.command.err - Workdir - DAQ:SENTIEON_BWAMEM (1029_HTI-T1-TDNA-1_A23MHWWLT4_1;L002;0001)

File Info

Filename: .command.err
Full Path: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/50/657e5d0267bfc44ca9dfe85dc24488/.command.err
Size: 450.9 KB
Task: DAQ:SENTIEON_BWAMEM (1029_HTI-T1-TDNA-1_A23MHWWLT4_1;L002;0001)
Attempt
Content

This software is licensed to bgold@natera.com by Sentieon Inc.
cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1029_HTI-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 1790.483 CPU sec, 62.347 real sec
[M::process] read 702478 sequences (100000131 bp) in 0.978 CPU sec, 0.984 real sec...
[M::process] read 700920 sequences (100000071 bp) in 1.460 CPU sec, 1.462 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 282919, 30, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 262, 1026)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2704)
[M::mem_pestat] mean and std.dev: (529.32, 615.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3543)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 221, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 648)
[M::mem_pestat] mean and std.dev: (244.28, 117.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 813)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (99, 363, 584)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1554)
[M::mem_pestat] mean and std.dev: (325.00, 270.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2039)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 303, 524)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1210)
[M::mem_pestat] mean and std.dev: (334.78, 207.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1553)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700688 sequences (100000057 bp) in 1.530 CPU sec, 1.533 real sec...
[M::process] read 699784 sequences (100000034 bp) in 1.509 CPU sec, 1.516 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 282613, 17, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 319, 1281)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3503)
[M::mem_pestat] mean and std.dev: (661.60, 708.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4614)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 224, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 658)
[M::mem_pestat] mean and std.dev: (247.23, 118.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 826)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (441, 743, 1864)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4710)
[M::mem_pestat] mean and std.dev: (751.87, 626.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6133)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 800, 1399)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3703)
[M::mem_pestat] mean and std.dev: (946.62, 888.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4855)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702478 reads in 189.225 CPU sec, 5.969 real sec
[M::process] read 699406 sequences (100000284 bp) in 1.879 CPU sec, 1.888 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 282933, 35, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 288, 1268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3512)
[M::mem_pestat] mean and std.dev: (670.15, 749.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4634)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 227, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 665)
[M::mem_pestat] mean and std.dev: (249.45, 120.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 835)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (440, 513, 916)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1868)
[M::mem_pestat] mean and std.dev: (526.52, 321.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2344)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 371, 523)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1151)
[M::mem_pestat] mean and std.dev: (358.10, 228.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1465)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700688 reads in 107.913 CPU sec, 3.436 real sec
sorting block 0, #reads = 1073324 mem = 536877704 peak = 601968640
[M::mem_process_seqs] Processed 700920 reads in 263.268 CPU sec, 8.431 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 282239, 31, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 281, 1094)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2834)
[M::mem_pestat] mean and std.dev: (663.88, 680.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3704)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 228, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 669)
[M::mem_pestat] mean and std.dev: (251.13, 120.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 840)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (345, 760, 1286)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3168)
[M::mem_pestat] mean and std.dev: (893.45, 669.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4109)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 445, 976)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2558)
[M::mem_pestat] mean and std.dev: (567.24, 521.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3349)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699222 sequences (100000091 bp) in 2.140 CPU sec, 2.362 real sec...
[M::process] read 698874 sequences (100000031 bp) in 1.631 CPU sec, 1.644 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 281992, 33, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 290, 950)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2502)
[M::mem_pestat] mean and std.dev: (547.08, 602.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3278)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 229, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 673)
[M::mem_pestat] mean and std.dev: (252.72, 122.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 845)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (261, 421, 1493)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3957)
[M::mem_pestat] mean and std.dev: (885.33, 818.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5189)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 352, 719)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1725)
[M::mem_pestat] mean and std.dev: (397.46, 295.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2228)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699784 reads in 214.853 CPU sec, 6.895 real sec
sorting block 1, #reads = 1073709 mem = 536887937 peak = 835969024
[M::mem_process_seqs] Processed 699406 reads in 129.590 CPU sec, 4.155 real sec
sorting block 2, #reads = 1073065 mem = 536881290 peak = 947933184
[M::process] read 698486 sequences (100000196 bp) in 2.162 CPU sec, 2.431 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 282630, 20, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 552, 1741)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4783)
[M::mem_pestat] mean and std.dev: (793.93, 970.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6304)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 230, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (253.57, 122.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 853)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (83, 432, 1741)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5057)
[M::mem_pestat] mean and std.dev: (1062.89, 1552.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7273)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (343, 442, 1120)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2674)
[M::mem_pestat] mean and std.dev: (689.19, 496.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3451)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698216 sequences (100000075 bp) in 1.775 CPU sec, 1.840 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 282674, 36, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 268, 790)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2084)
[M::mem_pestat] mean and std.dev: (389.61, 387.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2731)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 231, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (254.40, 122.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (79, 300, 941)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2665)
[M::mem_pestat] mean and std.dev: (536.85, 608.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3527)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 285, 984)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2526)
[M::mem_pestat] mean and std.dev: (572.00, 583.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3297)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699222 reads in 195.165 CPU sec, 6.286 real sec
[M::mem_process_seqs] Processed 698874 reads in 133.902 CPU sec, 4.336 real sec
sorting block 3, #reads = 1074557 mem = 536879197 peak = 947933184
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 281922, 18, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 383, 795)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1971)
[M::mem_pestat] mean and std.dev: (434.41, 357.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2559)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 232, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684)
[M::mem_pestat] mean and std.dev: (256.14, 124.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 859)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (33, 446, 681)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1977)
[M::mem_pestat] mean and std.dev: (533.17, 525.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2634)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 247, 995)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2599)
[M::mem_pestat] mean and std.dev: (572.86, 588.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3401)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698062 sequences (100000289 bp) in 2.027 CPU sec, 2.361 real sec...
[M::process] read 697726 sequences (100000072 bp) in 1.791 CPU sec, 1.792 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 282316, 21, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 391, 1880)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5112)
[M::mem_pestat] mean and std.dev: (1013.67, 1189.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6728)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 232, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684)
[M::mem_pestat] mean and std.dev: (255.93, 124.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 859)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (100, 499, 5948)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 17644)
[M::mem_pestat] mean and std.dev: (2257.14, 2672.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 23492)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 310, 1064)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2798)
[M::mem_pestat] mean and std.dev: (537.76, 558.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3665)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698486 reads in 200.048 CPU sec, 6.537 real sec
[M::mem_process_seqs] Processed 698216 reads in 136.219 CPU sec, 4.405 real sec
sorting block 4, #reads = 1074902 mem = 536877770 peak = 947933184
[M::process] read 697288 sequences (100000108 bp) in 2.090 CPU sec, 2.301 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 282471, 14, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (396, 960, 1908)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4932)
[M::mem_pestat] mean and std.dev: (948.76, 759.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6444)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 234, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (257.43, 124.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 867)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (298, 553, 1312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3340)
[M::mem_pestat] mean and std.dev: (672.08, 496.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4354)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 285, 879)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2299)
[M::mem_pestat] mean and std.dev: (509.92, 462.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3009)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697192 sequences (100000274 bp) in 1.820 CPU sec, 1.823 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 281648, 18, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 414, 905)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2315)
[M::mem_pestat] mean and std.dev: (482.41, 355.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3020)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 234, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (257.90, 125.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (965, 1231, 1670)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3080)
[M::mem_pestat] mean and std.dev: (1080.33, 643.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3785)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 427, 1114)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2880)
[M::mem_pestat] mean and std.dev: (653.12, 574.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3763)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698062 reads in 203.971 CPU sec, 6.636 real sec
sorting block 5, #reads = 1073114 mem = 536880116 peak = 947933184
[M::mem_process_seqs] Processed 697726 reads in 136.162 CPU sec, 4.387 real sec
sorting block 6, #reads = 1072523 mem = 536878923 peak = 947933184
[M::process] read 697070 sequences (100000182 bp) in 2.208 CPU sec, 2.348 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 282615, 32, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 439, 1452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3910)
[M::mem_pestat] mean and std.dev: (890.98, 912.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5139)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 235, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 694)
[M::mem_pestat] mean and std.dev: (259.13, 125.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 872)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (321, 893, 2945)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8193)
[M::mem_pestat] mean and std.dev: (1587.13, 1553.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10817)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 477, 1180)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3180)
[M::mem_pestat] mean and std.dev: (576.00, 573.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4180)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696700 sequences (100000080 bp) in 1.851 CPU sec, 1.859 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 281905, 18, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 515, 1216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3284)
[M::mem_pestat] mean and std.dev: (654.88, 532.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4318)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 235, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 694)
[M::mem_pestat] mean and std.dev: (259.07, 125.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 872)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (474, 1054, 1241)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2775)
[M::mem_pestat] mean and std.dev: (869.31, 556.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3542)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 339, 1104)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2856)
[M::mem_pestat] mean and std.dev: (564.12, 458.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3732)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697288 reads in 203.269 CPU sec, 6.622 real sec
[M::mem_process_seqs] Processed 697192 reads in 136.779 CPU sec, 4.442 real sec
sorting block 7, #reads = 1074671 mem = 536878963 peak = 947933184
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 281659, 16, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 317, 840)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2078)
[M::mem_pestat] mean and std.dev: (421.47, 367.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2697)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 235, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (259.20, 125.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 869)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (290, 403, 593)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1199)
[M::mem_pestat] mean and std.dev: (323.31, 155.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1502)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (294, 517, 1359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3489)
[M::mem_pestat] mean and std.dev: (916.43, 867.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4554)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696740 sequences (100000294 bp) in 2.205 CPU sec, 2.419 real sec...
[M::process] read 697174 sequences (100000228 bp) in 2.015 CPU sec, 2.021 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 281213, 42, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 432, 1465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3965)
[M::mem_pestat] mean and std.dev: (881.87, 861.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5215)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 236, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (259.39, 125.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 869)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (276, 1048, 2435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6753)
[M::mem_pestat] mean and std.dev: (1351.90, 1189.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8912)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 335, 1052)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2662)
[M::mem_pestat] mean and std.dev: (691.30, 700.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3492)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697070 reads in 201.849 CPU sec, 6.608 real sec
[M::mem_process_seqs] Processed 696700 reads in 133.681 CPU sec, 4.304 real sec
sorting block 8, #reads = 1073788 mem = 536881980 peak = 947933184
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 280868, 22, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 369, 562)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1206)
[M::mem_pestat] mean and std.dev: (377.79, 206.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1528)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 235, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (258.61, 124.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 865)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (269, 537, 1125)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2837)
[M::mem_pestat] mean and std.dev: (822.09, 744.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3800)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 347, 890)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2290)
[M::mem_pestat] mean and std.dev: (596.04, 587.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2990)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697480 sequences (100000154 bp) in 2.324 CPU sec, 2.723 real sec...
[M::process] read 697190 sequences (100000203 bp) in 1.724 CPU sec, 1.737 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 281272, 18, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 437, 1204)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3116)
[M::mem_pestat] mean and std.dev: (590.86, 467.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4072)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 234, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (257.31, 124.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 860)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 532, 739)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1819)
[M::mem_pestat] mean and std.dev: (553.35, 449.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2359)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 428, 966)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2492)
[M::mem_pestat] mean and std.dev: (633.87, 543.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3255)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696740 reads in 194.148 CPU sec, 6.321 real sec
sorting block 9, #reads = 1072055 mem = 536886969 peak = 947933184
[M::mem_process_seqs] Processed 697174 reads in 132.947 CPU sec, 4.289 real sec
sorting block 10, #reads = 1072688 mem = 536878924 peak = 947933184
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 281296, 34, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 332, 921)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2277)
[M::mem_pestat] mean and std.dev: (500.16, 371.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2955)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 233, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (256.51, 123.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 856)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (291, 777, 1670)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4428)
[M::mem_pestat] mean and std.dev: (862.44, 682.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5807)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 440, 724)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1724)
[M::mem_pestat] mean and std.dev: (529.90, 374.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2224)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697380 sequences (100000091 bp) in 2.367 CPU sec, 2.495 real sec...
[M::process] read 697252 sequences (100000071 bp) in 1.853 CPU sec, 1.858 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 282204, 20, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 307, 779)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1961)
[M::mem_pestat] mean and std.dev: (463.42, 410.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2552)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 233, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (256.90, 123.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 860)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (108, 1201, 1925)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5559)
[M::mem_pestat] mean and std.dev: (1154.17, 1329.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7376)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 311, 654)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1548)
[M::mem_pestat] mean and std.dev: (360.42, 246.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1995)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697480 reads in 192.508 CPU sec, 6.203 real sec
[M::mem_process_seqs] Processed 697190 reads in 132.029 CPU sec, 4.243 real sec
sorting block 11, #reads = 1072159 mem = 536879364 peak = 947933184
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 281477, 27, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 369, 632)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1412)
[M::mem_pestat] mean and std.dev: (405.18, 229.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1802)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 233, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (256.95, 123.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 860)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (450, 1142, 1475)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3525)
[M::mem_pestat] mean and std.dev: (951.39, 719.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4550)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 272, 406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 876)
[M::mem_pestat] mean and std.dev: (255.17, 109.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1111)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696692 sequences (100000289 bp) in 2.524 CPU sec, 2.698 real sec...
[M::process] read 696632 sequences (100000079 bp) in 1.862 CPU sec, 1.863 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 281980, 35, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 292, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 573)
[M::mem_pestat] mean and std.dev: (249.19, 87.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 699)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 234, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (257.08, 123.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 860)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (378, 824, 1359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3321)
[M::mem_pestat] mean and std.dev: (858.91, 591.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4302)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 366, 915)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2311)
[M::mem_pestat] mean and std.dev: (602.97, 522.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3009)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697380 reads in 196.372 CPU sec, 6.326 real sec
[M::mem_process_seqs] Processed 697252 reads in 130.976 CPU sec, 4.229 real sec
sorting block 12, #reads = 1072972 mem = 536877524 peak = 947933184
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 281248, 14, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 333, 1105)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2889)
[M::mem_pestat] mean and std.dev: (573.09, 595.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3781)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 235, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 686)
[M::mem_pestat] mean and std.dev: (258.04, 123.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 861)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (285, 696, 854)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1992)
[M::mem_pestat] mean and std.dev: (617.15, 366.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2561)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (264, 473, 1071)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2685)
[M::mem_pestat] mean and std.dev: (563.56, 469.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3492)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696070 sequences (100000069 bp) in 2.333 CPU sec, 2.552 real sec...
[M::process] read 695950 sequences (100000141 bp) in 1.859 CPU sec, 1.868 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 281515, 33, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 472, 1392)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3744)
[M::mem_pestat] mean and std.dev: (585.90, 559.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4920)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 235, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (258.62, 124.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 865)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (356, 816, 1635)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4193)
[M::mem_pestat] mean and std.dev: (1032.53, 826.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5472)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 328, 820)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1984)
[M::mem_pestat] mean and std.dev: (430.07, 343.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2566)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696692 reads in 191.561 CPU sec, 6.150 real sec
sorting block 13, #reads = 1072053 mem = 536879914 peak = 947933184
[M::mem_process_seqs] Processed 696632 reads in 129.985 CPU sec, 4.139 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 281162, 23, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 236, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 963)
[M::mem_pestat] mean and std.dev: (267.12, 142.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1223)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 236, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (259.36, 124.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 869)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 872, 1099)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2877)
[M::mem_pestat] mean and std.dev: (499.78, 395.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3766)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 299, 879)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2183)
[M::mem_pestat] mean and std.dev: (501.98, 497.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2835)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 14, #reads = 1072787 mem = 536879462 peak = 947933184
[M::process] read 694904 sequences (100000242 bp) in 2.460 CPU sec, 2.775 real sec...
[M::process] read 695720 sequences (100000219 bp) in 1.829 CPU sec, 1.842 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281476, 12, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 303, 1030)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2732)
[M::mem_pestat] mean and std.dev: (435.97, 455.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3583)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 237, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (260.02, 124.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (517, 624, 1468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3370)
[M::mem_pestat] mean and std.dev: (622.10, 502.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4321)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (285, 390, 1010)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2460)
[M::mem_pestat] mean and std.dev: (540.38, 420.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3185)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696070 reads in 193.605 CPU sec, 6.222 real sec
[M::mem_process_seqs] Processed 695950 reads in 131.442 CPU sec, 4.227 real sec
sorting block 15, #reads = 1072590 mem = 536878990 peak = 947933184
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 281161, 18, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 447, 1667)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4585)
[M::mem_pestat] mean and std.dev: (952.47, 994.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6044)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 241, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 704)
[M::mem_pestat] mean and std.dev: (263.92, 126.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 884)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 833, 1833)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5179)
[M::mem_pestat] mean and std.dev: (1048.72, 961.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6852)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 334, 2097)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5819)
[M::mem_pestat] mean and std.dev: (905.51, 1127.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7680)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695346 sequences (100000233 bp) in 2.484 CPU sec, 2.793 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281075, 23, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 382, 928)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2368)
[M::mem_pestat] mean and std.dev: (595.44, 606.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3088)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 238, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (260.25, 124.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 385, 1187)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3159)
[M::mem_pestat] mean and std.dev: (774.86, 853.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4189)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 229, 601)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1499)
[M::mem_pestat] mean and std.dev: (268.56, 222.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1948)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694824 sequences (100000113 bp) in 2.078 CPU sec, 2.103 real sec...
[M::mem_process_seqs] Processed 694904 reads in 190.833 CPU sec, 6.111 real sec
[M::mem_process_seqs] Processed 695720 reads in 128.970 CPU sec, 4.128 real sec
sorting block 16, #reads = 1072589 mem = 536880423 peak = 947933184
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 280569, 36, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (326, 810, 1404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3560)
[M::mem_pestat] mean and std.dev: (821.75, 655.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4638)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 239, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 694)
[M::mem_pestat] mean and std.dev: (260.96, 124.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (486, 907, 2511)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6561)
[M::mem_pestat] mean and std.dev: (1254.71, 1115.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8586)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 364, 933)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2379)
[M::mem_pestat] mean and std.dev: (525.79, 456.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3102)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694910 sequences (100000034 bp) in 2.362 CPU sec, 2.687 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 281068, 26, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 442, 836)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2132)
[M::mem_pestat] mean and std.dev: (506.32, 427.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2780)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 239, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (261.02, 123.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 923, 1762)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4946)
[M::mem_pestat] mean and std.dev: (1028.85, 979.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6538)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 291, 735)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1807)
[M::mem_pestat] mean and std.dev: (403.21, 304.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2343)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694974 sequences (100000114 bp) in 1.963 CPU sec, 1.966 real sec...
[M::mem_process_seqs] Processed 695346 reads in 192.478 CPU sec, 6.411 real sec
[M::mem_process_seqs] Processed 694824 reads in 128.476 CPU sec, 4.098 real sec
sorting block 17, #reads = 1072344 mem = 536878324 peak = 947933184
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281084, 27, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 302, 949)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2525)
[M::mem_pestat] mean and std.dev: (506.43, 510.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3313)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 240, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (261.34, 123.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 795, 1241)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3435)
[M::mem_pestat] mean and std.dev: (732.11, 515.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4532)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 390, 499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 997)
[M::mem_pestat] mean and std.dev: (379.64, 185.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1246)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 18, #reads = 1071965 mem = 536880067 peak = 947933184
[M::process] read 694498 sequences (100000078 bp) in 2.507 CPU sec, 2.755 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 281051, 26, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 357, 1001)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2681)
[M::mem_pestat] mean and std.dev: (473.77, 475.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3521)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 241, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (262.75, 125.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 876)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 516, 2386)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6630)
[M::mem_pestat] mean and std.dev: (1080.72, 1194.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8752)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 401, 1738)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4750)
[M::mem_pestat] mean and std.dev: (791.61, 847.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6256)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694456 sequences (100000107 bp) in 1.868 CPU sec, 1.947 real sec...
[M::mem_process_seqs] Processed 694910 reads in 186.715 CPU sec, 6.007 real sec
[M::mem_process_seqs] Processed 694974 reads in 128.139 CPU sec, 4.112 real sec
sorting block 19, #reads = 1072354 mem = 536882566 peak = 947933184
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 281246, 34, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 393, 2442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6914)
[M::mem_pestat] mean and std.dev: (1231.89, 1412.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9150)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 241, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 704)
[M::mem_pestat] mean and std.dev: (263.64, 125.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 884)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (35, 238, 618)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1784)
[M::mem_pestat] mean and std.dev: (351.03, 365.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2367)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 308, 1030)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2662)
[M::mem_pestat] mean and std.dev: (496.72, 511.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3478)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694194 sequences (100000249 bp) in 2.437 CPU sec, 2.638 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 281276, 28, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 271, 1138)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3102)
[M::mem_pestat] mean and std.dev: (566.30, 578.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4084)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 243, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 708)
[M::mem_pestat] mean and std.dev: (265.31, 127.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 889)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 531, 825)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2047)
[M::mem_pestat] mean and std.dev: (446.17, 357.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2658)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (293, 336, 817)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1865)
[M::mem_pestat] mean and std.dev: (548.37, 463.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2403)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694992 sequences (100000241 bp) in 1.941 CPU sec, 1.951 real sec...
