This software is licensed to bgold@natera.com by Sentieon Inc.
cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1136_7GC-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 1588.439 CPU sec, 60.024 real sec
[M::process] read 709340 sequences (100000212 bp) in 1.178 CPU sec, 1.185 real sec...
[M::process] read 709008 sequences (100000268 bp) in 1.400 CPU sec, 1.396 real sec...
[M::process] read 708110 sequences (100000085 bp) in 1.400 CPU sec, 1.398 real sec...
[M::process] read 708194 sequences (100000120 bp) in 1.438 CPU sec, 1.447 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 288983, 31, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 333, 865)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2197)
[M::mem_pestat] mean and std.dev: (532.53, 535.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2863)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 217, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 654)
[M::mem_pestat] mean and std.dev: (240.95, 119.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 823)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (483, 823, 1290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2904)
[M::mem_pestat] mean and std.dev: (908.54, 692.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3711)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (258, 457, 1141)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2907)
[M::mem_pestat] mean and std.dev: (776.39, 707.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3790)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 709008 reads in 95.426 CPU sec, 3.027 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 288812, 22, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 566, 1512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4152)
[M::mem_pestat] mean and std.dev: (867.48, 844.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5472)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 216, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 645)
[M::mem_pestat] mean and std.dev: (239.55, 118.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 811)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (424, 1079, 3354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9214)
[M::mem_pestat] mean and std.dev: (2069.05, 2348.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12144)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 323, 671)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1595)
[M::mem_pestat] mean and std.dev: (428.44, 295.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2057)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707368 sequences (100000217 bp) in 1.624 CPU sec, 1.632 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 289022, 31, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 278, 687)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1777)
[M::mem_pestat] mean and std.dev: (464.64, 468.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2338)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 219, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 658)
[M::mem_pestat] mean and std.dev: (242.64, 120.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 828)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (445, 716, 2554)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6772)
[M::mem_pestat] mean and std.dev: (1653.52, 1763.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8881)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (274, 424, 1256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3220)
[M::mem_pestat] mean and std.dev: (706.17, 717.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4202)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 709340 reads in 260.793 CPU sec, 8.235 real sec
sorting block 0, #reads = 1087057 mem = 536877560 peak = 639721472
[M::mem_process_seqs] Processed 708110 reads in 132.730 CPU sec, 4.243 real sec
[M::process] read 707280 sequences (100000142 bp) in 2.298 CPU sec, 2.339 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 288664, 40, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 293, 796)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2052)
[M::mem_pestat] mean and std.dev: (420.23, 423.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2680)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 219, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 655)
[M::mem_pestat] mean and std.dev: (242.51, 120.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 824)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (355, 855, 1397)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3481)
[M::mem_pestat] mean and std.dev: (821.97, 617.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4523)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 364, 880)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2232)
[M::mem_pestat] mean and std.dev: (481.59, 410.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2908)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706764 sequences (100000166 bp) in 1.487 CPU sec, 1.490 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 289176, 27, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 429, 1070)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2756)
[M::mem_pestat] mean and std.dev: (615.98, 556.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3599)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 220, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 659)
[M::mem_pestat] mean and std.dev: (243.63, 120.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 829)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (393, 565, 1233)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2913)
[M::mem_pestat] mean and std.dev: (793.76, 763.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3846)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 381, 859)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2207)
[M::mem_pestat] mean and std.dev: (457.30, 410.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2881)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 708194 reads in 155.905 CPU sec, 4.928 real sec
sorting block 1, #reads = 1088634 mem = 536884140 peak = 877223936
[M::mem_process_seqs] Processed 707368 reads in 175.499 CPU sec, 5.573 real sec
sorting block 2, #reads = 1088228 mem = 536879736 peak = 929136640
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 288730, 27, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 299, 777)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1945)
[M::mem_pestat] mean and std.dev: (428.80, 381.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2529)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 221, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 662)
[M::mem_pestat] mean and std.dev: (244.25, 120.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 833)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (390, 696, 2368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6324)
[M::mem_pestat] mean and std.dev: (1140.54, 1179.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8302)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (264, 352, 690)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1542)
[M::mem_pestat] mean and std.dev: (435.67, 295.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1968)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706454 sequences (100000011 bp) in 2.388 CPU sec, 2.449 real sec...
[M::process] read 705354 sequences (100000176 bp) in 1.510 CPU sec, 1.506 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (89, 288170, 35, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 433, 1124)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2924)
[M::mem_pestat] mean and std.dev: (605.42, 514.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3824)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 222, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 663)
[M::mem_pestat] mean and std.dev: (245.22, 121.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (318, 531, 1070)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2574)
[M::mem_pestat] mean and std.dev: (660.91, 498.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3326)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 307, 605)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1397)
[M::mem_pestat] mean and std.dev: (386.66, 275.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1793)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707280 reads in 159.772 CPU sec, 5.056 real sec
[M::mem_process_seqs] Processed 706764 reads in 108.890 CPU sec, 3.479 real sec
sorting block 3, #reads = 1087317 mem = 536879054 peak = 929136640
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 288192, 46, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 367, 999)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2551)
[M::mem_pestat] mean and std.dev: (539.96, 481.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3327)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 223, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 672)
[M::mem_pestat] mean and std.dev: (247.24, 123.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 846)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (466, 883, 1178)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2602)
[M::mem_pestat] mean and std.dev: (790.00, 469.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3314)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (335, 616, 1219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2987)
[M::mem_pestat] mean and std.dev: (741.36, 638.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3871)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704920 sequences (100000229 bp) in 2.817 CPU sec, 2.912 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 287464, 39, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 411, 1102)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2926)
[M::mem_pestat] mean and std.dev: (613.29, 620.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3838)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 225, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (248.91, 123.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 848)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 774, 1638)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4512)
[M::mem_pestat] mean and std.dev: (722.67, 783.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5949)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (141, 221, 712)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1854)
[M::mem_pestat] mean and std.dev: (350.97, 398.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2425)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706454 reads in 172.622 CPU sec, 5.449 real sec
[M::process] read 705024 sequences (100000139 bp) in 2.260 CPU sec, 2.254 real sec...
sorting block 4, #reads = 1086381 mem = 536880611 peak = 929136640
[M::mem_process_seqs] Processed 705354 reads in 119.102 CPU sec, 3.758 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 287735, 43, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (329, 483, 1068)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2546)
[M::mem_pestat] mean and std.dev: (648.98, 446.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3285)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 226, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (250.24, 124.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 856)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (331, 862, 1910)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5068)
[M::mem_pestat] mean and std.dev: (1099.63, 1030.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6647)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (276, 419, 1144)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2880)
[M::mem_pestat] mean and std.dev: (799.02, 768.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3875)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704842 sequences (100000166 bp) in 2.388 CPU sec, 2.510 real sec...
[M::process] read 704658 sequences (100000224 bp) in 1.980 CPU sec, 1.978 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 287641, 39, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 353, 1311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3541)
[M::mem_pestat] mean and std.dev: (735.26, 814.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4656)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 227, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (251.03, 125.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 860)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (561, 684, 937)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1689)
[M::mem_pestat] mean and std.dev: (621.47, 358.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2065)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 273, 602)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1454)
[M::mem_pestat] mean and std.dev: (385.67, 306.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1880)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704920 reads in 182.144 CPU sec, 5.801 real sec
sorting block 5, #reads = 1086538 mem = 536879749 peak = 929136640
[M::mem_process_seqs] Processed 705024 reads in 130.907 CPU sec, 4.195 real sec
sorting block 6, #reads = 1085802 mem = 536877880 peak = 929136640
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 287720, 48, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (302, 385, 719)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1553)
[M::mem_pestat] mean and std.dev: (467.38, 331.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1970)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 228, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (252.26, 126.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 869)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (298, 720, 2421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6667)
[M::mem_pestat] mean and std.dev: (1330.02, 1508.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8790)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 434, 1169)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3055)
[M::mem_pestat] mean and std.dev: (789.72, 743.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3998)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704198 sequences (100000230 bp) in 2.985 CPU sec, 3.146 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 287672, 31, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 362, 1167)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3165)
[M::mem_pestat] mean and std.dev: (683.48, 731.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4164)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 228, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (252.56, 126.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 869)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (390, 473, 1050)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2370)
[M::mem_pestat] mean and std.dev: (644.50, 508.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3030)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (278, 325, 989)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2411)
[M::mem_pestat] mean and std.dev: (537.68, 495.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3122)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703510 sequences (100000143 bp) in 2.281 CPU sec, 2.285 real sec...
[M::mem_process_seqs] Processed 704842 reads in 188.880 CPU sec, 6.043 real sec
[M::mem_process_seqs] Processed 704658 reads in 132.027 CPU sec, 4.227 real sec
sorting block 7, #reads = 1087185 mem = 536879386 peak = 929136640
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 287256, 41, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 334, 751)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1871)
[M::mem_pestat] mean and std.dev: (408.94, 313.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2431)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (252.22, 125.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 862)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (394, 712, 1160)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2692)
[M::mem_pestat] mean and std.dev: (771.95, 523.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3458)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 303, 603)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1381)
[M::mem_pestat] mean and std.dev: (346.36, 233.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1770)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703868 sequences (100000197 bp) in 2.789 CPU sec, 2.889 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 287516, 25, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 337, 810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2002)
[M::mem_pestat] mean and std.dev: (443.34, 387.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2598)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (253.08, 126.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (493, 794, 1428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3298)
[M::mem_pestat] mean and std.dev: (809.55, 597.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4233)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 266, 774)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1960)
[M::mem_pestat] mean and std.dev: (454.94, 466.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2553)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703556 sequences (100000174 bp) in 2.213 CPU sec, 2.220 real sec...
[M::mem_process_seqs] Processed 704198 reads in 190.239 CPU sec, 6.140 real sec
[M::mem_process_seqs] Processed 703510 reads in 132.682 CPU sec, 4.310 real sec
sorting block 8, #reads = 1086283 mem = 536878423 peak = 929136640
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 287080, 28, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 248, 760)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1878)
[M::mem_pestat] mean and std.dev: (382.31, 341.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2437)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (251.95, 125.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 964, 1724)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4742)
[M::mem_pestat] mean and std.dev: (1064.93, 953.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6251)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 475, 1959)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5439)
[M::mem_pestat] mean and std.dev: (1013.56, 1161.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7179)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703298 sequences (100000003 bp) in 2.991 CPU sec, 3.183 real sec...
[M::process] read 703618 sequences (100000054 bp) in 2.161 CPU sec, 2.176 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 287397, 20, 98)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (253, 389, 819)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1951)
[M::mem_pestat] mean and std.dev: (422.98, 319.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2517)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (251.93, 125.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 741, 1789)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5047)
[M::mem_pestat] mean and std.dev: (778.56, 799.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6676)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 316, 1370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3664)
[M::mem_pestat] mean and std.dev: (732.93, 778.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4811)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703868 reads in 198.130 CPU sec, 6.292 real sec
sorting block 9, #reads = 1085739 mem = 536879254 peak = 929136640
[M::mem_process_seqs] Processed 703556 reads in 136.182 CPU sec, 4.334 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 287326, 50, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 325, 1075)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2803)
[M::mem_pestat] mean and std.dev: (535.04, 585.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3667)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (252.16, 125.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 936, 2388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6864)
[M::mem_pestat] mean and std.dev: (1368.63, 1384.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9102)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 349, 534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1204)
[M::mem_pestat] mean and std.dev: (379.98, 256.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1539)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 10, #reads = 1085935 mem = 536883705 peak = 941760512
[M::process] read 703742 sequences (100000087 bp) in 2.954 CPU sec, 3.158 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 287009, 27, 103)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 373, 887)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2247)
[M::mem_pestat] mean and std.dev: (465.47, 348.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2927)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (251.59, 124.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (689, 1168, 2455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5987)
[M::mem_pestat] mean and std.dev: (1172.52, 964.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7753)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 380, 1118)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2964)
[M::mem_pestat] mean and std.dev: (553.55, 560.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3887)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703736 sequences (100000195 bp) in 2.305 CPU sec, 2.304 real sec...
[M::mem_process_seqs] Processed 703298 reads in 199.660 CPU sec, 6.355 real sec
[M::mem_process_seqs] Processed 703618 reads in 137.601 CPU sec, 4.364 real sec
sorting block 11, #reads = 1085661 mem = 536879837 peak = 941760512
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 287401, 48, 94)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 414, 1047)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2761)
[M::mem_pestat] mean and std.dev: (619.00, 635.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3618)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 676)
[M::mem_pestat] mean and std.dev: (250.57, 123.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 850)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 893, 1795)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5091)
[M::mem_pestat] mean and std.dev: (1069.71, 1140.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6739)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 342, 997)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2553)
[M::mem_pestat] mean and std.dev: (550.56, 554.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3331)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703706 sequences (100000005 bp) in 3.248 CPU sec, 3.399 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 287568, 33, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 299, 1355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3633)
[M::mem_pestat] mean and std.dev: (688.97, 741.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4772)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (251.23, 124.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (391, 1084, 2665)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7213)
[M::mem_pestat] mean and std.dev: (1434.82, 1246.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9487)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (319, 682, 2071)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5575)
[M::mem_pestat] mean and std.dev: (1073.46, 1120.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7327)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703558 sequences (100000078 bp) in 2.375 CPU sec, 2.378 real sec...
[M::mem_process_seqs] Processed 703742 reads in 200.580 CPU sec, 6.386 real sec
[M::mem_process_seqs] Processed 703736 reads in 139.085 CPU sec, 4.408 real sec
sorting block 12, #reads = 1085708 mem = 536879827 peak = 941760512
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 287516, 60, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 474, 1089)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2875)
[M::mem_pestat] mean and std.dev: (612.93, 561.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3768)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 676)
[M::mem_pestat] mean and std.dev: (250.66, 124.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 850)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (109, 864, 1216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3430)
[M::mem_pestat] mean and std.dev: (776.61, 708.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4537)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 318, 1717)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4721)
[M::mem_pestat] mean and std.dev: (684.03, 856.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6223)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703296 sequences (100000111 bp) in 2.813 CPU sec, 2.917 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 287246, 43, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 287, 672)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1742)
[M::mem_pestat] mean and std.dev: (442.67, 419.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2277)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (251.52, 124.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 570, 1567)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4245)
[M::mem_pestat] mean and std.dev: (929.43, 1012.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5584)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 343, 1005)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2589)
[M::mem_pestat] mean and std.dev: (542.21, 509.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3381)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702654 sequences (100000188 bp) in 2.330 CPU sec, 2.335 real sec...
[M::mem_process_seqs] Processed 703706 reads in 198.168 CPU sec, 6.300 real sec
sorting block 13, #reads = 1086022 mem = 536877796 peak = 941760512
[M::mem_process_seqs] Processed 703558 reads in 137.263 CPU sec, 4.360 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 286906, 29, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 395, 2026)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5566)
[M::mem_pestat] mean and std.dev: (922.37, 1126.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7336)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 229, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (251.97, 124.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 855)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (290, 529, 1643)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4349)
[M::mem_pestat] mean and std.dev: (1074.28, 1057.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5702)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 344, 855)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2191)
[M::mem_pestat] mean and std.dev: (474.29, 389.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2859)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 14, #reads = 1086364 mem = 536880725 peak = 941760512
[M::process] read 702860 sequences (100000291 bp) in 3.278 CPU sec, 3.372 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 286172, 26, 81)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 252, 485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1173)
[M::mem_pestat] mean and std.dev: (273.70, 185.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1517)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 230, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (253.54, 125.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 859)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 662, 742)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1918)
[M::mem_pestat] mean and std.dev: (482.14, 298.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2506)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 361, 1079)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2829)
[M::mem_pestat] mean and std.dev: (536.45, 485.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3704)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701978 sequences (100000106 bp) in 2.219 CPU sec, 2.219 real sec...
[M::mem_process_seqs] Processed 703296 reads in 196.977 CPU sec, 6.246 real sec
[M::mem_process_seqs] Processed 702654 reads in 136.987 CPU sec, 4.355 real sec
sorting block 15, #reads = 1086362 mem = 536878099 peak = 941760512
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 287106, 29, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 284, 589)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1433)
[M::mem_pestat] mean and std.dev: (332.78, 275.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1855)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 230, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 686)
[M::mem_pestat] mean and std.dev: (253.46, 125.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 863)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 532, 1985)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5541)
[M::mem_pestat] mean and std.dev: (1117.28, 1166.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7319)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 281, 670)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1660)
[M::mem_pestat] mean and std.dev: (405.54, 353.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2155)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701398 sequences (100000144 bp) in 2.795 CPU sec, 2.857 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (79, 286304, 20, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 231, 481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1117)
[M::mem_pestat] mean and std.dev: (286.58, 199.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1435)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 232, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (254.98, 125.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (386, 664, 1087)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2489)
[M::mem_pestat] mean and std.dev: (634.94, 400.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3190)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 487, 1249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3301)
[M::mem_pestat] mean and std.dev: (670.35, 586.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4327)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701256 sequences (100000298 bp) in 2.240 CPU sec, 2.241 real sec...
[M::mem_process_seqs] Processed 702860 reads in 183.263 CPU sec, 5.800 real sec
[M::mem_process_seqs] Processed 701978 reads in 125.282 CPU sec, 3.958 real sec
sorting block 16, #reads = 1085387 mem = 536879309 peak = 941760512
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 285970, 30, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 315, 718)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1776)
[M::mem_pestat] mean and std.dev: (448.71, 436.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2305)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 233, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (255.84, 125.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 869)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (540, 1047, 2178)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5454)
[M::mem_pestat] mean and std.dev: (1412.70, 1177.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7092)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 402, 755)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1837)
[M::mem_pestat] mean and std.dev: (457.58, 313.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2378)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701696 sequences (100000197 bp) in 2.903 CPU sec, 3.002 real sec...
[M::process] read 700882 sequences (100000282 bp) in 1.810 CPU sec, 1.812 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 285768, 44, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 271, 619)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1551)
[M::mem_pestat] mean and std.dev: (319.03, 246.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2017)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 233, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 694)
[M::mem_pestat] mean and std.dev: (256.29, 125.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 873)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (414, 514, 1021)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2235)
[M::mem_pestat] mean and std.dev: (646.30, 534.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2842)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 398, 1276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3408)
[M::mem_pestat] mean and std.dev: (798.82, 875.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4474)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701398 reads in 177.111 CPU sec, 5.603 real sec
sorting block 17, #reads = 1085410 mem = 536880892 peak = 941760512
[M::mem_process_seqs] Processed 701256 reads in 119.009 CPU sec, 3.776 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 286252, 33, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 339, 861)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2179)
[M::mem_pestat] mean and std.dev: (484.90, 440.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2838)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 233, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 694)
[M::mem_pestat] mean and std.dev: (256.30, 126.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 873)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 513, 1041)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2643)
[M::mem_pestat] mean and std.dev: (600.97, 515.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3444)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 374, 1971)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5513)
[M::mem_pestat] mean and std.dev: (1104.31, 1231.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7284)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700912 sequences (100000228 bp) in 3.024 CPU sec, 3.243 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 286133, 34, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 257, 540)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1302)
[M::mem_pestat] mean and std.dev: (319.22, 227.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1683)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701)
[M::mem_pestat] mean and std.dev: (258.21, 127.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 882)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (394, 1151, 1541)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3835)
[M::mem_pestat] mean and std.dev: (1183.84, 894.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4982)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 329, 851)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2139)
[M::mem_pestat] mean and std.dev: (505.61, 462.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2783)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701696 reads in 172.046 CPU sec, 5.442 real sec
sorting block 18, #reads = 1083563 mem = 536882599 peak = 941760512
[M::process] read 700772 sequences (100000186 bp) in 2.452 CPU sec, 2.468 real sec...
[M::mem_process_seqs] Processed 700882 reads in 117.660 CPU sec, 3.711 real sec
sorting block 19, #reads = 1084078 mem = 536886128 peak = 997609472
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 285915, 35, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 434, 1076)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2846)
[M::mem_pestat] mean and std.dev: (594.55, 543.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3731)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 704)
[M::mem_pestat] mean and std.dev: (258.75, 127.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 886)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (407, 514, 1154)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2648)
[M::mem_pestat] mean and std.dev: (672.20, 622.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3395)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 281, 763)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1871)
[M::mem_pestat] mean and std.dev: (368.59, 329.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2425)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700446 sequences (100000099 bp) in 2.971 CPU sec, 3.025 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 286101, 39, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 330, 1106)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2934)
[M::mem_pestat] mean and std.dev: (585.23, 556.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3848)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 236, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 710)
[M::mem_pestat] mean and std.dev: (259.80, 128.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 894)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 898, 1970)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5530)
[M::mem_pestat] mean and std.dev: (1052.83, 1062.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7310)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 346, 1899)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5217)
[M::mem_pestat] mean and std.dev: (972.05, 1170.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6876)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700120 sequences (100000066 bp) in 1.940 CPU sec, 1.933 real sec...
[M::mem_process_seqs] Processed 700912 reads in 168.519 CPU sec, 5.327 real sec
[M::mem_process_seqs] Processed 700772 reads in 115.387 CPU sec, 3.641 real sec
sorting block 20, #reads = 1084501 mem = 536884328 peak = 997609472
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 285642, 31, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 263, 604)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1434)
[M::mem_pestat] mean and std.dev: (340.73, 252.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1849)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 236, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 705)
[M::mem_pestat] mean and std.dev: (259.99, 128.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 887)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (398, 792, 1579)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3941)
[M::mem_pestat] mean and std.dev: (974.69, 839.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5122)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 404, 904)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2308)
[M::mem_pestat] mean and std.dev: (534.03, 431.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3010)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708216 sequences (100000132 bp) in 2.303 CPU sec, 2.365 real sec...
