Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/3d/9fe8485bba80ef951993098c216858/.command.sh
  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta.fai
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/d2/682b2838d274d64e0cfa6e4a122abd/1136_5L2-T1-TDNA-1_A23MHWWLT4_1/1136_5L2-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz
  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/BWAIndex
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/3d/9fe8485bba80ef951993098c216858/.command.run
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/d2/682b2838d274d64e0cfa6e4a122abd/1136_5L2-T1-TDNA-1_A23MHWWLT4_1/1136_5L2-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
==> STAGING COMPLETE (7 inputs)

cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1136_5L2-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 1978.934 CPU sec, 78.325 real sec
[M::process] read 682716 sequences (100000155 bp) in 0.993 CPU sec, 0.998 real sec...
[M::process] read 682048 sequences (100000264 bp) in 1.209 CPU sec, 1.213 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 284826, 0, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (263, 601, 2358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6548)
[M::mem_pestat] mean and std.dev: (1006.53, 1002.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8643)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 325, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 928)
[M::mem_pestat] mean and std.dev: (340.36, 161.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1167)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 283, 480)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1006)
[M::mem_pestat] mean and std.dev: (298.75, 113.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1269)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681222 sequences (100000032 bp) in 1.159 CPU sec, 1.160 real sec...
[M::process] read 680676 sequences (100000251 bp) in 1.159 CPU sec, 1.160 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (17, 284966, 7, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 229, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1055)
[M::mem_pestat] mean and std.dev: (285.47, 183.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1348)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 331, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 943)
[M::mem_pestat] mean and std.dev: (345.73, 163.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1186)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 283, 506)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1096)
[M::mem_pestat] mean and std.dev: (360.35, 207.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1391)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682716 reads in 152.860 CPU sec, 4.833 real sec
[M::mem_process_seqs] Processed 682048 reads in 93.553 CPU sec, 2.993 real sec
sorting block 0, #reads = 1080886 mem = 536878662 peak = 588374016
[M::process] read 680616 sequences (100000063 bp) in 1.660 CPU sec, 1.746 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (13, 284483, 4, 17)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 275, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 608)
[M::mem_pestat] mean and std.dev: (261.58, 88.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 737)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 337, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 957)
[M::mem_pestat] mean and std.dev: (351.58, 165.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1203)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 290, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1017)
[M::mem_pestat] mean and std.dev: (306.53, 140.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1297)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680196 sequences (100000191 bp) in 1.200 CPU sec, 1.196 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 284883, 1, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 285, 382)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 740)
[M::mem_pestat] mean and std.dev: (266.12, 113.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 919)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 340, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 961)
[M::mem_pestat] mean and std.dev: (353.67, 166.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1208)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (343, 372, 387)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (255, 475)
[M::mem_pestat] mean and std.dev: (362.36, 30.72)
[M::mem_pestat] low and high boundaries for proper pairs: (211, 519)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (15, 284091, 3, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 252, 1365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3801)
[M::mem_pestat] mean and std.dev: (665.53, 755.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5019)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 341, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 962)
[M::mem_pestat] mean and std.dev: (354.21, 166.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1209)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 380, 809)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1943)
[M::mem_pestat] mean and std.dev: (481.35, 335.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2510)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681222 reads in 206.890 CPU sec, 6.611 real sec
[M::mem_process_seqs] Processed 680676 reads in 152.993 CPU sec, 4.918 real sec
[M::mem_process_seqs] Processed 680616 reads in 167.146 CPU sec, 5.390 real sec
sorting block 1, #reads = 1081646 mem = 536878842 peak = 715374592
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (11, 284014, 5, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 211, 211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (211, 211)
[M::mem_pestat] mean and std.dev: (211.00, 0.00)
[M::mem_pestat] low and high boundaries for proper pairs: (211, 211)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
sorting block 2, #reads = 1082031 mem = 536877942 peak = 871936000
[M::mem_pestat] (25, 50, 75) percentile: (223, 343, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 961)
[M::mem_pestat] mean and std.dev: (355.63, 165.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1207)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (376, 383, 511)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (106, 781)
[M::mem_pestat] mean and std.dev: (383.17, 104.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 916)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680112 sequences (100000027 bp) in 2.298 CPU sec, 2.485 real sec...
[M::mem_process_seqs] Processed 680196 reads in 81.245 CPU sec, 2.652 real sec
[M::process] read 680036 sequences (100000113 bp) in 2.379 CPU sec, 2.514 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 284427, 0, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 453, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 993)
[M::mem_pestat] mean and std.dev: (355.90, 173.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1263)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 348, 476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 976)
[M::mem_pestat] mean and std.dev: (359.93, 167.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1226)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 328, 418)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 976)
[M::mem_pestat] mean and std.dev: (289.94, 151.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1255)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681388 sequences (100000244 bp) in 1.670 CPU sec, 1.676 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (17, 283894, 4, 19)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 245, 410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 890)
[M::mem_pestat] mean and std.dev: (256.71, 112.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1130)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 351, 478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 982)
[M::mem_pestat] mean and std.dev: (361.73, 168.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1234)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 870, 1286)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3474)
[M::mem_pestat] mean and std.dev: (697.63, 512.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4568)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680112 reads in 150.130 CPU sec, 4.721 real sec
[M::mem_process_seqs] Processed 680036 reads in 94.065 CPU sec, 2.955 real sec
sorting block 3, #reads = 1081531 mem = 536881804 peak = 871936000
[M::process] read 680890 sequences (100000280 bp) in 1.708 CPU sec, 1.772 real sec...
sorting block 4, #reads = 1081985 mem = 536878454 peak = 871936000
[M::process] read 680596 sequences (100000050 bp) in 1.932 CPU sec, 2.062 real sec...
[M::process] read 680832 sequences (100000262 bp) in 1.319 CPU sec, 1.329 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (9, 284103, 9, 8)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 340, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 967)
[M::mem_pestat] mean and std.dev: (354.43, 167.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1216)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_process_seqs] Processed 680890 reads in 85.386 CPU sec, 2.701 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 284249, 0, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 218, 814)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2092)
[M::mem_pestat] mean and std.dev: (422.81, 317.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2731)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 337, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 967)
[M::mem_pestat] mean and std.dev: (351.89, 166.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1217)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (106, 187, 296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 676)
[M::mem_pestat] mean and std.dev: (210.81, 105.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680732 sequences (100000096 bp) in 1.542 CPU sec, 1.545 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283588, 1, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 175, 415)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 917)
[M::mem_pestat] mean and std.dev: (289.00, 218.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1168)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 339, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 969)
[M::mem_pestat] mean and std.dev: (353.78, 166.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1219)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (270, 355, 544)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1092)
[M::mem_pestat] mean and std.dev: (375.24, 179.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1366)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681388 reads in 236.798 CPU sec, 7.545 real sec
sorting block 5, #reads = 1082853 mem = 536880163 peak = 871936000
[M::mem_process_seqs] Processed 680596 reads in 109.736 CPU sec, 3.511 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 283637, 4, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 265, 298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 552)
[M::mem_pestat] mean and std.dev: (253.00, 90.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 679)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 339, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 961)
[M::mem_pestat] mean and std.dev: (353.50, 166.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1208)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (258, 273, 617)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1335)
[M::mem_pestat] mean and std.dev: (391.05, 222.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1694)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680588 sequences (100000144 bp) in 2.289 CPU sec, 2.427 real sec...
[M::process] read 680580 sequences (100000263 bp) in 1.440 CPU sec, 1.445 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (18, 284020, 4, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 149, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (18, 318)
[M::mem_pestat] mean and std.dev: (165.24, 54.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 384)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 338, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 961)
[M::mem_pestat] mean and std.dev: (352.95, 165.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1208)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 546, 589)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1281)
[M::mem_pestat] mean and std.dev: (408.60, 173.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1627)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680832 reads in 156.007 CPU sec, 4.963 real sec
sorting block 6, #reads = 1081815 mem = 536879411 peak = 871936000
[M::mem_process_seqs] Processed 680732 reads in 96.340 CPU sec, 3.066 real sec
sorting block 7, #reads = 1082376 mem = 536883211 peak = 871936000
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (16, 283380, 7, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (111, 163, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 732)
[M::mem_pestat] mean and std.dev: (178.07, 89.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 939)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 335, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 945)
[M::mem_pestat] mean and std.dev: (349.77, 163.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1187)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 227, 308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 610)
[M::mem_pestat] mean and std.dev: (219.71, 81.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 761)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682736 sequences (100000281 bp) in 1.989 CPU sec, 2.123 real sec...
[M::process] read 680780 sequences (100000027 bp) in 1.370 CPU sec, 1.363 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (17, 284030, 2, 19)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 236, 273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 531)
[M::mem_pestat] mean and std.dev: (214.06, 75.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 660)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 332, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 936)
[M::mem_pestat] mean and std.dev: (347.72, 161.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1175)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 261, 1079)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2839)
[M::mem_pestat] mean and std.dev: (559.11, 551.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3719)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680588 reads in 157.241 CPU sec, 5.017 real sec
[M::mem_process_seqs] Processed 680580 reads in 97.513 CPU sec, 3.113 real sec
sorting block 8, #reads = 1081686 mem = 536883743 peak = 871936000
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 285105, 1, 15)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 170, 238)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 404)
[M::mem_pestat] mean and std.dev: (178.07, 65.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 487)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 318, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 896)
[M::mem_pestat] mean and std.dev: (332.64, 154.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1125)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 169, 247)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 427)
[M::mem_pestat] mean and std.dev: (202.20, 62.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 517)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681142 sequences (100000213 bp) in 2.640 CPU sec, 2.784 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 283400, 0, 16)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 194, 974)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2632)
[M::mem_pestat] mean and std.dev: (489.14, 538.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3461)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 329, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 925)
[M::mem_pestat] mean and std.dev: (344.51, 160.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1161)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 276, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 851)
[M::mem_pestat] mean and std.dev: (310.50, 144.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1053)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680508 sequences (100000158 bp) in 1.790 CPU sec, 1.795 real sec...
[M::mem_process_seqs] Processed 682736 reads in 163.603 CPU sec, 5.199 real sec
[M::mem_process_seqs] Processed 680780 reads in 98.632 CPU sec, 3.116 real sec
sorting block 9, #reads = 1079619 mem = 536880196 peak = 871936000
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 283580, 3, 20)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 238, 754)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1880)
[M::mem_pestat] mean and std.dev: (394.82, 297.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2443)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 328, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 927)
[M::mem_pestat] mean and std.dev: (344.16, 161.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1164)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 226, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (210.24, 78.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680600 sequences (100000245 bp) in 2.374 CPU sec, 2.497 real sec...
[M::process] read 680176 sequences (100000107 bp) in 1.698 CPU sec, 1.701 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (12, 283140, 2, 20)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 288, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (51, 496)
[M::mem_pestat] mean and std.dev: (270.91, 87.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 622)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 330, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 931)
[M::mem_pestat] mean and std.dev: (345.86, 162.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1169)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (262, 370, 413)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 715)
[M::mem_pestat] mean and std.dev: (312.24, 121.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681142 reads in 159.000 CPU sec, 5.057 real sec
sorting block 10, #reads = 1081169 mem = 536877440 peak = 871936000
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (13, 283768, 2, 19)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 448, 561)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1359)
[M::mem_pestat] mean and std.dev: (365.00, 237.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1758)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 330, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 923)
[M::mem_pestat] mean and std.dev: (345.80, 160.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1158)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 368, 483)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1081)
[M::mem_pestat] mean and std.dev: (343.58, 166.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1380)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680250 sequences (100000091 bp) in 2.218 CPU sec, 2.227 real sec...
[M::mem_process_seqs] Processed 680600 reads in 85.802 CPU sec, 2.709 real sec
[M::mem_process_seqs] Processed 680508 reads in 204.278 CPU sec, 6.482 real sec
sorting block 11, #reads = 1081035 mem = 536877344 peak = 871936000
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 283504, 3, 17)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 185, 221)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (41, 341)
[M::mem_pestat] mean and std.dev: (175.00, 48.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 401)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 332, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 928)
[M::mem_pestat] mean and std.dev: (347.53, 161.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1164)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 288, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 660)
[M::mem_pestat] mean and std.dev: (274.41, 115.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 819)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680170 sequences (100000041 bp) in 2.369 CPU sec, 2.506 real sec...