[M::mem_process_seqs] Processed 694498 reads in 185.797 CPU sec, 5.953 real sec
[M::mem_process_seqs] Processed 694456 reads in 127.860 CPU sec, 4.095 real sec
sorting block 20, #reads = 1073035 mem = 536879956 peak = 947933184
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 280907, 24, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 369, 959)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2519)
[M::mem_pestat] mean and std.dev: (560.18, 538.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3299)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 243, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 708)
[M::mem_pestat] mean and std.dev: (265.50, 127.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 889)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (125, 346, 2074)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5972)
[M::mem_pestat] mean and std.dev: (1352.04, 1718.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8226)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (316, 481, 966)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2266)
[M::mem_pestat] mean and std.dev: (654.62, 516.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2916)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701786 sequences (100000014 bp) in 2.443 CPU sec, 2.743 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 280686, 34, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 304, 1035)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2659)
[M::mem_pestat] mean and std.dev: (640.60, 639.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3471)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 241, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 704)
[M::mem_pestat] mean and std.dev: (263.52, 126.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 884)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (282, 655, 1421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3699)
[M::mem_pestat] mean and std.dev: (877.19, 723.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4838)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 301, 785)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1899)
[M::mem_pestat] mean and std.dev: (461.52, 394.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2456)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700540 sequences (100000000 bp) in 1.872 CPU sec, 1.881 real sec...
[M::mem_process_seqs] Processed 694194 reads in 196.387 CPU sec, 6.550 real sec
[M::mem_process_seqs] Processed 694992 reads in 133.831 CPU sec, 4.277 real sec
sorting block 21, #reads = 1071680 mem = 536881485 peak = 947933184
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 283163, 27, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 282, 708)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1734)
[M::mem_pestat] mean and std.dev: (424.34, 365.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2247)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 223, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 660)
[M::mem_pestat] mean and std.dev: (247.07, 119.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 829)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (84, 159, 2584)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7584)
[M::mem_pestat] mean and std.dev: (849.04, 1095.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10084)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 324, 993)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2637)
[M::mem_pestat] mean and std.dev: (540.15, 582.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3459)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700182 sequences (100000208 bp) in 2.426 CPU sec, 2.698 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 282607, 24, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 311, 1661)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4667)
[M::mem_pestat] mean and std.dev: (867.96, 1143.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6170)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 225, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (249.47, 120.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 839)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (327, 1250, 1548)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3990)
[M::mem_pestat] mean and std.dev: (1031.29, 781.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5211)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 444, 1230)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3182)
[M::mem_pestat] mean and std.dev: (768.27, 677.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4158)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699672 sequences (100000147 bp) in 1.843 CPU sec, 1.845 real sec...
[M::mem_process_seqs] Processed 701786 reads in 190.973 CPU sec, 6.145 real sec
sorting block 22, #reads = 1070172 mem = 536881726 peak = 947933184
[M::mem_process_seqs] Processed 700540 reads in 129.704 CPU sec, 4.145 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 282665, 31, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 616, 1114)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2884)
[M::mem_pestat] mean and std.dev: (672.62, 485.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3769)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 227, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 672)
[M::mem_pestat] mean and std.dev: (251.24, 121.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 844)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (469, 783, 1516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3610)
[M::mem_pestat] mean and std.dev: (1082.03, 970.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4965)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 324, 576)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1284)
[M::mem_pestat] mean and std.dev: (400.77, 277.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1638)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 23, #reads = 1075331 mem = 536880748 peak = 947933184
[M::process] read 699606 sequences (100000075 bp) in 2.205 CPU sec, 2.528 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 282620, 28, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 266, 853)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2125)
[M::mem_pestat] mean and std.dev: (324.76, 229.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2761)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 229, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 678)
[M::mem_pestat] mean and std.dev: (253.10, 123.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 852)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 616, 1075)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2911)
[M::mem_pestat] mean and std.dev: (598.68, 539.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3829)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 604, 992)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2464)
[M::mem_pestat] mean and std.dev: (586.83, 423.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3200)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698932 sequences (100000234 bp) in 1.970 CPU sec, 2.042 real sec...
[M::mem_process_seqs] Processed 700182 reads in 188.470 CPU sec, 6.083 real sec
[M::mem_process_seqs] Processed 699672 reads in 128.250 CPU sec, 4.114 real sec
sorting block 24, #reads = 1076303 mem = 536879927 peak = 947933184
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 282724, 20, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (252, 459, 1856)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5064)
[M::mem_pestat] mean and std.dev: (779.26, 889.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6668)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 230, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (253.81, 123.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 853)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 490, 1188)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3082)
[M::mem_pestat] mean and std.dev: (622.78, 435.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4029)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (387, 589, 1657)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4197)
[M::mem_pestat] mean and std.dev: (939.11, 906.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5467)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698916 sequences (100000076 bp) in 2.350 CPU sec, 2.788 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 281771, 20, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 533, 952)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2452)
[M::mem_pestat] mean and std.dev: (557.20, 545.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3202)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 231, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (255.29, 124.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (88, 281, 611)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1657)
[M::mem_pestat] mean and std.dev: (318.11, 295.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2180)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 303, 875)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2197)
[M::mem_pestat] mean and std.dev: (461.08, 359.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2858)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699606 reads in 187.889 CPU sec, 6.080 real sec
[M::process] read 698138 sequences (100000086 bp) in 2.004 CPU sec, 2.140 real sec...
[M::mem_process_seqs] Processed 698932 reads in 129.691 CPU sec, 4.165 real sec
sorting block 25, #reads = 1076786 mem = 536880726 peak = 947933184
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 282273, 19, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 218, 421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 997)
[M::mem_pestat] mean and std.dev: (250.59, 214.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1285)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 232, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (255.88, 124.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (376, 750, 1991)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5221)
[M::mem_pestat] mean and std.dev: (1169.95, 1054.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6836)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 367, 1665)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4553)
[M::mem_pestat] mean and std.dev: (742.86, 738.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5997)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698240 sequences (100000035 bp) in 2.596 CPU sec, 3.036 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281877, 24, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 390, 1017)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2621)
[M::mem_pestat] mean and std.dev: (594.25, 584.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3423)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 232, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (256.55, 124.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (522, 941, 1294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2838)
[M::mem_pestat] mean and std.dev: (798.00, 488.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3610)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (295, 360, 1308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3334)
[M::mem_pestat] mean and std.dev: (550.23, 463.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4347)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697788 sequences (100000123 bp) in 1.856 CPU sec, 1.868 real sec...
[M::mem_process_seqs] Processed 698916 reads in 189.534 CPU sec, 6.093 real sec
sorting block 26, #reads = 1075213 mem = 536879467 peak = 947933184
[M::mem_process_seqs] Processed 698138 reads in 129.919 CPU sec, 4.155 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 281926, 28, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 347, 745)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1753)
[M::mem_pestat] mean and std.dev: (489.44, 369.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2257)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 233, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (257.58, 125.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 427, 1205)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3125)
[M::mem_pestat] mean and std.dev: (606.65, 527.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4085)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 320, 605)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1375)
[M::mem_pestat] mean and std.dev: (352.72, 234.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1760)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 27, #reads = 1074072 mem = 536889057 peak = 947933184
[M::process] read 697400 sequences (100000019 bp) in 2.615 CPU sec, 2.928 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281961, 36, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 383, 589)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1297)
[M::mem_pestat] mean and std.dev: (394.42, 241.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1651)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 234, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (258.23, 125.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (49, 962, 1669)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4909)
[M::mem_pestat] mean and std.dev: (1085.58, 1120.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6529)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 385, 1362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3686)
[M::mem_pestat] mean and std.dev: (772.14, 699.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4848)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697644 sequences (100000208 bp) in 1.851 CPU sec, 1.886 real sec...
[M::mem_process_seqs] Processed 698240 reads in 191.884 CPU sec, 6.200 real sec
[M::mem_process_seqs] Processed 697788 reads in 130.432 CPU sec, 4.192 real sec
sorting block 28, #reads = 1075250 mem = 536878843 peak = 947933184
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 281676, 32, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (290, 491, 1196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3008)
[M::mem_pestat] mean and std.dev: (675.81, 480.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3914)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 235, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697)
[M::mem_pestat] mean and std.dev: (259.49, 126.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 876)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 529, 1692)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4690)
[M::mem_pestat] mean and std.dev: (1028.87, 1347.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6421)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 356, 697)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1709)
[M::mem_pestat] mean and std.dev: (380.71, 280.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2215)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696962 sequences (100000299 bp) in 2.623 CPU sec, 2.852 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 282042, 24, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 369, 1258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3326)
[M::mem_pestat] mean and std.dev: (638.97, 651.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4360)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 235, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 694)
[M::mem_pestat] mean and std.dev: (258.91, 126.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 872)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 563, 1193)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3127)
[M::mem_pestat] mean and std.dev: (684.68, 675.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4094)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (268, 329, 1195)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3049)
[M::mem_pestat] mean and std.dev: (598.11, 555.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3976)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697066 sequences (100000204 bp) in 1.766 CPU sec, 1.774 real sec...
[M::mem_process_seqs] Processed 697400 reads in 191.124 CPU sec, 6.150 real sec
[M::mem_process_seqs] Processed 697644 reads in 129.838 CPU sec, 4.180 real sec
sorting block 29, #reads = 1073445 mem = 536878980 peak = 947933184
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 281678, 24, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 429, 1008)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2594)
[M::mem_pestat] mean and std.dev: (590.21, 553.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3387)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 236, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (260.31, 126.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 877)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 741, 1131)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3069)
[M::mem_pestat] mean and std.dev: (686.30, 575.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4038)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (293, 380, 930)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2204)
[M::mem_pestat] mean and std.dev: (528.32, 452.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2841)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696998 sequences (100000198 bp) in 2.574 CPU sec, 2.837 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 282068, 30, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 317, 645)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1503)
[M::mem_pestat] mean and std.dev: (331.63, 172.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1932)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 236, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (260.00, 126.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 873)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 535, 1800)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5040)
[M::mem_pestat] mean and std.dev: (1106.62, 1271.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6660)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 386, 1079)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2731)
[M::mem_pestat] mean and std.dev: (628.83, 537.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3557)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696934 sequences (100000052 bp) in 1.836 CPU sec, 1.848 real sec...
[M::mem_process_seqs] Processed 696962 reads in 192.002 CPU sec, 6.210 real sec
sorting block 30, #reads = 1073356 mem = 536877803 peak = 947933184
[M::mem_process_seqs] Processed 697066 reads in 139.038 CPU sec, 4.502 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281490, 22, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 382, 1714)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4694)
[M::mem_pestat] mean and std.dev: (846.23, 973.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6184)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 236, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (259.74, 126.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 873)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (341, 483, 1467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3719)
[M::mem_pestat] mean and std.dev: (710.40, 650.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4845)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 345, 932)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2374)
[M::mem_pestat] mean and std.dev: (491.60, 425.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3095)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 31, #reads = 1072821 mem = 536884173 peak = 947933184
[M::process] read 697130 sequences (100000076 bp) in 2.506 CPU sec, 2.745 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 281272, 29, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 255, 1504)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4164)
[M::mem_pestat] mean and std.dev: (540.80, 614.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5494)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 235, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (259.07, 125.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 869)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 317, 1451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3915)
[M::mem_pestat] mean and std.dev: (764.32, 1000.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5147)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 361, 1253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3291)
[M::mem_pestat] mean and std.dev: (811.78, 775.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4310)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697342 sequences (100000228 bp) in 1.856 CPU sec, 1.871 real sec...
[M::mem_process_seqs] Processed 696998 reads in 191.902 CPU sec, 6.197 real sec
[M::mem_process_seqs] Processed 696934 reads in 131.426 CPU sec, 4.232 real sec
sorting block 32, #reads = 1073133 mem = 536878691 peak = 947933184
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 281576, 26, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 287, 924)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2404)
[M::mem_pestat] mean and std.dev: (534.84, 523.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3144)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 234, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (257.48, 124.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (353, 752, 1331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3287)
[M::mem_pestat] mean and std.dev: (805.83, 709.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4265)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (344, 652, 1650)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4262)
[M::mem_pestat] mean and std.dev: (850.79, 799.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5568)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697478 sequences (100000237 bp) in 2.584 CPU sec, 3.164 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 281275, 27, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 282, 780)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1932)
[M::mem_pestat] mean and std.dev: (484.78, 458.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2508)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 233, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (257.34, 124.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 860)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (574, 1069, 1983)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4801)
[M::mem_pestat] mean and std.dev: (1292.64, 1051.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6210)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 398, 1043)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2649)
[M::mem_pestat] mean and std.dev: (693.09, 626.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3452)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697476 sequences (100000283 bp) in 1.910 CPU sec, 1.940 real sec...
[M::mem_process_seqs] Processed 697130 reads in 189.969 CPU sec, 6.156 real sec
[M::mem_process_seqs] Processed 697342 reads in 130.932 CPU sec, 4.235 real sec
sorting block 33, #reads = 1073734 mem = 536879211 peak = 947933184
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 281903, 28, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 490, 916)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2356)
[M::mem_pestat] mean and std.dev: (592.34, 558.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3076)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 232, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (256.82, 124.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 863)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (463, 764, 1840)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4594)
[M::mem_pestat] mean and std.dev: (891.63, 753.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5971)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 373, 811)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2013)
[M::mem_pestat] mean and std.dev: (490.86, 393.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2614)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697176 sequences (100000186 bp) in 2.280 CPU sec, 2.904 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 281503, 33, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 303, 713)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1803)
[M::mem_pestat] mean and std.dev: (417.22, 354.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2348)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 233, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (257.18, 124.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 860)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (453, 666, 2042)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5220)
[M::mem_pestat] mean and std.dev: (1069.23, 1300.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6809)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 448, 749)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1827)
[M::mem_pestat] mean and std.dev: (511.52, 437.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2366)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697054 sequences (100000240 bp) in 1.718 CPU sec, 1.798 real sec...
[M::mem_process_seqs] Processed 697478 reads in 187.444 CPU sec, 6.075 real sec
sorting block 34, #reads = 1073438 mem = 536878918 peak = 947933184
[M::mem_process_seqs] Processed 697476 reads in 131.490 CPU sec, 4.230 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 281375, 31, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 383, 1394)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3792)
[M::mem_pestat] mean and std.dev: (705.21, 704.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4991)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 233, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (256.77, 124.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 856)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (268, 497, 1196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3052)
[M::mem_pestat] mean and std.dev: (767.90, 772.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3980)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 456, 870)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2126)
[M::mem_pestat] mean and std.dev: (460.33, 324.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2754)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697048 sequences (100000283 bp) in 2.526 CPU sec, 2.752 real sec...
sorting block 35, #reads = 1073264 mem = 536877431 peak = 947933184
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281413, 23, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 442, 1521)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4087)
[M::mem_pestat] mean and std.dev: (676.76, 646.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5370)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 234, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (258.15, 124.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (503, 1067, 1674)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4016)
[M::mem_pestat] mean and std.dev: (1064.52, 677.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5187)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 530, 2400)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6748)
[M::mem_pestat] mean and std.dev: (1282.36, 1464.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8922)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696676 sequences (100000002 bp) in 1.883 CPU sec, 1.910 real sec...
[M::mem_process_seqs] Processed 697176 reads in 186.078 CPU sec, 6.019 real sec
[M::mem_process_seqs] Processed 697054 reads in 131.403 CPU sec, 4.248 real sec
sorting block 36, #reads = 1072146 mem = 536878078 peak = 947933184
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 281177, 24, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 413, 1141)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3055)
[M::mem_pestat] mean and std.dev: (630.84, 585.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4012)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 234, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (257.91, 124.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 645, 2261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6357)
[M::mem_pestat] mean and std.dev: (944.81, 1088.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8405)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 565, 1760)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4784)
[M::mem_pestat] mean and std.dev: (873.30, 782.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6296)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696552 sequences (100000147 bp) in 2.504 CPU sec, 2.758 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 281749, 18, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 395, 1025)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2687)
[M::mem_pestat] mean and std.dev: (603.22, 562.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3518)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 235, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (258.46, 124.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 865)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 504, 1155)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3191)
[M::mem_pestat] mean and std.dev: (666.28, 616.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4209)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 320, 688)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1574)
[M::mem_pestat] mean and std.dev: (394.20, 298.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2017)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696564 sequences (100000225 bp) in 1.735 CPU sec, 1.859 real sec...
[M::mem_process_seqs] Processed 697048 reads in 188.437 CPU sec, 6.085 real sec
[M::mem_process_seqs] Processed 696676 reads in 130.726 CPU sec, 4.219 real sec
sorting block 37, #reads = 1072197 mem = 536880336 peak = 947933184
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281215, 23, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 446, 1209)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3273)
[M::mem_pestat] mean and std.dev: (529.27, 526.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4305)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 235, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (257.54, 123.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 857)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (275, 791, 1711)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4583)
[M::mem_pestat] mean and std.dev: (1405.96, 1600.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7808)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (262, 466, 2325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6451)
[M::mem_pestat] mean and std.dev: (964.26, 1404.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8514)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696268 sequences (100000227 bp) in 2.987 CPU sec, 3.132 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 280781, 21, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 358, 696)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1658)
[M::mem_pestat] mean and std.dev: (401.49, 291.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2139)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 236, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (259.23, 125.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 869)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 616, 1346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3734)
[M::mem_pestat] mean and std.dev: (646.21, 575.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4928)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 365, 680)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1540)
[M::mem_pestat] mean and std.dev: (407.90, 299.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1970)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696382 sequences (100000235 bp) in 1.861 CPU sec, 1.875 real sec...
[M::mem_process_seqs] Processed 696552 reads in 192.323 CPU sec, 6.158 real sec
[M::mem_process_seqs] Processed 696564 reads in 132.297 CPU sec, 4.230 real sec
sorting block 38, #reads = 1073090 mem = 536881598 peak = 947933184
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 281617, 23, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (278, 639, 1363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3533)
[M::mem_pestat] mean and std.dev: (841.42, 853.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4618)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 237, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (260.66, 126.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 877)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 457, 2693)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7709)
[M::mem_pestat] mean and std.dev: (1128.00, 1213.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10217)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (291, 575, 798)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1812)
[M::mem_pestat] mean and std.dev: (554.43, 387.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2319)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696116 sequences (100000183 bp) in 2.967 CPU sec, 3.160 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 282004, 24, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 436, 1155)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3053)
[M::mem_pestat] mean and std.dev: (605.74, 560.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4002)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 236, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (259.78, 125.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 869)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 940, 2055)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5883)
[M::mem_pestat] mean and std.dev: (1178.42, 1005.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7797)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 287, 600)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1438)
[M::mem_pestat] mean and std.dev: (390.35, 298.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1857)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695894 sequences (100000131 bp) in 1.750 CPU sec, 1.815 real sec...
[M::mem_process_seqs] Processed 696268 reads in 190.417 CPU sec, 6.106 real sec
sorting block 39, #reads = 1072119 mem = 536876924 peak = 947933184
[M::mem_process_seqs] Processed 696382 reads in 129.741 CPU sec, 4.138 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 281711, 25, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 403, 643)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1585)
[M::mem_pestat] mean and std.dev: (433.31, 342.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2056)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 237, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (260.30, 125.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 874)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (246, 585, 1823)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4977)
[M::mem_pestat] mean and std.dev: (1007.76, 1077.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6554)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 413, 1883)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5169)
[M::mem_pestat] mean and std.dev: (1087.07, 1202.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6812)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 40, #reads = 1073191 mem = 536884394 peak = 984514560
[M::process] read 695244 sequences (100000232 bp) in 2.688 CPU sec, 3.112 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 280871, 37, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 426, 904)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2280)
[M::mem_pestat] mean and std.dev: (528.45, 401.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2968)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 238, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (260.60, 124.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (333, 951, 2493)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6813)
[M::mem_pestat] mean and std.dev: (1194.85, 1174.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8973)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (262, 550, 834)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1978)
[M::mem_pestat] mean and std.dev: (593.07, 450.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2550)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695334 sequences (100000174 bp) in 1.755 CPU sec, 1.805 real sec...
[M::mem_process_seqs] Processed 696116 reads in 188.952 CPU sec, 6.079 real sec
[M::mem_process_seqs] Processed 695894 reads in 130.272 CPU sec, 4.183 real sec
sorting block 41, #reads = 1072594 mem = 536875797 peak = 984514560
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 281539, 15, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 476, 1323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3577)
[M::mem_pestat] mean and std.dev: (771.76, 725.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4704)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 239, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697)
[M::mem_pestat] mean and std.dev: (261.71, 125.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 875)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (420, 1163, 2560)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6840)
[M::mem_pestat] mean and std.dev: (1501.80, 1362.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8980)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 264, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1045)
[M::mem_pestat] mean and std.dev: (286.55, 167.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1337)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694930 sequences (100000224 bp) in 2.652 CPU sec, 2.975 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 281533, 31, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 477, 1325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3597)
[M::mem_pestat] mean and std.dev: (793.88, 792.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4733)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 240, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 703)
[M::mem_pestat] mean and std.dev: (262.77, 126.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 883)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 387, 1295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3559)
[M::mem_pestat] mean and std.dev: (812.30, 964.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4691)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 315, 848)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2032)
[M::mem_pestat] mean and std.dev: (462.18, 361.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2624)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694852 sequences (100000057 bp) in 1.856 CPU sec, 1.906 real sec...
