179, 251, 637) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1553) [M::mem_pestat] mean and std.dev: (316.07, 254.68) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2011) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 784024 reads in 308.962 CPU sec, 9.843 real sec sorting block 85, #reads = 1076187 mem = 536879530 peak = 1133600768 [M::mem_process_seqs] Processed 769622 reads in 356.438 CPU sec, 11.379 real sec sorting block 86, #reads = 1069689 mem = 536884706 peak = 1154023424 [M::process] read 781124 sequences (100000183 bp) in 3.002 CPU sec, 3.051 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 297819, 31, 51) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (163, 292, 765) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1969) [M::mem_pestat] mean and std.dev: (371.72, 318.44) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2571) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (106, 140, 187) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 349) [M::mem_pestat] mean and std.dev: (150.58, 58.97) [M::mem_pestat] low and high boundaries for proper pairs: (1, 430) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (174, 328, 877) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2283) [M::mem_pestat] mean and std.dev: (532.07, 537.80) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2986) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (213, 289, 548) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1218) [M::mem_pestat] mean and std.dev: (320.07, 176.13) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1553) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 780426 sequences (100000176 bp) in 2.575 CPU sec, 2.575 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 298716, 22, 47) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (174, 489, 1420) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3912) [M::mem_pestat] mean and std.dev: (684.98, 640.45) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5158) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (107, 141, 188) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 350) [M::mem_pestat] mean and std.dev: (151.26, 59.21) [M::mem_pestat] low and high boundaries for proper pairs: (1, 431) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (142, 471, 1844) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5248) [M::mem_pestat] mean and std.dev: (865.52, 953.50) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6950) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (183, 273, 811) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2067) [M::mem_pestat] mean and std.dev: (469.33, 415.38) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2695) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 784180 reads in 317.721 CPU sec, 10.108 real sec sorting block 87, #reads = 1067385 mem = 536885705 peak = 1154023424 [M::mem_process_seqs] Processed 782518 reads in 371.790 CPU sec, 11.840 real sec [M::process] read 777412 sequences (100000155 bp) in 3.285 CPU sec, 3.374 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 298165, 36, 76) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (153, 326, 1366) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3792) [M::mem_pestat] mean and std.dev: (807.05, 957.58) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5005) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (107, 142, 189) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 353) [M::mem_pestat] mean and std.dev: (152.24, 59.89) [M::mem_pestat] low and high boundaries for proper pairs: (1, 435) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (145, 650, 1298) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3604) [M::mem_pestat] mean and std.dev: (729.58, 785.29) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4757) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (162, 272, 1076) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2904) [M::mem_pestat] mean and std.dev: (474.65, 552.09) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3818) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 777244 sequences (100000278 bp) in 2.226 CPU sec, 2.227 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 298061, 41, 60) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (154, 318, 875) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2317) [M::mem_pestat] mean and std.dev: (400.06, 323.50) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3038) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (107, 142, 190) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 356) [M::mem_pestat] mean and std.dev: (152.95, 60.70) [M::mem_pestat] low and high boundaries for proper pairs: (1, 439) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (265, 594, 1863) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5059) [M::mem_pestat] mean and std.dev: (1140.26, 1250.11) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6657) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (151, 287, 829) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2185) [M::mem_pestat] mean and std.dev: (494.80, 507.71) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2863) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 781124 reads in 312.369 CPU sec, 9.955 real sec sorting block 88, #reads = 1072353 mem = 536878533 peak = 1154023424 [M::mem_process_seqs] Processed 780426 reads in 372.916 CPU sec, 11.934 real sec sorting block 89, #reads = 1075702 mem = 536883715 peak = 1158770688 [M::process] read 776282 sequences (100000040 bp) in 3.396 CPU sec, 3.462 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 297106, 41, 46) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (172, 310, 857) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2227) [M::mem_pestat] mean and std.dev: (504.72, 435.98) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2912) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (108, 144, 193) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 363) [M::mem_pestat] mean and std.dev: (154.74, 61.85) [M::mem_pestat] low and high boundaries for proper pairs: (1, 448) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (219, 415, 856) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2130) [M::mem_pestat] mean and std.dev: (508.53, 374.06) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2767) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (162, 273, 676) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1704) [M::mem_pestat] mean and std.dev: (311.13, 286.28) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2218) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 775192 sequences (100000156 bp) in 2.084 CPU sec, 2.093 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 297624, 44, 47) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (152, 275, 565) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1391) [M::mem_pestat] mean and std.dev: (334.81, 271.48) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1804) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (108, 143, 193) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 363) [M::mem_pestat] mean and std.dev: (154.65, 61.77) [M::mem_pestat] low and high boundaries for proper pairs: (1, 448) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (192, 538, 2232) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6312) [M::mem_pestat] mean and std.dev: (1073.93, 1183.00) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8352) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (194, 302, 707) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1733) [M::mem_pestat] mean and std.dev: (409.45, 357.49) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2246) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 777412 reads in 307.074 CPU sec, 9.798 real sec sorting block 90, #reads = 1074037 mem = 536884131 peak = 1158770688 [M::mem_process_seqs] Processed 777244 reads in 356.392 CPU sec, 11.595 real sec [M::process] read 774722 sequences (100000049 bp) in 3.544 CPU sec, 3.638 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 297521, 24, 45) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (166, 287, 845) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2203) [M::mem_pestat] mean and std.dev: (429.33, 454.14) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2882) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (109, 144, 194) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 364) [M::mem_pestat] mean and std.dev: (155.54, 62.52) [M::mem_pestat] low and high boundaries for proper pairs: (1, 449) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (381, 565, 1273) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3057) [M::mem_pestat] mean and std.dev: (733.95, 699.32) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3949) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (176, 306, 1007) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2669) [M::mem_pestat] mean and std.dev: (540.00, 600.61) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3500) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 774344 sequences (100000014 bp) in 2.517 CPU sec, 2.521 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 296812, 33, 57) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (161, 433, 1098) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2972) [M::mem_pestat] mean and std.dev: (621.27, 574.47) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3909) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (109, 144, 194) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 364) [M::mem_pestat] mean and std.dev: (155.94, 62.64) [M::mem_pestat] low and high boundaries for proper pairs: (1, 449) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (258, 617, 1097) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2775) [M::mem_pestat] mean and std.dev: (672.42, 523.35) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3614) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (170, 426, 940) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2480) [M::mem_pestat] mean and std.dev: (567.81, 556.32) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3250) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 776282 reads in 297.209 CPU sec, 9.652 real sec sorting block 91, #reads = 1078876 mem = 536879532 peak = 1158770688 [M::process] read 772842 sequences (100000022 bp) in 2.589 CPU sec, 2.599 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 296867, 45, 52) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (183, 462, 1273) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3453) [M::mem_pestat] mean