[M::process] read 680074 sequences (100000231 bp) in 1.369 CPU sec, 1.372 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 283188, 1, 17)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (298, 445, 810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1834)
[M::mem_pestat] mean and std.dev: (565.24, 315.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2346)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 332, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 930)
[M::mem_pestat] mean and std.dev: (347.55, 162.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1167)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 294, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (53, 558)
[M::mem_pestat] mean and std.dev: (275.27, 79.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 659)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680176 reads in 169.574 CPU sec, 5.397 real sec
[M::mem_process_seqs] Processed 680250 reads in 96.791 CPU sec, 3.075 real sec
sorting block 12, #reads = 1081623 mem = 536878511 peak = 871936000
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (17, 284043, 0, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 249, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (228.93, 105.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 977)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 333, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 926)
[M::mem_pestat] mean and std.dev: (348.17, 161.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1161)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 329, 557)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1329)
[M::mem_pestat] mean and std.dev: (359.68, 173.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1715)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681722 sequences (100000094 bp) in 2.489 CPU sec, 2.630 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 283796, 0, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (388, 645, 747)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1465)
[M::mem_pestat] mean and std.dev: (524.62, 209.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1824)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 334, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 929)
[M::mem_pestat] mean and std.dev: (349.45, 163.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1165)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 267, 512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1162)
[M::mem_pestat] mean and std.dev: (361.00, 202.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1487)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680170 reads in 152.330 CPU sec, 4.842 real sec
[M::process] read 681444 sequences (100000140 bp) in 1.864 CPU sec, 1.869 real sec...
sorting block 13, #reads = 1080550 mem = 536878471 peak = 871936000
[M::mem_process_seqs] Processed 680074 reads in 95.148 CPU sec, 2.999 real sec
sorting block 14, #reads = 1081030 mem = 536879243 peak = 906981376
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (8, 284441, 16, 23)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 329, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 932)
[M::mem_pestat] mean and std.dev: (344.29, 162.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1171)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (3983, 3983, 3983)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (3983, 3983)
[M::mem_pestat] mean and std.dev: (3983.00, 0.00)
[M::mem_pestat] low and high boundaries for proper pairs: (3983, 3983)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (354, 377, 483)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (96, 741)
[M::mem_pestat] mean and std.dev: (336.47, 98.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680902 sequences (100000076 bp) in 2.372 CPU sec, 2.508 real sec...
[M::process] read 680550 sequences (100000050 bp) in 1.410 CPU sec, 1.410 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 284141, 3, 18)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 218, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 808)
[M::mem_pestat] mean and std.dev: (261.47, 153.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1031)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 333, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 945)
[M::mem_pestat] mean and std.dev: (347.47, 164.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1188)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 474, 822)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2120)
[M::mem_pestat] mean and std.dev: (469.33, 321.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2769)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681722 reads in 152.680 CPU sec, 4.867 real sec
[M::mem_process_seqs] Processed 681444 reads in 94.735 CPU sec, 3.014 real sec
sorting block 15, #reads = 1082116 mem = 536879797 peak = 906981376
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 283746, 2, 11)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 404, 404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 804)
[M::mem_pestat] mean and std.dev: (307.07, 100.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1004)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 340, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 967)
[M::mem_pestat] mean and std.dev: (354.61, 167.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1216)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 203, 222)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (165, 260)
[M::mem_pestat] mean and std.dev: (202.44, 10.47)
[M::mem_pestat] low and high boundaries for proper pairs: (146, 279)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680448 sequences (100000119 bp) in 2.511 CPU sec, 2.658 real sec...
[M::process] read 680202 sequences (100000055 bp) in 1.479 CPU sec, 1.483 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (14, 283667, 0, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 243, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (24, 479)
[M::mem_pestat] mean and std.dev: (245.85, 55.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 570)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 343, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 972)
[M::mem_pestat] mean and std.dev: (357.48, 168.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1222)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 282, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 554)
[M::mem_pestat] mean and std.dev: (265.04, 88.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 671)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680902 reads in 152.024 CPU sec, 4.840 real sec
[M::mem_process_seqs] Processed 680550 reads in 95.478 CPU sec, 3.031 real sec
sorting block 16, #reads = 1083249 mem = 536878312 peak = 906981376
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 284085, 0, 5)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 255, 703)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1717)
[M::mem_pestat] mean and std.dev: (333.30, 201.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2224)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 346, 476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 982)
[M::mem_pestat] mean and std.dev: (359.88, 170.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1235)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::process] read 679656 sequences (100000156 bp) in 2.436 CPU sec, 2.594 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 284299, 4, 13)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 192, 289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 563)
[M::mem_pestat] mean and std.dev: (200.38, 67.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 700)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 346, 476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 978)
[M::mem_pestat] mean and std.dev: (359.54, 168.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1229)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 349, 389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (312.42, 109.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 824)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 679642 sequences (100000109 bp) in 1.449 CPU sec, 1.446 real sec...
[M::mem_process_seqs] Processed 680448 reads in 149.914 CPU sec, 4.778 real sec
sorting block 17, #reads = 1082477 mem = 536878802 peak = 906981376
[M::mem_process_seqs] Processed 680202 reads in 94.218 CPU sec, 2.992 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (12, 284141, 2, 16)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 314, 413)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 897)
[M::mem_pestat] mean and std.dev: (271.64, 128.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1139)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 350, 480)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 986)
[M::mem_pestat] mean and std.dev: (363.01, 169.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1239)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 268, 293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 529)
[M::mem_pestat] mean and std.dev: (208.15, 74.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 647)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680286 sequences (100000047 bp) in 2.415 CPU sec, 2.565 real sec...
[M::process] read 680824 sequences (100000014 bp) in 1.420 CPU sec, 1.420 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 283774, 5, 15)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 381, 568)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1250)
[M::mem_pestat] mean and std.dev: (435.29, 302.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1646)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 353, 483)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 993)
[M::mem_pestat] mean and std.dev: (365.10, 170.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1248)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 339, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 870)
[M::mem_pestat] mean and std.dev: (323.50, 143.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1085)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 679656 reads in 151.556 CPU sec, 4.831 real sec
sorting block 18, #reads = 1082852 mem = 536878198 peak = 906981376
[M::mem_process_seqs] Processed 679642 reads in 96.921 CPU sec, 3.079 real sec
sorting block 19, #reads = 1081655 mem = 536879982 peak = 947466240
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (16, 283822, 0, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 310, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1033)
[M::mem_pestat] mean and std.dev: (338.53, 219.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1316)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 345, 477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 983)
[M::mem_pestat] mean and std.dev: (359.64, 169.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1236)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 407, 652)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1510)
[M::mem_pestat] mean and std.dev: (362.37, 181.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1939)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680456 sequences (100000074 bp) in 2.722 CPU sec, 2.853 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (16, 283938, 9, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (131, 223, 495)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1223)
[M::mem_pestat] mean and std.dev: (277.69, 160.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1587)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 340, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 976)
[M::mem_pestat] mean and std.dev: (355.50, 168.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1228)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 286, 481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 973)
[M::mem_pestat] mean and std.dev: (298.12, 105.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1219)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680392 sequences (100000042 bp) in 1.510 CPU sec, 1.512 real sec...
[M::mem_process_seqs] Processed 680286 reads in 152.453 CPU sec, 4.846 real sec
[M::mem_process_seqs] Processed 680824 reads in 96.225 CPU sec, 3.044 real sec
sorting block 20, #reads = 1082592 mem = 536877480 peak = 947466240
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (13, 283867, 13, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 233, 289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (61, 441)
[M::mem_pestat] mean and std.dev: (238.17, 40.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 517)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 341, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 971)
[M::mem_pestat] mean and std.dev: (356.01, 168.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1221)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (655, 655, 1661)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3673)
[M::mem_pestat] mean and std.dev: (1199.62, 1054.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5420)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (268, 337, 602)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1270)
[M::mem_pestat] mean and std.dev: (402.18, 264.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1604)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680742 sequences (100000185 bp) in 2.538 CPU sec, 2.685 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (18, 283984, 0, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 230, 298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 538)
[M::mem_pestat] mean and std.dev: (238.61, 67.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 658)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 339, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 963)
[M::mem_pestat] mean and std.dev: (355.39, 167.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1210)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 278, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (271.94, 128.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 853)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680456 reads in 153.555 CPU sec, 4.885 real sec
[M::process] read 680742 sequences (100000019 bp) in 1.953 CPU sec, 1.962 real sec...
[M::mem_process_seqs] Processed 680392 reads in 97.680 CPU sec, 3.083 real sec
sorting block 21, #reads = 1081717 mem = 536880192 peak = 947466240
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (11, 283806, 3, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 270, 751)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1915)
[M::mem_pestat] mean and std.dev: (409.10, 283.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2497)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 336, 464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 954)
[M::mem_pestat] mean and std.dev: (351.47, 166.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1199)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 413, 532)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1112)
[M::mem_pestat] mean and std.dev: (347.17, 132.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1402)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680966 sequences (100000094 bp) in 2.616 CPU sec, 2.740 real sec...
[M::process] read 681150 sequences (100000247 bp) in 1.430 CPU sec, 1.428 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 283691, 0, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 360, 989)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2587)
[M::mem_pestat] mean and std.dev: (457.93, 323.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3386)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 333, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 950)
[M::mem_pestat] mean and std.dev: (349.93, 165.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1194)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 472, 650)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1462)
[M::mem_pestat] mean and std.dev: (453.52, 237.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1868)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680742 reads in 155.064 CPU sec, 4.943 real sec
sorting block 22, #reads = 1082595 mem = 536879990 peak = 947466240
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 284417, 2, 12)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (108, 172, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 546)
[M::mem_pestat] mean and std.dev: (170.53, 73.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 692)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 332, 460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 948)
[M::mem_pestat] mean and std.dev: (348.34, 164.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1192)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 250, 267)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (93, 383)
[M::mem_pestat] mean and std.dev: (213.73, 50.50)
[M::mem_pestat] low and high boundaries for proper pairs: (12, 441)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682524 sequences (100000300 bp) in 2.201 CPU sec, 2.217 real sec...
[M::mem_process_seqs] Processed 680966 reads in 87.091 CPU sec, 2.756 real sec
[M::mem_process_seqs] Processed 680742 reads in 205.454 CPU sec, 6.532 real sec
sorting block 23, #reads = 1081856 mem = 536878655 peak = 947466240
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 284235, 2, 17)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 412, 419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 911)
[M::mem_pestat] mean and std.dev: (319.36, 140.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1157)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 330, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 939)
[M::mem_pestat] mean and std.dev: (346.63, 164.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1180)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (294, 382, 680)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1452)
[M::mem_pestat] mean and std.dev: (471.35, 286.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1838)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680984 sequences (100000088 bp) in 2.744 CPU sec, 2.880 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 284451, 3, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 248, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 605)
[M::mem_pestat] mean and std.dev: (238.00, 121.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 755)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 323, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 924)
[M::mem_pestat] mean and std.dev: (339.40, 160.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1162)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (140, 224, 679)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1757)
[M::mem_pestat] mean and std.dev: (262.00, 218.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2296)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681150 reads in 172.489 CPU sec, 5.480 real sec
[M::mem_process_seqs] Processed 682524 reads in 101.560 CPU sec, 3.198 real sec
[M::process] read 680728 sequences (100000251 bp) in 2.090 CPU sec, 2.134 real sec...
sorting block 24, #reads = 1082178 mem = 536881206 peak = 947466240
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 284551, 0, 12)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 226, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 618)
[M::mem_pestat] mean and std.dev: (245.30, 129.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 764)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 332, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 943)
[M::mem_pestat] mean and std.dev: (348.57, 165.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1185)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 241, 410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 818)
[M::mem_pestat] mean and std.dev: (270.00, 130.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1022)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680500 sequences (100000122 bp) in 2.129 CPU sec, 2.294 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 284119, 1, 12)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 192, 382)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 844)
[M::mem_pestat] mean and std.dev: (280.33, 178.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1075)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 331, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 937)
[M::mem_pestat] mean and std.dev: (347.32, 163.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1177)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 391, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1050)
[M::mem_pestat] mean and std.dev: (375.50, 247.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1365)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680498 sequences (100000132 bp) in 1.730 CPU sec, 1.728 real sec...
[M::mem_process_seqs] Processed 680984 reads in 155.903 CPU sec, 4.971 real sec
sorting block 25, #reads = 1079443 mem = 536877522 peak = 947466240
[M::mem_process_seqs] Processed 680728 reads in 97.269 CPU sec, 3.081 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 283888, 5, 15)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 332, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1002)
[M::mem_pestat] mean and std.dev: (334.79, 163.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1267)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 332, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 936)
[M::mem_pestat] mean and std.dev: (348.47, 163.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1175)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 224, 529)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1231)
[M::mem_pestat] mean and std.dev: (239.08, 138.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1582)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 26, #reads = 1082003 mem = 536877620 peak = 957542400
[M::process] read 680482 sequences (100000263 bp) in 2.896 CPU sec, 3.089 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (8, 284330, 7, 14)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 330, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 926)
[M::mem_pestat] mean and std.dev: (346.33, 162.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1162)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 282, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (10, 495)
[M::mem_pestat] mean and std.dev: (243.83, 56.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 592)
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680500 reads in 152.979 CPU sec, 4.903 real sec
[M::process] read 680136 sequences (100000200 bp) in 1.536 CPU sec, 1.539 real sec...
