This software is licensed to bgold@natera.com by Sentieon Inc.
cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1136_253-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 1846.765 CPU sec, 71.815 real sec
[M::process] read 687480 sequences (100000148 bp) in 1.556 CPU sec, 1.560 real sec...
[M::process] read 686472 sequences (100000131 bp) in 1.740 CPU sec, 1.751 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 279663, 10, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 279, 530)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1220)
[M::mem_pestat] mean and std.dev: (362.36, 248.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1565)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 294, 421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 881)
[M::mem_pestat] mean and std.dev: (316.85, 156.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1111)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (335, 982, 1325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3305)
[M::mem_pestat] mean and std.dev: (845.78, 496.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4295)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 244, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 611)
[M::mem_pestat] mean and std.dev: (243.05, 101.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 753)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 686060 sequences (100000131 bp) in 1.639 CPU sec, 1.695 real sec...
[M::process] read 685334 sequences (100000086 bp) in 1.860 CPU sec, 1.929 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 278953, 18, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 299, 566)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1346)
[M::mem_pestat] mean and std.dev: (284.71, 173.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1736)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 299, 426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 892)
[M::mem_pestat] mean and std.dev: (321.08, 158.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1125)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 1073, 1467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4039)
[M::mem_pestat] mean and std.dev: (971.28, 883.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5325)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 322, 967)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2545)
[M::mem_pestat] mean and std.dev: (497.29, 400.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3334)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 687480 reads in 211.255 CPU sec, 6.772 real sec
[M::mem_process_seqs] Processed 686472 reads in 143.409 CPU sec, 4.661 real sec
sorting block 0, #reads = 1070884 mem = 536881283 peak = 595673088
[M::process] read 685244 sequences (100000210 bp) in 2.645 CPU sec, 2.862 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 279336, 13, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 294, 716)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1756)
[M::mem_pestat] mean and std.dev: (358.07, 227.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2276)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 302, 427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 891)
[M::mem_pestat] mean and std.dev: (322.59, 157.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1123)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (324, 454, 858)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1926)
[M::mem_pestat] mean and std.dev: (500.25, 345.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2460)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 338, 425)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 839)
[M::mem_pestat] mean and std.dev: (304.69, 107.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1046)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 684496 sequences (100000085 bp) in 1.864 CPU sec, 1.872 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 279542, 11, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 350, 493)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1083)
[M::mem_pestat] mean and std.dev: (339.88, 212.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1378)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 304, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 896)
[M::mem_pestat] mean and std.dev: (324.40, 158.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1129)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (301, 1580, 6497)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 18889)
[M::mem_pestat] mean and std.dev: (2374.55, 2611.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 25085)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 429, 852)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2110)
[M::mem_pestat] mean and std.dev: (500.77, 383.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2739)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 686060 reads in 204.183 CPU sec, 6.498 real sec
[M::mem_process_seqs] Processed 685334 reads in 231.351 CPU sec, 7.421 real sec
sorting block 1, #reads = 1070961 mem = 536878961 peak = 723075072
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 279034, 16, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 325, 433)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 879)
[M::mem_pestat] mean and std.dev: (292.28, 102.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1102)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 307, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 909)
[M::mem_pestat] mean and std.dev: (327.37, 159.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1146)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (949, 1234, 3269)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7909)
[M::mem_pestat] mean and std.dev: (1930.88, 1787.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10229)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (286, 372, 815)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1873)
[M::mem_pestat] mean and std.dev: (488.03, 348.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2402)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683962 sequences (100000067 bp) in 2.528 CPU sec, 2.732 real sec...
[M::process] read 683868 sequences (100000036 bp) in 1.954 CPU sec, 1.994 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 278332, 8, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 452, 491)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1097)
[M::mem_pestat] mean and std.dev: (344.26, 199.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1400)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 309, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 908)
[M::mem_pestat] mean and std.dev: (328.84, 159.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1144)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 284, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 769)
[M::mem_pestat] mean and std.dev: (257.60, 163.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 979)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 685244 reads in 212.104 CPU sec, 6.831 real sec
[M::mem_process_seqs] Processed 684496 reads in 145.634 CPU sec, 4.676 real sec
sorting block 2, #reads = 1070733 mem = 536880007 peak = 770637824
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 278396, 16, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 326, 674)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1574)
[M::mem_pestat] mean and std.dev: (433.94, 330.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2024)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 311, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 907)
[M::mem_pestat] mean and std.dev: (330.09, 159.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1142)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (318, 513, 555)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1029)
[M::mem_pestat] mean and std.dev: (396.33, 161.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1266)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (271, 425, 636)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1366)
[M::mem_pestat] mean and std.dev: (412.83, 180.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1731)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683630 sequences (100000089 bp) in 2.837 CPU sec, 3.511 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 278473, 12, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (274, 348, 1333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3451)
[M::mem_pestat] mean and std.dev: (636.61, 643.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4510)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 313, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 914)
[M::mem_pestat] mean and std.dev: (331.86, 160.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1151)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (385, 1201, 1994)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5212)
[M::mem_pestat] mean and std.dev: (940.90, 661.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6821)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 284, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1053)
[M::mem_pestat] mean and std.dev: (297.51, 151.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1347)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683066 sequences (100000018 bp) in 2.104 CPU sec, 2.414 real sec...
[M::mem_process_seqs] Processed 683962 reads in 216.672 CPU sec, 7.143 real sec
sorting block 3, #reads = 1069818 mem = 536879680 peak = 855056384
[M::mem_process_seqs] Processed 683868 reads in 149.182 CPU sec, 4.922 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 278019, 22, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 295, 741)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1721)
[M::mem_pestat] mean and std.dev: (446.24, 360.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2211)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 316, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 927)
[M::mem_pestat] mean and std.dev: (335.25, 162.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1168)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (526, 1306, 2439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6265)
[M::mem_pestat] mean and std.dev: (1699.86, 1671.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8387)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 332, 565)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1227)
[M::mem_pestat] mean and std.dev: (367.59, 168.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1558)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 4, #reads = 1070447 mem = 536878326 peak = 864088064
[M::process] read 683196 sequences (100000043 bp) in 2.682 CPU sec, 3.207 real sec...
[M::process] read 682824 sequences (100000133 bp) in 1.942 CPU sec, 2.053 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 278046, 12, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 298, 694)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1798)
[M::mem_pestat] mean and std.dev: (409.37, 388.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2350)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 319, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 933)
[M::mem_pestat] mean and std.dev: (337.55, 162.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1175)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 2178, 5235)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 15311)
[M::mem_pestat] mean and std.dev: (2389.25, 2396.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 20349)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 431, 571)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1275)
[M::mem_pestat] mean and std.dev: (360.23, 205.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1627)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683630 reads in 225.715 CPU sec, 7.688 real sec
[M::mem_process_seqs] Processed 683066 reads in 157.000 CPU sec, 5.383 real sec
sorting block 5, #reads = 1068667 mem = 536880250 peak = 864088064
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 278181, 17, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 382, 1360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3650)
[M::mem_pestat] mean and std.dev: (923.35, 1014.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4982)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 317, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 923)
[M::mem_pestat] mean and std.dev: (336.03, 161.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1162)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (528, 774, 1579)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3681)
[M::mem_pestat] mean and std.dev: (957.44, 568.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4732)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 379, 1345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3647)
[M::mem_pestat] mean and std.dev: (715.61, 718.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4798)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683086 sequences (100000019 bp) in 3.069 CPU sec, 3.625 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 278140, 9, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 324, 808)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2014)
[M::mem_pestat] mean and std.dev: (492.26, 411.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2617)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 317, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 921)
[M::mem_pestat] mean and std.dev: (336.13, 161.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1159)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (305, 376, 429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (57, 677)
[M::mem_pestat] mean and std.dev: (314.97, 106.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 801)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683196 reads in 218.600 CPU sec, 7.218 real sec
[M::process] read 682886 sequences (100000217 bp) in 2.168 CPU sec, 2.472 real sec...
[M::mem_process_seqs] Processed 682824 reads in 149.650 CPU sec, 4.930 real sec
sorting block 6, #reads = 1069157 mem = 536879878 peak = 864088064
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 278075, 9, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 457, 534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1160)
[M::mem_pestat] mean and std.dev: (347.47, 169.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1473)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 317, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 922)
[M::mem_pestat] mean and std.dev: (334.96, 160.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1161)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 405, 637)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1423)
[M::mem_pestat] mean and std.dev: (442.20, 279.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1816)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683134 sequences (100000178 bp) in 2.903 CPU sec, 3.627 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 278003, 5, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 327, 656)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1654)
[M::mem_pestat] mean and std.dev: (345.83, 227.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2153)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 318, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 932)
[M::mem_pestat] mean and std.dev: (337.20, 162.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1174)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 237, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (253.44, 110.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 860)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682834 sequences (100000268 bp) in 2.162 CPU sec, 2.208 real sec...
[M::mem_process_seqs] Processed 683086 reads in 218.036 CPU sec, 7.103 real sec
sorting block 7, #reads = 1068675 mem = 536885024 peak = 864088064
[M::mem_process_seqs] Processed 682886 reads in 150.719 CPU sec, 4.906 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 278263, 12, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (109, 244, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 898)
[M::mem_pestat] mean and std.dev: (207.67, 96.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1161)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 314, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 913)
[M::mem_pestat] mean and std.dev: (333.71, 161.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1149)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (93, 266, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 873)
[M::mem_pestat] mean and std.dev: (215.36, 122.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1133)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 241, 675)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1583)
[M::mem_pestat] mean and std.dev: (349.57, 251.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2037)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682482 sequences (100000232 bp) in 3.044 CPU sec, 3.437 real sec...
sorting block 8, #reads = 1067855 mem = 536879829 peak = 870805504
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 278044, 4, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 236, 499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1113)
[M::mem_pestat] mean and std.dev: (316.70, 234.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1420)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 318, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 926)
[M::mem_pestat] mean and std.dev: (336.59, 161.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1166)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 253, 411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 897)
[M::mem_pestat] mean and std.dev: (266.61, 146.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1140)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682378 sequences (100000121 bp) in 2.351 CPU sec, 2.538 real sec...
[M::mem_process_seqs] Processed 683134 reads in 217.359 CPU sec, 7.103 real sec
[M::mem_process_seqs] Processed 682834 reads in 150.040 CPU sec, 4.894 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 277932, 6, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 402, 674)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1610)
[M::mem_pestat] mean and std.dev: (456.20, 289.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2078)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 320, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 934)
[M::mem_pestat] mean and std.dev: (339.12, 162.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1176)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 309, 1038)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2606)
[M::mem_pestat] mean and std.dev: (624.36, 509.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3390)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 9, #reads = 1069107 mem = 536878126 peak = 870805504
[M::process] read 682402 sequences (100000041 bp) in 2.563 CPU sec, 3.131 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 277855, 7, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 209, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 551)
[M::mem_pestat] mean and std.dev: (198.55, 48.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 676)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 318, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 913)
[M::mem_pestat] mean and std.dev: (335.76, 159.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1148)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 234, 650)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1522)
[M::mem_pestat] mean and std.dev: (395.85, 265.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1958)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682300 sequences (100000203 bp) in 2.207 CPU sec, 2.275 real sec...
[M::mem_process_seqs] Processed 682482 reads in 216.057 CPU sec, 7.133 real sec
[M::mem_process_seqs] Processed 682378 reads in 150.368 CPU sec, 5.011 real sec
sorting block 10, #reads = 1068446 mem = 536880685 peak = 870805504
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 277260, 19, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 286, 520)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1102)
[M::mem_pestat] mean and std.dev: (321.59, 210.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1393)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 318, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 919)
[M::mem_pestat] mean and std.dev: (336.57, 160.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1156)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (275, 444, 3012)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8486)
[M::mem_pestat] mean and std.dev: (1470.39, 1669.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11223)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 313, 485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1089)
[M::mem_pestat] mean and std.dev: (342.87, 219.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1391)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682406 sequences (100000149 bp) in 3.373 CPU sec, 4.066 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 277446, 9, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 315, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 975)
[M::mem_pestat] mean and std.dev: (305.19, 162.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1235)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 315, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 903)
[M::mem_pestat] mean and std.dev: (333.32, 158.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1135)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 266, 416)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 836)
[M::mem_pestat] mean and std.dev: (282.41, 127.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1046)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682402 reads in 223.173 CPU sec, 7.382 real sec
[M::process] read 682086 sequences (100000288 bp) in 2.454 CPU sec, 2.478 real sec...
[M::mem_process_seqs] Processed 682300 reads in 154.559 CPU sec, 5.114 real sec
sorting block 11, #reads = 1068425 mem = 536878354 peak = 870805504
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 277682, 19, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 280, 396)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 812)
[M::mem_pestat] mean and std.dev: (269.08, 131.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1020)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 316, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 912)
[M::mem_pestat] mean and std.dev: (334.55, 158.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1147)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 195, 619)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1541)
[M::mem_pestat] mean and std.dev: (359.61, 352.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2002)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 395, 999)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2525)
[M::mem_pestat] mean and std.dev: (546.67, 451.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3288)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682684 sequences (100000239 bp) in 3.082 CPU sec, 3.835 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 277694, 15, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 410, 810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2044)
[M::mem_pestat] mean and std.dev: (473.53, 431.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2661)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 319, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 914)
[M::mem_pestat] mean and std.dev: (336.35, 158.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1149)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (606, 905, 2670)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6798)
[M::mem_pestat] mean and std.dev: (1489.40, 1602.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8862)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 397, 541)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1169)
[M::mem_pestat] mean and std.dev: (375.83, 200.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1483)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682406 reads in 223.563 CPU sec, 7.558 real sec
sorting block 12, #reads = 1067943 mem = 536882872 peak = 870805504
[M::mem_process_seqs] Processed 682086 reads in 155.203 CPU sec, 5.225 real sec
[M::process] read 682880 sequences (100000284 bp) in 2.526 CPU sec, 2.742 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 277930, 23, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 329, 596)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1436)
[M::mem_pestat] mean and std.dev: (359.58, 284.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1856)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 315, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 902)
[M::mem_pestat] mean and std.dev: (332.88, 157.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1134)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (605, 880, 1789)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4157)
[M::mem_pestat] mean and std.dev: (1074.82, 901.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5341)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 272, 484)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1026)
[M::mem_pestat] mean and std.dev: (366.09, 202.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1297)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 13, #reads = 1066527 mem = 536881245 peak = 870805504
[M::process] read 682728 sequences (100000262 bp) in 3.239 CPU sec, 3.899 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 278216, 18, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 269, 474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1012)
[M::mem_pestat] mean and std.dev: (309.25, 144.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1281)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 313, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 904)
[M::mem_pestat] mean and std.dev: (332.14, 158.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1137)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (402, 735, 1231)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2889)
[M::mem_pestat] mean and std.dev: (757.50, 409.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3718)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 281, 385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 827)
[M::mem_pestat] mean and std.dev: (242.94, 98.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1048)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682684 reads in 223.200 CPU sec, 7.674 real sec
[M::mem_process_seqs] Processed 682880 reads in 155.990 CPU sec, 5.497 real sec
[M::process] read 682412 sequences (100000210 bp) in 2.907 CPU sec, 3.523 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 277451, 13, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 348, 595)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1409)
[M::mem_pestat] mean and std.dev: (323.03, 198.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1816)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 315, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 914)
[M::mem_pestat] mean and std.dev: (333.97, 159.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1150)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (571, 917, 998)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1852)
[M::mem_pestat] mean and std.dev: (744.42, 421.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2431)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 352, 684)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1626)
[M::mem_pestat] mean and std.dev: (448.76, 354.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2097)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 14, #reads = 1066624 mem = 536881185 peak = 870805504
[M::process] read 682750 sequences (100000192 bp) in 2.825 CPU sec, 3.317 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 277810, 8, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 323, 464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1050)
[M::mem_pestat] mean and std.dev: (264.10, 122.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1343)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 316, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 915)
[M::mem_pestat] mean and std.dev: (334.76, 159.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1151)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 286, 599)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1441)
[M::mem_pestat] mean and std.dev: (381.69, 330.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1862)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682728 reads in 222.853 CPU sec, 7.582 real sec
[M::mem_process_seqs] Processed 682412 reads in 154.027 CPU sec, 5.386 real sec
[M::process] read 682476 sequences (100000083 bp) in 2.814 CPU sec, 3.211 real sec...
sorting block 15, #reads = 1067320 mem = 536880417 peak = 870805504
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 277696, 20, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 262, 575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1443)
[M::mem_pestat] mean and std.dev: (329.49, 267.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1877)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 315, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 914)
[M::mem_pestat] mean and std.dev: (334.47, 160.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1150)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 322, 2958)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8488)
[M::mem_pestat] mean and std.dev: (1313.42, 1527.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11253)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 223, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 563)
[M::mem_pestat] mean and std.dev: (212.00, 63.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 694)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682482 sequences (100000174 bp) in 3.005 CPU sec, 3.615 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 277265, 7, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 251, 417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 891)
[M::mem_pestat] mean and std.dev: (282.32, 123.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1128)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 318, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 919)
[M::mem_pestat] mean and std.dev: (337.01, 161.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1156)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 270, 571)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1349)
[M::mem_pestat] mean and std.dev: (319.49, 226.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1738)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682750 reads in 221.031 CPU sec, 7.407 real sec
[M::mem_process_seqs] Processed 682476 reads in 155.343 CPU sec, 5.205 real sec
[M::process] read 681862 sequences (100000232 bp) in 2.735 CPU sec, 3.078 real sec...
sorting block 16, #reads = 1066526 mem = 536879124 peak = 870805504
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 277892, 13, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 260, 410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 798)
[M::mem_pestat] mean and std.dev: (263.71, 91.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 992)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 320, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 934)
[M::mem_pestat] mean and std.dev: (339.57, 164.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1176)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (427, 534, 2689)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7213)
[M::mem_pestat] mean and std.dev: (1074.00, 1026.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9475)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 297, 587)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1287)
[M::mem_pestat] mean and std.dev: (376.90, 230.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1637)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683388 sequences (100000247 bp) in 2.856 CPU sec, 3.263 real sec...