and std.dev: (786.72, 851.16) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4543) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (109, 145, 195) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 367) [M::mem_pestat] mean and std.dev: (156.17, 62.87) [M::mem_pestat] low and high boundaries for proper pairs: (1, 453) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (213, 534, 1105) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2889) [M::mem_pestat] mean and std.dev: (624.60, 520.49) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3781) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (181, 303, 870) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2248) [M::mem_pestat] mean and std.dev: (507.33, 452.21) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2937) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 774722 reads in 168.488 CPU sec, 5.495 real sec sorting block 92, #reads = 1080557 mem = 536892317 peak = 1158770688 [M::mem_process_seqs] Processed 775192 reads in 558.678 CPU sec, 18.186 real sec [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 296491, 29, 67) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (133, 189, 349) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 781) [M::mem_pestat] mean and std.dev: (242.31, 170.78) [M::mem_pestat] low and high boundaries for proper pairs: (1, 997) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (109, 145, 195) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 367) [M::mem_pestat] mean and std.dev: (156.33, 63.07) [M::mem_pestat] low and high boundaries for proper pairs: (1, 453) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (460, 709, 2680) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7120) [M::mem_pestat] mean and std.dev: (1292.63, 1373.69) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9340) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (203, 503, 1392) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3770) [M::mem_pestat] mean and std.dev: (786.16, 798.99) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4959) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR sorting block 93, #reads = 1079545 mem = 536884968 peak = 1158770688 [M::process] read 773502 sequences (100000254 bp) in 2.906 CPU sec, 3.014 real sec... [M::process] read 773038 sequences (100000194 bp) in 2.220 CPU sec, 2.222 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 295963, 31, 46) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (140, 221, 817) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2171) [M::mem_pestat] mean and std.dev: (473.64, 487.46) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2848) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 146, 197) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371) [M::mem_pestat] mean and std.dev: (157.50, 63.86) [M::mem_pestat] low and high boundaries for proper pairs: (1, 458) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (195, 453, 1685) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4665) [M::mem_pestat] mean and std.dev: (803.18, 1020.10) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6155) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (194, 428, 1258) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3386) [M::mem_pestat] mean and std.dev: (516.55, 487.96) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4450) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 774344 reads in 453.903 CPU sec, 14.610 real sec [M::mem_process_seqs] Processed 772842 reads in 210.519 CPU sec, 6.730 real sec sorting block 94, #reads = 1081298 mem = 536882272 peak = 1158770688 [M::process] read 772344 sequences (100000235 bp) in 3.130 CPU sec, 3.248 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 296265, 22, 45) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (142, 369, 1504) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4228) [M::mem_pestat] mean and std.dev: (659.19, 745.52) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5590) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (109, 145, 196) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 370) [M::mem_pestat] mean and std.dev: (157.01, 63.45) [M::mem_pestat] low and high boundaries for proper pairs: (1, 457) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (646, 933, 1360) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2788) [M::mem_pestat] mean and std.dev: (908.90, 353.54) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3502) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (219, 386, 1069) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2769) [M::mem_pestat] mean and std.dev: (602.32, 551.67) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3619) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 772240 sequences (100000125 bp) in 2.460 CPU sec, 2.461 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 295822, 35, 75) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (203, 330, 1293) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3473) [M::mem_pestat] mean and std.dev: (651.81, 744.74) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4563) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (109, 146, 196) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 370) [M::mem_pestat] mean and std.dev: (157.31, 63.64) [M::mem_pestat] low and high boundaries for proper pairs: (1, 457) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (205, 439, 1404) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3802) [M::mem_pestat] mean and std.dev: (714.94, 803.18) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5001) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (177, 405, 1038) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2760) [M::mem_pestat] mean and std.dev: (616.69, 621.79) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3621) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 773502 reads in 286.565 CPU sec, 9.119 real sec [M::mem_process_seqs] Processed 773038 reads in 332.063 CPU sec, 10.628 real sec sorting block 95, #reads = 1078951 mem = 536885849 peak = 1158770688 [M::process] read 771246 sequences (100000030 bp) in 3.086 CPU sec, 3.165 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 295380, 32, 57) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (174, 577, 1814) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5094) [M::mem_pestat] mean and std.dev: (1058.51, 1256.66) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6734) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 146, 197) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371) [M::mem_pestat] mean and std.dev: (157.31, 63.54) [M::mem_pestat] low and high boundaries for proper pairs: (1, 458) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (180, 993, 1968) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5544) [M::mem_pestat] mean and std.dev: (997.21, 985.75) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7332) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (159, 284, 891) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2355) [M::mem_pestat] mean and std.dev: (460.00, 467.07) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3087) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 770548 sequences (100000117 bp) in 2.008 CPU sec, 2.012 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 295665, 38, 57) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (158, 290, 500) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1184) [M::mem_pestat] mean and std.dev: (307.41, 207.81) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1526) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 146, 197) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371) [M::mem_pestat] mean and std.dev: (157.61, 63.90) [M::mem_pestat] low and high boundaries for proper pairs: (1, 458) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (282, 548, 909) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2163) [M::mem_pestat] mean and std.dev: (571.34, 431.35) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2790) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (177, 323, 1095) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2931) [M::mem_pestat] mean and std.dev: (485.06, 526.03) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3849) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 295105, 38, 66) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (147, 284, 972) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2622) [M::mem_pestat] mean and std.dev: (443.33, 455.34) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3447) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 146, 197) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371) [M::mem_pestat] mean and std.dev: (157.96, 63.98) [M::mem_pestat] low and high boundaries for proper pairs: (1, 458) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (265, 541, 802) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1876) [M::mem_pestat] mean and std.dev: (526.44, 402.88) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2413) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (190, 325, 800) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2020) [M::mem_pestat] mean and std.dev: (448.90, 397.98) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2630) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 772344 reads in 367.287 CPU sec, 11.763 real sec sorting block 96, #reads = 1081538 mem = 536877768 peak = 1158770688 [M::mem_process_seqs] Processed 772240 reads in 284.866 CPU sec, 9.160 real sec sorting block 97, #reads = 1081103 mem = 536882887 peak = 1158770688 [M::mem_process_seqs] Processed 771246 reads in 313.908 CPU sec, 10.085 real sec [M::process] read 770348 sequences (100000279 bp) in 2.958 CPU sec, 3.056 real sec... sorting block 98, #reads = 1079006 mem = 536882188 peak = 1158770688 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 294480, 35, 59) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (159, 317, 994) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2664) [M::mem_pestat] mean and std.dev: (561.08, 572.63) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3499) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377) [M::mem_pestat] mean and std.dev: (158.94, 64.85) [M::mem_pestat] low and high boundaries for proper pairs: (1, 466) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (214, 657, 868) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2176) [M::mem_pestat] mean and std.dev: (540.66, 400.15) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2830) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (238, 