[M::process] read 709730 sequences (100000226 bp) in 1.710 CPU sec, 1.715 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 286174, 24, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 363, 677)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1665)
[M::mem_pestat] mean and std.dev: (374.44, 259.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2159)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 237, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 711)
[M::mem_pestat] mean and std.dev: (260.82, 128.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 895)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 681, 1248)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3352)
[M::mem_pestat] mean and std.dev: (829.65, 811.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4404)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 469, 1503)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4065)
[M::mem_pestat] mean and std.dev: (773.93, 805.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5346)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700446 reads in 165.123 CPU sec, 5.241 real sec
[M::mem_process_seqs] Processed 700120 reads in 115.653 CPU sec, 3.688 real sec
sorting block 21, #reads = 1083173 mem = 536880030 peak = 997609472
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 288792, 28, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 555, 855)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2115)
[M::mem_pestat] mean and std.dev: (548.26, 446.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2745)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 220, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (243.90, 122.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 836)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 554, 988)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2490)
[M::mem_pestat] mean and std.dev: (623.59, 540.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3241)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 309, 726)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1714)
[M::mem_pestat] mean and std.dev: (413.02, 325.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2208)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708984 sequences (100000264 bp) in 2.423 CPU sec, 2.519 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 289202, 41, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 467, 1059)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2813)
[M::mem_pestat] mean and std.dev: (629.24, 616.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3690)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 217, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 662)
[M::mem_pestat] mean and std.dev: (242.10, 122.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (310, 1373, 3866)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10978)
[M::mem_pestat] mean and std.dev: (1777.80, 1688.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14534)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 344, 2291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6509)
[M::mem_pestat] mean and std.dev: (1303.16, 1586.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8618)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708708 sequences (100000144 bp) in 2.110 CPU sec, 2.116 real sec...
[M::mem_process_seqs] Processed 708216 reads in 176.693 CPU sec, 5.604 real sec
sorting block 22, #reads = 1083923 mem = 536877607 peak = 997609472
[M::mem_process_seqs] Processed 709730 reads in 117.473 CPU sec, 3.722 real sec
sorting block 23, #reads = 1091020 mem = 536880533 peak = 997609472
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 289392, 32, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 381, 680)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1702)
[M::mem_pestat] mean and std.dev: (424.96, 303.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2213)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 218, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 663)
[M::mem_pestat] mean and std.dev: (242.73, 122.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 835)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 226, 590)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1430)
[M::mem_pestat] mean and std.dev: (267.04, 183.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1850)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 284, 719)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1801)
[M::mem_pestat] mean and std.dev: (436.31, 379.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2342)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708520 sequences (100000210 bp) in 2.785 CPU sec, 2.859 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 289165, 32, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 302, 1236)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3400)
[M::mem_pestat] mean and std.dev: (702.26, 824.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4482)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 219, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (243.78, 122.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 836)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (455, 817, 1886)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4748)
[M::mem_pestat] mean and std.dev: (1005.40, 1001.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6179)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 260, 747)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1921)
[M::mem_pestat] mean and std.dev: (430.43, 423.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2508)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 708984 reads in 170.530 CPU sec, 5.378 real sec
[M::process] read 707990 sequences (100000126 bp) in 2.320 CPU sec, 2.316 real sec...
[M::mem_process_seqs] Processed 708708 reads in 117.732 CPU sec, 3.716 real sec
sorting block 24, #reads = 1089699 mem = 536877956 peak = 997609472
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 289031, 21, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (254, 433, 1268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3296)
[M::mem_pestat] mean and std.dev: (704.16, 768.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4310)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 219, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (243.74, 121.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 836)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (370, 1088, 2114)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5602)
[M::mem_pestat] mean and std.dev: (1419.62, 1254.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7346)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 366, 1409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3863)
[M::mem_pestat] mean and std.dev: (741.19, 850.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5090)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707508 sequences (100000033 bp) in 2.680 CPU sec, 2.767 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 288859, 46, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 314, 575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1409)
[M::mem_pestat] mean and std.dev: (339.12, 246.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1826)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 220, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (245.27, 123.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 845)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (530, 832, 2026)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5018)
[M::mem_pestat] mean and std.dev: (1183.40, 936.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6514)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 476, 867)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2217)
[M::mem_pestat] mean and std.dev: (525.28, 494.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2892)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707048 sequences (100000112 bp) in 1.970 CPU sec, 1.963 real sec...
[M::mem_process_seqs] Processed 708520 reads in 178.886 CPU sec, 5.676 real sec
[M::mem_process_seqs] Processed 707990 reads in 121.872 CPU sec, 3.865 real sec
sorting block 25, #reads = 1090002 mem = 536884946 peak = 997609472
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 288492, 29, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 288, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 979)
[M::mem_pestat] mean and std.dev: (295.18, 186.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1251)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 221, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (245.74, 123.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 845)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (385, 1043, 1632)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4126)
[M::mem_pestat] mean and std.dev: (1012.74, 654.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5373)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 363, 2435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6799)
[M::mem_pestat] mean and std.dev: (1204.53, 1417.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8981)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706858 sequences (100000284 bp) in 2.817 CPU sec, 2.882 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 288684, 31, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 373, 1283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3435)
[M::mem_pestat] mean and std.dev: (691.35, 716.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4511)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 222, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 672)
[M::mem_pestat] mean and std.dev: (246.78, 123.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 846)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (469, 1432, 2116)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5410)
[M::mem_pestat] mean and std.dev: (1415.03, 1032.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7057)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 334, 1010)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2586)
[M::mem_pestat] mean and std.dev: (519.54, 463.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3374)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707508 reads in 173.463 CPU sec, 5.482 real sec
[M::process] read 706020 sequences (100000088 bp) in 2.346 CPU sec, 2.350 real sec...
sorting block 26, #reads = 1089346 mem = 536880794 peak = 997609472
[M::mem_process_seqs] Processed 707048 reads in 118.411 CPU sec, 3.731 real sec
sorting block 27, #reads = 1088930 mem = 536876822 peak = 997609472
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 288253, 30, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 297, 1225)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3299)
[M::mem_pestat] mean and std.dev: (652.98, 680.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4336)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 223, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 678)
[M::mem_pestat] mean and std.dev: (248.27, 125.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (313, 896, 1215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3019)
[M::mem_pestat] mean and std.dev: (897.40, 591.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3921)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 293, 1128)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3030)
[M::mem_pestat] mean and std.dev: (633.81, 743.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3981)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705690 sequences (100000024 bp) in 3.082 CPU sec, 3.148 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (86, 287617, 28, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 438, 1022)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2582)
[M::mem_pestat] mean and std.dev: (605.11, 570.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3362)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 225, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (250.17, 126.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 863)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 406, 729)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1909)
[M::mem_pestat] mean and std.dev: (481.89, 429.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2499)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 412, 863)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2081)
[M::mem_pestat] mean and std.dev: (459.78, 357.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2690)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706858 reads in 178.034 CPU sec, 5.623 real sec
[M::process] read 705370 sequences (100000184 bp) in 2.369 CPU sec, 2.361 real sec...
[M::mem_process_seqs] Processed 706020 reads in 125.012 CPU sec, 3.944 real sec
sorting block 28, #reads = 1089351 mem = 536878154 peak = 997609472
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 287825, 32, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 483, 1547)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4325)
[M::mem_pestat] mean and std.dev: (839.80, 836.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5714)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 225, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (251.22, 126.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (293, 474, 1235)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3119)
[M::mem_pestat] mean and std.dev: (659.90, 564.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4061)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 467, 1290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3402)
[M::mem_pestat] mean and std.dev: (650.00, 605.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4458)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705162 sequences (100000069 bp) in 2.874 CPU sec, 2.973 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 287803, 42, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 345, 802)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2070)
[M::mem_pestat] mean and std.dev: (452.74, 377.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2704)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 226, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (252.30, 127.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 872)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 741, 1282)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3504)
[M::mem_pestat] mean and std.dev: (717.26, 545.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4615)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 315, 738)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1756)
[M::mem_pestat] mean and std.dev: (436.34, 324.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2265)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705204 sequences (100000127 bp) in 2.356 CPU sec, 2.361 real sec...
[M::mem_process_seqs] Processed 705690 reads in 187.658 CPU sec, 5.951 real sec
[M::mem_process_seqs] Processed 705370 reads in 134.578 CPU sec, 4.277 real sec
sorting block 29, #reads = 1088649 mem = 536878663 peak = 997609472
[M::process] read 704956 sequences (100000264 bp) in 3.137 CPU sec, 3.226 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (91, 287482, 21, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 351, 623)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1575)
[M::mem_pestat] mean and std.dev: (418.62, 340.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2051)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 227, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (252.51, 127.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 876)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 450, 1035)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2693)
[M::mem_pestat] mean and std.dev: (563.65, 399.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3522)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 279, 948)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2470)
[M::mem_pestat] mean and std.dev: (530.76, 510.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3231)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704620 sequences (100000219 bp) in 2.294 CPU sec, 2.303 real sec...
[M::mem_process_seqs] Processed 705204 reads in 113.149 CPU sec, 3.561 real sec
sorting block 30, #reads = 1088553 mem = 536885504 peak = 997609472
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 287632, 28, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 370, 737)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1743)
[M::mem_pestat] mean and std.dev: (390.57, 240.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2246)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 227, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (253.33, 128.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 877)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (489, 1147, 2266)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5820)
[M::mem_pestat] mean and std.dev: (1385.12, 1354.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7597)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 524, 1326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3554)
[M::mem_pestat] mean and std.dev: (730.39, 640.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4668)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (83, 287923, 36, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (253, 440, 914)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2236)
[M::mem_pestat] mean and std.dev: (517.92, 399.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2897)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 227, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (252.73, 127.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 873)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (315, 980, 2079)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5607)
[M::mem_pestat] mean and std.dev: (1228.41, 1053.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7371)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 321, 533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1163)
[M::mem_pestat] mean and std.dev: (305.02, 147.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1478)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705162 reads in 299.222 CPU sec, 9.498 real sec
[M::mem_process_seqs] Processed 704956 reads in 156.189 CPU sec, 4.956 real sec
[M::process] read 704766 sequences (100000206 bp) in 3.044 CPU sec, 3.146 real sec...
sorting block 31, #reads = 1086860 mem = 536882237 peak = 997609472
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 287407, 37, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 417, 927)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2433)
[M::mem_pestat] mean and std.dev: (515.08, 506.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3186)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 227, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (252.66, 127.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 873)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 655, 964)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2494)
[M::mem_pestat] mean and std.dev: (534.97, 434.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3259)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 420, 1057)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2745)
[M::mem_pestat] mean and std.dev: (587.21, 472.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3589)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 287807, 36, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 349, 1007)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2619)
[M::mem_pestat] mean and std.dev: (524.76, 432.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3425)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 226, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 686)
[M::mem_pestat] mean and std.dev: (251.60, 126.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (365, 837, 1571)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3983)
[M::mem_pestat] mean and std.dev: (861.82, 702.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5189)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 298, 764)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1886)
[M::mem_pestat] mean and std.dev: (343.48, 239.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2447)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704372 sequences (100000103 bp) in 4.186 CPU sec, 4.527 real sec...
[M::mem_process_seqs] Processed 704620 reads in 193.389 CPU sec, 6.191 real sec
[M::mem_process_seqs] Processed 704766 reads in 136.856 CPU sec, 4.335 real sec
sorting block 32, #reads = 1086837 mem = 536883017 peak = 997609472
[M::process] read 704198 sequences (100000004 bp) in 3.304 CPU sec, 3.552 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 287053, 50, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 332, 875)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2123)
[M::mem_pestat] mean and std.dev: (607.77, 540.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2769)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 227, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (251.99, 126.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 865)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (468, 544, 916)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1812)
[M::mem_pestat] mean and std.dev: (675.34, 453.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2488)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 382, 1202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3224)
[M::mem_pestat] mean and std.dev: (609.28, 590.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4235)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 287497, 34, 84)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 282, 686)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1674)
[M::mem_pestat] mean and std.dev: (440.92, 402.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2168)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 227, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (252.45, 126.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 865)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 729, 2567)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7311)
[M::mem_pestat] mean and std.dev: (1665.35, 2099.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10062)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 381, 548)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1190)
[M::mem_pestat] mean and std.dev: (357.85, 188.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1511)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704100 sequences (100000265 bp) in 2.927 CPU sec, 3.175 real sec...
[M::mem_process_seqs] Processed 704372 reads in 196.016 CPU sec, 6.219 real sec
sorting block 33, #reads = 1087288 mem = 536879324 peak = 997609472
[M::mem_process_seqs] Processed 704198 reads in 136.186 CPU sec, 4.314 real sec
[M::process] read 704590 sequences (100000227 bp) in 2.920 CPU sec, 3.087 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 287785, 27, 87)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 291, 1171)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3091)
[M::mem_pestat] mean and std.dev: (607.49, 622.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4051)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 226, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 678)
[M::mem_pestat] mean and std.dev: (250.46, 124.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 853)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 387, 1041)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2661)
[M::mem_pestat] mean and std.dev: (598.29, 567.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3471)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 446, 899)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2285)
[M::mem_pestat] mean and std.dev: (494.04, 379.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2978)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 34, #reads = 1086674 mem = 536882863 peak = 997609472
[M::process] read 704566 sequences (100000149 bp) in 2.919 CPU sec, 3.034 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 287731, 29, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 413, 1452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3980)
[M::mem_pestat] mean and std.dev: (864.00, 944.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5244)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 226, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 675)
[M::mem_pestat] mean and std.dev: (249.84, 123.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 849)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (355, 830, 2721)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7453)
[M::mem_pestat] mean and std.dev: (1577.52, 1504.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9819)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 285, 594)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1402)
[M::mem_pestat] mean and std.dev: (346.26, 270.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1806)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704100 reads in 194.205 CPU sec, 6.182 real sec
[M::mem_process_seqs] Processed 704590 reads in 133.680 CPU sec, 4.218 real sec
[M::process] read 704004 sequences (100000098 bp) in 2.699 CPU sec, 2.749 real sec...
sorting block 35, #reads = 1086633 mem = 536879920 peak = 997609472
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 287200, 32, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 262, 540)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1304)
[M::mem_pestat] mean and std.dev: (356.10, 280.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1686)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 225, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 672)
[M::mem_pestat] mean and std.dev: (248.99, 123.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 845)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 709, 1792)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4998)
[M::mem_pestat] mean and std.dev: (950.32, 961.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6601)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 369, 576)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1278)
[M::mem_pestat] mean and std.dev: (384.75, 243.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1629)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703854 sequences (100000212 bp) in 2.870 CPU sec, 2.964 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 286946, 37, 81)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 262, 998)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2622)
[M::mem_pestat] mean and std.dev: (483.56, 486.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3434)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 226, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 675)
[M::mem_pestat] mean and std.dev: (250.11, 123.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 849)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (384, 1003, 1998)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5226)
[M::mem_pestat] mean and std.dev: (1344.22, 1180.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6840)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 280, 951)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2477)
[M::mem_pestat] mean and std.dev: (418.88, 371.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3240)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702870 sequences (100000156 bp) in 2.130 CPU sec, 2.123 real sec...
[M::mem_process_seqs] Processed 704566 reads in 192.746 CPU sec, 6.109 real sec
[M::mem_process_seqs] Processed 704004 reads in 133.041 CPU sec, 4.213 real sec
sorting block 36, #reads = 1085364 mem = 536877334 peak = 997609472
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 286936, 29, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 597, 1421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3885)
[M::mem_pestat] mean and std.dev: (962.84, 1025.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5117)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 676)
[M::mem_pestat] mean and std.dev: (250.51, 123.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 850)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (114, 804, 2026)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5850)
[M::mem_pestat] mean and std.dev: (1079.14, 1150.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7762)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 390, 1072)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2752)
[M::mem_pestat] mean and std.dev: (595.79, 534.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3592)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702956 sequences (100000141 bp) in 3.433 CPU sec, 3.604 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 286692, 39, 91)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 274, 1477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4127)
[M::mem_pestat] mean and std.dev: (653.44, 885.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5452)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 229, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (252.19, 123.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 855)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (367, 904, 1382)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3412)
[M::mem_pestat] mean and std.dev: (995.92, 780.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4427)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 285, 553)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1285)
[M::mem_pestat] mean and std.dev: (329.40, 209.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1651)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703854 reads in 195.178 CPU sec, 6.208 real sec
sorting block 37, #reads = 1084873 mem = 536877119 peak = 997609472
[M::mem_process_seqs] Processed 702870 reads in 136.451 CPU sec, 4.305 real sec
[M::process] read 703012 sequences (100000124 bp) in 2.838 CPU sec, 2.897 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 287048, 32, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 387, 669)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1735)
[M::mem_pestat] mean and std.dev: (442.74, 376.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2268)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 229, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (252.26, 124.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 855)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (63, 225, 621)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1737)
[M::mem_pestat] mean and std.dev: (374.52, 368.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2295)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 350, 2063)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5787)
[M::mem_pestat] mean and std.dev: (812.53, 1013.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7649)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 38, #reads = 1085063 mem = 536878818 peak = 1014050816
[M::process] read 702752 sequences (100000124 bp) in 3.563 CPU sec, 3.874 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 286967, 40, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 385, 872)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2292)
[M::mem_pestat] mean and std.dev: (529.15, 514.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3002)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 229, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (251.78, 123.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 855)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 717, 1457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4023)
[M::mem_pestat] mean and std.dev: (766.40, 748.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5306)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 395, 1199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3229)
[M::mem_pestat] mean and std.dev: (640.05, 674.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4244)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702956 reads in 191.788 CPU sec, 6.109 real sec
[M::mem_process_seqs] Processed 703012 reads in 133.434 CPU sec, 4.217 real sec
[M::process] read 702364 sequences (100000062 bp) in 2.574 CPU sec, 2.643 real sec...
sorting block 39, #reads = 1084253 mem = 536880051 peak = 1014050816
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 286233, 34, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 309, 769)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1925)
[M::mem_pestat] mean and std.dev: (431.98, 405.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2503)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 231, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (253.87, 125.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 867)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (301, 820, 1358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3472)
[M::mem_pestat] mean and std.dev: (927.06, 849.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4529)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 350, 723)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1809)
[M::mem_pestat] mean and std.dev: (505.29, 447.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2352)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702054 sequences (100000073 bp) in 3.089 CPU sec, 3.252 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 286879, 41, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 249, 527)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1253)
[M::mem_pestat] mean and std.dev: (304.79, 245.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1616)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 231, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (254.83, 126.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 513, 1114)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3058)
[M::mem_pestat] mean and std.dev: (666.68, 686.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4030)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 401, 1059)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2667)
[M::mem_pestat] mean and std.dev: (654.33, 656.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3471)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702752 reads in 195.488 CPU sec, 6.195 real sec
[M::process] read 702118 sequences (100000221 bp) in 2.373 CPU sec, 2.385 real sec...
[M::mem_process_seqs] Processed 702364 reads in 135.836 CPU sec, 4.294 real sec
sorting block 40, #reads = 1083283 mem = 536880954 peak = 1014050816
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (103, 286815, 45, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (284, 400, 1206)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3050)
[M::mem_pestat] mean and std.dev: (581.36, 497.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3972)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 231, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (254.89, 125.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (289, 875, 1416)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3670)
[M::mem_pestat] mean and std.dev: (908.72, 699.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4797)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 310, 716)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1694)
[M::mem_pestat] mean and std.dev: (429.51, 311.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2183)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701748 sequences (100000260 bp) in 3.973 CPU sec, 4.308 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 286104, 38, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 226, 403)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 861)
[M::mem_pestat] mean and std.dev: (218.74, 92.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1090)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 232, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (256.01, 126.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 876)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 474, 860)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2050)
[M::mem_pestat] mean and std.dev: (494.97, 373.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2645)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 382, 764)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1886)
[M::mem_pestat] mean and std.dev: (405.88, 287.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2447)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702054 reads in 198.050 CPU sec, 6.272 real sec
[M::mem_process_seqs] Processed 702118 reads in 135.046 CPU sec, 4.255 real sec
sorting block 41, #reads = 1085303 mem = 536879819 peak = 1014050816
[M::process] read 702090 sequences (100000178 bp) in 2.750 CPU sec, 2.791 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 286590, 36, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 416, 1064)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2796)
[M::mem_pestat] mean and std.dev: (512.48, 539.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3662)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 232, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697)
[M::mem_pestat] mean and std.dev: (256.43, 127.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 877)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (540, 689, 892)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1596)
[M::mem_pestat] mean and std.dev: (616.67, 296.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1948)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 326, 481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1065)
[M::mem_pestat] mean and std.dev: (348.33, 250.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1357)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 42, #reads = 1083837 mem = 536877527 peak = 1034022912
[M::process] read 701972 sequences (100000286 bp) in 2.816 CPU sec, 2.892 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 286501, 39, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 424, 929)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2331)
[M::mem_pestat] mean and std.dev: (640.32, 606.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3067)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 232, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (256.29, 127.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 876)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (296, 561, 1766)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4706)
[M::mem_pestat] mean and std.dev: (913.76, 911.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6176)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 382, 1251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3371)
[M::mem_pestat] mean and std.dev: (645.57, 659.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4431)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702868 sequences (100000177 bp) in 2.260 CPU sec, 2.260 real sec...