[M::mem_process_seqs] Processed 680498 reads in 96.001 CPU sec, 3.072 real sec
sorting block 27, #reads = 1081639 mem = 536879759 peak = 957542400
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 284254, 1, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 396, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 812)
[M::mem_pestat] mean and std.dev: (333.62, 113.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1003)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 333, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 931)
[M::mem_pestat] mean and std.dev: (348.61, 163.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1168)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 367, 475)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1129)
[M::mem_pestat] mean and std.dev: (352.24, 198.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1456)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680034 sequences (100000257 bp) in 2.328 CPU sec, 2.446 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 283906, 1, 14)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 225, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1013)
[M::mem_pestat] mean and std.dev: (317.44, 180.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1292)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 335, 460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 938)
[M::mem_pestat] mean and std.dev: (350.59, 164.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1177)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 442, 812)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1992)
[M::mem_pestat] mean and std.dev: (456.86, 324.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2582)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680482 reads in 147.576 CPU sec, 4.692 real sec
[M::mem_process_seqs] Processed 680136 reads in 93.229 CPU sec, 2.930 real sec
[M::process] read 681222 sequences (100000233 bp) in 1.961 CPU sec, 1.973 real sec...
sorting block 28, #reads = 1081836 mem = 536876734 peak = 957542400
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 284287, 8, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (261, 285, 874)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2100)
[M::mem_pestat] mean and std.dev: (443.45, 320.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2713)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 338, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 942)
[M::mem_pestat] mean and std.dev: (352.90, 165.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1182)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 225, 428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 858)
[M::mem_pestat] mean and std.dev: (301.26, 169.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1073)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681578 sequences (100000160 bp) in 2.404 CPU sec, 2.510 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 284185, 0, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (107, 209, 287)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 647)
[M::mem_pestat] mean and std.dev: (212.14, 86.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 827)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 335, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 952)
[M::mem_pestat] mean and std.dev: (350.24, 166.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1197)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 218, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 577)
[M::mem_pestat] mean and std.dev: (222.39, 72.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 709)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680034 reads in 144.489 CPU sec, 4.593 real sec
[M::mem_process_seqs] Processed 681222 reads in 92.934 CPU sec, 2.931 real sec
[M::process] read 681076 sequences (100000003 bp) in 1.991 CPU sec, 2.019 real sec...
sorting block 29, #reads = 1081084 mem = 536878431 peak = 957542400
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (12, 284405, 4, 13)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (127, 337, 426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1024)
[M::mem_pestat] mean and std.dev: (246.55, 132.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1323)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 333, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 953)
[M::mem_pestat] mean and std.dev: (348.51, 165.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1199)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 215, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 614)
[M::mem_pestat] mean and std.dev: (258.33, 110.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 748)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680358 sequences (100000077 bp) in 2.100 CPU sec, 2.220 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (8, 284414, 0, 39)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 337, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 962)
[M::mem_pestat] mean and std.dev: (352.48, 167.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1210)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 339, 1833)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5081)
[M::mem_pestat] mean and std.dev: (692.33, 672.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6705)
[M::mem_pestat] skip orientation RR
[M::process] read 680188 sequences (100000096 bp) in 1.370 CPU sec, 1.364 real sec...
[M::mem_process_seqs] Processed 681578 reads in 143.852 CPU sec, 4.583 real sec
sorting block 30, #reads = 1080387 mem = 536876516 peak = 957542400
[M::process] read 679692 sequences (100000175 bp) in 1.556 CPU sec, 1.566 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 284945, 0, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 222, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1079)
[M::mem_pestat] mean and std.dev: (325.00, 185.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1385)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 343, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 963)
[M::mem_pestat] mean and std.dev: (355.98, 166.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1210)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 341, 578)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1356)
[M::mem_pestat] mean and std.dev: (341.59, 151.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1745)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680358 reads in 82.004 CPU sec, 2.795 real sec
sorting block 31, #reads = 1081853 mem = 536878788 peak = 1000579072
[M::mem_process_seqs] Processed 681076 reads in 201.018 CPU sec, 6.570 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (14, 283571, 2, 19)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 248, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684)
[M::mem_pestat] mean and std.dev: (245.69, 80.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 841)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 346, 474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 974)
[M::mem_pestat] mean and std.dev: (359.11, 168.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1224)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 240, 578)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1450)
[M::mem_pestat] mean and std.dev: (379.33, 316.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1886)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 679404 sequences (100000228 bp) in 2.378 CPU sec, 2.508 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 283665, 4, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 311, 507)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1061)
[M::mem_pestat] mean and std.dev: (360.93, 208.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1338)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 348, 478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 982)
[M::mem_pestat] mean and std.dev: (361.84, 169.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1234)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 283, 387)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667)
[M::mem_pestat] mean and std.dev: (306.26, 114.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 807)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680188 reads in 157.289 CPU sec, 5.000 real sec
sorting block 32, #reads = 1080810 mem = 536878566 peak = 1000579072
[M::mem_process_seqs] Processed 679692 reads in 92.849 CPU sec, 2.924 real sec
[M::process] read 679216 sequences (100000137 bp) in 2.034 CPU sec, 2.123 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 283218, 1, 19)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 284, 422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 866)
[M::mem_pestat] mean and std.dev: (282.83, 104.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1088)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 352, 482)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 988)
[M::mem_pestat] mean and std.dev: (365.26, 170.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1241)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 271, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 606)
[M::mem_pestat] mean and std.dev: (260.61, 79.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 742)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 33, #reads = 1080277 mem = 536879339 peak = 1000579072
[M::process] read 679646 sequences (100000157 bp) in 2.289 CPU sec, 2.413 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (14, 284001, 5, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 239, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 994)
[M::mem_pestat] mean and std.dev: (333.64, 138.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1256)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 356, 487)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1001)
[M::mem_pestat] mean and std.dev: (369.06, 173.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1258)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 287, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 509)
[M::mem_pestat] mean and std.dev: (239.28, 61.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 611)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 679404 reads in 143.559 CPU sec, 4.560 real sec
[M::mem_process_seqs] Processed 679216 reads in 92.501 CPU sec, 2.909 real sec
[M::process] read 681032 sequences (100000236 bp) in 2.082 CPU sec, 2.126 real sec...
sorting block 34, #reads = 1080241 mem = 536877179 peak = 1000579072
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (13, 284083, 3, 16)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 267, 697)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1623)
[M::mem_pestat] mean and std.dev: (443.38, 307.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2086)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 352, 483)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 993)
[M::mem_pestat] mean and std.dev: (365.64, 172.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1248)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 255, 589)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1355)
[M::mem_pestat] mean and std.dev: (351.31, 199.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1738)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680358 sequences (100000299 bp) in 2.154 CPU sec, 2.264 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 284156, 5, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 227, 400)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 864)
[M::mem_pestat] mean and std.dev: (248.00, 103.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1096)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 337, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 974)
[M::mem_pestat] mean and std.dev: (354.39, 169.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1226)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 257, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 585)
[M::mem_pestat] mean and std.dev: (262.52, 111.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 728)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 679646 reads in 147.150 CPU sec, 4.676 real sec
[M::process] read 680348 sequences (100000123 bp) in 1.832 CPU sec, 1.837 real sec...
[M::mem_process_seqs] Processed 681032 reads in 93.951 CPU sec, 2.958 real sec
sorting block 35, #reads = 1080957 mem = 536880212 peak = 1000579072
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 283971, 4, 12)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 235, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 775)
[M::mem_pestat] mean and std.dev: (251.43, 125.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 985)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 340, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 965)
[M::mem_pestat] mean and std.dev: (355.66, 168.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1213)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 372, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 986)
[M::mem_pestat] mean and std.dev: (291.25, 137.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1263)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680536 sequences (100000221 bp) in 2.508 CPU sec, 2.622 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (9, 284553, 3, 14)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 339, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 968)
[M::mem_pestat] mean and std.dev: (355.92, 169.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1217)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 468, 597)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1401)
[M::mem_pestat] mean and std.dev: (431.54, 294.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1803)
[M::mem_pestat] skip orientation RR
[M::process] read 680612 sequences (100000173 bp) in 1.429 CPU sec, 1.425 real sec...
[M::mem_process_seqs] Processed 680358 reads in 147.174 CPU sec, 4.674 real sec
[M::mem_process_seqs] Processed 680348 reads in 92.858 CPU sec, 2.936 real sec
sorting block 36, #reads = 1082821 mem = 536880660 peak = 1000579072
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (5, 284822, 5, 14)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 338, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 961)
[M::mem_pestat] mean and std.dev: (354.04, 167.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1208)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 171, 506)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1248)
[M::mem_pestat] mean and std.dev: (274.36, 179.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1619)
[M::mem_pestat] skip orientation RR
[M::process] read 680688 sequences (100000092 bp) in 2.381 CPU sec, 2.496 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 284143, 10, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 244, 517)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1239)
[M::mem_pestat] mean and std.dev: (284.93, 170.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1600)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 335, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 960)
[M::mem_pestat] mean and std.dev: (352.75, 168.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1207)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1462, 1462, 1771)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (844, 2389)
[M::mem_pestat] mean and std.dev: (1585.60, 151.38)
[M::mem_pestat] low and high boundaries for proper pairs: (535, 2698)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (271, 289, 531)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1051)
[M::mem_pestat] mean and std.dev: (425.55, 272.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1515)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680536 reads in 144.981 CPU sec, 4.603 real sec
[M::process] read 680888 sequences (100000001 bp) in 1.682 CPU sec, 1.691 real sec...
sorting block 37, #reads = 1081869 mem = 536879543 peak = 1000579072
[M::mem_process_seqs] Processed 680612 reads in 92.042 CPU sec, 2.899 real sec
sorting block 38, #reads = 1082046 mem = 536878270 peak = 1017032704
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (18, 284016, 2, 20)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 285, 1134)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3108)
[M::mem_pestat] mean and std.dev: (343.20, 332.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4095)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 335, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 953)
[M::mem_pestat] mean and std.dev: (351.15, 166.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1198)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 254, 661)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1665)
[M::mem_pestat] mean and std.dev: (388.60, 330.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2167)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681386 sequences (100000221 bp) in 2.449 CPU sec, 2.562 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (14, 284135, 2, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 306, 602)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1374)
[M::mem_pestat] mean and std.dev: (421.21, 274.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1760)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 332, 460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 946)
[M::mem_pestat] mean and std.dev: (348.95, 165.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1189)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 331, 484)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 970)
[M::mem_pestat] mean and std.dev: (336.12, 122.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1213)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680870 sequences (100000275 bp) in 1.440 CPU sec, 1.439 real sec...
[M::mem_process_seqs] Processed 680688 reads in 147.682 CPU sec, 4.690 real sec
[M::mem_process_seqs] Processed 680888 reads in 93.973 CPU sec, 2.974 real sec
sorting block 39, #reads = 1082100 mem = 536880899 peak = 1017032704
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 284212, 2, 16)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 389, 1191)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3301)
[M::mem_pestat] mean and std.dev: (579.20, 434.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4356)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 328, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 940)
[M::mem_pestat] mean and std.dev: (345.14, 164.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1182)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (267, 315, 813)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1905)
[M::mem_pestat] mean and std.dev: (414.92, 270.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2451)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680644 sequences (100000036 bp) in 2.072 CPU sec, 2.192 real sec...
[M::process] read 680552 sequences (100000004 bp) in 1.370 CPU sec, 1.374 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 284536, 4, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 199, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1024)
[M::mem_pestat] mean and std.dev: (230.62, 124.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1310)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 333, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 950)
[M::mem_pestat] mean and std.dev: (350.57, 166.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1194)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 283, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 639)
[M::mem_pestat] mean and std.dev: (292.15, 110.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 780)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681386 reads in 148.694 CPU sec, 4.734 real sec
[M::mem_process_seqs] Processed 680870 reads in 93.191 CPU sec, 2.960 real sec
sorting block 40, #reads = 1080223 mem = 536879597 peak = 1017032704
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 284383, 0, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 236, 382)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 804)
[M::mem_pestat] mean and std.dev: (253.00, 159.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1015)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 334, 464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 956)
[M::mem_pestat] mean and std.dev: (352.08, 168.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1202)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (309, 400, 631)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1275)
[M::mem_pestat] mean and std.dev: (464.28, 234.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1597)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680138 sequences (100000083 bp) in 2.416 CPU sec, 2.541 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 284241, 0, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 375, 451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 857)
[M::mem_pestat] mean and std.dev: (348.56, 128.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1060)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 335, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 951)
[M::mem_pestat] mean and std.dev: (352.00, 167.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1195)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 267, 314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 672)
[M::mem_pestat] mean and std.dev: (248.93, 98.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 851)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680462 sequences (100000156 bp) in 1.420 CPU sec, 1.419 real sec...
[M::mem_process_seqs] Processed 680644 reads in 147.765 CPU sec, 4.697 real sec
sorting block 41, #reads = 1082137 mem = 536879478 peak = 1017032704
[M::mem_process_seqs] Processed 680552 reads in 93.173 CPU sec, 2.952 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 284190, 2, 16)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 245, 405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 913)
[M::mem_pestat] mean and std.dev: (265.00, 160.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1167)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 335, 464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 954)
[M::mem_pestat] mean and std.dev: (352.26, 167.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1199)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (285, 514, 539)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1047)
[M::mem_pestat] mean and std.dev: (407.88, 144.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1301)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680084 sequences (100000202 bp) in 2.409 CPU sec, 2.509 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 284086, 5, 17)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 200, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 732)
[M::mem_pestat] mean and std.dev: (207.23, 99.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 925)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 336, 464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 952)
[M::mem_pestat] mean and std.dev: (352.93, 167.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1196)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 293, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (106, 421)
[M::mem_pestat] mean and std.dev: (232.29, 67.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 501)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680232 sequences (100000113 bp) in 1.400 CPU sec, 1.393 real sec...