388, 877) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2155) [M::mem_pestat] mean and std.dev: (521.04, 471.08) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2794) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 770128 sequences (100000262 bp) in 2.612 CPU sec, 2.637 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 294815, 31, 48) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (157, 299, 882) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2332) [M::mem_pestat] mean and std.dev: (473.43, 464.72) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3057) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 147, 198) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374) [M::mem_pestat] mean and std.dev: (158.51, 64.42) [M::mem_pestat] low and high boundaries for proper pairs: (1, 462) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (133, 860, 1629) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4621) [M::mem_pestat] mean and std.dev: (1071.37, 1124.55) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6117) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (203, 364, 987) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2555) [M::mem_pestat] mean and std.dev: (586.33, 607.39) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3339) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 769952 sequences (100000213 bp) in 2.410 CPU sec, 2.411 real sec... [M::mem_process_seqs] Processed 770548 reads in 264.754 CPU sec, 8.397 real sec [M::process] read 770168 sequences (100000226 bp) in 2.793 CPU sec, 2.806 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 294088, 43, 52) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (151, 228, 588) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1462) [M::mem_pestat] mean and std.dev: (336.27, 286.30) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1899) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377) [M::mem_pestat] mean and std.dev: (158.92, 64.71) [M::mem_pestat] low and high boundaries for proper pairs: (1, 466) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (183, 416, 869) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2241) [M::mem_pestat] mean and std.dev: (495.88, 409.39) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2927) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (173, 253, 827) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2135) [M::mem_pestat] mean and std.dev: (473.94, 483.16) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2789) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 770128 reads in 166.228 CPU sec, 5.299 real sec sorting block 99, #reads = 1079308 mem = 536878558 peak = 1158770688 [M::mem_process_seqs] Processed 770348 reads in 418.352 CPU sec, 13.335 real sec [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 293929, 44, 77) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (162, 310, 795) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2061) [M::mem_pestat] mean and std.dev: (402.39, 343.14) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2694) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377) [M::mem_pestat] mean and std.dev: (159.25, 65.10) [M::mem_pestat] low and high boundaries for proper pairs: (1, 466) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (209, 470, 1198) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3176) [M::mem_pestat] mean and std.dev: (629.48, 659.76) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4165) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (207, 350, 801) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1989) [M::mem_pestat] mean and std.dev: (432.53, 354.57) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2583) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR sorting block 100, #reads = 1077448 mem = 536882420 peak = 1158770688 [M::process] read 778486 sequences (100000118 bp) in 3.112 CPU sec, 3.352 real sec... [M::process] read 778080 sequences (100000196 bp) in 2.490 CPU sec, 2.494 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 293865, 31, 68) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (149, 292, 1290) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3572) [M::mem_pestat] mean and std.dev: (575.65, 661.18) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4713) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377) [M::mem_pestat] mean and std.dev: (158.94, 65.07) [M::mem_pestat] low and high boundaries for proper pairs: (1, 466) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (187, 355, 565) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1321) [M::mem_pestat] mean and std.dev: (339.52, 254.81) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1699) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (158, 264, 785) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2039) [M::mem_pestat] mean and std.dev: (423.82, 404.50) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2666) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 769952 reads in 456.154 CPU sec, 14.531 real sec [M::mem_process_seqs] Processed 770168 reads in 223.509 CPU sec, 7.284 real sec sorting block 101, #reads = 1078211 mem = 536884591 peak = 1158770688 [M::process] read 775322 sequences (100000162 bp) in 3.308 CPU sec, 3.415 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 297219, 40, 56) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (153, 347, 1028) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2778) [M::mem_pestat] mean and std.dev: (552.89, 556.58) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3653) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (108, 143, 192) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 360) [M::mem_pestat] mean and std.dev: (154.15, 61.57) [M::mem_pestat] low and high boundaries for proper pairs: (1, 444) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (353, 833, 3516) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9842) [M::mem_pestat] mean and std.dev: (2161.47, 2877.52) [M::mem_pestat] low and high boundaries for proper pairs: (1, 13672) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (272, 597, 1541) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4079) [M::mem_pestat] mean and std.dev: (803.04, 639.69) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5348) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 774692 sequences (100000172 bp) in 2.530 CPU sec, 2.525 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 295403, 38, 55) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (157, 351, 763) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1975) [M::mem_pestat] mean and std.dev: (417.15, 413.85) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2581) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (108, 143, 191) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 357) [M::mem_pestat] mean and std.dev: (153.63, 60.98) [M::mem_pestat] low and high boundaries for proper pairs: (1, 440) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (206, 652, 1753) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4847) [M::mem_pestat] mean and std.dev: (975.23, 1125.79) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6394) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (152, 272, 1139) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3113) [M::mem_pestat] mean and std.dev: (514.92, 627.95) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4100) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 778080 reads in 294.891 CPU sec, 9.528 real sec sorting block 102, #reads = 1073650 mem = 536883157 peak = 1158770688 [M::process] read 774090 sequences (100000198 bp) in 2.559 CPU sec, 2.569 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 297024, 41, 57) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (145, 307, 908) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2434) [M::mem_pestat] mean and std.dev: (550.50, 533.02) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3197) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (109, 144, 195) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 367) [M::mem_pestat] mean and std.dev: (156.03, 62.95) [M::mem_pestat] low and high boundaries for proper pairs: (1, 453) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (366, 808, 2378) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6402) [M::mem_pestat] mean and std.dev: (1282.44, 1334.94) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8414) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (190, 315, 741) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1843) [M::mem_pestat] mean and std.dev: (451.33, 399.72) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2394) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 775322 reads in 160.723 CPU sec, 5.151 real sec sorting block 103, #reads = 1084784 mem = 536880346 peak = 1158770688 [M::mem_process_seqs] Processed 778486 reads in 559.574 CPU sec, 18.069 real sec [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 296370, 43, 54) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (178, 253, 788) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2008) [M::mem_pestat] mean and std.dev: (393.64, 378.02) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2618) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (109, 145, 195) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 367) [M::mem_pestat] mean and std.dev: (156.32, 63.09) [M::mem_pestat] low and high boundaries for proper pairs: (1, 453) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (342, 638, 1632) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4212) [M::mem_pestat] mean and std.dev: (915.79, 1004.55) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5502) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (215, 411, 918) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2324) [M::mem_pestat] mean and std.dev: (544.04, 524.31) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3027) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 773392 sequences (100000009 bp) in 3.097 CPU sec, 3.276 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 296533, 32, 59) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (162, 399, 1494) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4158) [M::mem_pestat] mean and std.dev: (849.89, 943.46) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5490) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (109, 145, 196) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 370) [M::mem_pestat] mean and std.dev: (156.76, 