[M::mem_process_seqs] Processed 701748 reads in 187.142 CPU sec, 5.926 real sec
[M::mem_process_seqs] Processed 702090 reads in 131.440 CPU sec, 4.154 real sec
sorting block 43, #reads = 1083798 mem = 536877572 peak = 1034022912
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 287038, 41, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 529, 1310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3510)
[M::mem_pestat] mean and std.dev: (620.24, 609.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4610)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 231, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (256.31, 127.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 880)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 505, 1463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4011)
[M::mem_pestat] mean and std.dev: (834.13, 1018.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5285)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 280, 779)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1971)
[M::mem_pestat] mean and std.dev: (534.74, 484.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2567)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 709830 sequences (100000114 bp) in 3.510 CPU sec, 3.674 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (79, 286640, 35, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 212, 566)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1360)
[M::mem_pestat] mean and std.dev: (294.30, 236.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1757)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 230, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (255.20, 127.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 875)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (445, 808, 1369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3217)
[M::mem_pestat] mean and std.dev: (974.29, 805.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4198)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 357, 1247)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3343)
[M::mem_pestat] mean and std.dev: (543.45, 561.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4391)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701972 reads in 195.743 CPU sec, 6.188 real sec
[M::process] read 711160 sequences (100000036 bp) in 2.825 CPU sec, 2.842 real sec...
[M::mem_process_seqs] Processed 702868 reads in 140.584 CPU sec, 4.440 real sec
sorting block 44, #reads = 1083858 mem = 536879647 peak = 1034022912
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 289191, 53, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 262, 860)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2236)
[M::mem_pestat] mean and std.dev: (382.73, 368.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2924)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 217, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 654)
[M::mem_pestat] mean and std.dev: (241.08, 120.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 823)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (482, 916, 3507)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9557)
[M::mem_pestat] mean and std.dev: (1898.13, 2033.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12582)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 410, 1151)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3007)
[M::mem_pestat] mean and std.dev: (605.40, 602.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3935)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 710346 sequences (100000030 bp) in 2.884 CPU sec, 3.022 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 289580, 38, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 297, 1033)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2781)
[M::mem_pestat] mean and std.dev: (532.59, 542.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3655)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 214, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 646)
[M::mem_pestat] mean and std.dev: (238.24, 119.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 813)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (289, 610, 1260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3202)
[M::mem_pestat] mean and std.dev: (757.69, 638.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4173)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 334, 870)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2156)
[M::mem_pestat] mean and std.dev: (503.04, 481.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2799)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 710302 sequences (100000281 bp) in 2.400 CPU sec, 2.397 real sec...
[M::mem_process_seqs] Processed 709830 reads in 194.927 CPU sec, 6.183 real sec
sorting block 45, #reads = 1083283 mem = 536881101 peak = 1034022912
[M::mem_process_seqs] Processed 711160 reads in 133.043 CPU sec, 4.215 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 289449, 37, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 276, 985)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2569)
[M::mem_pestat] mean and std.dev: (530.03, 450.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3361)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 216, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 656)
[M::mem_pestat] mean and std.dev: (240.70, 120.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 826)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (108, 500, 859)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2361)
[M::mem_pestat] mean and std.dev: (623.77, 627.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3136)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 403, 717)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1777)
[M::mem_pestat] mean and std.dev: (451.46, 381.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2307)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 46, #reads = 1091253 mem = 536881129 peak = 1034022912
[M::process] read 710476 sequences (100000052 bp) in 3.745 CPU sec, 3.968 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (90, 289833, 41, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 321, 1695)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4661)
[M::mem_pestat] mean and std.dev: (855.01, 930.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6144)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 216, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 656)
[M::mem_pestat] mean and std.dev: (240.48, 120.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 826)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (452, 782, 3199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8693)
[M::mem_pestat] mean and std.dev: (1861.07, 2073.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11440)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 404, 1712)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4674)
[M::mem_pestat] mean and std.dev: (953.27, 988.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6155)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 710346 reads in 197.251 CPU sec, 6.245 real sec
[M::process] read 708662 sequences (100000133 bp) in 2.682 CPU sec, 2.722 real sec...
[M::mem_process_seqs] Processed 710302 reads in 137.018 CPU sec, 4.325 real sec
sorting block 47, #reads = 1089345 mem = 536880194 peak = 1034022912
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 289846, 38, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 267, 642)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1628)
[M::mem_pestat] mean and std.dev: (395.81, 364.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2121)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 215, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 655)
[M::mem_pestat] mean and std.dev: (240.10, 120.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 825)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (73, 1108, 1905)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5569)
[M::mem_pestat] mean and std.dev: (1159.18, 1104.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7401)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 410, 1084)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2858)
[M::mem_pestat] mean and std.dev: (518.97, 569.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3745)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708242 sequences (100000106 bp) in 2.985 CPU sec, 3.104 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 289171, 31, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (266, 378, 725)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1643)
[M::mem_pestat] mean and std.dev: (425.89, 285.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2102)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 219, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (243.02, 121.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 832)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (671, 1266, 2429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5945)
[M::mem_pestat] mean and std.dev: (1245.48, 912.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7703)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 354, 713)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1723)
[M::mem_pestat] mean and std.dev: (500.83, 450.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2301)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707452 sequences (100000209 bp) in 2.356 CPU sec, 2.358 real sec...
[M::mem_process_seqs] Processed 710476 reads in 195.594 CPU sec, 6.203 real sec
[M::mem_process_seqs] Processed 708662 reads in 133.240 CPU sec, 4.218 real sec
sorting block 48, #reads = 1090749 mem = 536880612 peak = 1034022912
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 288636, 34, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 413, 2543)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7235)
[M::mem_pestat] mean and std.dev: (1659.54, 2340.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11021)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 220, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (243.73, 121.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 832)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (546, 1143, 1608)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3732)
[M::mem_pestat] mean and std.dev: (1145.34, 719.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4794)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 269, 704)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1744)
[M::mem_pestat] mean and std.dev: (362.67, 312.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2264)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706936 sequences (100000064 bp) in 3.174 CPU sec, 3.269 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 288985, 25, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 384, 860)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2232)
[M::mem_pestat] mean and std.dev: (558.09, 488.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2918)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 222, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (245.75, 122.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 845)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1032, 1224, 2557)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5607)
[M::mem_pestat] mean and std.dev: (1847.52, 1452.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7657)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 324, 734)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1888)
[M::mem_pestat] mean and std.dev: (406.33, 356.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2465)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706334 sequences (100000104 bp) in 2.350 CPU sec, 2.348 real sec...
[M::mem_process_seqs] Processed 708242 reads in 197.315 CPU sec, 6.465 real sec
[M::mem_process_seqs] Processed 707452 reads in 130.785 CPU sec, 4.150 real sec
sorting block 49, #reads = 1088582 mem = 536880003 peak = 1034022912
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 288232, 30, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 286, 618)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1410)
[M::mem_pestat] mean and std.dev: (389.38, 278.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1806)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 223, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 675)
[M::mem_pestat] mean and std.dev: (247.40, 123.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 850)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (358, 1086, 4617)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13135)
[M::mem_pestat] mean and std.dev: (2920.23, 3301.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17394)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 320, 809)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1957)
[M::mem_pestat] mean and std.dev: (458.78, 403.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2531)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705590 sequences (100000253 bp) in 3.317 CPU sec, 3.432 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 288032, 27, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 417, 792)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1954)
[M::mem_pestat] mean and std.dev: (507.56, 440.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2535)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 224, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (248.88, 124.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 859)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 1738, 1980)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5534)
[M::mem_pestat] mean and std.dev: (1469.85, 1367.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7311)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (286, 484, 1038)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2542)
[M::mem_pestat] mean and std.dev: (595.82, 442.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3294)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706936 reads in 192.181 CPU sec, 6.086 real sec
sorting block 50, #reads = 1089181 mem = 536877023 peak = 1034022912
[M::process] read 705566 sequences (100000084 bp) in 2.570 CPU sec, 2.596 real sec...
[M::mem_process_seqs] Processed 706334 reads in 133.206 CPU sec, 4.208 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 287491, 37, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 414, 1009)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2599)
[M::mem_pestat] mean and std.dev: (538.56, 496.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3394)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 226, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 677)
[M::mem_pestat] mean and std.dev: (249.19, 123.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 852)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (628, 1999, 2509)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6271)
[M::mem_pestat] mean and std.dev: (1975.83, 1495.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8152)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 284, 1180)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3150)
[M::mem_pestat] mean and std.dev: (705.38, 697.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4135)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 51, #reads = 1087642 mem = 536876861 peak = 1089048576
[M::process] read 705144 sequences (100000048 bp) in 3.634 CPU sec, 3.829 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 288187, 27, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 233, 529)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1287)
[M::mem_pestat] mean and std.dev: (320.89, 240.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1666)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 226, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (249.75, 124.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 856)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (364, 658, 1837)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4783)
[M::mem_pestat] mean and std.dev: (970.00, 846.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6256)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (275, 525, 929)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2237)
[M::mem_pestat] mean and std.dev: (640.21, 510.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2891)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705590 reads in 195.727 CPU sec, 6.216 real sec
[M::mem_process_seqs] Processed 705566 reads in 134.771 CPU sec, 4.256 real sec
[M::process] read 704544 sequences (100000295 bp) in 2.830 CPU sec, 2.906 real sec...
sorting block 52, #reads = 1087865 mem = 536879334 peak = 1089048576
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 287570, 29, 86)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 325, 686)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1626)
[M::mem_pestat] mean and std.dev: (385.19, 302.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2096)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 227, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (251.76, 125.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (70, 334, 1096)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3148)
[M::mem_pestat] mean and std.dev: (621.23, 715.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4174)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 338, 703)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1699)
[M::mem_pestat] mean and std.dev: (340.21, 231.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2197)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704806 sequences (100000182 bp) in 3.232 CPU sec, 3.340 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 287745, 28, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 386, 1078)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2884)
[M::mem_pestat] mean and std.dev: (678.66, 731.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3787)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 228, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (251.87, 124.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 865)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 695, 1857)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5113)
[M::mem_pestat] mean and std.dev: (791.12, 867.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6741)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (259, 364, 942)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2308)
[M::mem_pestat] mean and std.dev: (600.80, 543.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2991)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705144 reads in 195.487 CPU sec, 6.247 real sec
[M::mem_process_seqs] Processed 704544 reads in 134.897 CPU sec, 4.262 real sec
[M::process] read 704688 sequences (100000244 bp) in 2.831 CPU sec, 2.888 real sec...
sorting block 53, #reads = 1086763 mem = 536879458 peak = 1089048576
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 287678, 44, 84)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 590, 987)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2491)
[M::mem_pestat] mean and std.dev: (582.93, 451.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3243)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 227, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684)
[M::mem_pestat] mean and std.dev: (251.26, 124.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 861)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 413, 1389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3829)
[M::mem_pestat] mean and std.dev: (754.32, 790.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5049)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 269, 534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1226)
[M::mem_pestat] mean and std.dev: (301.85, 206.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1572)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704292 sequences (100000111 bp) in 3.378 CPU sec, 3.518 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 288214, 35, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 365, 1251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3383)
[M::mem_pestat] mean and std.dev: (651.00, 676.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4449)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 228, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (252.38, 126.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 869)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 422, 1001)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2711)
[M::mem_pestat] mean and std.dev: (560.59, 439.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3566)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 595, 1174)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3080)
[M::mem_pestat] mean and std.dev: (708.78, 693.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4033)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704806 reads in 199.304 CPU sec, 6.340 real sec
sorting block 54, #reads = 1087380 mem = 536888502 peak = 1089048576
[M::mem_process_seqs] Processed 704688 reads in 137.925 CPU sec, 4.353 real sec
[M::process] read 704132 sequences (100000121 bp) in 2.674 CPU sec, 2.708 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 287530, 44, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 506, 1357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3607)
[M::mem_pestat] mean and std.dev: (792.19, 840.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4732)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 229, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (252.96, 126.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 873)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (357, 588, 1573)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4005)
[M::mem_pestat] mean and std.dev: (971.67, 936.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5221)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 274, 656)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1592)
[M::mem_pestat] mean and std.dev: (368.18, 265.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2060)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 55, #reads = 1086901 mem = 536878286 peak = 1089048576
[M::process] read 704608 sequences (100000248 bp) in 3.170 CPU sec, 3.249 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 287467, 42, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 343, 1150)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3094)
[M::mem_pestat] mean and std.dev: (635.33, 632.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4066)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 229, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (253.16, 126.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 425, 970)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2490)
[M::mem_pestat] mean and std.dev: (518.13, 430.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3250)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 400, 1000)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2614)
[M::mem_pestat] mean and std.dev: (674.32, 660.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3421)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704292 reads in 192.915 CPU sec, 6.141 real sec
[M::mem_process_seqs] Processed 704132 reads in 135.093 CPU sec, 4.248 real sec
[M::process] read 703862 sequences (100000223 bp) in 2.708 CPU sec, 2.736 real sec...
sorting block 56, #reads = 1086858 mem = 536880025 peak = 1089048576
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 287259, 38, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 337, 721)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1803)
[M::mem_pestat] mean and std.dev: (414.96, 334.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2344)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 226, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 675)
[M::mem_pestat] mean and std.dev: (249.35, 123.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 849)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 801, 1927)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5447)
[M::mem_pestat] mean and std.dev: (1166.11, 1401.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7207)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 313, 672)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1646)
[M::mem_pestat] mean and std.dev: (389.45, 296.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2133)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703664 sequences (100000180 bp) in 3.371 CPU sec, 3.501 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 287044, 36, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 309, 478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1088)
[M::mem_pestat] mean and std.dev: (304.97, 184.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1393)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (251.29, 124.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (472, 786, 1893)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4735)
[M::mem_pestat] mean and std.dev: (1074.91, 1013.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6156)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 332, 625)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1505)
[M::mem_pestat] mean and std.dev: (390.95, 299.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1945)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704608 reads in 194.465 CPU sec, 6.166 real sec
[M::process] read 703808 sequences (100000020 bp) in 2.451 CPU sec, 2.463 real sec...
[M::mem_process_seqs] Processed 703862 reads in 133.251 CPU sec, 4.208 real sec
sorting block 57, #reads = 1086024 mem = 536878329 peak = 1089048576
[M::process] read 703454 sequences (100000047 bp) in 3.234 CPU sec, 3.392 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 286936, 34, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 294, 1511)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4173)
[M::mem_pestat] mean and std.dev: (907.93, 1094.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5504)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (250.74, 123.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 599, 1023)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2751)
[M::mem_pestat] mean and std.dev: (490.29, 431.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3615)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 340, 1277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3381)
[M::mem_pestat] mean and std.dev: (625.97, 532.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4433)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703808 reads in 111.628 CPU sec, 3.514 real sec
[M::process] read 703706 sequences (100000146 bp) in 2.500 CPU sec, 2.509 real sec...
sorting block 58, #reads = 1084711 mem = 536880385 peak = 1089048576
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 286916, 31, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 370, 677)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1637)
[M::mem_pestat] mean and std.dev: (448.67, 324.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2117)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (251.51, 124.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (534, 1032, 1761)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4215)
[M::mem_pestat] mean and std.dev: (1123.43, 776.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5442)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 356, 1417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3749)
[M::mem_pestat] mean and std.dev: (662.01, 644.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4915)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 286349, 33, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 292, 636)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1614)
[M::mem_pestat] mean and std.dev: (364.19, 310.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2103)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (251.55, 124.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (269, 574, 1454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3824)
[M::mem_pestat] mean and std.dev: (744.80, 767.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5009)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 324, 886)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2166)
[M::mem_pestat] mean and std.dev: (546.77, 502.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2806)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703664 reads in 311.413 CPU sec, 9.903 real sec
[M::process] read 702962 sequences (100000155 bp) in 2.652 CPU sec, 2.694 real sec...
[M::mem_process_seqs] Processed 703454 reads in 165.609 CPU sec, 5.262 real sec
sorting block 59, #reads = 1084608 mem = 536880368 peak = 1089048576
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 287453, 29, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 333, 862)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2204)
[M::mem_pestat] mean and std.dev: (435.38, 371.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2875)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (251.15, 124.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (647, 919, 1800)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4106)
[M::mem_pestat] mean and std.dev: (890.20, 560.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5259)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 325, 626)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1530)
[M::mem_pestat] mean and std.dev: (384.17, 331.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1982)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703418 sequences (100000227 bp) in 3.893 CPU sec, 4.087 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 287194, 38, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 497, 983)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2529)
[M::mem_pestat] mean and std.dev: (577.50, 523.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3302)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 230, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 686)
[M::mem_pestat] mean and std.dev: (253.37, 125.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 863)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (117, 370, 817)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2217)
[M::mem_pestat] mean and std.dev: (450.05, 416.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2917)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 324, 651)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1465)
[M::mem_pestat] mean and std.dev: (431.00, 321.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1872)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703706 reads in 195.452 CPU sec, 6.219 real sec
[M::mem_process_seqs] Processed 702962 reads in 134.668 CPU sec, 4.257 real sec
sorting block 60, #reads = 1084132 mem = 536878695 peak = 1089048576
[M::process] read 702378 sequences (100000296 bp) in 3.132 CPU sec, 3.242 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (81, 287411, 28, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 275, 872)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2316)
[M::mem_pestat] mean and std.dev: (501.37, 527.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3038)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (251.77, 123.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (409, 767, 1162)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2668)
[M::mem_pestat] mean and std.dev: (675.75, 529.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3421)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 352, 916)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2284)
[M::mem_pestat] mean and std.dev: (579.39, 561.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2968)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 61, #reads = 1085042 mem = 536879618 peak = 1089048576
[M::process] read 702720 sequences (100000048 bp) in 3.281 CPU sec, 3.407 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 286420, 32, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 306, 464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 994)
[M::mem_pestat] mean and std.dev: (280.77, 150.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1259)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 231, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 681)
[M::mem_pestat] mean and std.dev: (252.92, 123.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 856)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (604, 1514, 3789)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10159)
[M::mem_pestat] mean and std.dev: (2493.78, 2651.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13344)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 305, 852)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2160)
[M::mem_pestat] mean and std.dev: (408.61, 430.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2814)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703418 reads in 191.913 CPU sec, 6.105 real sec
[M::process] read 702818 sequences (100000086 bp) in 2.149 CPU sec, 2.191 real sec...
[M::mem_process_seqs] Processed 702378 reads in 134.257 CPU sec, 4.242 real sec
sorting block 62, #reads = 1084746 mem = 536879671 peak = 1089048576
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (89, 286881, 32, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 581, 1284)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3428)
[M::mem_pestat] mean and std.dev: (724.08, 624.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4500)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 230, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (252.97, 124.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 859)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (398, 635, 3140)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8624)
[M::mem_pestat] mean and std.dev: (1566.03, 1746.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11366)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 334, 1086)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2790)
[M::mem_pestat] mean and std.dev: (740.47, 678.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3642)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702902 sequences (100000186 bp) in 2.826 CPU sec, 2.926 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 286968, 45, 88)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 395, 1910)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5266)
[M::mem_pestat] mean and std.dev: (859.89, 961.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6944)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 230, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684)
[M::mem_pestat] mean and std.dev: (253.51, 125.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 860)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (380, 663, 2629)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7127)
[M::mem_pestat] mean and std.dev: (1212.57, 1252.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9376)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 408, 844)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2112)
[M::mem_pestat] mean and std.dev: (578.92, 486.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2746)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702470 sequences (100000015 bp) in 2.430 CPU sec, 2.430 real sec...
[M::mem_process_seqs] Processed 702720 reads in 191.885 CPU sec, 6.094 real sec
[M::mem_process_seqs] Processed 702818 reads in 134.307 CPU sec, 4.254 real sec
sorting block 63, #reads = 1083740 mem = 536876998 peak = 1089048576
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 286762, 41, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 280, 877)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2265)
[M::mem_pestat] mean and std.dev: (474.60, 472.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2959)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 229, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 686)
[M::mem_pestat] mean and std.dev: (253.38, 125.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 863)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (546, 983, 1912)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4644)
[M::mem_pestat] mean and std.dev: (1134.15, 793.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6010)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 356, 1278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3378)
[M::mem_pestat] mean and std.dev: (689.55, 673.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4428)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702748 sequences (100000058 bp) in 3.509 CPU sec, 3.640 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 287521, 29, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 355, 1345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3673)
[M::mem_pestat] mean and std.dev: (833.96, 1037.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4982)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 229, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (253.81, 125.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 867)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (262, 507, 1257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3247)
[M::mem_pestat] mean and std.dev: (694.89, 631.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4242)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 440, 1104)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2882)
[M::mem_pestat] mean and std.dev: (713.25, 696.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3771)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702902 reads in 194.823 CPU sec, 6.168 real sec
[M::process] read 702704 sequences (100000057 bp) in 2.532 CPU sec, 2.544 real sec...
[M::mem_process_seqs] Processed 702470 reads in 135.488 CPU sec, 4.277 real sec
sorting block 64, #reads = 1082525 mem = 536885705 peak = 1089048576
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 286426, 33, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 293, 999)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2637)
[M::mem_pestat] mean and std.dev: (619.32, 615.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3456)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 230, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (253.88, 126.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 867)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 484, 1677)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4697)
[M::mem_pestat] mean and std.dev: (801.39, 803.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6207)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 274, 1073)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2835)
[M::mem_pestat] mean and std.dev: (523.02, 550.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3716)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702454 sequences (100000111 bp) in 3.348 CPU sec, 3.456 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 287024, 29, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 235, 819)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2147)
[M::mem_pestat] mean and std.dev: (445.08, 456.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2811)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 229, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (253.60, 125.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 867)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 960, 1620)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4528)
[M::mem_pestat] mean and std.dev: (1005.93, 1002.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5982)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 273, 872)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2216)
[M::mem_pestat] mean and std.dev: (436.35, 403.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2888)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702748 reads in 192.249 CPU sec, 6.093 real sec
sorting block 65, #reads = 1082488 mem = 536878052 peak = 1089048576
[M::process] read 704386 sequences (100000034 bp) in 2.639 CPU sec, 2.660 real sec...
