File Info

Filename
.command.log
Full Path
s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/dc/d14dc0961fa95808e3b6d5ef6af708/.command.log
Size
221.1 KB
Task
DAQ:SENTIEON_BWAMEM (1136_3WJ-T1-TDNA-1_A23MHWWLT4_1;L005;0001)
Attempt

Content

View in new tab 
  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/dc/d14dc0961fa95808e3b6d5ef6af708/.command.sh
  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/BWAIndex
  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta.fai
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/a6/029b449bda880bb0b609bae505009e/1136_3WJ-T1-TDNA-1_A23MHWWLT4_1/1136_3WJ-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/a6/029b449bda880bb0b609bae505009e/1136_3WJ-T1-TDNA-1_A23MHWWLT4_1/1136_3WJ-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/dc/d14dc0961fa95808e3b6d5ef6af708/.command.run
==> STAGING COMPLETE (7 inputs)

This software is licensed to bgold@natera.com by Sentieon Inc.
cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1136_3WJ-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 1400.923 CPU sec, 50.768 real sec
[M::process] read 713196 sequences (100000254 bp) in 1.138 CPU sec, 1.145 real sec...
[M::process] read 711412 sequences (100000241 bp) in 1.331 CPU sec, 1.354 real sec...
[M::process] read 710628 sequences (100000033 bp) in 1.346 CPU sec, 1.374 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 281864, 46, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 365, 1030)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2686)
[M::mem_pestat] mean and std.dev: (597.83, 581.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3514)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 205, 293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 595)
[M::mem_pestat] mean and std.dev: (226.43, 109.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 746)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (377, 795, 1441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3569)
[M::mem_pestat] mean and std.dev: (901.93, 770.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4633)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 607, 1620)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4396)
[M::mem_pestat] mean and std.dev: (817.03, 782.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5784)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 710224 sequences (100000149 bp) in 1.567 CPU sec, 1.596 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 282646, 56, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 375, 926)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2346)
[M::mem_pestat] mean and std.dev: (484.77, 430.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3056)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 211, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 633)
[M::mem_pestat] mean and std.dev: (235.17, 116.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 796)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 528, 2121)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5943)
[M::mem_pestat] mean and std.dev: (1154.70, 1515.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7854)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 552, 1025)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2691)
[M::mem_pestat] mean and std.dev: (560.63, 465.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3524)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 282636, 44, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 412, 700)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1668)
[M::mem_pestat] mean and std.dev: (415.60, 272.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2152)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 209, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 615)
[M::mem_pestat] mean and std.dev: (231.43, 113.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 772)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (388, 539, 1414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3466)
[M::mem_pestat] mean and std.dev: (679.67, 550.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4492)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (266, 402, 915)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2213)
[M::mem_pestat] mean and std.dev: (533.59, 460.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2862)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 713196 reads in 275.118 CPU sec, 8.865 real sec
[M::mem_process_seqs] Processed 710628 reads in 211.361 CPU sec, 6.856 real sec
sorting block 0, #reads = 1072577 mem = 536884516 peak = 590307328
[M::mem_process_seqs] Processed 711412 reads in 239.837 CPU sec, 7.766 real sec
[M::process] read 708820 sequences (100000081 bp) in 2.107 CPU sec, 2.226 real sec...
sorting block 1, #reads = 1072627 mem = 536879247 peak = 822079488
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 282781, 40, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (273, 528, 1394)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3636)
[M::mem_pestat] mean and std.dev: (803.09, 691.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4757)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 212, 309)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 637)
[M::mem_pestat] mean and std.dev: (236.30, 116.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 801)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 335, 849)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2005)
[M::mem_pestat] mean and std.dev: (625.83, 546.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2813)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 446, 1377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3673)
[M::mem_pestat] mean and std.dev: (658.12, 609.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4821)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708106 sequences (100000176 bp) in 1.716 CPU sec, 1.735 real sec...
[M::process] read 707686 sequences (100000269 bp) in 1.350 CPU sec, 1.353 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 282465, 36, 81)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 289, 1177)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3157)
[M::mem_pestat] mean and std.dev: (499.52, 541.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4147)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 215, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 647)
[M::mem_pestat] mean and std.dev: (239.43, 118.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 814)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (347, 495, 1787)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4667)
[M::mem_pestat] mean and std.dev: (753.66, 717.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6107)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 366, 1156)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3028)
[M::mem_pestat] mean and std.dev: (624.36, 647.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3964)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 710224 reads in 188.222 CPU sec, 5.975 real sec
[M::mem_process_seqs] Processed 708820 reads in 129.177 CPU sec, 4.123 real sec
sorting block 2, #reads = 1072086 mem = 536883953 peak = 822079488
[M::process] read 707100 sequences (100000186 bp) in 2.070 CPU sec, 2.155 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 281734, 44, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 429, 1681)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4549)
[M::mem_pestat] mean and std.dev: (642.80, 665.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5983)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 218, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 658)
[M::mem_pestat] mean and std.dev: (242.54, 120.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 828)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (276, 1287, 1785)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4803)
[M::mem_pestat] mean and std.dev: (1308.16, 1065.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6312)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 409, 640)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1432)
[M::mem_pestat] mean and std.dev: (430.80, 297.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1828)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706748 sequences (100000299 bp) in 1.445 CPU sec, 1.458 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 281596, 39, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (272, 373, 1105)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2771)
[M::mem_pestat] mean and std.dev: (626.72, 504.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3604)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 217, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 649)
[M::mem_pestat] mean and std.dev: (240.91, 119.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 816)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (427, 769, 1345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3181)
[M::mem_pestat] mean and std.dev: (801.71, 624.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4099)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 272, 829)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2061)
[M::mem_pestat] mean and std.dev: (482.64, 429.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2677)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707686 reads in 178.165 CPU sec, 5.667 real sec
sorting block 3, #reads = 1071219 mem = 536889660 peak = 822079488
[M::mem_process_seqs] Processed 708106 reads in 204.737 CPU sec, 6.525 real sec
[M::process] read 705620 sequences (100000030 bp) in 2.031 CPU sec, 2.113 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 282047, 46, 89)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 382, 732)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1752)
[M::mem_pestat] mean and std.dev: (444.66, 386.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2262)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 219, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 662)
[M::mem_pestat] mean and std.dev: (244.06, 121.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 833)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (343, 876, 1325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3289)
[M::mem_pestat] mean and std.dev: (816.12, 653.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4271)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 520, 1392)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3806)
[M::mem_pestat] mean and std.dev: (773.11, 745.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5013)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705002 sequences (100000209 bp) in 1.470 CPU sec, 1.466 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (100, 281419, 51, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 360, 1261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3359)
[M::mem_pestat] mean and std.dev: (638.82, 614.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4408)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 220, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 662)
[M::mem_pestat] mean and std.dev: (244.33, 121.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 833)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (342, 886, 1619)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4173)
[M::mem_pestat] mean and std.dev: (1109.60, 1074.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5450)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 404, 732)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1708)
[M::mem_pestat] mean and std.dev: (418.98, 281.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2196)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707100 reads in 187.463 CPU sec, 5.962 real sec
sorting block 4, #reads = 1072501 mem = 536886609 peak = 822079488
[M::mem_process_seqs] Processed 706748 reads in 216.700 CPU sec, 6.918 real sec
sorting block 5, #reads = 1071402 mem = 536880880 peak = 822968320
[M::process] read 703904 sequences (100000168 bp) in 2.337 CPU sec, 2.402 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 280789, 48, 88)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 513, 763)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1931)
[M::mem_pestat] mean and std.dev: (499.08, 365.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2515)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 222, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 669)
[M::mem_pestat] mean and std.dev: (246.18, 121.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 842)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (129, 864, 1839)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5259)
[M::mem_pestat] mean and std.dev: (942.07, 954.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6969)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (312, 543, 1308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3300)
[M::mem_pestat] mean and std.dev: (709.07, 550.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4296)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704576 sequences (100000111 bp) in 1.603 CPU sec, 1.611 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 280167, 64, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (270, 510, 1372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3576)
[M::mem_pestat] mean and std.dev: (657.10, 608.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4678)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 226, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 669)
[M::mem_pestat] mean and std.dev: (248.51, 121.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 841)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (328, 740, 1710)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4474)
[M::mem_pestat] mean and std.dev: (1080.11, 923.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5856)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 441, 1386)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3734)
[M::mem_pestat] mean and std.dev: (833.63, 919.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4908)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 280343, 47, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (307, 565, 1160)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2866)
[M::mem_pestat] mean and std.dev: (725.17, 653.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3719)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (247.47, 122.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 844)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 542, 1236)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3298)
[M::mem_pestat] mean and std.dev: (601.93, 512.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4329)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 306, 1113)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2865)
[M::mem_pestat] mean and std.dev: (561.88, 492.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3741)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705620 reads in 281.544 CPU sec, 8.989 real sec
[M::mem_process_seqs] Processed 703904 reads in 228.709 CPU sec, 7.342 real sec
[M::mem_process_seqs] Processed 705002 reads in 259.014 CPU sec, 8.308 real sec
sorting block 6, #reads = 1070668 mem = 536879213 peak = 822968320
[M::process] read 704318 sequences (100000064 bp) in 3.062 CPU sec, 3.217 real sec...
sorting block 7, #reads = 1068376 mem = 536878571 peak = 822968320
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 280555, 36, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 641, 1249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3341)
[M::mem_pestat] mean and std.dev: (717.87, 638.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4387)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 225, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (247.51, 121.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 840)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (306, 515, 1370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3498)
[M::mem_pestat] mean and std.dev: (702.33, 755.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4562)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 343, 828)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2104)
[M::mem_pestat] mean and std.dev: (512.32, 469.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2742)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704636 sequences (100000003 bp) in 2.373 CPU sec, 2.405 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 280156, 55, 90)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (341, 607, 1657)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4289)
[M::mem_pestat] mean and std.dev: (962.05, 894.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5605)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 659)
[M::mem_pestat] mean and std.dev: (246.08, 119.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 828)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 514, 1007)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2685)
[M::mem_pestat] mean and std.dev: (584.00, 489.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3524)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 386, 908)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2272)
[M::mem_pestat] mean and std.dev: (535.71, 449.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2954)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704364 sequences (100000007 bp) in 2.110 CPU sec, 2.110 real sec...