sorting block 17, #reads = 1066404 mem = 536878909 peak = 878665728
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 277579, 8, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (263, 350, 521)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1037)
[M::mem_pestat] mean and std.dev: (344.64, 178.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1295)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 323, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 939)
[M::mem_pestat] mean and std.dev: (342.74, 165.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1182)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 477, 602)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1346)
[M::mem_pestat] mean and std.dev: (480.00, 283.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1718)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682482 reads in 222.147 CPU sec, 7.348 real sec
[M::mem_process_seqs] Processed 681862 reads in 153.663 CPU sec, 5.077 real sec
[M::process] read 686714 sequences (100000065 bp) in 2.958 CPU sec, 3.209 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 278273, 4, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 449, 588)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1310)
[M::mem_pestat] mean and std.dev: (394.61, 216.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1671)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 315, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 930)
[M::mem_pestat] mean and std.dev: (336.05, 164.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1172)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (266, 337, 1059)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2645)
[M::mem_pestat] mean and std.dev: (590.62, 546.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3438)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 18, #reads = 1066702 mem = 536880774 peak = 878665728
[M::process] read 685574 sequences (100000030 bp) in 3.091 CPU sec, 3.362 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 279605, 22, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 339, 474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 920)
[M::mem_pestat] mean and std.dev: (351.33, 187.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1143)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 298, 423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 883)
[M::mem_pestat] mean and std.dev: (319.16, 156.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1113)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (252, 806, 989)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2463)
[M::mem_pestat] mean and std.dev: (665.22, 431.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3200)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 509, 636)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1430)
[M::mem_pestat] mean and std.dev: (461.81, 293.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1827)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683388 reads in 223.547 CPU sec, 7.266 real sec
[M::mem_process_seqs] Processed 686714 reads in 152.849 CPU sec, 4.887 real sec
[M::process] read 685206 sequences (100000280 bp) in 2.784 CPU sec, 2.892 real sec...
sorting block 19, #reads = 1066766 mem = 536880947 peak = 878665728
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 278600, 6, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 238, 530)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1278)
[M::mem_pestat] mean and std.dev: (361.37, 314.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1652)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 303, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 896)
[M::mem_pestat] mean and std.dev: (324.20, 158.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1129)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 313, 1221)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3257)
[M::mem_pestat] mean and std.dev: (541.15, 510.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4275)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 684708 sequences (100000035 bp) in 2.999 CPU sec, 3.295 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 278774, 4, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 274, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 954)
[M::mem_pestat] mean and std.dev: (325.55, 163.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1200)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 306, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 897)
[M::mem_pestat] mean and std.dev: (325.49, 158.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1130)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 265, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1049)
[M::mem_pestat] mean and std.dev: (304.97, 222.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1351)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 685574 reads in 210.475 CPU sec, 6.801 real sec
[M::mem_process_seqs] Processed 685206 reads in 147.604 CPU sec, 4.709 real sec
[M::process] read 684460 sequences (100000219 bp) in 3.040 CPU sec, 3.225 real sec...
sorting block 20, #reads = 1073642 mem = 536877209 peak = 878665728
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 278974, 12, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 405, 1419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3899)
[M::mem_pestat] mean and std.dev: (560.85, 489.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5139)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 307, 429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 887)
[M::mem_pestat] mean and std.dev: (325.16, 156.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1116)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (450, 1306, 6524)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 18672)
[M::mem_pestat] mean and std.dev: (2339.92, 2519.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 24746)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (323, 460, 2044)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5486)
[M::mem_pestat] mean and std.dev: (1280.64, 1575.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7581)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 684016 sequences (100000162 bp) in 3.475 CPU sec, 3.736 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 278880, 11, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 308, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 926)
[M::mem_pestat] mean and std.dev: (269.88, 108.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1167)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 308, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 891)
[M::mem_pestat] mean and std.dev: (326.57, 157.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1121)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (479, 1961, 3641)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9965)
[M::mem_pestat] mean and std.dev: (1950.73, 1574.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13127)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 336, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 922)
[M::mem_pestat] mean and std.dev: (323.35, 170.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1168)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684708 reads in 211.782 CPU sec, 6.962 real sec
sorting block 21, #reads = 1071687 mem = 536877422 peak = 878665728
[M::mem_process_seqs] Processed 684460 reads in 149.110 CPU sec, 4.862 real sec
[M::process] read 684026 sequences (100000233 bp) in 3.058 CPU sec, 3.311 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 278899, 12, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 330, 704)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1698)
[M::mem_pestat] mean and std.dev: (374.88, 256.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2195)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 311, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 901)
[M::mem_pestat] mean and std.dev: (329.27, 158.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1134)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (2567, 2567, 9581)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 23609)
[M::mem_pestat] mean and std.dev: (4580.33, 3845.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 30623)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 276, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 686)
[M::mem_pestat] mean and std.dev: (274.96, 101.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 849)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 22, #reads = 1071683 mem = 536880226 peak = 878665728
[M::process] read 683664 sequences (100000121 bp) in 3.224 CPU sec, 3.516 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 278876, 10, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 274, 637)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1441)
[M::mem_pestat] mean and std.dev: (358.06, 261.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1843)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 312, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 904)
[M::mem_pestat] mean and std.dev: (329.51, 158.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1138)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (269, 1196, 2569)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7169)
[M::mem_pestat] mean and std.dev: (1653.30, 1437.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9469)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 279, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 944)
[M::mem_pestat] mean and std.dev: (301.43, 165.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1188)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684016 reads in 209.325 CPU sec, 6.764 real sec
[M::mem_process_seqs] Processed 684026 reads in 146.383 CPU sec, 4.665 real sec
[M::process] read 683544 sequences (100000108 bp) in 3.424 CPU sec, 3.717 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 278091, 11, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 179, 280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 560)
[M::mem_pestat] mean and std.dev: (183.53, 66.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 700)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 315, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 915)
[M::mem_pestat] mean and std.dev: (332.56, 159.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1152)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (887, 1174, 1505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2741)
[M::mem_pestat] mean and std.dev: (1128.55, 488.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3359)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 300, 393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 779)
[M::mem_pestat] mean and std.dev: (294.69, 109.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 972)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 23, #reads = 1071035 mem = 536884424 peak = 878665728
[M::process] read 683506 sequences (100000129 bp) in 3.365 CPU sec, 3.637 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 278148, 19, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 465, 788)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1972)
[M::mem_pestat] mean and std.dev: (512.60, 398.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2564)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 314, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 909)
[M::mem_pestat] mean and std.dev: (332.16, 159.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1144)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (298, 357, 1434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3706)
[M::mem_pestat] mean and std.dev: (632.81, 647.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4842)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 325, 499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1073)
[M::mem_pestat] mean and std.dev: (332.04, 119.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1360)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683664 reads in 211.724 CPU sec, 6.861 real sec
[M::mem_process_seqs] Processed 683544 reads in 146.370 CPU sec, 4.700 real sec
sorting block 24, #reads = 1070519 mem = 536880744 peak = 878665728
[M::process] read 683284 sequences (100000152 bp) in 3.331 CPU sec, 3.649 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 278413, 9, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (246, 346, 413)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 747)
[M::mem_pestat] mean and std.dev: (330.57, 116.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 914)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 316, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 916)
[M::mem_pestat] mean and std.dev: (333.74, 160.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1153)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 356, 565)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1357)
[M::mem_pestat] mean and std.dev: (436.76, 330.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1760)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 278343, 11, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 213, 525)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1189)
[M::mem_pestat] mean and std.dev: (324.32, 238.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1521)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 318, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 917)
[M::mem_pestat] mean and std.dev: (334.80, 160.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1154)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (374, 481, 4275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12077)
[M::mem_pestat] mean and std.dev: (1735.73, 1747.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 15978)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 491, 729)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1713)
[M::mem_pestat] mean and std.dev: (446.44, 216.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2205)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682944 sequences (100000016 bp) in 3.336 CPU sec, 3.657 real sec...
[M::mem_process_seqs] Processed 683506 reads in 206.396 CPU sec, 6.652 real sec
[M::mem_process_seqs] Processed 683284 reads in 143.936 CPU sec, 4.574 real sec
sorting block 25, #reads = 1071560 mem = 536878337 peak = 878665728
[M::process] read 682702 sequences (100000169 bp) in 3.254 CPU sec, 3.467 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 278538, 17, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 216, 561)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1329)
[M::mem_pestat] mean and std.dev: (324.90, 211.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1713)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 319, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 921)
[M::mem_pestat] mean and std.dev: (336.24, 160.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1159)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (114, 437, 1232)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3468)
[M::mem_pestat] mean and std.dev: (661.82, 691.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4586)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 399, 751)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1815)
[M::mem_pestat] mean and std.dev: (529.83, 381.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2347)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 26, #reads = 1070139 mem = 536881061 peak = 878665728
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 277940, 4, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 240, 510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1114)
[M::mem_pestat] mean and std.dev: (359.29, 303.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1573)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 682756 sequences (100000290 bp) in 3.373 CPU sec, 3.617 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (208, 319, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 916)
[M::mem_pestat] mean and std.dev: (336.41, 160.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1152)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (264, 457, 1882)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5118)
[M::mem_pestat] mean and std.dev: (930.00, 935.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6736)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682944 reads in 203.817 CPU sec, 6.517 real sec
[M::mem_process_seqs] Processed 682702 reads in 141.590 CPU sec, 4.481 real sec
[M::process] read 682714 sequences (100000062 bp) in 2.919 CPU sec, 3.075 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 278719, 15, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (297, 705, 1317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3357)
[M::mem_pestat] mean and std.dev: (817.07, 658.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4377)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 318, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 915)
[M::mem_pestat] mean and std.dev: (335.27, 159.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1151)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (780, 1169, 4620)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12300)
[M::mem_pestat] mean and std.dev: (1988.33, 1791.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16140)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 338, 500)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1130)
[M::mem_pestat] mean and std.dev: (377.14, 267.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1445)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 27, #reads = 1070089 mem = 536879585 peak = 878665728
[M::process] read 682406 sequences (100000249 bp) in 2.849 CPU sec, 3.007 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 277602, 19, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 197, 516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1256)
[M::mem_pestat] mean and std.dev: (240.15, 183.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1626)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 322, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 928)
[M::mem_pestat] mean and std.dev: (338.80, 161.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1168)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (562, 963, 1391)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3049)
[M::mem_pestat] mean and std.dev: (1089.63, 808.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4325)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (258, 396, 596)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1272)
[M::mem_pestat] mean and std.dev: (380.56, 214.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1610)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682756 reads in 205.796 CPU sec, 6.564 real sec
[M::process] read 682700 sequences (100000154 bp) in 1.893 CPU sec, 1.906 real sec...
[M::mem_process_seqs] Processed 682714 reads in 139.366 CPU sec, 4.404 real sec
sorting block 28, #reads = 1069826 mem = 536879223 peak = 878665728
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 277611, 11, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 246, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 752)
[M::mem_pestat] mean and std.dev: (273.21, 151.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 953)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 319, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 913)
[M::mem_pestat] mean and std.dev: (336.18, 159.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1148)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (93, 342, 474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1236)
[M::mem_pestat] mean and std.dev: (273.30, 215.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1617)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (289, 416, 717)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1573)
[M::mem_pestat] mean and std.dev: (500.98, 376.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2008)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682652 sequences (100000026 bp) in 2.966 CPU sec, 3.092 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 278008, 11, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 326, 807)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2077)
[M::mem_pestat] mean and std.dev: (356.00, 299.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2712)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 318, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 910)
[M::mem_pestat] mean and std.dev: (335.42, 159.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1144)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (115, 786, 2876)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8398)
[M::mem_pestat] mean and std.dev: (1138.45, 1242.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11159)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 313, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 645)
[M::mem_pestat] mean and std.dev: (276.48, 89.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 782)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682252 sequences (100000066 bp) in 2.230 CPU sec, 2.227 real sec...
[M::mem_process_seqs] Processed 682406 reads in 196.139 CPU sec, 6.213 real sec
sorting block 29, #reads = 1069083 mem = 536879444 peak = 878665728
[M::mem_process_seqs] Processed 682700 reads in 135.592 CPU sec, 4.300 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 278241, 23, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 191, 989)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2653)
[M::mem_pestat] mean and std.dev: (443.32, 444.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3485)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 320, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 922)
[M::mem_pestat] mean and std.dev: (337.24, 161.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1160)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (484, 786, 1632)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3928)
[M::mem_pestat] mean and std.dev: (1020.70, 815.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5076)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 270, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 567)
[M::mem_pestat] mean and std.dev: (237.69, 102.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 690)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682094 sequences (100000003 bp) in 2.872 CPU sec, 3.022 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 277616, 13, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 171, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 796)
[M::mem_pestat] mean and std.dev: (200.44, 87.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1014)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 319, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 915)
[M::mem_pestat] mean and std.dev: (337.55, 160.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1150)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (519, 830, 869)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1569)
[M::mem_pestat] mean and std.dev: (585.27, 334.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1925)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 475, 570)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1226)
[M::mem_pestat] mean and std.dev: (420.43, 216.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1554)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682788 sequences (100000269 bp) in 2.260 CPU sec, 2.257 real sec...
[M::mem_process_seqs] Processed 682652 reads in 198.704 CPU sec, 6.304 real sec
sorting block 30, #reads = 1069133 mem = 536879066 peak = 878665728
[M::mem_process_seqs] Processed 682252 reads in 135.311 CPU sec, 4.283 real sec
sorting block 31, #reads = 1067983 mem = 536877604 peak = 970010624
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 277334, 19, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 339, 480)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 938)
[M::mem_pestat] mean and std.dev: (352.75, 172.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1167)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 321, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 918)
[M::mem_pestat] mean and std.dev: (338.39, 160.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1154)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (110, 513, 904)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2492)
[M::mem_pestat] mean and std.dev: (638.00, 566.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3286)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 402, 777)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1835)
[M::mem_pestat] mean and std.dev: (452.06, 327.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2364)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683046 sequences (100000187 bp) in 3.119 CPU sec, 3.318 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 277215, 17, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 262, 575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1253)
[M::mem_pestat] mean and std.dev: (318.90, 165.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1592)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 315, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 912)
[M::mem_pestat] mean and std.dev: (334.98, 160.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1147)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (727, 1011, 2661)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6529)
[M::mem_pestat] mean and std.dev: (1231.24, 883.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8463)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 347, 650)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1442)
[M::mem_pestat] mean and std.dev: (434.32, 295.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1838)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682388 sequences (100000289 bp) in 2.219 CPU sec, 2.218 real sec...
[M::mem_process_seqs] Processed 682094 reads in 202.491 CPU sec, 6.414 real sec
[M::mem_process_seqs] Processed 682788 reads in 141.129 CPU sec, 4.477 real sec
sorting block 32, #reads = 1067371 mem = 536879619 peak = 970010624
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 278264, 16, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 453, 693)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1537)
[M::mem_pestat] mean and std.dev: (425.71, 218.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1959)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 313, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 913)
[M::mem_pestat] mean and std.dev: (333.45, 160.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1149)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (254, 706, 975)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2417)
[M::mem_pestat] mean and std.dev: (662.69, 480.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3138)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (259, 454, 815)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1927)
[M::mem_pestat] mean and std.dev: (429.00, 269.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2483)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682544 sequences (100000298 bp) in 3.727 CPU sec, 4.117 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 277693, 13, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (257, 322, 379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (13, 623)
[M::mem_pestat] mean and std.dev: (289.64, 88.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 745)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 318, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 916)
[M::mem_pestat] mean and std.dev: (335.99, 160.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1152)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 332, 1641)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4635)
[M::mem_pestat] mean and std.dev: (729.38, 802.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6132)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (259, 426, 477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 913)
[M::mem_pestat] mean and std.dev: (371.86, 168.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1131)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683046 reads in 205.702 CPU sec, 6.516 real sec
[M::process] read 682448 sequences (100000185 bp) in 2.470 CPU sec, 2.484 real sec...
sorting block 33, #reads = 1066933 mem = 536879750 peak = 970010624
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 277883, 7, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 251, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1001)
[M::mem_pestat] mean and std.dev: (263.98, 140.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1272)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 315, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 912)
[M::mem_pestat] mean and std.dev: (334.57, 159.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1147)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 326, 537)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1171)
[M::mem_pestat] mean and std.dev: (340.11, 184.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1488)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682420 sequences (100000184 bp) in 2.597 CPU sec, 2.617 real sec...
[M::mem_process_seqs] Processed 682544 reads in 118.625 CPU sec, 3.941 real sec
[M::mem_process_seqs] Processed 682388 reads in 290.919 CPU sec, 9.402 real sec
sorting block 34, #reads = 1067958 mem = 536880971 peak = 970010624
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 278027, 19, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 272, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 981)
[M::mem_pestat] mean and std.dev: (301.13, 182.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1252)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 317, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 915)
[M::mem_pestat] mean and std.dev: (335.38, 160.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1151)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (590, 870, 1679)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3857)
[M::mem_pestat] mean and std.dev: (914.59, 620.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4946)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (279, 376, 599)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1239)
[M::mem_pestat] mean and std.dev: (436.09, 262.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1559)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682674 sequences (100000084 bp) in 2.678 CPU sec, 2.797 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 277828, 4, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 258, 422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 940)
[M::mem_pestat] mean and std.dev: (260.76, 135.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1199)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 316, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 914)
[M::mem_pestat] mean and std.dev: (334.53, 159.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1150)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 279, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 655)
[M::mem_pestat] mean and std.dev: (262.96, 97.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 805)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682470 sequences (100000048 bp) in 2.149 CPU sec, 2.148 real sec...
[M::mem_process_seqs] Processed 682448 reads in 222.114 CPU sec, 7.047 real sec
[M::mem_process_seqs] Processed 682420 reads in 136.597 CPU sec, 4.322 real sec
sorting block 35, #reads = 1067475 mem = 536881097 peak = 970010624
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 278427, 10, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 331, 552)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1234)
[M::mem_pestat] mean and std.dev: (369.25, 215.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1575)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 315, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 912)
[M::mem_pestat] mean and std.dev: (334.84, 160.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1147)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (437, 1208, 2156)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5594)
[M::mem_pestat] mean and std.dev: (1127.33, 776.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7313)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 280, 629)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1415)
[M::mem_pestat] mean and std.dev: (425.36, 307.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1808)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682602 sequences (100000149 bp) in 2.882 CPU sec, 3.016 real sec...
[M::process] read 682358 sequences (100000281 bp) in 1.999 CPU sec, 1.997 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 277846, 17, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 279, 729)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1691)
[M::mem_pestat] mean and std.dev: (334.55, 208.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2172)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 317, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 913)
[M::mem_pestat] mean and std.dev: (336.42, 161.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1148)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (302, 1929, 3946)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11234)
[M::mem_pestat] mean and std.dev: (2116.71, 2080.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14878)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 185, 569)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1357)
[M::mem_pestat] mean and std.dev: (306.65, 249.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1751)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682674 reads in 198.103 CPU sec, 6.278 real sec
sorting block 36, #reads = 1067863 mem = 536879559 peak = 970010624
[M::mem_process_seqs] Processed 682470 reads in 137.074 CPU sec, 4.354 real sec
sorting block 37, #reads = 1067354 mem = 536878616 peak = 970010624
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 277887, 15, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (132, 259, 1092)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3012)
[M::mem_pestat] mean and std.dev: (603.47, 663.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3972)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 319, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 933)
[M::mem_pestat] mean and std.dev: (338.69, 163.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1175)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (322, 460, 1136)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2764)
[M::mem_pestat] mean and std.dev: (562.15, 624.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3578)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 414, 548)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1230)
[M::mem_pestat] mean and std.dev: (383.09, 215.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1571)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682340 sequences (100000120 bp) in 2.891 CPU sec, 3.008 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 277765, 9, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (284, 405, 536)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1040)
[M::mem_pestat] mean and std.dev: (367.45, 167.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1292)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 320, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 940)
[M::mem_pestat] mean and std.dev: (340.75, 165.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1184)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 247, 612)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1444)
[M::mem_pestat] mean and std.dev: (356.30, 261.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1860)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 686280 sequences (100000010 bp) in 2.420 CPU sec, 2.415 real sec...