63.49) [M::mem_pestat] low and high boundaries for proper pairs: (1, 457) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (198, 676, 1759) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4881) [M::mem_pestat] mean and std.dev: (1117.55, 1180.06) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6442) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (149, 249, 742) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1928) [M::mem_pestat] mean and std.dev: (440.04, 465.29) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2521) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 772386 sequences (100000101 bp) in 2.426 CPU sec, 2.430 real sec... [M::mem_process_seqs] Processed 774692 reads in 429.985 CPU sec, 13.722 real sec sorting block 104, #reads = 1067394 mem = 536885905 peak = 1158770688 [M::mem_process_seqs] Processed 774090 reads in 200.020 CPU sec, 6.348 real sec sorting block 105, #reads = 1083215 mem = 536878056 peak = 1158770688 [M::process] read 772068 sequences (100000107 bp) in 3.179 CPU sec, 3.247 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 296202, 25, 38) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (164, 396, 829) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2159) [M::mem_pestat] mean and std.dev: (521.49, 485.21) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2824) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (109, 146, 197) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 373) [M::mem_pestat] mean and std.dev: (157.57, 64.22) [M::mem_pestat] low and high boundaries for proper pairs: (1, 461) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (210, 841, 2494) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7062) [M::mem_pestat] mean and std.dev: (1252.54, 1440.27) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9346) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (211, 322, 1147) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3019) [M::mem_pestat] mean and std.dev: (634.66, 673.44) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3955) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 771452 sequences (100000085 bp) in 2.479 CPU sec, 2.489 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 296344, 30, 56) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (219, 357, 743) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1791) [M::mem_pestat] mean and std.dev: (422.76, 344.58) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2315) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 146, 197) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371) [M::mem_pestat] mean and std.dev: (157.97, 64.38) [M::mem_pestat] low and high boundaries for proper pairs: (1, 458) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (139, 696, 1393) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3901) [M::mem_pestat] mean and std.dev: (671.63, 585.11) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5155) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (173, 295, 739) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1871) [M::mem_pestat] mean and std.dev: (412.04, 391.84) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2437) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 773392 reads in 268.215 CPU sec, 8.516 real sec sorting block 106, #reads = 1085249 mem = 536878403 peak = 1158770688 [M::mem_process_seqs] Processed 772386 reads in 308.465 CPU sec, 10.016 real sec [M::process] read 771414 sequences (100000039 bp) in 3.412 CPU sec, 3.488 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 296508, 32, 53) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (138, 253, 825) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2199) [M::mem_pestat] mean and std.dev: (398.55, 394.90) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2886) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 146, 198) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374) [M::mem_pestat] mean and std.dev: (158.25, 64.66) [M::mem_pestat] low and high boundaries for proper pairs: (1, 462) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (165, 307, 859) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2247) [M::mem_pestat] mean and std.dev: (487.47, 484.61) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2941) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (133, 250, 841) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2257) [M::mem_pestat] mean and std.dev: (448.48, 429.09) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2965) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 771648 sequences (100000192 bp) in 2.463 CPU sec, 2.472 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 295496, 35, 55) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (145, 197, 448) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1054) [M::mem_pestat] mean and std.dev: (276.51, 234.99) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1357) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 147, 198) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374) [M::mem_pestat] mean and std.dev: (158.50, 64.64) [M::mem_pestat] low and high boundaries for proper pairs: (1, 462) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (50, 357, 1745) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5135) [M::mem_pestat] mean and std.dev: (901.89, 1108.38) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6830) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (186, 261, 918) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2382) [M::mem_pestat] mean and std.dev: (527.37, 467.37) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3114) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 772068 reads in 265.684 CPU sec, 8.695 real sec sorting block 107, #reads = 1082991 mem = 536879678 peak = 1158770688 [M::mem_process_seqs] Processed 771452 reads in 303.240 CPU sec, 10.088 real sec sorting block 108, #reads = 1083250 mem = 536879929 peak = 1158770688 [M::process] read 771872 sequences (100000094 bp) in 3.206 CPU sec, 3.295 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 295555, 31, 62) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (174, 505, 1071) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2865) [M::mem_pestat] mean and std.dev: (661.53, 614.28) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3762) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 147, 198) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374) [M::mem_pestat] mean and std.dev: (158.61, 64.68) [M::mem_pestat] low and high boundaries for proper pairs: (1, 462) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (156, 446, 951) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2541) [M::mem_pestat] mean and std.dev: (518.68, 481.95) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3336) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (171, 336, 666) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1656) [M::mem_pestat] mean and std.dev: (447.98, 377.29) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2151) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 772538 sequences (100000009 bp) in 2.250 CPU sec, 2.260 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 296162, 40, 53) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (178, 242, 822) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2110) [M::mem_pestat] mean and std.dev: (415.40, 379.70) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2754) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 146, 198) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374) [M::mem_pestat] mean and std.dev: (158.24, 64.52) [M::mem_pestat] low and high boundaries for proper pairs: (1, 462) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (134, 618, 1165) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3227) [M::mem_pestat] mean and std.dev: (667.54, 586.27) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4258) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (153, 243, 726) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1872) [M::mem_pestat] mean and std.dev: (389.06, 347.53) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2445) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 296310, 36, 55) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (144, 224, 1093) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2991) [M::mem_pestat] mean and std.dev: (427.47, 486.90) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3940) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 146, 198) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374) [M::mem_pestat] mean and std.dev: (158.21, 64.45) [M::mem_pestat] low and high boundaries for proper pairs: (1, 462) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (220, 662, 1126) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2938) [M::mem_pestat] mean and std.dev: (740.32, 675.66) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3844) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (254, 486, 1194) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3074) [M::mem_pestat] mean and std.dev: (640.31, 509.28) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4014) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 771414 reads in 373.092 CPU sec, 12.082 real sec [M::mem_process_seqs] Processed 771648 reads in 289.051 CPU sec, 9.265 real sec sorting block 109, #reads = 1084172 mem = 536888191 peak = 1158770688 [M::mem_process_seqs] Processed 771872 reads in 324.661 CPU sec, 10.420 real sec [M::process] read 771352 sequences (100000234 bp) in 2.552 CPU sec, 2.626 real sec... sorting block 110, #reads = 1084005 mem = 536878931 peak = 1158770688 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 296154, 32, 60) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (217, 384, 1246) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3304) [M::mem_pestat] mean and std.dev: (608.36, 559.44) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4333) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 146, 197) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371) [M::mem_pestat] mean and std.dev: (157.53, 63.94) [M::mem_pestat] low and high boundaries for proper pairs: (1, 458) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (314, 642, 1389) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3539) [M::mem_pestat] mean and std.dev: (769.10, 651.31) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4614) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (204, 381, 858) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2166) [M::mem_pestat] mean and std.dev: (554.73, 