[M::mem_process_seqs] Processed 704576 reads in 210.749 CPU sec, 6.664 real sec
[M::mem_process_seqs] Processed 704318 reads in 150.400 CPU sec, 4.742 real sec
sorting block 8, #reads = 1066409 mem = 536881649 peak = 822968320
[M::process] read 704708 sequences (100000144 bp) in 2.952 CPU sec, 3.047 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 280275, 34, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 359, 1298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3500)
[M::mem_pestat] mean and std.dev: (718.01, 797.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4601)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 223, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 656)
[M::mem_pestat] mean and std.dev: (245.07, 118.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 824)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (388, 776, 2762)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7510)
[M::mem_pestat] mean and std.dev: (1693.62, 2076.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9998)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 502, 1009)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2569)
[M::mem_pestat] mean and std.dev: (635.03, 548.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3349)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 710270 sequences (100000122 bp) in 2.190 CPU sec, 2.189 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 279779, 42, 87)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 465, 1245)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3337)
[M::mem_pestat] mean and std.dev: (653.86, 622.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4383)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (247.46, 121.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 840)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 404, 1323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3629)
[M::mem_pestat] mean and std.dev: (899.33, 1005.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4922)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 437, 965)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2431)
[M::mem_pestat] mean and std.dev: (530.36, 417.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3164)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704636 reads in 209.347 CPU sec, 6.637 real sec
sorting block 9, #reads = 1064812 mem = 536879739 peak = 822968320
[M::mem_process_seqs] Processed 704364 reads in 242.581 CPU sec, 7.710 real sec
[M::process] read 710998 sequences (100000269 bp) in 2.587 CPU sec, 2.665 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 280624, 62, 89)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 265, 962)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2596)
[M::mem_pestat] mean and std.dev: (520.05, 562.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3413)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 223, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 665)
[M::mem_pestat] mean and std.dev: (246.85, 121.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 836)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 799, 1406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3866)
[M::mem_pestat] mean and std.dev: (745.27, 731.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5096)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 400, 842)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2076)
[M::mem_pestat] mean and std.dev: (530.49, 437.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2693)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 709588 sequences (100000048 bp) in 2.180 CPU sec, 2.182 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 281559, 41, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 429, 1146)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3076)
[M::mem_pestat] mean and std.dev: (716.07, 705.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4041)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 211, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 628)
[M::mem_pestat] mean and std.dev: (234.64, 115.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 789)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (399, 679, 1677)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4233)
[M::mem_pestat] mean and std.dev: (967.34, 877.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5511)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 503, 1232)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3214)
[M::mem_pestat] mean and std.dev: (714.47, 690.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4205)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704708 reads in 216.640 CPU sec, 6.864 real sec
sorting block 10, #reads = 1065400 mem = 536881824 peak = 822968320
[M::mem_process_seqs] Processed 710270 reads in 252.322 CPU sec, 8.085 real sec
sorting block 11, #reads = 1066214 mem = 536880357 peak = 822968320
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 282226, 29, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 311, 706)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1710)
[M::mem_pestat] mean and std.dev: (454.84, 382.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2212)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 213, 310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 638)
[M::mem_pestat] mean and std.dev: (236.98, 117.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 802)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 654, 2387)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6841)
[M::mem_pestat] mean and std.dev: (1049.74, 1354.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9068)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 410, 1191)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3209)
[M::mem_pestat] mean and std.dev: (550.03, 537.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4218)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 709636 sequences (100000008 bp) in 3.041 CPU sec, 3.143 real sec...
[M::process] read 708756 sequences (100000297 bp) in 2.220 CPU sec, 2.215 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 282350, 65, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 340, 1187)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3097)
[M::mem_pestat] mean and std.dev: (574.47, 524.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4052)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 209, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 618)
[M::mem_pestat] mean and std.dev: (232.48, 114.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 776)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (311, 706, 2235)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6083)
[M::mem_pestat] mean and std.dev: (1258.98, 1380.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8007)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 438, 1790)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4962)
[M::mem_pestat] mean and std.dev: (830.07, 960.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6548)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 709588 reads in 210.440 CPU sec, 6.658 real sec
[M::mem_process_seqs] Processed 710998 reads in 242.441 CPU sec, 7.694 real sec
sorting block 12, #reads = 1072183 mem = 536884641 peak = 822968320
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (87, 282573, 40, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 366, 873)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2197)
[M::mem_pestat] mean and std.dev: (474.78, 424.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2859)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 213, 310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 638)
[M::mem_pestat] mean and std.dev: (237.35, 117.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 802)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (355, 760, 1763)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4579)
[M::mem_pestat] mean and std.dev: (932.34, 824.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5987)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 452, 1095)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2837)
[M::mem_pestat] mean and std.dev: (609.49, 616.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3708)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708586 sequences (100000178 bp) in 3.069 CPU sec, 3.173 real sec...
[M::process] read 707546 sequences (100000169 bp) in 2.269 CPU sec, 2.274 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 282274, 45, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 331, 744)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1838)
[M::mem_pestat] mean and std.dev: (428.21, 358.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2385)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 215, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 645)
[M::mem_pestat] mean and std.dev: (239.34, 118.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 811)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (273, 424, 1149)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2901)
[M::mem_pestat] mean and std.dev: (640.02, 636.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3777)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (265, 435, 1098)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2764)
[M::mem_pestat] mean and std.dev: (617.15, 592.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3597)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 709636 reads in 202.783 CPU sec, 6.406 real sec
sorting block 13, #reads = 1074016 mem = 536878977 peak = 822968320
[M::mem_process_seqs] Processed 708756 reads in 233.340 CPU sec, 7.401 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (84, 282525, 48, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 273, 730)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1876)
[M::mem_pestat] mean and std.dev: (418.86, 389.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2449)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 215, 314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 648)
[M::mem_pestat] mean and std.dev: (239.97, 119.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 815)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (320, 618, 1511)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3893)
[M::mem_pestat] mean and std.dev: (731.12, 697.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5084)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 437, 1092)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2806)
[M::mem_pestat] mean and std.dev: (691.50, 612.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3663)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706964 sequences (100000010 bp) in 3.274 CPU sec, 3.427 real sec...
[M::process] read 706526 sequences (100000271 bp) in 2.210 CPU sec, 2.205 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 281780, 55, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 512, 964)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2530)
[M::mem_pestat] mean and std.dev: (584.90, 495.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3313)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 218, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 650)
[M::mem_pestat] mean and std.dev: (241.91, 119.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 817)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (487, 800, 2193)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5605)
[M::mem_pestat] mean and std.dev: (1358.19, 1273.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7311)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 447, 1008)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2554)
[M::mem_pestat] mean and std.dev: (569.43, 524.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3327)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 708586 reads in 203.733 CPU sec, 6.440 real sec
sorting block 14, #reads = 1072495 mem = 536878942 peak = 822968320
[M::mem_process_seqs] Processed 707546 reads in 233.869 CPU sec, 7.427 real sec
sorting block 15, #reads = 1072684 mem = 536882893 peak = 822968320
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 282170, 46, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 327, 727)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1825)
[M::mem_pestat] mean and std.dev: (449.57, 379.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2374)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 219, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 656)
[M::mem_pestat] mean and std.dev: (242.81, 120.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 825)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 564, 2272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6474)
[M::mem_pestat] mean and std.dev: (1190.02, 1406.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8575)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (270, 473, 1009)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2487)
[M::mem_pestat] mean and std.dev: (560.19, 464.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3226)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706638 sequences (100000224 bp) in 3.104 CPU sec, 3.177 real sec...
[M::process] read 705958 sequences (100000208 bp) in 2.210 CPU sec, 2.217 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (81, 281088, 65, 87)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 379, 978)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2522)
[M::mem_pestat] mean and std.dev: (550.41, 515.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3294)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 220, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 662)
[M::mem_pestat] mean and std.dev: (244.57, 121.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 833)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 555, 1067)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2915)
[M::mem_pestat] mean and std.dev: (609.18, 593.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3839)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (271, 561, 1644)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4390)
[M::mem_pestat] mean and std.dev: (869.49, 844.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5763)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706964 reads in 205.011 CPU sec, 6.480 real sec
[M::mem_process_seqs] Processed 706526 reads in 236.921 CPU sec, 7.517 real sec
sorting block 16, #reads = 1070972 mem = 536879323 peak = 822968320
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (86, 280796, 43, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 246, 827)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2165)
[M::mem_pestat] mean and std.dev: (472.89, 467.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2834)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 221, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 663)
[M::mem_pestat] mean and std.dev: (245.29, 120.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (314, 711, 1273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3191)
[M::mem_pestat] mean and std.dev: (787.62, 651.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4150)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 817, 2260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6384)
[M::mem_pestat] mean and std.dev: (1147.60, 1368.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8446)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705120 sequences (100000190 bp) in 3.031 CPU sec, 3.100 real sec...