[M::mem_process_seqs] Processed 682602 reads in 199.011 CPU sec, 6.300 real sec
[M::mem_process_seqs] Processed 682358 reads in 138.646 CPU sec, 4.392 real sec
sorting block 38, #reads = 1066931 mem = 536878415 peak = 970010624
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 278072, 8, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (246, 408, 529)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1095)
[M::mem_pestat] mean and std.dev: (335.87, 150.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1378)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 322, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 943)
[M::mem_pestat] mean and std.dev: (342.05, 166.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1188)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 279, 479)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1005)
[M::mem_pestat] mean and std.dev: (339.29, 217.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1268)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 686052 sequences (100000296 bp) in 3.183 CPU sec, 3.280 real sec...
[M::process] read 685248 sequences (100000146 bp) in 2.150 CPU sec, 2.148 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 278476, 9, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 269, 589)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1287)
[M::mem_pestat] mean and std.dev: (340.16, 221.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1636)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 299, 423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 881)
[M::mem_pestat] mean and std.dev: (319.93, 156.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1110)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 351, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 860)
[M::mem_pestat] mean and std.dev: (365.23, 171.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1062)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682340 reads in 201.049 CPU sec, 6.357 real sec
[M::mem_process_seqs] Processed 686280 reads in 136.542 CPU sec, 4.327 real sec
sorting block 39, #reads = 1066614 mem = 536878188 peak = 970010624
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 279162, 15, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 1346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3712)
[M::mem_pestat] mean and std.dev: (675.12, 847.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4895)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 301, 425)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 883)
[M::mem_pestat] mean and std.dev: (321.16, 156.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1112)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (572, 899, 1208)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2480)
[M::mem_pestat] mean and std.dev: (765.08, 427.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3116)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 313, 670)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1568)
[M::mem_pestat] mean and std.dev: (429.42, 354.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2017)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 684726 sequences (100000251 bp) in 2.860 CPU sec, 2.956 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 279172, 19, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 350, 953)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2499)
[M::mem_pestat] mean and std.dev: (603.48, 611.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3272)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 305, 428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 888)
[M::mem_pestat] mean and std.dev: (323.86, 156.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1118)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (126, 531, 1858)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5322)
[M::mem_pestat] mean and std.dev: (909.42, 889.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7054)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 219, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 612)
[M::mem_pestat] mean and std.dev: (238.06, 80.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 758)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 684488 sequences (100000125 bp) in 2.390 CPU sec, 2.384 real sec...
[M::mem_process_seqs] Processed 686052 reads in 192.290 CPU sec, 6.079 real sec
sorting block 40, #reads = 1070958 mem = 536880377 peak = 970010624
[M::mem_process_seqs] Processed 685248 reads in 133.001 CPU sec, 4.207 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 278840, 9, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 287, 495)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1081)
[M::mem_pestat] mean and std.dev: (324.03, 175.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1374)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 308, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 896)
[M::mem_pestat] mean and std.dev: (326.62, 157.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1128)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 354, 524)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1138)
[M::mem_pestat] mean and std.dev: (399.78, 237.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1445)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 684034 sequences (100000288 bp) in 2.912 CPU sec, 2.990 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 278995, 9, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (299, 389, 614)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1244)
[M::mem_pestat] mean and std.dev: (406.20, 227.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1559)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 309, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 894)
[M::mem_pestat] mean and std.dev: (327.46, 158.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1125)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 518, 929)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2317)
[M::mem_pestat] mean and std.dev: (553.00, 456.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3011)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683970 sequences (100000197 bp) in 2.330 CPU sec, 2.322 real sec...
[M::mem_process_seqs] Processed 684726 reads in 194.012 CPU sec, 6.131 real sec
sorting block 41, #reads = 1070316 mem = 536877985 peak = 970010624
[M::mem_process_seqs] Processed 684488 reads in 131.863 CPU sec, 4.165 real sec
sorting block 42, #reads = 1071291 mem = 536882021 peak = 970010624
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 278631, 12, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 349, 619)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1379)
[M::mem_pestat] mean and std.dev: (404.18, 270.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1759)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 312, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 904)
[M::mem_pestat] mean and std.dev: (330.17, 158.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1138)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (666, 1154, 4588)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12432)
[M::mem_pestat] mean and std.dev: (2530.50, 2816.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16354)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 307, 640)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1498)
[M::mem_pestat] mean and std.dev: (376.73, 275.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1927)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683582 sequences (100000289 bp) in 2.781 CPU sec, 2.871 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 278451, 14, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 220, 1142)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3052)
[M::mem_pestat] mean and std.dev: (559.70, 654.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4007)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 314, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 906)
[M::mem_pestat] mean and std.dev: (331.61, 159.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1140)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (117, 491, 920)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2526)
[M::mem_pestat] mean and std.dev: (522.57, 420.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3329)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 414, 723)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1799)
[M::mem_pestat] mean and std.dev: (522.29, 386.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2337)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683374 sequences (100000294 bp) in 2.320 CPU sec, 2.317 real sec...
[M::mem_process_seqs] Processed 684034 reads in 190.972 CPU sec, 6.046 real sec
[M::mem_process_seqs] Processed 683970 reads in 132.362 CPU sec, 4.194 real sec
sorting block 43, #reads = 1069641 mem = 536880232 peak = 970010624
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 278947, 14, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 254, 850)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2142)
[M::mem_pestat] mean and std.dev: (487.15, 469.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2788)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 315, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 909)
[M::mem_pestat] mean and std.dev: (332.22, 159.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1144)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (711, 711, 878)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (377, 1212)
[M::mem_pestat] mean and std.dev: (730.22, 52.28)
[M::mem_pestat] low and high boundaries for proper pairs: (210, 1379)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 344, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 964)
[M::mem_pestat] mean and std.dev: (313.81, 181.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1210)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683244 sequences (100000063 bp) in 3.214 CPU sec, 3.295 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 278451, 22, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 265, 389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 831)
[M::mem_pestat] mean and std.dev: (244.74, 110.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1052)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 317, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 919)
[M::mem_pestat] mean and std.dev: (335.08, 161.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1157)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (102, 499, 657)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1767)
[M::mem_pestat] mean and std.dev: (393.10, 358.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2322)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 337, 710)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1670)
[M::mem_pestat] mean and std.dev: (451.68, 348.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2150)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683066 sequences (100000070 bp) in 2.310 CPU sec, 2.314 real sec...
[M::mem_process_seqs] Processed 683582 reads in 189.739 CPU sec, 5.985 real sec
[M::mem_process_seqs] Processed 683374 reads in 130.478 CPU sec, 4.120 real sec
sorting block 44, #reads = 1069444 mem = 536881939 peak = 970010624
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 278767, 13, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 256, 383)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 811)
[M::mem_pestat] mean and std.dev: (253.61, 104.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1025)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 319, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 929)
[M::mem_pestat] mean and std.dev: (336.96, 162.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1170)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (901, 1899, 2412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5434)
[M::mem_pestat] mean and std.dev: (1606.08, 911.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6945)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 329, 536)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1234)
[M::mem_pestat] mean and std.dev: (360.77, 241.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1583)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682412 sequences (100000056 bp) in 2.827 CPU sec, 2.897 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 278569, 15, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 222, 429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 921)
[M::mem_pestat] mean and std.dev: (262.86, 146.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1167)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 321, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 934)
[M::mem_pestat] mean and std.dev: (339.55, 163.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1176)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (417, 739, 739)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1383)
[M::mem_pestat] mean and std.dev: (504.69, 361.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1949)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 250, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 591)
[M::mem_pestat] mean and std.dev: (249.40, 79.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 720)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682348 sequences (100000226 bp) in 2.360 CPU sec, 2.354 real sec...
[M::mem_process_seqs] Processed 683244 reads in 188.126 CPU sec, 5.945 real sec
sorting block 45, #reads = 1070010 mem = 536877825 peak = 970010624
[M::mem_process_seqs] Processed 683066 reads in 130.728 CPU sec, 4.125 real sec
sorting block 46, #reads = 1070014 mem = 536877217 peak = 970010624
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 278164, 11, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 314, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1025)
[M::mem_pestat] mean and std.dev: (324.70, 184.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1303)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 321, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 926)
[M::mem_pestat] mean and std.dev: (339.35, 162.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1165)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1364, 2179, 5909)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 14999)
[M::mem_pestat] mean and std.dev: (3728.00, 2951.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 19544)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 309, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 588)
[M::mem_pestat] mean and std.dev: (290.18, 99.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 707)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682296 sequences (100000106 bp) in 3.161 CPU sec, 3.226 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 278037, 13, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 301, 835)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2073)
[M::mem_pestat] mean and std.dev: (426.33, 324.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2692)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 323, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 927)
[M::mem_pestat] mean and std.dev: (340.58, 163.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1166)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (70, 693, 1454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4222)
[M::mem_pestat] mean and std.dev: (604.18, 493.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5606)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 367, 589)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1379)
[M::mem_pestat] mean and std.dev: (320.31, 191.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1774)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682236 sequences (100000259 bp) in 2.320 CPU sec, 2.326 real sec...
[M::mem_process_seqs] Processed 682412 reads in 187.679 CPU sec, 5.920 real sec
[M::mem_process_seqs] Processed 682348 reads in 126.113 CPU sec, 3.985 real sec
sorting block 47, #reads = 1069756 mem = 536881607 peak = 970010624
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 277923, 14, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 377, 1017)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2607)
[M::mem_pestat] mean and std.dev: (487.04, 373.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3402)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 323, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 927)
[M::mem_pestat] mean and std.dev: (340.11, 162.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1166)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1509, 1509, 1969)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (589, 2889)
[M::mem_pestat] mean and std.dev: (1525.80, 369.97)
[M::mem_pestat] low and high boundaries for proper pairs: (46, 3349)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 327, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 918)
[M::mem_pestat] mean and std.dev: (284.58, 108.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1162)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681966 sequences (100000117 bp) in 2.840 CPU sec, 2.914 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 277582, 6, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 291, 592)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1352)
[M::mem_pestat] mean and std.dev: (288.92, 149.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1732)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 323, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 930)
[M::mem_pestat] mean and std.dev: (340.62, 163.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1170)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (312, 519, 1155)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2841)
[M::mem_pestat] mean and std.dev: (706.91, 565.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3684)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681724 sequences (100000268 bp) in 2.320 CPU sec, 2.325 real sec...
[M::mem_process_seqs] Processed 682296 reads in 191.155 CPU sec, 6.043 real sec
[M::mem_process_seqs] Processed 682236 reads in 131.617 CPU sec, 4.157 real sec
sorting block 48, #reads = 1069259 mem = 536877453 peak = 970010624
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 277571, 11, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 259, 478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1038)
[M::mem_pestat] mean and std.dev: (339.66, 227.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1318)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 323, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 928)
[M::mem_pestat] mean and std.dev: (340.89, 162.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1167)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 274, 4589)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13349)
[M::mem_pestat] mean and std.dev: (1683.27, 2245.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17729)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 368, 866)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2158)
[M::mem_pestat] mean and std.dev: (456.78, 333.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2804)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682098 sequences (100000081 bp) in 2.674 CPU sec, 2.754 real sec...
[M::process] read 682000 sequences (100000148 bp) in 1.810 CPU sec, 1.812 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 278220, 18, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 309, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 938)
[M::mem_pestat] mean and std.dev: (303.52, 125.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1186)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 324, 451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 929)
[M::mem_pestat] mean and std.dev: (341.66, 162.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1168)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 452, 804)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2098)
[M::mem_pestat] mean and std.dev: (424.71, 333.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2745)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 339, 485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1001)
[M::mem_pestat] mean and std.dev: (370.66, 199.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1259)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681966 reads in 190.985 CPU sec, 6.056 real sec
sorting block 49, #reads = 1069561 mem = 536878337 peak = 970010624
[M::mem_process_seqs] Processed 681724 reads in 131.250 CPU sec, 4.178 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 277517, 19, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 364, 659)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1495)
[M::mem_pestat] mean and std.dev: (452.48, 265.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1913)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 318, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 914)
[M::mem_pestat] mean and std.dev: (336.69, 160.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1149)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (666, 1210, 1270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2478)
[M::mem_pestat] mean and std.dev: (964.00, 518.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3082)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 252, 496)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1106)
[M::mem_pestat] mean and std.dev: (307.87, 200.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1411)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681826 sequences (100000005 bp) in 2.859 CPU sec, 2.923 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 277845, 18, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 250, 582)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1346)
[M::mem_pestat] mean and std.dev: (325.55, 231.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1728)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 319, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 920)
[M::mem_pestat] mean and std.dev: (338.39, 162.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1157)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (388, 486, 713)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1363)
[M::mem_pestat] mean and std.dev: (516.41, 212.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1688)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 339, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 850)
[M::mem_pestat] mean and std.dev: (346.98, 147.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1056)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682110 sequences (100000205 bp) in 2.330 CPU sec, 2.333 real sec...
[M::mem_process_seqs] Processed 682098 reads in 189.930 CPU sec, 5.998 real sec
sorting block 50, #reads = 1068435 mem = 536888538 peak = 970010624
[M::mem_process_seqs] Processed 682000 reads in 131.537 CPU sec, 4.161 real sec
sorting block 51, #reads = 1069614 mem = 536881137 peak = 1009094656
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 277874, 7, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 311, 1356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3712)
[M::mem_pestat] mean and std.dev: (610.32, 573.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4890)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 317, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 914)
[M::mem_pestat] mean and std.dev: (336.63, 160.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1149)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 434, 704)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1604)
[M::mem_pestat] mean and std.dev: (435.03, 262.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2054)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682678 sequences (100000001 bp) in 3.265 CPU sec, 3.347 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 277533, 16, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 265, 703)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1767)
[M::mem_pestat] mean and std.dev: (349.04, 258.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2299)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 317, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 916)
[M::mem_pestat] mean and std.dev: (336.69, 161.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1152)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (115, 721, 1071)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2983)
[M::mem_pestat] mean and std.dev: (747.94, 708.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3939)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 269, 486)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1114)
[M::mem_pestat] mean and std.dev: (283.86, 178.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1428)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682362 sequences (100000223 bp) in 2.350 CPU sec, 2.348 real sec...
[M::mem_process_seqs] Processed 681826 reads in 196.460 CPU sec, 6.203 real sec
[M::mem_process_seqs] Processed 682110 reads in 136.396 CPU sec, 4.314 real sec
sorting block 52, #reads = 1068935 mem = 536880435 peak = 1009094656
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 277447, 11, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 319, 552)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1240)
[M::mem_pestat] mean and std.dev: (403.51, 301.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1611)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 315, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 908)
[M::mem_pestat] mean and std.dev: (334.44, 160.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1142)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (344, 676, 2188)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5876)
[M::mem_pestat] mean and std.dev: (1175.45, 1076.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7720)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 271, 382)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 788)
[M::mem_pestat] mean and std.dev: (282.16, 133.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 991)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682398 sequences (100000013 bp) in 2.524 CPU sec, 2.602 real sec...
[M::process] read 682452 sequences (100000007 bp) in 1.890 CPU sec, 1.890 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 277667, 14, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (263, 329, 733)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1673)
[M::mem_pestat] mean and std.dev: (420.05, 270.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2143)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 316, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 909)
[M::mem_pestat] mean and std.dev: (334.96, 160.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1143)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (673, 1014, 1818)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4108)
[M::mem_pestat] mean and std.dev: (1187.93, 915.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5253)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 315, 404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 806)
[M::mem_pestat] mean and std.dev: (288.55, 131.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1007)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682678 reads in 196.873 CPU sec, 6.251 real sec
sorting block 53, #reads = 1067914 mem = 536878985 peak = 1009094656
[M::mem_process_seqs] Processed 682362 reads in 135.416 CPU sec, 4.314 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 277862, 5, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 337, 485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1113)
[M::mem_pestat] mean and std.dev: (327.63, 197.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1427)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 315, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 906)
[M::mem_pestat] mean and std.dev: (333.93, 159.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1139)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 304, 508)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1046)
[M::mem_pestat] mean and std.dev: (302.77, 141.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1315)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682574 sequences (100000277 bp) in 2.896 CPU sec, 2.997 real sec...
[M::process] read 682540 sequences (100000281 bp) in 2.330 CPU sec, 2.335 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 278122, 20, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 360, 499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1015)
[M::mem_pestat] mean and std.dev: (340.62, 136.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1273)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 314, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 909)
[M::mem_pestat] mean and std.dev: (334.49, 160.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1143)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (107, 344, 669)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1793)
[M::mem_pestat] mean and std.dev: (382.42, 275.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2355)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 292, 421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 835)
[M::mem_pestat] mean and std.dev: (354.35, 175.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1055)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682398 reads in 197.224 CPU sec, 6.236 real sec
sorting block 54, #reads = 1068812 mem = 536879741 peak = 1009094656
[M::mem_process_seqs] Processed 682452 reads in 135.900 CPU sec, 4.313 real sec
sorting block 55, #reads = 1068234 mem = 536879430 peak = 1009094656
[M::process] read 682336 sequences (100000265 bp) in 2.885 CPU sec, 2.958 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 277878, 7, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 282, 475)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1049)
[M::mem_pestat] mean and std.dev: (298.64, 160.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1336)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 316, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 912)
[M::mem_pestat] mean and std.dev: (335.60, 161.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1147)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 293, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1024)
[M::mem_pestat] mean and std.dev: (325.85, 185.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1301)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682120 sequences (100000056 bp) in 2.320 CPU sec, 2.329 real sec...
[M::mem_process_seqs] Processed 682540 reads in 114.735 CPU sec, 3.621 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 277777, 14, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 267, 585)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1319)
[M::mem_pestat] mean and std.dev: (406.06, 308.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1686)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 313, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 902)
[M::mem_pestat] mean and std.dev: (332.76, 159.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1134)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 1349, 9179)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 27223)
[M::mem_pestat] mean and std.dev: (3267.29, 3926.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 36245)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 242, 607)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1485)
[M::mem_pestat] mean and std.dev: (324.91, 221.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1924)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 278238, 14, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 247, 863)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2211)
[M::mem_pestat] mean and std.dev: (382.97, 362.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2885)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 317, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 921)
[M::mem_pestat] mean and std.dev: (336.95, 162.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1159)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (645, 1592, 2430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6000)
[M::mem_pestat] mean and std.dev: (1663.29, 1155.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7785)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 354, 516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1128)
[M::mem_pestat] mean and std.dev: (348.78, 180.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1434)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682128 sequences (100000221 bp) in 2.390 CPU sec, 2.396 real sec...