[M::mem_process_seqs] Processed 680138 reads in 147.809 CPU sec, 4.694 real sec
sorting block 42, #reads = 1082559 mem = 536878651 peak = 1017032704
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 283988, 4, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 525, 534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1178)
[M::mem_pestat] mean and std.dev: (446.60, 261.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1500)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 337, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 956)
[M::mem_pestat] mean and std.dev: (354.05, 167.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1201)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 424, 538)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1160)
[M::mem_pestat] mean and std.dev: (427.12, 217.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1471)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 679796 sequences (100000262 bp) in 1.962 CPU sec, 1.968 real sec...
[M::mem_process_seqs] Processed 680084 reads in 84.275 CPU sec, 2.863 real sec
sorting block 43, #reads = 1082168 mem = 536879375 peak = 1017032704
[M::mem_process_seqs] Processed 680462 reads in 206.353 CPU sec, 6.742 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (16, 284166, 3, 18)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 352, 518)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1154)
[M::mem_pestat] mean and std.dev: (357.06, 181.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1472)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 336, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 955)
[M::mem_pestat] mean and std.dev: (353.47, 168.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1200)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 272, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 646)
[M::mem_pestat] mean and std.dev: (298.65, 145.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681356 sequences (100000279 bp) in 2.305 CPU sec, 2.437 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 284090, 9, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 209, 219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (21, 351)
[M::mem_pestat] mean and std.dev: (174.65, 43.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 417)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 340, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 958)
[M::mem_pestat] mean and std.dev: (356.13, 168.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1203)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 344, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1089)
[M::mem_pestat] mean and std.dev: (334.85, 202.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1406)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680232 reads in 158.881 CPU sec, 5.039 real sec
sorting block 44, #reads = 1080732 mem = 536882478 peak = 1017032704
[M::mem_process_seqs] Processed 679796 reads in 92.656 CPU sec, 2.916 real sec
[M::process] read 680832 sequences (100000053 bp) in 1.662 CPU sec, 1.722 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (13, 284357, 0, 11)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 281, 425)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 971)
[M::mem_pestat] mean and std.dev: (275.69, 117.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1244)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 332, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 951)
[M::mem_pestat] mean and std.dev: (348.79, 166.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1196)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (367, 367, 662)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1252)
[M::mem_pestat] mean and std.dev: (394.44, 208.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1547)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 45, #reads = 1081117 mem = 536882262 peak = 1017032704
[M::process] read 680390 sequences (100000254 bp) in 2.229 CPU sec, 2.382 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (15, 284390, 2, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 271, 425)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 811)
[M::mem_pestat] mean and std.dev: (305.86, 168.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1004)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 338, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 966)
[M::mem_pestat] mean and std.dev: (354.14, 168.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1215)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 207, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1022)
[M::mem_pestat] mean and std.dev: (251.15, 125.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1297)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 679978 sequences (100000202 bp) in 1.340 CPU sec, 1.344 real sec...
[M::mem_process_seqs] Processed 681356 reads in 146.446 CPU sec, 4.661 real sec
[M::mem_process_seqs] Processed 680832 reads in 92.797 CPU sec, 2.943 real sec
sorting block 46, #reads = 1081873 mem = 536879794 peak = 1017032704
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 284136, 1, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 281, 526)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1106)
[M::mem_pestat] mean and std.dev: (337.61, 140.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1396)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 342, 473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 977)
[M::mem_pestat] mean and std.dev: (357.32, 169.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1229)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (264, 325, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (88, 528)
[M::mem_pestat] mean and std.dev: (308.23, 63.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 616)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 679744 sequences (100000003 bp) in 2.304 CPU sec, 2.405 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 284569, 0, 5)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 212, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 652)
[M::mem_pestat] mean and std.dev: (248.39, 125.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 805)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 346, 479)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 989)
[M::mem_pestat] mean and std.dev: (361.78, 171.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1244)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::mem_process_seqs] Processed 680390 reads in 145.863 CPU sec, 4.624 real sec
[M::process] read 679572 sequences (100000212 bp) in 1.789 CPU sec, 1.793 real sec...
[M::mem_process_seqs] Processed 679978 reads in 91.824 CPU sec, 2.889 real sec
sorting block 47, #reads = 1082416 mem = 536878319 peak = 1017032704
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (5, 283783, 3, 19)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 348, 481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 993)
[M::mem_pestat] mean and std.dev: (363.51, 172.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1249)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 278, 395)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 799)
[M::mem_pestat] mean and std.dev: (274.22, 102.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1001)
[M::mem_pestat] skip orientation RR
[M::process] read 679034 sequences (100000026 bp) in 2.600 CPU sec, 2.686 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (17, 283272, 0, 14)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 242, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 708)
[M::mem_pestat] mean and std.dev: (290.56, 170.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 974)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 349, 481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 991)
[M::mem_pestat] mean and std.dev: (363.47, 171.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1246)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 236, 425)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 879)
[M::mem_pestat] mean and std.dev: (247.92, 105.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1106)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 679744 reads in 141.608 CPU sec, 4.487 real sec
[M::mem_process_seqs] Processed 679572 reads in 89.735 CPU sec, 2.816 real sec
[M::process] read 678630 sequences (100000298 bp) in 1.898 CPU sec, 1.917 real sec...
sorting block 48, #reads = 1081757 mem = 536882333 peak = 1017032704
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 283695, 1, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 291, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 582)
[M::mem_pestat] mean and std.dev: (238.62, 71.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 717)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 354, 484)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 992)
[M::mem_pestat] mean and std.dev: (367.08, 171.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1246)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 279, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (253.28, 116.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 860)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 679516 sequences (100000073 bp) in 2.299 CPU sec, 2.408 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 283169, 1, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (284, 315, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (222, 377)
[M::mem_pestat] mean and std.dev: (301.41, 14.87)
[M::mem_pestat] low and high boundaries for proper pairs: (191, 408)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 356, 488)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1002)
[M::mem_pestat] mean and std.dev: (369.84, 172.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1259)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 280, 424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 780)
[M::mem_pestat] mean and std.dev: (297.00, 116.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 958)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 679034 reads in 142.978 CPU sec, 4.544 real sec
sorting block 49, #reads = 1081909 mem = 536878354 peak = 1017032704
[M::mem_process_seqs] Processed 678630 reads in 91.296 CPU sec, 2.866 real sec
[M::process] read 680718 sequences (100000001 bp) in 1.938 CPU sec, 1.972 real sec...
sorting block 50, #reads = 1081940 mem = 536877071 peak = 1025568768
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (15, 283102, 0, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 241, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1019)
[M::mem_pestat] mean and std.dev: (304.60, 176.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1300)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 352, 483)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 995)
[M::mem_pestat] mean and std.dev: (365.60, 172.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1251)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 235, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 967)
[M::mem_pestat] mean and std.dev: (326.12, 201.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1222)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680114 sequences (100000083 bp) in 2.380 CPU sec, 2.474 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 283441, 1, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (254, 394, 553)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1151)
[M::mem_pestat] mean and std.dev: (404.17, 214.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1450)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 339, 474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 984)
[M::mem_pestat] mean and std.dev: (356.67, 171.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1239)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 291, 481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 971)
[M::mem_pestat] mean and std.dev: (354.64, 195.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1216)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680088 sequences (100000038 bp) in 1.350 CPU sec, 1.353 real sec...
[M::mem_process_seqs] Processed 679516 reads in 147.368 CPU sec, 4.685 real sec
[M::mem_process_seqs] Processed 680718 reads in 93.579 CPU sec, 2.964 real sec
sorting block 51, #reads = 1082578 mem = 536879821 peak = 1025568768
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 283663, 11, 19)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 324, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684)
[M::mem_pestat] mean and std.dev: (287.67, 120.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 847)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 344, 477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 985)
[M::mem_pestat] mean and std.dev: (359.68, 170.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1239)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1602, 1752, 1988)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (830, 2760)
[M::mem_pestat] mean and std.dev: (1687.78, 357.36)
[M::mem_pestat] low and high boundaries for proper pairs: (258, 3146)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (261, 468, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 891)
[M::mem_pestat] mean and std.dev: (393.89, 131.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1101)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680348 sequences (100000210 bp) in 1.993 CPU sec, 2.087 real sec...
[M::process] read 680716 sequences (100000298 bp) in 1.606 CPU sec, 1.619 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 283925, 2, 17)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 204, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1003)
[M::mem_pestat] mean and std.dev: (282.04, 184.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1277)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 340, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 968)
[M::mem_pestat] mean and std.dev: (355.75, 168.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1217)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (102, 168, 407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1017)
[M::mem_pestat] mean and std.dev: (244.40, 212.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1322)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680114 reads in 148.555 CPU sec, 4.719 real sec
[M::mem_process_seqs] Processed 680088 reads in 93.089 CPU sec, 2.942 real sec
sorting block 52, #reads = 1081489 mem = 536878102 peak = 1025568768
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 283599, 4, 20)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 335, 599)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1417)
[M::mem_pestat] mean and std.dev: (396.04, 244.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1826)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 337, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 963)
[M::mem_pestat] mean and std.dev: (353.56, 167.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1211)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 216, 277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 505)
[M::mem_pestat] mean and std.dev: (236.75, 75.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 619)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680690 sequences (100000008 bp) in 2.561 CPU sec, 2.653 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 283735, 2, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (119, 224, 405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 977)
[M::mem_pestat] mean and std.dev: (277.00, 233.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1263)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 334, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 959)
[M::mem_pestat] mean and std.dev: (351.14, 166.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1206)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 470, 669)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1497)
[M::mem_pestat] mean and std.dev: (488.79, 292.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1911)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680590 sequences (100000172 bp) in 1.790 CPU sec, 1.786 real sec...
[M::mem_process_seqs] Processed 680348 reads in 158.783 CPU sec, 5.031 real sec
sorting block 53, #reads = 1081157 mem = 536877849 peak = 1025568768
[M::mem_process_seqs] Processed 680716 reads in 100.652 CPU sec, 3.191 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (11, 283734, 3, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 329, 415)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 909)
[M::mem_pestat] mean and std.dev: (279.09, 124.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1156)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 333, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 955)
[M::mem_pestat] mean and std.dev: (350.07, 165.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1201)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 297, 532)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1262)
[M::mem_pestat] mean and std.dev: (339.20, 200.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1627)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680492 sequences (100000229 bp) in 2.134 CPU sec, 2.227 real sec...
[M::process] read 680466 sequences (100000236 bp) in 1.520 CPU sec, 1.524 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 283494, 0, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 227, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 713)
[M::mem_pestat] mean and std.dev: (239.93, 90.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 888)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 334, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 950)
[M::mem_pestat] mean and std.dev: (350.01, 165.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1194)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 293, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (72, 487)
[M::mem_pestat] mean and std.dev: (273.89, 78.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 589)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680690 reads in 157.624 CPU sec, 5.016 real sec
sorting block 54, #reads = 1081074 mem = 536877584 peak = 1025568768
[M::mem_process_seqs] Processed 680590 reads in 100.786 CPU sec, 3.194 real sec
sorting block 55, #reads = 1081755 mem = 536878735 peak = 1068331008
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (10, 283816, 1, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 1943, 1947)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5357)
[M::mem_pestat] mean and std.dev: (931.12, 795.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7062)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 335, 464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 954)
[M::mem_pestat] mean and std.dev: (351.51, 165.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1199)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 262, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 620)
[M::mem_pestat] mean and std.dev: (261.67, 83.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 762)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680642 sequences (100000286 bp) in 2.620 CPU sec, 2.719 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (14, 284195, 4, 19)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 349, 419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 815)
[M::mem_pestat] mean and std.dev: (349.57, 157.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1013)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 335, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 962)
[M::mem_pestat] mean and std.dev: (351.86, 166.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1210)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 372, 549)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1187)
[M::mem_pestat] mean and std.dev: (343.00, 140.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1506)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680498 sequences (100000086 bp) in 1.908 CPU sec, 1.906 real sec...