[M::process] read 704672 sequences (100000162 bp) in 2.220 CPU sec, 2.217 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (79, 281272, 44, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 488, 1505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4027)
[M::mem_pestat] mean and std.dev: (670.16, 685.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5288)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 220, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 659)
[M::mem_pestat] mean and std.dev: (243.92, 120.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 829)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (64, 325, 1152)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3328)
[M::mem_pestat] mean and std.dev: (675.26, 816.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4416)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 316, 774)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1912)
[M::mem_pestat] mean and std.dev: (431.86, 336.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2481)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705958 reads in 207.111 CPU sec, 6.550 real sec
sorting block 17, #reads = 1069864 mem = 536881839 peak = 822968320
[M::mem_process_seqs] Processed 706638 reads in 239.392 CPU sec, 7.604 real sec
[M::process] read 704994 sequences (100000136 bp) in 2.812 CPU sec, 2.906 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 280621, 56, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (270, 419, 854)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2022)
[M::mem_pestat] mean and std.dev: (561.71, 467.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2606)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 223, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 659)
[M::mem_pestat] mean and std.dev: (245.84, 120.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 828)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (336, 582, 1606)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4146)
[M::mem_pestat] mean and std.dev: (965.65, 862.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5416)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 346, 1306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3468)
[M::mem_pestat] mean and std.dev: (710.58, 675.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4549)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705058 sequences (100000084 bp) in 2.268 CPU sec, 2.267 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (84, 281113, 41, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 473, 1198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3168)
[M::mem_pestat] mean and std.dev: (692.40, 710.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4153)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 223, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 662)
[M::mem_pestat] mean and std.dev: (246.23, 120.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 832)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (277, 603, 2440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6766)
[M::mem_pestat] mean and std.dev: (1216.51, 1374.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8929)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 404, 739)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1705)
[M::mem_pestat] mean and std.dev: (538.72, 426.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2246)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704672 reads in 208.355 CPU sec, 6.591 real sec
sorting block 18, #reads = 1069487 mem = 536877763 peak = 822968320
[M::mem_process_seqs] Processed 705120 reads in 240.558 CPU sec, 7.639 real sec
sorting block 19, #reads = 1068907 mem = 536885673 peak = 822968320
[M::process] read 704670 sequences (100000154 bp) in 2.944 CPU sec, 3.011 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 280891, 55, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (252, 819, 1294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3378)
[M::mem_pestat] mean and std.dev: (936.29, 854.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4420)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 221, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 655)
[M::mem_pestat] mean and std.dev: (244.33, 119.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 823)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 595, 2355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6629)
[M::mem_pestat] mean and std.dev: (1220.94, 1367.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8766)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 413, 1068)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2768)
[M::mem_pestat] mean and std.dev: (674.90, 654.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3618)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704672 sequences (100000170 bp) in 2.246 CPU sec, 2.256 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 280542, 35, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 513, 966)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2478)
[M::mem_pestat] mean and std.dev: (564.62, 471.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3234)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 222, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 655)
[M::mem_pestat] mean and std.dev: (244.36, 119.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 823)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 885, 1829)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5045)
[M::mem_pestat] mean and std.dev: (1115.03, 1043.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6653)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 440, 822)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1990)
[M::mem_pestat] mean and std.dev: (508.99, 399.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2574)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704994 reads in 210.990 CPU sec, 6.674 real sec
[M::mem_process_seqs] Processed 705058 reads in 244.254 CPU sec, 7.752 real sec
sorting block 20, #reads = 1067889 mem = 536889756 peak = 822968320
[M::process] read 706926 sequences (100000007 bp) in 2.537 CPU sec, 2.616 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (87, 280521, 50, 91)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (255, 621, 1071)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2703)
[M::mem_pestat] mean and std.dev: (615.18, 425.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3519)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 222, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 658)
[M::mem_pestat] mean and std.dev: (245.44, 119.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 827)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (317, 635, 1496)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3854)
[M::mem_pestat] mean and std.dev: (828.35, 700.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5033)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 359, 988)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2546)
[M::mem_pestat] mean and std.dev: (546.15, 477.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3325)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 712746 sequences (100000099 bp) in 2.240 CPU sec, 2.238 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 280553, 57, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 378, 1177)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3133)
[M::mem_pestat] mean and std.dev: (651.76, 664.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4111)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 223, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 665)
[M::mem_pestat] mean and std.dev: (247.11, 121.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 836)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 458, 1073)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2851)
[M::mem_pestat] mean and std.dev: (561.94, 577.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3740)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (308, 684, 844)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1916)
[M::mem_pestat] mean and std.dev: (577.02, 360.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2452)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704670 reads in 210.100 CPU sec, 6.652 real sec
sorting block 21, #reads = 1067393 mem = 536881330 peak = 822968320
[M::mem_process_seqs] Processed 704672 reads in 243.335 CPU sec, 7.728 real sec
[M::process] read 709890 sequences (100000088 bp) in 3.071 CPU sec, 3.157 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 282741, 47, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 254, 496)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1172)
[M::mem_pestat] mean and std.dev: (341.13, 259.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1510)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 206, 296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 604)
[M::mem_pestat] mean and std.dev: (228.04, 111.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 758)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (287, 568, 1401)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3629)
[M::mem_pestat] mean and std.dev: (779.89, 708.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4743)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 356, 1354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3576)
[M::mem_pestat] mean and std.dev: (767.38, 791.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4687)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708344 sequences (100000000 bp) in 2.220 CPU sec, 2.213 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 281025, 46, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (336, 641, 1795)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4713)
[M::mem_pestat] mean and std.dev: (967.36, 864.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6172)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 218, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653)
[M::mem_pestat] mean and std.dev: (242.54, 120.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 821)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (502, 1079, 1970)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4906)
[M::mem_pestat] mean and std.dev: (1220.98, 1015.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6374)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 413, 658)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1516)
[M::mem_pestat] mean and std.dev: (442.11, 294.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1945)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 712746 reads in 214.772 CPU sec, 6.800 real sec
sorting block 22, #reads = 1069430 mem = 536886086 peak = 822968320
[M::mem_process_seqs] Processed 706926 reads in 249.424 CPU sec, 7.937 real sec
sorting block 23, #reads = 1069800 mem = 536881655 peak = 850358272
[M::process] read 707970 sequences (100000250 bp) in 2.658 CPU sec, 2.758 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 282309, 41, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 335, 840)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2200)
[M::mem_pestat] mean and std.dev: (462.44, 406.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2880)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 213, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 631)
[M::mem_pestat] mean and std.dev: (235.42, 115.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 793)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (270, 581, 1856)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5028)
[M::mem_pestat] mean and std.dev: (1230.88, 1429.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6949)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 367, 884)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2248)
[M::mem_pestat] mean and std.dev: (500.56, 417.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2930)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707724 sequences (100000281 bp) in 2.210 CPU sec, 2.203 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 282102, 58, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 502, 1465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3997)
[M::mem_pestat] mean and std.dev: (674.24, 702.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5263)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 216, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 642)
[M::mem_pestat] mean and std.dev: (238.97, 117.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 807)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (360, 559, 1377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3411)
[M::mem_pestat] mean and std.dev: (775.04, 641.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4428)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 356, 1125)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2861)
[M::mem_pestat] mean and std.dev: (618.29, 582.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3729)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 709890 reads in 206.862 CPU sec, 6.546 real sec
[M::mem_process_seqs] Processed 708344 reads in 237.300 CPU sec, 7.537 real sec
sorting block 24, #reads = 1072402 mem = 536878345 peak = 850358272
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (81, 281854, 32, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 316, 1149)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3099)
[M::mem_pestat] mean and std.dev: (583.34, 588.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4074)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 217, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 649)
[M::mem_pestat] mean and std.dev: (240.79, 119.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 816)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (307, 691, 1474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3808)
[M::mem_pestat] mean and std.dev: (835.41, 669.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4975)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 394, 892)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2288)
[M::mem_pestat] mean and std.dev: (546.83, 509.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2986)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707472 sequences (100000204 bp) in 2.778 CPU sec, 2.848 real sec...
[M::process] read 706508 sequences (100000067 bp) in 2.190 CPU sec, 2.187 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 281818, 46, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (309, 411, 1139)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2799)
[M::mem_pestat] mean and std.dev: (699.83, 611.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3629)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 217, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 655)
[M::mem_pestat] mean and std.dev: (242.05, 120.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 824)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (100, 310, 842)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2326)
[M::mem_pestat] mean and std.dev: (446.02, 459.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3068)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 383, 1010)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2544)
[M::mem_pestat] mean and std.dev: (534.59, 448.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3311)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707970 reads in 209.208 CPU sec, 6.658 real sec
[M::mem_process_seqs] Processed 707724 reads in 146.934 CPU sec, 4.676 real sec
sorting block 25, #reads = 1070619 mem = 536876690 peak = 850358272
[M::process] read 707296 sequences (100000082 bp) in 2.290 CPU sec, 2.368 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (92, 282163, 29, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 340, 840)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2200)
[M::mem_pestat] mean and std.dev: (455.32, 440.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2880)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 219, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 658)
[M::mem_pestat] mean and std.dev: (243.11, 121.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 828)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 574, 1493)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4137)
[M::mem_pestat] mean and std.dev: (983.89, 1166.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5650)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 416, 757)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1765)
[M::mem_pestat] mean and std.dev: (534.36, 389.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2269)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705588 sequences (100000056 bp) in 2.150 CPU sec, 2.157 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 281911, 47, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 534, 953)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2421)
[M::mem_pestat] mean and std.dev: (642.39, 540.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3155)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 218, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 652)
[M::mem_pestat] mean and std.dev: (242.09, 120.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 820)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (595, 1369, 1767)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4111)
[M::mem_pestat] mean and std.dev: (1128.43, 761.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5283)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 611, 1333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3499)
[M::mem_pestat] mean and std.dev: (744.99, 640.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4582)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (99, 281231, 43, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 409, 1175)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3085)
[M::mem_pestat] mean and std.dev: (677.80, 645.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4040)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 220, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (245.38, 122.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 838)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 712, 1497)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4075)
[M::mem_pestat] mean and std.dev: (763.03, 834.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5364)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 307, 1017)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2687)
[M::mem_pestat] mean and std.dev: (479.37, 463.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3522)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707472 reads in 285.196 CPU sec, 9.099 real sec
sorting block 26, #reads = 1071720 mem = 536877750 peak = 850358272
[M::mem_process_seqs] Processed 707296 reads in 229.257 CPU sec, 7.353 real sec
[M::mem_process_seqs] Processed 706508 reads in 260.991 CPU sec, 8.369 real sec
sorting block 27, #reads = 1070801 mem = 536881949 peak = 878850048
[M::process] read 704608 sequences (100000095 bp) in 2.608 CPU sec, 2.738 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 280788, 50, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 385, 765)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1839)
[M::mem_pestat] mean and std.dev: (392.18, 263.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2376)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 222, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 669)
[M::mem_pestat] mean and std.dev: (246.56, 122.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 842)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 556, 1619)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4427)
[M::mem_pestat] mean and std.dev: (1015.04, 1121.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5831)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 404, 1257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3419)
[M::mem_pestat] mean and std.dev: (689.71, 691.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4500)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703802 sequences (100000055 bp) in 2.465 CPU sec, 2.514 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (85, 280199, 49, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 512, 1588)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4368)
[M::mem_pestat] mean and std.dev: (949.27, 1054.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5758)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 665)
[M::mem_pestat] mean and std.dev: (247.23, 121.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 836)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (323, 536, 1180)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2894)
[M::mem_pestat] mean and std.dev: (620.42, 571.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3751)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 353, 1176)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3060)
[M::mem_pestat] mean and std.dev: (624.54, 574.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4002)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704486 sequences (100000029 bp) in 2.090 CPU sec, 2.086 real sec...
[M::mem_process_seqs] Processed 705588 reads in 204.306 CPU sec, 6.459 real sec
sorting block 28, #reads = 1070890 mem = 536878453 peak = 878850048
[M::mem_process_seqs] Processed 704608 reads in 147.975 CPU sec, 4.671 real sec
sorting block 29, #reads = 1068153 mem = 536879179 peak = 884187136
[M::process] read 705372 sequences (100000160 bp) in 2.690 CPU sec, 2.786 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (94, 279660, 52, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 361, 857)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2231)
[M::mem_pestat] mean and std.dev: (502.22, 461.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2918)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 224, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (247.66, 121.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 837)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (368, 737, 1127)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2645)
[M::mem_pestat] mean and std.dev: (810.14, 651.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3416)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (269, 499, 991)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2435)
[M::mem_pestat] mean and std.dev: (571.47, 490.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3157)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705092 sequences (100000165 bp) in 2.170 CPU sec, 2.167 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 281111, 52, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 362, 1783)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4935)
[M::mem_pestat] mean and std.dev: (954.57, 1108.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6511)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 222, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 659)
[M::mem_pestat] mean and std.dev: (245.66, 120.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 828)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (349, 676, 1032)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2398)
[M::mem_pestat] mean and std.dev: (740.59, 566.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3081)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 280, 1127)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2905)
[M::mem_pestat] mean and std.dev: (581.30, 565.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3794)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703802 reads in 199.672 CPU sec, 6.314 real sec
[M::mem_process_seqs] Processed 704486 reads in 229.677 CPU sec, 7.289 real sec
sorting block 30, #reads = 1067632 mem = 536878419 peak = 884187136
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 280536, 38, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 556, 1354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3656)
[M::mem_pestat] mean and std.dev: (801.06, 869.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4807)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 220, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 651)
[M::mem_pestat] mean and std.dev: (243.33, 119.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 818)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 1001, 1533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4087)
[M::mem_pestat] mean and std.dev: (1024.08, 808.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5364)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 300, 728)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1746)
[M::mem_pestat] mean and std.dev: (406.65, 293.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2255)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704566 sequences (100000141 bp) in 2.652 CPU sec, 2.714 real sec...