[M::mem_process_seqs] Processed 695244 reads in 191.554 CPU sec, 6.178 real sec
[M::mem_process_seqs] Processed 695334 reads in 132.241 CPU sec, 4.253 real sec
sorting block 42, #reads = 1071239 mem = 536879824 peak = 984514560
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 280697, 31, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 571, 2014)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5598)
[M::mem_pestat] mean and std.dev: (1098.36, 1122.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7390)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 241, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 704)
[M::mem_pestat] mean and std.dev: (263.71, 126.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 884)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 427, 1352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3560)
[M::mem_pestat] mean and std.dev: (824.55, 863.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4664)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 511, 771)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1863)
[M::mem_pestat] mean and std.dev: (578.18, 456.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2409)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697180 sequences (100000162 bp) in 3.003 CPU sec, 3.483 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 280493, 27, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (352, 484, 1839)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4813)
[M::mem_pestat] mean and std.dev: (1018.48, 1094.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6300)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 242, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 713)
[M::mem_pestat] mean and std.dev: (265.66, 128.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 896)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (525, 844, 2179)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5487)
[M::mem_pestat] mean and std.dev: (1291.50, 1232.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7141)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 307, 1099)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2931)
[M::mem_pestat] mean and std.dev: (668.72, 725.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3847)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701436 sequences (100000142 bp) in 1.993 CPU sec, 2.008 real sec...
[M::mem_process_seqs] Processed 694930 reads in 193.550 CPU sec, 6.231 real sec
sorting block 43, #reads = 1072853 mem = 536877976 peak = 984514560
[M::mem_process_seqs] Processed 694852 reads in 136.338 CPU sec, 4.355 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 281286, 30, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (252, 358, 1105)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2811)
[M::mem_pestat] mean and std.dev: (529.46, 501.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3664)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 235, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (258.58, 125.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (497, 1137, 1872)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4622)
[M::mem_pestat] mean and std.dev: (1189.11, 870.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5997)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 548, 956)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2462)
[M::mem_pestat] mean and std.dev: (547.80, 442.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3215)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 44, #reads = 1069825 mem = 536880122 peak = 984760320
[M::process] read 700986 sequences (100000208 bp) in 2.893 CPU sec, 3.160 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 282896, 32, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 457, 1752)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4768)
[M::mem_pestat] mean and std.dev: (802.15, 892.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6276)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 223, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 657)
[M::mem_pestat] mean and std.dev: (246.42, 118.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 825)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (402, 671, 2200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5796)
[M::mem_pestat] mean and std.dev: (1300.87, 1383.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7594)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 408, 1039)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2629)
[M::mem_pestat] mean and std.dev: (547.91, 392.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3424)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699976 sequences (100000083 bp) in 1.776 CPU sec, 1.786 real sec...
[M::mem_process_seqs] Processed 697180 reads in 200.435 CPU sec, 6.706 real sec
[M::mem_process_seqs] Processed 701436 reads in 133.290 CPU sec, 4.272 real sec
sorting block 45, #reads = 1070805 mem = 536876642 peak = 984760320
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 282842, 24, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 312, 668)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1584)
[M::mem_pestat] mean and std.dev: (412.96, 295.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2042)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 225, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 662)
[M::mem_pestat] mean and std.dev: (248.54, 120.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 831)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (91, 585, 1242)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3544)
[M::mem_pestat] mean and std.dev: (786.46, 768.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4695)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 310, 534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1172)
[M::mem_pestat] mean and std.dev: (326.45, 161.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1491)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699916 sequences (100000057 bp) in 2.824 CPU sec, 3.140 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 282807, 16, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 235, 656)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1612)
[M::mem_pestat] mean and std.dev: (411.14, 378.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2090)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 228, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 669)
[M::mem_pestat] mean and std.dev: (251.05, 121.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 840)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (377, 680, 1997)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5237)
[M::mem_pestat] mean and std.dev: (902.81, 830.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6857)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (293, 366, 1292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3290)
[M::mem_pestat] mean and std.dev: (483.30, 369.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4289)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699470 sequences (100000010 bp) in 1.690 CPU sec, 1.727 real sec...
[M::mem_process_seqs] Processed 700986 reads in 198.952 CPU sec, 6.477 real sec
[M::mem_process_seqs] Processed 699976 reads in 132.836 CPU sec, 4.263 real sec
sorting block 46, #reads = 1073139 mem = 536878299 peak = 984760320
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 282638, 32, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 350, 412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 854)
[M::mem_pestat] mean and std.dev: (260.59, 110.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1075)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 228, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 672)
[M::mem_pestat] mean and std.dev: (251.64, 121.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 844)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (459, 846, 1254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2844)
[M::mem_pestat] mean and std.dev: (697.61, 439.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3639)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 326, 814)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2056)
[M::mem_pestat] mean and std.dev: (414.97, 362.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2677)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698862 sequences (100000229 bp) in 2.844 CPU sec, 3.326 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 282626, 31, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 438, 631)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1435)
[M::mem_pestat] mean and std.dev: (488.32, 353.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1902)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 229, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 676)
[M::mem_pestat] mean and std.dev: (252.81, 122.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 849)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (621, 1036, 1597)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3549)
[M::mem_pestat] mean and std.dev: (977.41, 628.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4525)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 409, 865)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2199)
[M::mem_pestat] mean and std.dev: (538.59, 475.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2866)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698548 sequences (100000044 bp) in 1.692 CPU sec, 1.713 real sec...
[M::mem_process_seqs] Processed 699916 reads in 190.989 CPU sec, 6.170 real sec
sorting block 47, #reads = 1075604 mem = 536881241 peak = 984760320
[M::mem_process_seqs] Processed 699470 reads in 138.254 CPU sec, 4.447 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 282377, 23, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 371, 630)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1480)
[M::mem_pestat] mean and std.dev: (421.59, 291.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1905)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 231, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (255.10, 123.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (355, 938, 1930)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5080)
[M::mem_pestat] mean and std.dev: (1264.91, 1075.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6655)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (316, 452, 1239)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3085)
[M::mem_pestat] mean and std.dev: (771.00, 522.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4008)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 48, #reads = 1074413 mem = 536879799 peak = 986365952
[M::process] read 697968 sequences (100000137 bp) in 2.747 CPU sec, 3.031 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 282268, 26, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 872, 1771)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4847)
[M::mem_pestat] mean and std.dev: (1009.94, 903.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6385)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 232, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (254.94, 123.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 451, 1042)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2638)
[M::mem_pestat] mean and std.dev: (595.38, 595.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3436)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 278, 1269)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3425)
[M::mem_pestat] mean and std.dev: (603.23, 531.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4503)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698862 reads in 189.005 CPU sec, 6.132 real sec
[M::process] read 697606 sequences (100000015 bp) in 1.744 CPU sec, 1.866 real sec...
[M::mem_process_seqs] Processed 698548 reads in 130.353 CPU sec, 4.218 real sec
sorting block 49, #reads = 1074199 mem = 536879090 peak = 986365952
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 281722, 23, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 290, 730)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1784)
[M::mem_pestat] mean and std.dev: (433.89, 367.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2311)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 234, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (256.52, 123.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 863)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (468, 928, 1032)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2160)
[M::mem_pestat] mean and std.dev: (647.35, 379.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2724)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 524, 870)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2142)
[M::mem_pestat] mean and std.dev: (543.79, 414.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2778)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697428 sequences (100000228 bp) in 2.458 CPU sec, 2.941 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 281952, 20, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 256, 523)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1187)
[M::mem_pestat] mean and std.dev: (325.13, 191.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1519)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 235, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (257.59, 123.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 484, 1411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3943)
[M::mem_pestat] mean and std.dev: (776.21, 850.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5209)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 279, 1149)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3125)
[M::mem_pestat] mean and std.dev: (720.90, 876.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4228)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697450 sequences (100000157 bp) in 1.702 CPU sec, 1.706 real sec...
[M::mem_process_seqs] Processed 697968 reads in 191.743 CPU sec, 6.221 real sec
[M::mem_process_seqs] Processed 697606 reads in 133.346 CPU sec, 4.299 real sec
sorting block 50, #reads = 1074132 mem = 536879063 peak = 986365952
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 281979, 23, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 415, 1710)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4666)
[M::mem_pestat] mean and std.dev: (828.02, 809.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6144)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 235, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 694)
[M::mem_pestat] mean and std.dev: (258.63, 125.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 872)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (281, 648, 1773)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4757)
[M::mem_pestat] mean and std.dev: (1018.91, 914.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6249)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 399, 1306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3484)
[M::mem_pestat] mean and std.dev: (579.78, 693.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4573)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697148 sequences (100000073 bp) in 2.820 CPU sec, 3.302 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 281468, 43, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (332, 643, 903)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2045)
[M::mem_pestat] mean and std.dev: (579.93, 388.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2616)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 236, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 694)
[M::mem_pestat] mean and std.dev: (258.75, 124.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 872)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 484, 689)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1789)
[M::mem_pestat] mean and std.dev: (438.92, 352.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2339)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 263, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 741)
[M::mem_pestat] mean and std.dev: (261.70, 121.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 929)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696518 sequences (100000286 bp) in 1.781 CPU sec, 1.813 real sec...
[M::mem_process_seqs] Processed 697428 reads in 190.410 CPU sec, 6.146 real sec
sorting block 51, #reads = 1073212 mem = 536880423 peak = 986365952
[M::mem_process_seqs] Processed 697450 reads in 139.491 CPU sec, 4.490 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 281551, 30, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 458, 882)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2246)
[M::mem_pestat] mean and std.dev: (435.00, 327.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2928)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 236, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697)
[M::mem_pestat] mean and std.dev: (259.65, 125.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 876)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (437, 895, 2195)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5711)
[M::mem_pestat] mean and std.dev: (1339.57, 1341.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7469)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (272, 569, 1048)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2600)
[M::mem_pestat] mean and std.dev: (596.56, 489.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3376)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 52, #reads = 1072409 mem = 536881984 peak = 986365952
[M::process] read 697170 sequences (100000062 bp) in 2.769 CPU sec, 3.172 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 281462, 19, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (255, 385, 1521)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4053)
[M::mem_pestat] mean and std.dev: (971.62, 1061.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5319)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 237, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701)
[M::mem_pestat] mean and std.dev: (260.92, 126.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 881)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (484, 748, 1349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3079)
[M::mem_pestat] mean and std.dev: (909.18, 762.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3957)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 306, 540)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1228)
[M::mem_pestat] mean and std.dev: (375.23, 269.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1572)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697148 reads in 189.121 CPU sec, 6.095 real sec
[M::process] read 696334 sequences (100000264 bp) in 1.836 CPU sec, 1.964 real sec...
[M::mem_process_seqs] Processed 696518 reads in 130.574 CPU sec, 4.187 real sec
sorting block 53, #reads = 1072669 mem = 536879045 peak = 986365952
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 281259, 19, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 290, 570)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1364)
[M::mem_pestat] mean and std.dev: (412.10, 331.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1761)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 236, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (260.20, 126.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 877)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (102, 175, 426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1074)
[M::mem_pestat] mean and std.dev: (242.06, 218.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1398)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 452, 755)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1865)
[M::mem_pestat] mean and std.dev: (360.38, 209.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2420)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696608 sequences (100000262 bp) in 2.699 CPU sec, 3.053 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 281590, 34, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 521, 1166)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3040)
[M::mem_pestat] mean and std.dev: (718.88, 651.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3977)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 238, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 702)
[M::mem_pestat] mean and std.dev: (261.59, 126.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 882)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 554, 1347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3553)
[M::mem_pestat] mean and std.dev: (819.65, 779.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4656)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 336, 601)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1301)
[M::mem_pestat] mean and std.dev: (367.98, 226.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1651)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696576 sequences (100000054 bp) in 1.827 CPU sec, 1.863 real sec...
[M::mem_process_seqs] Processed 697170 reads in 188.607 CPU sec, 6.069 real sec
[M::mem_process_seqs] Processed 696334 reads in 131.746 CPU sec, 4.222 real sec
sorting block 54, #reads = 1072096 mem = 536878628 peak = 986365952
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 281998, 31, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 321, 702)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1736)
[M::mem_pestat] mean and std.dev: (388.27, 281.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2253)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 237, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701)
[M::mem_pestat] mean and std.dev: (261.24, 126.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 881)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (312, 801, 1768)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4680)
[M::mem_pestat] mean and std.dev: (904.52, 850.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6136)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 417, 1336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3590)
[M::mem_pestat] mean and std.dev: (722.95, 743.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4717)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696632 sequences (100000068 bp) in 2.737 CPU sec, 3.017 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 281126, 25, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 320, 857)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2215)
[M::mem_pestat] mean and std.dev: (491.10, 449.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2894)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 235, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (259.43, 125.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 869)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 514, 1544)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4208)
[M::mem_pestat] mean and std.dev: (892.04, 995.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5540)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 329, 982)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2476)
[M::mem_pestat] mean and std.dev: (516.26, 434.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3223)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696614 sequences (100000195 bp) in 1.804 CPU sec, 1.921 real sec...
[M::mem_process_seqs] Processed 696608 reads in 191.329 CPU sec, 6.190 real sec
[M::mem_process_seqs] Processed 696576 reads in 133.054 CPU sec, 4.308 real sec
sorting block 55, #reads = 1071950 mem = 536880349 peak = 986365952
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 281354, 18, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 763, 1744)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4750)
[M::mem_pestat] mean and std.dev: (1135.26, 1194.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6253)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 235, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (259.03, 125.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 869)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (373, 590, 1204)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2866)
[M::mem_pestat] mean and std.dev: (677.18, 527.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3697)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (292, 509, 1050)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2566)
[M::mem_pestat] mean and std.dev: (592.83, 472.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3324)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696992 sequences (100000028 bp) in 2.944 CPU sec, 3.121 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 281539, 21, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (324, 688, 1811)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4785)
[M::mem_pestat] mean and std.dev: (1107.26, 1079.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6272)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 235, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (258.56, 124.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 865)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (253, 808, 1237)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3205)
[M::mem_pestat] mean and std.dev: (789.15, 718.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4189)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (267, 434, 1971)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5379)
[M::mem_pestat] mean and std.dev: (1207.41, 1364.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7083)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696666 sequences (100000239 bp) in 1.779 CPU sec, 1.793 real sec...
[M::mem_process_seqs] Processed 696632 reads in 191.287 CPU sec, 6.152 real sec
sorting block 56, #reads = 1073146 mem = 536876961 peak = 986365952
[M::mem_process_seqs] Processed 696614 reads in 130.812 CPU sec, 4.228 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281765, 15, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 311, 954)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2506)
[M::mem_pestat] mean and std.dev: (543.21, 628.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3282)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 235, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 686)
[M::mem_pestat] mean and std.dev: (258.21, 124.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 861)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (125, 753, 1083)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2999)
[M::mem_pestat] mean and std.dev: (777.71, 798.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3972)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 239, 587)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1461)
[M::mem_pestat] mean and std.dev: (390.47, 359.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1898)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 57, #reads = 1072322 mem = 536880050 peak = 1014861824
[M::process] read 696610 sequences (100000137 bp) in 2.908 CPU sec, 3.013 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 280905, 25, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 443, 641)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1607)
[M::mem_pestat] mean and std.dev: (432.29, 399.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2090)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 235, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (258.60, 124.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 865)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (440, 1013, 1359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3197)
[M::mem_pestat] mean and std.dev: (831.09, 487.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4116)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 330, 477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1011)
[M::mem_pestat] mean and std.dev: (306.61, 145.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1278)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696432 sequences (100000139 bp) in 1.762 CPU sec, 1.797 real sec...
[M::mem_process_seqs] Processed 696992 reads in 193.664 CPU sec, 6.239 real sec
[M::mem_process_seqs] Processed 696666 reads in 129.626 CPU sec, 4.184 real sec
sorting block 58, #reads = 1073786 mem = 536881185 peak = 1014861824
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 281321, 24, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 268, 863)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2277)
[M::mem_pestat] mean and std.dev: (511.85, 485.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2984)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 235, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (258.55, 124.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 865)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (519, 696, 1296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2850)
[M::mem_pestat] mean and std.dev: (833.65, 624.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3627)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 209, 980)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2646)
[M::mem_pestat] mean and std.dev: (550.16, 627.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3479)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696384 sequences (100000088 bp) in 2.690 CPU sec, 3.075 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 281753, 25, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 453, 838)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2090)
[M::mem_pestat] mean and std.dev: (474.00, 318.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2716)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 235, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 686)
[M::mem_pestat] mean and std.dev: (258.04, 123.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 861)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 384, 852)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2188)
[M::mem_pestat] mean and std.dev: (435.17, 290.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2856)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 448, 1235)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3323)
[M::mem_pestat] mean and std.dev: (704.22, 759.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4367)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696336 sequences (100000212 bp) in 1.718 CPU sec, 1.944 real sec...
[M::mem_process_seqs] Processed 696610 reads in 197.036 CPU sec, 6.593 real sec
[M::mem_process_seqs] Processed 696432 reads in 128.897 CPU sec, 4.150 real sec
sorting block 59, #reads = 1071234 mem = 536880238 peak = 1014861824
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 281547, 22, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 326, 816)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2096)
[M::mem_pestat] mean and std.dev: (376.57, 341.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2736)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 236, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (259.22, 124.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 869)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 326, 1512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4116)
[M::mem_pestat] mean and std.dev: (678.68, 740.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5418)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 425, 1307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3563)
[M::mem_pestat] mean and std.dev: (707.90, 784.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4691)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696120 sequences (100000145 bp) in 2.762 CPU sec, 3.093 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 281660, 16, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 815, 3400)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9712)
[M::mem_pestat] mean and std.dev: (2012.38, 2541.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12868)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 236, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (259.85, 125.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 873)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 287, 433)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 943)
[M::mem_pestat] mean and std.dev: (315.29, 190.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1198)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 382, 1251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3295)
[M::mem_pestat] mean and std.dev: (604.56, 567.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4317)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696384 reads in 187.944 CPU sec, 6.075 real sec
[M::process] read 695906 sequences (100000238 bp) in 1.767 CPU sec, 1.846 real sec...
sorting block 60, #reads = 1072823 mem = 536878523 peak = 1014861824
[M::mem_process_seqs] Processed 696336 reads in 127.016 CPU sec, 4.101 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 281300, 30, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 612, 1545)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4171)
[M::mem_pestat] mean and std.dev: (852.23, 773.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5484)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 236, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (259.99, 125.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 873)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 572, 1008)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2738)
[M::mem_pestat] mean and std.dev: (754.07, 687.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3603)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 521, 1094)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2876)
[M::mem_pestat] mean and std.dev: (662.88, 574.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3767)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 61, #reads = 1072740 mem = 536893335 peak = 1029128192
[M::process] read 695890 sequences (100000269 bp) in 2.803 CPU sec, 3.153 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 281027, 29, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (285, 535, 1024)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2502)
[M::mem_pestat] mean and std.dev: (684.13, 507.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3241)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 237, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (260.56, 125.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (508, 629, 1018)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2038)
[M::mem_pestat] mean and std.dev: (601.75, 331.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2548)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 510, 1939)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5363)
[M::mem_pestat] mean and std.dev: (913.98, 913.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7075)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696120 reads in 189.711 CPU sec, 6.106 real sec
[M::process] read 695824 sequences (100000094 bp) in 1.956 CPU sec, 2.013 real sec...
[M::mem_process_seqs] Processed 695906 reads in 128.117 CPU sec, 4.087 real sec
sorting block 62, #reads = 1072858 mem = 536876824 peak = 1029128192
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281042, 23, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 500, 832)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2032)
[M::mem_pestat] mean and std.dev: (565.08, 355.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2632)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 237, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (261.15, 126.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 874)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (249, 1124, 1534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4104)
[M::mem_pestat] mean and std.dev: (930.23, 751.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5389)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 865, 1771)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4823)
[M::mem_pestat] mean and std.dev: (1301.68, 1371.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6789)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695544 sequences (100000280 bp) in 2.947 CPU sec, 3.427 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 281125, 16, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 253, 1015)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2729)
[M::mem_pestat] mean and std.dev: (600.14, 649.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3586)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 238, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 702)
[M::mem_pestat] mean and std.dev: (262.22, 127.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 882)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (99, 573, 1429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4089)
[M::mem_pestat] mean and std.dev: (689.27, 788.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5419)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 600, 1392)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3750)
[M::mem_pestat] mean and std.dev: (755.32, 696.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4929)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695890 reads in 190.875 CPU sec, 6.147 real sec
[M::process] read 695286 sequences (100000086 bp) in 1.764 CPU sec, 1.865 real sec...