[M::mem_process_seqs] Processed 702704 reads in 135.231 CPU sec, 4.268 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 286806, 39, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 231, 682)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1692)
[M::mem_pestat] mean and std.dev: (352.76, 335.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2197)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 230, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 681)
[M::mem_pestat] mean and std.dev: (253.35, 125.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 856)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (344, 852, 1439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3629)
[M::mem_pestat] mean and std.dev: (959.11, 853.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4724)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 324, 769)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1909)
[M::mem_pestat] mean and std.dev: (455.44, 423.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2479)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 66, #reads = 1082964 mem = 536878839 peak = 1126559744
[M::process] read 710576 sequences (100000103 bp) in 3.448 CPU sec, 3.566 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 287441, 28, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 349, 792)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1974)
[M::mem_pestat] mean and std.dev: (440.84, 362.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2565)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 226, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 678)
[M::mem_pestat] mean and std.dev: (250.19, 124.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 853)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (420, 550, 1160)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2640)
[M::mem_pestat] mean and std.dev: (861.82, 632.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3391)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 369, 807)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1991)
[M::mem_pestat] mean and std.dev: (528.26, 438.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2583)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702454 reads in 197.030 CPU sec, 6.257 real sec
[M::process] read 709706 sequences (100000225 bp) in 2.546 CPU sec, 2.568 real sec...
[M::mem_process_seqs] Processed 704386 reads in 139.731 CPU sec, 4.413 real sec
sorting block 67, #reads = 1083266 mem = 536880722 peak = 1126559744
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 289601, 31, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 342, 705)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1753)
[M::mem_pestat] mean and std.dev: (443.48, 352.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2277)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 215, 314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 652)
[M::mem_pestat] mean and std.dev: (239.36, 119.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 821)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (656, 1310, 2246)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5426)
[M::mem_pestat] mean and std.dev: (1441.64, 1385.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7016)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 339, 775)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1973)
[M::mem_pestat] mean and std.dev: (446.43, 397.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2572)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 709194 sequences (100000277 bp) in 3.500 CPU sec, 3.634 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (83, 289123, 37, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 336, 979)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2557)
[M::mem_pestat] mean and std.dev: (561.13, 561.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3346)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 217, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 659)
[M::mem_pestat] mean and std.dev: (241.41, 121.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 830)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (410, 739, 1695)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4265)
[M::mem_pestat] mean and std.dev: (1038.53, 934.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5550)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 310, 434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 844)
[M::mem_pestat] mean and std.dev: (317.14, 152.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1049)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 710576 reads in 190.592 CPU sec, 6.047 real sec
[M::process] read 709058 sequences (100000198 bp) in 2.652 CPU sec, 2.665 real sec...
[M::mem_process_seqs] Processed 709706 reads in 132.357 CPU sec, 4.174 real sec
sorting block 68, #reads = 1085310 mem = 536880781 peak = 1126559744
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 289031, 32, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 326, 795)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2043)
[M::mem_pestat] mean and std.dev: (433.35, 393.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2667)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 218, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 660)
[M::mem_pestat] mean and std.dev: (242.30, 121.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 831)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 657, 1217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3255)
[M::mem_pestat] mean and std.dev: (626.27, 492.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4274)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 423, 979)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2613)
[M::mem_pestat] mean and std.dev: (544.70, 504.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3430)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708762 sequences (100000019 bp) in 3.468 CPU sec, 3.611 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 288707, 27, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 277, 1204)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3238)
[M::mem_pestat] mean and std.dev: (669.95, 771.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4255)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 218, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 663)
[M::mem_pestat] mean and std.dev: (242.55, 121.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 835)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (125, 521, 1497)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4241)
[M::mem_pestat] mean and std.dev: (792.11, 807.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5613)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 403, 664)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1602)
[M::mem_pestat] mean and std.dev: (402.67, 314.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2071)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 709194 reads in 188.042 CPU sec, 5.972 real sec
sorting block 69, #reads = 1090090 mem = 536876993 peak = 1126559744
[M::mem_process_seqs] Processed 709058 reads in 133.128 CPU sec, 4.192 real sec
[M::process] read 708260 sequences (100000251 bp) in 2.652 CPU sec, 2.673 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 288820, 36, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 348, 833)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2095)
[M::mem_pestat] mean and std.dev: (467.88, 430.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2726)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 219, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (243.40, 121.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 832)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (433, 1180, 2019)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5191)
[M::mem_pestat] mean and std.dev: (1335.89, 1159.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6777)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (272, 430, 1194)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3038)
[M::mem_pestat] mean and std.dev: (690.81, 607.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3960)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 70, #reads = 1090605 mem = 536876523 peak = 1126559744
[M::process] read 707844 sequences (100000280 bp) in 3.015 CPU sec, 3.138 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 288785, 37, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 281, 717)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1769)
[M::mem_pestat] mean and std.dev: (412.22, 352.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2295)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 220, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 670)
[M::mem_pestat] mean and std.dev: (244.73, 122.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 844)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (464, 652, 1960)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4952)
[M::mem_pestat] mean and std.dev: (1254.14, 1208.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6448)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 532, 1185)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3119)
[M::mem_pestat] mean and std.dev: (785.74, 750.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4086)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 708762 reads in 181.854 CPU sec, 5.792 real sec
[M::process] read 708026 sequences (100000144 bp) in 1.953 CPU sec, 1.957 real sec...
[M::mem_process_seqs] Processed 708260 reads in 133.625 CPU sec, 4.255 real sec
sorting block 71, #reads = 1090225 mem = 536878207 peak = 1126559744
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 289097, 34, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 396, 1236)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3298)
[M::mem_pestat] mean and std.dev: (606.20, 513.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4329)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 222, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (245.79, 122.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 845)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 826, 1522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4202)
[M::mem_pestat] mean and std.dev: (809.82, 602.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5542)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 241, 961)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2519)
[M::mem_pestat] mean and std.dev: (471.33, 542.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3298)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706766 sequences (100000126 bp) in 2.975 CPU sec, 3.134 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 288640, 43, 81)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 243, 509)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1215)
[M::mem_pestat] mean and std.dev: (279.09, 213.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1568)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 222, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (246.17, 123.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 849)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (441, 1242, 3037)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8229)
[M::mem_pestat] mean and std.dev: (1725.88, 1661.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10825)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 367, 904)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2322)
[M::mem_pestat] mean and std.dev: (520.57, 488.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3031)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707844 reads in 186.488 CPU sec, 5.920 real sec
[M::process] read 706216 sequences (100000014 bp) in 2.403 CPU sec, 2.408 real sec...
[M::mem_process_seqs] Processed 708026 reads in 127.471 CPU sec, 4.034 real sec
sorting block 72, #reads = 1089274 mem = 536877716 peak = 1126559744
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 288109, 33, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 433, 1028)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2690)
[M::mem_pestat] mean and std.dev: (626.42, 507.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3521)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 223, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 678)
[M::mem_pestat] mean and std.dev: (248.13, 124.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (386, 699, 746)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1466)
[M::mem_pestat] mean and std.dev: (599.90, 340.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1960)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 291, 1084)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2856)
[M::mem_pestat] mean and std.dev: (558.50, 521.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3742)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705840 sequences (100000195 bp) in 3.118 CPU sec, 3.232 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 288013, 25, 92)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 331, 1177)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3147)
[M::mem_pestat] mean and std.dev: (648.01, 671.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4132)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 225, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (250.10, 125.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 863)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 430, 1052)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2848)
[M::mem_pestat] mean and std.dev: (659.68, 662.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3746)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 332, 803)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1981)
[M::mem_pestat] mean and std.dev: (455.16, 363.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2570)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706766 reads in 188.958 CPU sec, 6.006 real sec
[M::process] read 705424 sequences (100000008 bp) in 2.619 CPU sec, 2.673 real sec...
sorting block 73, #reads = 1089137 mem = 536876823 peak = 1126559744
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 288283, 25, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 233, 636)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1578)
[M::mem_pestat] mean and std.dev: (307.00, 278.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2049)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 226, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (250.94, 125.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 867)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (510, 578, 912)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1716)
[M::mem_pestat] mean and std.dev: (606.74, 389.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2164)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (299, 990, 2252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6158)
[M::mem_pestat] mean and std.dev: (1421.82, 1417.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8111)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705604 sequences (100000026 bp) in 2.529 CPU sec, 2.538 real sec...
[M::mem_process_seqs] Processed 705840 reads in 109.552 CPU sec, 3.599 real sec
sorting block 74, #reads = 1088533 mem = 536880739 peak = 1126559744
[M::mem_process_seqs] Processed 706216 reads in 269.079 CPU sec, 8.656 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 287991, 36, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 303, 859)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2149)
[M::mem_pestat] mean and std.dev: (560.19, 554.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2794)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 227, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (250.61, 125.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 860)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (706, 979, 2203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5197)
[M::mem_pestat] mean and std.dev: (1309.09, 894.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6694)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 245, 595)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1451)
[M::mem_pestat] mean and std.dev: (318.12, 255.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1879)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705618 sequences (100000123 bp) in 3.208 CPU sec, 3.331 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 288067, 36, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 385, 2793)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7921)
[M::mem_pestat] mean and std.dev: (1487.43, 1924.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10485)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 226, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (250.43, 124.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 860)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (474, 1622, 2526)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6630)
[M::mem_pestat] mean and std.dev: (1524.22, 1147.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8682)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 406, 1519)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4181)
[M::mem_pestat] mean and std.dev: (898.78, 1062.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5512)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705424 reads in 207.887 CPU sec, 6.584 real sec
sorting block 75, #reads = 1088011 mem = 536878434 peak = 1126559744
[M::mem_process_seqs] Processed 705604 reads in 128.320 CPU sec, 4.041 real sec
[M::process] read 704870 sequences (100000293 bp) in 2.678 CPU sec, 2.765 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 288088, 33, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 320, 1004)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2672)
[M::mem_pestat] mean and std.dev: (598.09, 598.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3506)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 227, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 686)
[M::mem_pestat] mean and std.dev: (251.10, 125.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 461, 805)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2035)
[M::mem_pestat] mean and std.dev: (536.69, 490.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2650)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 482, 816)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1944)
[M::mem_pestat] mean and std.dev: (498.64, 362.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2508)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 76, #reads = 1086456 mem = 536879153 peak = 1126559744
[M::process] read 705334 sequences (100000258 bp) in 3.366 CPU sec, 3.491 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 287770, 42, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 348, 866)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2220)
[M::mem_pestat] mean and std.dev: (399.00, 319.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2897)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 228, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (252.22, 125.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 869)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (456, 970, 2877)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7719)
[M::mem_pestat] mean and std.dev: (2064.00, 2324.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11362)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 277, 582)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1370)
[M::mem_pestat] mean and std.dev: (390.00, 307.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1764)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705618 reads in 192.077 CPU sec, 6.098 real sec
[M::mem_process_seqs] Processed 704870 reads in 134.402 CPU sec, 4.246 real sec
[M::process] read 704974 sequences (100000094 bp) in 2.682 CPU sec, 2.733 real sec...
sorting block 77, #reads = 1085999 mem = 536880407 peak = 1126559744
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 287327, 35, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 310, 1167)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3159)
[M::mem_pestat] mean and std.dev: (619.52, 717.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4155)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 227, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (251.66, 125.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (361, 609, 3961)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11161)
[M::mem_pestat] mean and std.dev: (2046.51, 2702.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14761)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 345, 778)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1912)
[M::mem_pestat] mean and std.dev: (443.00, 359.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2479)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706026 sequences (100000165 bp) in 3.556 CPU sec, 3.719 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (79, 287966, 29, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 337, 647)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1615)
[M::mem_pestat] mean and std.dev: (401.31, 337.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2099)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 226, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 686)
[M::mem_pestat] mean and std.dev: (251.08, 125.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (752, 905, 1830)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3986)
[M::mem_pestat] mean and std.dev: (1028.42, 683.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5064)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 377, 650)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1482)
[M::mem_pestat] mean and std.dev: (414.39, 265.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1898)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705334 reads in 193.160 CPU sec, 6.142 real sec
[M::mem_process_seqs] Processed 704974 reads in 135.455 CPU sec, 4.274 real sec
[M::process] read 707048 sequences (100000138 bp) in 2.649 CPU sec, 2.727 real sec...
sorting block 78, #reads = 1085268 mem = 536879381 peak = 1126559744
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 287359, 49, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 262, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 703)
[M::mem_pestat] mean and std.dev: (255.26, 120.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 223, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 673)
[M::mem_pestat] mean and std.dev: (248.26, 124.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 847)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (352, 1306, 2116)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5644)
[M::mem_pestat] mean and std.dev: (1317.98, 1122.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7408)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 334, 838)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2120)
[M::mem_pestat] mean and std.dev: (474.29, 416.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2761)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704704 sequences (100000210 bp) in 3.432 CPU sec, 3.569 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 288440, 17, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 283, 681)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1721)
[M::mem_pestat] mean and std.dev: (381.05, 332.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2241)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 219, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 650)
[M::mem_pestat] mean and std.dev: (242.48, 119.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 817)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (313, 934, 2574)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7096)
[M::mem_pestat] mean and std.dev: (1347.12, 1331.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9357)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 292, 1159)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3107)
[M::mem_pestat] mean and std.dev: (620.98, 710.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4081)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706026 reads in 200.186 CPU sec, 6.382 real sec
[M::mem_process_seqs] Processed 707048 reads in 141.057 CPU sec, 4.456 real sec
[M::process] read 705092 sequences (100000168 bp) in 2.986 CPU sec, 3.062 real sec...
sorting block 79, #reads = 1086564 mem = 536878351 peak = 1126559744
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 287987, 38, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 279, 929)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2493)
[M::mem_pestat] mean and std.dev: (544.07, 600.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3275)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 225, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 669)
[M::mem_pestat] mean and std.dev: (248.58, 122.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 841)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (502, 982, 4221)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11659)
[M::mem_pestat] mean and std.dev: (2060.34, 2136.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 15378)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 291, 770)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1898)
[M::mem_pestat] mean and std.dev: (405.77, 349.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2462)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 80, #reads = 1087173 mem = 536877387 peak = 1126559744
[M::process] read 703838 sequences (100000197 bp) in 3.538 CPU sec, 3.716 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 287826, 38, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 279, 816)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2094)
[M::mem_pestat] mean and std.dev: (538.56, 505.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2733)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (247.30, 122.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 840)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 745, 1287)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3417)
[M::mem_pestat] mean and std.dev: (762.61, 722.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4482)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 303, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 943)
[M::mem_pestat] mean and std.dev: (348.60, 196.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1181)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704704 reads in 196.400 CPU sec, 6.266 real sec
[M::mem_process_seqs] Processed 705092 reads in 139.603 CPU sec, 4.408 real sec
[M::process] read 703936 sequences (100000136 bp) in 2.883 CPU sec, 2.973 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (84, 287189, 25, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 400, 921)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2399)
[M::mem_pestat] mean and std.dev: (500.38, 456.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3138)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 226, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 672)
[M::mem_pestat] mean and std.dev: (249.30, 122.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 845)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (496, 1047, 3386)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9166)
[M::mem_pestat] mean and std.dev: (1839.12, 1876.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12056)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 308, 1010)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2708)
[M::mem_pestat] mean and std.dev: (556.12, 564.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3557)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 81, #reads = 1085326 mem = 536877388 peak = 1126559744
[M::process] read 703252 sequences (100000123 bp) in 3.335 CPU sec, 3.459 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 286750, 32, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 478, 786)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1952)
[M::mem_pestat] mean and std.dev: (524.18, 464.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2535)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 226, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 672)
[M::mem_pestat] mean and std.dev: (249.22, 122.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 845)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (401, 727, 1789)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4565)
[M::mem_pestat] mean and std.dev: (871.89, 707.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5953)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 397, 687)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1639)
[M::mem_pestat] mean and std.dev: (386.43, 277.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2115)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703838 reads in 199.307 CPU sec, 6.350 real sec
[M::process] read 703512 sequences (100000078 bp) in 2.649 CPU sec, 2.695 real sec...
[M::mem_process_seqs] Processed 703936 reads in 141.222 CPU sec, 4.456 real sec
sorting block 82, #reads = 1084270 mem = 536880137 peak = 1126559744
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (87, 287047, 33, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 475, 1062)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2772)
[M::mem_pestat] mean and std.dev: (736.75, 729.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3656)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 670)
[M::mem_pestat] mean and std.dev: (249.63, 121.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 842)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (342, 584, 2159)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5793)
[M::mem_pestat] mean and std.dev: (1160.58, 1039.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7610)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 362, 1416)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3880)
[M::mem_pestat] mean and std.dev: (781.83, 842.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5112)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703358 sequences (100000211 bp) in 3.025 CPU sec, 3.157 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 286694, 43, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 373, 558)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1372)
[M::mem_pestat] mean and std.dev: (340.77, 253.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1779)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 673)
[M::mem_pestat] mean and std.dev: (250.06, 122.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 846)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (318, 804, 1463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3753)
[M::mem_pestat] mean and std.dev: (1053.02, 944.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4898)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 380, 644)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1442)
[M::mem_pestat] mean and std.dev: (442.68, 301.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1841)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703030 sequences (100000008 bp) in 2.330 CPU sec, 2.335 real sec...
[M::mem_process_seqs] Processed 703252 reads in 198.171 CPU sec, 6.288 real sec
[M::mem_process_seqs] Processed 703512 reads in 139.395 CPU sec, 4.425 real sec
sorting block 83, #reads = 1083856 mem = 536878249 peak = 1126559744
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 286863, 39, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 347, 930)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2348)
[M::mem_pestat] mean and std.dev: (630.58, 650.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3235)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 227, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (249.84, 121.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 839)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (699, 1006, 2289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5469)
[M::mem_pestat] mean and std.dev: (1219.40, 1034.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7059)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 278, 792)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2036)
[M::mem_pestat] mean and std.dev: (453.00, 444.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2658)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702912 sequences (100000165 bp) in 3.454 CPU sec, 3.587 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (81, 286567, 21, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 322, 1180)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3072)
[M::mem_pestat] mean and std.dev: (619.18, 588.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4018)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 228, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (249.62, 121.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 839)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (493, 703, 1682)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4060)
[M::mem_pestat] mean and std.dev: (1055.10, 740.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5249)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 279, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 596)
[M::mem_pestat] mean and std.dev: (246.43, 84.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 722)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703358 reads in 197.194 CPU sec, 6.282 real sec
sorting block 84, #reads = 1084423 mem = 536879639 peak = 1126559744
[M::process] read 702570 sequences (100000157 bp) in 2.587 CPU sec, 2.628 real sec...