[M::process] read 704568 sequences (100000079 bp) in 2.190 CPU sec, 2.186 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 280510, 29, 89)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 334, 631)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1411)
[M::mem_pestat] mean and std.dev: (362.06, 249.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1801)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 222, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (245.24, 120.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 831)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 605, 1627)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4581)
[M::mem_pestat] mean and std.dev: (614.44, 695.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6058)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (265, 471, 1147)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2911)
[M::mem_pestat] mean and std.dev: (662.19, 548.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3793)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705372 reads in 200.408 CPU sec, 6.340 real sec
sorting block 31, #reads = 1067638 mem = 536883289 peak = 884187136
[M::mem_process_seqs] Processed 705092 reads in 146.133 CPU sec, 4.649 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (90, 279950, 36, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 396, 740)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1842)
[M::mem_pestat] mean and std.dev: (496.37, 423.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2393)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 665)
[M::mem_pestat] mean and std.dev: (246.73, 120.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 836)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 1124, 3781)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10815)
[M::mem_pestat] mean and std.dev: (1928.86, 2273.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14332)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 412, 1056)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2702)
[M::mem_pestat] mean and std.dev: (632.88, 636.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3525)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707440 sequences (100000177 bp) in 2.679 CPU sec, 2.739 real sec...
[M::process] read 713180 sequences (100000010 bp) in 2.190 CPU sec, 2.187 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 280991, 41, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 514, 1391)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3773)
[M::mem_pestat] mean and std.dev: (732.78, 692.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4964)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (248.05, 122.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 844)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (273, 910, 1469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3861)
[M::mem_pestat] mean and std.dev: (1030.76, 1024.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5130)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 276, 887)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2235)
[M::mem_pestat] mean and std.dev: (490.81, 459.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2909)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704566 reads in 197.683 CPU sec, 6.250 real sec
sorting block 32, #reads = 1065598 mem = 536878486 peak = 884187136
[M::mem_process_seqs] Processed 704568 reads in 140.670 CPU sec, 4.473 real sec
sorting block 33, #reads = 1066095 mem = 536878384 peak = 890564608
[M::process] read 709424 sequences (100000038 bp) in 2.949 CPU sec, 3.035 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 281084, 45, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 360, 865)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2179)
[M::mem_pestat] mean and std.dev: (509.76, 427.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2836)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 217, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 655)
[M::mem_pestat] mean and std.dev: (242.21, 120.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 824)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 787, 2240)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6302)
[M::mem_pestat] mean and std.dev: (1404.23, 1750.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8404)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 325, 1107)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2909)
[M::mem_pestat] mean and std.dev: (656.66, 697.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3810)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708762 sequences (100000095 bp) in 2.220 CPU sec, 2.214 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 282985, 38, 87)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 484, 1168)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3080)
[M::mem_pestat] mean and std.dev: (693.08, 592.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4036)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 205, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 601)
[M::mem_pestat] mean and std.dev: (227.45, 111.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 754)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 537, 1401)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3925)
[M::mem_pestat] mean and std.dev: (610.31, 695.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5187)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 427, 1216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3162)
[M::mem_pestat] mean and std.dev: (729.01, 687.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4135)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707440 reads in 206.233 CPU sec, 6.521 real sec
[M::process] read 708212 sequences (100000208 bp) in 1.724 CPU sec, 1.726 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (88, 280812, 44, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 382, 900)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2326)
[M::mem_pestat] mean and std.dev: (501.55, 473.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3039)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 213, 308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 632)
[M::mem_pestat] mean and std.dev: (236.37, 116.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 794)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (450, 910, 1081)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2343)
[M::mem_pestat] mean and std.dev: (807.12, 564.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3064)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 379, 822)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1958)
[M::mem_pestat] mean and std.dev: (479.73, 361.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2526)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 709424 reads in 111.030 CPU sec, 3.533 real sec
sorting block 34, #reads = 1065603 mem = 536881233 peak = 890564608
[M::mem_process_seqs] Processed 713180 reads in 372.476 CPU sec, 11.841 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 281840, 40, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 409, 1422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3806)
[M::mem_pestat] mean and std.dev: (719.15, 611.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4998)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 215, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 644)
[M::mem_pestat] mean and std.dev: (238.95, 118.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 810)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 920, 1748)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4812)
[M::mem_pestat] mean and std.dev: (956.81, 804.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6344)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 334, 1189)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3109)
[M::mem_pestat] mean and std.dev: (660.95, 618.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4069)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 35, #reads = 1072640 mem = 536881926 peak = 890564608
[M::process] read 706842 sequences (100000000 bp) in 3.035 CPU sec, 3.137 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 281958, 57, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (262, 495, 1030)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2566)
[M::mem_pestat] mean and std.dev: (573.61, 426.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3334)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 217, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 654)
[M::mem_pestat] mean and std.dev: (241.50, 120.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 823)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (439, 636, 1443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3451)
[M::mem_pestat] mean and std.dev: (849.49, 706.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4455)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (325, 705, 1835)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4855)
[M::mem_pestat] mean and std.dev: (920.22, 940.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6365)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706236 sequences (100000204 bp) in 1.935 CPU sec, 1.935 real sec...
[M::mem_process_seqs] Processed 708762 reads in 220.983 CPU sec, 7.015 real sec
[M::mem_process_seqs] Processed 708212 reads in 138.456 CPU sec, 4.381 real sec
sorting block 36, #reads = 1072348 mem = 536877659 peak = 890564608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 281650, 49, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 416, 981)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2575)
[M::mem_pestat] mean and std.dev: (703.51, 666.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3372)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 219, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 662)
[M::mem_pestat] mean and std.dev: (243.89, 121.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 833)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (336, 669, 1535)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3933)
[M::mem_pestat] mean and std.dev: (830.16, 709.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5132)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 607, 1518)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4114)
[M::mem_pestat] mean and std.dev: (1035.26, 1100.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5438)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705512 sequences (100000133 bp) in 2.704 CPU sec, 2.806 real sec...
[M::process] read 706516 sequences (100000087 bp) in 1.989 CPU sec, 1.994 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (87, 281534, 29, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 571, 1255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3389)
[M::mem_pestat] mean and std.dev: (830.64, 842.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4456)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 220, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 663)
[M::mem_pestat] mean and std.dev: (245.15, 122.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 242, 965)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2503)
[M::mem_pestat] mean and std.dev: (508.88, 544.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3272)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (274, 602, 722)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1618)
[M::mem_pestat] mean and std.dev: (529.76, 280.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2066)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706842 reads in 186.074 CPU sec, 5.887 real sec
sorting block 37, #reads = 1072215 mem = 536878768 peak = 890564608
[M::mem_process_seqs] Processed 706236 reads in 134.441 CPU sec, 4.267 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (86, 281471, 35, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 405, 974)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2458)
[M::mem_pestat] mean and std.dev: (457.97, 364.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3200)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 222, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 669)
[M::mem_pestat] mean and std.dev: (247.00, 123.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 842)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (291, 399, 1161)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2901)
[M::mem_pestat] mean and std.dev: (651.19, 624.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3771)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 339, 888)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2248)
[M::mem_pestat] mean and std.dev: (530.62, 488.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2928)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704698 sequences (100000129 bp) in 2.949 CPU sec, 3.018 real sec...
[M::process] read 704178 sequences (100000023 bp) in 2.140 CPU sec, 2.146 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 281540, 60, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 317, 554)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1334)
[M::mem_pestat] mean and std.dev: (364.56, 283.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1724)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 218, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 656)
[M::mem_pestat] mean and std.dev: (243.23, 120.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 825)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (322, 630, 1181)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2899)
[M::mem_pestat] mean and std.dev: (805.11, 694.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3758)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 365, 741)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1769)
[M::mem_pestat] mean and std.dev: (432.34, 333.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2283)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705512 reads in 192.497 CPU sec, 6.083 real sec
sorting block 38, #reads = 1071174 mem = 536890347 peak = 890564608
[M::mem_process_seqs] Processed 706516 reads in 220.483 CPU sec, 6.998 real sec
sorting block 39, #reads = 1069875 mem = 536878985 peak = 942247936
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 281103, 49, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 339, 831)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2053)
[M::mem_pestat] mean and std.dev: (441.16, 360.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2664)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (248.12, 122.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 844)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 639, 2128)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5922)
[M::mem_pestat] mean and std.dev: (780.90, 866.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7819)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 333, 1086)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2866)
[M::mem_pestat] mean and std.dev: (539.81, 537.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3756)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703904 sequences (100000260 bp) in 2.989 CPU sec, 3.063 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (86, 279888, 56, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 871, 1863)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5077)
[M::mem_pestat] mean and std.dev: (1235.38, 1311.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6684)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 225, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (248.23, 121.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 844)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (591, 1165, 1978)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4752)
[M::mem_pestat] mean and std.dev: (1140.21, 852.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6139)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 487, 909)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2215)
[M::mem_pestat] mean and std.dev: (546.92, 384.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2868)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704148 sequences (100000136 bp) in 2.190 CPU sec, 2.188 real sec...
[M::mem_process_seqs] Processed 704698 reads in 187.266 CPU sec, 5.920 real sec
[M::mem_process_seqs] Processed 704178 reads in 217.866 CPU sec, 6.905 real sec
sorting block 40, #reads = 1068510 mem = 536879122 peak = 942247936
[M::process] read 704446 sequences (100000023 bp) in 2.914 CPU sec, 2.965 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (79, 280462, 61, 81)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 379, 1154)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3014)
[M::mem_pestat] mean and std.dev: (637.12, 587.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3944)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 225, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 660)
[M::mem_pestat] mean and std.dev: (247.17, 120.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 829)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 531, 1354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3602)
[M::mem_pestat] mean and std.dev: (744.98, 849.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4726)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 360, 824)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2010)
[M::mem_pestat] mean and std.dev: (470.41, 428.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2603)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704526 sequences (100000073 bp) in 2.190 CPU sec, 2.199 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 280254, 38, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 393, 1823)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5051)
[M::mem_pestat] mean and std.dev: (885.03, 1033.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6665)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 223, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 659)
[M::mem_pestat] mean and std.dev: (246.08, 119.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 828)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (304, 1218, 2326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6370)
[M::mem_pestat] mean and std.dev: (1546.68, 1706.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8392)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 406, 982)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2514)
[M::mem_pestat] mean and std.dev: (527.92, 461.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3280)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703904 reads in 194.743 CPU sec, 6.152 real sec
[M::mem_process_seqs] Processed 704148 reads in 223.491 CPU sec, 7.088 real sec
sorting block 41, #reads = 1066997 mem = 536881588 peak = 942247936
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 280481, 51, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 342, 816)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2068)
[M::mem_pestat] mean and std.dev: (454.09, 398.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2694)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 223, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 662)
[M::mem_pestat] mean and std.dev: (246.03, 120.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 832)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (311, 765, 1902)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5084)
[M::mem_pestat] mean and std.dev: (1080.81, 1036.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6675)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 317, 670)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1562)
[M::mem_pestat] mean and std.dev: (404.93, 225.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2008)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704252 sequences (100000214 bp) in 2.900 CPU sec, 3.025 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (85, 280725, 54, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (278, 498, 1156)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2912)
[M::mem_pestat] mean and std.dev: (642.27, 495.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3790)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 223, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 659)
[M::mem_pestat] mean and std.dev: (245.53, 119.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 828)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (327, 1155, 1673)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4365)
[M::mem_pestat] mean and std.dev: (1093.52, 779.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5711)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 380, 1131)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3001)
[M::mem_pestat] mean and std.dev: (590.77, 583.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3936)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704556 sequences (100000263 bp) in 2.150 CPU sec, 2.147 real sec...