[M::mem_process_seqs] Processed 682574 reads in 300.316 CPU sec, 9.490 real sec
sorting block 56, #reads = 1067114 mem = 536878630 peak = 1009094656
[M::mem_process_seqs] Processed 682336 reads in 157.602 CPU sec, 5.014 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 277625, 8, 19)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 316, 559)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1265)
[M::mem_pestat] mean and std.dev: (360.20, 212.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1618)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 321, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 932)
[M::mem_pestat] mean and std.dev: (340.67, 164.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1173)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (298, 370, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 811)
[M::mem_pestat] mean and std.dev: (342.29, 109.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 982)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681928 sequences (100000193 bp) in 2.819 CPU sec, 2.953 real sec...
[M::process] read 682666 sequences (100000207 bp) in 1.770 CPU sec, 1.769 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 277994, 8, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 177, 263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 497)
[M::mem_pestat] mean and std.dev: (193.60, 78.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 614)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 320, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 934)
[M::mem_pestat] mean and std.dev: (340.32, 164.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1176)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (258, 367, 519)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1041)
[M::mem_pestat] mean and std.dev: (324.62, 130.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1302)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682120 reads in 188.395 CPU sec, 5.970 real sec
sorting block 57, #reads = 1068252 mem = 536880683 peak = 1009094656
[M::mem_process_seqs] Processed 682128 reads in 213.962 CPU sec, 6.802 real sec
sorting block 58, #reads = 1067691 mem = 536880025 peak = 1061912576
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 278052, 11, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 256, 491)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1119)
[M::mem_pestat] mean and std.dev: (321.08, 224.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1433)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 321, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 949)
[M::mem_pestat] mean and std.dev: (342.73, 168.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1196)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (296, 508, 646)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1346)
[M::mem_pestat] mean and std.dev: (419.90, 197.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1696)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (275, 384, 808)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1874)
[M::mem_pestat] mean and std.dev: (489.23, 281.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2407)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 686206 sequences (100000213 bp) in 3.151 CPU sec, 3.273 real sec...
[M::process] read 685340 sequences (100000254 bp) in 2.070 CPU sec, 2.071 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 278314, 12, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 226, 389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 793)
[M::mem_pestat] mean and std.dev: (264.93, 127.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 995)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 325, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 952)
[M::mem_pestat] mean and std.dev: (346.15, 169.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1199)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1113, 2484, 2484)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5226)
[M::mem_pestat] mean and std.dev: (1688.42, 1010.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6597)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 234, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 735)
[M::mem_pestat] mean and std.dev: (244.77, 98.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 919)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682666 reads in 191.944 CPU sec, 6.061 real sec
[M::mem_process_seqs] Processed 681928 reads in 217.795 CPU sec, 6.902 real sec
sorting block 59, #reads = 1066629 mem = 536878837 peak = 1061912576
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 279320, 13, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 366, 773)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2019)
[M::mem_pestat] mean and std.dev: (390.43, 280.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2642)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 300, 425)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 885)
[M::mem_pestat] mean and std.dev: (320.97, 157.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1115)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (450, 750, 2716)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7248)
[M::mem_pestat] mean and std.dev: (1385.92, 1076.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9514)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 306, 682)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1678)
[M::mem_pestat] mean and std.dev: (378.56, 302.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2176)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 684596 sequences (100000163 bp) in 2.818 CPU sec, 2.916 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 278349, 15, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 448, 684)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1680)
[M::mem_pestat] mean and std.dev: (450.21, 322.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2178)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 305, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 897)
[M::mem_pestat] mean and std.dev: (325.66, 159.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1130)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (66, 591, 1493)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4347)
[M::mem_pestat] mean and std.dev: (676.47, 669.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5774)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 458, 649)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1555)
[M::mem_pestat] mean and std.dev: (379.68, 201.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2008)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 684170 sequences (100000008 bp) in 2.350 CPU sec, 2.354 real sec...
[M::mem_process_seqs] Processed 686206 reads in 192.558 CPU sec, 6.081 real sec
sorting block 60, #reads = 1070589 mem = 536881765 peak = 1061912576
[M::mem_process_seqs] Processed 685340 reads in 131.166 CPU sec, 4.150 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 278673, 11, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (121, 196, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (209.73, 104.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 865)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 310, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 914)
[M::mem_pestat] mean and std.dev: (330.71, 162.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1152)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (422, 1440, 3037)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8267)
[M::mem_pestat] mean and std.dev: (1406.45, 1123.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10882)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 488, 1437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3879)
[M::mem_pestat] mean and std.dev: (466.56, 469.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5100)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683830 sequences (100000237 bp) in 2.534 CPU sec, 2.643 real sec...
[M::process] read 683362 sequences (100000101 bp) in 1.780 CPU sec, 1.778 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 278546, 12, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 390, 575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1301)
[M::mem_pestat] mean and std.dev: (396.47, 264.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1664)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 313, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 925)
[M::mem_pestat] mean and std.dev: (333.51, 162.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1166)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (97, 398, 1244)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3538)
[M::mem_pestat] mean and std.dev: (598.75, 527.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4685)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 271, 644)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1568)
[M::mem_pestat] mean and std.dev: (387.68, 288.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2030)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684596 reads in 187.343 CPU sec, 5.945 real sec
sorting block 61, #reads = 1072126 mem = 536878699 peak = 1061912576
[M::mem_process_seqs] Processed 684170 reads in 127.434 CPU sec, 4.057 real sec
sorting block 62, #reads = 1071880 mem = 536879887 peak = 1061912576
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 278380, 11, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 300, 513)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1165)
[M::mem_pestat] mean and std.dev: (350.48, 200.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1491)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 315, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 917)
[M::mem_pestat] mean and std.dev: (333.52, 161.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1155)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (2051, 2051, 4682)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9944)
[M::mem_pestat] mean and std.dev: (2588.18, 1589.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12575)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (268, 393, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 880)
[M::mem_pestat] mean and std.dev: (351.19, 141.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1084)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683358 sequences (100000154 bp) in 2.866 CPU sec, 2.959 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 278480, 8, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 229, 682)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1760)
[M::mem_pestat] mean and std.dev: (384.44, 374.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2299)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 314, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 907)
[M::mem_pestat] mean and std.dev: (332.87, 160.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1141)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (263, 276, 718)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1628)
[M::mem_pestat] mean and std.dev: (333.16, 165.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2083)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683130 sequences (100000087 bp) in 2.300 CPU sec, 2.299 real sec...
[M::mem_process_seqs] Processed 683830 reads in 184.660 CPU sec, 5.835 real sec
[M::mem_process_seqs] Processed 683362 reads in 126.493 CPU sec, 3.986 real sec
sorting block 63, #reads = 1072182 mem = 536880503 peak = 1061912576
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 278221, 19, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 381, 386)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 772)
[M::mem_pestat] mean and std.dev: (307.82, 120.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 965)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 317, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 923)
[M::mem_pestat] mean and std.dev: (335.72, 162.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1162)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (63, 684, 1084)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3126)
[M::mem_pestat] mean and std.dev: (734.84, 595.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4147)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 435, 611)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1485)
[M::mem_pestat] mean and std.dev: (356.07, 233.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1922)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683036 sequences (100000142 bp) in 2.926 CPU sec, 3.010 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 277779, 9, 15)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 271, 399)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 807)
[M::mem_pestat] mean and std.dev: (299.00, 172.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1011)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 319, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 933)
[M::mem_pestat] mean and std.dev: (338.55, 163.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1175)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (491, 535, 1332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3014)
[M::mem_pestat] mean and std.dev: (829.67, 626.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3855)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682936 sequences (100000110 bp) in 2.300 CPU sec, 2.304 real sec...
[M::mem_process_seqs] Processed 683358 reads in 188.606 CPU sec, 5.958 real sec
[M::mem_process_seqs] Processed 683130 reads in 129.661 CPU sec, 4.091 real sec
sorting block 64, #reads = 1071998 mem = 536880190 peak = 1061912576
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 277774, 12, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 284, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 937)
[M::mem_pestat] mean and std.dev: (285.43, 123.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1186)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 320, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 938)
[M::mem_pestat] mean and std.dev: (339.45, 164.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1182)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (79, 431, 859)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2419)
[M::mem_pestat] mean and std.dev: (451.27, 441.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3199)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (276, 350, 556)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1116)
[M::mem_pestat] mean and std.dev: (375.25, 184.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1396)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682524 sequences (100000163 bp) in 2.854 CPU sec, 2.936 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 278029, 30, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 299, 588)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1280)
[M::mem_pestat] mean and std.dev: (382.35, 256.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1626)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 321, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 943)
[M::mem_pestat] mean and std.dev: (340.99, 165.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1188)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (343, 355, 855)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1879)
[M::mem_pestat] mean and std.dev: (547.38, 344.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2391)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 284, 536)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1156)
[M::mem_pestat] mean and std.dev: (341.07, 204.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1466)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682392 sequences (100000180 bp) in 2.280 CPU sec, 2.282 real sec...
[M::mem_process_seqs] Processed 683036 reads in 189.162 CPU sec, 5.978 real sec
sorting block 65, #reads = 1070469 mem = 536878446 peak = 1061912576
[M::mem_process_seqs] Processed 682936 reads in 129.560 CPU sec, 4.097 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 277774, 9, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 402, 1428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3834)
[M::mem_pestat] mean and std.dev: (836.04, 752.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5037)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 323, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 944)
[M::mem_pestat] mean and std.dev: (342.19, 165.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1189)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 487, 639)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1469)
[M::mem_pestat] mean and std.dev: (450.81, 284.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1884)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682328 sequences (100000178 bp) in 3.190 CPU sec, 3.276 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 277872, 8, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (261, 332, 978)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2412)
[M::mem_pestat] mean and std.dev: (528.08, 422.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3129)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 324, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 944)
[M::mem_pestat] mean and std.dev: (342.90, 166.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1189)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 287, 565)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1259)
[M::mem_pestat] mean and std.dev: (290.29, 150.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1606)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682422 sequences (100000049 bp) in 2.340 CPU sec, 2.339 real sec...
[M::mem_process_seqs] Processed 682524 reads in 188.947 CPU sec, 5.958 real sec
sorting block 66, #reads = 1071106 mem = 536878443 peak = 1061912576
[M::mem_process_seqs] Processed 682392 reads in 129.229 CPU sec, 4.080 real sec
sorting block 67, #reads = 1071281 mem = 536877694 peak = 1061912576
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 278408, 8, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 297, 486)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1038)
[M::mem_pestat] mean and std.dev: (298.89, 131.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1314)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 325, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 940)
[M::mem_pestat] mean and std.dev: (342.91, 164.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1183)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 342, 1384)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3682)
[M::mem_pestat] mean and std.dev: (804.04, 822.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4831)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682120 sequences (100000301 bp) in 2.799 CPU sec, 2.878 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 278104, 12, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 307, 411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 791)
[M::mem_pestat] mean and std.dev: (286.36, 109.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 981)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 323, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 942)
[M::mem_pestat] mean and std.dev: (341.65, 164.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1186)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (283, 1351, 1921)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5197)
[M::mem_pestat] mean and std.dev: (830.00, 752.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6835)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (277, 425, 1262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3232)
[M::mem_pestat] mean and std.dev: (572.92, 495.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4217)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682036 sequences (100000238 bp) in 2.230 CPU sec, 2.227 real sec...
[M::mem_process_seqs] Processed 682328 reads in 189.630 CPU sec, 5.996 real sec
[M::mem_process_seqs] Processed 682422 reads in 128.997 CPU sec, 4.075 real sec
sorting block 68, #reads = 1070794 mem = 536888930 peak = 1061912576
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 277801, 17, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 491, 855)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2053)
[M::mem_pestat] mean and std.dev: (615.78, 456.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2652)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 322, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 932)
[M::mem_pestat] mean and std.dev: (340.68, 163.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1173)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (598, 1527, 9003)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 25813)
[M::mem_pestat] mean and std.dev: (2879.00, 3448.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 34218)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 346, 408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 786)
[M::mem_pestat] mean and std.dev: (303.75, 113.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 975)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681414 sequences (100000246 bp) in 3.033 CPU sec, 3.104 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 277876, 12, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 289, 383)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (276.90, 115.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 941)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 322, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 927)
[M::mem_pestat] mean and std.dev: (340.17, 162.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1166)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1181, 1352, 4025)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9713)
[M::mem_pestat] mean and std.dev: (2316.00, 1957.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12557)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 354, 420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 862)
[M::mem_pestat] mean and std.dev: (278.11, 106.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1083)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681972 sequences (100000164 bp) in 2.322 CPU sec, 2.329 real sec...
[M::mem_process_seqs] Processed 682120 reads in 189.468 CPU sec, 5.983 real sec
sorting block 69, #reads = 1069240 mem = 536890349 peak = 1061912576
[M::mem_process_seqs] Processed 682036 reads in 129.407 CPU sec, 4.087 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 277840, 10, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (296, 364, 655)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1373)
[M::mem_pestat] mean and std.dev: (521.26, 407.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2153)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 326, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 933)
[M::mem_pestat] mean and std.dev: (343.13, 162.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1173)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (95, 222, 780)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2150)
[M::mem_pestat] mean and std.dev: (365.50, 320.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2835)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (364, 386, 1082)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2518)
[M::mem_pestat] mean and std.dev: (555.62, 467.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3236)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682730 sequences (100000184 bp) in 2.877 CPU sec, 2.931 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 277427, 8, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 229, 421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 983)
[M::mem_pestat] mean and std.dev: (247.39, 147.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1264)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 322, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 930)
[M::mem_pestat] mean and std.dev: (340.70, 163.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1170)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 326, 542)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1132)
[M::mem_pestat] mean and std.dev: (371.45, 188.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1427)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682942 sequences (100000207 bp) in 2.360 CPU sec, 2.363 real sec...
[M::mem_process_seqs] Processed 681414 reads in 186.522 CPU sec, 5.882 real sec
sorting block 70, #reads = 1068294 mem = 536881242 peak = 1061912576
[M::mem_process_seqs] Processed 681972 reads in 130.037 CPU sec, 4.113 real sec
sorting block 71, #reads = 1068890 mem = 536880890 peak = 1061912576
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 277681, 10, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 346, 1210)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3278)
[M::mem_pestat] mean and std.dev: (516.70, 496.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4312)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 313, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 910)
[M::mem_pestat] mean and std.dev: (332.87, 159.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1145)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (368, 1205, 2509)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6791)
[M::mem_pestat] mean and std.dev: (1557.90, 1144.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8932)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 326, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 596)
[M::mem_pestat] mean and std.dev: (277.84, 93.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 725)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682538 sequences (100000126 bp) in 3.095 CPU sec, 3.150 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 278139, 9, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 336, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 955)
[M::mem_pestat] mean and std.dev: (311.82, 143.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1204)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 311, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 898)
[M::mem_pestat] mean and std.dev: (330.69, 158.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1129)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 353, 759)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1835)
[M::mem_pestat] mean and std.dev: (523.47, 448.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2373)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682710 sequences (100000266 bp) in 2.400 CPU sec, 2.408 real sec...
[M::mem_process_seqs] Processed 682730 reads in 195.832 CPU sec, 6.176 real sec
[M::mem_process_seqs] Processed 682942 reads in 220.776 CPU sec, 6.988 real sec
sorting block 72, #reads = 1068536 mem = 536879797 peak = 1061912576
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 277805, 16, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 322, 413)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 833)
[M::mem_pestat] mean and std.dev: (267.29, 105.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1043)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 314, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 908)
[M::mem_pestat] mean and std.dev: (333.33, 160.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1142)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (654, 1003, 2365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5787)
[M::mem_pestat] mean and std.dev: (1399.87, 1182.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7498)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 430, 915)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2375)
[M::mem_pestat] mean and std.dev: (662.21, 625.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3166)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682886 sequences (100000150 bp) in 2.952 CPU sec, 3.020 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 278058, 13, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 255, 520)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1170)
[M::mem_pestat] mean and std.dev: (279.74, 163.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1495)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 315, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 908)
[M::mem_pestat] mean and std.dev: (333.64, 159.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1142)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (663, 1427, 3061)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7857)
[M::mem_pestat] mean and std.dev: (1561.23, 1093.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10255)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 299, 489)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1033)
[M::mem_pestat] mean and std.dev: (335.88, 173.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1305)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682778 sequences (100000139 bp) in 2.350 CPU sec, 2.356 real sec...
[M::mem_process_seqs] Processed 682538 reads in 195.833 CPU sec, 6.189 real sec
[M::mem_process_seqs] Processed 682710 reads in 133.488 CPU sec, 4.215 real sec
sorting block 73, #reads = 1069516 mem = 536878110 peak = 1061912576
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 278581, 10, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 308, 541)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1175)
[M::mem_pestat] mean and std.dev: (311.91, 161.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1492)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 313, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 907)
[M::mem_pestat] mean and std.dev: (332.62, 159.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1141)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (445, 1045, 1998)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5104)
[M::mem_pestat] mean and std.dev: (789.00, 606.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6657)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 350, 995)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2521)
[M::mem_pestat] mean and std.dev: (472.50, 459.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3284)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682756 sequences (100000193 bp) in 2.987 CPU sec, 3.049 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 277798, 6, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 537, 880)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2194)
[M::mem_pestat] mean and std.dev: (564.40, 451.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2851)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 312, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 895)
[M::mem_pestat] mean and std.dev: (330.24, 157.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1125)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 352, 628)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1446)
[M::mem_pestat] mean and std.dev: (394.93, 263.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1855)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682684 sequences (100000028 bp) in 2.460 CPU sec, 2.465 real sec...
[M::mem_process_seqs] Processed 682886 reads in 194.534 CPU sec, 6.135 real sec
sorting block 74, #reads = 1069283 mem = 536880070 peak = 1061912576
[M::mem_process_seqs] Processed 682778 reads in 133.174 CPU sec, 4.215 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 278114, 19, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 333, 688)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1696)
[M::mem_pestat] mean and std.dev: (493.00, 421.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2200)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 312, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 898)
[M::mem_pestat] mean and std.dev: (331.59, 158.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1129)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (123, 639, 2615)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7599)
[M::mem_pestat] mean and std.dev: (1128.53, 1064.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10091)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 288, 495)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1095)
[M::mem_pestat] mean and std.dev: (331.81, 214.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1395)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682242 sequences (100000287 bp) in 3.264 CPU sec, 3.398 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 277828, 15, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 322, 478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1120)
[M::mem_pestat] mean and std.dev: (305.33, 176.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1441)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 315, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 911)
[M::mem_pestat] mean and std.dev: (334.15, 160.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1146)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (454, 675, 1765)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4387)
[M::mem_pestat] mean and std.dev: (1139.40, 1014.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5698)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 329, 477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 985)
[M::mem_pestat] mean and std.dev: (308.82, 125.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1239)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682460 sequences (100000094 bp) in 2.450 CPU sec, 2.449 real sec...