[M::mem_process_seqs] Processed 695824 reads in 129.722 CPU sec, 4.158 real sec
sorting block 63, #reads = 1071790 mem = 536879734 peak = 1029128192
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 281212, 30, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 425, 1631)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4427)
[M::mem_pestat] mean and std.dev: (767.29, 805.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5825)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 239, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (262.33, 126.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (555, 1644, 2020)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4950)
[M::mem_pestat] mean and std.dev: (1594.23, 1022.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6415)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 328, 620)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1374)
[M::mem_pestat] mean and std.dev: (406.44, 249.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1751)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695046 sequences (100000148 bp) in 2.790 CPU sec, 3.327 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 281184, 35, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 290, 542)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1210)
[M::mem_pestat] mean and std.dev: (312.29, 196.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1544)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 240, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 703)
[M::mem_pestat] mean and std.dev: (263.19, 126.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 883)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (424, 676, 1149)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2599)
[M::mem_pestat] mean and std.dev: (758.58, 599.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3324)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 575, 1363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3633)
[M::mem_pestat] mean and std.dev: (720.76, 733.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4768)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695544 reads in 189.463 CPU sec, 6.122 real sec
[M::process] read 694542 sequences (100000147 bp) in 1.758 CPU sec, 1.819 real sec...
sorting block 64, #reads = 1073379 mem = 536878652 peak = 1029128192
[M::mem_process_seqs] Processed 695286 reads in 131.437 CPU sec, 4.210 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 281629, 19, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 282, 768)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1930)
[M::mem_pestat] mean and std.dev: (413.03, 413.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2511)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 241, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 707)
[M::mem_pestat] mean and std.dev: (263.88, 127.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 888)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (382, 528, 3305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9151)
[M::mem_pestat] mean and std.dev: (1613.32, 1814.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12074)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 331, 696)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1638)
[M::mem_pestat] mean and std.dev: (375.62, 273.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2109)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 65, #reads = 1071737 mem = 536878834 peak = 1029128192
[M::process] read 694546 sequences (100000253 bp) in 3.285 CPU sec, 3.577 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 280262, 25, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (269, 386, 1328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3446)
[M::mem_pestat] mean and std.dev: (690.35, 626.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4505)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 242, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 702)
[M::mem_pestat] mean and std.dev: (264.11, 126.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 881)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (287, 860, 1713)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4565)
[M::mem_pestat] mean and std.dev: (1024.96, 888.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5991)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (276, 520, 1660)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4428)
[M::mem_pestat] mean and std.dev: (863.51, 869.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5812)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695046 reads in 186.428 CPU sec, 6.012 real sec
[M::process] read 699322 sequences (100000166 bp) in 1.826 CPU sec, 1.834 real sec...
[M::mem_process_seqs] Processed 694542 reads in 128.293 CPU sec, 4.123 real sec
sorting block 66, #reads = 1072788 mem = 536892052 peak = 1029128192
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 281030, 37, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (121, 256, 754)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2020)
[M::mem_pestat] mean and std.dev: (281.82, 212.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2653)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 242, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 708)
[M::mem_pestat] mean and std.dev: (265.20, 127.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 889)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 753, 2822)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8158)
[M::mem_pestat] mean and std.dev: (1363.67, 1657.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10826)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 285, 632)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1442)
[M::mem_pestat] mean and std.dev: (351.84, 241.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1847)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701608 sequences (100000087 bp) in 3.121 CPU sec, 3.339 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 282311, 26, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 295, 949)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2477)
[M::mem_pestat] mean and std.dev: (487.76, 433.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3241)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 228, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 673)
[M::mem_pestat] mean and std.dev: (252.23, 121.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 845)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (309, 581, 2260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6162)
[M::mem_pestat] mean and std.dev: (1281.00, 1278.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8113)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 345, 584)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1252)
[M::mem_pestat] mean and std.dev: (425.91, 266.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1586)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701342 sequences (100000160 bp) in 1.773 CPU sec, 1.912 real sec...
[M::mem_process_seqs] Processed 694546 reads in 192.917 CPU sec, 6.201 real sec
[M::mem_process_seqs] Processed 699322 reads in 132.512 CPU sec, 4.253 real sec
sorting block 67, #reads = 1071323 mem = 536878253 peak = 1029128192
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 283644, 24, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 350, 1157)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2981)
[M::mem_pestat] mean and std.dev: (644.59, 576.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3893)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 223, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 660)
[M::mem_pestat] mean and std.dev: (247.03, 120.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 829)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (94, 179, 803)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2221)
[M::mem_pestat] mean and std.dev: (322.30, 421.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2930)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 295, 603)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1419)
[M::mem_pestat] mean and std.dev: (314.08, 195.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1827)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700884 sequences (100000174 bp) in 2.725 CPU sec, 2.920 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 282581, 26, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (285, 751, 1781)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4773)
[M::mem_pestat] mean and std.dev: (937.09, 1147.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6269)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 224, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (248.44, 121.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 455, 1091)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2811)
[M::mem_pestat] mean and std.dev: (658.96, 680.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3671)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 428, 885)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2209)
[M::mem_pestat] mean and std.dev: (525.33, 374.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2871)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701608 reads in 189.231 CPU sec, 6.095 real sec
[M::process] read 699858 sequences (100000276 bp) in 1.957 CPU sec, 2.150 real sec...
sorting block 68, #reads = 1072812 mem = 536879282 peak = 1029128192
[M::mem_process_seqs] Processed 701342 reads in 130.275 CPU sec, 4.181 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 283104, 31, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 233, 1037)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2769)
[M::mem_pestat] mean and std.dev: (432.30, 392.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3635)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 225, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 670)
[M::mem_pestat] mean and std.dev: (250.09, 122.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 842)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (493, 1880, 2564)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6706)
[M::mem_pestat] mean and std.dev: (1699.24, 1282.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8777)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 280, 1034)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2706)
[M::mem_pestat] mean and std.dev: (509.59, 509.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3542)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699678 sequences (100000144 bp) in 2.913 CPU sec, 3.226 real sec...
sorting block 69, #reads = 1075579 mem = 536877031 peak = 1029128192
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 282815, 35, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 333, 1152)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3148)
[M::mem_pestat] mean and std.dev: (583.81, 615.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4146)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 227, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 672)
[M::mem_pestat] mean and std.dev: (251.91, 122.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 844)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (379, 544, 760)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1522)
[M::mem_pestat] mean and std.dev: (491.81, 275.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1903)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 217, 645)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1637)
[M::mem_pestat] mean and std.dev: (319.11, 321.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2133)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700884 reads in 185.190 CPU sec, 5.955 real sec
[M::process] read 699550 sequences (100000071 bp) in 1.793 CPU sec, 1.845 real sec...
[M::mem_process_seqs] Processed 699858 reads in 131.077 CPU sec, 4.195 real sec
sorting block 70, #reads = 1076256 mem = 536880944 peak = 1029128192
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 282662, 21, 15)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 337, 635)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1535)
[M::mem_pestat] mean and std.dev: (382.56, 294.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1985)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 228, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 678)
[M::mem_pestat] mean and std.dev: (253.05, 123.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 852)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 306, 1301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3583)
[M::mem_pestat] mean and std.dev: (520.47, 553.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4724)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (424, 577, 1383)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3301)
[M::mem_pestat] mean and std.dev: (781.00, 637.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4260)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699026 sequences (100000001 bp) in 2.473 CPU sec, 2.881 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 282626, 29, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 251, 1272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3504)
[M::mem_pestat] mean and std.dev: (431.53, 554.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4620)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 230, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (254.25, 124.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 857)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (831, 942, 1794)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3720)
[M::mem_pestat] mean and std.dev: (1226.64, 828.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4683)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 346, 716)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1746)
[M::mem_pestat] mean and std.dev: (482.32, 466.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2350)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698600 sequences (100000009 bp) in 1.826 CPU sec, 1.895 real sec...
[M::mem_process_seqs] Processed 699678 reads in 189.774 CPU sec, 6.356 real sec
[M::mem_process_seqs] Processed 699550 reads in 131.689 CPU sec, 4.283 real sec
sorting block 71, #reads = 1074898 mem = 536881071 peak = 1029128192
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 282733, 23, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (274, 517, 771)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1765)
[M::mem_pestat] mean and std.dev: (523.40, 359.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2262)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 229, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (254.07, 124.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 857)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (333, 584, 718)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1488)
[M::mem_pestat] mean and std.dev: (512.10, 278.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1873)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 364, 517)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1207)
[M::mem_pestat] mean and std.dev: (334.56, 224.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1552)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698406 sequences (100000008 bp) in 2.823 CPU sec, 3.359 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 281988, 37, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 407, 621)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1401)
[M::mem_pestat] mean and std.dev: (478.17, 350.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1880)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 232, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (256.40, 125.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (298, 650, 2207)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6025)
[M::mem_pestat] mean and std.dev: (889.62, 843.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7934)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 393, 822)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2002)
[M::mem_pestat] mean and std.dev: (479.90, 313.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2592)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698336 sequences (100000133 bp) in 1.751 CPU sec, 1.780 real sec...
[M::mem_process_seqs] Processed 699026 reads in 188.301 CPU sec, 6.067 real sec
[M::mem_process_seqs] Processed 698600 reads in 129.530 CPU sec, 4.152 real sec
sorting block 72, #reads = 1075323 mem = 536879119 peak = 1029128192
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 282244, 21, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (126, 286, 1457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4119)
[M::mem_pestat] mean and std.dev: (972.27, 1256.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5997)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 232, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (256.88, 125.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (616, 1572, 4134)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11170)
[M::mem_pestat] mean and std.dev: (2331.00, 2469.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14688)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (269, 628, 1286)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3320)
[M::mem_pestat] mean and std.dev: (722.09, 600.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4337)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697936 sequences (100000084 bp) in 2.723 CPU sec, 3.077 real sec...
sorting block 73, #reads = 1074754 mem = 536879227 peak = 1031446528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 282370, 27, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 316, 850)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2246)
[M::mem_pestat] mean and std.dev: (464.66, 417.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2944)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 233, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (257.25, 125.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 867)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (266, 958, 1992)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5444)
[M::mem_pestat] mean and std.dev: (1210.12, 1210.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7170)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 307, 828)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2080)
[M::mem_pestat] mean and std.dev: (463.77, 455.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2706)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698406 reads in 188.038 CPU sec, 6.079 real sec
[M::process] read 699254 sequences (100000175 bp) in 1.815 CPU sec, 1.860 real sec...
[M::mem_process_seqs] Processed 698336 reads in 128.403 CPU sec, 4.131 real sec
sorting block 74, #reads = 1074684 mem = 536880694 peak = 1031446528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 281895, 38, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (249, 371, 558)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1176)
[M::mem_pestat] mean and std.dev: (383.00, 244.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1485)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 233, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (257.39, 125.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 867)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 506, 1425)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3837)
[M::mem_pestat] mean and std.dev: (857.63, 794.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5043)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 420, 1681)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4567)
[M::mem_pestat] mean and std.dev: (897.93, 939.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6010)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697572 sequences (100000085 bp) in 2.578 CPU sec, 3.103 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 282340, 20, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 332, 985)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2517)
[M::mem_pestat] mean and std.dev: (555.13, 531.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3283)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 228, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 678)
[M::mem_pestat] mean and std.dev: (253.28, 123.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 852)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (488, 780, 1765)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4319)
[M::mem_pestat] mean and std.dev: (953.25, 760.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5596)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 397, 826)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2042)
[M::mem_pestat] mean and std.dev: (439.68, 332.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2650)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697936 reads in 190.892 CPU sec, 6.154 real sec
[M::process] read 697084 sequences (100000237 bp) in 1.796 CPU sec, 1.799 real sec...
[M::mem_process_seqs] Processed 699254 reads in 130.547 CPU sec, 4.192 real sec
sorting block 75, #reads = 1075082 mem = 536878118 peak = 1031446528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 282228, 23, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (249, 618, 2069)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5709)
[M::mem_pestat] mean and std.dev: (779.07, 717.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7529)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 235, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697)
[M::mem_pestat] mean and std.dev: (258.98, 126.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 876)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (542, 1129, 2424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6188)
[M::mem_pestat] mean and std.dev: (1576.52, 1473.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8070)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 270, 1006)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2612)
[M::mem_pestat] mean and std.dev: (519.73, 498.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3415)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697488 sequences (100000016 bp) in 2.839 CPU sec, 3.246 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 281800, 27, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 361, 780)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1928)
[M::mem_pestat] mean and std.dev: (356.88, 282.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2502)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 235, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (259.67, 126.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 880)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (383, 916, 1171)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2747)
[M::mem_pestat] mean and std.dev: (781.56, 486.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3535)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 335, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 885)
[M::mem_pestat] mean and std.dev: (297.53, 146.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1105)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697038 sequences (100000240 bp) in 1.805 CPU sec, 1.812 real sec...
[M::mem_process_seqs] Processed 697572 reads in 187.495 CPU sec, 6.025 real sec
[M::mem_process_seqs] Processed 697084 reads in 129.469 CPU sec, 4.130 real sec
sorting block 76, #reads = 1075148 mem = 536878579 peak = 1031446528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 281646, 20, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 317, 851)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2175)
[M::mem_pestat] mean and std.dev: (489.40, 458.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2837)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 235, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 694)
[M::mem_pestat] mean and std.dev: (258.85, 126.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 872)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 714, 1985)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5413)
[M::mem_pestat] mean and std.dev: (977.95, 881.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7127)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 298, 682)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1598)
[M::mem_pestat] mean and std.dev: (414.91, 358.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2056)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696928 sequences (100000092 bp) in 2.621 CPU sec, 3.221 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 282019, 27, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 461, 1071)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2897)
[M::mem_pestat] mean and std.dev: (547.35, 521.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3810)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 235, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 694)
[M::mem_pestat] mean and std.dev: (259.00, 125.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 872)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (347, 922, 3120)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8666)
[M::mem_pestat] mean and std.dev: (1753.63, 1778.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11439)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 282, 881)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2219)
[M::mem_pestat] mean and std.dev: (425.52, 357.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2888)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697488 reads in 188.935 CPU sec, 6.100 real sec
sorting block 77, #reads = 1073922 mem = 536877917 peak = 1031446528
[M::mem_process_seqs] Processed 697038 reads in 132.771 CPU sec, 4.234 real sec
[M::process] read 696982 sequences (100000222 bp) in 2.621 CPU sec, 2.690 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 281209, 29, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 309, 701)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1719)
[M::mem_pestat] mean and std.dev: (331.67, 233.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2228)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 235, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (259.28, 125.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 869)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (311, 500, 1431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3671)
[M::mem_pestat] mean and std.dev: (904.43, 903.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4791)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 400, 907)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2293)
[M::mem_pestat] mean and std.dev: (630.80, 589.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2988)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 78, #reads = 1074045 mem = 536881406 peak = 1048920064
[M::process] read 697152 sequences (100000027 bp) in 2.741 CPU sec, 3.165 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 281704, 32, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (344, 589, 840)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1832)
[M::mem_pestat] mean and std.dev: (577.77, 309.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2328)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 234, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (258.71, 125.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 654, 1347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3705)
[M::mem_pestat] mean and std.dev: (869.10, 939.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4884)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (264, 488, 1794)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4854)
[M::mem_pestat] mean and std.dev: (710.56, 615.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6384)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696928 reads in 187.277 CPU sec, 6.067 real sec
[M::process] read 697238 sequences (100000218 bp) in 1.711 CPU sec, 1.835 real sec...
[M::mem_process_seqs] Processed 696982 reads in 130.260 CPU sec, 4.183 real sec
sorting block 79, #reads = 1072997 mem = 536880593 peak = 1048920064
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 281594, 28, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 281, 379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701)
[M::mem_pestat] mean and std.dev: (260.62, 99.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 862)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 234, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (257.99, 125.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 461, 3427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9791)
[M::mem_pestat] mean and std.dev: (1455.89, 1669.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12973)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 355, 794)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1890)
[M::mem_pestat] mean and std.dev: (451.39, 367.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2438)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696760 sequences (100000002 bp) in 2.759 CPU sec, 3.305 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 281595, 25, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 403, 1404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3754)
[M::mem_pestat] mean and std.dev: (675.19, 690.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4929)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 234, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (257.66, 124.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (319, 476, 1085)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2617)
[M::mem_pestat] mean and std.dev: (635.13, 498.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3383)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 287, 379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 719)
[M::mem_pestat] mean and std.dev: (296.20, 142.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 889)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697152 reads in 190.411 CPU sec, 6.164 real sec
[M::process] read 696646 sequences (100000179 bp) in 1.827 CPU sec, 1.835 real sec...
[M::mem_process_seqs] Processed 697238 reads in 133.641 CPU sec, 4.306 real sec
sorting block 80, #reads = 1073195 mem = 536886495 peak = 1048920064
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281847, 34, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 303, 855)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2207)
[M::mem_pestat] mean and std.dev: (593.92, 615.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3056)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 234, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (258.11, 124.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 1163, 2584)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7288)
[M::mem_pestat] mean and std.dev: (1266.88, 1018.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9640)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 394, 655)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1529)
[M::mem_pestat] mean and std.dev: (478.07, 336.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1966)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696756 sequences (100000186 bp) in 2.992 CPU sec, 3.496 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 281490, 28, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 311, 1700)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4760)
[M::mem_pestat] mean and std.dev: (764.61, 913.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6290)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 234, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (257.86, 124.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 857)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (408, 594, 1711)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4317)
[M::mem_pestat] mean and std.dev: (1019.54, 1097.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5620)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (328, 486, 1266)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3142)
[M::mem_pestat] mean and std.dev: (947.00, 924.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4646)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696538 sequences (100000258 bp) in 1.755 CPU sec, 1.764 real sec...
[M::mem_process_seqs] Processed 696760 reads in 191.791 CPU sec, 6.182 real sec
sorting block 81, #reads = 1071761 mem = 536878365 peak = 1048920064
[M::mem_process_seqs] Processed 696646 reads in 133.645 CPU sec, 4.322 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 281771, 30, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 293, 1229)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3297)
[M::mem_pestat] mean and std.dev: (516.74, 483.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4331)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 235, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 686)
[M::mem_pestat] mean and std.dev: (258.36, 124.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 861)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 685, 1095)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2947)
[M::mem_pestat] mean and std.dev: (788.03, 677.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3873)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 311, 487)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 975)
[M::mem_pestat] mean and std.dev: (299.24, 119.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1219)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 82, #reads = 1072763 mem = 536879847 peak = 1057673216
[M::process] read 696638 sequences (100000036 bp) in 3.149 CPU sec, 3.435 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 281557, 27, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 452, 980)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2550)
[M::mem_pestat] mean and std.dev: (557.14, 452.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3335)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 234, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 686)
[M::mem_pestat] mean and std.dev: (258.39, 124.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 861)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 403, 1864)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5250)
[M::mem_pestat] mean and std.dev: (846.63, 985.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6943)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (316, 526, 1111)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2701)
[M::mem_pestat] mean and std.dev: (670.18, 510.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3496)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695790 sequences (100000240 bp) in 1.691 CPU sec, 1.699 real sec...
[M::mem_process_seqs] Processed 696756 reads in 190.679 CPU sec, 6.128 real sec
[M::mem_process_seqs] Processed 696538 reads in 140.326 CPU sec, 4.507 real sec
sorting block 83, #reads = 1071649 mem = 536882878 peak = 1057673216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 281445, 23, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (276, 440, 1520)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4008)
[M::mem_pestat] mean and std.dev: (865.26, 941.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5252)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 235, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 686)
[M::mem_pestat] mean and std.dev: (258.38, 124.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 861)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 439, 1292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3550)
[M::mem_pestat] mean and std.dev: (684.71, 674.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4679)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 414, 1471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3957)
[M::mem_pestat] mean and std.dev: (836.54, 830.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5200)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695792 sequences (100000145 bp) in 2.617 CPU sec, 3.003 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 281205, 27, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (281, 590, 1146)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2876)
[M::mem_pestat] mean and std.dev: (706.87, 503.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3741)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 238, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (260.77, 125.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 397, 2185)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6237)
[M::mem_pestat] mean and std.dev: (1101.22, 1311.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8263)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 341, 563)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1189)
[M::mem_pestat] mean and std.dev: (350.31, 200.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1502)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695608 sequences (100000270 bp) in 1.719 CPU sec, 1.875 real sec...
[M::mem_process_seqs] Processed 696638 reads in 192.272 CPU sec, 6.200 real sec
[M::mem_process_seqs] Processed 695790 reads in 131.887 CPU sec, 4.246 real sec
sorting block 84, #reads = 1072174 mem = 536879811 peak = 1057673216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 281290, 26, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 255, 1761)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4971)
[M::mem_pestat] mean and std.dev: (847.19, 1038.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6576)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 238, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (260.51, 125.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 634, 1390)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3834)
[M::mem_pestat] mean and std.dev: (1046.65, 1083.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5380)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 293, 697)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1685)
[M::mem_pestat] mean and std.dev: (428.44, 347.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2179)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695412 sequences (100000113 bp) in 2.998 CPU sec, 3.189 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 281200, 18, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 235, 831)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2189)
[M::mem_pestat] mean and std.dev: (417.89, 386.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2868)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 238, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 694)
[M::mem_pestat] mean and std.dev: (261.02, 125.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (285, 1132, 2665)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7425)
[M::mem_pestat] mean and std.dev: (1670.67, 1613.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9805)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 538, 1302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3524)
[M::mem_pestat] mean and std.dev: (670.65, 631.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4635)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695306 sequences (100000248 bp) in 1.751 CPU sec, 1.798 real sec...