[M::mem_process_seqs] Processed 704446 reads in 192.264 CPU sec, 6.074 real sec
sorting block 42, #reads = 1067116 mem = 536878756 peak = 942247936
[M::mem_process_seqs] Processed 704526 reads in 137.162 CPU sec, 4.356 real sec
sorting block 43, #reads = 1068279 mem = 536887707 peak = 942247936
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 280051, 55, 86)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 486, 1323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3569)
[M::mem_pestat] mean and std.dev: (526.19, 512.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4692)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 665)
[M::mem_pestat] mean and std.dev: (247.39, 121.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 836)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (273, 654, 2155)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5919)
[M::mem_pestat] mean and std.dev: (1084.74, 1163.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7801)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 457, 1419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3803)
[M::mem_pestat] mean and std.dev: (717.89, 720.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4995)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706424 sequences (100000259 bp) in 2.740 CPU sec, 2.805 real sec...
[M::process] read 716440 sequences (100000206 bp) in 2.250 CPU sec, 2.245 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 280546, 40, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (255, 362, 856)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2058)
[M::mem_pestat] mean and std.dev: (516.26, 465.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2659)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 225, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (248.61, 123.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 848)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (403, 1047, 1961)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5077)
[M::mem_pestat] mean and std.dev: (1115.00, 1071.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6635)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 323, 711)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1709)
[M::mem_pestat] mean and std.dev: (369.00, 267.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2208)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704252 reads in 195.480 CPU sec, 6.176 real sec
[M::mem_process_seqs] Processed 704556 reads in 140.348 CPU sec, 4.454 real sec
sorting block 44, #reads = 1066104 mem = 536879509 peak = 942247936
[M::process] read 713632 sequences (100000199 bp) in 2.679 CPU sec, 2.720 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 281097, 43, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 287, 625)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1543)
[M::mem_pestat] mean and std.dev: (401.04, 349.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2002)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 220, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 660)
[M::mem_pestat] mean and std.dev: (244.56, 121.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 830)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (342, 662, 1605)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4131)
[M::mem_pestat] mean and std.dev: (953.85, 878.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5394)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (286, 470, 1083)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2677)
[M::mem_pestat] mean and std.dev: (601.98, 481.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3474)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 711784 sequences (100000016 bp) in 2.150 CPU sec, 2.151 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 283578, 38, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 373, 682)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1662)
[M::mem_pestat] mean and std.dev: (445.75, 349.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2152)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (141, 204, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 603)
[M::mem_pestat] mean and std.dev: (227.35, 111.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 757)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (407, 848, 2271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5999)
[M::mem_pestat] mean and std.dev: (1035.29, 906.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7863)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 394, 1050)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2772)
[M::mem_pestat] mean and std.dev: (644.31, 586.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3633)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 283912, 41, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 310, 809)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2071)
[M::mem_pestat] mean and std.dev: (473.43, 436.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2702)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 198, 283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 573)
[M::mem_pestat] mean and std.dev: (219.55, 106.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 718)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (262, 545, 1544)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4108)
[M::mem_pestat] mean and std.dev: (819.87, 792.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5390)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 355, 1257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3415)
[M::mem_pestat] mean and std.dev: (546.32, 538.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4494)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706424 reads in 296.614 CPU sec, 9.447 real sec
sorting block 45, #reads = 1065635 mem = 536877790 peak = 942247936
[M::mem_process_seqs] Processed 713632 reads in 236.217 CPU sec, 7.558 real sec
[M::mem_process_seqs] Processed 716440 reads in 269.505 CPU sec, 8.624 real sec
[M::process] read 709824 sequences (100000151 bp) in 2.892 CPU sec, 2.999 real sec...
sorting block 46, #reads = 1070321 mem = 536879153 peak = 942247936
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (83, 283275, 38, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 498, 858)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2088)
[M::mem_pestat] mean and std.dev: (510.18, 390.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2703)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 208, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 617)
[M::mem_pestat] mean and std.dev: (231.55, 114.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 775)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (369, 784, 1799)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4659)
[M::mem_pestat] mean and std.dev: (1280.58, 1167.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6089)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 341, 939)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2363)
[M::mem_pestat] mean and std.dev: (565.60, 565.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3075)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 709286 sequences (100000201 bp) in 2.010 CPU sec, 2.066 real sec...
[M::process] read 708756 sequences (100000218 bp) in 1.590 CPU sec, 1.598 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 283028, 30, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 434, 1532)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4230)
[M::mem_pestat] mean and std.dev: (875.34, 991.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5579)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 211, 308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 634)
[M::mem_pestat] mean and std.dev: (236.13, 117.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 797)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (322, 809, 1362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3442)
[M::mem_pestat] mean and std.dev: (620.44, 412.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4482)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 490, 1749)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4755)
[M::mem_pestat] mean and std.dev: (881.77, 1026.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6258)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 711784 reads in 197.442 CPU sec, 6.272 real sec
[M::mem_process_seqs] Processed 709824 reads in 137.805 CPU sec, 4.373 real sec
sorting block 47, #reads = 1069860 mem = 536879996 peak = 942247936
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 282701, 39, 86)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 361, 1119)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2917)
[M::mem_pestat] mean and std.dev: (597.71, 523.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3816)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 212, 310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 640)
[M::mem_pestat] mean and std.dev: (237.84, 118.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 805)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (266, 524, 1544)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4100)
[M::mem_pestat] mean and std.dev: (827.33, 889.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5378)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 356, 1363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3661)
[M::mem_pestat] mean and std.dev: (681.64, 775.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4810)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708862 sequences (100000131 bp) in 2.601 CPU sec, 2.694 real sec...
[M::process] read 708712 sequences (100000301 bp) in 1.729 CPU sec, 1.737 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 282648, 49, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 385, 1341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3585)
[M::mem_pestat] mean and std.dev: (791.44, 752.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4707)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 213, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 644)
[M::mem_pestat] mean and std.dev: (239.19, 119.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 810)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (481, 958, 1785)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4393)
[M::mem_pestat] mean and std.dev: (995.16, 828.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5697)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 448, 876)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2120)
[M::mem_pestat] mean and std.dev: (495.90, 352.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2742)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 709286 reads in 192.021 CPU sec, 6.089 real sec
sorting block 48, #reads = 1070632 mem = 536880578 peak = 942247936
[M::mem_process_seqs] Processed 708756 reads in 135.853 CPU sec, 4.324 real sec
sorting block 49, #reads = 1071039 mem = 536889739 peak = 960425984
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 282416, 41, 87)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 450, 629)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1505)
[M::mem_pestat] mean and std.dev: (438.30, 330.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1943)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 214, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 647)
[M::mem_pestat] mean and std.dev: (239.62, 119.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 814)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 479, 1535)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4335)
[M::mem_pestat] mean and std.dev: (789.37, 890.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5735)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 410, 942)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2364)
[M::mem_pestat] mean and std.dev: (531.91, 493.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3075)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708330 sequences (100000222 bp) in 2.730 CPU sec, 2.788 real sec...
[M::process] read 708238 sequences (100000178 bp) in 2.250 CPU sec, 2.243 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 282727, 54, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 334, 955)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2565)
[M::mem_pestat] mean and std.dev: (559.20, 553.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3370)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 214, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 645)
[M::mem_pestat] mean and std.dev: (239.74, 119.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 811)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (326, 1081, 1250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3098)
[M::mem_pestat] mean and std.dev: (828.82, 573.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4022)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 717, 1754)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4800)
[M::mem_pestat] mean and std.dev: (1007.75, 955.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6323)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 708712 reads in 186.877 CPU sec, 5.899 real sec
[M::mem_process_seqs] Processed 708862 reads in 213.305 CPU sec, 6.757 real sec
sorting block 50, #reads = 1069380 mem = 536880677 peak = 960425984
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 282111, 60, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (254, 506, 1005)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2507)
[M::mem_pestat] mean and std.dev: (612.68, 502.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3258)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 214, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 645)
[M::mem_pestat] mean and std.dev: (239.68, 119.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 811)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (246, 499, 1752)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4764)
[M::mem_pestat] mean and std.dev: (870.91, 947.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6270)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 271, 712)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1724)
[M::mem_pestat] mean and std.dev: (422.48, 339.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2230)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707448 sequences (100000254 bp) in 2.940 CPU sec, 3.012 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 281897, 41, 101)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 495, 688)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1682)
[M::mem_pestat] mean and std.dev: (511.58, 406.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2179)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 215, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 645)
[M::mem_pestat] mean and std.dev: (239.58, 119.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 811)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (289, 552, 1816)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4870)
[M::mem_pestat] mean and std.dev: (1227.73, 1365.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6691)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (315, 518, 1014)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2412)
[M::mem_pestat] mean and std.dev: (653.32, 471.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3111)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706114 sequences (100000282 bp) in 2.230 CPU sec, 2.234 real sec...