[M::mem_process_seqs] Processed 682756 reads in 197.359 CPU sec, 6.230 real sec
sorting block 75, #reads = 1069303 mem = 536878096 peak = 1061912576
[M::mem_process_seqs] Processed 682684 reads in 136.651 CPU sec, 4.310 real sec
sorting block 76, #reads = 1069236 mem = 536885354 peak = 1061912576
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 277587, 6, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 324, 702)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1810)
[M::mem_pestat] mean and std.dev: (455.49, 360.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2364)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 317, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 916)
[M::mem_pestat] mean and std.dev: (336.16, 160.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1152)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 389, 777)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1837)
[M::mem_pestat] mean and std.dev: (351.00, 191.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2367)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682312 sequences (100000033 bp) in 2.947 CPU sec, 3.020 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 277851, 15, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (272, 373, 750)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1706)
[M::mem_pestat] mean and std.dev: (465.88, 363.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2184)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 316, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 914)
[M::mem_pestat] mean and std.dev: (334.95, 160.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1150)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (374, 921, 1667)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4253)
[M::mem_pestat] mean and std.dev: (922.60, 736.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5546)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 196, 278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (17, 452)
[M::mem_pestat] mean and std.dev: (200.30, 65.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 539)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681002 sequences (100000035 bp) in 2.490 CPU sec, 2.493 real sec...
[M::mem_process_seqs] Processed 682242 reads in 202.097 CPU sec, 6.642 real sec
[M::mem_process_seqs] Processed 682460 reads in 137.771 CPU sec, 4.359 real sec
sorting block 77, #reads = 1067042 mem = 536879731 peak = 1061912576
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 278050, 8, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 346, 618)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1426)
[M::mem_pestat] mean and std.dev: (380.26, 209.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1830)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 318, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 922)
[M::mem_pestat] mean and std.dev: (337.68, 162.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1160)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (293, 371, 592)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1190)
[M::mem_pestat] mean and std.dev: (410.42, 234.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1489)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682308 sequences (100000161 bp) in 3.085 CPU sec, 3.206 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 277920, 13, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 289, 1277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3443)
[M::mem_pestat] mean and std.dev: (553.28, 494.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4526)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 329, 460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 950)
[M::mem_pestat] mean and std.dev: (347.82, 166.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1195)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (409, 1280, 1587)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3943)
[M::mem_pestat] mean and std.dev: (1063.92, 857.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5121)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 303, 642)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1472)
[M::mem_pestat] mean and std.dev: (411.31, 356.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1887)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682546 sequences (100000161 bp) in 2.420 CPU sec, 2.418 real sec...
[M::mem_process_seqs] Processed 682312 reads in 200.283 CPU sec, 6.338 real sec
sorting block 78, #reads = 1067632 mem = 536877185 peak = 1061912576
[M::mem_process_seqs] Processed 681002 reads in 140.848 CPU sec, 4.448 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 278484, 17, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 290, 646)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1594)
[M::mem_pestat] mean and std.dev: (317.10, 253.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2068)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 319, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 934)
[M::mem_pestat] mean and std.dev: (339.55, 164.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1176)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 484, 941)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2359)
[M::mem_pestat] mean and std.dev: (617.94, 442.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3068)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 534, 1502)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4102)
[M::mem_pestat] mean and std.dev: (1019.66, 1088.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5402)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 691718 sequences (100000226 bp) in 3.564 CPU sec, 3.656 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 278580, 10, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 280, 460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 950)
[M::mem_pestat] mean and std.dev: (299.79, 136.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1195)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 319, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 942)
[M::mem_pestat] mean and std.dev: (341.13, 167.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1187)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (743, 1475, 1615)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3359)
[M::mem_pestat] mean and std.dev: (1185.22, 494.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4231)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 341, 522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1166)
[M::mem_pestat] mean and std.dev: (354.63, 192.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1488)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682308 reads in 194.556 CPU sec, 6.135 real sec
[M::process] read 689732 sequences (100000043 bp) in 2.626 CPU sec, 2.626 real sec...
sorting block 79, #reads = 1067789 mem = 536878482 peak = 1061912576
[M::mem_process_seqs] Processed 682546 reads in 133.931 CPU sec, 4.228 real sec
sorting block 80, #reads = 1067966 mem = 536883799 peak = 1061912576
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 281570, 14, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 236, 570)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1372)
[M::mem_pestat] mean and std.dev: (368.48, 297.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1773)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 269, 395)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 831)
[M::mem_pestat] mean and std.dev: (297.10, 151.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1049)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (404, 753, 1578)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3926)
[M::mem_pestat] mean and std.dev: (845.62, 545.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5100)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 363, 818)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2102)
[M::mem_pestat] mean and std.dev: (486.91, 411.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2744)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 688776 sequences (100000133 bp) in 3.384 CPU sec, 3.490 real sec...
[M::process] read 687810 sequences (100000053 bp) in 2.180 CPU sec, 2.182 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 281570, 12, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 297, 801)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2029)
[M::mem_pestat] mean and std.dev: (493.73, 467.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2643)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 281, 413)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 873)
[M::mem_pestat] mean and std.dev: (308.46, 155.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1103)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 531, 1493)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4069)
[M::mem_pestat] mean and std.dev: (677.27, 613.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5357)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (268, 380, 1452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3820)
[M::mem_pestat] mean and std.dev: (519.04, 443.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5004)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 691718 reads in 216.986 CPU sec, 6.865 real sec
[M::mem_process_seqs] Processed 689732 reads in 145.754 CPU sec, 4.617 real sec
sorting block 81, #reads = 1066828 mem = 536881704 peak = 1061912576
[M::process] read 687308 sequences (100000145 bp) in 2.683 CPU sec, 2.757 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 281018, 12, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 326, 638)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1560)
[M::mem_pestat] mean and std.dev: (401.31, 326.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2021)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 287, 418)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 882)
[M::mem_pestat] mean and std.dev: (312.47, 156.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1114)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (69, 595, 1222)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3528)
[M::mem_pestat] mean and std.dev: (649.33, 634.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4681)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 342, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 872)
[M::mem_pestat] mean and std.dev: (328.07, 137.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1083)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 686138 sequences (100000122 bp) in 1.880 CPU sec, 1.882 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 280468, 7, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 315, 423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 927)
[M::mem_pestat] mean and std.dev: (301.48, 137.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1179)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 295, 429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 907)
[M::mem_pestat] mean and std.dev: (320.07, 159.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1146)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 355, 1293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3485)
[M::mem_pestat] mean and std.dev: (662.64, 658.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4581)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 280418, 16, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 397, 702)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1682)
[M::mem_pestat] mean and std.dev: (426.04, 289.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2172)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 291, 423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 893)
[M::mem_pestat] mean and std.dev: (316.04, 157.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1128)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (365, 654, 4388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12434)
[M::mem_pestat] mean and std.dev: (2234.25, 2287.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16457)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 283, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1000)
[M::mem_pestat] mean and std.dev: (242.26, 112.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1282)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 688776 reads in 293.013 CPU sec, 9.350 real sec
[M::mem_process_seqs] Processed 687308 reads in 224.616 CPU sec, 7.201 real sec
sorting block 82, #reads = 1068705 mem = 536882374 peak = 1061912576
[M::mem_process_seqs] Processed 687810 reads in 251.290 CPU sec, 8.065 real sec
[M::process] read 685602 sequences (100000181 bp) in 2.912 CPU sec, 3.041 real sec...
sorting block 83, #reads = 1067997 mem = 536879611 peak = 1061912576
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 280119, 8, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (286, 391, 564)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1120)
[M::mem_pestat] mean and std.dev: (402.16, 201.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1398)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 302, 433)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 909)
[M::mem_pestat] mean and std.dev: (323.86, 159.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1147)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (269, 448, 579)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1199)
[M::mem_pestat] mean and std.dev: (489.85, 309.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1729)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 684830 sequences (100000007 bp) in 2.097 CPU sec, 2.164 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 280085, 11, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 297, 919)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2469)
[M::mem_pestat] mean and std.dev: (414.78, 363.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3244)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 305, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 930)
[M::mem_pestat] mean and std.dev: (328.06, 162.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1175)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 551, 2438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6848)
[M::mem_pestat] mean and std.dev: (1348.00, 1601.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9053)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (140, 215, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (214.29, 88.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 686138 reads in 206.737 CPU sec, 6.565 real sec
[M::process] read 684600 sequences (100000187 bp) in 1.920 CPU sec, 1.915 real sec...
[M::mem_process_seqs] Processed 685602 reads in 142.321 CPU sec, 4.490 real sec
sorting block 84, #reads = 1068546 mem = 536878570 peak = 1061912576
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 279795, 11, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 249, 965)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2561)
[M::mem_pestat] mean and std.dev: (411.18, 414.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3359)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 310, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 940)
[M::mem_pestat] mean and std.dev: (332.52, 163.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1187)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (592, 1105, 1555)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3481)
[M::mem_pestat] mean and std.dev: (931.80, 608.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4444)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 395, 541)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1113)
[M::mem_pestat] mean and std.dev: (387.64, 198.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1399)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 685178 sequences (100000070 bp) in 2.944 CPU sec, 3.073 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 279198, 7, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 307, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 922)
[M::mem_pestat] mean and std.dev: (310.93, 166.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1150)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 313, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 950)
[M::mem_pestat] mean and std.dev: (335.24, 165.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1200)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 283, 638)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1474)
[M::mem_pestat] mean and std.dev: (396.79, 262.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1892)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 685056 sequences (100000204 bp) in 2.400 CPU sec, 2.395 real sec...
[M::mem_process_seqs] Processed 684830 reads in 202.644 CPU sec, 6.423 real sec
sorting block 85, #reads = 1068731 mem = 536879904 peak = 1061912576
[M::mem_process_seqs] Processed 684600 reads in 139.304 CPU sec, 4.406 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 279742, 20, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 429, 707)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1653)
[M::mem_pestat] mean and std.dev: (380.38, 214.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2126)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 311, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 945)
[M::mem_pestat] mean and std.dev: (332.64, 164.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1194)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (381, 1121, 1273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3057)
[M::mem_pestat] mean and std.dev: (1050.32, 785.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4192)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (270, 345, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 789)
[M::mem_pestat] mean and std.dev: (337.09, 148.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 962)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 685126 sequences (100000079 bp) in 2.826 CPU sec, 2.893 real sec...
[M::process] read 684716 sequences (100000259 bp) in 2.470 CPU sec, 2.463 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 279656, 12, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 301, 1217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3177)
[M::mem_pestat] mean and std.dev: (641.19, 640.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4157)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 308, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 930)
[M::mem_pestat] mean and std.dev: (329.93, 161.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1174)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (311, 675, 1804)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4790)
[M::mem_pestat] mean and std.dev: (746.25, 648.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6283)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 358, 627)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1407)
[M::mem_pestat] mean and std.dev: (353.90, 197.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1797)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 685178 reads in 210.497 CPU sec, 6.907 real sec
sorting block 86, #reads = 1068658 mem = 536878162 peak = 1061912576
[M::mem_process_seqs] Processed 685056 reads in 144.735 CPU sec, 4.709 real sec
sorting block 87, #reads = 1066953 mem = 536879731 peak = 1061912576
[M::process] read 684806 sequences (100000053 bp) in 2.479 CPU sec, 2.556 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 279253, 9, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (288, 363, 824)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1896)
[M::mem_pestat] mean and std.dev: (527.32, 389.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2432)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 308, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 927)
[M::mem_pestat] mean and std.dev: (329.41, 160.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1170)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 264, 491)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1007)
[M::mem_pestat] mean and std.dev: (314.74, 194.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1265)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 684496 sequences (100000142 bp) in 1.958 CPU sec, 1.954 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 279264, 10, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (123, 293, 830)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2244)
[M::mem_pestat] mean and std.dev: (444.06, 363.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2951)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 309, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 928)
[M::mem_pestat] mean and std.dev: (330.46, 161.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1171)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (116, 195, 879)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2405)
[M::mem_pestat] mean and std.dev: (606.90, 625.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3168)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 341, 404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 838)
[M::mem_pestat] mean and std.dev: (331.43, 161.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1055)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 279698, 18, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (103, 250, 388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 958)
[M::mem_pestat] mean and std.dev: (248.66, 141.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1243)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 309, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 928)
[M::mem_pestat] mean and std.dev: (330.12, 161.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1171)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (419, 640, 700)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1262)
[M::mem_pestat] mean and std.dev: (435.29, 239.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1543)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 287, 737)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1855)
[M::mem_pestat] mean and std.dev: (459.68, 400.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2414)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 685126 reads in 291.910 CPU sec, 9.426 real sec
[M::mem_process_seqs] Processed 684806 reads in 222.874 CPU sec, 7.138 real sec
sorting block 88, #reads = 1063953 mem = 536879682 peak = 1061912576
[M::mem_process_seqs] Processed 684716 reads in 247.127 CPU sec, 7.917 real sec
[M::process] read 685374 sequences (100000209 bp) in 3.288 CPU sec, 3.459 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 279393, 11, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 263, 643)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1513)
[M::mem_pestat] mean and std.dev: (288.28, 157.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1948)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 311, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 928)
[M::mem_pestat] mean and std.dev: (330.79, 160.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1171)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (34, 716, 5987)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 17893)
[M::mem_pestat] mean and std.dev: (2540.00, 2862.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 23846)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 235, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1082)
[M::mem_pestat] mean and std.dev: (278.93, 177.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1388)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 89, #reads = 1066653 mem = 536879175 peak = 1061912576
[M::process] read 684118 sequences (100000067 bp) in 2.562 CPU sec, 2.601 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 279309, 17, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 295, 408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 724)
[M::mem_pestat] mean and std.dev: (262.67, 85.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 882)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 304, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 916)
[M::mem_pestat] mean and std.dev: (326.22, 159.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1156)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (808, 845, 1705)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3499)
[M::mem_pestat] mean and std.dev: (1184.41, 767.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4396)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 309, 1316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3566)
[M::mem_pestat] mean and std.dev: (566.17, 532.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4691)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684496 reads in 198.412 CPU sec, 6.296 real sec
[M::mem_process_seqs] Processed 685374 reads in 137.024 CPU sec, 4.310 real sec
[M::process] read 683574 sequences (100000239 bp) in 2.818 CPU sec, 2.921 real sec...
sorting block 90, #reads = 1066707 mem = 536876845 peak = 1061912576
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 278704, 6, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 274, 751)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1845)
[M::mem_pestat] mean and std.dev: (494.88, 476.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2401)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 310, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 932)
[M::mem_pestat] mean and std.dev: (332.11, 162.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1176)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 335, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 858)
[M::mem_pestat] mean and std.dev: (341.61, 148.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1062)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 684166 sequences (100000104 bp) in 2.861 CPU sec, 2.932 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 278103, 8, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 249, 509)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1139)
[M::mem_pestat] mean and std.dev: (254.30, 106.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1454)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 312, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 925)
[M::mem_pestat] mean and std.dev: (332.29, 159.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1166)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 364, 558)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1310)
[M::mem_pestat] mean and std.dev: (380.68, 199.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1686)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683516 sequences (100000024 bp) in 2.170 CPU sec, 2.177 real sec...
[M::mem_process_seqs] Processed 684118 reads in 201.586 CPU sec, 6.372 real sec
sorting block 91, #reads = 1066165 mem = 536878069 peak = 1061912576
[M::mem_process_seqs] Processed 683574 reads in 139.093 CPU sec, 4.392 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 278415, 20, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 243, 451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1023)
[M::mem_pestat] mean and std.dev: (277.83, 166.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1309)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 310, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 927)
[M::mem_pestat] mean and std.dev: (331.48, 160.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1169)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (590, 1501, 1770)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4130)
[M::mem_pestat] mean and std.dev: (1134.45, 663.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5310)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 573, 621)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1465)
[M::mem_pestat] mean and std.dev: (385.54, 221.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1887)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683696 sequences (100000096 bp) in 3.314 CPU sec, 3.436 real sec...