[M::mem_process_seqs] Processed 680492 reads in 157.315 CPU sec, 4.977 real sec
[M::mem_process_seqs] Processed 680466 reads in 98.361 CPU sec, 3.104 real sec
sorting block 56, #reads = 1081377 mem = 536877965 peak = 1068331008
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (13, 284132, 8, 20)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 227, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 669)
[M::mem_pestat] mean and std.dev: (257.85, 126.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 839)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 334, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 964)
[M::mem_pestat] mean and std.dev: (351.78, 167.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1213)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 383, 719)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1673)
[M::mem_pestat] mean and std.dev: (485.70, 346.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2150)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680126 sequences (100000078 bp) in 2.370 CPU sec, 2.464 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 284285, 0, 14)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 328, 540)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1276)
[M::mem_pestat] mean and std.dev: (374.96, 212.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1644)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 333, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 955)
[M::mem_pestat] mean and std.dev: (350.68, 166.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1201)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 256, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 911)
[M::mem_pestat] mean and std.dev: (297.42, 96.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1137)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680642 reads in 153.379 CPU sec, 4.865 real sec
[M::process] read 679978 sequences (100000021 bp) in 1.820 CPU sec, 1.818 real sec...
[M::mem_process_seqs] Processed 680498 reads in 97.874 CPU sec, 3.083 real sec
sorting block 57, #reads = 1081877 mem = 536878871 peak = 1068331008
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 283681, 2, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 267, 377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 799)
[M::mem_pestat] mean and std.dev: (235.50, 95.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1010)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 335, 464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 952)
[M::mem_pestat] mean and std.dev: (352.10, 166.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1196)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 319, 388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 814)
[M::mem_pestat] mean and std.dev: (310.56, 168.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1027)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 679730 sequences (100000133 bp) in 2.679 CPU sec, 2.769 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 283675, 3, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 190, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (58, 388)
[M::mem_pestat] mean and std.dev: (195.50, 45.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 454)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 337, 464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 948)
[M::mem_pestat] mean and std.dev: (352.74, 165.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1190)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 320, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 832)
[M::mem_pestat] mean and std.dev: (265.00, 76.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1033)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680126 reads in 147.214 CPU sec, 4.656 real sec
[M::process] read 679656 sequences (100000266 bp) in 1.855 CPU sec, 1.863 real sec...
[M::mem_process_seqs] Processed 679978 reads in 94.658 CPU sec, 2.978 real sec
sorting block 58, #reads = 1081405 mem = 536878080 peak = 1068331008
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 284526, 4, 20)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 281, 975)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2521)
[M::mem_pestat] mean and std.dev: (387.10, 359.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3294)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 340, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 953)
[M::mem_pestat] mean and std.dev: (355.69, 166.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1196)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 298, 705)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1749)
[M::mem_pestat] mean and std.dev: (452.20, 342.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2271)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 59, #reads = 1081044 mem = 536878153 peak = 1068331008
[M::process] read 679422 sequences (100000063 bp) in 2.300 CPU sec, 2.416 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 284020, 0, 18)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 224, 310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 662)
[M::mem_pestat] mean and std.dev: (237.38, 123.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 838)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 340, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 960)
[M::mem_pestat] mean and std.dev: (355.82, 167.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1206)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 228, 291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 547)
[M::mem_pestat] mean and std.dev: (240.56, 105.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 675)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 679730 reads in 146.979 CPU sec, 4.673 real sec
[M::mem_process_seqs] Processed 679656 reads in 93.910 CPU sec, 2.958 real sec
[M::process] read 685948 sequences (100000106 bp) in 2.126 CPU sec, 2.146 real sec...
sorting block 60, #reads = 1081902 mem = 536882851 peak = 1068331008
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (18, 284222, 7, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 219, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 784)
[M::mem_pestat] mean and std.dev: (254.88, 139.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 999)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 342, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 960)
[M::mem_pestat] mean and std.dev: (357.88, 167.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1205)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 289, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (10, 525)
[M::mem_pestat] mean and std.dev: (258.08, 87.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 628)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 684988 sequences (100000141 bp) in 2.269 CPU sec, 2.352 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (11, 286173, 3, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (276, 525, 656)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1416)
[M::mem_pestat] mean and std.dev: (429.90, 206.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1796)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 307, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 940)
[M::mem_pestat] mean and std.dev: (330.36, 164.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1188)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 477, 842)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2068)
[M::mem_pestat] mean and std.dev: (516.08, 365.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2681)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 685056 sequences (100000201 bp) in 1.726 CPU sec, 1.728 real sec...
[M::mem_process_seqs] Processed 679422 reads in 153.849 CPU sec, 4.889 real sec
[M::process] read 684244 sequences (100000189 bp) in 1.559 CPU sec, 1.579 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (14, 285749, 2, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 389, 389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 795)
[M::mem_pestat] mean and std.dev: (359.64, 215.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1220)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 313, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 961)
[M::mem_pestat] mean and std.dev: (335.90, 166.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1215)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 366, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 910)
[M::mem_pestat] mean and std.dev: (316.39, 114.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1147)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684988 reads in 86.819 CPU sec, 2.764 real sec
sorting block 61, #reads = 1080820 mem = 536879298 peak = 1068331008
[M::mem_process_seqs] Processed 685948 reads in 211.159 CPU sec, 6.706 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 285694, 1, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 335, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (32, 537)
[M::mem_pestat] mean and std.dev: (290.68, 87.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 639)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 314, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 947)
[M::mem_pestat] mean and std.dev: (334.30, 163.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1196)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 328, 488)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1156)
[M::mem_pestat] mean and std.dev: (311.90, 152.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1490)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 62, #reads = 1080969 mem = 536879248 peak = 1068331008
[M::process] read 682906 sequences (100000178 bp) in 2.934 CPU sec, 3.105 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (14, 285560, 6, 14)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (132, 228, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 642)
[M::mem_pestat] mean and std.dev: (233.79, 83.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 812)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 320, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 959)
[M::mem_pestat] mean and std.dev: (338.00, 163.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1211)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 207, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 672)
[M::mem_pestat] mean and std.dev: (258.07, 124.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 685056 reads in 179.537 CPU sec, 5.707 real sec
[M::process] read 682656 sequences (100000263 bp) in 1.609 CPU sec, 1.632 real sec...
[M::mem_process_seqs] Processed 684244 reads in 104.046 CPU sec, 3.283 real sec
sorting block 63, #reads = 1080366 mem = 536880365 peak = 1068331008
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 285205, 0, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 306, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 663)
[M::mem_pestat] mean and std.dev: (262.40, 84.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 815)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 328, 460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 964)
[M::mem_pestat] mean and std.dev: (343.94, 164.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1216)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (306, 395, 530)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 978)
[M::mem_pestat] mean and std.dev: (412.29, 167.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1202)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683168 sequences (100000054 bp) in 2.995 CPU sec, 3.216 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 285022, 3, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 209, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 722)
[M::mem_pestat] mean and std.dev: (228.86, 81.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 912)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 330, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 969)
[M::mem_pestat] mean and std.dev: (345.78, 165.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1222)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 328, 492)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 982)
[M::mem_pestat] mean and std.dev: (359.21, 162.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1227)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682906 reads in 170.865 CPU sec, 5.496 real sec
[M::process] read 684996 sequences (100000131 bp) in 1.991 CPU sec, 2.068 real sec...
[M::mem_process_seqs] Processed 682656 reads in 112.010 CPU sec, 3.616 real sec
sorting block 64, #reads = 1079650 mem = 536879605 peak = 1068331008
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 284730, 2, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 267, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 611)
[M::mem_pestat] mean and std.dev: (218.17, 81.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 767)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 327, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 958)
[M::mem_pestat] mean and std.dev: (342.65, 163.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1208)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 217, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 832)
[M::mem_pestat] mean and std.dev: (247.74, 173.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1064)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 685336 sequences (100000032 bp) in 2.508 CPU sec, 2.804 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 285581, 1, 18)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 228, 389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 821)
[M::mem_pestat] mean and std.dev: (250.17, 145.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1037)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 313, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 938)
[M::mem_pestat] mean and std.dev: (332.91, 162.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1184)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 305, 425)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 923)
[M::mem_pestat] mean and std.dev: (303.06, 152.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1172)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 685122 sequences (100000151 bp) in 1.783 CPU sec, 1.844 real sec...
[M::mem_process_seqs] Processed 683168 reads in 177.588 CPU sec, 5.722 real sec
sorting block 65, #reads = 1079359 mem = 536877984 peak = 1068331008
[M::mem_process_seqs] Processed 684996 reads in 113.722 CPU sec, 3.632 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (18, 286089, 1, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 342, 417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (335.06, 124.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 924)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 311, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 936)
[M::mem_pestat] mean and std.dev: (330.50, 161.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1182)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (275, 386, 3809)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10877)
[M::mem_pestat] mean and std.dev: (1260.59, 1567.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14411)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 66, #reads = 1078943 mem = 536877590 peak = 1068331008
[M::process] read 684794 sequences (100000104 bp) in 2.576 CPU sec, 3.039 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (17, 286194, 1, 20)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 194, 833)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2149)
[M::mem_pestat] mean and std.dev: (334.60, 257.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2807)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 312, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 939)
[M::mem_pestat] mean and std.dev: (331.29, 161.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1186)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 371, 581)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1313)
[M::mem_pestat] mean and std.dev: (416.55, 293.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1679)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683292 sequences (100000046 bp) in 1.826 CPU sec, 1.836 real sec...
[M::mem_process_seqs] Processed 685336 reads in 185.593 CPU sec, 5.995 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 285694, 3, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 385, 826)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2108)
[M::mem_pestat] mean and std.dev: (385.30, 290.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2749)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 314, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 938)
[M::mem_pestat] mean and std.dev: (332.83, 161.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1184)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 278, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (265.68, 111.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682994 sequences (100000225 bp) in 2.204 CPU sec, 2.230 real sec...
[M::mem_process_seqs] Processed 684794 reads in 111.665 CPU sec, 3.796 real sec
sorting block 67, #reads = 1077673 mem = 536880596 peak = 1068331008
[M::mem_process_seqs] Processed 685122 reads in 264.538 CPU sec, 8.736 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 285083, 3, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (252, 395, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 807)
[M::mem_pestat] mean and std.dev: (367.62, 136.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 992)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 321, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 947)
[M::mem_pestat] mean and std.dev: (339.02, 162.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1194)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 352, 433)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 873)
[M::mem_pestat] mean and std.dev: (292.32, 105.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1093)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 686180 sequences (100000184 bp) in 2.640 CPU sec, 2.948 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (18, 285055, 10, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (109, 223, 769)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2089)
[M::mem_pestat] mean and std.dev: (436.94, 392.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2749)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 324, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 949)
[M::mem_pestat] mean and std.dev: (340.83, 162.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1196)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (360, 588, 650)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1230)
[M::mem_pestat] mean and std.dev: (488.56, 161.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1520)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 258, 648)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1586)
[M::mem_pestat] mean and std.dev: (330.68, 237.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2055)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683292 reads in 204.507 CPU sec, 6.576 real sec
sorting block 68, #reads = 1077883 mem = 536879643 peak = 1068331008
[M::process] read 683822 sequences (100000023 bp) in 2.023 CPU sec, 2.041 real sec...
[M::mem_process_seqs] Processed 682994 reads in 120.281 CPU sec, 3.929 real sec
sorting block 69, #reads = 1079341 mem = 536881838 peak = 1068331008
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 286297, 5, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 235, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 600)
[M::mem_pestat] mean and std.dev: (227.27, 65.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 741)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 304, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 903)
[M::mem_pestat] mean and std.dev: (322.20, 154.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1139)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 240, 558)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1278)
[M::mem_pestat] mean and std.dev: (366.88, 255.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1638)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682922 sequences (100000241 bp) in 2.519 CPU sec, 2.916 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (11, 285629, 5, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 638, 754)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1970)
[M::mem_pestat] mean and std.dev: (413.90, 290.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2578)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 316, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 924)
[M::mem_pestat] mean and std.dev: (332.18, 157.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1164)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 335, 495)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1055)
[M::mem_pestat] mean and std.dev: (314.04, 149.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1335)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682890 sequences (100000139 bp) in 2.089 CPU sec, 2.096 real sec...
[M::mem_process_seqs] Processed 686180 reads in 209.438 CPU sec, 6.739 real sec
[M::mem_process_seqs] Processed 683822 reads in 137.192 CPU sec, 4.363 real sec
sorting block 70, #reads = 1073432 mem = 536878948 peak = 1068331008
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 285039, 7, 14)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 357, 2284)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6366)
[M::mem_pestat] mean and std.dev: (822.95, 882.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8407)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 321, 451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 939)
[M::mem_pestat] mean and std.dev: (338.14, 160.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1183)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 305, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 703)
[M::mem_pestat] mean and std.dev: (258.08, 92.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 887)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682622 sequences (100000271 bp) in 2.311 CPU sec, 2.467 real sec...
[M::process] read 683154 sequences (100000244 bp) in 1.994 CPU sec, 2.010 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 286024, 3, 12)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 283, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 591)
[M::mem_pestat] mean and std.dev: (234.40, 75.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 728)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 323, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 943)
[M::mem_pestat] mean and std.dev: (339.85, 161.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1188)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 220, 500)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1190)
[M::mem_pestat] mean and std.dev: (243.64, 131.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1535)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682922 reads in 189.724 CPU sec, 6.108 real sec
[M::mem_process_seqs] Processed 682890 reads in 123.292 CPU sec, 3.958 real sec
sorting block 71, #reads = 1075380 mem = 536878407 peak = 1068331008
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 284965, 2, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 307, 416)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 952)
[M::mem_pestat] mean and std.dev: (295.71, 137.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1220)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 326, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 954)
[M::mem_pestat] mean and std.dev: (342.86, 163.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1202)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 241, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 678)
[M::mem_pestat] mean and std.dev: (240.00, 90.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 839)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682472 sequences (100000257 bp) in 2.164 CPU sec, 2.282 real sec...