[M::mem_process_seqs] Processed 708330 reads in 186.259 CPU sec, 5.876 real sec
sorting block 51, #reads = 1070221 mem = 536880671 peak = 960425984
[M::mem_process_seqs] Processed 708238 reads in 213.772 CPU sec, 6.772 real sec
[M::process] read 705888 sequences (100000070 bp) in 2.552 CPU sec, 2.625 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 280597, 47, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 357, 1063)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2771)
[M::mem_pestat] mean and std.dev: (614.42, 599.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3625)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 218, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 650)
[M::mem_pestat] mean and std.dev: (242.29, 119.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 817)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (130, 386, 1578)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4474)
[M::mem_pestat] mean and std.dev: (794.35, 986.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5922)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 337, 938)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2320)
[M::mem_pestat] mean and std.dev: (549.52, 486.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3011)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705178 sequences (100000285 bp) in 1.700 CPU sec, 1.706 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (93, 281497, 45, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 304, 1043)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2777)
[M::mem_pestat] mean and std.dev: (615.82, 664.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3644)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 215, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 643)
[M::mem_pestat] mean and std.dev: (240.40, 119.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 808)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (273, 650, 2941)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8277)
[M::mem_pestat] mean and std.dev: (1532.95, 1676.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10945)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 291, 997)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2525)
[M::mem_pestat] mean and std.dev: (591.69, 516.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3289)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706114 reads in 197.439 CPU sec, 6.267 real sec
sorting block 52, #reads = 1067105 mem = 536884993 peak = 960425984
[M::mem_process_seqs] Processed 707448 reads in 226.573 CPU sec, 7.212 real sec
sorting block 53, #reads = 1066140 mem = 536886566 peak = 962011136
[M::process] read 705498 sequences (100000108 bp) in 2.649 CPU sec, 2.703 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (91, 280632, 49, 98)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (277, 517, 1069)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2653)
[M::mem_pestat] mean and std.dev: (639.28, 502.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3445)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 221, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (245.87, 121.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 831)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 586, 3287)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9529)
[M::mem_pestat] mean and std.dev: (1871.86, 2298.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12650)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 339, 1379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3697)
[M::mem_pestat] mean and std.dev: (764.05, 871.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4856)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 710182 sequences (100000052 bp) in 1.730 CPU sec, 1.728 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (92, 280368, 57, 84)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 434, 974)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2496)
[M::mem_pestat] mean and std.dev: (563.27, 540.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3257)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 220, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 654)
[M::mem_pestat] mean and std.dev: (243.89, 120.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 822)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (94, 381, 1074)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3034)
[M::mem_pestat] mean and std.dev: (553.87, 600.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4014)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 379, 929)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2397)
[M::mem_pestat] mean and std.dev: (523.00, 470.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3131)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705178 reads in 190.797 CPU sec, 6.039 real sec
[M::mem_process_seqs] Processed 705888 reads in 219.051 CPU sec, 6.956 real sec
sorting block 54, #reads = 1062941 mem = 536878287 peak = 962011136
[M::process] read 721772 sequences (100000039 bp) in 2.736 CPU sec, 2.807 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (83, 282105, 49, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 333, 1008)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2662)
[M::mem_pestat] mean and std.dev: (529.13, 552.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3489)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 210, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 625)
[M::mem_pestat] mean and std.dev: (234.42, 115.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 785)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (367, 611, 989)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2233)
[M::mem_pestat] mean and std.dev: (642.70, 505.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2855)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 386, 1050)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2670)
[M::mem_pestat] mean and std.dev: (670.60, 583.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3480)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717880 sequences (100000035 bp) in 1.960 CPU sec, 1.959 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 280564, 60, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 307, 851)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2195)
[M::mem_pestat] mean and std.dev: (510.53, 506.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2867)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 221, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 663)
[M::mem_pestat] mean and std.dev: (245.24, 121.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 403, 1023)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2729)
[M::mem_pestat] mean and std.dev: (596.69, 632.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3582)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 357, 826)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2110)
[M::mem_pestat] mean and std.dev: (523.11, 483.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2752)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 710182 reads in 215.404 CPU sec, 6.832 real sec
sorting block 55, #reads = 1062398 mem = 536882223 peak = 962011136
[M::mem_process_seqs] Processed 705498 reads in 247.411 CPU sec, 7.864 real sec
[M::process] read 715632 sequences (100000246 bp) in 2.846 CPU sec, 2.920 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 285761, 41, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 280, 710)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1818)
[M::mem_pestat] mean and std.dev: (394.47, 333.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2372)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 190, 270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 542)
[M::mem_pestat] mean and std.dev: (210.28, 100.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 678)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (283, 873, 3495)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9919)
[M::mem_pestat] mean and std.dev: (1771.83, 1988.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13131)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 372, 1141)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3029)
[M::mem_pestat] mean and std.dev: (605.91, 616.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3973)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 713096 sequences (100000225 bp) in 2.080 CPU sec, 2.080 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 285179, 47, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 341, 959)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2491)
[M::mem_pestat] mean and std.dev: (462.62, 432.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3257)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 196, 281)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 569)
[M::mem_pestat] mean and std.dev: (218.23, 105.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 713)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (456, 860, 1475)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3513)
[M::mem_pestat] mean and std.dev: (936.33, 753.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4532)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 516, 1866)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5146)
[M::mem_pestat] mean and std.dev: (911.33, 812.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6786)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 721772 reads in 242.410 CPU sec, 7.698 real sec
sorting block 56, #reads = 1061382 mem = 536879502 peak = 962011136
[M::mem_process_seqs] Processed 717880 reads in 277.475 CPU sec, 8.828 real sec
sorting block 57, #reads = 1060563 mem = 536883650 peak = 989732864
[M::process] read 711312 sequences (100000199 bp) in 2.538 CPU sec, 2.610 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 284387, 43, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 282, 753)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1895)
[M::mem_pestat] mean and std.dev: (443.61, 397.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2466)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 200, 289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 589)
[M::mem_pestat] mean and std.dev: (223.60, 109.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 739)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 623, 1316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3452)
[M::mem_pestat] mean and std.dev: (741.55, 679.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4520)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 443, 1113)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2911)
[M::mem_pestat] mean and std.dev: (620.09, 587.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3810)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 710142 sequences (100000111 bp) in 1.720 CPU sec, 1.722 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 284521, 42, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 230, 545)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1323)
[M::mem_pestat] mean and std.dev: (344.19, 303.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1712)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 204, 296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 604)
[M::mem_pestat] mean and std.dev: (228.42, 112.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 758)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 1221, 2263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6311)
[M::mem_pestat] mean and std.dev: (1265.46, 1145.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8335)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 434, 1403)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3767)
[M::mem_pestat] mean and std.dev: (724.10, 678.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4949)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 715632 reads in 218.785 CPU sec, 6.955 real sec
[M::mem_process_seqs] Processed 713096 reads in 250.469 CPU sec, 7.973 real sec
sorting block 58, #reads = 1062443 mem = 536879711 peak = 989732864
[M::process] read 709362 sequences (100000258 bp) in 3.003 CPU sec, 3.054 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 283294, 57, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 359, 1086)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2846)
[M::mem_pestat] mean and std.dev: (592.58, 541.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3726)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 208, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 618)
[M::mem_pestat] mean and std.dev: (232.22, 114.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 776)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (363, 653, 1965)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5169)
[M::mem_pestat] mean and std.dev: (1110.35, 1121.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6771)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (259, 439, 1100)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2782)
[M::mem_pestat] mean and std.dev: (699.48, 653.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3623)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 709048 sequences (100000012 bp) in 2.270 CPU sec, 2.267 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 283610, 38, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 297, 941)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2451)
[M::mem_pestat] mean and std.dev: (455.60, 443.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3206)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 210, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 628)
[M::mem_pestat] mean and std.dev: (235.04, 116.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 789)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (306, 969, 2277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6219)
[M::mem_pestat] mean and std.dev: (1464.81, 1723.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8357)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 379, 769)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1885)
[M::mem_pestat] mean and std.dev: (502.01, 412.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2443)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 711312 reads in 210.687 CPU sec, 6.663 real sec
sorting block 59, #reads = 1064116 mem = 536880186 peak = 989732864
[M::process] read 708286 sequences (100000276 bp) in 2.088 CPU sec, 2.097 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 282991, 47, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 250, 677)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1701)
[M::mem_pestat] mean and std.dev: (387.33, 388.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2213)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 212, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 629)
[M::mem_pestat] mean and std.dev: (235.91, 116.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 790)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 578, 900)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2170)
[M::mem_pestat] mean and std.dev: (571.84, 409.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2805)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 324, 636)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1428)
[M::mem_pestat] mean and std.dev: (401.69, 275.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1824)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 709048 reads in 121.367 CPU sec, 3.891 real sec
[M::mem_process_seqs] Processed 710142 reads in 392.098 CPU sec, 12.491 real sec
sorting block 60, #reads = 1066371 mem = 536884386 peak = 989732864
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 282719, 43, 94)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 379, 987)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2567)
[M::mem_pestat] mean and std.dev: (514.73, 493.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3357)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 211, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 629)
[M::mem_pestat] mean and std.dev: (235.80, 116.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 790)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 579, 1496)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4110)
[M::mem_pestat] mean and std.dev: (654.74, 633.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5417)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 315, 943)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2427)
[M::mem_pestat] mean and std.dev: (502.46, 539.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3169)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707190 sequences (100000205 bp) in 2.425 CPU sec, 2.566 real sec...
[M::process] read 706156 sequences (100000118 bp) in 1.689 CPU sec, 1.698 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 281846, 45, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 403, 917)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2325)
[M::mem_pestat] mean and std.dev: (541.98, 462.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3029)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 214, 311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 639)
[M::mem_pestat] mean and std.dev: (238.98, 118.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 803)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (479, 1273, 3112)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8378)
[M::mem_pestat] mean and std.dev: (1665.64, 1543.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11011)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (274, 394, 1149)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2899)
[M::mem_pestat] mean and std.dev: (648.88, 591.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3774)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 709362 reads in 330.305 CPU sec, 10.524 real sec
sorting block 61, #reads = 1066369 mem = 536889660 peak = 989732864
[M::mem_process_seqs] Processed 708286 reads in 148.513 CPU sec, 4.731 real sec
[M::process] read 705446 sequences (100000201 bp) in 2.670 CPU sec, 2.763 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (79, 281095, 32, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 389, 1547)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4161)
[M::mem_pestat] mean and std.dev: (722.04, 840.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5468)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 216, 314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 646)
[M::mem_pestat] mean and std.dev: (241.07, 120.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 812)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (588, 861, 2998)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7818)
[M::mem_pestat] mean and std.dev: (1870.48, 2273.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10964)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 358, 1140)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2930)
[M::mem_pestat] mean and std.dev: (562.55, 544.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3825)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705358 sequences (100000275 bp) in 2.240 CPU sec, 2.247 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (98, 280509, 47, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 441, 749)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1865)
[M::mem_pestat] mean and std.dev: (503.89, 396.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2423)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 218, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653)
[M::mem_pestat] mean and std.dev: (242.95, 120.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 821)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (468, 957, 1487)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3525)
[M::mem_pestat] mean and std.dev: (954.62, 771.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4544)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 391, 1076)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2756)
[M::mem_pestat] mean and std.dev: (643.76, 639.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3596)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707190 reads in 218.986 CPU sec, 6.944 real sec
sorting block 62, #reads = 1066012 mem = 536877779 peak = 989732864
[M::mem_process_seqs] Processed 706156 reads in 251.730 CPU sec, 8.014 real sec
sorting block 63, #reads = 1065437 mem = 536877181 peak = 1036845056
[M::process] read 708692 sequences (100000025 bp) in 2.816 CPU sec, 2.885 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (85, 280770, 44, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 386, 1553)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4245)
[M::mem_pestat] mean and std.dev: (723.75, 890.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5591)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 219, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 657)
[M::mem_pestat] mean and std.dev: (244.35, 121.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 826)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (380, 1438, 2353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6299)
[M::mem_pestat] mean and std.dev: (1510.76, 1426.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8272)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 364, 1074)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2764)
[M::mem_pestat] mean and std.dev: (628.26, 624.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3609)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 715014 sequences (100000204 bp) in 2.340 CPU sec, 2.338 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (84, 280763, 50, 91)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (267, 435, 1465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3861)
[M::mem_pestat] mean and std.dev: (789.96, 849.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5059)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 220, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 660)
[M::mem_pestat] mean and std.dev: (245.16, 122.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 830)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (296, 613, 1118)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2762)
[M::mem_pestat] mean and std.dev: (633.64, 506.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3584)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 433, 984)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2458)
[M::mem_pestat] mean and std.dev: (620.11, 593.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3195)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 280757, 64, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (255, 433, 1255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3255)
[M::mem_pestat] mean and std.dev: (690.04, 637.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4255)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 213, 309)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 635)
[M::mem_pestat] mean and std.dev: (237.13, 117.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 798)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (112, 514, 1145)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3211)
[M::mem_pestat] mean and std.dev: (650.21, 682.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4244)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 398, 907)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2249)
[M::mem_pestat] mean and std.dev: (517.88, 416.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2920)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705446 reads in 316.848 CPU sec, 10.082 real sec
[M::mem_process_seqs] Processed 705358 reads in 257.124 CPU sec, 8.219 real sec
sorting block 64, #reads = 1066133 mem = 536877671 peak = 1036845056
[M::mem_process_seqs] Processed 708692 reads in 301.130 CPU sec, 9.620 real sec
[M::process] read 711484 sequences (100000234 bp) in 3.206 CPU sec, 3.311 real sec...