547.45) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2820) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 770756 sequences (100000228 bp) in 2.176 CPU sec, 2.232 real sec... [M::process] read 770920 sequences (100000189 bp) in 1.730 CPU sec, 1.737 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 295673, 41, 66) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (175, 461, 892) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2326) [M::mem_pestat] mean and std.dev: (572.98, 523.61) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3043) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 147, 198) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374) [M::mem_pestat] mean and std.dev: (158.40, 64.41) [M::mem_pestat] low and high boundaries for proper pairs: (1, 462) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (134, 499, 1245) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3467) [M::mem_pestat] mean and std.dev: (597.58, 524.12) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4578) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (177, 414, 1155) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3111) [M::mem_pestat] mean and std.dev: (672.19, 736.75) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4089) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 772538 reads in 230.747 CPU sec, 7.352 real sec sorting block 111, #reads = 1083728 mem = 536880262 peak = 1158770688 [M::mem_process_seqs] Processed 771352 reads in 166.999 CPU sec, 5.324 real sec [M::process] read 770196 sequences (100000028 bp) in 3.124 CPU sec, 3.184 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 295260, 41, 62) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (144, 287, 770) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2022) [M::mem_pestat] mean and std.dev: (440.49, 421.01) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2648) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 147, 198) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374) [M::mem_pestat] mean and std.dev: (158.64, 64.72) [M::mem_pestat] low and high boundaries for proper pairs: (1, 462) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (172, 386, 983) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2605) [M::mem_pestat] mean and std.dev: (433.49, 393.73) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3416) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (173, 316, 1178) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3188) [M::mem_pestat] mean and std.dev: (605.10, 647.82) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4193) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 770548 sequences (100000095 bp) in 2.390 CPU sec, 2.398 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 294394, 36, 51) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (182, 230, 545) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1271) [M::mem_pestat] mean and std.dev: (343.80, 276.67) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1634) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 147, 198) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374) [M::mem_pestat] mean and std.dev: (158.60, 64.59) [M::mem_pestat] low and high boundaries for proper pairs: (1, 462) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (112, 887, 1189) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3343) [M::mem_pestat] mean and std.dev: (735.71, 624.78) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4420) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (243, 405, 1332) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3510) [M::mem_pestat] mean and std.dev: (711.85, 734.28) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4599) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 770920 reads in 231.432 CPU sec, 7.344 real sec sorting block 112, #reads = 1081937 mem = 536885166 peak = 1158770688 [M::mem_process_seqs] Processed 770756 reads in 267.581 CPU sec, 8.515 real sec sorting block 113, #reads = 1081973 mem = 536886049 peak = 1158770688 [M::process] read 770132 sequences (100000280 bp) in 2.417 CPU sec, 2.469 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 294103, 42, 56) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (225, 584, 1550) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4200) [M::mem_pestat] mean and std.dev: (706.77, 749.20) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5525) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377) [M::mem_pestat] mean and std.dev: (158.92, 64.86) [M::mem_pestat] low and high boundaries for proper pairs: (1, 466) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (252, 484, 1108) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2820) [M::mem_pestat] mean and std.dev: (612.90, 540.41) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3676) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (215, 384, 1052) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2726) [M::mem_pestat] mean and std.dev: (584.25, 541.13) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3563) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 769710 sequences (100000174 bp) in 1.900 CPU sec, 1.905 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 294016, 45, 71) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (198, 480, 1053) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2763) [M::mem_pestat] mean and std.dev: (586.75, 578.97) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3618) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 147, 198) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374) [M::mem_pestat] mean and std.dev: (158.73, 64.53) [M::mem_pestat] low and high boundaries for proper pairs: (1, 462) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (198, 346, 1507) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4125) [M::mem_pestat] mean and std.dev: (569.52, 675.81) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5434) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (181, 321, 1371) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3751) [M::mem_pestat] mean and std.dev: (750.40, 909.32) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4941) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 770548 reads in 221.933 CPU sec, 7.067 real sec sorting block 114, #reads = 1078091 mem = 536877566 peak = 1158770688 [M::mem_process_seqs] Processed 770196 reads in 250.851 CPU sec, 8.003 real sec [M::process] read 769352 sequences (100000047 bp) in 2.522 CPU sec, 2.582 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 293934, 26, 39) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (163, 213, 430) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 964) [M::mem_pestat] mean and std.dev: (240.34, 131.48) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1231) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377) [M::mem_pestat] mean and std.dev: (158.94, 64.73) [M::mem_pestat] low and high boundaries for proper pairs: (1, 466) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (166, 453, 1446) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4006) [M::mem_pestat] mean and std.dev: (645.38, 673.26) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5286) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (304, 419, 778) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1726) [M::mem_pestat] mean and std.dev: (459.29, 312.42) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2200) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 770238 sequences (100000229 bp) in 1.740 CPU sec, 1.742 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 293584, 37, 76) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (172, 316, 633) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1555) [M::mem_pestat] mean and std.dev: (324.59, 249.21) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2016) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377) [M::mem_pestat] mean and std.dev: (159.22, 64.96) [M::mem_pestat] low and high boundaries for proper pairs: (1, 466) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (192, 466, 867) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2217) [M::mem_pestat] mean and std.dev: (554.91, 489.98) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2892) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (211, 348, 1099) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2875) [M::mem_pestat] mean and std.dev: (616.97, 675.00) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3763) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 770132 reads in 219.265 CPU sec, 6.974 real sec sorting block 115, #reads = 1078098 mem = 536881451 peak = 1158770688 [M::mem_process_seqs] Processed 769710 reads in 257.381 CPU sec, 8.204 real sec sorting block 116, #reads = 1076837 mem = 536887822 peak = 1158770688 [M::process] read 769546 sequences (100000153 bp) in 2.642 CPU sec, 2.698 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 293452, 35, 67) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (149, 268, 998) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2696) [M::mem_pestat] mean and std.dev: (461.37, 501.54) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3545) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377) [M::mem_pestat] mean and std.dev: (159.07, 65.03) [M::mem_pestat] low and high boundaries for proper pairs: (1, 466) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (256, 437, 976) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2416) [M::mem_pestat] mean and std.dev: (618.09, 588.36) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3136) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (175, 250, 1029) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2737) [M::mem_pestat] mean and std.dev: (571.59, 629.60) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3591) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 775738 sequences (100000155 bp) in 1.840 CPU sec, 1.837 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 293905, 45, 65) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (173, 335, 747) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1895) [M::mem_pestat] mean and std.dev: (462.88, 415.71) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2469) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (111, 148, 200) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 378) [M::mem_pestat] mean and std.dev: (159.60, 65.26) [M::mem_pestat] low and high boundaries for proper pairs: (1, 467) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (214, 495, 1177) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3103) [M::mem_pestat] mean