[M::mem_process_seqs] Processed 703030 reads in 136.235 CPU sec, 4.294 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 286687, 41, 94)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 509, 1218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3194)
[M::mem_pestat] mean and std.dev: (595.61, 491.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4182)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 229, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (249.90, 120.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 839)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (408, 1465, 2896)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7872)
[M::mem_pestat] mean and std.dev: (1710.98, 1473.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10360)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 375, 765)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1801)
[M::mem_pestat] mean and std.dev: (458.82, 342.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2319)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 85, #reads = 1085376 mem = 536879950 peak = 1126559744
[M::process] read 702800 sequences (100000018 bp) in 3.419 CPU sec, 3.567 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 286432, 30, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 279, 575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1307)
[M::mem_pestat] mean and std.dev: (367.97, 299.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1673)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 230, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (252.07, 122.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 855)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (56, 511, 920)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2648)
[M::mem_pestat] mean and std.dev: (619.38, 619.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3512)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 378, 540)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1164)
[M::mem_pestat] mean and std.dev: (351.89, 174.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1476)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702912 reads in 201.141 CPU sec, 6.430 real sec
[M::mem_process_seqs] Processed 702570 reads in 138.452 CPU sec, 4.375 real sec
[M::process] read 702688 sequences (100000043 bp) in 2.638 CPU sec, 2.697 real sec...
sorting block 86, #reads = 1083810 mem = 536879526 peak = 1126559744
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 286953, 25, 81)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 327, 789)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1993)
[M::mem_pestat] mean and std.dev: (486.50, 396.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2595)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 230, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (252.93, 124.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 859)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (387, 735, 1980)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5166)
[M::mem_pestat] mean and std.dev: (736.33, 608.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6759)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 529, 1139)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3009)
[M::mem_pestat] mean and std.dev: (684.01, 657.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3944)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702480 sequences (100000216 bp) in 3.537 CPU sec, 3.693 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 286434, 26, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 494, 985)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2577)
[M::mem_pestat] mean and std.dev: (563.15, 416.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3373)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 229, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (253.13, 125.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 859)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 1320, 2246)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6400)
[M::mem_pestat] mean and std.dev: (1502.38, 1402.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8477)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 370, 942)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2408)
[M::mem_pestat] mean and std.dev: (508.29, 460.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3141)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702800 reads in 195.119 CPU sec, 6.223 real sec
[M::mem_process_seqs] Processed 702688 reads in 138.619 CPU sec, 4.384 real sec
[M::process] read 702468 sequences (100000190 bp) in 2.941 CPU sec, 3.027 real sec...
sorting block 87, #reads = 1083158 mem = 536879052 peak = 1126559744
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 286073, 27, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 406, 1062)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2754)
[M::mem_pestat] mean and std.dev: (617.35, 506.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3600)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 229, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684)
[M::mem_pestat] mean and std.dev: (253.42, 124.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 860)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (566, 1180, 3298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8762)
[M::mem_pestat] mean and std.dev: (1959.19, 1901.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11494)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (269, 426, 1218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3116)
[M::mem_pestat] mean and std.dev: (673.75, 596.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4065)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701894 sequences (100000083 bp) in 3.493 CPU sec, 3.646 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (81, 286581, 31, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (263, 374, 971)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2387)
[M::mem_pestat] mean and std.dev: (580.81, 400.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3095)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 229, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 686)
[M::mem_pestat] mean and std.dev: (253.57, 125.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 863)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (451, 750, 1490)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3568)
[M::mem_pestat] mean and std.dev: (1026.69, 905.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4649)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 377, 1084)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2866)
[M::mem_pestat] mean and std.dev: (623.95, 634.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3757)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702480 reads in 199.891 CPU sec, 6.369 real sec
sorting block 88, #reads = 1082863 mem = 536879378 peak = 1126559744
[M::mem_process_seqs] Processed 702468 reads in 139.692 CPU sec, 4.412 real sec
[M::process] read 709236 sequences (100000051 bp) in 2.797 CPU sec, 2.869 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 286516, 18, 85)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 605)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1507)
[M::mem_pestat] mean and std.dev: (337.65, 316.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1958)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 231, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (255.21, 125.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 872)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (515, 1590, 2192)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5546)
[M::mem_pestat] mean and std.dev: (1470.53, 1111.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7223)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 488, 1043)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2745)
[M::mem_pestat] mean and std.dev: (600.19, 570.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3596)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 89, #reads = 1082595 mem = 536877117 peak = 1142538240
[M::process] read 715248 sequences (100000276 bp) in 3.583 CPU sec, 3.712 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 288831, 42, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 290, 1033)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2775)
[M::mem_pestat] mean and std.dev: (523.40, 574.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3646)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 215, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 647)
[M::mem_pestat] mean and std.dev: (239.49, 119.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 814)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 555, 2013)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5697)
[M::mem_pestat] mean and std.dev: (871.10, 871.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7539)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 304, 1548)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4322)
[M::mem_pestat] mean and std.dev: (727.24, 914.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5709)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701894 reads in 210.819 CPU sec, 6.724 real sec
[M::mem_process_seqs] Processed 709236 reads in 152.221 CPU sec, 4.809 real sec
[M::process] read 713986 sequences (100000293 bp) in 2.883 CPU sec, 2.958 real sec...
sorting block 90, #reads = 1082284 mem = 536879456 peak = 1142538240
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 291814, 26, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 308, 1287)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3519)
[M::mem_pestat] mean and std.dev: (680.20, 679.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4635)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (140, 202, 290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 590)
[M::mem_pestat] mean and std.dev: (224.37, 110.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 740)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (323, 1233, 2377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6485)
[M::mem_pestat] mean and std.dev: (1575.00, 1530.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8539)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 350, 553)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1267)
[M::mem_pestat] mean and std.dev: (371.87, 246.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1624)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 712838 sequences (100000121 bp) in 3.233 CPU sec, 3.376 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 291093, 26, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 287, 655)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1651)
[M::mem_pestat] mean and std.dev: (334.31, 255.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2149)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (141, 205, 296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 606)
[M::mem_pestat] mean and std.dev: (228.45, 113.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 761)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (482, 1024, 1755)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4301)
[M::mem_pestat] mean and std.dev: (999.72, 607.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5574)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 279, 894)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2336)
[M::mem_pestat] mean and std.dev: (541.84, 558.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3057)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 715248 reads in 211.534 CPU sec, 6.747 real sec
[M::process] read 710804 sequences (100000100 bp) in 2.545 CPU sec, 2.578 real sec...
[M::mem_process_seqs] Processed 713986 reads in 146.558 CPU sec, 4.643 real sec
sorting block 91, #reads = 1086810 mem = 536877930 peak = 1142538240
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 291184, 32, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 257, 1463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3987)
[M::mem_pestat] mean and std.dev: (705.65, 806.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5249)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 208, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 622)
[M::mem_pestat] mean and std.dev: (232.30, 116.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 782)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (74, 189, 1117)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3203)
[M::mem_pestat] mean and std.dev: (614.65, 765.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4246)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 235, 403)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 851)
[M::mem_pestat] mean and std.dev: (243.24, 120.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1075)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 709984 sequences (100000084 bp) in 3.526 CPU sec, 3.676 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 290279, 34, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 343, 1225)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3315)
[M::mem_pestat] mean and std.dev: (604.47, 638.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4360)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 212, 310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 640)
[M::mem_pestat] mean and std.dev: (237.25, 119.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 805)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (495, 1095, 3726)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10188)
[M::mem_pestat] mean and std.dev: (2050.82, 2202.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13419)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 277, 752)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1832)
[M::mem_pestat] mean and std.dev: (371.90, 286.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2372)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 712838 reads in 200.239 CPU sec, 6.358 real sec
[M::process] read 709152 sequences (100000092 bp) in 2.752 CPU sec, 2.768 real sec...
[M::mem_process_seqs] Processed 710804 reads in 135.672 CPU sec, 4.279 real sec
sorting block 92, #reads = 1089442 mem = 536879819 peak = 1142538240
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 290114, 28, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 306, 646)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1588)
[M::mem_pestat] mean and std.dev: (384.77, 279.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2059)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 214, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 644)
[M::mem_pestat] mean and std.dev: (238.94, 120.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 810)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 599, 966)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2446)
[M::mem_pestat] mean and std.dev: (478.88, 418.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3186)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 277, 761)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1863)
[M::mem_pestat] mean and std.dev: (386.74, 332.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2414)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 93, #reads = 1089873 mem = 536884064 peak = 1142538240
[M::process] read 708530 sequences (100000113 bp) in 2.897 CPU sec, 3.035 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 288971, 35, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 322, 1416)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3866)
[M::mem_pestat] mean and std.dev: (669.14, 850.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5091)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 215, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 651)
[M::mem_pestat] mean and std.dev: (240.83, 121.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 819)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (450, 848, 1819)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4557)
[M::mem_pestat] mean and std.dev: (1169.71, 1032.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5926)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 473, 1054)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2758)
[M::mem_pestat] mean and std.dev: (598.77, 554.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3610)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708382 sequences (100000213 bp) in 2.308 CPU sec, 2.308 real sec...
[M::mem_process_seqs] Processed 709984 reads in 194.368 CPU sec, 6.173 real sec
[M::mem_process_seqs] Processed 709152 reads in 136.444 CPU sec, 4.319 real sec
sorting block 94, #reads = 1089304 mem = 536882124 peak = 1142538240
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 288797, 34, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 298, 675)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1611)
[M::mem_pestat] mean and std.dev: (355.12, 301.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2079)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 216, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 657)
[M::mem_pestat] mean and std.dev: (242.37, 122.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 827)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (292, 785, 1781)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4759)
[M::mem_pestat] mean and std.dev: (924.81, 681.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6248)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 412, 621)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1391)
[M::mem_pestat] mean and std.dev: (450.18, 303.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1776)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708126 sequences (100000163 bp) in 3.415 CPU sec, 3.539 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 289679, 36, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 388, 1218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3324)
[M::mem_pestat] mean and std.dev: (661.59, 688.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4377)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 217, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 658)
[M::mem_pestat] mean and std.dev: (242.82, 122.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 828)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (468, 789, 2823)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7533)
[M::mem_pestat] mean and std.dev: (1295.82, 1086.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9888)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 300, 1180)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3092)
[M::mem_pestat] mean and std.dev: (565.38, 494.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4048)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707314 sequences (100000138 bp) in 2.398 CPU sec, 2.401 real sec...
[M::mem_process_seqs] Processed 708530 reads in 195.857 CPU sec, 6.197 real sec
[M::mem_process_seqs] Processed 708382 reads in 136.920 CPU sec, 4.346 real sec
sorting block 95, #reads = 1086860 mem = 536880149 peak = 1142538240
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 289422, 16, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 310, 1042)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2742)
[M::mem_pestat] mean and std.dev: (615.42, 668.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3592)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 218, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (243.80, 123.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 832)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (359, 848, 2362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6368)
[M::mem_pestat] mean and std.dev: (957.64, 795.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8371)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 256, 647)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1565)
[M::mem_pestat] mean and std.dev: (425.41, 358.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2024)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706924 sequences (100000150 bp) in 3.436 CPU sec, 3.569 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 288827, 39, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 325, 648)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1638)
[M::mem_pestat] mean and std.dev: (419.35, 358.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2133)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 219, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (245.46, 123.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 841)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (422, 620, 1069)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2363)
[M::mem_pestat] mean and std.dev: (646.09, 471.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3010)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 252, 882)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2252)
[M::mem_pestat] mean and std.dev: (418.90, 396.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2937)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 708126 reads in 198.434 CPU sec, 6.305 real sec
[M::process] read 707374 sequences (100000031 bp) in 2.662 CPU sec, 2.690 real sec...
[M::mem_process_seqs] Processed 707314 reads in 140.027 CPU sec, 4.427 real sec
sorting block 96, #reads = 1087946 mem = 536880142 peak = 1142538240
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 288678, 24, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 286, 482)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1092)
[M::mem_pestat] mean and std.dev: (326.84, 210.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1397)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 221, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (246.62, 124.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 845)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 487, 993)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2559)
[M::mem_pestat] mean and std.dev: (545.73, 420.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3342)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 364, 1112)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2960)
[M::mem_pestat] mean and std.dev: (683.67, 671.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3884)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 97, #reads = 1086585 mem = 536880288 peak = 1142538240
[M::process] read 706378 sequences (100000198 bp) in 3.007 CPU sec, 3.110 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 288918, 37, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 486, 848)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2246)
[M::mem_pestat] mean and std.dev: (471.81, 338.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2945)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 220, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (246.39, 124.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 845)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (612, 819, 2159)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5253)
[M::mem_pestat] mean and std.dev: (1226.68, 1140.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6800)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 319, 628)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1478)
[M::mem_pestat] mean and std.dev: (369.64, 286.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1903)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706924 reads in 204.606 CPU sec, 6.540 real sec
[M::process] read 706046 sequences (100000298 bp) in 2.710 CPU sec, 2.735 real sec...
[M::mem_process_seqs] Processed 707374 reads in 141.663 CPU sec, 4.484 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 288516, 31, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 309, 689)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1679)
[M::mem_pestat] mean and std.dev: (366.47, 259.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2174)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 223, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 676)
[M::mem_pestat] mean and std.dev: (248.74, 125.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 851)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (363, 686, 1700)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4374)
[M::mem_pestat] mean and std.dev: (761.15, 666.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5711)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 325, 572)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1290)
[M::mem_pestat] mean and std.dev: (331.83, 174.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1649)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 98, #reads = 1086296 mem = 536880347 peak = 1142538240
[M::process] read 705654 sequences (100000034 bp) in 3.749 CPU sec, 3.934 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 288195, 50, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 289, 1166)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3106)
[M::mem_pestat] mean and std.dev: (579.04, 642.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4076)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 222, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 670)
[M::mem_pestat] mean and std.dev: (247.39, 123.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 843)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 974, 2578)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7354)
[M::mem_pestat] mean and std.dev: (1391.60, 1290.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9742)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 390, 941)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2445)
[M::mem_pestat] mean and std.dev: (574.37, 515.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3197)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706378 reads in 206.537 CPU sec, 6.594 real sec
[M::mem_process_seqs] Processed 706046 reads in 143.964 CPU sec, 4.545 real sec
[M::process] read 705224 sequences (100000147 bp) in 2.841 CPU sec, 2.918 real sec...
sorting block 99, #reads = 1086662 mem = 536880509 peak = 1142538240
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (79, 287915, 31, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 411, 1226)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3228)
[M::mem_pestat] mean and std.dev: (599.70, 587.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4229)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 224, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 676)
[M::mem_pestat] mean and std.dev: (249.03, 125.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 851)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (520, 686, 2148)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5404)
[M::mem_pestat] mean and std.dev: (1241.71, 1005.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7032)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 357, 947)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2447)
[M::mem_pestat] mean and std.dev: (515.49, 536.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3197)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705182 sequences (100000067 bp) in 3.591 CPU sec, 3.756 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 287403, 31, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 343, 1003)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2597)
[M::mem_pestat] mean and std.dev: (567.53, 595.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3394)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 677)
[M::mem_pestat] mean and std.dev: (249.30, 124.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 852)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (454, 712, 1313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3031)
[M::mem_pestat] mean and std.dev: (875.33, 757.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3903)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 313, 816)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1998)
[M::mem_pestat] mean and std.dev: (493.41, 398.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2589)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705654 reads in 207.349 CPU sec, 6.606 real sec
[M::mem_process_seqs] Processed 705224 reads in 144.461 CPU sec, 4.554 real sec
[M::process] read 704568 sequences (100000274 bp) in 2.742 CPU sec, 2.791 real sec...
sorting block 100, #reads = 1083988 mem = 536879588 peak = 1142538240
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (85, 287860, 43, 85)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 235, 769)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1915)
[M::mem_pestat] mean and std.dev: (302.68, 272.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2488)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 225, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 677)
[M::mem_pestat] mean and std.dev: (249.53, 124.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 852)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (253, 634, 1804)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4906)
[M::mem_pestat] mean and std.dev: (1120.26, 1203.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6457)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 410, 982)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2540)
[M::mem_pestat] mean and std.dev: (602.48, 548.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3319)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704324 sequences (100000054 bp) in 3.581 CPU sec, 3.729 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 287618, 38, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 355, 764)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1918)
[M::mem_pestat] mean and std.dev: (492.01, 445.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2495)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 225, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 678)
[M::mem_pestat] mean and std.dev: (250.33, 125.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 853)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 1252, 2120)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5858)
[M::mem_pestat] mean and std.dev: (1256.06, 1340.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7727)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 370, 1140)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3010)
[M::mem_pestat] mean and std.dev: (593.29, 630.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3945)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705182 reads in 207.175 CPU sec, 6.603 real sec
sorting block 101, #reads = 1083774 mem = 536876610 peak = 1142538240
[M::process] read 704436 sequences (100000036 bp) in 2.577 CPU sec, 2.626 real sec...
[M::mem_process_seqs] Processed 704568 reads in 143.657 CPU sec, 4.541 real sec
sorting block 102, #reads = 1084056 mem = 536885718 peak = 1144717312
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 287470, 22, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 322, 664)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1578)
[M::mem_pestat] mean and std.dev: (365.15, 271.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2035)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 225, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 675)
[M::mem_pestat] mean and std.dev: (249.86, 124.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 849)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 1255, 1954)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5562)
[M::mem_pestat] mean and std.dev: (1056.05, 1024.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7366)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 443, 1054)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2676)
[M::mem_pestat] mean and std.dev: (606.09, 580.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3487)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704606 sequences (100000109 bp) in 2.921 CPU sec, 3.037 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 287725, 35, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (278, 390, 986)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2402)
[M::mem_pestat] mean and std.dev: (557.68, 445.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3110)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 225, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 672)
[M::mem_pestat] mean and std.dev: (249.32, 124.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 845)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 416, 981)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2547)
[M::mem_pestat] mean and std.dev: (462.58, 396.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3330)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 498, 1312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3484)
[M::mem_pestat] mean and std.dev: (672.60, 580.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4570)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703760 sequences (100000141 bp) in 2.502 CPU sec, 2.508 real sec...
[M::mem_process_seqs] Processed 704324 reads in 206.924 CPU sec, 6.579 real sec
[M::mem_process_seqs] Processed 704436 reads in 143.024 CPU sec, 4.541 real sec
sorting block 103, #reads = 1084721 mem = 536880161 peak = 1144717312
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 287711, 29, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 244, 520)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1184)
[M::mem_pestat] mean and std.dev: (312.66, 211.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1516)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 225, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 677)
[M::mem_pestat] mean and std.dev: (249.85, 124.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 852)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 432, 1529)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4227)
[M::mem_pestat] mean and std.dev: (673.93, 623.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5576)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 364, 907)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2371)
[M::mem_pestat] mean and std.dev: (574.33, 502.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3103)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703878 sequences (100000011 bp) in 3.417 CPU sec, 3.605 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 287098, 27, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 620, 1534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4164)
[M::mem_pestat] mean and std.dev: (1013.11, 1013.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5479)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 226, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 681)
[M::mem_pestat] mean and std.dev: (251.64, 125.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 857)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (395, 571, 1294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3092)
[M::mem_pestat] mean and std.dev: (962.26, 920.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4644)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 429, 618)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1392)
[M::mem_pestat] mean and std.dev: (408.45, 233.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1779)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704606 reads in 207.551 CPU sec, 6.783 real sec
[M::process] read 703876 sequences (100000162 bp) in 2.663 CPU sec, 2.694 real sec...
[M::mem_process_seqs] Processed 703760 reads in 145.753 CPU sec, 4.621 real sec
sorting block 104, #reads = 1084021 mem = 536878069 peak = 1144717312
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 286896, 48, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 275, 535)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1281)
[M::mem_pestat] mean and std.dev: (252.72, 159.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1654)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 226, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 678)
[M::mem_pestat] mean and std.dev: (250.61, 124.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 853)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (514, 1167, 2547)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6613)
[M::mem_pestat] mean and std.dev: (1208.79, 1174.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8646)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 354, 1630)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4444)
[M::mem_pestat] mean and std.dev: (840.96, 962.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5851)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703718 sequences (100000166 bp) in 3.809 CPU sec, 3.972 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 286895, 35, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 297, 1123)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2887)
[M::mem_pestat] mean and std.dev: (636.59, 674.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3769)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 226, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 675)
[M::mem_pestat] mean and std.dev: (250.12, 124.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 849)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (310, 916, 2264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6172)
[M::mem_pestat] mean and std.dev: (1350.53, 1408.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8126)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 408, 594)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1356)
[M::mem_pestat] mean and std.dev: (365.30, 246.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1737)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703878 reads in 211.345 CPU sec, 6.725 real sec
sorting block 105, #reads = 1082484 mem = 536881580 peak = 1144717312
[M::process] read 703174 sequences (100000294 bp) in 2.727 CPU sec, 2.770 real sec...
[M::mem_process_seqs] Processed 703876 reads in 148.231 CPU sec, 4.681 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 287343, 31, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 294, 1325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3587)
[M::mem_pestat] mean and std.dev: (541.05, 580.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4718)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 227, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 681)
[M::mem_pestat] mean and std.dev: (251.06, 124.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 857)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (486, 659, 2302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5934)
[M::mem_pestat] mean and std.dev: (1203.83, 1232.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7750)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 342, 816)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2078)
[M::mem_pestat] mean and std.dev: (486.54, 406.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2709)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 106, #reads = 1081985 mem = 536876770 peak = 1144717312
[M::process] read 703550 sequences (100000173 bp) in 3.364 CPU sec, 3.514 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 286773, 29, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 240, 587)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1423)
[M::mem_pestat] mean and std.dev: (319.65, 272.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1841)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (251.68, 124.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (374, 613, 2168)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5756)
[M::mem_pestat] mean and std.dev: (1041.54, 1114.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7550)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 394, 845)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2029)
[M::mem_pestat] mean and std.dev: (477.48, 365.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2621)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703718 reads in 210.894 CPU sec, 6.734 real sec
[M::process] read 702978 sequences (100000114 bp) in 2.744 CPU sec, 2.792 real sec...