sorting block 65, #reads = 1060829 mem = 536877422 peak = 1036845056
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 283691, 42, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 251, 685)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1691)
[M::mem_pestat] mean and std.dev: (349.31, 293.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2194)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (140, 201, 289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 587)
[M::mem_pestat] mean and std.dev: (223.37, 108.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 736)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (298, 792, 1699)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4501)
[M::mem_pestat] mean and std.dev: (872.00, 919.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5902)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 410, 846)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2082)
[M::mem_pestat] mean and std.dev: (565.03, 447.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2700)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 710344 sequences (100000029 bp) in 2.481 CPU sec, 2.520 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 283397, 57, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (254, 470, 932)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2288)
[M::mem_pestat] mean and std.dev: (579.79, 518.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2966)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 208, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 615)
[M::mem_pestat] mean and std.dev: (231.65, 113.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 772)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 636, 1414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3888)
[M::mem_pestat] mean and std.dev: (820.81, 836.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5125)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 447, 894)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2168)
[M::mem_pestat] mean and std.dev: (535.90, 429.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2805)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 709138 sequences (100000008 bp) in 2.180 CPU sec, 2.185 real sec...
[M::mem_process_seqs] Processed 715014 reads in 222.728 CPU sec, 7.029 real sec
[M::mem_process_seqs] Processed 711484 reads in 155.010 CPU sec, 4.901 real sec
sorting block 66, #reads = 1064195 mem = 536879610 peak = 1036845056
[M::process] read 708136 sequences (100000011 bp) in 2.999 CPU sec, 3.096 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 282595, 39, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 525, 1025)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2611)
[M::mem_pestat] mean and std.dev: (595.15, 484.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3404)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 213, 309)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 635)
[M::mem_pestat] mean and std.dev: (237.33, 116.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 798)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 534, 1024)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2598)
[M::mem_pestat] mean and std.dev: (619.97, 586.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3385)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 368, 973)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2493)
[M::mem_pestat] mean and std.dev: (604.61, 607.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3253)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707472 sequences (100000238 bp) in 2.210 CPU sec, 2.208 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 282884, 49, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (281, 448, 1315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3383)
[M::mem_pestat] mean and std.dev: (778.99, 742.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4417)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 211, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 631)
[M::mem_pestat] mean and std.dev: (235.41, 116.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 793)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 622, 1827)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5041)
[M::mem_pestat] mean and std.dev: (1097.23, 1094.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6648)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 363, 998)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2480)
[M::mem_pestat] mean and std.dev: (604.51, 494.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3221)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 709138 reads in 209.250 CPU sec, 6.618 real sec
sorting block 67, #reads = 1070187 mem = 536877565 peak = 1036845056
[M::mem_process_seqs] Processed 710344 reads in 241.138 CPU sec, 7.648 real sec
[M::process] read 707712 sequences (100000274 bp) in 2.742 CPU sec, 2.837 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (90, 282459, 38, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 659, 1585)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4227)
[M::mem_pestat] mean and std.dev: (793.10, 747.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5548)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 215, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 642)
[M::mem_pestat] mean and std.dev: (239.16, 118.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 807)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (440, 1066, 1477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3551)
[M::mem_pestat] mean and std.dev: (970.50, 737.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4588)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (278, 456, 853)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2003)
[M::mem_pestat] mean and std.dev: (579.68, 383.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2578)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707808 sequences (100000032 bp) in 2.350 CPU sec, 2.353 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 282438, 54, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 409, 818)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1982)
[M::mem_pestat] mean and std.dev: (498.29, 413.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2564)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 217, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 652)
[M::mem_pestat] mean and std.dev: (241.85, 119.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 820)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (428, 1195, 2802)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7550)
[M::mem_pestat] mean and std.dev: (1683.89, 1653.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9924)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 342, 1191)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3163)
[M::mem_pestat] mean and std.dev: (724.38, 728.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4149)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 708136 reads in 201.109 CPU sec, 6.355 real sec
sorting block 68, #reads = 1071209 mem = 536879874 peak = 1036845056
[M::mem_process_seqs] Processed 707472 reads in 230.693 CPU sec, 7.315 real sec
sorting block 69, #reads = 1069899 mem = 536879493 peak = 1049694208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (89, 282621, 38, 98)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (268, 598, 1281)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3307)
[M::mem_pestat] mean and std.dev: (733.60, 623.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4320)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 216, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 640)
[M::mem_pestat] mean and std.dev: (239.58, 117.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 804)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (408, 987, 1743)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4413)
[M::mem_pestat] mean and std.dev: (1130.97, 915.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5748)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 292, 1138)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3042)
[M::mem_pestat] mean and std.dev: (613.27, 683.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3994)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707114 sequences (100000014 bp) in 3.037 CPU sec, 3.099 real sec...
[M::process] read 706092 sequences (100000099 bp) in 2.270 CPU sec, 2.270 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 282211, 30, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 332, 1074)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2832)
[M::mem_pestat] mean and std.dev: (560.34, 552.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3711)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 215, 311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 639)
[M::mem_pestat] mean and std.dev: (239.01, 117.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 803)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (425, 1011, 1871)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4763)
[M::mem_pestat] mean and std.dev: (1178.97, 826.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6209)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 383, 930)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2364)
[M::mem_pestat] mean and std.dev: (476.98, 418.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3081)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707712 reads in 201.213 CPU sec, 6.353 real sec
[M::mem_process_seqs] Processed 707808 reads in 233.567 CPU sec, 7.403 real sec
sorting block 70, #reads = 1071619 mem = 536879122 peak = 1049694208
[M::process] read 706160 sequences (100000240 bp) in 2.769 CPU sec, 2.855 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 281798, 30, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 420, 1125)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3073)
[M::mem_pestat] mean and std.dev: (652.98, 684.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4047)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 217, 314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 646)
[M::mem_pestat] mean and std.dev: (241.05, 119.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 812)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (588, 769, 4702)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12930)
[M::mem_pestat] mean and std.dev: (2430.30, 3075.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17044)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (286, 472, 1279)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3265)
[M::mem_pestat] mean and std.dev: (879.88, 881.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4405)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706036 sequences (100000078 bp) in 2.300 CPU sec, 2.297 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 280907, 58, 85)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (314, 592, 1367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3473)
[M::mem_pestat] mean and std.dev: (764.77, 710.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4526)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 218, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 656)
[M::mem_pestat] mean and std.dev: (243.67, 121.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 825)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 521, 1465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4129)
[M::mem_pestat] mean and std.dev: (871.39, 810.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5461)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (266, 546, 1114)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2810)
[M::mem_pestat] mean and std.dev: (693.84, 580.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3658)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 280345, 48, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 294, 729)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1841)
[M::mem_pestat] mean and std.dev: (435.84, 356.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2397)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 218, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653)
[M::mem_pestat] mean and std.dev: (242.80, 120.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 821)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (422, 615, 1181)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2699)
[M::mem_pestat] mean and std.dev: (750.39, 520.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3458)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 376, 696)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1722)
[M::mem_pestat] mean and std.dev: (449.20, 353.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2235)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707114 reads in 300.226 CPU sec, 9.552 real sec
sorting block 71, #reads = 1068163 mem = 536882577 peak = 1049694208
[M::mem_process_seqs] Processed 706092 reads in 239.098 CPU sec, 7.652 real sec
[M::mem_process_seqs] Processed 706160 reads in 273.087 CPU sec, 8.742 real sec
sorting block 72, #reads = 1066589 mem = 536881413 peak = 1049694208
[M::process] read 704856 sequences (100000217 bp) in 3.366 CPU sec, 3.496 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 280435, 51, 85)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 313, 897)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2303)
[M::mem_pestat] mean and std.dev: (459.44, 388.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3006)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 218, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 647)
[M::mem_pestat] mean and std.dev: (242.18, 119.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 813)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (246, 818, 1720)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4668)
[M::mem_pestat] mean and std.dev: (856.89, 839.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6142)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 468, 1261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3327)
[M::mem_pestat] mean and std.dev: (695.21, 723.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4360)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705664 sequences (100000290 bp) in 2.519 CPU sec, 2.561 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 280328, 54, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 535, 1269)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3363)
[M::mem_pestat] mean and std.dev: (696.76, 645.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4410)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 220, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 658)
[M::mem_pestat] mean and std.dev: (245.28, 121.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 827)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 567, 972)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2606)
[M::mem_pestat] mean and std.dev: (543.35, 512.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3423)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (292, 464, 1907)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5137)
[M::mem_pestat] mean and std.dev: (953.62, 1106.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6752)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706036 reads in 221.745 CPU sec, 7.004 real sec
[M::process] read 705174 sequences (100000118 bp) in 2.309 CPU sec, 2.305 real sec...
sorting block 73, #reads = 1066125 mem = 536882062 peak = 1049694208
[M::mem_process_seqs] Processed 704856 reads in 158.052 CPU sec, 4.977 real sec
[M::process] read 718770 sequences (100000042 bp) in 2.459 CPU sec, 2.560 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (88, 280326, 42, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 344, 672)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1668)
[M::mem_pestat] mean and std.dev: (416.75, 341.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2166)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 219, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 654)
[M::mem_pestat] mean and std.dev: (243.78, 120.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 822)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (291, 672, 1466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3816)
[M::mem_pestat] mean and std.dev: (965.37, 970.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4991)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 421, 1148)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2962)
[M::mem_pestat] mean and std.dev: (712.52, 763.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3869)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717666 sequences (100000076 bp) in 1.800 CPU sec, 1.802 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (99, 280169, 57, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 397, 906)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2272)
[M::mem_pestat] mean and std.dev: (514.78, 439.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2955)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 220, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 657)
[M::mem_pestat] mean and std.dev: (244.79, 121.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 826)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (358, 525, 1474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3706)
[M::mem_pestat] mean and std.dev: (655.80, 510.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4822)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 451, 1257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3313)
[M::mem_pestat] mean and std.dev: (714.49, 675.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4341)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 284129, 52, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 432, 916)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2350)
[M::mem_pestat] mean and std.dev: (526.62, 501.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3067)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 194, 277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 559)
[M::mem_pestat] mean and std.dev: (215.17, 103.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 700)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (333, 845, 1376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3462)
[M::mem_pestat] mean and std.dev: (715.24, 618.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4505)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 585, 1419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3813)
[M::mem_pestat] mean and std.dev: (758.03, 787.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5010)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705664 reads in 348.149 CPU sec, 11.122 real sec
sorting block 74, #reads = 1064182 mem = 536883330 peak = 1049694208
[M::mem_process_seqs] Processed 705174 reads in 285.198 CPU sec, 9.165 real sec
sorting block 75, #reads = 1061940 mem = 536880546 peak = 1094008832
[M::mem_process_seqs] Processed 718770 reads in 331.875 CPU sec, 10.650 real sec
[M::process] read 714238 sequences (100000072 bp) in 2.715 CPU sec, 2.814 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 284970, 33, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 445, 974)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2492)
[M::mem_pestat] mean and std.dev: (635.36, 551.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3251)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 197, 284)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 578)
[M::mem_pestat] mean and std.dev: (219.67, 107.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 725)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 676, 3203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9177)
[M::mem_pestat] mean and std.dev: (1483.42, 1670.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12164)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 359, 1850)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5086)
[M::mem_pestat] mean and std.dev: (1045.23, 1200.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6704)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 711964 sequences (100000012 bp) in 2.647 CPU sec, 2.686 real sec...