and std.dev: (645.60, 681.01) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4066) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (145, 303, 1106) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3028) [M::mem_pestat] mean and std.dev: (510.55, 635.04) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3989) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 770238 reads in 255.277 CPU sec, 8.137 real sec [M::mem_process_seqs] Processed 769352 reads in 292.576 CPU sec, 9.341 real sec sorting block 117, #reads = 1072525 mem = 536886131 peak = 1158770688 [M::process] read 785742 sequences (100000049 bp) in 2.578 CPU sec, 2.628 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 293596, 33, 63) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (165, 297, 968) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2574) [M::mem_pestat] mean and std.dev: (495.01, 526.25) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3377) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377) [M::mem_pestat] mean and std.dev: (159.13, 64.98) [M::mem_pestat] low and high boundaries for proper pairs: (1, 466) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (210, 611, 1681) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4623) [M::mem_pestat] mean and std.dev: (768.55, 744.23) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6094) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (159, 290, 769) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1989) [M::mem_pestat] mean and std.dev: (343.32, 332.39) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2599) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 781856 sequences (100000144 bp) in 1.870 CPU sec, 1.867 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 294611, 30, 75) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (227, 452, 917) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2297) [M::mem_pestat] mean and std.dev: (478.34, 337.59) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2987) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (108, 144, 194) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 366) [M::mem_pestat] mean and std.dev: (155.43, 62.54) [M::mem_pestat] low and high boundaries for proper pairs: (1, 452) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (94, 692, 2454) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7174) [M::mem_pestat] mean and std.dev: (1265.07, 1544.30) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9534) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (156, 207, 725) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1863) [M::mem_pestat] mean and std.dev: (396.48, 419.79) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2432) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 769546 reads in 264.583 CPU sec, 8.434 real sec sorting block 118, #reads = 1075715 mem = 536894505 peak = 1158770688 [M::mem_process_seqs] Processed 775738 reads in 318.185 CPU sec, 10.161 real sec sorting block 119, #reads = 1059364 mem = 536879867 peak = 1158770688 [M::process] read 780152 sequences (100000132 bp) in 3.190 CPU sec, 3.251 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 298209, 29, 47) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (190, 341, 997) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2611) [M::mem_pestat] mean and std.dev: (460.98, 421.04) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3418) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (106, 139, 185) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 343) [M::mem_pestat] mean and std.dev: (149.58, 57.99) [M::mem_pestat] low and high boundaries for proper pairs: (1, 422) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (143, 633, 982) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2660) [M::mem_pestat] mean and std.dev: (515.33, 534.25) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3499) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (195, 348, 817) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2061) [M::mem_pestat] mean and std.dev: (453.22, 410.00) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2683) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 778254 sequences (100000003 bp) in 2.438 CPU sec, 2.445 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 297602, 27, 51) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (152, 228, 936) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2504) [M::mem_pestat] mean and std.dev: (446.35, 456.35) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3288) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (107, 141, 189) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 353) [M::mem_pestat] mean and std.dev: (151.95, 59.93) [M::mem_pestat] low and high boundaries for proper pairs: (1, 435) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (246, 772, 2532) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7104) [M::mem_pestat] mean and std.dev: (1348.31, 1518.70) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9390) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (211, 382, 742) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1804) [M::mem_pestat] mean and std.dev: (524.62, 450.10) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2335) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 785742 reads in 336.555 CPU sec, 10.734 real sec [M::mem_process_seqs] Processed 781856 reads in 392.195 CPU sec, 12.521 real sec sorting block 120, #reads = 1065262 mem = 536882555 peak = 1158770688 [M::process] read 776580 sequences (100000126 bp) in 3.371 CPU sec, 3.438 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 297616, 26, 46) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (171, 333, 1117) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3009) [M::mem_pestat] mean and std.dev: (588.59, 596.99) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3955) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (108, 142, 191) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 357) [M::mem_pestat] mean and std.dev: (153.06, 60.77) [M::mem_pestat] low and high boundaries for proper pairs: (1, 440) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (322, 565, 2380) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6496) [M::mem_pestat] mean and std.dev: (984.17, 1115.79) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8554) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (159, 533, 1356) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3750) [M::mem_pestat] mean and std.dev: (721.60, 781.58) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4947) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 776314 sequences (100000106 bp) in 2.501 CPU sec, 2.502 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 297091, 33, 52) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (154, 403, 714) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1834) [M::mem_pestat] mean and std.dev: (390.34, 334.23) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2394) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (108, 143, 191) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 357) [M::mem_pestat] mean and std.dev: (153.82, 61.08) [M::mem_pestat] low and high boundaries for proper pairs: (1, 440) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (203, 460, 815) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2039) [M::mem_pestat] mean and std.dev: (489.60, 336.28) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2651) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (163, 236, 1023) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2743) [M::mem_pestat] mean and std.dev: (448.60, 480.33) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3603) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 780152 reads in 322.560 CPU sec, 10.271 real sec sorting block 121, #reads = 1069741 mem = 536883281 peak = 1158770688 [M::mem_process_seqs] Processed 778254 reads in 371.318 CPU sec, 11.844 real sec sorting block 122, #reads = 1074305 mem = 536879691 peak = 1158770688 [M::process] read 775350 sequences (100000024 bp) in 3.251 CPU sec, 3.305 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 296785, 22, 51) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (151, 268, 1061) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2881) [M::mem_pestat] mean and std.dev: (498.94, 554.42) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3791) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (108, 144, 194) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 366) [M::mem_pestat] mean and std.dev: (155.43, 62.63) [M::mem_pestat] low and high boundaries for proper pairs: (1, 452) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (677, 984, 1507) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3167) [M::mem_pestat] mean and std.dev: (911.60, 520.00) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3997) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (196, 365, 1016) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2656) [M::mem_pestat] mean and std.dev: (521.49, 578.76) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3476) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 774654 sequences (100000194 bp) in 2.490 CPU sec, 2.492 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 297410, 29, 59) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (170, 344, 1222) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3326) [M::mem_pestat] mean and std.dev: (553.04, 623.65) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4378) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (109, 144, 194) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 364) [M::mem_pestat] mean and std.dev: (155.30, 62.42) [M::mem_pestat] low and high boundaries for proper pairs: (1, 449) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (92, 773, 1313) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3755) [M::mem_pestat] mean and std.dev: (772.18, 737.09) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4976) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (172, 297, 791) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2029) [M::mem_pestat] mean and std.dev: (528.28, 489.72) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2648) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 776314 reads in 307.219 CPU sec, 9.781 real sec [M::mem_process_seqs] Processed 776580 reads in 352.872 CPU sec, 11.251 real sec sorting block 123, #reads = 1074869 mem = 536885412 peak = 1158770688 [M::process] read 774220 sequences (100000067 bp) in 