[M::mem_process_seqs] Processed 695792 reads in 190.588 CPU sec, 6.114 real sec
sorting block 85, #reads = 1071714 mem = 536880108 peak = 1057673216
[M::mem_process_seqs] Processed 695608 reads in 129.673 CPU sec, 4.149 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 281500, 39, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (371, 948, 1138)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2672)
[M::mem_pestat] mean and std.dev: (731.29, 472.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3439)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 238, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (260.77, 124.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 867)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (666, 747, 1204)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2280)
[M::mem_pestat] mean and std.dev: (871.03, 517.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2940)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 394, 1118)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2850)
[M::mem_pestat] mean and std.dev: (545.19, 451.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3716)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 86, #reads = 1072193 mem = 536876943 peak = 1058344960
[M::process] read 695184 sequences (100000083 bp) in 2.690 CPU sec, 2.996 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 281657, 25, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 422, 1478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4032)
[M::mem_pestat] mean and std.dev: (754.45, 906.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5309)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 239, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697)
[M::mem_pestat] mean and std.dev: (261.64, 124.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 875)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 378, 2539)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7311)
[M::mem_pestat] mean and std.dev: (1474.92, 1807.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9697)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 624, 1232)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3210)
[M::mem_pestat] mean and std.dev: (708.65, 653.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4199)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694884 sequences (100000252 bp) in 1.796 CPU sec, 1.828 real sec...
[M::mem_process_seqs] Processed 695412 reads in 188.465 CPU sec, 6.064 real sec
[M::mem_process_seqs] Processed 695306 reads in 127.598 CPU sec, 4.083 real sec
sorting block 87, #reads = 1072059 mem = 536879766 peak = 1058344960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 281283, 28, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 351, 810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1940)
[M::mem_pestat] mean and std.dev: (394.96, 276.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2505)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 240, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701)
[M::mem_pestat] mean and std.dev: (262.95, 125.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 880)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 732, 1253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3217)
[M::mem_pestat] mean and std.dev: (752.04, 598.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4199)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 357, 935)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2403)
[M::mem_pestat] mean and std.dev: (590.00, 581.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3137)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695046 sequences (100000254 bp) in 3.125 CPU sec, 3.337 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 280643, 13, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 467, 658)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1678)
[M::mem_pestat] mean and std.dev: (413.46, 338.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2188)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 241, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 704)
[M::mem_pestat] mean and std.dev: (263.80, 126.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 884)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 797, 1185)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3155)
[M::mem_pestat] mean and std.dev: (664.00, 534.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4140)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 275, 777)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2001)
[M::mem_pestat] mean and std.dev: (418.80, 378.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2613)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696898 sequences (100000001 bp) in 1.800 CPU sec, 1.809 real sec...
[M::mem_process_seqs] Processed 695184 reads in 185.836 CPU sec, 5.936 real sec
[M::mem_process_seqs] Processed 694884 reads in 124.074 CPU sec, 3.948 real sec
sorting block 88, #reads = 1072449 mem = 536881793 peak = 1058344960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 281190, 24, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (293, 537, 1076)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2642)
[M::mem_pestat] mean and std.dev: (672.95, 556.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3425)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 242, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 710)
[M::mem_pestat] mean and std.dev: (265.25, 128.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 892)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (257, 498, 2144)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5918)
[M::mem_pestat] mean and std.dev: (1105.67, 1302.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7805)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 295, 626)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1436)
[M::mem_pestat] mean and std.dev: (414.21, 307.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1841)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706458 sequences (100000152 bp) in 3.273 CPU sec, 3.342 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 281684, 22, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (313, 379, 1733)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4573)
[M::mem_pestat] mean and std.dev: (833.26, 925.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5993)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 236, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (260.38, 126.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 877)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (28, 308, 1067)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3145)
[M::mem_pestat] mean and std.dev: (539.60, 632.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4184)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 472, 979)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2533)
[M::mem_pestat] mean and std.dev: (617.54, 566.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3310)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705206 sequences (100000163 bp) in 1.971 CPU sec, 1.979 real sec...
[M::mem_process_seqs] Processed 695046 reads in 188.293 CPU sec, 5.990 real sec
sorting block 89, #reads = 1071311 mem = 536878727 peak = 1058344960
[M::mem_process_seqs] Processed 696898 reads in 135.012 CPU sec, 4.300 real sec
sorting block 90, #reads = 1070393 mem = 536879370 peak = 1058344960
[M::process] read 703952 sequences (100000107 bp) in 2.768 CPU sec, 3.247 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 285212, 15, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 410, 1442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3798)
[M::mem_pestat] mean and std.dev: (771.58, 667.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4976)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 213, 308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 626)
[M::mem_pestat] mean and std.dev: (237.60, 116.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 785)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 513, 1164)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3054)
[M::mem_pestat] mean and std.dev: (661.79, 694.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3999)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 269, 393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 901)
[M::mem_pestat] mean and std.dev: (260.18, 166.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1155)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703256 sequences (100000155 bp) in 1.858 CPU sec, 1.909 real sec...
[M::mem_process_seqs] Processed 705206 reads in 110.276 CPU sec, 3.487 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 285273, 13, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 433, 938)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2394)
[M::mem_pestat] mean and std.dev: (537.13, 491.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3122)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 210, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 615)
[M::mem_pestat] mean and std.dev: (234.15, 113.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 771)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 893, 2083)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5901)
[M::mem_pestat] mean and std.dev: (1186.83, 1275.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7810)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 286, 600)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1414)
[M::mem_pestat] mean and std.dev: (386.48, 306.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1821)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 284416, 42, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 384, 782)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1934)
[M::mem_pestat] mean and std.dev: (569.51, 504.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2587)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 216, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 636)
[M::mem_pestat] mean and std.dev: (240.76, 117.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 798)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 477, 854)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2220)
[M::mem_pestat] mean and std.dev: (476.94, 428.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2903)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 397, 787)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1933)
[M::mem_pestat] mean and std.dev: (458.33, 304.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2506)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706458 reads in 312.519 CPU sec, 9.990 real sec
[M::process] read 702706 sequences (100000081 bp) in 2.012 CPU sec, 2.042 real sec...
sorting block 91, #reads = 1076128 mem = 536878589 peak = 1058344960
[M::mem_process_seqs] Processed 703952 reads in 161.263 CPU sec, 5.165 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 283866, 23, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 304, 735)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1885)
[M::mem_pestat] mean and std.dev: (396.94, 344.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2460)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 217, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 646)
[M::mem_pestat] mean and std.dev: (242.99, 119.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 811)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (424, 597, 2493)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6631)
[M::mem_pestat] mean and std.dev: (988.76, 933.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8700)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 623, 1317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3569)
[M::mem_pestat] mean and std.dev: (801.56, 739.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4695)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702136 sequences (100000132 bp) in 3.145 CPU sec, 3.485 real sec...
sorting block 92, #reads = 1077732 mem = 536878841 peak = 1058344960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 284203, 23, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 255, 811)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2027)
[M::mem_pestat] mean and std.dev: (357.23, 328.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2635)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 219, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 647)
[M::mem_pestat] mean and std.dev: (244.39, 119.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 812)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (634, 1147, 3708)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9856)
[M::mem_pestat] mean and std.dev: (1580.13, 1380.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12930)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 292, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 975)
[M::mem_pestat] mean and std.dev: (313.10, 177.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1241)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701320 sequences (100000222 bp) in 2.097 CPU sec, 2.160 real sec...
[M::mem_process_seqs] Processed 703256 reads in 201.316 CPU sec, 6.462 real sec
[M::mem_process_seqs] Processed 702706 reads in 139.036 CPU sec, 4.443 real sec
sorting block 93, #reads = 1075638 mem = 536882007 peak = 1058344960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 284334, 35, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 408, 868)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2224)
[M::mem_pestat] mean and std.dev: (402.69, 277.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2902)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 220, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 656)
[M::mem_pestat] mean and std.dev: (245.96, 120.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 824)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 691, 1225)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3145)
[M::mem_pestat] mean and std.dev: (817.85, 742.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4105)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 377, 1231)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3191)
[M::mem_pestat] mean and std.dev: (588.90, 531.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4171)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701342 sequences (100000044 bp) in 2.750 CPU sec, 3.135 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 283982, 25, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (301, 462, 870)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2008)
[M::mem_pestat] mean and std.dev: (515.41, 292.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2577)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 222, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (248.31, 121.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 830)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (463, 1031, 1844)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4606)
[M::mem_pestat] mean and std.dev: (1021.43, 822.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5987)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 347, 852)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2104)
[M::mem_pestat] mean and std.dev: (481.89, 394.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2730)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700730 sequences (100000083 bp) in 1.789 CPU sec, 1.830 real sec...
[M::mem_process_seqs] Processed 702136 reads in 199.302 CPU sec, 6.412 real sec
[M::mem_process_seqs] Processed 701320 reads in 137.304 CPU sec, 4.400 real sec
sorting block 94, #reads = 1074647 mem = 536877668 peak = 1058344960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 283704, 23, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 272, 612)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1404)
[M::mem_pestat] mean and std.dev: (331.00, 226.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1800)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 223, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (249.02, 122.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 638, 1233)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3305)
[M::mem_pestat] mean and std.dev: (740.00, 577.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4341)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 479, 859)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2195)
[M::mem_pestat] mean and std.dev: (449.72, 331.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2863)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700492 sequences (100000068 bp) in 2.672 CPU sec, 2.955 real sec...
[M::process] read 699926 sequences (100000206 bp) in 2.000 CPU sec, 2.006 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 283424, 19, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 231, 1228)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3404)
[M::mem_pestat] mean and std.dev: (620.79, 766.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4492)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 224, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 673)
[M::mem_pestat] mean and std.dev: (250.70, 123.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 846)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 564, 2096)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5974)
[M::mem_pestat] mean and std.dev: (1199.11, 1279.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7913)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 372, 1239)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3371)
[M::mem_pestat] mean and std.dev: (672.62, 745.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4437)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701342 reads in 210.875 CPU sec, 6.777 real sec
sorting block 95, #reads = 1075469 mem = 536880374 peak = 1058344960
[M::mem_process_seqs] Processed 700730 reads in 136.882 CPU sec, 4.362 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 283219, 20, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 269, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 605)
[M::mem_pestat] mean and std.dev: (236.10, 86.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 744)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 226, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 677)
[M::mem_pestat] mean and std.dev: (252.11, 124.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 851)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (672, 861, 1410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2886)
[M::mem_pestat] mean and std.dev: (915.50, 506.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3624)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 349, 1062)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2760)
[M::mem_pestat] mean and std.dev: (535.35, 521.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3609)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699794 sequences (100000074 bp) in 2.951 CPU sec, 3.461 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 283209, 28, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 392, 909)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2381)
[M::mem_pestat] mean and std.dev: (556.03, 536.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3117)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 227, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 681)
[M::mem_pestat] mean and std.dev: (253.34, 124.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 856)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (491, 1028, 1338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3032)
[M::mem_pestat] mean and std.dev: (855.69, 436.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3879)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 350, 1130)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2950)
[M::mem_pestat] mean and std.dev: (531.65, 545.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3860)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699482 sequences (100000041 bp) in 1.812 CPU sec, 1.818 real sec...
[M::mem_process_seqs] Processed 700492 reads in 190.251 CPU sec, 6.097 real sec
sorting block 96, #reads = 1073604 mem = 536878338 peak = 1058344960
[M::mem_process_seqs] Processed 699926 reads in 130.125 CPU sec, 4.132 real sec
sorting block 97, #reads = 1074494 mem = 536878632 peak = 1065893888
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 282281, 39, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (300, 845, 1454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3762)
[M::mem_pestat] mean and std.dev: (956.90, 794.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4916)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 227, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 681)
[M::mem_pestat] mean and std.dev: (253.23, 124.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 856)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (343, 891, 1700)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4414)
[M::mem_pestat] mean and std.dev: (1037.64, 831.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5771)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 347, 1151)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3037)
[M::mem_pestat] mean and std.dev: (588.66, 603.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3980)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699256 sequences (100000296 bp) in 2.871 CPU sec, 2.996 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 282379, 15, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 363, 1522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4204)
[M::mem_pestat] mean and std.dev: (945.71, 939.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5545)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 229, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (255.34, 126.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 865)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (414, 758, 2827)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7653)
[M::mem_pestat] mean and std.dev: (1608.33, 1929.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10066)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (293, 678, 1513)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3953)
[M::mem_pestat] mean and std.dev: (675.46, 532.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5173)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698840 sequences (100000112 bp) in 1.790 CPU sec, 1.790 real sec...
[M::mem_process_seqs] Processed 699794 reads in 185.589 CPU sec, 5.899 real sec
[M::mem_process_seqs] Processed 699482 reads in 128.382 CPU sec, 4.071 real sec
sorting block 98, #reads = 1073369 mem = 536877240 peak = 1065893888
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 282470, 25, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 473, 1184)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3180)
[M::mem_pestat] mean and std.dev: (639.71, 601.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4178)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 228, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (255.38, 126.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (433, 868, 1023)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2203)
[M::mem_pestat] mean and std.dev: (727.13, 439.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2793)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 320, 564)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1328)
[M::mem_pestat] mean and std.dev: (306.79, 164.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1710)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698360 sequences (100000212 bp) in 3.040 CPU sec, 3.202 real sec...
[M::process] read 698206 sequences (100000110 bp) in 1.799 CPU sec, 1.800 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 282500, 25, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 316, 810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2008)
[M::mem_pestat] mean and std.dev: (531.26, 479.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2607)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 230, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (255.89, 126.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 865)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 378, 1552)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4292)
[M::mem_pestat] mean and std.dev: (669.33, 640.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5662)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 563, 1793)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4947)
[M::mem_pestat] mean and std.dev: (1007.21, 1067.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6524)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699256 reads in 193.238 CPU sec, 6.131 real sec
sorting block 99, #reads = 1072348 mem = 536881477 peak = 1065893888
[M::process] read 698228 sequences (100000261 bp) in 2.007 CPU sec, 2.014 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 281492, 26, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 443, 1385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3809)
[M::mem_pestat] mean and std.dev: (822.35, 959.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5021)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 231, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (257.01, 126.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (29, 406, 710)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2072)
[M::mem_pestat] mean and std.dev: (380.12, 340.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2753)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 241, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 746)
[M::mem_pestat] mean and std.dev: (236.21, 106.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 936)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698360 reads in 106.716 CPU sec, 3.605 real sec
[M::mem_process_seqs] Processed 698840 reads in 266.277 CPU sec, 8.695 real sec
sorting block 100, #reads = 1071203 mem = 536879145 peak = 1065893888
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 281710, 17, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 241, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1080)
[M::mem_pestat] mean and std.dev: (277.66, 216.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1395)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 231, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (257.17, 126.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (522, 798, 1558)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3630)
[M::mem_pestat] mean and std.dev: (961.41, 734.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4666)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 285, 533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1221)
[M::mem_pestat] mean and std.dev: (374.15, 270.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1565)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697776 sequences (100000089 bp) in 2.517 CPU sec, 2.626 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 281833, 30, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (373, 627, 1316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3202)
[M::mem_pestat] mean and std.dev: (711.03, 445.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4145)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 232, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (256.69, 125.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 863)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (295, 693, 1383)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3559)
[M::mem_pestat] mean and std.dev: (754.61, 556.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4647)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (289, 413, 1089)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2689)
[M::mem_pestat] mean and std.dev: (650.17, 496.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3489)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697812 sequences (100000037 bp) in 1.739 CPU sec, 1.739 real sec...
[M::mem_process_seqs] Processed 698206 reads in 208.108 CPU sec, 6.751 real sec
sorting block 101, #reads = 1071730 mem = 536880106 peak = 1065893888
[M::mem_process_seqs] Processed 698228 reads in 127.430 CPU sec, 4.049 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 281843, 24, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 268, 929)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2379)
[M::mem_pestat] mean and std.dev: (365.52, 275.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3104)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 233, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (258.23, 126.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (300, 1371, 1952)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5256)
[M::mem_pestat] mean and std.dev: (1378.54, 1139.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6908)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 459, 1517)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4255)
[M::mem_pestat] mean and std.dev: (813.85, 809.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5624)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697810 sequences (100000240 bp) in 2.855 CPU sec, 3.087 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 281852, 25, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 338, 885)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2233)
[M::mem_pestat] mean and std.dev: (537.50, 527.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2907)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 232, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (257.34, 125.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 867)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (714, 823, 2730)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6762)
[M::mem_pestat] mean and std.dev: (1553.52, 1350.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8778)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 421, 1987)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5599)
[M::mem_pestat] mean and std.dev: (1048.93, 1198.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7405)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697788 sequences (100000300 bp) in 1.925 CPU sec, 1.931 real sec...
[M::mem_process_seqs] Processed 697776 reads in 181.490 CPU sec, 5.758 real sec
sorting block 102, #reads = 1070144 mem = 536878159 peak = 1065893888
[M::mem_process_seqs] Processed 697812 reads in 122.450 CPU sec, 3.877 real sec
sorting block 103, #reads = 1071567 mem = 536878238 peak = 1065893888
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 281986, 18, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (262, 897, 1686)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4534)
[M::mem_pestat] mean and std.dev: (1134.06, 1012.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5958)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 232, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (257.50, 125.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 867)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 516, 983)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2487)
[M::mem_pestat] mean and std.dev: (542.31, 495.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3239)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 479, 1275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3447)
[M::mem_pestat] mean and std.dev: (900.68, 937.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4649)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698084 sequences (100000259 bp) in 2.875 CPU sec, 2.975 real sec...
[M::process] read 697048 sequences (100000100 bp) in 1.900 CPU sec, 1.906 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 281712, 22, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 397, 808)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2068)
[M::mem_pestat] mean and std.dev: (542.94, 509.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2698)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 232, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (257.26, 125.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 863)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (57, 570, 1008)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2910)
[M::mem_pestat] mean and std.dev: (690.24, 793.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3864)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (263, 380, 999)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2471)
[M::mem_pestat] mean and std.dev: (522.17, 423.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3207)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697810 reads in 196.170 CPU sec, 6.237 real sec
[M::process] read 697122 sequences (100000267 bp) in 2.093 CPU sec, 2.098 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 282428, 24, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 329, 1354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3698)
[M::mem_pestat] mean and std.dev: (660.57, 649.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4870)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 232, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684)
[M::mem_pestat] mean and std.dev: (256.41, 125.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 859)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (259, 806, 2259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6259)
[M::mem_pestat] mean and std.dev: (1213.61, 1058.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8259)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 295, 1080)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2810)
[M::mem_pestat] mean and std.dev: (676.88, 729.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3675)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698084 reads in 118.126 CPU sec, 3.996 real sec
sorting block 104, #reads = 1070628 mem = 536888781 peak = 1065893888
[M::mem_process_seqs] Processed 697788 reads in 296.815 CPU sec, 9.720 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 281858, 34, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (303, 435, 1071)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2607)
[M::mem_pestat] mean and std.dev: (609.91, 525.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3375)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 234, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 694)
[M::mem_pestat] mean and std.dev: (259.13, 126.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 872)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 447, 1380)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3686)
[M::mem_pestat] mean and std.dev: (737.45, 764.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4839)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 331, 762)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1844)
[M::mem_pestat] mean and std.dev: (493.44, 353.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2385)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 105, #reads = 1070630 mem = 536877229 peak = 1077325824
[M::process] read 697264 sequences (100000002 bp) in 2.679 CPU sec, 2.959 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 281571, 33, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 448, 1512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4142)
[M::mem_pestat] mean and std.dev: (921.85, 1139.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5480)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 234, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (257.82, 124.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 489, 1045)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2605)
[M::mem_pestat] mean and std.dev: (552.13, 481.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3385)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 355, 1082)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2806)
[M::mem_pestat] mean and std.dev: (647.77, 674.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3668)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696538 sequences (100000232 bp) in 1.850 CPU sec, 1.854 real sec...
[M::mem_process_seqs] Processed 697048 reads in 229.275 CPU sec, 7.298 real sec
[M::mem_process_seqs] Processed 697122 reads in 139.671 CPU sec, 4.434 real sec
sorting block 106, #reads = 1069611 mem = 536880646 peak = 1077325824
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 281994, 20, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 404, 966)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2450)
[M::mem_pestat] mean and std.dev: (524.67, 443.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3192)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 234, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (257.97, 125.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (358, 663, 898)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1978)
[M::mem_pestat] mean and std.dev: (551.83, 336.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2518)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 239, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 715)
[M::mem_pestat] mean and std.dev: (271.81, 117.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 887)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696822 sequences (100000025 bp) in 3.079 CPU sec, 3.206 real sec...
[M::process] read 696616 sequences (100000252 bp) in 1.933 CPU sec, 1.941 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281479, 19, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 260, 658)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1640)
[M::mem_pestat] mean and std.dev: (481.50, 484.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2418)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 235, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (258.98, 125.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 865)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (426, 1232, 1929)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4935)
[M::mem_pestat] mean and std.dev: (1172.33, 851.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6438)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 392, 1047)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2679)
[M::mem_pestat] mean and std.dev: (560.11, 519.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3495)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697264 reads in 203.449 CPU sec, 6.469 real sec
[M::mem_process_seqs] Processed 696538 reads in 140.434 CPU sec, 4.467 real sec
sorting block 107, #reads = 1070160 mem = 536878712 peak = 1077325824
[M::process] read 696876 sequences (100000176 bp) in 2.905 CPU sec, 3.002 real sec...