[M::mem_process_seqs] Processed 703174 reads in 148.077 CPU sec, 4.677 real sec
sorting block 107, #reads = 1081732 mem = 536880265 peak = 1144717312
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 287080, 37, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 447, 1323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3525)
[M::mem_pestat] mean and std.dev: (791.43, 765.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4626)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (251.44, 124.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (413, 1069, 2357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6245)
[M::mem_pestat] mean and std.dev: (1202.39, 1166.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8189)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 444, 1005)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2525)
[M::mem_pestat] mean and std.dev: (626.62, 563.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3285)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703616 sequences (100000265 bp) in 3.757 CPU sec, 3.903 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 286871, 34, 85)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 272, 701)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1703)
[M::mem_pestat] mean and std.dev: (433.93, 370.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2204)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 228, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (251.89, 124.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 855)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 572, 1123)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3029)
[M::mem_pestat] mean and std.dev: (773.91, 725.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3982)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 364, 1001)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2611)
[M::mem_pestat] mean and std.dev: (612.24, 568.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3416)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703550 reads in 209.657 CPU sec, 6.692 real sec
[M::mem_process_seqs] Processed 702978 reads in 147.173 CPU sec, 4.653 real sec
[M::process] read 703098 sequences (100000138 bp) in 2.970 CPU sec, 3.045 real sec...
sorting block 108, #reads = 1082206 mem = 536881215 peak = 1144717312
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 287333, 28, 93)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (131, 258, 532)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1334)
[M::mem_pestat] mean and std.dev: (287.10, 219.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1735)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (251.30, 124.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (398, 604, 2581)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6947)
[M::mem_pestat] mean and std.dev: (1291.60, 1452.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9130)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 295, 876)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2240)
[M::mem_pestat] mean and std.dev: (513.02, 441.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2922)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702614 sequences (100000095 bp) in 3.784 CPU sec, 3.982 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 286731, 47, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 478, 1321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3583)
[M::mem_pestat] mean and std.dev: (755.92, 766.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4714)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 227, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (252.50, 125.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 859)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (604, 807, 1249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2539)
[M::mem_pestat] mean and std.dev: (673.71, 343.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3184)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 311, 570)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1244)
[M::mem_pestat] mean and std.dev: (376.93, 259.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1581)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703616 reads in 204.900 CPU sec, 6.531 real sec
sorting block 109, #reads = 1082489 mem = 536879805 peak = 1144717312
[M::mem_process_seqs] Processed 703098 reads in 142.580 CPU sec, 4.506 real sec
[M::process] read 702652 sequences (100000081 bp) in 2.942 CPU sec, 3.008 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 286550, 32, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 437, 715)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1731)
[M::mem_pestat] mean and std.dev: (465.89, 363.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2239)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 228, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (252.87, 125.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 859)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (588, 880, 1196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2412)
[M::mem_pestat] mean and std.dev: (856.10, 523.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3020)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 387, 829)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2069)
[M::mem_pestat] mean and std.dev: (584.32, 570.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2868)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 110, #reads = 1082472 mem = 536880354 peak = 1144717312
[M::process] read 705638 sequences (100000059 bp) in 3.510 CPU sec, 3.651 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 286846, 30, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 430, 1560)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4186)
[M::mem_pestat] mean and std.dev: (915.97, 1066.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5499)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 229, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 686)
[M::mem_pestat] mean and std.dev: (253.55, 126.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 863)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (706, 1009, 1572)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3304)
[M::mem_pestat] mean and std.dev: (1008.81, 741.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4170)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 360, 599)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1345)
[M::mem_pestat] mean and std.dev: (406.75, 311.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1718)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702614 reads in 210.283 CPU sec, 6.711 real sec
[M::mem_process_seqs] Processed 702652 reads in 148.803 CPU sec, 4.701 real sec
[M::process] read 718376 sequences (100000262 bp) in 2.889 CPU sec, 2.960 real sec...
sorting block 111, #reads = 1081246 mem = 536878279 peak = 1144717312
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 287765, 30, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 318, 874)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2318)
[M::mem_pestat] mean and std.dev: (560.70, 578.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3040)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 223, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 670)
[M::mem_pestat] mean and std.dev: (247.50, 123.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 843)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (432, 851, 1107)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2457)
[M::mem_pestat] mean and std.dev: (861.48, 655.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3482)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 307, 643)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1521)
[M::mem_pestat] mean and std.dev: (380.11, 285.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1960)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 716858 sequences (100000061 bp) in 3.172 CPU sec, 3.339 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 292575, 31, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 236, 547)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1325)
[M::mem_pestat] mean and std.dev: (300.60, 253.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1714)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 197, 283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 575)
[M::mem_pestat] mean and std.dev: (219.00, 106.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 721)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (316, 870, 1155)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2833)
[M::mem_pestat] mean and std.dev: (794.07, 559.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3672)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 381, 805)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1927)
[M::mem_pestat] mean and std.dev: (463.45, 372.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2488)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717014 sequences (100000301 bp) in 2.060 CPU sec, 2.056 real sec...
[M::mem_process_seqs] Processed 705638 reads in 222.254 CPU sec, 7.091 real sec
[M::mem_process_seqs] Processed 718376 reads in 156.206 CPU sec, 4.974 real sec
sorting block 112, #reads = 1080648 mem = 536881518 peak = 1144717312
[M::process] read 715760 sequences (100000166 bp) in 3.596 CPU sec, 3.725 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 292138, 26, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 242, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 955)
[M::mem_pestat] mean and std.dev: (246.18, 150.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1215)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 199, 287)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 585)
[M::mem_pestat] mean and std.dev: (222.16, 109.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 734)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (350, 808, 1304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3212)
[M::mem_pestat] mean and std.dev: (855.88, 613.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4166)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 280, 1383)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3779)
[M::mem_pestat] mean and std.dev: (629.87, 551.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4977)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 714032 sequences (100000005 bp) in 2.702 CPU sec, 2.709 real sec...
[M::mem_process_seqs] Processed 717014 reads in 132.202 CPU sec, 4.159 real sec
sorting block 113, #reads = 1089230 mem = 536877155 peak = 1144717312
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 291986, 30, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 411, 813)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1983)
[M::mem_pestat] mean and std.dev: (544.88, 496.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2568)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 199, 287)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 585)
[M::mem_pestat] mean and std.dev: (221.94, 108.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 734)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (313, 1042, 1985)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5329)
[M::mem_pestat] mean and std.dev: (1200.43, 1052.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7001)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 510, 1330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3544)
[M::mem_pestat] mean and std.dev: (841.52, 837.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4651)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 291577, 26, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 360, 901)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2287)
[M::mem_pestat] mean and std.dev: (466.00, 413.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2980)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (140, 202, 291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 593)
[M::mem_pestat] mean and std.dev: (224.61, 110.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 744)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (403, 530, 831)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1687)
[M::mem_pestat] mean and std.dev: (533.12, 314.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2115)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 290, 763)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1979)
[M::mem_pestat] mean and std.dev: (329.00, 317.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2587)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 716858 reads in 354.961 CPU sec, 11.262 real sec
[M::process] read 713090 sequences (100000015 bp) in 2.667 CPU sec, 2.671 real sec...
[M::mem_process_seqs] Processed 715760 reads in 185.248 CPU sec, 5.919 real sec
sorting block 114, #reads = 1087717 mem = 536876983 peak = 1144717312
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 291202, 33, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 356, 531)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1247)
[M::mem_pestat] mean and std.dev: (311.69, 218.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1605)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 206, 298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 610)
[M::mem_pestat] mean and std.dev: (229.38, 113.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 766)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 324, 1133)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2929)
[M::mem_pestat] mean and std.dev: (664.12, 613.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3827)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 344, 1040)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2668)
[M::mem_pestat] mean and std.dev: (544.91, 549.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3482)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 712020 sequences (100000129 bp) in 3.916 CPU sec, 4.082 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 290623, 34, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 318, 898)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2334)
[M::mem_pestat] mean and std.dev: (421.14, 414.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3052)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 207, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 616)
[M::mem_pestat] mean and std.dev: (230.54, 114.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 774)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (373, 1055, 1554)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3916)
[M::mem_pestat] mean and std.dev: (1039.47, 800.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5097)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (270, 405, 1888)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5124)
[M::mem_pestat] mean and std.dev: (1245.17, 1309.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6742)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 714032 reads in 224.994 CPU sec, 7.140 real sec
[M::process] read 711592 sequences (100000072 bp) in 2.520 CPU sec, 2.526 real sec...
sorting block 115, #reads = 1085032 mem = 536877446 peak = 1144717312
[M::mem_process_seqs] Processed 713090 reads in 152.435 CPU sec, 4.834 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 290488, 21, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 374, 726)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1688)
[M::mem_pestat] mean and std.dev: (498.31, 376.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2169)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 209, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 629)
[M::mem_pestat] mean and std.dev: (234.07, 116.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 791)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (316, 538, 1368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3472)
[M::mem_pestat] mean and std.dev: (542.61, 513.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4524)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 385, 536)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1254)
[M::mem_pestat] mean and std.dev: (365.75, 234.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1613)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 116, #reads = 1085649 mem = 536887411 peak = 1144717312
[M::process] read 711558 sequences (100000289 bp) in 3.376 CPU sec, 3.534 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 290523, 34, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 375, 1456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3980)
[M::mem_pestat] mean and std.dev: (749.02, 880.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5242)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 210, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 630)
[M::mem_pestat] mean and std.dev: (234.89, 117.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 792)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (390, 1205, 2542)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6846)
[M::mem_pestat] mean and std.dev: (1709.56, 1518.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8998)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 427, 933)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2343)
[M::mem_pestat] mean and std.dev: (594.46, 526.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3048)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 710300 sequences (100000109 bp) in 2.517 CPU sec, 2.527 real sec...
[M::mem_process_seqs] Processed 712020 reads in 221.643 CPU sec, 7.043 real sec
[M::mem_process_seqs] Processed 711592 reads in 151.533 CPU sec, 4.811 real sec
sorting block 117, #reads = 1085238 mem = 536881671 peak = 1144717312
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 290446, 26, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 425, 1170)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3036)
[M::mem_pestat] mean and std.dev: (725.47, 761.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3969)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 210, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 630)
[M::mem_pestat] mean and std.dev: (234.86, 117.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 792)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (771, 906, 1627)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3339)
[M::mem_pestat] mean and std.dev: (1138.67, 756.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4195)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 284, 521)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1211)
[M::mem_pestat] mean and std.dev: (269.20, 164.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1556)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 709894 sequences (100000164 bp) in 3.648 CPU sec, 3.818 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 289856, 22, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 672, 1373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3657)
[M::mem_pestat] mean and std.dev: (886.46, 780.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4799)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 213, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 644)
[M::mem_pestat] mean and std.dev: (238.59, 119.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 810)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (298, 595, 952)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2260)
[M::mem_pestat] mean and std.dev: (625.48, 425.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2914)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 250, 716)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1782)
[M::mem_pestat] mean and std.dev: (354.72, 288.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2315)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 711558 reads in 216.022 CPU sec, 6.846 real sec
[M::process] read 710186 sequences (100000183 bp) in 2.698 CPU sec, 2.704 real sec...
[M::mem_process_seqs] Processed 710300 reads in 148.010 CPU sec, 4.682 real sec
sorting block 118, #reads = 1085158 mem = 536883174 peak = 1144717312
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 289882, 15, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (259, 355, 1694)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4564)
[M::mem_pestat] mean and std.dev: (778.12, 770.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5999)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 215, 314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 650)
[M::mem_pestat] mean and std.dev: (240.09, 120.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 818)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (371, 929, 1350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3308)
[M::mem_pestat] mean and std.dev: (946.20, 660.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4287)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 242, 579)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1393)
[M::mem_pestat] mean and std.dev: (312.67, 215.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1800)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 709548 sequences (100000295 bp) in 3.752 CPU sec, 3.967 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 289681, 38, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 403, 1131)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2961)
[M::mem_pestat] mean and std.dev: (536.13, 466.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3876)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 214, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 644)
[M::mem_pestat] mean and std.dev: (238.76, 119.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 810)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (73, 464, 579)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1591)
[M::mem_pestat] mean and std.dev: (359.44, 279.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2097)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 373, 955)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2485)
[M::mem_pestat] mean and std.dev: (455.66, 427.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3250)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 709894 reads in 215.379 CPU sec, 6.835 real sec
[M::process] read 709420 sequences (100000190 bp) in 2.709 CPU sec, 2.728 real sec...
[M::mem_process_seqs] Processed 710186 reads in 150.392 CPU sec, 4.756 real sec
sorting block 119, #reads = 1085825 mem = 536878060 peak = 1144717312
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 289778, 24, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 583, 1586)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4302)
[M::mem_pestat] mean and std.dev: (1005.60, 975.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5660)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 215, 314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 650)
[M::mem_pestat] mean and std.dev: (240.24, 120.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 818)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 494, 1390)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3812)
[M::mem_pestat] mean and std.dev: (733.13, 700.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5023)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 454, 1103)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2821)
[M::mem_pestat] mean and std.dev: (729.48, 693.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3680)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 120, #reads = 1085461 mem = 536878987 peak = 1144717312
[M::process] read 708348 sequences (100000178 bp) in 3.518 CPU sec, 3.641 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 289907, 46, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 420, 851)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2097)
[M::mem_pestat] mean and std.dev: (449.94, 372.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2720)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 216, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 651)
[M::mem_pestat] mean and std.dev: (240.84, 120.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 819)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (268, 474, 966)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2362)
[M::mem_pestat] mean and std.dev: (508.54, 334.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3060)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 289, 874)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2256)
[M::mem_pestat] mean and std.dev: (482.47, 472.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2947)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 709548 reads in 211.882 CPU sec, 6.735 real sec
[M::process] read 708160 sequences (100000022 bp) in 2.486 CPU sec, 2.496 real sec...
[M::mem_process_seqs] Processed 709420 reads in 146.130 CPU sec, 4.632 real sec
sorting block 121, #reads = 1085964 mem = 536880237 peak = 1144717312
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 289165, 30, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 364, 595)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1389)
[M::mem_pestat] mean and std.dev: (399.30, 243.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1786)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 218, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (243.48, 122.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 832)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (657, 1998, 3485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9141)
[M::mem_pestat] mean and std.dev: (2369.80, 2238.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11969)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 356, 834)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2074)
[M::mem_pestat] mean and std.dev: (449.38, 366.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2694)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707464 sequences (100000063 bp) in 3.152 CPU sec, 3.274 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 289076, 22, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 285, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 994)
[M::mem_pestat] mean and std.dev: (295.92, 175.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1268)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 218, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (244.04, 122.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 836)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 368, 701)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1697)
[M::mem_pestat] mean and std.dev: (427.80, 371.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2195)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 319, 1037)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2779)
[M::mem_pestat] mean and std.dev: (604.14, 613.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3650)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706388 sequences (100000211 bp) in 2.568 CPU sec, 2.576 real sec...
[M::mem_process_seqs] Processed 708348 reads in 207.549 CPU sec, 6.586 real sec
[M::mem_process_seqs] Processed 708160 reads in 143.244 CPU sec, 4.557 real sec
sorting block 122, #reads = 1085208 mem = 536884615 peak = 1144717312
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 288416, 49, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 383, 1251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3405)
[M::mem_pestat] mean and std.dev: (716.80, 830.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4482)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 220, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (245.73, 123.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 845)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (344, 854, 1408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3536)
[M::mem_pestat] mean and std.dev: (807.22, 603.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4600)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 312, 1081)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2829)
[M::mem_pestat] mean and std.dev: (570.20, 591.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3703)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705780 sequences (100000273 bp) in 4.009 CPU sec, 4.155 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 288177, 36, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 432, 1639)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4523)
[M::mem_pestat] mean and std.dev: (828.41, 879.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5965)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 221, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 669)
[M::mem_pestat] mean and std.dev: (246.64, 123.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 842)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (510, 780, 1301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2883)
[M::mem_pestat] mean and std.dev: (790.36, 562.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3674)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 385, 1100)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2920)
[M::mem_pestat] mean and std.dev: (624.79, 638.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3830)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707464 reads in 215.018 CPU sec, 6.838 real sec
[M::process] read 705356 sequences (100000258 bp) in 2.241 CPU sec, 2.242 real sec...
sorting block 123, #reads = 1084486 mem = 536878014 peak = 1144717312
[M::mem_process_seqs] Processed 706388 reads in 149.796 CPU sec, 4.744 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 288146, 45, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 267, 659)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1609)
[M::mem_pestat] mean and std.dev: (389.26, 341.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2084)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 223, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 670)
[M::mem_pestat] mean and std.dev: (247.55, 123.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 843)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (313, 689, 1960)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5254)
[M::mem_pestat] mean and std.dev: (1128.60, 1184.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6901)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (292, 371, 1457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3787)
[M::mem_pestat] mean and std.dev: (815.23, 846.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4952)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705612 sequences (100000020 bp) in 3.799 CPU sec, 3.969 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 287908, 46, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 244, 542)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1334)
[M::mem_pestat] mean and std.dev: (375.18, 327.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1730)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 223, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 673)
[M::mem_pestat] mean and std.dev: (247.78, 123.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 847)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (258, 565, 800)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1884)
[M::mem_pestat] mean and std.dev: (546.48, 352.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2426)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 337, 1263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3359)
[M::mem_pestat] mean and std.dev: (560.76, 529.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4407)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705780 reads in 212.883 CPU sec, 6.746 real sec
[M::process] read 704950 sequences (100000272 bp) in 2.557 CPU sec, 2.561 real sec...
sorting block 124, #reads = 1083478 mem = 536878743 peak = 1144717312
[M::mem_process_seqs] Processed 705356 reads in 147.283 CPU sec, 4.660 real sec
sorting block 125, #reads = 1082459 mem = 536878228 peak = 1151565824
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 287849, 44, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 342, 764)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1854)
[M::mem_pestat] mean and std.dev: (504.59, 484.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2441)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 223, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 673)
[M::mem_pestat] mean and std.dev: (248.28, 124.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 847)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (491, 963, 2393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6197)
[M::mem_pestat] mean and std.dev: (1600.40, 1635.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8141)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 301, 709)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1805)
[M::mem_pestat] mean and std.dev: (406.15, 336.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2353)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704546 sequences (100000173 bp) in 3.424 CPU sec, 3.563 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 287422, 17, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 233, 552)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1338)
[M::mem_pestat] mean and std.dev: (333.26, 287.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1731)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (248.89, 124.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 848)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 495, 1684)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4642)
[M::mem_pestat] mean and std.dev: (791.00, 715.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6121)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 384, 775)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1977)
[M::mem_pestat] mean and std.dev: (446.96, 388.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2578)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705612 reads in 210.731 CPU sec, 6.697 real sec
[M::process] read 704332 sequences (100000193 bp) in 2.559 CPU sec, 2.572 real sec...
[M::mem_process_seqs] Processed 704950 reads in 144.435 CPU sec, 4.565 real sec
sorting block 126, #reads = 1082595 mem = 536883552 peak = 1151565824
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 287651, 14, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 325, 853)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2255)
[M::mem_pestat] mean and std.dev: (569.23, 609.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3006)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 225, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (249.51, 124.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 848)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (503, 1436, 3966)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10892)
[M::mem_pestat] mean and std.dev: (2308.64, 2600.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14355)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 375, 998)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2540)
[M::mem_pestat] mean and std.dev: (618.75, 565.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3311)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704220 sequences (100000219 bp) in 3.467 CPU sec, 3.622 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 287482, 34, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 345, 1346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3680)
[M::mem_pestat] mean and std.dev: (733.36, 900.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4847)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 226, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 678)
[M::mem_pestat] mean and std.dev: (250.27, 124.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 853)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 657, 1314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3414)
[M::mem_pestat] mean and std.dev: (755.63, 721.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4464)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 581, 986)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2498)
[M::mem_pestat] mean and std.dev: (618.52, 496.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3254)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704546 reads in 208.996 CPU sec, 6.658 real sec
[M::process] read 704476 sequences (100000038 bp) in 2.753 CPU sec, 2.806 real sec...
[M::mem_process_seqs] Processed 704332 reads in 143.038 CPU sec, 4.518 real sec
sorting block 127, #reads = 1082709 mem = 536878624 peak = 1151565824
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 287595, 31, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 249, 546)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1272)
[M::mem_pestat] mean and std.dev: (331.98, 264.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1635)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 226, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 675)
[M::mem_pestat] mean and std.dev: (250.17, 124.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 849)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (389, 793, 1323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3191)
[M::mem_pestat] mean and std.dev: (831.39, 719.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4125)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 348, 976)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2586)
[M::mem_pestat] mean and std.dev: (517.33, 514.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3391)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703382 sequences (100000144 bp) in 3.239 CPU sec, 3.419 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (96, 287309, 31, 89)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 403, 761)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1901)
[M::mem_pestat] mean and std.dev: (462.74, 335.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2471)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 225, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 672)
[M::mem_pestat] mean and std.dev: (249.14, 123.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 845)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 599, 1690)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4720)
[M::mem_pestat] mean and std.dev: (920.07, 1050.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6235)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 429, 885)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2219)
[M::mem_pestat] mean and std.dev: (488.35, 393.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2886)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704220 reads in 211.855 CPU sec, 6.759 real sec
[M::process] read 702948 sequences (100000185 bp) in 2.440 CPU sec, 2.449 real sec...
sorting block 128, #reads = 1082337 mem = 536878759 peak = 1151565824
[M::mem_process_seqs] Processed 704476 reads in 146.759 CPU sec, 4.649 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 287253, 41, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 288, 908)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2350)
[M::mem_pestat] mean and std.dev: (477.50, 460.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3071)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (252.55, 126.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 862)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (355, 1088, 2826)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7768)
[M::mem_pestat] mean and std.dev: (1792.56, 1905.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10239)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 415, 1097)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2849)
[M::mem_pestat] mean and std.dev: (613.42, 582.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3725)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 129, #reads = 1082527 mem = 536878057 peak = 1151565824
[M::process] read 702880 sequences (100000198 bp) in 3.337 CPU sec, 3.513 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 286627, 40, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 283, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 987)
[M::mem_pestat] mean and std.dev: (325.61, 211.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1248)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 228, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (252.73, 125.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 859)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (630, 1309, 3871)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10353)
[M::mem_pestat] mean and std.dev: (2223.60, 2357.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13594)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 372, 663)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1559)
[M::mem_pestat] mean and std.dev: (401.77, 281.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2007)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703382 reads in 207.440 CPU sec, 6.604 real sec
[M::process] read 703226 sequences (100000054 bp) in 2.348 CPU sec, 2.356 real sec...