[M::process] read 688612 sequences (100000107 bp) in 1.666 CPU sec, 1.672 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 285580, 3, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 220, 423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 923)
[M::mem_pestat] mean and std.dev: (331.57, 214.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1191)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 321, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 942)
[M::mem_pestat] mean and std.dev: (339.14, 162.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1187)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 335, 580)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1280)
[M::mem_pestat] mean and std.dev: (306.94, 119.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1630)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682622 reads in 191.548 CPU sec, 6.199 real sec
sorting block 72, #reads = 1075947 mem = 536880871 peak = 1068331008
[M::mem_process_seqs] Processed 683154 reads in 124.923 CPU sec, 4.026 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (18, 285484, 4, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 306, 706)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1734)
[M::mem_pestat] mean and std.dev: (420.28, 257.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2248)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 326, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 965)
[M::mem_pestat] mean and std.dev: (344.71, 166.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1217)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 318, 986)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2592)
[M::mem_pestat] mean and std.dev: (551.93, 503.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3395)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 73, #reads = 1074101 mem = 536880331 peak = 1068331008
[M::process] read 687246 sequences (100000090 bp) in 2.553 CPU sec, 2.746 real sec...
[M::process] read 686168 sequences (100000124 bp) in 1.947 CPU sec, 1.974 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (16, 287069, 2, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 253, 415)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 931)
[M::mem_pestat] mean and std.dev: (316.06, 211.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1189)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 291, 423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 895)
[M::mem_pestat] mean and std.dev: (314.97, 157.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1131)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (278, 379, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (353.20, 120.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 922)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682472 reads in 199.088 CPU sec, 6.490 real sec
[M::mem_process_seqs] Processed 688612 reads in 134.473 CPU sec, 4.367 real sec
sorting block 74, #reads = 1075020 mem = 536877052 peak = 1068331008
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (17, 286761, 4, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 194, 269)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 473)
[M::mem_pestat] mean and std.dev: (180.21, 53.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 575)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 298, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 908)
[M::mem_pestat] mean and std.dev: (320.14, 157.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1147)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 735)
[M::mem_pestat] mean and std.dev: (241.22, 95.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 925)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 685216 sequences (100000127 bp) in 2.313 CPU sec, 2.553 real sec...
[M::process] read 684478 sequences (100000290 bp) in 1.789 CPU sec, 1.797 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 286614, 2, 15)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 213, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 488)
[M::mem_pestat] mean and std.dev: (218.43, 79.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 595)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 305, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 921)
[M::mem_pestat] mean and std.dev: (325.51, 159.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1163)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 321, 383)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 801)
[M::mem_pestat] mean and std.dev: (266.79, 118.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1010)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 687246 reads in 192.364 CPU sec, 6.322 real sec
[M::mem_process_seqs] Processed 686168 reads in 123.383 CPU sec, 4.014 real sec
sorting block 75, #reads = 1074651 mem = 536884870 peak = 1068331008
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (15, 286427, 3, 20)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (252, 263, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (30, 585)
[M::mem_pestat] mean and std.dev: (274.07, 84.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 696)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 311, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 931)
[M::mem_pestat] mean and std.dev: (329.56, 159.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1175)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 196, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (272.85, 166.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 939)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683292 sequences (100000164 bp) in 2.719 CPU sec, 2.948 real sec...
[M::process] read 684502 sequences (100000235 bp) in 1.780 CPU sec, 1.817 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 286614, 1, 20)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 270, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 735)
[M::mem_pestat] mean and std.dev: (273.54, 125.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 920)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 318, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 940)
[M::mem_pestat] mean and std.dev: (334.31, 160.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1186)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 146, 284)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 596)
[M::mem_pestat] mean and std.dev: (203.10, 90.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 752)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 685216 reads in 190.986 CPU sec, 6.250 real sec
[M::mem_process_seqs] Processed 684478 reads in 119.643 CPU sec, 3.901 real sec
sorting block 76, #reads = 1075802 mem = 536886767 peak = 1068331008
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 285366, 3, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 196, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 618)
[M::mem_pestat] mean and std.dev: (205.50, 98.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 776)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 324, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 945)
[M::mem_pestat] mean and std.dev: (339.64, 161.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1191)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 191, 298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 536)
[M::mem_pestat] mean and std.dev: (244.05, 86.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 655)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 684800 sequences (100000092 bp) in 2.538 CPU sec, 2.916 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (16, 285836, 4, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (131, 199, 412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 974)
[M::mem_pestat] mean and std.dev: (232.36, 153.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1255)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 314, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 936)
[M::mem_pestat] mean and std.dev: (333.17, 161.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1181)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 332, 421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 919)
[M::mem_pestat] mean and std.dev: (352.08, 186.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1168)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683292 reads in 176.013 CPU sec, 5.739 real sec
sorting block 77, #reads = 1076939 mem = 536880076 peak = 1068331008
[M::process] read 684570 sequences (100000221 bp) in 2.020 CPU sec, 2.047 real sec...
[M::mem_process_seqs] Processed 684502 reads in 109.848 CPU sec, 3.490 real sec
sorting block 78, #reads = 1077811 mem = 536883661 peak = 1068331008
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 285822, 3, 17)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 283, 413)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 837)
[M::mem_pestat] mean and std.dev: (271.57, 111.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1049)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 313, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 935)
[M::mem_pestat] mean and std.dev: (332.13, 161.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1180)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 335, 400)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 720)
[M::mem_pestat] mean and std.dev: (307.06, 104.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 880)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683928 sequences (100000260 bp) in 2.761 CPU sec, 2.855 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (17, 285974, 2, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 186, 429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 981)
[M::mem_pestat] mean and std.dev: (229.67, 124.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1257)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 314, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 933)
[M::mem_pestat] mean and std.dev: (332.76, 161.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1177)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 318, 647)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1445)
[M::mem_pestat] mean and std.dev: (404.12, 233.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1844)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 684488 sequences (100000148 bp) in 1.900 CPU sec, 1.904 real sec...
[M::mem_process_seqs] Processed 684800 reads in 166.545 CPU sec, 5.273 real sec
[M::mem_process_seqs] Processed 684570 reads in 106.461 CPU sec, 3.362 real sec
sorting block 79, #reads = 1079015 mem = 536879121 peak = 1068331008
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 285990, 1, 13)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 263, 834)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2212)
[M::mem_pestat] mean and std.dev: (564.40, 671.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3249)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 317, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 941)
[M::mem_pestat] mean and std.dev: (335.81, 162.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1187)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 288, 378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 720)
[M::mem_pestat] mean and std.dev: (291.77, 137.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 891)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683650 sequences (100000145 bp) in 2.423 CPU sec, 2.522 real sec...
[M::process] read 686132 sequences (100000081 bp) in 1.970 CPU sec, 1.975 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 286467, 8, 18)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 172, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 769)
[M::mem_pestat] mean and std.dev: (251.08, 157.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 974)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 315, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 934)
[M::mem_pestat] mean and std.dev: (333.64, 161.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1178)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 281, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 710)
[M::mem_pestat] mean and std.dev: (260.20, 129.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 892)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683928 reads in 175.828 CPU sec, 5.584 real sec
[M::mem_process_seqs] Processed 684488 reads in 115.454 CPU sec, 3.654 real sec
sorting block 80, #reads = 1078927 mem = 536877855 peak = 1068331008
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (15, 285846, 3, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 320, 553)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1283)
[M::mem_pestat] mean and std.dev: (331.54, 183.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1648)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 319, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 940)
[M::mem_pestat] mean and std.dev: (337.34, 162.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1185)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 341, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 927)
[M::mem_pestat] mean and std.dev: (304.38, 123.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1170)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682114 sequences (100000038 bp) in 2.813 CPU sec, 2.922 real sec...
[M::process] read 682276 sequences (100000049 bp) in 1.959 CPU sec, 1.953 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 286858, 3, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 230, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 798)
[M::mem_pestat] mean and std.dev: (235.21, 92.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1010)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 304, 434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 910)
[M::mem_pestat] mean and std.dev: (324.77, 158.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1148)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 513, 1374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3706)
[M::mem_pestat] mean and std.dev: (689.92, 559.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4872)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683650 reads in 189.277 CPU sec, 6.012 real sec
sorting block 81, #reads = 1077525 mem = 536879448 peak = 1068331008
[M::mem_process_seqs] Processed 686132 reads in 126.810 CPU sec, 4.019 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (11, 285107, 3, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 142, 217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 367)
[M::mem_pestat] mean and std.dev: (157.73, 41.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 442)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 328, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 965)
[M::mem_pestat] mean and std.dev: (347.38, 167.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1216)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 214, 289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 563)
[M::mem_pestat] mean and std.dev: (208.04, 61.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 700)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682000 sequences (100000004 bp) in 2.283 CPU sec, 2.384 real sec...
[M::process] read 681402 sequences (100000264 bp) in 1.618 CPU sec, 1.621 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (16, 285039, 3, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 166, 532)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1330)
[M::mem_pestat] mean and std.dev: (381.19, 359.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1818)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 329, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 976)
[M::mem_pestat] mean and std.dev: (348.38, 168.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1231)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 270, 400)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 826)
[M::mem_pestat] mean and std.dev: (324.21, 162.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1039)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682114 reads in 178.898 CPU sec, 5.703 real sec
sorting block 82, #reads = 1073541 mem = 536880262 peak = 1068331008
[M::mem_process_seqs] Processed 682276 reads in 115.917 CPU sec, 3.687 real sec
sorting block 83, #reads = 1078726 mem = 536878235 peak = 1123155968
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 285323, 1, 17)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (128, 172, 281)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 587)
[M::mem_pestat] mean and std.dev: (206.25, 87.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 740)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 331, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 983)
[M::mem_pestat] mean and std.dev: (350.50, 170.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1240)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 234, 484)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1132)
[M::mem_pestat] mean and std.dev: (270.20, 145.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1456)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681230 sequences (100000060 bp) in 2.677 CPU sec, 2.791 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (13, 284572, 5, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 194, 393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 853)
[M::mem_pestat] mean and std.dev: (247.50, 162.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1083)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 336, 476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 998)
[M::mem_pestat] mean and std.dev: (355.46, 173.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1259)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 206, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (236.44, 119.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 873)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681302 sequences (100000076 bp) in 1.832 CPU sec, 1.835 real sec...
[M::mem_process_seqs] Processed 682000 reads in 179.064 CPU sec, 5.699 real sec
[M::mem_process_seqs] Processed 681402 reads in 114.676 CPU sec, 3.630 real sec
sorting block 84, #reads = 1079002 mem = 536878343 peak = 1123155968
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 284272, 4, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 315, 556)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1240)
[M::mem_pestat] mean and std.dev: (354.80, 188.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1582)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 338, 477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 999)
[M::mem_pestat] mean and std.dev: (357.37, 174.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1260)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (290, 390, 576)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1148)
[M::mem_pestat] mean and std.dev: (343.89, 148.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1434)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681330 sequences (100000098 bp) in 2.352 CPU sec, 2.481 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (13, 284374, 0, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 213, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709)
[M::mem_pestat] mean and std.dev: (231.25, 97.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 890)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 337, 476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 998)
[M::mem_pestat] mean and std.dev: (357.02, 174.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1259)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 333, 635)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1463)
[M::mem_pestat] mean and std.dev: (359.52, 197.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1877)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 685354 sequences (100000245 bp) in 1.980 CPU sec, 1.982 real sec...
[M::mem_process_seqs] Processed 681230 reads in 176.865 CPU sec, 5.633 real sec
[M::mem_process_seqs] Processed 681302 reads in 116.180 CPU sec, 3.671 real sec
sorting block 85, #reads = 1079118 mem = 536879664 peak = 1123155968
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 284585, 6, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 383, 551)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1167)
[M::mem_pestat] mean and std.dev: (391.31, 229.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1475)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 337, 479)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1005)
[M::mem_pestat] mean and std.dev: (357.83, 175.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1268)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 303, 613)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1555)
[M::mem_pestat] mean and std.dev: (384.48, 261.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2026)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683528 sequences (100000159 bp) in 2.676 CPU sec, 2.790 real sec...