[M::process] read 710598 sequences (100000296 bp) in 2.280 CPU sec, 2.282 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 283938, 44, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 398, 1590)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4376)
[M::mem_pestat] mean and std.dev: (797.06, 915.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5769)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (140, 203, 294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 602)
[M::mem_pestat] mean and std.dev: (226.74, 111.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 756)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (381, 787, 1510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3768)
[M::mem_pestat] mean and std.dev: (932.61, 808.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4897)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 397, 1492)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3988)
[M::mem_pestat] mean and std.dev: (758.69, 793.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5236)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 717666 reads in 254.997 CPU sec, 8.060 real sec
sorting block 76, #reads = 1054278 mem = 536880504 peak = 1094008832
[M::mem_process_seqs] Processed 714238 reads in 181.395 CPU sec, 5.766 real sec
sorting block 77, #reads = 1060329 mem = 536884535 peak = 1097129984
[M::process] read 708504 sequences (100000226 bp) in 2.988 CPU sec, 3.068 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 282534, 26, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 440, 1415)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3815)
[M::mem_pestat] mean and std.dev: (742.35, 771.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5015)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 208, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 620)
[M::mem_pestat] mean and std.dev: (232.38, 115.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 779)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 895, 1243)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3337)
[M::mem_pestat] mean and std.dev: (853.69, 671.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4384)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (300, 488, 743)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1629)
[M::mem_pestat] mean and std.dev: (520.08, 343.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2072)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708342 sequences (100000030 bp) in 2.320 CPU sec, 2.325 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 282604, 42, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 368, 548)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1312)
[M::mem_pestat] mean and std.dev: (357.18, 272.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1694)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 210, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 633)
[M::mem_pestat] mean and std.dev: (235.36, 117.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 796)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (303, 893, 1253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3153)
[M::mem_pestat] mean and std.dev: (871.23, 775.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4103)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 449, 724)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1720)
[M::mem_pestat] mean and std.dev: (460.68, 320.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2218)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 711964 reads in 231.878 CPU sec, 7.342 real sec
[M::mem_process_seqs] Processed 710598 reads in 266.890 CPU sec, 8.481 real sec
sorting block 78, #reads = 1061590 mem = 536882134 peak = 1097129984
[M::process] read 707020 sequences (100000061 bp) in 2.670 CPU sec, 2.726 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (79, 281551, 55, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 364, 1270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3372)
[M::mem_pestat] mean and std.dev: (851.79, 906.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4479)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 214, 310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 636)
[M::mem_pestat] mean and std.dev: (238.47, 118.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 799)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (281, 738, 1437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3749)
[M::mem_pestat] mean and std.dev: (739.90, 620.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4905)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 418, 894)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2222)
[M::mem_pestat] mean and std.dev: (538.39, 455.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2886)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706258 sequences (100000024 bp) in 2.270 CPU sec, 2.274 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (87, 282484, 53, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 491, 1065)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2735)
[M::mem_pestat] mean and std.dev: (714.94, 694.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3570)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 214, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 645)
[M::mem_pestat] mean and std.dev: (239.67, 119.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 811)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 439, 1911)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5331)
[M::mem_pestat] mean and std.dev: (835.60, 1077.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7041)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 529, 1129)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2877)
[M::mem_pestat] mean and std.dev: (625.99, 553.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3751)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 708342 reads in 226.110 CPU sec, 7.159 real sec
sorting block 79, #reads = 1062482 mem = 536884913 peak = 1097129984
[M::mem_process_seqs] Processed 708504 reads in 261.318 CPU sec, 8.296 real sec
[M::process] read 705768 sequences (100000123 bp) in 3.053 CPU sec, 3.126 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 280605, 49, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 420, 1172)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3100)
[M::mem_pestat] mean and std.dev: (662.30, 678.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4064)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 219, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 651)
[M::mem_pestat] mean and std.dev: (243.09, 120.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 818)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 337, 932)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2496)
[M::mem_pestat] mean and std.dev: (364.76, 313.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3278)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 311, 604)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1430)
[M::mem_pestat] mean and std.dev: (341.54, 217.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1843)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705066 sequences (100000186 bp) in 2.300 CPU sec, 2.299 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 281618, 42, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 244, 957)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2501)
[M::mem_pestat] mean and std.dev: (441.67, 491.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3273)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 217, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 658)
[M::mem_pestat] mean and std.dev: (243.17, 121.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 828)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 456, 1398)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3918)
[M::mem_pestat] mean and std.dev: (723.32, 876.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5178)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 397, 1139)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2945)
[M::mem_pestat] mean and std.dev: (638.59, 678.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3848)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706258 reads in 223.889 CPU sec, 7.092 real sec
sorting block 80, #reads = 1063977 mem = 536885199 peak = 1097129984
[M::mem_process_seqs] Processed 707020 reads in 258.272 CPU sec, 8.204 real sec
sorting block 81, #reads = 1061849 mem = 536888185 peak = 1127165952
[M::process] read 704342 sequences (100000066 bp) in 2.160 CPU sec, 2.256 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 280417, 36, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 407, 1376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3698)
[M::mem_pestat] mean and std.dev: (722.22, 797.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4859)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 219, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 651)
[M::mem_pestat] mean and std.dev: (243.42, 120.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 818)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 747, 1669)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4723)
[M::mem_pestat] mean and std.dev: (676.43, 725.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6250)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 293, 1170)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3112)
[M::mem_pestat] mean and std.dev: (629.91, 604.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4083)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704394 sequences (100000105 bp) in 1.750 CPU sec, 1.754 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (92, 279899, 48, 87)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 392, 976)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2610)
[M::mem_pestat] mean and std.dev: (592.88, 593.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3427)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 220, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 652)
[M::mem_pestat] mean and std.dev: (244.11, 120.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 819)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 515, 1854)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5068)
[M::mem_pestat] mean and std.dev: (979.85, 1029.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6675)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 309, 660)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1552)
[M::mem_pestat] mean and std.dev: (390.49, 279.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1998)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705768 reads in 192.773 CPU sec, 6.113 real sec
sorting block 82, #reads = 1062797 mem = 536878295 peak = 1127165952
[M::mem_process_seqs] Processed 705066 reads in 220.268 CPU sec, 7.004 real sec
[M::process] read 704548 sequences (100000014 bp) in 2.367 CPU sec, 2.435 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 280211, 32, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 321, 890)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2390)
[M::mem_pestat] mean and std.dev: (466.38, 445.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3140)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 222, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 656)
[M::mem_pestat] mean and std.dev: (245.61, 120.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 824)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 362, 1255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3441)
[M::mem_pestat] mean and std.dev: (574.13, 563.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4534)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 313, 606)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1480)
[M::mem_pestat] mean and std.dev: (390.07, 311.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1917)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 542836 sequences (77004503 bp) in 1.340 CPU sec, 1.345 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (99, 280481, 31, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 379, 1167)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3139)
[M::mem_pestat] mean and std.dev: (644.98, 625.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4125)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 222, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 659)
[M::mem_pestat] mean and std.dev: (245.90, 121.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 828)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (103, 535, 1982)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5740)
[M::mem_pestat] mean and std.dev: (827.52, 1180.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7619)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 350, 717)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1789)
[M::mem_pestat] mean and std.dev: (457.88, 394.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2325)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704342 reads in 180.824 CPU sec, 5.746 real sec
sorting block 83, #reads = 1063720 mem = 536878808 peak = 1127165952
[M::mem_process_seqs] Processed 704394 reads in 207.900 CPU sec, 6.628 real sec
sorting block 84, #reads = 1063200 mem = 536880519 peak = 1127165952
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 215804, 32, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 454, 706)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1742)
[M::mem_pestat] mean and std.dev: (442.05, 289.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2260)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 222, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (246.26, 122.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 831)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 398, 1170)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3116)
[M::mem_pestat] mean and std.dev: (571.24, 459.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4089)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (278, 424, 998)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2438)
[M::mem_pestat] mean and std.dev: (705.07, 649.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3302)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (95, 280393, 67, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 271, 886)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2312)
[M::mem_pestat] mean and std.dev: (506.14, 542.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3025)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 222, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 662)
[M::mem_pestat] mean and std.dev: (246.97, 122.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 832)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (371, 968, 1713)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4397)
[M::mem_pestat] mean and std.dev: (1021.89, 843.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5739)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 407, 1306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3504)
[M::mem_pestat] mean and std.dev: (776.28, 781.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4603)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 542836 reads in 177.886 CPU sec, 5.746 real sec
[M::mem_process_seqs] Processed 704548 reads in 207.654 CPU sec, 6.718 real sec
sorting block 85, #reads = 1065635 mem = 536880034 peak = 1127165952
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000c06f2
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: INTEL(R) XEON(R) PLATINUM 8559C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 91149976
overall: 71105843200 mem 16367.563 user 314.878 sys 544.283 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1136_3WJ-T1-TDNA-1_A23MHWWLT4_1.L005\tPU:L005\tSM:1136_3WJ-T1-TDNA-1_A23MHWWLT4_1\tLB:1136_3WJ-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1136_3WJ-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1136_3WJ-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 544.324 sec; CPU: 16682.445 sec
sorting block 86, #reads = 211265 mem = 106367283 peak = 1127165952
uniq header count 1
merging 87 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000c06f2
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: INTEL(R) XEON(R) PLATINUM 8559C
threads: 31 max 192
algo: util-sort
license: sentieon:util=1
output file size: 5541661694
output reads: 92022377
bam_mem_sort: 87 calls 44.108 user 0.781 sys 45.036 real
bam_write: 87 calls 26.659 user 1.584 sys 28.391 real
execute: 1 calls 27.636 user 1.533 sys 583.424 real
merge_files: 1 calls 27.625 user 1.492 sys 38.974 real
parse_chunk: 1380 calls 73.654 user 16.761 sys 91.462 real
read_chunk: 3740 calls 35.785 user 28.552 sys 498.725 real
sort_block: 1 calls 25.822 user 28.111 sys 483.642 real
write_chunk: 2358 calls 27.275 user 1.283 sys 38.096 real
overall: 3351252992 mem 1515.954 user 60.055 sys 583.447 real
ls: cannot access '*.cram': No such file or directory