[M::process] read 683410 sequences (100000065 bp) in 2.450 CPU sec, 2.452 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 278124, 20, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 255, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 875)
[M::mem_pestat] mean and std.dev: (294.10, 132.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1085)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 315, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 942)
[M::mem_pestat] mean and std.dev: (336.27, 163.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1188)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (108, 110, 1287)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3645)
[M::mem_pestat] mean and std.dev: (800.80, 952.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4824)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 324, 485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1075)
[M::mem_pestat] mean and std.dev: (312.40, 172.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1370)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684166 reads in 208.896 CPU sec, 6.600 real sec
sorting block 92, #reads = 1064212 mem = 536884156 peak = 1061912576
[M::mem_process_seqs] Processed 683516 reads in 236.190 CPU sec, 7.531 real sec
sorting block 93, #reads = 1064499 mem = 536881167 peak = 1061912576
[M::process] read 683276 sequences (100000258 bp) in 2.776 CPU sec, 2.841 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 278220, 13, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 281, 553)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1317)
[M::mem_pestat] mean and std.dev: (288.25, 201.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1699)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 311, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 931)
[M::mem_pestat] mean and std.dev: (333.27, 161.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1174)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (99, 747, 1635)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4707)
[M::mem_pestat] mean and std.dev: (903.38, 832.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6243)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 381, 481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1007)
[M::mem_pestat] mean and std.dev: (347.60, 181.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1270)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682922 sequences (100000065 bp) in 2.080 CPU sec, 2.071 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 277992, 15, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 321, 1508)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4196)
[M::mem_pestat] mean and std.dev: (602.82, 603.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5540)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 312, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 928)
[M::mem_pestat] mean and std.dev: (332.96, 161.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1170)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (795, 1121, 1952)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4266)
[M::mem_pestat] mean and std.dev: (1177.77, 664.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5423)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 365, 611)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1395)
[M::mem_pestat] mean and std.dev: (336.36, 150.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1787)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683696 reads in 216.264 CPU sec, 6.900 real sec
[M::mem_process_seqs] Processed 683410 reads in 144.899 CPU sec, 4.615 real sec
sorting block 94, #reads = 1063109 mem = 536882028 peak = 1061912576
[M::process] read 683094 sequences (100000298 bp) in 2.361 CPU sec, 2.447 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 277984, 18, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 372, 567)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1331)
[M::mem_pestat] mean and std.dev: (407.57, 321.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1713)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 314, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 930)
[M::mem_pestat] mean and std.dev: (334.86, 161.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1172)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (272, 734, 2751)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7709)
[M::mem_pestat] mean and std.dev: (1261.18, 1243.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10188)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 267, 955)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2435)
[M::mem_pestat] mean and std.dev: (448.56, 398.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3175)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682736 sequences (100000292 bp) in 1.850 CPU sec, 1.848 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 278013, 10, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (253, 387, 478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 928)
[M::mem_pestat] mean and std.dev: (308.10, 119.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1153)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 317, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 937)
[M::mem_pestat] mean and std.dev: (337.08, 162.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1181)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (429, 836, 1920)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4902)
[M::mem_pestat] mean and std.dev: (922.67, 862.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6393)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 273, 384)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 842)
[M::mem_pestat] mean and std.dev: (311.20, 158.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1071)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 278455, 14, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 266, 410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 954)
[M::mem_pestat] mean and std.dev: (273.04, 149.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1226)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 315, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 942)
[M::mem_pestat] mean and std.dev: (336.66, 163.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1188)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 339, 517)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1049)
[M::mem_pestat] mean and std.dev: (304.58, 156.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1315)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 370, 460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 924)
[M::mem_pestat] mean and std.dev: (365.55, 198.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1161)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683276 reads in 294.688 CPU sec, 9.524 real sec
sorting block 95, #reads = 1063650 mem = 536879627 peak = 1061912576
[M::mem_process_seqs] Processed 682922 reads in 225.942 CPU sec, 7.249 real sec
[M::mem_process_seqs] Processed 683094 reads in 248.726 CPU sec, 7.980 real sec
sorting block 96, #reads = 1063753 mem = 536881078 peak = 1061912576
[M::process] read 682490 sequences (100000151 bp) in 3.013 CPU sec, 3.155 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 278195, 13, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 235, 536)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1264)
[M::mem_pestat] mean and std.dev: (312.23, 227.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1628)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 319, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 952)
[M::mem_pestat] mean and std.dev: (339.90, 164.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1201)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1376, 2054, 4486)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10706)
[M::mem_pestat] mean and std.dev: (2806.46, 1667.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13816)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 415, 528)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1252)
[M::mem_pestat] mean and std.dev: (417.16, 324.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1716)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682624 sequences (100000016 bp) in 2.521 CPU sec, 2.551 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 278223, 11, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 402, 934)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2366)
[M::mem_pestat] mean and std.dev: (564.12, 527.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3082)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 320, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 957)
[M::mem_pestat] mean and std.dev: (342.16, 167.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1207)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (556, 565, 1844)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4420)
[M::mem_pestat] mean and std.dev: (1129.27, 628.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5708)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 262, 525)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1197)
[M::mem_pestat] mean and std.dev: (315.23, 227.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1533)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682736 reads in 207.727 CPU sec, 6.568 real sec
[M::mem_process_seqs] Processed 682490 reads in 142.672 CPU sec, 4.477 real sec
[M::process] read 694034 sequences (100000093 bp) in 2.667 CPU sec, 2.708 real sec...
sorting block 97, #reads = 1063336 mem = 536879679 peak = 1061912576
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 278213, 14, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 298, 697)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1687)
[M::mem_pestat] mean and std.dev: (414.21, 263.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2182)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 321, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 954)
[M::mem_pestat] mean and std.dev: (342.26, 167.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1203)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 1389, 1993)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5491)
[M::mem_pestat] mean and std.dev: (1361.69, 1315.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7240)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 346, 627)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1435)
[M::mem_pestat] mean and std.dev: (334.68, 223.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1839)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 691748 sequences (100000151 bp) in 2.681 CPU sec, 2.758 real sec...
[M::process] read 690602 sequences (100000104 bp) in 2.290 CPU sec, 2.289 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 282114, 10, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 305, 559)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1369)
[M::mem_pestat] mean and std.dev: (341.81, 258.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1774)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 258, 379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 793)
[M::mem_pestat] mean and std.dev: (285.84, 144.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1000)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (684, 866, 2570)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6342)
[M::mem_pestat] mean and std.dev: (1501.11, 1680.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8228)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 245, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (15, 495)
[M::mem_pestat] mean and std.dev: (242.94, 81.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 591)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682624 reads in 221.397 CPU sec, 7.020 real sec
sorting block 98, #reads = 1064594 mem = 536889504 peak = 1061912576
[M::mem_process_seqs] Processed 694034 reads in 157.242 CPU sec, 4.994 real sec
[M::process] read 689920 sequences (100000021 bp) in 3.014 CPU sec, 3.087 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281791, 5, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 275, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 849)
[M::mem_pestat] mean and std.dev: (272.75, 107.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1056)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 271, 395)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 829)
[M::mem_pestat] mean and std.dev: (296.49, 147.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1046)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 498, 1375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3729)
[M::mem_pestat] mean and std.dev: (628.73, 736.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4906)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 689244 sequences (100000065 bp) in 2.390 CPU sec, 2.391 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 281612, 15, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 276, 534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1230)
[M::mem_pestat] mean and std.dev: (338.31, 258.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1578)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 277, 401)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 841)
[M::mem_pestat] mean and std.dev: (300.96, 149.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1061)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (539, 721, 2522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6488)
[M::mem_pestat] mean and std.dev: (1676.73, 1536.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8471)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 253, 498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1130)
[M::mem_pestat] mean and std.dev: (303.25, 164.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1446)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 691748 reads in 227.508 CPU sec, 7.200 real sec
sorting block 99, #reads = 1060619 mem = 536880493 peak = 1061912576
[M::mem_process_seqs] Processed 690602 reads in 258.273 CPU sec, 8.204 real sec
sorting block 100, #reads = 1064074 mem = 536878573 peak = 1091665920
[M::process] read 689492 sequences (100000206 bp) in 2.786 CPU sec, 2.852 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 281454, 14, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 173, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 785)
[M::mem_pestat] mean and std.dev: (221.36, 145.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 997)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 280, 404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 848)
[M::mem_pestat] mean and std.dev: (303.02, 149.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1070)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (409, 618, 2189)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5749)
[M::mem_pestat] mean and std.dev: (1095.21, 976.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7529)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 323, 758)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1838)
[M::mem_pestat] mean and std.dev: (430.00, 316.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2378)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 688518 sequences (100000197 bp) in 2.410 CPU sec, 2.412 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 280472, 20, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 315, 881)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2321)
[M::mem_pestat] mean and std.dev: (487.03, 547.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3041)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 282, 405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 847)
[M::mem_pestat] mean and std.dev: (304.02, 148.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1068)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (544, 845, 1702)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4018)
[M::mem_pestat] mean and std.dev: (969.53, 641.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5176)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 291, 499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1069)
[M::mem_pestat] mean and std.dev: (272.28, 124.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1354)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 689920 reads in 235.303 CPU sec, 7.632 real sec
[M::mem_process_seqs] Processed 689244 reads in 262.224 CPU sec, 8.325 real sec
sorting block 101, #reads = 1062884 mem = 536882929 peak = 1091665920
[M::process] read 687648 sequences (100000185 bp) in 2.950 CPU sec, 3.023 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 280881, 8, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (269, 394, 598)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1256)
[M::mem_pestat] mean and std.dev: (384.27, 173.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1585)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 287, 412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 864)
[M::mem_pestat] mean and std.dev: (308.74, 150.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1090)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 289, 575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1337)
[M::mem_pestat] mean and std.dev: (308.58, 170.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1718)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 687144 sequences (100000012 bp) in 2.530 CPU sec, 2.536 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 281639, 15, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 416, 613)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1493)
[M::mem_pestat] mean and std.dev: (437.10, 311.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1933)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 282, 406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 850)
[M::mem_pestat] mean and std.dev: (304.29, 148.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1072)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (349, 448, 2050)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5452)
[M::mem_pestat] mean and std.dev: (865.23, 1074.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7153)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 283, 866)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2188)
[M::mem_pestat] mean and std.dev: (525.16, 457.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2849)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 688518 reads in 228.865 CPU sec, 7.243 real sec
sorting block 102, #reads = 1060991 mem = 536887462 peak = 1091665920
[M::mem_process_seqs] Processed 689492 reads in 255.755 CPU sec, 8.120 real sec
[M::process] read 687128 sequences (100000217 bp) in 3.134 CPU sec, 3.226 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281086, 19, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 386, 985)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2603)
[M::mem_pestat] mean and std.dev: (496.97, 453.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3412)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 291, 417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 873)
[M::mem_pestat] mean and std.dev: (312.39, 152.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1101)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 483, 9407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 27773)
[M::mem_pestat] mean and std.dev: (3071.11, 3879.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 36956)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 215, 284)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 558)
[M::mem_pestat] mean and std.dev: (232.74, 108.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 695)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 686594 sequences (100000019 bp) in 2.510 CPU sec, 2.511 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 280394, 10, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 326, 998)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2628)
[M::mem_pestat] mean and std.dev: (467.61, 416.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3443)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 294, 422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 886)
[M::mem_pestat] mean and std.dev: (316.18, 154.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1118)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (540, 781, 781)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (58, 1263)
[M::mem_pestat] mean and std.dev: (637.56, 280.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1761)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 328, 640)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1482)
[M::mem_pestat] mean and std.dev: (405.97, 300.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1903)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 687648 reads in 223.314 CPU sec, 7.073 real sec
sorting block 103, #reads = 1060439 mem = 536879759 peak = 1091665920
[M::mem_process_seqs] Processed 687144 reads in 243.993 CPU sec, 7.863 real sec
sorting block 104, #reads = 1063886 mem = 536879086 peak = 1091665920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 280597, 12, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 219, 420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 950)
[M::mem_pestat] mean and std.dev: (253.37, 128.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1215)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 295, 424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 890)
[M::mem_pestat] mean and std.dev: (317.32, 155.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1123)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (446, 680, 6226)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 17786)
[M::mem_pestat] mean and std.dev: (2360.75, 2953.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 23566)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 208, 392)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 832)
[M::mem_pestat] mean and std.dev: (221.58, 82.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1052)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 686064 sequences (100000162 bp) in 2.927 CPU sec, 2.994 real sec...
[M::mem_process_seqs] Processed 687128 reads in 127.496 CPU sec, 4.191 real sec
[M::process] read 686032 sequences (100000006 bp) in 2.770 CPU sec, 2.847 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 280319, 10, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 265, 2259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6449)
[M::mem_pestat] mean and std.dev: (704.74, 1055.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8544)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 298, 425)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 889)
[M::mem_pestat] mean and std.dev: (318.55, 155.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1121)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (305, 452, 754)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1652)
[M::mem_pestat] mean and std.dev: (452.90, 240.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2101)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 323, 804)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2020)
[M::mem_pestat] mean and std.dev: (432.88, 361.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2628)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 687326 sequences (100000244 bp) in 2.458 CPU sec, 2.459 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 279386, 18, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 215, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (250.56, 144.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 959)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 300, 428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 896)
[M::mem_pestat] mean and std.dev: (320.85, 155.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1130)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 606, 755)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1999)
[M::mem_pestat] mean and std.dev: (541.24, 339.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2621)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 487, 1618)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4404)
[M::mem_pestat] mean and std.dev: (906.13, 1029.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5797)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 279244, 8, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 273, 399)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709)
[M::mem_pestat] mean and std.dev: (278.25, 96.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 300, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 902)
[M::mem_pestat] mean and std.dev: (321.24, 156.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1138)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 396, 909)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2317)
[M::mem_pestat] mean and std.dev: (471.80, 329.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3021)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 686594 reads in 335.303 CPU sec, 10.711 real sec
sorting block 105, #reads = 1064720 mem = 536880917 peak = 1091665920
[M::mem_process_seqs] Processed 686064 reads in 242.681 CPU sec, 7.784 real sec
[M::mem_process_seqs] Processed 686032 reads in 271.993 CPU sec, 8.725 real sec
sorting block 106, #reads = 1063001 mem = 536882036 peak = 1091665920
[M::process] read 685342 sequences (100000080 bp) in 2.998 CPU sec, 3.147 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 280345, 10, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 229, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (216.88, 117.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 973)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 292, 421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 885)
[M::mem_pestat] mean and std.dev: (315.26, 155.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1117)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (6, 707, 1609)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4815)
[M::mem_pestat] mean and std.dev: (784.30, 866.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6418)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 281, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 992)
[M::mem_pestat] mean and std.dev: (306.26, 156.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1262)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 684808 sequences (100000236 bp) in 2.647 CPU sec, 2.717 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 279613, 7, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 411, 881)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2177)
[M::mem_pestat] mean and std.dev: (469.23, 331.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2825)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 303, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 904)
[M::mem_pestat] mean and std.dev: (323.97, 157.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1140)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 280, 1042)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2630)
[M::mem_pestat] mean and std.dev: (480.78, 397.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3424)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 687326 reads in 219.198 CPU sec, 6.938 real sec
[M::process] read 686088 sequences (100000200 bp) in 2.439 CPU sec, 2.458 real sec...
sorting block 107, #reads = 1063313 mem = 536878644 peak = 1091665920
[M::mem_process_seqs] Processed 685342 reads in 149.490 CPU sec, 4.899 real sec
sorting block 108, #reads = 1064149 mem = 536878721 peak = 1091665920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 279687, 19, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 277, 479)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1129)
[M::mem_pestat] mean and std.dev: (291.90, 173.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1454)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 307, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 921)
[M::mem_pestat] mean and std.dev: (328.93, 161.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1162)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 440, 1174)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3132)
[M::mem_pestat] mean and std.dev: (833.37, 887.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4385)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (140, 212, 424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 992)
[M::mem_pestat] mean and std.dev: (310.17, 237.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1276)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 684288 sequences (100000117 bp) in 2.948 CPU sec, 3.099 real sec...
[M::process] read 683830 sequences (100000198 bp) in 2.420 CPU sec, 2.426 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 280082, 19, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 242, 676)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1722)
[M::mem_pestat] mean and std.dev: (338.38, 247.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2245)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 297, 428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 898)
[M::mem_pestat] mean and std.dev: (321.09, 159.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1133)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (127, 484, 2727)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7927)
[M::mem_pestat] mean and std.dev: (1762.00, 2163.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10527)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 272, 380)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 794)
[M::mem_pestat] mean and std.dev: (273.13, 142.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1001)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684808 reads in 217.642 CPU sec, 7.087 real sec
[M::mem_process_seqs] Processed 686088 reads in 145.144 CPU sec, 4.600 real sec
sorting block 109, #reads = 1064568 mem = 536877273 peak = 1091665920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 279202, 16, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 321, 505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1095)
[M::mem_pestat] mean and std.dev: (340.47, 207.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1390)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 311, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 938)
[M::mem_pestat] mean and std.dev: (333.47, 163.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1184)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (58, 410, 825)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2359)
[M::mem_pestat] mean and std.dev: (457.81, 468.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3126)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (283, 412, 687)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1495)
[M::mem_pestat] mean and std.dev: (457.78, 285.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1899)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683566 sequences (100000105 bp) in 3.234 CPU sec, 3.406 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 278783, 11, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 339, 541)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1177)
[M::mem_pestat] mean and std.dev: (315.95, 138.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1495)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 314, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 952)
[M::mem_pestat] mean and std.dev: (337.37, 166.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1202)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (291, 916, 1382)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3564)
[M::mem_pestat] mean and std.dev: (832.55, 560.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4655)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 269, 422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 886)
[M::mem_pestat] mean and std.dev: (288.65, 162.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1118)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683670 sequences (100000116 bp) in 2.380 CPU sec, 2.383 real sec...
[M::mem_process_seqs] Processed 684288 reads in 212.218 CPU sec, 6.821 real sec
[M::mem_process_seqs] Processed 683830 reads in 143.609 CPU sec, 4.561 real sec
sorting block 110, #reads = 1065303 mem = 536878803 peak = 1091665920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 278814, 8, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 310, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 712)
[M::mem_pestat] mean and std.dev: (269.45, 109.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 883)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 315, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 953)
[M::mem_pestat] mean and std.dev: (338.55, 167.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1203)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 341, 554)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1156)
[M::mem_pestat] mean and std.dev: (402.67, 214.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1457)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683720 sequences (100000071 bp) in 2.844 CPU sec, 2.920 real sec...
[M::process] read 682916 sequences (100000131 bp) in 2.420 CPU sec, 2.416 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 278735, 12, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 351, 978)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2530)
[M::mem_pestat] mean and std.dev: (487.68, 377.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3306)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 318, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 968)
[M::mem_pestat] mean and std.dev: (341.54, 169.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1223)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (295, 721, 1158)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2884)
[M::mem_pestat] mean and std.dev: (623.18, 413.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3747)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 308, 632)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1512)
[M::mem_pestat] mean and std.dev: (323.04, 235.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1952)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683566 reads in 213.303 CPU sec, 6.767 real sec
sorting block 111, #reads = 1064513 mem = 536878631 peak = 1091665920
[M::mem_process_seqs] Processed 683670 reads in 142.425 CPU sec, 4.516 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 278823, 14, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (131, 251, 610)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1568)
[M::mem_pestat] mean and std.dev: (294.30, 216.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2047)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 316, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 956)
[M::mem_pestat] mean and std.dev: (339.50, 168.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1207)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (654, 1003, 1505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3207)
[M::mem_pestat] mean and std.dev: (1071.31, 864.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4527)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 287, 484)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1086)
[M::mem_pestat] mean and std.dev: (299.93, 159.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1387)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682896 sequences (100000131 bp) in 2.930 CPU sec, 2.996 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 278141, 15, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 234, 536)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1254)
[M::mem_pestat] mean and std.dev: (341.00, 266.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1613)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 320, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 961)
[M::mem_pestat] mean and std.dev: (342.08, 168.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1213)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (627, 701, 1391)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2919)
[M::mem_pestat] mean and std.dev: (818.07, 426.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3683)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (265, 383, 491)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 943)
[M::mem_pestat] mean and std.dev: (389.93, 190.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1169)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682770 sequences (100000096 bp) in 2.490 CPU sec, 2.490 real sec...
[M::mem_process_seqs] Processed 683720 reads in 209.543 CPU sec, 6.671 real sec
sorting block 112, #reads = 1062602 mem = 536879862 peak = 1091665920
[M::mem_process_seqs] Processed 682916 reads in 141.681 CPU sec, 4.483 real sec
sorting block 113, #reads = 1064073 mem = 536880694 peak = 1099862016
[M::process] read 684424 sequences (100000251 bp) in 2.865 CPU sec, 2.927 real sec...