[M::process] read 683194 sequences (100000104 bp) in 1.940 CPU sec, 1.943 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 286086, 4, 15)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 301, 561)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1311)
[M::mem_pestat] mean and std.dev: (301.79, 163.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1686)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 311, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 960)
[M::mem_pestat] mean and std.dev: (335.91, 169.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1214)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 228, 405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 941)
[M::mem_pestat] mean and std.dev: (220.92, 103.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1209)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681330 reads in 192.201 CPU sec, 6.115 real sec
sorting block 86, #reads = 1076913 mem = 536879627 peak = 1123155968
[M::mem_process_seqs] Processed 685354 reads in 126.385 CPU sec, 4.015 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (16, 285238, 2, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 237, 425)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 957)
[M::mem_pestat] mean and std.dev: (240.14, 112.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1223)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 324, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 985)
[M::mem_pestat] mean and std.dev: (345.94, 172.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1245)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (285, 375, 525)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1005)
[M::mem_pestat] mean and std.dev: (362.74, 124.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1245)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 87, #reads = 1074372 mem = 536877606 peak = 1123155968
[M::process] read 682962 sequences (100000142 bp) in 2.473 CPU sec, 2.588 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 285374, 1, 16)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 235, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 598)
[M::mem_pestat] mean and std.dev: (264.19, 99.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 719)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 328, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 984)
[M::mem_pestat] mean and std.dev: (347.79, 171.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1243)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 242, 284)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (92, 412)
[M::mem_pestat] mean and std.dev: (229.58, 43.68)
[M::mem_pestat] low and high boundaries for proper pairs: (28, 476)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681536 sequences (100000155 bp) in 1.881 CPU sec, 1.889 real sec...
[M::mem_process_seqs] Processed 683528 reads in 168.542 CPU sec, 5.360 real sec
[M::mem_process_seqs] Processed 683194 reads in 109.804 CPU sec, 3.466 real sec
sorting block 88, #reads = 1082672 mem = 536880464 peak = 1123155968
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 285608, 1, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 500, 570)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1314)
[M::mem_pestat] mean and std.dev: (524.00, 343.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1898)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 328, 464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 974)
[M::mem_pestat] mean and std.dev: (347.23, 170.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1229)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 337, 744)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1870)
[M::mem_pestat] mean and std.dev: (354.45, 350.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2433)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681316 sequences (100000197 bp) in 2.441 CPU sec, 2.553 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (16, 285248, 2, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 483, 549)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1257)
[M::mem_pestat] mean and std.dev: (443.56, 254.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1611)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 337, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 975)
[M::mem_pestat] mean and std.dev: (353.51, 170.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1228)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 297, 1185)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3161)
[M::mem_pestat] mean and std.dev: (538.05, 622.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4149)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681276 sequences (100000119 bp) in 1.830 CPU sec, 1.835 real sec...
[M::mem_process_seqs] Processed 682962 reads in 165.919 CPU sec, 5.282 real sec
[M::mem_process_seqs] Processed 681536 reads in 105.810 CPU sec, 3.347 real sec
sorting block 89, #reads = 1081467 mem = 536880733 peak = 1123155968
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 284120, 2, 13)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 348, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 934)
[M::mem_pestat] mean and std.dev: (338.80, 160.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1166)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 338, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 981)
[M::mem_pestat] mean and std.dev: (354.24, 170.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1236)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (342, 475, 475)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (76, 741)
[M::mem_pestat] mean and std.dev: (379.08, 131.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 904)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682260 sequences (100000267 bp) in 2.520 CPU sec, 2.640 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 283943, 2, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 290, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 586)
[M::mem_pestat] mean and std.dev: (267.74, 76.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 707)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 340, 477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 997)
[M::mem_pestat] mean and std.dev: (357.84, 173.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1257)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 266, 278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (89, 404)
[M::mem_pestat] mean and std.dev: (236.56, 48.01)
[M::mem_pestat] low and high boundaries for proper pairs: (26, 467)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681316 reads in 165.623 CPU sec, 5.271 real sec
[M::process] read 684192 sequences (100000010 bp) in 1.878 CPU sec, 1.886 real sec...
[M::mem_process_seqs] Processed 681276 reads in 107.280 CPU sec, 3.384 real sec
sorting block 90, #reads = 1081481 mem = 536877977 peak = 1123155968
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 284849, 2, 10)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 263, 275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (29, 439)
[M::mem_pestat] mean and std.dev: (232.22, 46.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 521)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 333, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 986)
[M::mem_pestat] mean and std.dev: (351.55, 171.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1244)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 402, 822)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2026)
[M::mem_pestat] mean and std.dev: (424.00, 272.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2628)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683082 sequences (100000061 bp) in 2.281 CPU sec, 2.367 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 286006, 1, 16)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 198, 533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1309)
[M::mem_pestat] mean and std.dev: (249.17, 163.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1697)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 317, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 956)
[M::mem_pestat] mean and std.dev: (339.24, 168.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1207)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 299, 385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 889)
[M::mem_pestat] mean and std.dev: (235.54, 99.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1141)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682842 sequences (100000097 bp) in 1.894 CPU sec, 1.898 real sec...
[M::mem_process_seqs] Processed 682260 reads in 167.585 CPU sec, 5.336 real sec
sorting block 91, #reads = 1080389 mem = 536879555 peak = 1123155968
[M::mem_process_seqs] Processed 684192 reads in 109.084 CPU sec, 3.449 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (11, 285452, 4, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 325, 611)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1479)
[M::mem_pestat] mean and std.dev: (346.36, 188.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1913)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 326, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 970)
[M::mem_pestat] mean and std.dev: (345.75, 169.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1224)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (321, 414, 591)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1131)
[M::mem_pestat] mean and std.dev: (369.00, 155.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1401)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 92, #reads = 1082815 mem = 536878641 peak = 1123155968
[M::process] read 682344 sequences (100000075 bp) in 2.326 CPU sec, 2.467 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 285127, 7, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 229, 603)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1519)
[M::mem_pestat] mean and std.dev: (419.89, 384.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1977)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 681396 sequences (100000187 bp) in 1.622 CPU sec, 1.630 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (210, 329, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 981)
[M::mem_pestat] mean and std.dev: (348.76, 170.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1238)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 288, 558)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1160)
[M::mem_pestat] mean and std.dev: (349.67, 208.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1461)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683082 reads in 171.128 CPU sec, 5.476 real sec
[M::mem_process_seqs] Processed 682842 reads in 112.573 CPU sec, 3.585 real sec
sorting block 93, #reads = 1081354 mem = 536880652 peak = 1123155968
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (18, 285361, 4, 14)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 354, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 896)
[M::mem_pestat] mean and std.dev: (310.07, 108.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1119)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 332, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 983)
[M::mem_pestat] mean and std.dev: (351.48, 171.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1240)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (266, 366, 480)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 908)
[M::mem_pestat] mean and std.dev: (312.92, 106.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1122)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681240 sequences (100000111 bp) in 2.793 CPU sec, 2.907 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (12, 284066, 1, 3)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 380, 562)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1264)
[M::mem_pestat] mean and std.dev: (348.36, 206.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1615)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 336, 476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 998)
[M::mem_pestat] mean and std.dev: (355.97, 173.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1259)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::process] read 682008 sequences (100000152 bp) in 1.945 CPU sec, 1.948 real sec...
[M::mem_process_seqs] Processed 682344 reads in 174.844 CPU sec, 5.555 real sec
[M::mem_process_seqs] Processed 681396 reads in 113.821 CPU sec, 3.601 real sec
sorting block 94, #reads = 1079851 mem = 536881539 peak = 1123155968
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 284667, 6, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (257, 409, 564)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1178)
[M::mem_pestat] mean and std.dev: (455.09, 269.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1532)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 338, 476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 996)
[M::mem_pestat] mean and std.dev: (357.47, 174.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1256)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 253, 502)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1182)
[M::mem_pestat] mean and std.dev: (289.96, 152.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1522)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682220 sequences (100000204 bp) in 2.647 CPU sec, 2.765 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (18, 285151, 4, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 185, 238)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (4, 394)
[M::mem_pestat] mean and std.dev: (196.56, 64.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 472)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 328, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 976)
[M::mem_pestat] mean and std.dev: (349.48, 171.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1231)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 214, 516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1264)
[M::mem_pestat] mean and std.dev: (289.90, 199.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1638)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682040 sequences (100000145 bp) in 1.940 CPU sec, 1.938 real sec...
[M::mem_process_seqs] Processed 681240 reads in 176.054 CPU sec, 5.608 real sec
[M::mem_process_seqs] Processed 682008 reads in 117.630 CPU sec, 3.712 real sec
sorting block 95, #reads = 1080646 mem = 536879721 peak = 1123155968
[M::process] read 681658 sequences (100000279 bp) in 2.917 CPU sec, 3.021 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (16, 285324, 3, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 253, 484)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1070)
[M::mem_pestat] mean and std.dev: (339.00, 200.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1363)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 330, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 989)
[M::mem_pestat] mean and std.dev: (352.47, 174.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1248)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 461, 478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1018)
[M::mem_pestat] mean and std.dev: (358.00, 156.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1288)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682252 sequences (100000090 bp) in 1.961 CPU sec, 1.967 real sec...
[M::mem_process_seqs] Processed 682040 reads in 98.637 CPU sec, 3.102 real sec
sorting block 96, #reads = 1078295 mem = 536879470 peak = 1123155968
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 284817, 1, 13)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 374, 602)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1486)
[M::mem_pestat] mean and std.dev: (422.83, 303.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1928)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 328, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 978)
[M::mem_pestat] mean and std.dev: (349.26, 171.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1234)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (104, 142, 283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 641)
[M::mem_pestat] mean and std.dev: (160.42, 84.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 820)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (16, 284834, 1, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 309, 511)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1149)
[M::mem_pestat] mean and std.dev: (334.69, 226.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1468)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 332, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 992)
[M::mem_pestat] mean and std.dev: (353.17, 174.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1252)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (276, 303, 769)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1755)
[M::mem_pestat] mean and std.dev: (442.64, 352.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2248)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682220 reads in 276.278 CPU sec, 8.772 real sec
[M::process] read 681900 sequences (100000131 bp) in 2.365 CPU sec, 2.375 real sec...
[M::mem_process_seqs] Processed 681658 reads in 132.786 CPU sec, 4.227 real sec
sorting block 97, #reads = 1078154 mem = 536876867 peak = 1123155968
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 284827, 0, 18)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 254, 508)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1218)
[M::mem_pestat] mean and std.dev: (326.20, 252.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1573)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 328, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 993)
[M::mem_pestat] mean and std.dev: (351.40, 174.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1254)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 242, 278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (71, 416)
[M::mem_pestat] mean and std.dev: (219.00, 39.11)
[M::mem_pestat] low and high boundaries for proper pairs: (2, 485)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682564 sequences (100000270 bp) in 2.553 CPU sec, 2.736 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (16, 285394, 3, 15)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 221, 252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (3, 418)
[M::mem_pestat] mean and std.dev: (199.43, 66.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 501)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 330, 474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1000)
[M::mem_pestat] mean and std.dev: (354.20, 176.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1263)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 190, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 954)
[M::mem_pestat] mean and std.dev: (246.77, 114.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1211)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682084 sequences (100000108 bp) in 1.949 CPU sec, 1.945 real sec...
[M::mem_process_seqs] Processed 682252 reads in 177.384 CPU sec, 5.653 real sec
sorting block 98, #reads = 1079665 mem = 536878585 peak = 1123155968
[M::mem_process_seqs] Processed 681900 reads in 115.665 CPU sec, 3.663 real sec
sorting block 99, #reads = 1078547 mem = 536878046 peak = 1123155968
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (12, 285357, 2, 20)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 342, 694)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1734)
[M::mem_pestat] mean and std.dev: (313.55, 207.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2254)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 323, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 979)
[M::mem_pestat] mean and std.dev: (348.20, 173.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1236)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 322, 394)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (284.47, 90.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 841)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 687238 sequences (100000094 bp) in 2.697 CPU sec, 2.827 real sec...
[M::process] read 685176 sequences (100000084 bp) in 1.714 CPU sec, 1.721 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 284599, 1, 18)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 226, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1067)
[M::mem_pestat] mean and std.dev: (266.00, 186.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1371)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 324, 464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 972)
[M::mem_pestat] mean and std.dev: (347.91, 172.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1226)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 281, 422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 864)
[M::mem_pestat] mean and std.dev: (308.83, 135.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1085)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682564 reads in 189.185 CPU sec, 6.022 real sec
[M::mem_process_seqs] Processed 682084 reads in 129.132 CPU sec, 4.105 real sec
sorting block 100, #reads = 1075680 mem = 536877897 peak = 1123155968
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (17, 286969, 1, 17)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (129, 409, 794)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2124)
[M::mem_pestat] mean and std.dev: (392.19, 289.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2789)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 299, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 938)
[M::mem_pestat] mean and std.dev: (326.71, 167.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1187)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 261, 1293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3551)
[M::mem_pestat] mean and std.dev: (581.29, 730.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4680)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683924 sequences (100000130 bp) in 2.421 CPU sec, 2.864 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (13, 286055, 9, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 379, 1225)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3145)
[M::mem_pestat] mean and std.dev: (523.31, 395.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4105)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 311, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 963)
[M::mem_pestat] mean and std.dev: (335.76, 168.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1218)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 387, 699)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1679)
[M::mem_pestat] mean and std.dev: (429.10, 248.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2169)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683156 sequences (100000240 bp) in 1.892 CPU sec, 1.931 real sec...