[M::process] read 696628 sequences (100000080 bp) in 1.928 CPU sec, 1.936 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 281756, 35, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 364, 1154)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3018)
[M::mem_pestat] mean and std.dev: (697.62, 685.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3950)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 235, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (258.55, 124.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 865)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 721, 1888)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5152)
[M::mem_pestat] mean and std.dev: (980.97, 867.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6784)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 236, 639)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1633)
[M::mem_pestat] mean and std.dev: (345.83, 312.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2130)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696616 reads in 115.653 CPU sec, 3.660 real sec
sorting block 108, #reads = 1069482 mem = 536889323 peak = 1077325824
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281596, 32, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 557, 1336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3648)
[M::mem_pestat] mean and std.dev: (661.58, 606.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4804)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 234, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (257.61, 123.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 860)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (370, 1385, 2935)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8065)
[M::mem_pestat] mean and std.dev: (1940.59, 2135.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10630)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 333, 1598)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4470)
[M::mem_pestat] mean and std.dev: (798.64, 887.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5906)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 281420, 35, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 352, 815)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1961)
[M::mem_pestat] mean and std.dev: (413.73, 274.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2534)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 234, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (258.02, 124.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (105, 660, 1323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3759)
[M::mem_pestat] mean and std.dev: (591.45, 650.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4977)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 317, 810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1974)
[M::mem_pestat] mean and std.dev: (387.97, 294.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2556)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697176 sequences (100000219 bp) in 2.007 CPU sec, 2.018 real sec...
[M::mem_process_seqs] Processed 696822 reads in 312.717 CPU sec, 9.945 real sec
[M::mem_process_seqs] Processed 696876 reads in 157.395 CPU sec, 5.038 real sec
sorting block 109, #reads = 1069122 mem = 536877602 peak = 1077325824
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281979, 39, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 469, 1211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3221)
[M::mem_pestat] mean and std.dev: (816.30, 736.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4226)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 235, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (258.77, 125.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 865)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (382, 699, 1427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3517)
[M::mem_pestat] mean and std.dev: (874.53, 793.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4562)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (297, 449, 883)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2055)
[M::mem_pestat] mean and std.dev: (578.71, 434.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2641)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701390 sequences (100000105 bp) in 3.221 CPU sec, 3.385 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 281666, 13, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 657, 1677)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4751)
[M::mem_pestat] mean and std.dev: (909.31, 1043.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6288)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 233, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (258.20, 125.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (446, 901, 1194)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2690)
[M::mem_pestat] mean and std.dev: (794.54, 470.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3438)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 300, 541)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1151)
[M::mem_pestat] mean and std.dev: (358.28, 189.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1456)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707576 sequences (100000182 bp) in 1.880 CPU sec, 1.878 real sec...
[M::mem_process_seqs] Processed 696628 reads in 187.913 CPU sec, 5.954 real sec
sorting block 110, #reads = 1069140 mem = 536878630 peak = 1077325824
[M::mem_process_seqs] Processed 697176 reads in 125.399 CPU sec, 3.972 real sec
sorting block 111, #reads = 1068737 mem = 536879468 peak = 1077325824
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 283047, 20, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 366, 1505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4059)
[M::mem_pestat] mean and std.dev: (870.24, 941.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5336)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 222, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 657)
[M::mem_pestat] mean and std.dev: (246.95, 120.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 825)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (91, 1010, 1509)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4345)
[M::mem_pestat] mean and std.dev: (859.68, 763.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5763)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 401, 801)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2011)
[M::mem_pestat] mean and std.dev: (470.48, 379.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2616)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705918 sequences (100000043 bp) in 2.465 CPU sec, 2.581 real sec...
[M::process] read 704816 sequences (100000182 bp) in 1.857 CPU sec, 1.860 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 285101, 21, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 255, 434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1014)
[M::mem_pestat] mean and std.dev: (258.12, 144.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1304)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 207, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 599)
[M::mem_pestat] mean and std.dev: (230.06, 110.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 750)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 478, 1295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3597)
[M::mem_pestat] mean and std.dev: (660.24, 599.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4748)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 704, 3483)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10009)
[M::mem_pestat] mean and std.dev: (1826.92, 1934.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13272)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701390 reads in 190.256 CPU sec, 6.041 real sec
[M::mem_process_seqs] Processed 707576 reads in 130.280 CPU sec, 4.139 real sec
sorting block 112, #reads = 1069705 mem = 536877832 peak = 1077325824
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 285076, 16, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 263, 946)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2554)
[M::mem_pestat] mean and std.dev: (409.45, 391.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3358)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 211, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 622)
[M::mem_pestat] mean and std.dev: (235.98, 114.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 780)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 1350, 2956)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8386)
[M::mem_pestat] mean and std.dev: (1520.06, 1444.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11101)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 361, 1192)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3104)
[M::mem_pestat] mean and std.dev: (646.24, 698.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4060)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703326 sequences (100000202 bp) in 2.688 CPU sec, 2.742 real sec...
[M::process] read 703036 sequences (100000092 bp) in 1.850 CPU sec, 1.857 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 284492, 13, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 280, 884)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2328)
[M::mem_pestat] mean and std.dev: (510.91, 544.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3050)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 214, 308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 626)
[M::mem_pestat] mean and std.dev: (238.09, 115.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 785)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (501, 836, 2213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5637)
[M::mem_pestat] mean and std.dev: (1235.31, 1095.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7349)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 385, 1932)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5346)
[M::mem_pestat] mean and std.dev: (962.84, 1122.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7053)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705918 reads in 182.669 CPU sec, 5.788 real sec
[M::mem_process_seqs] Processed 704816 reads in 123.311 CPU sec, 3.914 real sec
sorting block 113, #reads = 1071917 mem = 536880913 peak = 1077325824
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 284343, 25, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 245, 1233)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3355)
[M::mem_pestat] mean and std.dev: (574.05, 562.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4416)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 217, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 637)
[M::mem_pestat] mean and std.dev: (241.55, 116.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 799)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (418, 1032, 1741)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4387)
[M::mem_pestat] mean and std.dev: (1180.00, 976.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5710)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 330, 1017)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2629)
[M::mem_pestat] mean and std.dev: (620.57, 609.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3435)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702900 sequences (100000207 bp) in 2.525 CPU sec, 2.651 real sec...
[M::process] read 703060 sequences (100000250 bp) in 1.916 CPU sec, 1.918 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 283688, 21, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 406, 1378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3848)
[M::mem_pestat] mean and std.dev: (645.87, 694.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5083)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 218, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 643)
[M::mem_pestat] mean and std.dev: (242.63, 117.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 807)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (403, 1137, 1875)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4819)
[M::mem_pestat] mean and std.dev: (1108.11, 955.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6291)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 381, 1059)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2689)
[M::mem_pestat] mean and std.dev: (616.67, 566.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3504)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703326 reads in 189.172 CPU sec, 6.159 real sec
sorting block 114, #reads = 1072934 mem = 536877448 peak = 1077325824
[M::mem_process_seqs] Processed 703036 reads in 125.960 CPU sec, 4.038 real sec
sorting block 115, #reads = 1072667 mem = 536880727 peak = 1077325824
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 283962, 27, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 480, 1097)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2833)
[M::mem_pestat] mean and std.dev: (685.85, 611.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3701)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 218, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 641)
[M::mem_pestat] mean and std.dev: (242.75, 117.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 804)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 389, 598)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1458)
[M::mem_pestat] mean and std.dev: (333.48, 241.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1888)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 290, 798)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1966)
[M::mem_pestat] mean and std.dev: (499.12, 425.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2550)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703152 sequences (100000282 bp) in 2.404 CPU sec, 2.527 real sec...
[M::process] read 702976 sequences (100000113 bp) in 1.680 CPU sec, 1.672 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 283978, 27, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 276, 730)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1834)
[M::mem_pestat] mean and std.dev: (476.56, 457.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2386)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 216, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 637)
[M::mem_pestat] mean and std.dev: (241.67, 117.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 799)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (397, 702, 2199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5803)
[M::mem_pestat] mean and std.dev: (1274.07, 1327.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7605)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 273, 1495)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4045)
[M::mem_pestat] mean and std.dev: (679.19, 756.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5320)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702900 reads in 195.183 CPU sec, 6.353 real sec
[M::process] read 701584 sequences (100000212 bp) in 2.006 CPU sec, 2.024 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 283432, 27, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 394, 652)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1508)
[M::mem_pestat] mean and std.dev: (391.66, 248.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1936)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 219, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 649)
[M::mem_pestat] mean and std.dev: (244.00, 119.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 815)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (457, 929, 9597)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 27877)
[M::mem_pestat] mean and std.dev: (3123.81, 3903.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 37017)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (287, 619, 1051)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2579)
[M::mem_pestat] mean and std.dev: (662.95, 577.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3343)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702976 reads in 108.072 CPU sec, 3.526 real sec
sorting block 116, #reads = 1070849 mem = 536879078 peak = 1077325824
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 283661, 13, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 467, 950)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2404)
[M::mem_pestat] mean and std.dev: (560.00, 408.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3131)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 217, 314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 640)
[M::mem_pestat] mean and std.dev: (242.27, 117.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 803)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 751, 1803)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4991)
[M::mem_pestat] mean and std.dev: (961.31, 827.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6585)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 326, 899)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2183)
[M::mem_pestat] mean and std.dev: (532.98, 467.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2825)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703152 reads in 218.449 CPU sec, 7.746 real sec
[M::process] read 701340 sequences (100000091 bp) in 2.320 CPU sec, 2.381 real sec...
sorting block 117, #reads = 1070353 mem = 536882695 peak = 1077325824
[M::mem_process_seqs] Processed 703060 reads in 406.520 CPU sec, 13.773 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 283619, 30, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (358, 756, 1306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3202)
[M::mem_pestat] mean and std.dev: (784.20, 491.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4150)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 222, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (248.29, 121.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 830)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (370, 1109, 1707)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4381)
[M::mem_pestat] mean and std.dev: (1139.43, 778.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5718)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 348, 481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1043)
[M::mem_pestat] mean and std.dev: (336.85, 183.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1324)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701116 sequences (100000012 bp) in 2.335 CPU sec, 2.439 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 283949, 24, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 301, 516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1212)
[M::mem_pestat] mean and std.dev: (316.77, 232.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1560)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 223, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (248.70, 122.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (384, 808, 1800)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4632)
[M::mem_pestat] mean and std.dev: (1199.67, 1048.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6048)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 857, 1737)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4703)
[M::mem_pestat] mean and std.dev: (1074.49, 933.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6186)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700974 sequences (100000119 bp) in 1.800 CPU sec, 1.798 real sec...
[M::mem_process_seqs] Processed 701584 reads in 223.124 CPU sec, 7.059 real sec
sorting block 118, #reads = 1071609 mem = 536877923 peak = 1077325824
[M::mem_process_seqs] Processed 701340 reads in 133.326 CPU sec, 4.225 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 283703, 21, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 461, 623)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1439)
[M::mem_pestat] mean and std.dev: (402.76, 205.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1847)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 224, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667)
[M::mem_pestat] mean and std.dev: (249.66, 122.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 838)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 304, 717)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1727)
[M::mem_pestat] mean and std.dev: (402.53, 292.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2232)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 347, 1078)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2736)
[M::mem_pestat] mean and std.dev: (527.43, 523.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3565)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 119, #reads = 1074146 mem = 536879721 peak = 1077325824
[M::process] read 700572 sequences (100000054 bp) in 2.470 CPU sec, 2.592 real sec...
[M::process] read 699820 sequences (100000152 bp) in 1.852 CPU sec, 1.861 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 283284, 23, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 355, 1350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3698)
[M::mem_pestat] mean and std.dev: (543.51, 554.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4872)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 224, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 670)
[M::mem_pestat] mean and std.dev: (249.91, 123.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 842)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 904, 1994)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5492)
[M::mem_pestat] mean and std.dev: (1040.00, 974.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7241)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 324, 561)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1237)
[M::mem_pestat] mean and std.dev: (327.69, 181.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1575)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701116 reads in 196.150 CPU sec, 6.357 real sec
[M::mem_process_seqs] Processed 700974 reads in 131.136 CPU sec, 4.292 real sec
sorting block 120, #reads = 1071194 mem = 536880619 peak = 1077325824
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 283418, 29, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (313, 857, 1234)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3076)
[M::mem_pestat] mean and std.dev: (769.61, 621.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3997)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 225, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (251.07, 123.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 843)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (337, 934, 1262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3112)
[M::mem_pestat] mean and std.dev: (860.19, 755.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4037)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 299, 548)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1246)
[M::mem_pestat] mean and std.dev: (346.88, 250.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1595)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699716 sequences (100000094 bp) in 2.411 CPU sec, 2.517 real sec...
[M::process] read 698548 sequences (100000122 bp) in 1.987 CPU sec, 1.991 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 282895, 7, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 339, 861)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2185)
[M::mem_pestat] mean and std.dev: (463.91, 326.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2847)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 227, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 675)
[M::mem_pestat] mean and std.dev: (252.46, 124.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 848)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 259, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1021)
[M::mem_pestat] mean and std.dev: (273.71, 133.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1310)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700572 reads in 198.004 CPU sec, 6.416 real sec
[M::mem_process_seqs] Processed 699820 reads in 133.247 CPU sec, 4.347 real sec
sorting block 121, #reads = 1072090 mem = 536877619 peak = 1077325824
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 282426, 36, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 454, 610)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1436)
[M::mem_pestat] mean and std.dev: (434.98, 313.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1849)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 228, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684)
[M::mem_pestat] mean and std.dev: (253.90, 125.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 860)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (339, 737, 1508)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3846)
[M::mem_pestat] mean and std.dev: (925.15, 891.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5015)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 263, 518)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1200)
[M::mem_pestat] mean and std.dev: (355.03, 257.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1541)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698824 sequences (100000078 bp) in 2.513 CPU sec, 2.649 real sec...
[M::process] read 698546 sequences (100000248 bp) in 1.722 CPU sec, 1.718 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 282274, 25, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 332, 586)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1434)
[M::mem_pestat] mean and std.dev: (348.20, 263.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1858)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 230, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (255.82, 125.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (361, 553, 2038)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5392)
[M::mem_pestat] mean and std.dev: (891.04, 907.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7069)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (307, 473, 1138)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2800)
[M::mem_pestat] mean and std.dev: (640.11, 535.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3631)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699716 reads in 201.890 CPU sec, 6.538 real sec
sorting block 122, #reads = 1070741 mem = 536881634 peak = 1077325824
[M::mem_process_seqs] Processed 698548 reads in 135.318 CPU sec, 4.432 real sec
[M::process] read 698332 sequences (100000126 bp) in 2.475 CPU sec, 2.576 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 281880, 30, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 517, 2272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6372)
[M::mem_pestat] mean and std.dev: (1551.19, 1982.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9481)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 229, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (255.01, 125.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 861)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (306, 499, 1484)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3840)
[M::mem_pestat] mean and std.dev: (797.79, 694.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5018)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 334, 725)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1663)
[M::mem_pestat] mean and std.dev: (405.49, 278.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2132)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697928 sequences (100000151 bp) in 1.904 CPU sec, 1.934 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 282269, 22, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (292, 477, 1067)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2617)
[M::mem_pestat] mean and std.dev: (679.47, 523.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3392)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 230, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (255.24, 125.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (117, 333, 847)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2307)
[M::mem_pestat] mean and std.dev: (493.00, 533.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3037)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 324, 547)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1191)
[M::mem_pestat] mean and std.dev: (331.66, 179.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1513)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698824 reads in 200.830 CPU sec, 6.566 real sec
sorting block 123, #reads = 1070894 mem = 536878922 peak = 1077325824
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 282152, 27, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (126, 319, 1201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3351)
[M::mem_pestat] mean and std.dev: (599.42, 677.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4426)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 229, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (254.88, 124.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (412, 1235, 2563)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6865)
[M::mem_pestat] mean and std.dev: (1375.68, 1247.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9016)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 425, 935)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2341)
[M::mem_pestat] mean and std.dev: (632.69, 536.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3044)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697766 sequences (100000064 bp) in 2.012 CPU sec, 2.016 real sec...
[M::mem_process_seqs] Processed 698546 reads in 223.659 CPU sec, 7.165 real sec
[M::mem_process_seqs] Processed 698332 reads in 245.304 CPU sec, 7.906 real sec
sorting block 124, #reads = 1070656 mem = 536880656 peak = 1077731328
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 281981, 32, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 322, 844)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2148)
[M::mem_pestat] mean and std.dev: (471.80, 380.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2800)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 231, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (256.79, 125.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 1185, 2205)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6243)
[M::mem_pestat] mean and std.dev: (1553.97, 1582.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8262)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 429, 1339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3617)
[M::mem_pestat] mean and std.dev: (739.86, 732.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4756)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697594 sequences (100000147 bp) in 2.682 CPU sec, 2.848 real sec...
[M::process] read 697470 sequences (100000240 bp) in 1.513 CPU sec, 1.518 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 281986, 39, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 315, 1971)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5517)
[M::mem_pestat] mean and std.dev: (925.27, 1069.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7290)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 232, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (257.14, 125.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 867)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (20, 294, 1544)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4592)
[M::mem_pestat] mean and std.dev: (595.46, 746.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6116)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 363, 618)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1464)
[M::mem_pestat] mean and std.dev: (389.14, 289.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1887)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697928 reads in 196.970 CPU sec, 6.326 real sec
sorting block 125, #reads = 1068884 mem = 536881804 peak = 1077731328
[M::mem_process_seqs] Processed 697766 reads in 132.601 CPU sec, 4.336 real sec
sorting block 126, #reads = 1071417 mem = 536880073 peak = 1077731328
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 281889, 33, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (277, 617, 1755)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4711)
[M::mem_pestat] mean and std.dev: (920.14, 849.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6189)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 232, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (257.49, 126.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 867)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 645, 1716)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4802)
[M::mem_pestat] mean and std.dev: (957.94, 998.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6345)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 258, 529)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1223)
[M::mem_pestat] mean and std.dev: (354.14, 255.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1570)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697878 sequences (100000113 bp) in 2.314 CPU sec, 2.448 real sec...
[M::process] read 697804 sequences (100000098 bp) in 1.858 CPU sec, 1.870 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 282181, 30, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 245, 1625)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4503)
[M::mem_pestat] mean and std.dev: (682.31, 804.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5942)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 232, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (257.95, 126.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 528, 1302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3446)
[M::mem_pestat] mean and std.dev: (764.48, 600.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4518)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 286, 993)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2591)
[M::mem_pestat] mean and std.dev: (553.70, 608.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3390)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697594 reads in 193.983 CPU sec, 6.278 real sec
[M::mem_process_seqs] Processed 697470 reads in 129.570 CPU sec, 4.232 real sec
sorting block 127, #reads = 1070238 mem = 536885027 peak = 1077731328
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 281891, 42, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 215, 475)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1095)
[M::mem_pestat] mean and std.dev: (305.73, 223.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1405)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 232, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (257.71, 126.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 867)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (363, 882, 1949)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5121)
[M::mem_pestat] mean and std.dev: (1011.82, 806.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6707)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 331, 1119)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2873)
[M::mem_pestat] mean and std.dev: (589.00, 512.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3750)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697070 sequences (100000012 bp) in 2.467 CPU sec, 2.555 real sec...
[M::process] read 696912 sequences (100000235 bp) in 1.915 CPU sec, 1.919 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 282284, 17, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 344, 586)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1346)
[M::mem_pestat] mean and std.dev: (411.73, 295.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1726)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 231, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (257.28, 126.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 863)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (267, 467, 1776)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4794)
[M::mem_pestat] mean and std.dev: (726.38, 709.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6303)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 425, 907)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2259)
[M::mem_pestat] mean and std.dev: (544.04, 440.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2935)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697878 reads in 192.137 CPU sec, 6.212 real sec
[M::mem_process_seqs] Processed 697804 reads in 127.927 CPU sec, 4.080 real sec
sorting block 128, #reads = 1070453 mem = 536884047 peak = 1077731328
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 281957, 36, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 425, 1033)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2623)
[M::mem_pestat] mean and std.dev: (588.92, 462.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3418)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 233, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697)
[M::mem_pestat] mean and std.dev: (259.39, 127.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 876)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (389, 873, 1646)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4160)
[M::mem_pestat] mean and std.dev: (1086.03, 981.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5417)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 403, 948)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2352)
[M::mem_pestat] mean and std.dev: (506.88, 374.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3054)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696932 sequences (100000284 bp) in 2.276 CPU sec, 2.379 real sec...
[M::process] read 697298 sequences (100000006 bp) in 1.624 CPU sec, 1.629 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 282487, 22, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 225, 800)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2044)
[M::mem_pestat] mean and std.dev: (364.97, 360.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2666)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 233, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697)
[M::mem_pestat] mean and std.dev: (259.93, 128.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 876)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 244, 583)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1381)
[M::mem_pestat] mean and std.dev: (318.35, 256.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1780)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 266, 765)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1869)
[M::mem_pestat] mean and std.dev: (446.69, 393.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2421)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697070 reads in 197.570 CPU sec, 6.426 real sec
sorting block 129, #reads = 1071088 mem = 536881849 peak = 1077731328
[M::mem_process_seqs] Processed 696912 reads in 130.133 CPU sec, 4.262 real sec
sorting block 130, #reads = 1070131 mem = 536884780 peak = 1098514432
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 281379, 24, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (274, 404, 1392)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3628)
[M::mem_pestat] mean and std.dev: (741.49, 747.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4746)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 234, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (260.08, 128.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 880)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 616, 1015)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2645)
[M::mem_pestat] mean and std.dev: (522.33, 379.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3460)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 215, 416)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 924)
[M::mem_pestat] mean and std.dev: (252.27, 164.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1178)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700636 sequences (100000055 bp) in 2.771 CPU sec, 2.894 real sec...