[M::process] read 689588 sequences (100000052 bp) in 2.460 CPU sec, 2.459 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 278738, 14, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 404, 525)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1205)
[M::mem_pestat] mean and std.dev: (363.34, 226.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1545)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 324, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 975)
[M::mem_pestat] mean and std.dev: (346.07, 170.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1231)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 1052, 3454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9910)
[M::mem_pestat] mean and std.dev: (1644.79, 1630.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13138)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 400, 531)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1095)
[M::mem_pestat] mean and std.dev: (380.34, 234.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1377)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682770 reads in 117.667 CPU sec, 3.746 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 278056, 15, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 306, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1036)
[M::mem_pestat] mean and std.dev: (302.77, 156.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1323)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 321, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 971)
[M::mem_pestat] mean and std.dev: (344.20, 170.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1226)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (278, 515, 721)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1607)
[M::mem_pestat] mean and std.dev: (484.47, 355.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2050)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 350, 480)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 966)
[M::mem_pestat] mean and std.dev: (330.46, 168.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1209)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 688444 sequences (100000189 bp) in 2.640 CPU sec, 2.641 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 278473, 21, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 359, 1457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3967)
[M::mem_pestat] mean and std.dev: (674.42, 751.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5222)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 310, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 949)
[M::mem_pestat] mean and std.dev: (334.94, 167.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1199)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (249, 612, 701)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1605)
[M::mem_pestat] mean and std.dev: (509.16, 317.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2057)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 283, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 855)
[M::mem_pestat] mean and std.dev: (275.21, 97.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1064)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682896 reads in 348.876 CPU sec, 11.158 real sec
sorting block 114, #reads = 1062494 mem = 536882791 peak = 1099862016
[M::mem_process_seqs] Processed 684424 reads in 195.863 CPU sec, 6.291 real sec
sorting block 115, #reads = 1056797 mem = 536878180 peak = 1099862016
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 281135, 10, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 230, 416)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 878)
[M::mem_pestat] mean and std.dev: (284.19, 163.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1109)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 282, 412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 868)
[M::mem_pestat] mean and std.dev: (308.68, 155.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1096)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (447, 723, 3290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8976)
[M::mem_pestat] mean and std.dev: (1840.80, 1750.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11819)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (260, 344, 509)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1007)
[M::mem_pestat] mean and std.dev: (376.19, 179.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1256)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 687162 sequences (100000097 bp) in 3.026 CPU sec, 3.151 real sec...
[M::process] read 687012 sequences (100000033 bp) in 2.370 CPU sec, 2.373 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 280894, 10, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 304, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 920)
[M::mem_pestat] mean and std.dev: (304.00, 166.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1164)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 288, 418)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 880)
[M::mem_pestat] mean and std.dev: (313.61, 157.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1111)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (640, 780, 2252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5476)
[M::mem_pestat] mean and std.dev: (1285.30, 798.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7088)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 306, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 992)
[M::mem_pestat] mean and std.dev: (329.13, 183.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1253)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 689588 reads in 215.055 CPU sec, 6.811 real sec
[M::mem_process_seqs] Processed 688444 reads in 145.315 CPU sec, 4.613 real sec
sorting block 116, #reads = 1063062 mem = 536878914 peak = 1099862016
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 280014, 8, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 411, 1381)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3705)
[M::mem_pestat] mean and std.dev: (436.27, 358.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4867)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 294, 422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 884)
[M::mem_pestat] mean and std.dev: (317.61, 157.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1115)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 306, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 913)
[M::mem_pestat] mean and std.dev: (321.70, 127.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1134)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 686312 sequences (100000081 bp) in 2.915 CPU sec, 3.022 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 280549, 16, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 297, 621)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1513)
[M::mem_pestat] mean and std.dev: (417.50, 335.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1959)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 295, 423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 887)
[M::mem_pestat] mean and std.dev: (318.14, 157.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1119)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 165, 2103)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6007)
[M::mem_pestat] mean and std.dev: (876.12, 943.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7959)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 451, 1120)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2882)
[M::mem_pestat] mean and std.dev: (640.11, 635.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3763)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 685754 sequences (100000196 bp) in 2.370 CPU sec, 2.374 real sec...
[M::mem_process_seqs] Processed 687162 reads in 198.938 CPU sec, 6.287 real sec
sorting block 117, #reads = 1068322 mem = 536878821 peak = 1099862016
[M::mem_process_seqs] Processed 687012 reads in 141.347 CPU sec, 4.491 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 279752, 16, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 339, 384)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (270.26, 89.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 855)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 300, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 908)
[M::mem_pestat] mean and std.dev: (323.48, 160.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1146)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 215, 636)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1584)
[M::mem_pestat] mean and std.dev: (376.75, 300.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2058)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 361, 557)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1207)
[M::mem_pestat] mean and std.dev: (354.00, 175.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1532)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 685592 sequences (100000262 bp) in 2.828 CPU sec, 2.908 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 279725, 11, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (252, 325, 694)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1578)
[M::mem_pestat] mean and std.dev: (351.65, 201.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2020)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 304, 434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 910)
[M::mem_pestat] mean and std.dev: (325.61, 160.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1148)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (541, 675, 817)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1369)
[M::mem_pestat] mean and std.dev: (627.10, 194.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1645)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 311, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 959)
[M::mem_pestat] mean and std.dev: (273.40, 104.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1211)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 685334 sequences (100000156 bp) in 2.410 CPU sec, 2.409 real sec...
[M::mem_process_seqs] Processed 686312 reads in 193.894 CPU sec, 6.130 real sec
sorting block 118, #reads = 1068639 mem = 536881611 peak = 1099862016
[M::mem_process_seqs] Processed 685754 reads in 130.784 CPU sec, 4.389 real sec
sorting block 119, #reads = 1068902 mem = 536878676 peak = 1099862016
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 279365, 5, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 256, 481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1137)
[M::mem_pestat] mean and std.dev: (313.54, 215.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1465)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 305, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 922)
[M::mem_pestat] mean and std.dev: (328.36, 162.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1164)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 221, 382)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (263.88, 108.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 685296 sequences (100000088 bp) in 2.886 CPU sec, 2.974 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 279678, 17, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 288, 867)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2319)
[M::mem_pestat] mean and std.dev: (456.74, 512.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3045)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 306, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 926)
[M::mem_pestat] mean and std.dev: (328.72, 163.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1169)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (460, 1100, 4422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12346)
[M::mem_pestat] mean and std.dev: (1834.24, 1887.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16308)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 326, 404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 806)
[M::mem_pestat] mean and std.dev: (285.21, 127.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1007)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 684778 sequences (100000242 bp) in 2.440 CPU sec, 2.435 real sec...
[M::mem_process_seqs] Processed 685592 reads in 197.281 CPU sec, 6.486 real sec
[M::mem_process_seqs] Processed 685334 reads in 130.977 CPU sec, 4.149 real sec
sorting block 120, #reads = 1068562 mem = 536879720 peak = 1099862016
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 279847, 14, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 432, 700)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1626)
[M::mem_pestat] mean and std.dev: (434.89, 336.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2089)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 308, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 926)
[M::mem_pestat] mean and std.dev: (330.26, 163.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1169)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (37, 311, 1454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4288)
[M::mem_pestat] mean and std.dev: (932.57, 1241.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5897)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (399, 566, 1579)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3939)
[M::mem_pestat] mean and std.dev: (766.16, 543.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5119)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 684740 sequences (100000183 bp) in 2.888 CPU sec, 2.980 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 279527, 6, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 522, 1164)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3094)
[M::mem_pestat] mean and std.dev: (608.81, 420.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4059)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 309, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 925)
[M::mem_pestat] mean and std.dev: (330.92, 162.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1167)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 347, 931)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2345)
[M::mem_pestat] mean and std.dev: (559.97, 553.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3052)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 685200 sequences (100000282 bp) in 2.430 CPU sec, 2.430 real sec...
[M::mem_process_seqs] Processed 685296 reads in 187.371 CPU sec, 5.929 real sec
[M::mem_process_seqs] Processed 684778 reads in 126.998 CPU sec, 4.023 real sec
sorting block 121, #reads = 1068526 mem = 536876305 peak = 1099862016
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 279502, 8, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 216, 1170)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3236)
[M::mem_pestat] mean and std.dev: (643.86, 814.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4269)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 308, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 922)
[M::mem_pestat] mean and std.dev: (330.13, 162.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1163)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 280, 484)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1010)
[M::mem_pestat] mean and std.dev: (327.07, 162.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1273)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 685188 sequences (100000027 bp) in 2.922 CPU sec, 2.999 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 279515, 9, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 255, 633)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1549)
[M::mem_pestat] mean and std.dev: (401.56, 301.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2007)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 306, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 911)
[M::mem_pestat] mean and std.dev: (327.11, 160.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1149)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 375, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 992)
[M::mem_pestat] mean and std.dev: (312.84, 144.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1264)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 684636 sequences (100000299 bp) in 2.420 CPU sec, 2.421 real sec...
[M::mem_process_seqs] Processed 684740 reads in 190.725 CPU sec, 6.026 real sec
sorting block 122, #reads = 1068888 mem = 536879000 peak = 1099862016
[M::mem_process_seqs] Processed 685200 reads in 130.698 CPU sec, 4.203 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 279900, 5, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 311, 404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 744)
[M::mem_pestat] mean and std.dev: (318.81, 130.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 914)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 308, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 924)
[M::mem_pestat] mean and std.dev: (329.45, 161.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1166)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 283, 426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 940)
[M::mem_pestat] mean and std.dev: (261.18, 140.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1197)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683868 sequences (100000121 bp) in 2.920 CPU sec, 2.977 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 279358, 13, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 287, 882)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2258)
[M::mem_pestat] mean and std.dev: (527.79, 470.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2946)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 312, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 930)
[M::mem_pestat] mean and std.dev: (333.13, 163.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1173)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (580, 1039, 1457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3211)
[M::mem_pestat] mean and std.dev: (974.08, 567.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4088)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 253, 473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1091)
[M::mem_pestat] mean and std.dev: (241.07, 113.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1400)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 684148 sequences (100000217 bp) in 2.400 CPU sec, 2.405 real sec...
[M::mem_process_seqs] Processed 685188 reads in 199.900 CPU sec, 6.392 real sec
sorting block 123, #reads = 1065857 mem = 536878271 peak = 1099862016
[M::mem_process_seqs] Processed 684636 reads in 140.016 CPU sec, 4.439 real sec
sorting block 124, #reads = 1066429 mem = 536881500 peak = 1127043072
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 279300, 11, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 310, 416)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 834)
[M::mem_pestat] mean and std.dev: (297.62, 136.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1043)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 313, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 925)
[M::mem_pestat] mean and std.dev: (332.98, 161.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1166)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (5, 165, 1149)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3437)
[M::mem_pestat] mean and std.dev: (605.64, 732.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4581)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 291, 531)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1113)
[M::mem_pestat] mean and std.dev: (323.15, 161.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1404)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683864 sequences (100000158 bp) in 2.834 CPU sec, 2.901 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 279739, 10, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 358, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 873)
[M::mem_pestat] mean and std.dev: (308.61, 125.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1083)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 683384 sequences (100000102 bp) in 2.410 CPU sec, 2.416 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (202, 314, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 940)
[M::mem_pestat] mean and std.dev: (335.57, 164.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1186)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 186, 1062)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2904)
[M::mem_pestat] mean and std.dev: (639.60, 694.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3825)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 251, 910)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2364)
[M::mem_pestat] mean and std.dev: (322.92, 267.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3091)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683868 reads in 196.282 CPU sec, 6.197 real sec
[M::mem_process_seqs] Processed 684148 reads in 135.165 CPU sec, 4.498 real sec
sorting block 125, #reads = 1066965 mem = 536878333 peak = 1127043072
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (17, 279013, 4, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 198, 427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 983)
[M::mem_pestat] mean and std.dev: (247.87, 170.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1261)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 314, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 940)
[M::mem_pestat] mean and std.dev: (335.58, 164.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1186)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 376, 518)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1060)
[M::mem_pestat] mean and std.dev: (384.18, 205.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1331)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683268 sequences (100000132 bp) in 3.375 CPU sec, 3.578 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 278935, 7, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 276, 523)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1229)
[M::mem_pestat] mean and std.dev: (329.88, 216.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1582)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 316, 451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 945)
[M::mem_pestat] mean and std.dev: (338.25, 166.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1192)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 300, 762)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1846)
[M::mem_pestat] mean and std.dev: (422.32, 369.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2388)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683732 sequences (100000181 bp) in 2.430 CPU sec, 2.430 real sec...
[M::mem_process_seqs] Processed 683864 reads in 207.666 CPU sec, 6.789 real sec
sorting block 126, #reads = 1066696 mem = 536878747 peak = 1127043072
[M::mem_process_seqs] Processed 683384 reads in 139.675 CPU sec, 4.531 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 278766, 27, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 255, 520)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1282)
[M::mem_pestat] mean and std.dev: (278.40, 190.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1663)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 318, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 948)
[M::mem_pestat] mean and std.dev: (339.02, 165.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1196)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (493, 677, 872)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1630)
[M::mem_pestat] mean and std.dev: (625.91, 327.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2009)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 310, 811)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2011)
[M::mem_pestat] mean and std.dev: (479.75, 420.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2611)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683234 sequences (100000010 bp) in 2.815 CPU sec, 2.892 real sec...
[M::process] read 683304 sequences (100000028 bp) in 2.440 CPU sec, 2.437 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 279227, 9, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 283, 480)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1042)
[M::mem_pestat] mean and std.dev: (363.69, 217.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1323)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 314, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 935)
[M::mem_pestat] mean and std.dev: (335.95, 164.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1179)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 423, 590)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1286)
[M::mem_pestat] mean and std.dev: (369.75, 178.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1634)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683268 reads in 201.060 CPU sec, 6.474 real sec
sorting block 127, #reads = 1066749 mem = 536880560 peak = 1127043072
[M::mem_process_seqs] Processed 683732 reads in 135.815 CPU sec, 4.313 real sec
sorting block 128, #reads = 1065727 mem = 536880390 peak = 1127043072
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 278422, 11, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 227, 378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 762)
[M::mem_pestat] mean and std.dev: (251.86, 120.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 316, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 954)
[M::mem_pestat] mean and std.dev: (339.38, 167.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1204)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (282, 622, 1169)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2943)
[M::mem_pestat] mean and std.dev: (730.10, 633.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3830)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 355, 763)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1833)
[M::mem_pestat] mean and std.dev: (412.30, 267.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2368)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683094 sequences (100000106 bp) in 2.884 CPU sec, 2.952 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 278416, 8, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 285, 1018)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2664)
[M::mem_pestat] mean and std.dev: (433.86, 429.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3487)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 314, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 933)
[M::mem_pestat] mean and std.dev: (335.52, 163.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1176)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 277, 512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1046)
[M::mem_pestat] mean and std.dev: (326.66, 151.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1313)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683380 sequences (100000026 bp) in 2.450 CPU sec, 2.442 real sec...
[M::mem_process_seqs] Processed 683234 reads in 201.810 CPU sec, 6.377 real sec
[M::mem_process_seqs] Processed 683304 reads in 140.297 CPU sec, 4.530 real sec
sorting block 129, #reads = 1063864 mem = 536880463 peak = 1127043072
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 278418, 7, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 250, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1053)
[M::mem_pestat] mean and std.dev: (271.73, 175.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1355)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 316, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 948)
[M::mem_pestat] mean and std.dev: (338.92, 167.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1196)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 350, 492)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1104)
[M::mem_pestat] mean and std.dev: (328.71, 180.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1410)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683320 sequences (100000010 bp) in 2.909 CPU sec, 2.988 real sec...
[M::process] read 683772 sequences (100000216 bp) in 2.410 CPU sec, 2.404 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 278651, 16, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 302, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 983)
[M::mem_pestat] mean and std.dev: (322.64, 173.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1255)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 315, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 942)
[M::mem_pestat] mean and std.dev: (338.10, 166.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1188)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (76, 460, 1424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4120)
[M::mem_pestat] mean and std.dev: (684.12, 766.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5468)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 291, 417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 903)
[M::mem_pestat] mean and std.dev: (276.31, 131.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1146)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683094 reads in 202.295 CPU sec, 6.468 real sec
sorting block 130, #reads = 1063849 mem = 536881959 peak = 1127043072
[M::mem_process_seqs] Processed 683380 reads in 224.116 CPU sec, 7.267 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 278414, 12, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 295, 1433)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3881)
[M::mem_pestat] mean and std.dev: (740.28, 763.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5105)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 312, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 943)
[M::mem_pestat] mean and std.dev: (336.86, 167.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1190)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (371, 437, 697)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1349)
[M::mem_pestat] mean and std.dev: (485.36, 204.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1675)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 317, 434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 788)
[M::mem_pestat] mean and std.dev: (319.15, 123.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 965)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683244 sequences (100000266 bp) in 3.038 CPU sec, 3.097 real sec...
[M::process] read 683040 sequences (100000130 bp) in 2.473 CPU sec, 2.482 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 278848, 15, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 350, 559)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1229)
[M::mem_pestat] mean and std.dev: (320.79, 139.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1564)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 314, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 944)
[M::mem_pestat] mean and std.dev: (337.23, 166.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1191)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (481, 3084, 6572)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 18754)
[M::mem_pestat] mean and std.dev: (3274.47, 2653.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 24845)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 386, 485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1013)
[M::mem_pestat] mean and std.dev: (319.46, 171.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1277)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683772 reads in 206.379 CPU sec, 6.686 real sec
sorting block 131, #reads = 1064449 mem = 536878931 peak = 1127043072
[M::mem_process_seqs] Processed 683320 reads in 228.375 CPU sec, 7.528 real sec
sorting block 132, #reads = 1064148 mem = 536879110 peak = 1127043072
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 278558, 9, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 253, 850)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2228)
[M::mem_pestat] mean and std.dev: (575.20, 637.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3126)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 315, 451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 947)
[M::mem_pestat] mean and std.dev: (338.45, 167.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1195)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 374, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 957)
[M::mem_pestat] mean and std.dev: (331.92, 186.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1208)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683046 sequences (100000273 bp) in 2.897 CPU sec, 2.986 real sec...