[M::mem_process_seqs] Processed 702948 reads in 142.620 CPU sec, 4.519 real sec
sorting block 130, #reads = 1081754 mem = 536878070 peak = 1151565824
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 286834, 32, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 333, 1282)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3474)
[M::mem_pestat] mean and std.dev: (548.66, 593.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4570)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 228, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (252.62, 125.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 859)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 618, 1722)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4804)
[M::mem_pestat] mean and std.dev: (969.93, 1115.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6345)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 688, 1502)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4008)
[M::mem_pestat] mean and std.dev: (943.49, 804.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5261)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703952 sequences (100000036 bp) in 3.333 CPU sec, 3.528 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 286997, 23, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 430, 1214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3218)
[M::mem_pestat] mean and std.dev: (749.83, 696.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4220)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (252.97, 126.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 862)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 1754, 3964)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11410)
[M::mem_pestat] mean and std.dev: (2670.35, 2647.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 15133)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 442, 902)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2246)
[M::mem_pestat] mean and std.dev: (570.81, 519.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2918)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702880 reads in 206.082 CPU sec, 6.561 real sec
[M::mem_process_seqs] Processed 703226 reads in 142.784 CPU sec, 4.506 real sec
[M::process] read 704282 sequences (100000265 bp) in 2.958 CPU sec, 3.014 real sec...
sorting block 131, #reads = 1082751 mem = 536879179 peak = 1151565824
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 287272, 25, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 335, 924)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2410)
[M::mem_pestat] mean and std.dev: (574.21, 575.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3153)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 226, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 678)
[M::mem_pestat] mean and std.dev: (250.55, 124.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 853)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 1169, 3387)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9811)
[M::mem_pestat] mean and std.dev: (2267.08, 2576.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13023)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 444, 2409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6717)
[M::mem_pestat] mean and std.dev: (1143.89, 1446.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8871)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717548 sequences (100000243 bp) in 3.763 CPU sec, 3.960 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 287146, 30, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 345, 704)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1732)
[M::mem_pestat] mean and std.dev: (447.01, 378.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2246)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (249.20, 124.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 848)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (336, 1095, 1693)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4407)
[M::mem_pestat] mean and std.dev: (1035.57, 744.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5764)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 305, 845)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2111)
[M::mem_pestat] mean and std.dev: (523.40, 499.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2744)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703952 reads in 223.317 CPU sec, 7.149 real sec
sorting block 132, #reads = 1082818 mem = 536879023 peak = 1151565824
[M::mem_process_seqs] Processed 704282 reads in 164.975 CPU sec, 5.211 real sec
[M::process] read 714434 sequences (100000159 bp) in 2.877 CPU sec, 2.956 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 292401, 18, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 341, 965)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2449)
[M::mem_pestat] mean and std.dev: (595.16, 585.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3191)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 200, 288)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 588)
[M::mem_pestat] mean and std.dev: (222.21, 109.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 738)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (285, 585, 1516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3978)
[M::mem_pestat] mean and std.dev: (889.67, 816.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5209)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 346, 797)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2063)
[M::mem_pestat] mean and std.dev: (491.51, 456.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2696)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 133, #reads = 1077817 mem = 536880956 peak = 1151565824
[M::process] read 713390 sequences (100000105 bp) in 3.952 CPU sec, 4.213 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 291363, 21, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (253, 495, 1708)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4618)
[M::mem_pestat] mean and std.dev: (1130.13, 1223.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6073)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (141, 205, 298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 612)
[M::mem_pestat] mean and std.dev: (229.05, 114.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 769)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (287, 350, 1621)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4289)
[M::mem_pestat] mean and std.dev: (753.40, 782.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5623)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 472, 1013)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2595)
[M::mem_pestat] mean and std.dev: (630.91, 538.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3386)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 717548 reads in 214.337 CPU sec, 6.848 real sec
[M::mem_process_seqs] Processed 714434 reads in 145.223 CPU sec, 4.591 real sec
[M::process] read 712884 sequences (100000079 bp) in 2.956 CPU sec, 3.053 real sec...
sorting block 134, #reads = 1086331 mem = 536881131 peak = 1151565824
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 291067, 20, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 245, 543)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1323)
[M::mem_pestat] mean and std.dev: (312.04, 280.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1713)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 207, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 616)
[M::mem_pestat] mean and std.dev: (230.65, 114.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 774)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 525, 832)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2052)
[M::mem_pestat] mean and std.dev: (502.39, 348.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2662)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 401, 1532)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4094)
[M::mem_pestat] mean and std.dev: (660.44, 658.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5375)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 712374 sequences (100000057 bp) in 3.367 CPU sec, 3.507 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 291122, 37, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 277, 1044)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2816)
[M::mem_pestat] mean and std.dev: (597.01, 670.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3702)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 208, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 623)
[M::mem_pestat] mean and std.dev: (232.53, 115.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 783)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (260, 1209, 3564)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10172)
[M::mem_pestat] mean and std.dev: (2087.89, 2285.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13476)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 309, 623)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1543)
[M::mem_pestat] mean and std.dev: (360.39, 287.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2003)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 713390 reads in 198.098 CPU sec, 6.302 real sec
[M::mem_process_seqs] Processed 712884 reads in 136.245 CPU sec, 4.308 real sec
[M::process] read 710936 sequences (100000038 bp) in 2.782 CPU sec, 2.845 real sec...
sorting block 135, #reads = 1091466 mem = 536879293 peak = 1151565824
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 290601, 30, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 300, 732)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1868)
[M::mem_pestat] mean and std.dev: (386.75, 301.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2436)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 210, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 632)
[M::mem_pestat] mean and std.dev: (234.23, 117.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 795)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (733, 1847, 3346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8572)
[M::mem_pestat] mean and std.dev: (1976.45, 1617.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11185)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 375, 1280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3400)
[M::mem_pestat] mean and std.dev: (683.19, 661.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4460)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 710142 sequences (100000099 bp) in 3.367 CPU sec, 3.485 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 290623, 44, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 379, 740)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1864)
[M::mem_pestat] mean and std.dev: (441.60, 360.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2426)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 212, 310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 640)
[M::mem_pestat] mean and std.dev: (236.88, 117.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 805)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 437, 736)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1730)
[M::mem_pestat] mean and std.dev: (432.84, 302.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2227)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 435, 1020)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2664)
[M::mem_pestat] mean and std.dev: (619.40, 560.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3486)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 712374 reads in 191.077 CPU sec, 6.071 real sec
[M::mem_process_seqs] Processed 710936 reads in 131.748 CPU sec, 4.158 real sec
sorting block 136, #reads = 1091424 mem = 536876793 peak = 1151565824
[M::process] read 710092 sequences (100000181 bp) in 2.857 CPU sec, 2.908 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 290106, 24, 81)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 301, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 898)
[M::mem_pestat] mean and std.dev: (284.74, 128.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1127)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 214, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 644)
[M::mem_pestat] mean and std.dev: (238.26, 118.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 810)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 578, 1373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3737)
[M::mem_pestat] mean and std.dev: (716.30, 611.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4919)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (266, 321, 912)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2204)
[M::mem_pestat] mean and std.dev: (440.61, 393.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2850)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 137, #reads = 1090884 mem = 536880204 peak = 1151565824
[M::process] read 709202 sequences (100000183 bp) in 3.307 CPU sec, 3.405 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (97, 289385, 28, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 298, 642)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1478)
[M::mem_pestat] mean and std.dev: (358.15, 276.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1896)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 215, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 644)
[M::mem_pestat] mean and std.dev: (238.98, 119.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 810)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (296, 574, 1502)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3914)
[M::mem_pestat] mean and std.dev: (798.56, 648.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5120)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 552, 1498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4012)
[M::mem_pestat] mean and std.dev: (790.47, 674.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5269)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 710142 reads in 190.610 CPU sec, 6.079 real sec
[M::mem_process_seqs] Processed 710092 reads in 131.822 CPU sec, 4.166 real sec
[M::process] read 708550 sequences (100000217 bp) in 2.915 CPU sec, 2.987 real sec...
sorting block 138, #reads = 1089310 mem = 536882627 peak = 1151565824
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 289668, 33, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 320, 859)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2139)
[M::mem_pestat] mean and std.dev: (492.74, 504.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2779)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 216, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 654)
[M::mem_pestat] mean and std.dev: (240.79, 120.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 823)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (292, 1160, 3295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9301)
[M::mem_pestat] mean and std.dev: (2349.24, 2656.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12974)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 390, 1519)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4137)
[M::mem_pestat] mean and std.dev: (926.04, 1075.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5446)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708332 sequences (100000164 bp) in 3.112 CPU sec, 3.222 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 289485, 34, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 447, 862)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2198)
[M::mem_pestat] mean and std.dev: (484.67, 436.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2866)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 218, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 658)
[M::mem_pestat] mean and std.dev: (242.56, 120.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 828)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 609, 1141)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2881)
[M::mem_pestat] mean and std.dev: (871.06, 867.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4341)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 285, 840)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2160)
[M::mem_pestat] mean and std.dev: (527.97, 455.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2820)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 709202 reads in 184.157 CPU sec, 5.847 real sec
[M::mem_process_seqs] Processed 708550 reads in 127.347 CPU sec, 4.008 real sec
[M::process] read 707822 sequences (100000236 bp) in 2.642 CPU sec, 2.662 real sec...
sorting block 139, #reads = 1089969 mem = 536880009 peak = 1151565824
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 289395, 24, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 306, 808)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2042)
[M::mem_pestat] mean and std.dev: (417.52, 401.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2659)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 219, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (243.26, 121.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 832)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (416, 873, 1900)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4868)
[M::mem_pestat] mean and std.dev: (1334.26, 1349.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6733)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 300, 751)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1863)
[M::mem_pestat] mean and std.dev: (499.27, 455.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2419)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708528 sequences (100000011 bp) in 2.985 CPU sec, 3.068 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (86, 289477, 22, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 431, 1206)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3224)
[M::mem_pestat] mean and std.dev: (596.77, 564.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4233)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 219, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 662)
[M::mem_pestat] mean and std.dev: (244.10, 121.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 833)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (451, 820, 2209)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5725)
[M::mem_pestat] mean and std.dev: (830.50, 645.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7483)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 284, 515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1191)
[M::mem_pestat] mean and std.dev: (298.39, 202.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1529)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708354 sequences (100000115 bp) in 2.272 CPU sec, 2.279 real sec...
[M::mem_process_seqs] Processed 708332 reads in 201.936 CPU sec, 6.393 real sec
sorting block 140, #reads = 1088695 mem = 536882982 peak = 1151565824
[M::mem_process_seqs] Processed 707822 reads in 139.757 CPU sec, 4.421 real sec
sorting block 141, #reads = 1086135 mem = 536878913 peak = 1151565824
[M::process] read 707788 sequences (100000296 bp) in 3.602 CPU sec, 3.739 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 288691, 24, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 413, 1476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4064)
[M::mem_pestat] mean and std.dev: (935.43, 1012.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5358)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 218, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (243.30, 121.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 832)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (419, 1161, 1613)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4001)
[M::mem_pestat] mean and std.dev: (1175.21, 866.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5195)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 408, 869)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2165)
[M::mem_pestat] mean and std.dev: (525.36, 477.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2813)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 708354 reads in 111.168 CPU sec, 3.513 real sec
[M::process] read 707002 sequences (100000097 bp) in 2.794 CPU sec, 2.850 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 289544, 34, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 610, 1053)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2719)
[M::mem_pestat] mean and std.dev: (688.59, 598.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3552)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 218, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (243.16, 121.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 832)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 615, 1694)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4582)
[M::mem_pestat] mean and std.dev: (850.88, 787.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6026)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 285, 676)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1632)
[M::mem_pestat] mean and std.dev: (418.94, 351.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2110)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 289178, 33, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 320, 813)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2147)
[M::mem_pestat] mean and std.dev: (460.00, 438.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2814)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 220, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (244.50, 122.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 836)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (561, 2236, 2410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6108)
[M::mem_pestat] mean and std.dev: (1809.45, 1168.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7957)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 352, 744)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1796)
[M::mem_pestat] mean and std.dev: (464.24, 325.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2322)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 708528 reads in 302.526 CPU sec, 9.617 real sec
[M::mem_process_seqs] Processed 707788 reads in 158.992 CPU sec, 5.027 real sec
sorting block 142, #reads = 1088044 mem = 536882288 peak = 1151565824
[M::process] read 707024 sequences (100000007 bp) in 2.975 CPU sec, 3.023 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 288684, 37, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 376, 1119)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3027)
[M::mem_pestat] mean and std.dev: (572.70, 571.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3981)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 221, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (245.93, 122.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 845)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 746, 2904)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8378)
[M::mem_pestat] mean and std.dev: (1324.50, 1472.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11115)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 546, 1044)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2732)
[M::mem_pestat] mean and std.dev: (662.09, 589.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3576)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707618 sequences (100000132 bp) in 3.097 CPU sec, 3.205 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 288632, 41, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 337, 1337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3629)
[M::mem_pestat] mean and std.dev: (734.76, 859.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4775)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 221, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (245.56, 122.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 841)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (438, 1409, 2391)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6297)
[M::mem_pestat] mean and std.dev: (1618.40, 1410.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8250)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 372, 1068)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2778)
[M::mem_pestat] mean and std.dev: (680.95, 712.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3633)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707002 reads in 188.543 CPU sec, 5.984 real sec
sorting block 143, #reads = 1088332 mem = 536879427 peak = 1151565824
[M::mem_process_seqs] Processed 707024 reads in 129.138 CPU sec, 4.065 real sec
[M::process] read 707416 sequences (100000093 bp) in 2.839 CPU sec, 2.903 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 289329, 23, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 343, 509)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1183)
[M::mem_pestat] mean and std.dev: (346.06, 259.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1520)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 219, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 656)
[M::mem_pestat] mean and std.dev: (242.66, 119.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 825)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (287, 587, 3112)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8762)
[M::mem_pestat] mean and std.dev: (1688.70, 2049.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11587)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 433, 800)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1988)
[M::mem_pestat] mean and std.dev: (475.69, 340.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2582)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 144, #reads = 1086740 mem = 536876982 peak = 1151565824
[M::process] read 706564 sequences (100000174 bp) in 3.572 CPU sec, 3.720 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 288220, 44, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 435, 1600)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4344)
[M::mem_pestat] mean and std.dev: (813.95, 893.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5716)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 219, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 656)
[M::mem_pestat] mean and std.dev: (243.50, 121.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 825)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (499, 1032, 2023)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5071)
[M::mem_pestat] mean and std.dev: (1222.40, 1043.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6595)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 412, 1579)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4245)
[M::mem_pestat] mean and std.dev: (1063.30, 1283.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6198)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707618 reads in 196.238 CPU sec, 6.251 real sec
[M::mem_process_seqs] Processed 707416 reads in 137.405 CPU sec, 4.343 real sec
[M::process] read 705918 sequences (100000022 bp) in 2.915 CPU sec, 2.964 real sec...
sorting block 145, #reads = 1087092 mem = 536881175 peak = 1151565824
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (107, 288504, 25, 103)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 338, 1455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3875)
[M::mem_pestat] mean and std.dev: (732.37, 684.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5085)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 221, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (246.03, 122.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 838)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (515, 980, 3672)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9986)
[M::mem_pestat] mean and std.dev: (2233.92, 2915.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13897)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 332, 597)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1357)
[M::mem_pestat] mean and std.dev: (384.99, 267.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1737)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706048 sequences (100000219 bp) in 3.167 CPU sec, 3.277 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 287451, 46, 92)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 283, 802)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1992)
[M::mem_pestat] mean and std.dev: (448.94, 392.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2587)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 223, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 676)
[M::mem_pestat] mean and std.dev: (248.24, 124.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 851)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (478, 966, 2493)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6523)
[M::mem_pestat] mean and std.dev: (1667.20, 1539.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8538)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 352, 632)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1494)
[M::mem_pestat] mean and std.dev: (426.91, 300.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1925)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706564 reads in 203.228 CPU sec, 6.451 real sec
[M::process] read 705540 sequences (100000021 bp) in 2.646 CPU sec, 2.686 real sec...
[M::mem_process_seqs] Processed 705918 reads in 140.946 CPU sec, 4.441 real sec
sorting block 146, #reads = 1085244 mem = 536880260 peak = 1151565824
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 288217, 38, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 258, 1439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4013)
[M::mem_pestat] mean and std.dev: (640.45, 808.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5300)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 223, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 673)
[M::mem_pestat] mean and std.dev: (248.08, 124.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 847)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (324, 837, 2216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6000)
[M::mem_pestat] mean and std.dev: (1203.24, 1168.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7892)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 400, 888)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2254)
[M::mem_pestat] mean and std.dev: (571.88, 501.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2937)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705002 sequences (100000132 bp) in 3.446 CPU sec, 3.561 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 287998, 37, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 376, 1709)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4745)
[M::mem_pestat] mean and std.dev: (890.48, 1096.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6263)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 224, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (249.27, 125.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 855)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (383, 871, 1912)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4970)
[M::mem_pestat] mean and std.dev: (1112.14, 949.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6499)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 399, 1009)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2599)
[M::mem_pestat] mean and std.dev: (585.09, 537.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3394)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706048 reads in 204.366 CPU sec, 6.476 real sec
[M::process] read 705256 sequences (100000073 bp) in 2.509 CPU sec, 2.506 real sec...
sorting block 147, #reads = 1083702 mem = 536884626 peak = 1151565824
[M::mem_process_seqs] Processed 705540 reads in 142.227 CPU sec, 4.494 real sec
sorting block 148, #reads = 1082889 mem = 536879029 peak = 1167171584
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (85, 287927, 36, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 298, 1012)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2666)
[M::mem_pestat] mean and std.dev: (525.57, 513.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3493)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 225, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (249.09, 124.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 848)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (369, 977, 2773)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7581)
[M::mem_pestat] mean and std.dev: (1463.74, 1637.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9985)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 342, 859)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2177)
[M::mem_pestat] mean and std.dev: (470.05, 391.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2836)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705162 sequences (100000237 bp) in 3.067 CPU sec, 3.161 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 287993, 50, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 322, 923)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2395)
[M::mem_pestat] mean and std.dev: (515.78, 438.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3131)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 223, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 665)
[M::mem_pestat] mean and std.dev: (247.53, 123.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 836)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (272, 696, 1659)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4433)
[M::mem_pestat] mean and std.dev: (994.02, 980.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5820)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 320, 793)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2013)
[M::mem_pestat] mean and std.dev: (456.77, 446.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2623)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704268 sequences (100000178 bp) in 2.429 CPU sec, 2.435 real sec...
[M::mem_process_seqs] Processed 705002 reads in 204.028 CPU sec, 6.457 real sec
[M::mem_process_seqs] Processed 705256 reads in 141.337 CPU sec, 4.464 real sec
sorting block 149, #reads = 1082889 mem = 536879051 peak = 1167171584
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 287475, 49, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 368, 1014)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2632)
[M::mem_pestat] mean and std.dev: (607.26, 577.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3441)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 222, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (246.53, 122.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 835)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (472, 922, 2391)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6229)
[M::mem_pestat] mean and std.dev: (1249.30, 1113.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8148)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 349, 976)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2504)
[M::mem_pestat] mean and std.dev: (537.69, 502.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3268)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704398 sequences (100000079 bp) in 3.142 CPU sec, 3.211 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 287773, 40, 87)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 414, 1614)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4434)
[M::mem_pestat] mean and std.dev: (777.12, 852.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5844)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 225, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 669)
[M::mem_pestat] mean and std.dev: (248.71, 122.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 841)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 475, 1037)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2747)
[M::mem_pestat] mean and std.dev: (579.14, 559.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3602)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 396, 1641)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4425)
[M::mem_pestat] mean and std.dev: (820.90, 843.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5817)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704662 sequences (100000114 bp) in 2.420 CPU sec, 2.416 real sec...
[M::mem_process_seqs] Processed 705162 reads in 198.230 CPU sec, 6.254 real sec
sorting block 150, #reads = 1081937 mem = 536880110 peak = 1167171584
[M::mem_process_seqs] Processed 704268 reads in 136.313 CPU sec, 4.311 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 287437, 36, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 336, 896)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2328)
[M::mem_pestat] mean and std.dev: (610.46, 636.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3158)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (249.06, 123.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 848)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 264, 923)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2337)
[M::mem_pestat] mean and std.dev: (470.74, 572.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3044)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 412, 877)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2123)
[M::mem_pestat] mean and std.dev: (553.90, 432.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2746)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704224 sequences (100000188 bp) in 2.970 CPU sec, 3.065 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 287216, 39, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 366, 1205)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3249)
[M::mem_pestat] mean and std.dev: (678.81, 674.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4271)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 225, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (249.03, 123.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 844)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (454, 1065, 2033)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5191)
[M::mem_pestat] mean and std.dev: (1113.19, 957.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6770)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 234, 991)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2579)
[M::mem_pestat] mean and std.dev: (475.78, 553.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3373)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703920 sequences (100000254 bp) in 2.410 CPU sec, 2.410 real sec...
[M::mem_process_seqs] Processed 704398 reads in 188.455 CPU sec, 5.945 real sec
sorting block 151, #reads = 1081864 mem = 536877480 peak = 1167171584
[M::mem_process_seqs] Processed 704662 reads in 129.521 CPU sec, 4.091 real sec
sorting block 152, #reads = 1082444 mem = 536878461 peak = 1167171584
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 287625, 34, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 320, 1099)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2849)
[M::mem_pestat] mean and std.dev: (546.35, 568.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3724)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 225, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 675)
[M::mem_pestat] mean and std.dev: (249.96, 124.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 849)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (447, 1285, 1835)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4611)
[M::mem_pestat] mean and std.dev: (1105.33, 985.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5999)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 356, 1024)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2736)
[M::mem_pestat] mean and std.dev: (597.92, 579.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3592)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704178 sequences (100000241 bp) in 3.192 CPU sec, 3.241 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 286650, 42, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 246, 697)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1787)
[M::mem_pestat] mean and std.dev: (415.52, 401.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2332)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 226, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 678)
[M::mem_pestat] mean and std.dev: (250.30, 124.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 853)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 803, 1531)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4143)
[M::mem_pestat] mean and std.dev: (1011.12, 984.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5449)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 335, 844)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2234)
[M::mem_pestat] mean and std.dev: (479.46, 464.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2929)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705222 sequences (100000050 bp) in 2.460 CPU sec, 2.462 real sec...
[M::mem_process_seqs] Processed 704224 reads in 196.815 CPU sec, 6.207 real sec
[M::mem_process_seqs] Processed 703920 reads in 136.025 CPU sec, 4.300 real sec
sorting block 153, #reads = 1080874 mem = 536879480 peak = 1167171584
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 286945, 38, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 268, 765)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2007)
[M::mem_pestat] mean and std.dev: (398.72, 394.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2628)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 226, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 678)
[M::mem_pestat] mean and std.dev: (250.61, 124.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 853)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 477, 877)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2243)
[M::mem_pestat] mean and std.dev: (451.61, 400.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2926)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 419, 1002)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2566)
[M::mem_pestat] mean and std.dev: (608.73, 556.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3348)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 716520 sequences (100000152 bp) in 2.962 CPU sec, 3.019 real sec...