[M::process] read 705152 sequences (100000241 bp) in 1.884 CPU sec, 1.890 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 281133, 25, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 295, 1089)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2821)
[M::mem_pestat] mean and std.dev: (466.96, 499.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3687)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 232, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (258.51, 127.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (360, 940, 1392)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3456)
[M::mem_pestat] mean and std.dev: (883.48, 650.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4488)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 422, 900)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2330)
[M::mem_pestat] mean and std.dev: (579.29, 591.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3045)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696932 reads in 205.762 CPU sec, 6.640 real sec
[M::mem_process_seqs] Processed 697298 reads in 141.267 CPU sec, 4.495 real sec
sorting block 131, #reads = 1068374 mem = 536880263 peak = 1098514432
[M::process] read 703926 sequences (100000090 bp) in 2.551 CPU sec, 2.645 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 282077, 18, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 420, 789)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1961)
[M::mem_pestat] mean and std.dev: (460.33, 381.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2547)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 223, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (248.80, 122.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 830)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (407, 751, 3463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9575)
[M::mem_pestat] mean and std.dev: (1641.44, 1819.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12631)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (272, 423, 1515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4001)
[M::mem_pestat] mean and std.dev: (1057.63, 1167.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5727)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702800 sequences (100000130 bp) in 1.898 CPU sec, 1.906 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 284637, 18, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 559, 1314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3618)
[M::mem_pestat] mean and std.dev: (593.76, 552.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4770)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 213, 308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 626)
[M::mem_pestat] mean and std.dev: (237.82, 115.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 785)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (608, 962, 1219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2441)
[M::mem_pestat] mean and std.dev: (835.19, 485.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3052)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 279, 1045)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2621)
[M::mem_pestat] mean and std.dev: (646.51, 710.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3487)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 284433, 29, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 242, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1078)
[M::mem_pestat] mean and std.dev: (267.49, 190.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1391)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 216, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 636)
[M::mem_pestat] mean and std.dev: (240.55, 117.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 798)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (381, 559, 1923)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5007)
[M::mem_pestat] mean and std.dev: (939.00, 913.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6549)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 311, 434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 838)
[M::mem_pestat] mean and std.dev: (311.46, 113.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1040)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700636 reads in 285.019 CPU sec, 9.110 real sec
sorting block 132, #reads = 1060724 mem = 536880818 peak = 1098514432
[M::mem_process_seqs] Processed 705152 reads in 199.252 CPU sec, 6.389 real sec
[M::mem_process_seqs] Processed 703926 reads in 219.348 CPU sec, 7.044 real sec
[M::process] read 702130 sequences (100000276 bp) in 2.601 CPU sec, 2.728 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 283595, 23, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (267, 335, 720)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1626)
[M::mem_pestat] mean and std.dev: (425.06, 306.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2079)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 219, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 647)
[M::mem_pestat] mean and std.dev: (244.08, 118.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 812)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (89, 270, 1666)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4820)
[M::mem_pestat] mean and std.dev: (911.65, 1095.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6397)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 336, 810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1934)
[M::mem_pestat] mean and std.dev: (438.82, 286.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2496)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 133, #reads = 1071225 mem = 536884366 peak = 1098514432
[M::process] read 701750 sequences (100000030 bp) in 1.970 CPU sec, 2.064 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 284244, 41, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 246, 3486)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10154)
[M::mem_pestat] mean and std.dev: (1195.42, 1558.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13488)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 222, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 654)
[M::mem_pestat] mean and std.dev: (245.93, 119.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 821)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (586, 1235, 3210)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8458)
[M::mem_pestat] mean and std.dev: (1558.76, 1514.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11082)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 214, 1151)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3135)
[M::mem_pestat] mean and std.dev: (659.07, 792.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4127)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702800 reads in 169.799 CPU sec, 5.431 real sec
[M::mem_process_seqs] Processed 702130 reads in 119.972 CPU sec, 3.789 real sec
[M::process] read 702064 sequences (100000299 bp) in 1.952 CPU sec, 2.002 real sec...
sorting block 134, #reads = 1075207 mem = 536880341 peak = 1098514432
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283681, 23, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 523, 1414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3900)
[M::mem_pestat] mean and std.dev: (778.11, 804.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5143)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 222, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 657)
[M::mem_pestat] mean and std.dev: (246.94, 120.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 825)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (385, 823, 2381)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6373)
[M::mem_pestat] mean and std.dev: (1262.24, 1332.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8369)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 279, 741)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1847)
[M::mem_pestat] mean and std.dev: (342.46, 263.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2400)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701142 sequences (100000208 bp) in 2.529 CPU sec, 2.620 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 283913, 16, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 283, 815)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2031)
[M::mem_pestat] mean and std.dev: (482.17, 408.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2639)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 221, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 654)
[M::mem_pestat] mean and std.dev: (245.96, 119.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 821)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (533, 662, 2044)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5066)
[M::mem_pestat] mean and std.dev: (939.13, 786.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6577)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (266, 674, 1291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3341)
[M::mem_pestat] mean and std.dev: (810.49, 694.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4366)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701096 sequences (100000124 bp) in 1.907 CPU sec, 1.909 real sec...
[M::mem_process_seqs] Processed 701750 reads in 183.091 CPU sec, 5.825 real sec
sorting block 135, #reads = 1075847 mem = 536879602 peak = 1098514432
[M::mem_process_seqs] Processed 702064 reads in 124.301 CPU sec, 3.941 real sec
sorting block 136, #reads = 1075043 mem = 536885407 peak = 1098514432
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 283717, 21, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (278, 489, 617)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1295)
[M::mem_pestat] mean and std.dev: (443.64, 214.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1634)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 223, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (248.52, 121.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (279, 446, 1588)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4206)
[M::mem_pestat] mean and std.dev: (898.90, 967.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5515)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 327, 813)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2065)
[M::mem_pestat] mean and std.dev: (450.95, 357.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2691)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700174 sequences (100000025 bp) in 2.334 CPU sec, 2.426 real sec...
[M::process] read 700460 sequences (100000029 bp) in 1.630 CPU sec, 1.628 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 283640, 25, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 421, 1326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3642)
[M::mem_pestat] mean and std.dev: (735.12, 699.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4800)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 223, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (248.62, 121.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 593, 1923)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5415)
[M::mem_pestat] mean and std.dev: (958.60, 1092.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7161)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (333, 528, 806)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1752)
[M::mem_pestat] mean and std.dev: (529.88, 314.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2225)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701142 reads in 186.045 CPU sec, 5.966 real sec
[M::mem_process_seqs] Processed 701096 reads in 123.216 CPU sec, 4.025 real sec
sorting block 137, #reads = 1074180 mem = 536889016 peak = 1098514432
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 283503, 16, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 431, 1307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3515)
[M::mem_pestat] mean and std.dev: (830.03, 837.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4619)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 226, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (251.45, 123.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 847)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (343, 823, 1883)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4963)
[M::mem_pestat] mean and std.dev: (1003.00, 928.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6503)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 445, 875)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2147)
[M::mem_pestat] mean and std.dev: (621.63, 578.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2937)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700416 sequences (100000291 bp) in 2.399 CPU sec, 2.473 real sec...
[M::process] read 700078 sequences (100000164 bp) in 1.969 CPU sec, 1.972 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 283638, 25, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 237, 804)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2020)
[M::mem_pestat] mean and std.dev: (433.73, 370.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2628)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 225, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (251.01, 123.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 843)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (497, 580, 1050)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2156)
[M::mem_pestat] mean and std.dev: (583.95, 327.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2709)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 409, 1326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3612)
[M::mem_pestat] mean and std.dev: (712.56, 746.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4755)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700174 reads in 182.909 CPU sec, 5.914 real sec
[M::mem_process_seqs] Processed 700460 reads in 121.841 CPU sec, 3.867 real sec
sorting block 138, #reads = 1075022 mem = 536879073 peak = 1098514432
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 283369, 27, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 383, 1598)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4432)
[M::mem_pestat] mean and std.dev: (730.89, 737.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5849)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 225, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (251.40, 124.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 847)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (483, 983, 1544)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3666)
[M::mem_pestat] mean and std.dev: (929.36, 623.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4727)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 563, 1084)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2778)
[M::mem_pestat] mean and std.dev: (535.13, 448.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3625)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700274 sequences (100000281 bp) in 2.425 CPU sec, 2.496 real sec...
[M::process] read 700162 sequences (100000055 bp) in 1.840 CPU sec, 1.831 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 283332, 28, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 444, 960)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2514)
[M::mem_pestat] mean and std.dev: (616.97, 568.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3291)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 225, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (251.53, 123.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 847)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (294, 802, 1718)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4566)
[M::mem_pestat] mean and std.dev: (1137.86, 1162.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5990)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 504, 1008)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2572)
[M::mem_pestat] mean and std.dev: (598.12, 526.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3354)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700416 reads in 192.332 CPU sec, 6.201 real sec
sorting block 139, #reads = 1073756 mem = 536877108 peak = 1098514432
[M::mem_process_seqs] Processed 700078 reads in 129.027 CPU sec, 4.223 real sec
sorting block 140, #reads = 1072468 mem = 536879782 peak = 1098514432
[M::process] read 699854 sequences (100000209 bp) in 2.419 CPU sec, 2.483 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 283264, 11, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 383, 805)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1989)
[M::mem_pestat] mean and std.dev: (449.74, 416.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2581)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 226, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (251.52, 123.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 847)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (517, 864, 1847)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4507)
[M::mem_pestat] mean and std.dev: (1218.45, 993.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5837)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 377, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1022)
[M::mem_pestat] mean and std.dev: (312.95, 145.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1297)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699476 sequences (100000286 bp) in 1.820 CPU sec, 1.826 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 282886, 21, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 319, 748)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1932)
[M::mem_pestat] mean and std.dev: (443.36, 415.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2524)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 227, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 681)
[M::mem_pestat] mean and std.dev: (253.53, 124.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 856)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (288, 540, 2216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6072)
[M::mem_pestat] mean and std.dev: (890.06, 731.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8000)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 291, 667)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1661)
[M::mem_pestat] mean and std.dev: (438.64, 320.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2158)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 282975, 19, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 483, 1764)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4832)
[M::mem_pestat] mean and std.dev: (1137.98, 1337.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6487)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 227, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (253.06, 124.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 855)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (387, 618, 817)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1677)
[M::mem_pestat] mean and std.dev: (510.94, 291.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2107)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 272, 493)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1205)
[M::mem_pestat] mean and std.dev: (321.61, 258.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1561)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700274 reads in 260.978 CPU sec, 8.440 real sec
[M::mem_process_seqs] Processed 699854 reads in 193.749 CPU sec, 6.202 real sec
[M::mem_process_seqs] Processed 700162 reads in 215.451 CPU sec, 6.922 real sec
sorting block 141, #reads = 1071630 mem = 536877903 peak = 1098514432
[M::process] read 699350 sequences (100000280 bp) in 2.387 CPU sec, 2.494 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 283250, 18, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 353, 1503)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4021)
[M::mem_pestat] mean and std.dev: (661.06, 697.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5280)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 228, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (254.67, 125.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (260, 717, 1169)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2987)
[M::mem_pestat] mean and std.dev: (719.39, 519.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3896)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 295, 1078)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2946)
[M::mem_pestat] mean and std.dev: (628.23, 680.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3880)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 142, #reads = 1073357 mem = 536882966 peak = 1098514432
[M::process] read 698626 sequences (100000013 bp) in 2.124 CPU sec, 2.192 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 283011, 16, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (257, 686, 1963)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5375)
[M::mem_pestat] mean and std.dev: (1118.74, 1166.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7081)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 228, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (254.32, 124.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 857)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (316, 553, 1970)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5278)
[M::mem_pestat] mean and std.dev: (1083.50, 1199.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6932)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 317, 1180)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3116)
[M::mem_pestat] mean and std.dev: (673.70, 657.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4084)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699476 reads in 180.554 CPU sec, 5.763 real sec
[M::mem_process_seqs] Processed 699350 reads in 122.947 CPU sec, 3.875 real sec
[M::process] read 698100 sequences (100000029 bp) in 2.085 CPU sec, 2.129 real sec...
sorting block 143, #reads = 1073195 mem = 536877143 peak = 1098514432
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 282084, 26, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 258, 768)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1904)
[M::mem_pestat] mean and std.dev: (437.98, 417.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2472)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 231, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (257.00, 126.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (336, 900, 2517)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6879)
[M::mem_pestat] mean and std.dev: (2009.12, 2463.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11863)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 375, 824)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1984)
[M::mem_pestat] mean and std.dev: (454.48, 328.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2564)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698072 sequences (100000008 bp) in 2.642 CPU sec, 2.735 real sec...
[M::process] read 697790 sequences (100000079 bp) in 1.860 CPU sec, 1.855 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 281847, 23, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 388, 893)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2337)
[M::mem_pestat] mean and std.dev: (601.58, 592.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3059)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 232, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (257.83, 126.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (414, 706, 2197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5763)
[M::mem_pestat] mean and std.dev: (1051.18, 1025.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7546)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 652, 1150)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2970)
[M::mem_pestat] mean and std.dev: (813.97, 721.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3880)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698626 reads in 195.663 CPU sec, 6.226 real sec
[M::mem_process_seqs] Processed 698100 reads in 127.795 CPU sec, 4.058 real sec
sorting block 144, #reads = 1070099 mem = 536880227 peak = 1098514432
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 282012, 15, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 389, 670)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1692)
[M::mem_pestat] mean and std.dev: (437.48, 372.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2203)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 231, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (256.82, 125.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 863)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (399, 945, 1322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3168)
[M::mem_pestat] mean and std.dev: (889.29, 734.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4091)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 485, 818)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2064)
[M::mem_pestat] mean and std.dev: (596.14, 496.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2687)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697562 sequences (100000091 bp) in 2.767 CPU sec, 2.912 real sec...
[M::process] read 698044 sequences (100000249 bp) in 1.800 CPU sec, 1.801 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 281439, 38, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 358, 687)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1599)
[M::mem_pestat] mean and std.dev: (319.55, 180.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2055)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 232, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (257.21, 125.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 863)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 696, 1343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3599)
[M::mem_pestat] mean and std.dev: (639.34, 540.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4727)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 375, 1548)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4268)
[M::mem_pestat] mean and std.dev: (719.91, 713.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5628)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698072 reads in 181.542 CPU sec, 5.754 real sec
sorting block 145, #reads = 1069661 mem = 536880731 peak = 1098514432
[M::mem_process_seqs] Processed 697790 reads in 122.286 CPU sec, 3.885 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 281329, 30, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 448, 1438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3880)
[M::mem_pestat] mean and std.dev: (701.12, 781.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5101)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 232, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (257.10, 125.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 863)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 451, 1557)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4381)
[M::mem_pestat] mean and std.dev: (975.23, 1113.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5793)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 528, 1175)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3053)
[M::mem_pestat] mean and std.dev: (600.58, 536.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3992)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697566 sequences (100000207 bp) in 2.176 CPU sec, 2.241 real sec...
[M::process] read 697866 sequences (100000083 bp) in 1.370 CPU sec, 1.372 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281846, 36, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 394, 647)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1461)
[M::mem_pestat] mean and std.dev: (384.63, 244.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1868)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 232, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684)
[M::mem_pestat] mean and std.dev: (256.46, 125.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 859)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (299, 891, 1725)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4577)
[M::mem_pestat] mean and std.dev: (927.97, 791.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6003)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 588, 1469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3949)
[M::mem_pestat] mean and std.dev: (778.66, 757.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5189)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697562 reads in 159.245 CPU sec, 5.278 real sec
sorting block 146, #reads = 1069925 mem = 536879133 peak = 1098514432
[M::mem_process_seqs] Processed 698044 reads in 106.881 CPU sec, 3.409 real sec
sorting block 147, #reads = 1069050 mem = 536880997 peak = 1120083968
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 281938, 21, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (255, 662, 2169)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5997)
[M::mem_pestat] mean and std.dev: (1060.54, 1154.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7911)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 231, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (256.80, 125.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 863)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (370, 544, 1109)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2587)
[M::mem_pestat] mean and std.dev: (638.15, 387.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3326)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 539, 1282)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3480)
[M::mem_pestat] mean and std.dev: (843.61, 781.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4579)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697634 sequences (100000179 bp) in 1.962 CPU sec, 2.039 real sec...
[M::process] read 697282 sequences (100000077 bp) in 1.390 CPU sec, 1.391 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 281985, 37, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (285, 545, 1056)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2598)
[M::mem_pestat] mean and std.dev: (542.77, 418.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3369)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 230, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 686)
[M::mem_pestat] mean and std.dev: (256.15, 125.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 862)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (328, 453, 1982)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5290)
[M::mem_pestat] mean and std.dev: (1260.11, 1561.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7508)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 684, 1106)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2882)
[M::mem_pestat] mean and std.dev: (668.64, 602.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3770)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697566 reads in 160.431 CPU sec, 5.105 real sec
[M::mem_process_seqs] Processed 697866 reads in 109.821 CPU sec, 3.503 real sec
sorting block 148, #reads = 1069075 mem = 536884040 peak = 1120083968
[M::process] read 697494 sequences (100000028 bp) in 2.399 CPU sec, 2.455 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281823, 30, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 378, 1031)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2623)
[M::mem_pestat] mean and std.dev: (693.72, 741.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3660)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 232, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (256.88, 125.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 863)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (127, 511, 1334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3748)
[M::mem_pestat] mean and std.dev: (695.04, 768.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4955)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 518, 835)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2081)
[M::mem_pestat] mean and std.dev: (503.16, 357.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2704)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697634 reads in 113.516 CPU sec, 3.651 real sec
sorting block 149, #reads = 1065073 mem = 536879089 peak = 1120083968
[M::process] read 697430 sequences (100000236 bp) in 2.202 CPU sec, 2.397 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 281845, 28, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 393, 887)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2191)
[M::mem_pestat] mean and std.dev: (510.68, 410.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2843)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 231, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (257.22, 125.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 863)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 1351, 2179)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5995)
[M::mem_pestat] mean and std.dev: (1470.14, 1162.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7903)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 365, 763)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1981)
[M::mem_pestat] mean and std.dev: (453.56, 486.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2590)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698080 sequences (100000117 bp) in 1.780 CPU sec, 1.788 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 281650, 25, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 217, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (213.71, 98.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 232, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (257.29, 125.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 863)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 586, 1022)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2754)
[M::mem_pestat] mean and std.dev: (583.57, 495.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3620)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 345, 684)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1636)
[M::mem_pestat] mean and std.dev: (382.79, 228.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2112)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697282 reads in 193.407 CPU sec, 6.174 real sec
[M::mem_process_seqs] Processed 697494 reads in 217.971 CPU sec, 6.982 real sec
sorting block 150, #reads = 1068633 mem = 536878724 peak = 1120083968
[M::process] read 697702 sequences (100000034 bp) in 2.050 CPU sec, 2.136 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281988, 29, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (341, 387, 1607)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4139)
[M::mem_pestat] mean and std.dev: (944.38, 1020.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5405)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 231, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684)
[M::mem_pestat] mean and std.dev: (256.77, 125.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 859)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 981, 1490)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4096)
[M::mem_pestat] mean and std.dev: (1078.62, 922.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5399)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (265, 446, 1354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3532)
[M::mem_pestat] mean and std.dev: (794.55, 775.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4621)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697430 reads in 99.437 CPU sec, 3.203 real sec
sorting block 151, #reads = 1067935 mem = 536879891 peak = 1120083968
[M::process] read 700156 sequences (100000160 bp) in 1.976 CPU sec, 2.048 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 282159, 44, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 414, 759)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1937)
[M::mem_pestat] mean and std.dev: (467.22, 390.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2526)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 231, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (256.55, 125.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 863)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (349, 616, 2305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6217)
[M::mem_pestat] mean and std.dev: (1311.41, 1493.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8173)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (351, 719, 1161)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2781)
[M::mem_pestat] mean and std.dev: (709.39, 505.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3591)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 709108 sequences (100000237 bp) in 1.499 CPU sec, 1.500 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 281361, 36, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 276, 822)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2090)
[M::mem_pestat] mean and std.dev: (370.62, 410.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2724)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 231, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684)
[M::mem_pestat] mean and std.dev: (256.61, 126.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 859)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (107, 590, 1622)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4652)
[M::mem_pestat] mean and std.dev: (837.22, 945.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6167)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 428, 964)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2388)
[M::mem_pestat] mean and std.dev: (595.59, 464.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3100)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698080 reads in 202.923 CPU sec, 6.503 real sec
[M::mem_process_seqs] Processed 697702 reads in 225.235 CPU sec, 7.264 real sec
sorting block 152, #reads = 1066978 mem = 536881225 peak = 1120083968
[M::process] read 706858 sequences (100000098 bp) in 2.237 CPU sec, 2.330 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 281729, 18, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 338, 1114)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2948)
[M::mem_pestat] mean and std.dev: (628.45, 610.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3865)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 224, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 665)
[M::mem_pestat] mean and std.dev: (250.33, 123.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 835)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (406, 1266, 2435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6493)
[M::mem_pestat] mean and std.dev: (1451.50, 1208.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8522)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 369, 645)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1591)
[M::mem_pestat] mean and std.dev: (359.67, 281.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2064)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705888 sequences (100000265 bp) in 1.500 CPU sec, 1.499 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 285465, 20, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 447, 1060)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2766)
[M::mem_pestat] mean and std.dev: (711.18, 769.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3791)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 208, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 606)
[M::mem_pestat] mean and std.dev: (232.45, 112.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 759)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (67, 405, 1512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4402)
[M::mem_pestat] mean and std.dev: (835.58, 1154.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5847)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 396, 1036)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2658)
[M::mem_pestat] mean and std.dev: (571.25, 478.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3469)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 285889, 16, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 310, 1315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3581)
[M::mem_pestat] mean and std.dev: (718.24, 768.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4714)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 204, 292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 588)
[M::mem_pestat] mean and std.dev: (226.78, 108.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 736)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 881, 1114)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3018)
[M::mem_pestat] mean and std.dev: (773.56, 578.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3970)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 262, 820)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2110)
[M::mem_pestat] mean and std.dev: (423.29, 419.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2755)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700156 reads in 274.179 CPU sec, 8.797 real sec
sorting block 153, #reads = 1058941 mem = 536878766 peak = 1120083968
[M::mem_process_seqs] Processed 706858 reads in 194.815 CPU sec, 6.263 real sec
[M::mem_process_seqs] Processed 709108 reads in 216.445 CPU sec, 6.965 real sec
sorting block 154, #reads = 1067799 mem = 536885897 peak = 1120083968
[M::process] read 704756 sequences (100000074 bp) in 2.597 CPU sec, 2.704 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 284782, 18, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 289, 563)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1419)
[M::mem_pestat] mean and std.dev: (309.12, 236.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1847)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 211, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 619)
[M::mem_pestat] mean and std.dev: (235.39, 113.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 776)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (374, 1255, 1929)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5039)
[M::mem_pestat] mean and std.dev: (1547.78, 1563.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7801)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 378, 849)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2135)
[M::mem_pestat] mean and std.dev: (580.49, 529.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2778)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704076 sequences (100000015 bp) in 2.151 CPU sec, 2.196 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 284726, 19, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 346, 871)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2231)
[M::mem_pestat] mean and std.dev: (497.24, 395.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2911)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 214, 309)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 629)
[M::mem_pestat] mean and std.dev: (238.33, 115.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 789)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (381, 807, 1848)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4782)
[M::mem_pestat] mean and std.dev: (938.69, 808.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6249)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 301, 542)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1238)
[M::mem_pestat] mean and std.dev: (279.74, 145.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1586)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705888 reads in 171.509 CPU sec, 5.459 real sec
[M::mem_process_seqs] Processed 704756 reads in 116.191 CPU sec, 3.649 real sec
sorting block 155, #reads = 1071820 mem = 536882781 peak = 1120083968
[M::process] read 704098 sequences (100000053 bp) in 1.971 CPU sec, 2.023 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 284192, 15, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 368, 1134)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3008)
[M::mem_pestat] mean and std.dev: (724.26, 748.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3945)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 215, 311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 633)
[M::mem_pestat] mean and std.dev: (239.90, 116.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 794)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (495, 922, 1490)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3480)
[M::mem_pestat] mean and std.dev: (874.36, 555.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4475)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 304, 905)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2373)
[M::mem_pestat] mean and std.dev: (462.32, 398.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3107)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705824 sequences (100000113 bp) in 2.027 CPU sec, 2.101 real sec...