[M::process] read 694556 sequences (100000122 bp) in 2.570 CPU sec, 2.573 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 278470, 18, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 269, 578)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1436)
[M::mem_pestat] mean and std.dev: (344.68, 260.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1865)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 318, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 952)
[M::mem_pestat] mean and std.dev: (340.88, 168.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1201)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (432, 681, 1903)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4845)
[M::mem_pestat] mean and std.dev: (1057.39, 749.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6316)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 256, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 994)
[M::mem_pestat] mean and std.dev: (296.56, 169.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1267)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683244 reads in 220.252 CPU sec, 7.091 real sec
[M::mem_process_seqs] Processed 683040 reads in 149.646 CPU sec, 4.744 real sec
sorting block 133, #reads = 1062119 mem = 536881464 peak = 1127043072
[M::process] read 692566 sequences (100000189 bp) in 3.035 CPU sec, 3.091 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 282218, 7, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 255, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 996)
[M::mem_pestat] mean and std.dev: (314.67, 208.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1269)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 257, 377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 789)
[M::mem_pestat] mean and std.dev: (285.03, 144.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 995)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 325, 923)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2319)
[M::mem_pestat] mean and std.dev: (476.65, 382.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3017)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 690848 sequences (100000223 bp) in 2.490 CPU sec, 2.493 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 277949, 16, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 347, 843)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2103)
[M::mem_pestat] mean and std.dev: (512.09, 419.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2733)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 319, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 964)
[M::mem_pestat] mean and std.dev: (343.08, 171.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1217)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (416, 1045, 1890)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4838)
[M::mem_pestat] mean and std.dev: (1088.13, 1000.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6312)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 232, 632)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1522)
[M::mem_pestat] mean and std.dev: (261.89, 153.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1967)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694556 reads in 236.278 CPU sec, 7.477 real sec
[M::mem_process_seqs] Processed 683046 reads in 269.256 CPU sec, 8.613 real sec
sorting block 134, #reads = 1060431 mem = 536878066 peak = 1127043072
[M::process] read 689572 sequences (100000228 bp) in 3.017 CPU sec, 3.094 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 281565, 12, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (290, 325, 1128)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2804)
[M::mem_pestat] mean and std.dev: (585.16, 535.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3642)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 274, 397)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 833)
[M::mem_pestat] mean and std.dev: (298.67, 148.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1051)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (627, 1469, 2035)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4851)
[M::mem_pestat] mean and std.dev: (1164.09, 697.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6259)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (271, 390, 858)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2032)
[M::mem_pestat] mean and std.dev: (516.69, 351.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2619)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 688800 sequences (100000217 bp) in 2.540 CPU sec, 2.533 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 282267, 7, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 337, 788)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1922)
[M::mem_pestat] mean and std.dev: (485.94, 385.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2489)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 266, 389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 817)
[M::mem_pestat] mean and std.dev: (292.38, 146.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1031)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 314, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 818)
[M::mem_pestat] mean and std.dev: (311.83, 145.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1011)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 690848 reads in 224.636 CPU sec, 7.097 real sec
sorting block 135, #reads = 1054445 mem = 536885051 peak = 1127043072
[M::mem_process_seqs] Processed 692566 reads in 259.498 CPU sec, 8.299 real sec
[M::process] read 688300 sequences (100000044 bp) in 3.040 CPU sec, 3.103 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 280883, 6, 18)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 423, 1294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3564)
[M::mem_pestat] mean and std.dev: (668.76, 804.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4699)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 281, 404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 846)
[M::mem_pestat] mean and std.dev: (303.65, 148.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1067)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 206, 397)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 873)
[M::mem_pestat] mean and std.dev: (280.31, 221.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1167)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 688314 sequences (100000202 bp) in 1.818 CPU sec, 1.823 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 281125, 11, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 280, 497)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1151)
[M::mem_pestat] mean and std.dev: (362.64, 260.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1478)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 286, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 855)
[M::mem_pestat] mean and std.dev: (307.53, 149.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1078)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 1136, 1919)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5255)
[M::mem_pestat] mean and std.dev: (1195.45, 1069.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6923)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 281, 556)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1246)
[M::mem_pestat] mean and std.dev: (344.19, 181.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1591)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 689572 reads in 195.566 CPU sec, 6.202 real sec
sorting block 136, #reads = 1061943 mem = 536879397 peak = 1127043072
[M::mem_process_seqs] Processed 688800 reads in 225.300 CPU sec, 7.179 real sec
sorting block 137, #reads = 1062675 mem = 536882305 peak = 1127043072
[M::process] read 687372 sequences (100000049 bp) in 2.501 CPU sec, 2.547 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 280167, 11, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 263, 429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 917)
[M::mem_pestat] mean and std.dev: (285.38, 159.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1161)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 287, 415)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 871)
[M::mem_pestat] mean and std.dev: (310.41, 152.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1099)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (470, 574, 735)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1265)
[M::mem_pestat] mean and std.dev: (561.20, 216.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1530)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (389, 635, 1175)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2747)
[M::mem_pestat] mean and std.dev: (619.96, 380.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3533)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 686540 sequences (100000286 bp) in 2.180 CPU sec, 2.177 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 280253, 12, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 350, 647)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1593)
[M::mem_pestat] mean and std.dev: (465.76, 388.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2066)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 288, 417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 877)
[M::mem_pestat] mean and std.dev: (312.50, 155.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1107)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1637, 2768, 3569)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7433)
[M::mem_pestat] mean and std.dev: (2621.42, 1789.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9781)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (258, 343, 481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 927)
[M::mem_pestat] mean and std.dev: (379.05, 189.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1150)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 688300 reads in 204.735 CPU sec, 6.494 real sec
[M::mem_process_seqs] Processed 688314 reads in 141.452 CPU sec, 4.502 real sec
sorting block 138, #reads = 1060030 mem = 536880321 peak = 1127043072
[M::process] read 686046 sequences (100000179 bp) in 2.583 CPU sec, 2.651 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 280435, 5, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 239, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 532)
[M::mem_pestat] mean and std.dev: (221.07, 70.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 647)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 293, 424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 892)
[M::mem_pestat] mean and std.dev: (316.82, 156.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1126)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 368, 572)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1218)
[M::mem_pestat] mean and std.dev: (400.36, 206.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1541)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 686594 sequences (100000133 bp) in 2.427 CPU sec, 2.431 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 280011, 16, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 350, 589)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1385)
[M::mem_pestat] mean and std.dev: (303.86, 158.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1783)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 298, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 904)
[M::mem_pestat] mean and std.dev: (320.95, 157.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1141)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 388, 819)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2169)
[M::mem_pestat] mean and std.dev: (451.33, 462.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2844)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 389, 653)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1481)
[M::mem_pestat] mean and std.dev: (486.44, 315.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1895)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 279714, 21, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 524, 822)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2200)
[M::mem_pestat] mean and std.dev: (475.48, 424.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2889)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 298, 428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 898)
[M::mem_pestat] mean and std.dev: (320.70, 157.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1133)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (552, 874, 4523)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12465)
[M::mem_pestat] mean and std.dev: (1635.71, 1638.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16436)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 286, 414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 806)
[M::mem_pestat] mean and std.dev: (302.76, 146.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1002)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 687372 reads in 290.261 CPU sec, 9.375 real sec
sorting block 139, #reads = 1062909 mem = 536885423 peak = 1127043072
[M::mem_process_seqs] Processed 686540 reads in 218.194 CPU sec, 6.974 real sec
[M::mem_process_seqs] Processed 686046 reads in 244.361 CPU sec, 7.815 real sec
sorting block 140, #reads = 1063624 mem = 536877413 peak = 1127043072
[M::process] read 685578 sequences (100000111 bp) in 2.591 CPU sec, 2.732 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 279710, 4, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 301, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 955)
[M::mem_pestat] mean and std.dev: (309.53, 151.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1205)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 294, 422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 882)
[M::mem_pestat] mean and std.dev: (316.05, 153.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1112)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 434, 704)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1714)
[M::mem_pestat] mean and std.dev: (441.92, 243.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2219)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 684170 sequences (100000204 bp) in 2.435 CPU sec, 2.499 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 278677, 7, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 335, 640)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1564)
[M::mem_pestat] mean and std.dev: (339.19, 234.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2026)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 299, 428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 894)
[M::mem_pestat] mean and std.dev: (320.58, 155.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1127)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 357, 889)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2223)
[M::mem_pestat] mean and std.dev: (462.85, 423.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2890)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 686594 reads in 208.904 CPU sec, 6.618 real sec
[M::process] read 684520 sequences (100000206 bp) in 2.362 CPU sec, 2.372 real sec...
sorting block 141, #reads = 1060423 mem = 536878711 peak = 1127043072
[M::process] read 685056 sequences (100000155 bp) in 2.153 CPU sec, 2.161 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 278833, 7, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 278, 1293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3497)
[M::mem_pestat] mean and std.dev: (588.69, 679.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4599)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 311, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 921)
[M::mem_pestat] mean and std.dev: (330.93, 159.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1161)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 313, 384)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 768)
[M::mem_pestat] mean and std.dev: (287.69, 130.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 960)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684170 reads in 113.032 CPU sec, 3.855 real sec
[M::mem_process_seqs] Processed 685578 reads in 285.239 CPU sec, 9.304 real sec
sorting block 142, #reads = 1060757 mem = 536883248 peak = 1127043072
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 279044, 19, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 300, 593)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1383)
[M::mem_pestat] mean and std.dev: (394.00, 278.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1778)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 308, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 911)
[M::mem_pestat] mean and std.dev: (328.13, 158.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1148)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 605, 1153)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3071)
[M::mem_pestat] mean and std.dev: (855.89, 822.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4146)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 259, 508)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1118)
[M::mem_pestat] mean and std.dev: (286.03, 122.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1423)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 684578 sequences (100000204 bp) in 2.850 CPU sec, 3.078 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 278851, 17, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 227, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1064)
[M::mem_pestat] mean and std.dev: (304.18, 223.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1361)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 302, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 899)
[M::mem_pestat] mean and std.dev: (323.49, 156.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1133)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 307, 1079)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2775)
[M::mem_pestat] mean and std.dev: (816.65, 875.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4319)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 273, 546)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1224)
[M::mem_pestat] mean and std.dev: (313.02, 173.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1563)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 684274 sequences (100000133 bp) in 2.310 CPU sec, 2.310 real sec...
[M::mem_process_seqs] Processed 684520 reads in 233.163 CPU sec, 7.427 real sec
sorting block 143, #reads = 1061823 mem = 536879976 peak = 1127043072
[M::mem_process_seqs] Processed 685056 reads in 143.363 CPU sec, 4.527 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 278872, 9, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 272, 563)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1235)
[M::mem_pestat] mean and std.dev: (328.74, 213.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1571)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 306, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 910)
[M::mem_pestat] mean and std.dev: (327.74, 159.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1147)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 372, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 911)
[M::mem_pestat] mean and std.dev: (333.21, 149.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1138)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 684048 sequences (100000056 bp) in 2.888 CPU sec, 2.982 real sec...
[M::process] read 684258 sequences (100000018 bp) in 2.280 CPU sec, 2.280 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 278556, 22, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 247, 494)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1184)
[M::mem_pestat] mean and std.dev: (321.97, 200.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1529)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 305, 434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 906)
[M::mem_pestat] mean and std.dev: (325.68, 157.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1142)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (765, 827, 1080)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (135, 1710)
[M::mem_pestat] mean and std.dev: (746.62, 203.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2025)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 245, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1004)
[M::mem_pestat] mean and std.dev: (287.56, 193.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1284)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684274 reads in 198.528 CPU sec, 6.266 real sec
sorting block 144, #reads = 1062397 mem = 536877232 peak = 1127043072
[M::mem_process_seqs] Processed 684578 reads in 227.276 CPU sec, 7.202 real sec
sorting block 145, #reads = 1062388 mem = 536880816 peak = 1127043072
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 278461, 9, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 350, 804)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2064)
[M::mem_pestat] mean and std.dev: (376.35, 315.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2694)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 307, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 914)
[M::mem_pestat] mean and std.dev: (329.23, 160.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1152)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 342, 567)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1265)
[M::mem_pestat] mean and std.dev: (347.65, 177.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1614)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683928 sequences (100000182 bp) in 2.950 CPU sec, 3.072 real sec...
[M::process] read 683770 sequences (100000262 bp) in 1.870 CPU sec, 1.873 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 278762, 17, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 316, 388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 742)
[M::mem_pestat] mean and std.dev: (296.63, 123.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 919)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 309, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 918)
[M::mem_pestat] mean and std.dev: (330.17, 160.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1157)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 1727, 5063)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 14743)
[M::mem_pestat] mean and std.dev: (2510.06, 2371.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 19583)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (336, 504, 2530)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6918)
[M::mem_pestat] mean and std.dev: (1254.56, 1519.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9112)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684258 reads in 193.475 CPU sec, 6.128 real sec
[M::mem_process_seqs] Processed 684048 reads in 217.277 CPU sec, 7.036 real sec
sorting block 146, #reads = 1064675 mem = 536880555 peak = 1127043072
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 278489, 15, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 397, 1041)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2733)
[M::mem_pestat] mean and std.dev: (672.63, 671.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3579)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 310, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 924)
[M::mem_pestat] mean and std.dev: (331.73, 161.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1165)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 450, 1247)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3279)
[M::mem_pestat] mean and std.dev: (551.93, 559.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4295)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 387, 639)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1535)
[M::mem_pestat] mean and std.dev: (404.89, 251.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1983)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683724 sequences (100000112 bp) in 2.822 CPU sec, 3.013 real sec...
[M::process] read 683952 sequences (100000291 bp) in 1.910 CPU sec, 1.914 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 278543, 21, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 207, 279)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 547)
[M::mem_pestat] mean and std.dev: (208.64, 100.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 681)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 310, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 933)
[M::mem_pestat] mean and std.dev: (333.38, 163.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1177)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (534, 649, 1902)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4638)
[M::mem_pestat] mean and std.dev: (1331.86, 1187.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6084)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 282, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 958)
[M::mem_pestat] mean and std.dev: (283.12, 131.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1215)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683928 reads in 189.149 CPU sec, 6.128 real sec
[M::mem_process_seqs] Processed 683770 reads in 124.989 CPU sec, 4.050 real sec
sorting block 147, #reads = 1064071 mem = 536879233 peak = 1127043072
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 278136, 10, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 359, 797)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1937)
[M::mem_pestat] mean and std.dev: (483.51, 395.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2507)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 311, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 936)
[M::mem_pestat] mean and std.dev: (333.88, 163.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1181)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 933, 1291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3449)
[M::mem_pestat] mean and std.dev: (805.00, 533.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4528)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 335, 647)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1577)
[M::mem_pestat] mean and std.dev: (396.24, 287.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2042)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683346 sequences (100000054 bp) in 2.496 CPU sec, 2.610 real sec...
[M::process] read 681916 sequences (100000137 bp) in 1.860 CPU sec, 1.859 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (17, 278117, 16, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (285, 413, 1257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3201)
[M::mem_pestat] mean and std.dev: (733.35, 688.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4173)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 311, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 939)
[M::mem_pestat] mean and std.dev: (334.50, 164.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1185)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (488, 754, 1065)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2219)
[M::mem_pestat] mean and std.dev: (758.47, 501.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2796)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 376, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 988)
[M::mem_pestat] mean and std.dev: (343.14, 175.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1253)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683724 reads in 188.090 CPU sec, 6.069 real sec
sorting block 148, #reads = 1064036 mem = 536881736 peak = 1127043072
[M::mem_process_seqs] Processed 683952 reads in 123.867 CPU sec, 4.052 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 278727, 11, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 349, 1274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3512)
[M::mem_pestat] mean and std.dev: (569.56, 556.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4631)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 315, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 950)
[M::mem_pestat] mean and std.dev: (338.32, 167.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1199)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (760, 2532, 2682)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6526)
[M::mem_pestat] mean and std.dev: (1709.27, 1064.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8448)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 264, 390)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 836)
[M::mem_pestat] mean and std.dev: (272.22, 130.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1059)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682878 sequences (100000151 bp) in 2.498 CPU sec, 2.608 real sec...
[M::process] read 493674 sequences (72250168 bp) in 1.470 CPU sec, 1.463 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 278732, 13, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 275, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 633)
[M::mem_pestat] mean and std.dev: (258.18, 97.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 786)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 327, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 973)
[M::mem_pestat] mean and std.dev: (348.73, 170.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1227)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (861, 874, 1707)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3399)
[M::mem_pestat] mean and std.dev: (1071.08, 600.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4245)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 404, 512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1090)
[M::mem_pestat] mean and std.dev: (349.21, 192.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1379)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683346 reads in 189.016 CPU sec, 6.120 real sec
sorting block 149, #reads = 1063705 mem = 536877500 peak = 1127043072
[M::mem_process_seqs] Processed 681916 reads in 122.586 CPU sec, 4.028 real sec
sorting block 150, #reads = 1063532 mem = 536879280 peak = 1127043072
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 278757, 7, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (128, 174, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1103)
[M::mem_pestat] mean and std.dev: (250.73, 200.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1428)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 317, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 947)
[M::mem_pestat] mean and std.dev: (340.33, 167.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1194)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 195, 390)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 880)
[M::mem_pestat] mean and std.dev: (242.88, 148.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1125)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 201273, 15, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 238, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 501)
[M::mem_pestat] mean and std.dev: (249.94, 100.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 654)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 315, 451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 947)
[M::mem_pestat] mean and std.dev: (337.65, 166.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1195)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (583, 690, 3559)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9511)
[M::mem_pestat] mean and std.dev: (1425.33, 1337.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12487)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 406, 938)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2420)
[M::mem_pestat] mean and std.dev: (598.39, 466.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3161)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682878 reads in 153.770 CPU sec, 5.091 real sec
[M::mem_process_seqs] Processed 493674 reads in 92.271 CPU sec, 2.983 real sec
sorting block 151, #reads = 1064418 mem = 536880560 peak = 1127043072
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000c06f2
  features: 1f8bfbff fffab20b
  extended: f1bf07ab 1a407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) Platinum 8559C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 161293228
overall: 70125809664 mem 28377.838 user 534.829 sys 949.098 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1136_253-T1-TDNA-1_A23MHWWLT4_1.L007\tPU:L007\tSM:1136_253-T1-TDNA-1_A23MHWWLT4_1\tLB:1136_253-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1136_253-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1136_253-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 949.125 sec; CPU: 28912.669 sec
sorting block 152, #reads = 376243 mem = 191060781 peak = 1127043072
uniq header count 1
merging 153 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000c06f2
  features: 1f8bfbff fffab20b
  extended: f1bf07ab 1a407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) Platinum 8559C
threads: 31 max 192
algo: util-sort
license: sentieon:util=1
output file size: 9678788766
output reads: 162541650
bam_mem_sort: 153 calls 95.250 user 1.803 sys 97.740 real
bam_write: 153 calls 53.788 user 3.267 sys 74.561 real
execute: 1 calls 37.078 user 1.821 sys 1017.580 real
merge_files: 1 calls 37.044 user 1.795 sys 68.255 real
parse_chunk: 2438 calls 142.969 user 33.483 sys 185.754 real
read_chunk: 6584 calls 75.224 user 45.449 sys 901.570 real
sort_block: 1 calls 50.385 user 44.691 sys 869.147 real
write_chunk: 4144 calls 36.605 user 1.350 sys 67.003 real
overall: 3555840000 mem 2703.374 user 109.472 sys 1017.598 real
ls: cannot access '*.cram': No such file or directory