[M::mem_process_seqs] Processed 687238 reads in 192.937 CPU sec, 6.215 real sec
[M::mem_process_seqs] Processed 685176 reads in 124.718 CPU sec, 3.987 real sec
sorting block 101, #reads = 1073738 mem = 536876615 peak = 1123155968
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (18, 286061, 1, 8)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 251, 1756)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4942)
[M::mem_pestat] mean and std.dev: (692.00, 704.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6535)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 321, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 978)
[M::mem_pestat] mean and std.dev: (342.66, 169.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1236)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::process] read 682652 sequences (100000007 bp) in 2.846 CPU sec, 3.051 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 285413, 1, 20)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (123, 232, 549)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1401)
[M::mem_pestat] mean and std.dev: (397.09, 372.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1885)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 328, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 973)
[M::mem_pestat] mean and std.dev: (345.89, 168.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1228)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 171, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 707)
[M::mem_pestat] mean and std.dev: (178.50, 75.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 903)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681964 sequences (100000229 bp) in 1.762 CPU sec, 1.778 real sec...
[M::mem_process_seqs] Processed 683924 reads in 182.362 CPU sec, 5.842 real sec
[M::mem_process_seqs] Processed 683156 reads in 118.734 CPU sec, 3.784 real sec
sorting block 102, #reads = 1077070 mem = 536877698 peak = 1123155968
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (5, 285510, 3, 26)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 330, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 978)
[M::mem_pestat] mean and std.dev: (348.50, 168.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1234)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 226, 420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 888)
[M::mem_pestat] mean and std.dev: (230.86, 96.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1122)
[M::mem_pestat] skip orientation RR
[M::process] read 681810 sequences (100000200 bp) in 2.492 CPU sec, 3.065 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (18, 284978, 0, 15)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (118, 195, 225)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 439)
[M::mem_pestat] mean and std.dev: (177.67, 60.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 546)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 336, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 985)
[M::mem_pestat] mean and std.dev: (352.38, 169.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1242)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 337, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (271.00, 112.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 945)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682652 reads in 180.921 CPU sec, 5.826 real sec
[M::process] read 683122 sequences (100000116 bp) in 1.844 CPU sec, 1.856 real sec...
sorting block 103, #reads = 1078140 mem = 536878754 peak = 1123155968
[M::mem_process_seqs] Processed 681964 reads in 120.019 CPU sec, 3.823 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 284888, 2, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 218, 235)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 429)
[M::mem_pestat] mean and std.dev: (189.71, 54.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 526)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 338, 473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 991)
[M::mem_pestat] mean and std.dev: (353.33, 169.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1250)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (365, 583, 1344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3302)
[M::mem_pestat] mean and std.dev: (809.32, 698.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4281)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 104, #reads = 1076652 mem = 536875821 peak = 1123155968
[M::process] read 681770 sequences (100000081 bp) in 2.707 CPU sec, 3.090 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 285601, 1, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (246, 311, 403)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 717)
[M::mem_pestat] mean and std.dev: (293.14, 118.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 874)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 326, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 971)
[M::mem_pestat] mean and std.dev: (345.50, 167.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1225)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 324, 375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 771)
[M::mem_pestat] mean and std.dev: (271.70, 114.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 969)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681810 reads in 179.205 CPU sec, 5.767 real sec
[M::process] read 681530 sequences (100000077 bp) in 1.859 CPU sec, 1.898 real sec...
[M::mem_process_seqs] Processed 683122 reads in 118.080 CPU sec, 3.765 real sec
sorting block 105, #reads = 1078657 mem = 536880564 peak = 1123155968
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (18, 285068, 12, 17)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (121, 159, 223)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 427)
[M::mem_pestat] mean and std.dev: (156.88, 48.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 529)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 331, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 969)
[M::mem_pestat] mean and std.dev: (348.81, 167.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1221)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (396, 396, 1186)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2766)
[M::mem_pestat] mean and std.dev: (594.18, 432.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3556)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 469, 764)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1790)
[M::mem_pestat] mean and std.dev: (471.35, 242.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2303)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681568 sequences (100000291 bp) in 2.355 CPU sec, 2.739 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 284733, 4, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 339, 812)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2102)
[M::mem_pestat] mean and std.dev: (414.68, 405.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2747)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 334, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 968)
[M::mem_pestat] mean and std.dev: (350.52, 167.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1219)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 219, 534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1272)
[M::mem_pestat] mean and std.dev: (325.23, 213.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1641)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681770 reads in 179.539 CPU sec, 5.817 real sec
[M::process] read 681448 sequences (100000160 bp) in 2.231 CPU sec, 2.316 real sec...
[M::mem_process_seqs] Processed 681530 reads in 118.803 CPU sec, 3.806 real sec
sorting block 106, #reads = 1079475 mem = 536882197 peak = 1123155968
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 284467, 4, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 196, 244)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 428)
[M::mem_pestat] mean and std.dev: (204.22, 69.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 520)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 331, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 953)
[M::mem_pestat] mean and std.dev: (347.24, 164.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1199)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 388, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 921)
[M::mem_pestat] mean and std.dev: (355.11, 149.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1146)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680974 sequences (100000117 bp) in 2.452 CPU sec, 2.675 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (13, 284945, 1, 19)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (103, 164, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 712)
[M::mem_pestat] mean and std.dev: (202.69, 117.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 915)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 328, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 937)
[M::mem_pestat] mean and std.dev: (343.97, 161.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1178)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 187, 492)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1154)
[M::mem_pestat] mean and std.dev: (281.39, 166.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1485)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681154 sequences (100000155 bp) in 1.891 CPU sec, 1.919 real sec...
[M::mem_process_seqs] Processed 681568 reads in 185.431 CPU sec, 5.967 real sec
sorting block 107, #reads = 1078555 mem = 536876530 peak = 1123155968
[M::mem_process_seqs] Processed 681448 reads in 121.956 CPU sec, 3.903 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 284425, 3, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 228, 381)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 809)
[M::mem_pestat] mean and std.dev: (286.25, 165.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1023)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 329, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 938)
[M::mem_pestat] mean and std.dev: (345.86, 163.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1179)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (271, 397, 417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709)
[M::mem_pestat] mean and std.dev: (346.74, 107.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 855)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 108, #reads = 1077216 mem = 536878676 peak = 1123155968
[M::process] read 681010 sequences (100000242 bp) in 2.566 CPU sec, 2.851 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 284676, 0, 18)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 309, 540)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1286)
[M::mem_pestat] mean and std.dev: (347.30, 210.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1659)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 328, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 941)
[M::mem_pestat] mean and std.dev: (345.95, 164.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1183)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 271, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 561)
[M::mem_pestat] mean and std.dev: (251.35, 88.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 683)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680974 reads in 180.913 CPU sec, 5.842 real sec
[M::process] read 680934 sequences (100000166 bp) in 1.925 CPU sec, 1.953 real sec...
[M::mem_process_seqs] Processed 681154 reads in 117.223 CPU sec, 3.751 real sec
sorting block 109, #reads = 1078006 mem = 536877928 peak = 1123155968
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (10, 283848, 3, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (112, 149, 521)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1339)
[M::mem_pestat] mean and std.dev: (263.00, 207.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1748)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 328, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 938)
[M::mem_pestat] mean and std.dev: (345.38, 163.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1179)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 305, 464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 938)
[M::mem_pestat] mean and std.dev: (318.78, 138.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1175)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681440 sequences (100000113 bp) in 2.640 CPU sec, 2.882 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (14, 283822, 3, 17)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 262, 384)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 816)
[M::mem_pestat] mean and std.dev: (217.45, 84.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1032)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 327, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 934)
[M::mem_pestat] mean and std.dev: (344.51, 163.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1174)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 287, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 617)
[M::mem_pestat] mean and std.dev: (277.94, 73.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 749)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681100 sequences (100000100 bp) in 1.874 CPU sec, 1.880 real sec...
[M::mem_process_seqs] Processed 681010 reads in 178.136 CPU sec, 5.698 real sec
[M::mem_process_seqs] Processed 680934 reads in 115.943 CPU sec, 3.690 real sec
sorting block 110, #reads = 1079499 mem = 536877418 peak = 1123155968
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (16, 284416, 3, 20)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 342, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 905)
[M::mem_pestat] mean and std.dev: (308.47, 129.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1129)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 323, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 935)
[M::mem_pestat] mean and std.dev: (342.72, 163.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1176)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 345, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 853)
[M::mem_pestat] mean and std.dev: (315.11, 103.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1061)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680710 sequences (100000218 bp) in 2.425 CPU sec, 2.687 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 284532, 3, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 264, 416)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 816)
[M::mem_pestat] mean and std.dev: (322.21, 163.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1016)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 327, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 938)
[M::mem_pestat] mean and std.dev: (345.85, 165.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1179)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 224, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 704)
[M::mem_pestat] mean and std.dev: (242.55, 123.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 887)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680728 sequences (100000069 bp) in 1.915 CPU sec, 1.932 real sec...
[M::mem_process_seqs] Processed 681440 reads in 174.933 CPU sec, 5.600 real sec
[M::mem_process_seqs] Processed 681100 reads in 114.598 CPU sec, 3.637 real sec
sorting block 111, #reads = 1079437 mem = 536879772 peak = 1123155968
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (16, 283960, 3, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 242, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 614)
[M::mem_pestat] mean and std.dev: (239.19, 72.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 756)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 329, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 936)
[M::mem_pestat] mean and std.dev: (346.76, 164.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1176)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 465, 841)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2057)
[M::mem_pestat] mean and std.dev: (432.80, 235.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2665)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680810 sequences (100000139 bp) in 2.683 CPU sec, 2.968 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 283996, 1, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 262, 394)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 900)
[M::mem_pestat] mean and std.dev: (296.08, 181.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1153)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 329, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 942)
[M::mem_pestat] mean and std.dev: (347.56, 165.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1184)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 311, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 607)
[M::mem_pestat] mean and std.dev: (280.60, 85.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 733)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680710 reads in 174.589 CPU sec, 5.624 real sec
[M::process] read 680650 sequences (100000096 bp) in 2.048 CPU sec, 2.118 real sec...
sorting block 112, #reads = 1080475 mem = 536878149 peak = 1123155968
[M::mem_process_seqs] Processed 680728 reads in 114.509 CPU sec, 3.652 real sec
[M::process] read 185558 sequences (27219921 bp) in 0.907 CPU sec, 1.006 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 284844, 5, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 292, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 833)
[M::mem_pestat] mean and std.dev: (250.91, 132.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1065)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 330, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 954)
[M::mem_pestat] mean and std.dev: (349.68, 167.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1200)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 285, 533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1133)
[M::mem_pestat] mean and std.dev: (340.16, 194.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1433)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 113, #reads = 1080380 mem = 536877751 peak = 1123155968
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (10, 284898, 8, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 247, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 627)
[M::mem_pestat] mean and std.dev: (247.90, 103.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 791)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 332, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 955)
[M::mem_pestat] mean and std.dev: (351.13, 168.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1201)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 249, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 769)
[M::mem_pestat] mean and std.dev: (235.64, 108.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 975)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680810 reads in 170.530 CPU sec, 5.563 real sec
[M::mem_process_seqs] Processed 680650 reads in 112.281 CPU sec, 3.642 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (11, 77623, 2, 6)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 379, 390)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 724)
[M::mem_pestat] mean and std.dev: (295.64, 100.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 891)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 324, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 942)
[M::mem_pestat] mean and std.dev: (343.32, 165.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1186)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::mem_process_seqs] Processed 185558 reads in 28.576 CPU sec, 0.977 real sec
sorting block 114, #reads = 1080891 mem = 536877869 peak = 1123155968
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 124251978
overall: 69841891328 mem 17858.440 user 495.740 sys 611.213 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1136_5L2-T1-TDNA-1_A23MHWWLT4_1.L001\tPU:L001\tSM:1136_5L2-T1-TDNA-1_A23MHWWLT4_1\tLB:1136_5L2-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1136_5L2-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1136_5L2-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 611.249 sec; CPU: 18354.184 sec
sorting block 115, #reads = 583777 mem = 290689298 peak = 1123155968
uniq header count 1
merging 116 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31 max 192
algo: util-sort
license: sentieon:util=1
output file size: 6815179571
output reads: 124793187
bam_mem_sort: 116 calls 63.933 user 1.400 sys 66.188 real
bam_write: 116 calls 42.237 user 2.799 sys 61.146 real
execute: 1 calls 37.317 user 3.000 sys 664.478 real
merge_files: 1 calls 37.293 user 2.979 sys 52.737 real
parse_chunk: 1849 calls 77.869 user 21.079 sys 106.957 real
read_chunk: 4985 calls 45.944 user 34.775 sys 554.630 real
sort_block: 1 calls 28.020 user 33.417 sys 527.557 real
write_chunk: 3134 calls 36.730 user 2.681 sys 51.456 real
overall: 3088580608 mem 1928.434 user 85.558 sys 664.499 real
ls: cannot access '*.cram': No such file or directory