[M::process] read 705202 sequences (100000239 bp) in 1.448 CPU sec, 1.445 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 284193, 29, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 1002, 1529)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4127)
[M::mem_pestat] mean and std.dev: (1064.29, 1145.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5648)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 215, 309)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 627)
[M::mem_pestat] mean and std.dev: (239.10, 115.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 786)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (477, 800, 2013)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5085)
[M::mem_pestat] mean and std.dev: (1281.24, 1123.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6621)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 588, 865)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2125)
[M::mem_pestat] mean and std.dev: (517.59, 439.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2755)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704076 reads in 169.510 CPU sec, 5.396 real sec
sorting block 156, #reads = 1071271 mem = 536878362 peak = 1120083968
[M::mem_process_seqs] Processed 704098 reads in 112.283 CPU sec, 3.576 real sec
sorting block 157, #reads = 1072036 mem = 536880288 peak = 1120083968
[M::process] read 703460 sequences (100000003 bp) in 2.455 CPU sec, 2.522 real sec...
[M::process] read 703762 sequences (100000280 bp) in 1.490 CPU sec, 1.486 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 284717, 11, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 412, 616)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1506)
[M::mem_pestat] mean and std.dev: (318.04, 184.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1951)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 212, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 620)
[M::mem_pestat] mean and std.dev: (236.63, 114.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 777)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 369, 1446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3994)
[M::mem_pestat] mean and std.dev: (464.33, 446.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5268)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 238, 492)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1120)
[M::mem_pestat] mean and std.dev: (284.48, 203.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1434)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705202 reads in 97.471 CPU sec, 3.090 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 284743, 20, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 369, 1002)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2646)
[M::mem_pestat] mean and std.dev: (654.47, 716.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3519)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 211, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 619)
[M::mem_pestat] mean and std.dev: (235.48, 113.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 776)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (35, 497, 1561)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4613)
[M::mem_pestat] mean and std.dev: (731.58, 809.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6139)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 316, 807)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1953)
[M::mem_pestat] mean and std.dev: (472.20, 358.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2526)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702672 sequences (100000136 bp) in 1.719 CPU sec, 1.726 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 284748, 27, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (131, 353, 1127)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3119)
[M::mem_pestat] mean and std.dev: (561.55, 579.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4115)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 216, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 636)
[M::mem_pestat] mean and std.dev: (241.05, 117.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 798)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1801, 1907, 3779)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7735)
[M::mem_pestat] mean and std.dev: (2701.56, 1660.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9713)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 338, 1318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3452)
[M::mem_pestat] mean and std.dev: (623.18, 723.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4519)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705824 reads in 270.125 CPU sec, 8.577 real sec
sorting block 158, #reads = 1069625 mem = 536878885 peak = 1120083968
[M::mem_process_seqs] Processed 703460 reads in 132.543 CPU sec, 4.232 real sec
sorting block 159, #reads = 1068752 mem = 536882022 peak = 1120083968
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 283791, 18, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 281, 589)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1343)
[M::mem_pestat] mean and std.dev: (325.26, 179.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1720)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 214, 308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 624)
[M::mem_pestat] mean and std.dev: (238.44, 115.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 782)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 1009, 1376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3760)
[M::mem_pestat] mean and std.dev: (800.41, 600.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4952)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 515, 1350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3630)
[M::mem_pestat] mean and std.dev: (697.87, 786.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4770)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701758 sequences (100000015 bp) in 2.123 CPU sec, 2.241 real sec...
[M::process] read 702158 sequences (100000078 bp) in 1.400 CPU sec, 1.402 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 283761, 34, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 309, 1040)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2764)
[M::mem_pestat] mean and std.dev: (664.22, 748.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3657)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 218, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 644)
[M::mem_pestat] mean and std.dev: (243.80, 119.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 808)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (96, 320, 1110)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3138)
[M::mem_pestat] mean and std.dev: (445.21, 467.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4152)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 373, 989)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2543)
[M::mem_pestat] mean and std.dev: (560.43, 528.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3320)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703762 reads in 171.657 CPU sec, 5.469 real sec
[M::mem_process_seqs] Processed 702672 reads in 115.152 CPU sec, 3.910 real sec
sorting block 160, #reads = 1071390 mem = 536879867 peak = 1120083968
[M::process] read 700910 sequences (100000028 bp) in 2.051 CPU sec, 2.126 real sec...
[M::process] read 700610 sequences (100000228 bp) in 1.467 CPU sec, 1.475 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 283602, 26, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 331, 378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 786)
[M::mem_pestat] mean and std.dev: (277.83, 125.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 990)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 219, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653)
[M::mem_pestat] mean and std.dev: (245.73, 120.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 820)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (542, 830, 1398)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3110)
[M::mem_pestat] mean and std.dev: (1018.64, 757.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4049)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 430, 1145)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2975)
[M::mem_pestat] mean and std.dev: (601.81, 572.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3890)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702158 reads in 96.590 CPU sec, 3.082 real sec
sorting block 161, #reads = 1069518 mem = 536880683 peak = 1120083968
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 283616, 23, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 341, 928)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2346)
[M::mem_pestat] mean and std.dev: (495.77, 438.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3055)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 220, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 654)
[M::mem_pestat] mean and std.dev: (246.36, 120.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 821)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 454, 1037)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2761)
[M::mem_pestat] mean and std.dev: (493.65, 466.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3623)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 423, 875)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2279)
[M::mem_pestat] mean and std.dev: (534.72, 535.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2981)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 283216, 22, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 322, 682)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1642)
[M::mem_pestat] mean and std.dev: (387.90, 308.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2122)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 223, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (249.42, 122.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 435, 771)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2025)
[M::mem_pestat] mean and std.dev: (418.40, 376.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2652)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 325, 771)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1851)
[M::mem_pestat] mean and std.dev: (490.13, 396.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2391)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699650 sequences (100000021 bp) in 1.951 CPU sec, 1.960 real sec...
[M::mem_process_seqs] Processed 701758 reads in 267.951 CPU sec, 8.742 real sec
[M::mem_process_seqs] Processed 700910 reads in 208.832 CPU sec, 6.650 real sec
sorting block 162, #reads = 1071194 mem = 536879701 peak = 1120083968
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 283441, 30, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (268, 516, 909)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2191)
[M::mem_pestat] mean and std.dev: (623.04, 496.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2832)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 224, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667)
[M::mem_pestat] mean and std.dev: (250.13, 123.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 838)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (634, 980, 3230)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8422)
[M::mem_pestat] mean and std.dev: (1322.00, 1217.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11018)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 641, 2388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6758)
[M::mem_pestat] mean and std.dev: (1224.83, 1753.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8943)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698632 sequences (100000134 bp) in 2.408 CPU sec, 2.504 real sec...
[M::process] read 698842 sequences (100000205 bp) in 1.820 CPU sec, 1.817 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 282219, 39, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 351, 808)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2042)
[M::mem_pestat] mean and std.dev: (464.40, 371.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2659)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 227, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 675)
[M::mem_pestat] mean and std.dev: (252.69, 124.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 848)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (508, 890, 1590)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3754)
[M::mem_pestat] mean and std.dev: (1024.68, 701.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4836)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 337, 962)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2496)
[M::mem_pestat] mean and std.dev: (516.13, 531.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3263)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700610 reads in 172.398 CPU sec, 5.473 real sec
sorting block 163, #reads = 1069527 mem = 536878341 peak = 1120083968
[M::mem_process_seqs] Processed 699650 reads in 113.228 CPU sec, 3.827 real sec
[M::process] read 698734 sequences (100000121 bp) in 2.026 CPU sec, 2.111 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 281743, 26, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 265, 680)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1698)
[M::mem_pestat] mean and std.dev: (318.33, 255.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2207)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 227, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 676)
[M::mem_pestat] mean and std.dev: (253.40, 123.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 849)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 469, 1169)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3107)
[M::mem_pestat] mean and std.dev: (580.74, 656.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4076)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 367, 887)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2299)
[M::mem_pestat] mean and std.dev: (445.67, 421.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3005)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698202 sequences (100000259 bp) in 1.370 CPU sec, 1.371 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 282277, 33, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 311, 1106)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2894)
[M::mem_pestat] mean and std.dev: (599.31, 505.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3788)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 229, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (255.02, 125.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 857)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (421, 1019, 4655)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13123)
[M::mem_pestat] mean and std.dev: (1899.82, 1859.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17357)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 394, 1071)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2797)
[M::mem_pestat] mean and std.dev: (589.60, 589.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3660)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 281775, 25, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 228, 1130)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3086)
[M::mem_pestat] mean and std.dev: (496.81, 601.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4064)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 229, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (254.68, 124.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 857)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 544, 1466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4062)
[M::mem_pestat] mean and std.dev: (717.04, 652.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5360)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 357, 627)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1475)
[M::mem_pestat] mean and std.dev: (430.67, 309.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1899)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698632 reads in 233.919 CPU sec, 7.700 real sec
sorting block 164, #reads = 1067602 mem = 536879693 peak = 1120083968
[M::mem_process_seqs] Processed 698842 reads in 173.715 CPU sec, 5.572 real sec
[M::mem_process_seqs] Processed 698734 reads in 194.189 CPU sec, 6.248 real sec
sorting block 165, #reads = 1067572 mem = 536881260 peak = 1120083968
[M::process] read 698378 sequences (100000200 bp) in 2.486 CPU sec, 2.578 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 281819, 33, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 428, 2089)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5979)
[M::mem_pestat] mean and std.dev: (912.52, 976.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7924)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 229, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 677)
[M::mem_pestat] mean and std.dev: (254.63, 124.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 850)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (288, 657, 2403)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6633)
[M::mem_pestat] mean and std.dev: (1017.38, 923.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8748)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 366, 565)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1299)
[M::mem_pestat] mean and std.dev: (346.90, 200.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1666)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697972 sequences (100000191 bp) in 2.074 CPU sec, 2.096 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 281920, 14, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (261, 432, 1310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3408)
[M::mem_pestat] mean and std.dev: (663.93, 582.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4457)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 230, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (254.90, 124.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (268, 794, 1276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3292)
[M::mem_pestat] mean and std.dev: (927.00, 847.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4317)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (263, 452, 1870)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5084)
[M::mem_pestat] mean and std.dev: (955.45, 1009.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6691)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698202 reads in 156.476 CPU sec, 4.983 real sec
sorting block 166, #reads = 1068403 mem = 536880195 peak = 1120083968
[M::mem_process_seqs] Processed 698378 reads in 104.952 CPU sec, 3.309 real sec
[M::process] read 697446 sequences (100000124 bp) in 2.219 CPU sec, 2.292 real sec...
sorting block 167, #reads = 1070414 mem = 536876976 peak = 1120083968
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 282105, 29, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 325, 658)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1578)
[M::mem_pestat] mean and std.dev: (328.97, 251.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2038)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 232, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (257.06, 125.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 863)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (510, 647, 1404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3192)
[M::mem_pestat] mean and std.dev: (664.26, 456.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4086)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 323, 502)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1040)
[M::mem_pestat] mean and std.dev: (321.31, 161.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1309)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696998 sequences (100000290 bp) in 1.837 CPU sec, 1.886 real sec...
[M::process] read 696946 sequences (100000269 bp) in 1.280 CPU sec, 1.273 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 282097, 36, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 297, 584)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1290)
[M::mem_pestat] mean and std.dev: (367.38, 252.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1643)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 232, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684)
[M::mem_pestat] mean and std.dev: (256.95, 125.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 859)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (388, 1279, 3381)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9367)
[M::mem_pestat] mean and std.dev: (1970.58, 1966.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12360)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 312, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 959)
[M::mem_pestat] mean and std.dev: (308.08, 165.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1218)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697972 reads in 152.994 CPU sec, 4.855 real sec
[M::mem_process_seqs] Processed 697446 reads in 103.010 CPU sec, 3.271 real sec
sorting block 168, #reads = 1070478 mem = 536885439 peak = 1120083968
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 281396, 32, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (287, 443, 827)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1907)
[M::mem_pestat] mean and std.dev: (492.85, 369.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2447)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 233, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (257.86, 125.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (492, 1049, 1886)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4674)
[M::mem_pestat] mean and std.dev: (1084.84, 775.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6068)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (283, 547, 728)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1618)
[M::mem_pestat] mean and std.dev: (485.82, 314.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2063)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696918 sequences (100000043 bp) in 2.285 CPU sec, 2.355 real sec...
[M::process] read 696376 sequences (100000136 bp) in 1.510 CPU sec, 1.508 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (81, 281813, 32, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (267, 402, 770)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1776)
[M::mem_pestat] mean and std.dev: (412.99, 289.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2279)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 234, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (258.30, 125.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (424, 1167, 2602)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6958)
[M::mem_pestat] mean and std.dev: (1624.88, 1451.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9136)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 367, 769)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1949)
[M::mem_pestat] mean and std.dev: (415.78, 333.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2539)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696998 reads in 150.083 CPU sec, 4.753 real sec
[M::mem_process_seqs] Processed 696946 reads in 99.181 CPU sec, 3.149 real sec
sorting block 169, #reads = 1071021 mem = 536877912 peak = 1120083968
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 281709, 30, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 623, 1448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3880)
[M::mem_pestat] mean and std.dev: (670.40, 714.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5096)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 234, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (258.99, 126.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 865)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (336, 914, 1620)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4188)
[M::mem_pestat] mean and std.dev: (968.07, 765.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5472)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (271, 616, 1313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3397)
[M::mem_pestat] mean and std.dev: (703.52, 680.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4439)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696600 sequences (100000070 bp) in 2.096 CPU sec, 2.160 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 281814, 33, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 275, 658)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1596)
[M::mem_pestat] mean and std.dev: (381.32, 298.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2065)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 236, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (260.75, 126.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 877)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (106, 436, 1402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3994)
[M::mem_pestat] mean and std.dev: (678.26, 799.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5290)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 353, 1773)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4887)
[M::mem_pestat] mean and std.dev: (812.24, 974.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6444)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696610 sequences (100000293 bp) in 1.740 CPU sec, 1.738 real sec...
[M::mem_process_seqs] Processed 696918 reads in 148.317 CPU sec, 4.697 real sec
sorting block 170, #reads = 1070365 mem = 536877874 peak = 1120083968
[M::mem_process_seqs] Processed 696376 reads in 98.269 CPU sec, 3.110 real sec
sorting block 171, #reads = 1071045 mem = 536878370 peak = 1120083968
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 281344, 31, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 534, 1758)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4818)
[M::mem_pestat] mean and std.dev: (755.50, 728.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6348)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 235, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (260.18, 127.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 873)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (516, 984, 2095)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5253)
[M::mem_pestat] mean and std.dev: (1141.72, 916.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6832)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 629, 939)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2493)
[M::mem_pestat] mean and std.dev: (696.03, 608.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3270)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696776 sequences (100000191 bp) in 2.282 CPU sec, 2.342 real sec...
[M::process] read 232220 sequences (33220811 bp) in 0.660 CPU sec, 0.660 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281520, 32, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 694, 1969)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5621)
[M::mem_pestat] mean and std.dev: (990.08, 944.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7447)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 235, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (260.42, 127.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 877)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 523, 2644)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7614)
[M::mem_pestat] mean and std.dev: (1015.47, 1060.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10099)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 342, 793)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1891)
[M::mem_pestat] mean and std.dev: (435.43, 313.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2440)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696600 reads in 148.427 CPU sec, 4.737 real sec
[M::mem_process_seqs] Processed 696610 reads in 99.079 CPU sec, 3.163 real sec
sorting block 172, #reads = 1070680 mem = 536881571 peak = 1120083968
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281906, 22, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (281, 406, 827)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1919)
[M::mem_pestat] mean and std.dev: (461.42, 341.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2465)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 234, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (260.34, 128.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 880)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 595, 708)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1634)
[M::mem_pestat] mean and std.dev: (558.62, 411.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2205)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 326, 1272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3458)
[M::mem_pestat] mean and std.dev: (592.12, 577.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4551)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 93556, 14, 10)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 352, 478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1058)
[M::mem_pestat] mean and std.dev: (318.42, 154.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1348)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 228, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 673)
[M::mem_pestat] mean and std.dev: (252.94, 122.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 845)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (393, 1300, 2191)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5787)
[M::mem_pestat] mean and std.dev: (1319.36, 1101.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7585)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (302, 1361, 3807)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10817)
[M::mem_pestat] mean and std.dev: (2143.60, 2521.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14322)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696776 reads in 107.144 CPU sec, 3.472 real sec
[M::mem_process_seqs] Processed 232220 reads in 49.220 CPU sec, 1.589 real sec
sorting block 173, #reads = 1070203 mem = 536878172 peak = 1120083968
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 185366908
overall: 70647308288 mem 29183.134 user 528.465 sys 970.667 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1029_HTI-T1-TDNA-1_A23MHWWLT4_1.L002\tPU:L002\tSM:1029_HTI-T1-TDNA-1_A23MHWWLT4_1\tLB:1029_HTI-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1029_HTI-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1029_HTI-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 970.707 sec; CPU: 29711.601 sec
sorting block 174, #reads = 297180 mem = 150358645 peak = 1120083968
uniq header count 1
merging 175 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31 max 192
algo: util-sort
license: sentieon:util=1
output file size: 10132685714
output reads: 186833053
bam_mem_sort: 175 calls 102.380 user 2.693 sys 107.502 real
bam_write: 175 calls 84.886 user 5.744 sys 154.955 real
execute: 1 calls 48.745 user 1.342 sys 1025.509 real
merge_files: 1 calls 48.728 user 1.307 sys 54.394 real
parse_chunk: 2789 calls 123.668 user 29.802 sys 181.346 real
read_chunk: 7545 calls 58.353 user 46.256 sys 926.191 real
sort_block: 1 calls 41.578 user 45.794 sys 901.795 real
write_chunk: 4754 calls 48.348 user 0.953 sys 53.413 real
overall: 3824173056 mem 2246.060 user 108.814 sys 1025.533 real
ls: cannot access '*.cram': No such file or directory