2.962 CPU sec, 3.032 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 296052, 36, 61) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (204, 447, 1157) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3063) [M::mem_pestat] mean and std.dev: (570.05, 509.10) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4016) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (109, 145, 195) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 367) [M::mem_pestat] mean and std.dev: (156.34, 63.18) [M::mem_pestat] low and high boundaries for proper pairs: (1, 453) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (138, 570, 1102) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3030) [M::mem_pestat] mean and std.dev: (676.65, 669.60) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3994) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (161, 256, 740) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1898) [M::mem_pestat] mean and std.dev: (408.46, 379.50) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2477) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 772978 sequences (100000047 bp) in 1.880 CPU sec, 1.874 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 296030, 30, 74) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (179, 377, 1333) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3641) [M::mem_pestat] mean and std.dev: (623.72, 655.99) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4795) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (109, 145, 195) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 367) [M::mem_pestat] mean and std.dev: (155.97, 62.90) [M::mem_pestat] low and high boundaries for proper pairs: (1, 453) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (328, 590, 2714) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7486) [M::mem_pestat] mean and std.dev: (1665.93, 2070.53) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9948) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (194, 545, 1107) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2933) [M::mem_pestat] mean and std.dev: (661.41, 646.63) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3846) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 774654 reads in 299.450 CPU sec, 9.546 real sec sorting block 124, #reads = 1075633 mem = 536884249 peak = 1158770688 [M::mem_process_seqs] Processed 775350 reads in 342.858 CPU sec, 10.947 real sec sorting block 125, #reads = 1073957 mem = 536888869 peak = 1158770688 [M::process] read 772464 sequences (100000077 bp) in 3.194 CPU sec, 3.240 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 295045, 36, 61) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (171, 438, 1010) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2688) [M::mem_pestat] mean and std.dev: (650.96, 720.25) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3532) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (109, 146, 196) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 370) [M::mem_pestat] mean and std.dev: (157.18, 63.70) [M::mem_pestat] low and high boundaries for proper pairs: (1, 457) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (343, 753, 2554) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6976) [M::mem_pestat] mean and std.dev: (1624.56, 1899.38) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9222) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (194, 293, 1207) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3233) [M::mem_pestat] mean and std.dev: (614.84, 614.19) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4246) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 771216 sequences (100000147 bp) in 2.582 CPU sec, 2.585 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 295467, 33, 71) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (134, 204, 926) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2510) [M::mem_pestat] mean and std.dev: (516.09, 616.63) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3302) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (109, 145, 196) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 370) [M::mem_pestat] mean and std.dev: (156.69, 63.55) [M::mem_pestat] low and high boundaries for proper pairs: (1, 457) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (200, 564, 1165) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3095) [M::mem_pestat] mean and std.dev: (548.61, 516.86) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4060) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (208, 327, 1243) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3313) [M::mem_pestat] mean and std.dev: (665.68, 723.57) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4348) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 772978 reads in 280.582 CPU sec, 8.906 real sec [M::process] read 770862 sequences (100000112 bp) in 2.356 CPU sec, 2.368 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 295290, 35, 56) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (168, 261, 748) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1908) [M::mem_pestat] mean and std.dev: (357.72, 379.29) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2488) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 146, 197) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371) [M::mem_pestat] mean and std.dev: (157.48, 63.99) [M::mem_pestat] low and high boundaries for proper pairs: (1, 458) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (237, 407, 1241) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3249) [M::mem_pestat] mean and std.dev: (586.53, 666.84) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4253) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (187, 325, 992) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2602) [M::mem_pestat] mean and std.dev: (497.75, 508.57) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3407) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 772464 reads in 166.070 CPU sec, 5.314 real sec sorting block 126, #reads = 1077641 mem = 536876191 peak = 1158770688 [M::mem_process_seqs] Processed 774220 reads in 539.167 CPU sec, 17.206 real sec sorting block 127, #reads = 1078053 mem = 536885589 peak = 1158770688 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 294782, 37, 58) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (176, 422, 970) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2558) [M::mem_pestat] mean and std.dev: (527.05, 477.68) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3352) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 146, 197) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371) [M::mem_pestat] mean and std.dev: (158.08, 64.07) [M::mem_pestat] low and high boundaries for proper pairs: (1, 458) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (136, 316, 809) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2155) [M::mem_pestat] mean and std.dev: (353.93, 346.30) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2828) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (161, 284, 749) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1925) [M::mem_pestat] mean and std.dev: (461.88, 443.81) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2513) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 769392 sequences (100000077 bp) in 3.366 CPU sec, 3.491 real sec... [M::process] read 770052 sequences (100000112 bp) in 2.269 CPU sec, 2.271 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 294117, 48, 50) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (154, 267, 1114) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3034) [M::mem_pestat] mean and std.dev: (501.24, 564.27) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3994) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 147, 198) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374) [M::mem_pestat] mean and std.dev: (158.67, 64.55) [M::mem_pestat] low and high boundaries for proper pairs: (1, 462) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (245, 883, 4177) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12041) [M::mem_pestat] mean and std.dev: (1983.38, 2327.49) [M::mem_pestat] low and high boundaries for proper pairs: (1, 15973) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (191, 291, 493) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1097) [M::mem_pestat] mean and std.dev: (295.20, 164.35) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1399) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 771216 reads in 452.119 CPU sec, 14.431 real sec [M::mem_process_seqs] Processed 770862 reads in 213.244 CPU sec, 6.802 real sec sorting block 128, #reads = 1076403 mem = 536886081 peak = 1158770688 [M::process] read 769412 sequences (100000157 bp) in 3.324 CPU sec, 3.428 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 293418, 39, 76) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (185, 393, 922) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2396) [M::mem_pestat] mean and std.dev: (567.47, 582.27) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3133) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377) [M::mem_pestat] mean and std.dev: (159.05, 64.83) [M::mem_pestat] low and high boundaries for proper pairs: (1, 466) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (155, 369, 1068) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2894) [M::mem_pestat] mean and std.dev: (552.83, 570.55) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3807) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (234, 371, 909) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2259) [M::mem_pestat] mean and std.dev: (522.31, 428.58) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2934) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 769510 sequences (100000187 bp) in 2.510 CPU sec, 2.505 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 293022, 36, 57) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (207, 360, 907) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2307) [M::mem_pestat] mean and std.dev: (525.04, 472.72) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3007) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (111, 147, 199) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 375) [M::mem_pestat] mean and std.dev: (159.43, 64.92) [M::mem_pestat] low and high boundaries for proper pairs: (1, 463) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (117, 682, 1465) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4161) [M::mem_pestat] mean and std.dev: (750.27, 800.74) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5509) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (185, 281, 887) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2291) [M::mem_pestat] mean and std.dev: (379.52, 367.05) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2993) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 770052 reads in 287.865 CPU sec, 9.148 real sec sorting block 129, #reads = 1075323 mem = 536876567 peak = 1158770688 [M::mem_process_seqs] Processed 769392 reads in 327.774 CPU sec, 10.530 real sec sorting block 130, #reads = 1075846 mem = 536881998 peak = 1158770688 [M::process] read 768482 sequences (100000174 bp) in 3.089 CPU sec, 3.155 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 292788, 35, 61) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (143, 241, 448) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1058) [M::mem_pestat] mean and std.dev: (262.61, 173.06) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1363) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (111, 147, 200) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 378) [M::mem_pestat] mean and std.dev: (159.63, 65.26) [M::mem_pestat] low and high boundaries for proper pairs: (1, 467) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (306, 496, 1398) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3582) [M::mem_pestat] mean and std.dev: (691.75, 688.66) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4674) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (166, 274, 930) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2458) [M::mem_pestat] mean and std.dev: (479.20, 480.07) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3222) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 768974 sequences (100000208 bp) in 2.420 CPU sec, 2.423 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 293250, 30, 62) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (155, 232, 563) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1379) [M::mem_pestat] mean and std.dev: (306.84, 276.45) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1787) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (111, 147, 200) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 378) [M::mem_pestat] mean and std.dev: (159.58, 65.30) [M::mem_pestat] low and high boundaries for proper pairs: (1, 467) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (81, 649, 2714) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7980) [M::mem_pestat] mean and std.dev: (1890.80, 2412.69) [M::mem_pestat] low and high boundaries for proper pairs: (1, 11542) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (186, 303, 746) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1866) [M::mem_pestat] mean and std.dev: (493.03, 444.29) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2426) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 769412 reads in 282.607 CPU sec, 9.065 real sec [M::mem_process_seqs] Processed 769510 reads in 322.705 CPU sec, 10.368 real sec sorting block 131, #reads = 1075265 mem = 536880212 peak = 1158770688 [M::process] read 768072 sequences (100000278 bp) in 3.166 CPU sec, 3.215 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 293403, 31, 70) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (207, 308, 1043) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2715) [M::mem_pestat] mean and std.dev: (560.67, 534.06) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3551) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (111, 148, 200) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 378) [M::mem_pestat] mean and std.dev: (159.95, 65.42) [M::mem_pestat] low and high boundaries for proper pairs: (1, 467) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (426, 643, 1557) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3819) [M::mem_pestat] mean and std.dev: (598.08, 428.78) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4950) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (155, 254, 725) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1865) [M::mem_pestat] mean and std.dev: (399.02, 372.24) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2435) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 767964 sequences (100000060 bp) in 2.380 CPU sec, 2.378 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 293106, 39, 56) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (208, 348, 663) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1573) [M::mem_pestat] mean and std.dev: (366.17, 269.93) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2028) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (111, 148, 200) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 378) [M::mem_pestat] mean and std.dev: (159.88, 65.43) [M::mem_pestat] low and high boundaries for proper pairs: (1, 467) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (227, 577, 1022) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2612) [M::mem_pestat] mean and std.dev: (569.44, 460.64) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3407) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (209, 348, 800) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1982) [M::mem_pestat] mean and std.dev: (481.42, 432.29) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2573) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 768482 reads in 273.373 CPU sec, 8.690 real sec sorting block 132, #reads = 1076632 mem = 536879802 peak = 1158770688 [M::mem_process_seqs] Processed 768974 reads in 313.514 CPU sec, 9.991 real sec [M::process] read 557062 sequences (72327087 bp) in 1.913 CPU sec, 1.952 real sec... sorting block 133, #reads = 1076708 mem = 536877247 peak = 1158770688 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 292792, 28, 53) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (153, 298, 1195) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3279) [M::mem_pestat] mean and std.dev: (509.73, 541.41) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4321) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381) [M::mem_pestat] mean and std.dev: (160.39, 65.78) [M::mem_pestat] low and high boundaries for proper pairs: (1, 471) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (127, 443, 868) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2350) [M::mem_pestat] mean and std.dev: (557.04, 507.93) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3091) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (172, 286, 618) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1510) [M::mem_pestat] mean and std.dev: (347.42, 310.44) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1956) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 293381, 35, 59) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (159, 441, 906) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2400) [M::mem_pestat] mean and std.dev: (497.76, 455.19) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3147) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381) [M::mem_pestat] mean and std.dev: (160.51, 65.89) [M::mem_pestat] low and high boundaries for proper pairs: (1, 471) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (234, 559, 1295) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3417) [M::mem_pestat] mean and std.dev: (673.50, 690.45) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4478) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (218, 524, 1138) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2978) [M::mem_pestat] mean and std.dev: (743.79, 725.36) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3898) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 768072 reads in 264.123 CPU sec, 8.491 real sec [M::mem_process_seqs] Processed 767964 reads in 309.506 CPU sec, 9.966 real sec sorting block 134, #reads = 1077986 mem = 536881420 peak = 1158770688 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 212157, 35, 42) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (165, 354, 1122) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3036) [M::mem_pestat] mean and std.dev: (557.36, 552.40) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3993) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377) [M::mem_pestat] mean and std.dev: (159.13, 65.18) [M::mem_pestat] low and high boundaries for proper pairs: (1, 466) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (391, 695, 1364) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3310) [M::mem_pestat] mean and std.dev: (729.06, 579.31) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4283) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (160, 348, 1092) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2956) [M::mem_pestat] mean and std.dev: (504.53, 584.82) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3888) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 557062 reads in 121.281 CPU sec, 3.980 real sec os version: Linux 6.12.88 cpu vendor: GenuineIntel signature: 000c06f2 features: bfebfbff 7ffefbff extended: f3bfb7ef fb417ffe amd bits: 2c100800 00000121 brand: INTEL(R) XEON(R) PLATINUM 8559C threads: 31 algo: bwa-mem license: sentieon:klib=31 reads: 144942202 overall: 72305745920 mem 30579.840 user 413.351 sys 1007.577 real [main] Version: 0.7.17-r1188 [main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1136_81F-T1-TDNA-1_A23MHWWLT4_1.L005\tPU:L005\tSM:1136_81F-T1-TDNA-1_A23MHWWLT4_1\tLB:1136_81F-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1136_81F-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1136_81F-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz [main] Real time: 1007.616 sec; CPU: 30993.194 sec sorting block 135, #reads = 1050956 mem = 525496288 peak = 1158770688 uniq header count 1 merging 136 blocks sw version: sentieon-genomics-202308.03 os version: Linux 6.12.88 cpu vendor: GenuineIntel signature: 000c06f2 features: bfebfbff 7ffefbff extended: f3bfb7ef fb417ffe amd bits: 2c100800 00000121 brand: INTEL(R) XEON(R) PLATINUM 8559C threads: 31 max 192 algo: util-sort license: sentieon:util=1 output file size: 8947572720 output reads: 146949762 bam_mem_sort: 136 calls 83.986 user 1.723 sys 85.963 real bam_write: 136 calls 72.721 user 3.654 sys 85.039 real execute: 1 calls 48.057 user 2.082 sys 1072.397 real merge_files: 1 calls 48.057 user 2.025 sys 63.739 real parse_chunk: 2176 calls 129.136 user 30.317 sys 164.463 real read_chunk: 5945 calls 72.232 user 38.241 sys 977.350 real sort_block: 1 calls 48.042 user 37.557 sys 945.722 real write_chunk: 3767 calls 47.544 user 1.660 sys 62.492 real overall: 4521857024 mem 2515.980 user 103.162 sys 1072.418 real ls: cannot access '*.cram': No such file or directory