[M::process] read 719838 sequences (100000111 bp) in 2.460 CPU sec, 2.457 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 287227, 35, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 343, 597)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1467)
[M::mem_pestat] mean and std.dev: (366.51, 273.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1902)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 223, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (247.47, 123.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 840)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (289, 643, 1654)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4384)
[M::mem_pestat] mean and std.dev: (944.66, 830.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5749)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 226, 480)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1136)
[M::mem_pestat] mean and std.dev: (277.91, 232.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1464)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704178 reads in 209.563 CPU sec, 6.626 real sec
sorting block 154, #reads = 1079393 mem = 536878096 peak = 1167171584
[M::process] read 718088 sequences (100000067 bp) in 2.943 CPU sec, 2.952 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 293037, 24, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (252, 489, 1356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3564)
[M::mem_pestat] mean and std.dev: (882.74, 890.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4668)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 195, 280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 568)
[M::mem_pestat] mean and std.dev: (217.09, 105.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 712)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (427, 1153, 1979)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5083)
[M::mem_pestat] mean and std.dev: (1206.33, 1001.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6635)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 323, 976)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2562)
[M::mem_pestat] mean and std.dev: (468.45, 454.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3355)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 719838 reads in 116.044 CPU sec, 3.662 real sec
[M::mem_process_seqs] Processed 705222 reads in 292.635 CPU sec, 9.275 real sec
sorting block 155, #reads = 1084472 mem = 536877860 peak = 1167171584
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 291342, 25, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 246, 678)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1682)
[M::mem_pestat] mean and std.dev: (397.55, 339.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2184)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 200, 289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 589)
[M::mem_pestat] mean and std.dev: (223.19, 110.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 739)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 683, 1612)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4392)
[M::mem_pestat] mean and std.dev: (1019.44, 963.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5782)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 363, 928)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2374)
[M::mem_pestat] mean and std.dev: (525.88, 500.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3097)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 716328 sequences (100000221 bp) in 3.316 CPU sec, 3.391 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 292322, 31, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 293, 883)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2263)
[M::mem_pestat] mean and std.dev: (515.85, 503.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2953)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 199, 287)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 587)
[M::mem_pestat] mean and std.dev: (221.34, 108.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 737)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (392, 566, 1651)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4169)
[M::mem_pestat] mean and std.dev: (784.22, 840.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5428)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 434, 814)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2072)
[M::mem_pestat] mean and std.dev: (495.62, 429.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2701)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 715530 sequences (100000246 bp) in 2.510 CPU sec, 2.506 real sec...
[M::mem_process_seqs] Processed 716520 reads in 328.498 CPU sec, 10.373 real sec
[M::mem_process_seqs] Processed 718088 reads in 143.661 CPU sec, 4.545 real sec
sorting block 156, #reads = 1073889 mem = 536878144 peak = 1167171584
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 292091, 26, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 443, 942)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2460)
[M::mem_pestat] mean and std.dev: (578.17, 482.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3219)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 202, 292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 598)
[M::mem_pestat] mean and std.dev: (225.18, 111.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 751)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (439, 841, 2941)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7945)
[M::mem_pestat] mean and std.dev: (1795.62, 1843.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10447)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 322, 864)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2192)
[M::mem_pestat] mean and std.dev: (462.65, 440.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2856)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 713978 sequences (100000011 bp) in 3.084 CPU sec, 3.160 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 291944, 30, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 312, 731)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1867)
[M::mem_pestat] mean and std.dev: (426.60, 373.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2435)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (140, 203, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 605)
[M::mem_pestat] mean and std.dev: (227.09, 112.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 760)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 906, 1930)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5384)
[M::mem_pestat] mean and std.dev: (1156.93, 1054.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7111)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 290, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 959)
[M::mem_pestat] mean and std.dev: (255.70, 120.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1220)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 713472 sequences (100000222 bp) in 2.440 CPU sec, 2.443 real sec...
[M::mem_process_seqs] Processed 716328 reads in 197.043 CPU sec, 6.224 real sec
sorting block 157, #reads = 1087915 mem = 536878512 peak = 1167171584
[M::mem_process_seqs] Processed 715530 reads in 134.260 CPU sec, 4.243 real sec
sorting block 158, #reads = 1086410 mem = 536879189 peak = 1167171584
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 291212, 36, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 794, 1344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3682)
[M::mem_pestat] mean and std.dev: (727.63, 631.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4851)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (141, 206, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 618)
[M::mem_pestat] mean and std.dev: (230.28, 114.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 777)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (107, 575, 1470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4196)
[M::mem_pestat] mean and std.dev: (906.42, 932.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5559)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 379, 1121)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2949)
[M::mem_pestat] mean and std.dev: (606.85, 620.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3863)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 712362 sequences (100000164 bp) in 3.412 CPU sec, 3.549 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 291355, 37, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 248, 1206)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3270)
[M::mem_pestat] mean and std.dev: (530.10, 626.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4302)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 208, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 622)
[M::mem_pestat] mean and std.dev: (231.91, 115.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 782)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (464, 1086, 1989)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5039)
[M::mem_pestat] mean and std.dev: (1224.33, 990.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6564)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 395, 885)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2217)
[M::mem_pestat] mean and std.dev: (551.77, 458.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2883)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 711586 sequences (100000201 bp) in 2.424 CPU sec, 2.436 real sec...
[M::mem_process_seqs] Processed 713978 reads in 195.021 CPU sec, 6.150 real sec
[M::mem_process_seqs] Processed 713472 reads in 134.052 CPU sec, 4.233 real sec
sorting block 159, #reads = 1085509 mem = 536878934 peak = 1167171584
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 290206, 24, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 328, 692)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1676)
[M::mem_pestat] mean and std.dev: (393.53, 329.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2168)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 209, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 629)
[M::mem_pestat] mean and std.dev: (233.68, 116.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 791)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (716, 2603, 4076)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10796)
[M::mem_pestat] mean and std.dev: (2793.25, 2513.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14156)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 341, 764)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1870)
[M::mem_pestat] mean and std.dev: (413.67, 319.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2423)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 710994 sequences (100000288 bp) in 2.742 CPU sec, 2.791 real sec...
[M::process] read 710196 sequences (100000092 bp) in 2.340 CPU sec, 2.345 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 289869, 29, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 500, 1290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3478)
[M::mem_pestat] mean and std.dev: (745.79, 658.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4572)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 211, 309)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 639)
[M::mem_pestat] mean and std.dev: (236.23, 118.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 804)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (397, 511, 1271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3019)
[M::mem_pestat] mean and std.dev: (710.84, 495.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3893)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 350, 1142)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3014)
[M::mem_pestat] mean and std.dev: (639.28, 635.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3950)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 712362 reads in 191.656 CPU sec, 6.053 real sec
sorting block 160, #reads = 1085695 mem = 536877979 peak = 1167171584
[M::mem_process_seqs] Processed 711586 reads in 131.946 CPU sec, 4.183 real sec
[M::process] read 710110 sequences (100000283 bp) in 2.511 CPU sec, 2.587 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 289943, 23, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 376, 1649)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4473)
[M::mem_pestat] mean and std.dev: (787.43, 890.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5885)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 212, 310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 640)
[M::mem_pestat] mean and std.dev: (236.91, 118.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 805)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (330, 641, 901)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2043)
[M::mem_pestat] mean and std.dev: (682.48, 523.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2778)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 365, 934)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2418)
[M::mem_pestat] mean and std.dev: (565.74, 475.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3160)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 710916 sequences (100000209 bp) in 1.870 CPU sec, 1.864 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 289747, 33, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 429, 825)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2027)
[M::mem_pestat] mean and std.dev: (543.75, 484.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2628)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 215, 314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 650)
[M::mem_pestat] mean and std.dev: (239.46, 119.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 818)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (618, 1348, 3249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8511)
[M::mem_pestat] mean and std.dev: (2127.39, 1871.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11142)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 647, 1913)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5293)
[M::mem_pestat] mean and std.dev: (1119.44, 1241.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6983)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 710994 reads in 186.961 CPU sec, 5.921 real sec
sorting block 161, #reads = 1083825 mem = 536878956 peak = 1167171584
[M::mem_process_seqs] Processed 710196 reads in 210.074 CPU sec, 6.674 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 290157, 36, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 407, 940)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2476)
[M::mem_pestat] mean and std.dev: (560.31, 547.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3244)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 215, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653)
[M::mem_pestat] mean and std.dev: (240.04, 120.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 822)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (347, 712, 1587)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4067)
[M::mem_pestat] mean and std.dev: (814.21, 689.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5307)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 280, 1283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3581)
[M::mem_pestat] mean and std.dev: (755.50, 846.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4730)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 162, #reads = 1084646 mem = 536881283 peak = 1167171584
[M::process] read 709898 sequences (100000270 bp) in 3.357 CPU sec, 3.492 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 290209, 28, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (293, 700, 2136)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5822)
[M::mem_pestat] mean and std.dev: (1123.64, 1144.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7665)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 213, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 646)
[M::mem_pestat] mean and std.dev: (238.51, 119.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 813)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (318, 495, 1215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3009)
[M::mem_pestat] mean and std.dev: (655.08, 525.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3906)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 378, 972)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2576)
[M::mem_pestat] mean and std.dev: (624.30, 615.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3378)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 710110 reads in 185.959 CPU sec, 5.880 real sec
[M::mem_process_seqs] Processed 710916 reads in 132.036 CPU sec, 4.162 real sec
[M::process] read 709604 sequences (100000035 bp) in 3.166 CPU sec, 3.204 real sec...
sorting block 163, #reads = 1084204 mem = 536879367 peak = 1167171584
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 289042, 15, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 358, 757)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1909)
[M::mem_pestat] mean and std.dev: (410.36, 311.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2485)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 214, 314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 650)
[M::mem_pestat] mean and std.dev: (240.22, 120.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 818)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (291, 785, 1767)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4719)
[M::mem_pestat] mean and std.dev: (1218.40, 1195.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6195)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (272, 413, 1348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3500)
[M::mem_pestat] mean and std.dev: (844.36, 829.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4576)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 709148 sequences (100000298 bp) in 3.162 CPU sec, 3.269 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 289592, 20, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 268, 683)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1731)
[M::mem_pestat] mean and std.dev: (449.02, 444.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2255)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 216, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 656)
[M::mem_pestat] mean and std.dev: (241.11, 121.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 826)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (23, 581, 1541)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4577)
[M::mem_pestat] mean and std.dev: (618.83, 651.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6095)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 343, 919)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2335)
[M::mem_pestat] mean and std.dev: (443.75, 391.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3043)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 710850 sequences (100000158 bp) in 1.830 CPU sec, 1.829 real sec...
[M::mem_process_seqs] Processed 709898 reads in 186.698 CPU sec, 5.920 real sec
[M::mem_process_seqs] Processed 709604 reads in 126.836 CPU sec, 4.013 real sec
sorting block 164, #reads = 1083031 mem = 536883209 peak = 1167171584
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 289496, 27, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 291, 1373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3771)
[M::mem_pestat] mean and std.dev: (511.82, 548.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4970)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 216, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 656)
[M::mem_pestat] mean and std.dev: (241.54, 121.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 826)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 333, 402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 838)
[M::mem_pestat] mean and std.dev: (280.24, 197.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1070)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 357, 1373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3745)
[M::mem_pestat] mean and std.dev: (770.54, 783.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4931)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707134 sequences (100000147 bp) in 2.535 CPU sec, 2.605 real sec...
[M::process] read 706542 sequences (100000116 bp) in 1.790 CPU sec, 1.791 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 289869, 25, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 313, 976)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2654)
[M::mem_pestat] mean and std.dev: (476.93, 453.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3493)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 211, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 625)
[M::mem_pestat] mean and std.dev: (234.33, 115.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 785)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (317, 891, 1455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3731)
[M::mem_pestat] mean and std.dev: (1025.96, 914.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4869)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 331, 1338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3622)
[M::mem_pestat] mean and std.dev: (660.09, 789.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4764)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 709148 reads in 189.440 CPU sec, 6.020 real sec
sorting block 165, #reads = 1085767 mem = 536880288 peak = 1167171584
[M::mem_process_seqs] Processed 710850 reads in 130.984 CPU sec, 4.172 real sec
sorting block 166, #reads = 1084136 mem = 536879074 peak = 1167171584
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 288339, 41, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 413, 1385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3675)
[M::mem_pestat] mean and std.dev: (765.89, 786.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4820)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 220, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 654)
[M::mem_pestat] mean and std.dev: (243.55, 120.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 822)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 678, 2364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6616)
[M::mem_pestat] mean and std.dev: (1247.80, 1237.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8742)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 404, 709)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1787)
[M::mem_pestat] mean and std.dev: (435.85, 340.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2326)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705670 sequences (100000106 bp) in 3.163 CPU sec, 3.235 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 288220, 30, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 287, 977)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2577)
[M::mem_pestat] mean and std.dev: (474.48, 514.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3377)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 221, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 660)
[M::mem_pestat] mean and std.dev: (244.58, 120.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 830)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 1135, 1882)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5288)
[M::mem_pestat] mean and std.dev: (1243.13, 1332.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6991)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 334, 640)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1504)
[M::mem_pestat] mean and std.dev: (374.98, 259.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1936)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705286 sequences (100000028 bp) in 2.370 CPU sec, 2.378 real sec...
[M::mem_process_seqs] Processed 707134 reads in 187.712 CPU sec, 5.922 real sec
[M::mem_process_seqs] Processed 706542 reads in 129.155 CPU sec, 4.079 real sec
sorting block 167, #reads = 1081026 mem = 536878792 peak = 1167171584
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 287789, 37, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 403, 1047)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2683)
[M::mem_pestat] mean and std.dev: (581.06, 602.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3501)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 223, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 670)
[M::mem_pestat] mean and std.dev: (247.43, 122.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 843)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (504, 985, 1930)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4782)
[M::mem_pestat] mean and std.dev: (1106.26, 865.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6208)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (282, 483, 1115)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2781)
[M::mem_pestat] mean and std.dev: (749.82, 583.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3614)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704362 sequences (100000203 bp) in 2.818 CPU sec, 2.872 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 287646, 39, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 357, 758)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1918)
[M::mem_pestat] mean and std.dev: (397.38, 258.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2498)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (247.86, 122.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 840)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (452, 694, 1321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3059)
[M::mem_pestat] mean and std.dev: (787.44, 554.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3928)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 405, 1628)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4466)
[M::mem_pestat] mean and std.dev: (752.12, 864.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5885)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704658 sequences (100000254 bp) in 2.240 CPU sec, 2.239 real sec...
[M::mem_process_seqs] Processed 705670 reads in 184.151 CPU sec, 5.828 real sec
[M::mem_process_seqs] Processed 705286 reads in 127.326 CPU sec, 4.017 real sec
sorting block 168, #reads = 1082080 mem = 536882174 peak = 1167171584
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (81, 286768, 44, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 289, 553)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1281)
[M::mem_pestat] mean and std.dev: (359.26, 250.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1645)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 225, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (248.64, 122.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 844)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 786, 2033)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5629)
[M::mem_pestat] mean and std.dev: (1125.56, 1168.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7427)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 280, 705)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1711)
[M::mem_pestat] mean and std.dev: (408.09, 330.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2214)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704346 sequences (100000104 bp) in 3.067 CPU sec, 3.131 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 287755, 37, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 291, 593)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1487)
[M::mem_pestat] mean and std.dev: (338.30, 269.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1934)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 665)
[M::mem_pestat] mean and std.dev: (247.26, 121.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 836)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (464, 1062, 2759)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7349)
[M::mem_pestat] mean and std.dev: (1375.65, 1208.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9644)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 523, 1308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3436)
[M::mem_pestat] mean and std.dev: (769.62, 716.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4500)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704362 reads in 181.679 CPU sec, 5.735 real sec
[M::process] read 703804 sequences (100000178 bp) in 2.340 CPU sec, 2.336 real sec...
[M::mem_process_seqs] Processed 704658 reads in 124.540 CPU sec, 3.924 real sec
sorting block 169, #reads = 1082965 mem = 536883281 peak = 1167171584
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 287021, 27, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 257, 552)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1326)
[M::mem_pestat] mean and std.dev: (415.26, 362.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1866)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 659)
[M::mem_pestat] mean and std.dev: (246.26, 119.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 828)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (629, 1611, 3053)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7901)
[M::mem_pestat] mean and std.dev: (1920.52, 1714.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10325)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 370, 1144)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2946)
[M::mem_pestat] mean and std.dev: (741.20, 698.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3847)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703418 sequences (100000147 bp) in 2.086 CPU sec, 2.132 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 287457, 23, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 403, 1059)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2815)
[M::mem_pestat] mean and std.dev: (623.27, 546.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3693)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 226, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (247.90, 120.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 830)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (310, 755, 1640)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4300)
[M::mem_pestat] mean and std.dev: (601.06, 508.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5630)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (266, 388, 1420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3728)
[M::mem_pestat] mean and std.dev: (758.97, 731.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4882)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703084 sequences (100000095 bp) in 1.630 CPU sec, 1.636 real sec...
[M::mem_process_seqs] Processed 704346 reads in 144.287 CPU sec, 4.581 real sec
sorting block 170, #reads = 1082507 mem = 536877923 peak = 1174458368
[M::mem_process_seqs] Processed 703804 reads in 97.905 CPU sec, 3.096 real sec
sorting block 171, #reads = 1082211 mem = 536881205 peak = 1204023296
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 286963, 33, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 400, 2130)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6044)
[M::mem_pestat] mean and std.dev: (841.97, 1127.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8001)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667)
[M::mem_pestat] mean and std.dev: (249.26, 121.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 838)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (258, 486, 1448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3828)
[M::mem_pestat] mean and std.dev: (769.93, 889.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5018)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 358, 1379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3717)
[M::mem_pestat] mean and std.dev: (867.49, 977.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4886)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702944 sequences (100000088 bp) in 2.683 CPU sec, 2.732 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 287248, 31, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 270, 535)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1241)
[M::mem_pestat] mean and std.dev: (297.41, 169.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1594)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667)
[M::mem_pestat] mean and std.dev: (249.24, 121.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 838)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (411, 502, 1510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3708)
[M::mem_pestat] mean and std.dev: (828.71, 632.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4807)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 425, 1110)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2874)
[M::mem_pestat] mean and std.dev: (627.21, 666.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3756)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703418 reads in 159.163 CPU sec, 5.012 real sec
[M::process] read 703148 sequences (100000029 bp) in 2.300 CPU sec, 2.296 real sec...
[M::mem_process_seqs] Processed 703084 reads in 114.941 CPU sec, 3.614 real sec
sorting block 172, #reads = 1081723 mem = 536883514 peak = 1204023296
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 286233, 40, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 264, 612)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1502)
[M::mem_pestat] mean and std.dev: (376.96, 307.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1947)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 228, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (251.01, 122.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 847)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (309, 752, 1180)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2922)
[M::mem_pestat] mean and std.dev: (714.63, 615.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3793)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 323, 753)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1807)
[M::mem_pestat] mean and std.dev: (391.29, 311.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2334)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702016 sequences (100000176 bp) in 2.781 CPU sec, 2.830 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 287322, 42, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 367, 494)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1190)
[M::mem_pestat] mean and std.dev: (297.90, 216.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1538)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (251.93, 124.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 1252, 2595)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7285)
[M::mem_pestat] mean and std.dev: (1361.55, 1355.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9630)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 285, 573)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1353)
[M::mem_pestat] mean and std.dev: (358.26, 258.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1743)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702944 reads in 165.499 CPU sec, 5.234 real sec
[M::process] read 702560 sequences (100000293 bp) in 2.431 CPU sec, 2.435 real sec...
[M::mem_process_seqs] Processed 703148 reads in 113.537 CPU sec, 3.567 real sec
sorting block 173, #reads = 1082718 mem = 536878429 peak = 1204023296
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 286547, 32, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 413, 1075)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2791)
[M::mem_pestat] mean and std.dev: (640.78, 629.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3649)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 231, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (254.21, 124.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (343, 1070, 2637)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7225)
[M::mem_pestat] mean and std.dev: (1617.41, 1765.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9519)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 322, 1213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3241)
[M::mem_pestat] mean and std.dev: (589.95, 553.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4255)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702202 sequences (100000147 bp) in 2.625 CPU sec, 2.707 real sec...
[M::process] read 268314 sequences (38026933 bp) in 1.060 CPU sec, 1.061 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 287311, 43, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 464, 1389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3679)
[M::mem_pestat] mean and std.dev: (795.16, 833.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4824)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 229, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 686)
[M::mem_pestat] mean and std.dev: (253.87, 126.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 863)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (494, 834, 2168)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5516)
[M::mem_pestat] mean and std.dev: (1395.49, 1351.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7190)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 280, 1763)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4975)
[M::mem_pestat] mean and std.dev: (851.03, 1025.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6581)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702016 reads in 161.139 CPU sec, 5.124 real sec
sorting block 174, #reads = 1083022 mem = 536879325 peak = 1204023296
[M::mem_process_seqs] Processed 702560 reads in 111.458 CPU sec, 3.542 real sec
sorting block 175, #reads = 1082091 mem = 536877905 peak = 1204023296
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 286626, 31, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 362, 791)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2005)
[M::mem_pestat] mean and std.dev: (476.30, 370.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2612)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 231, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (255.17, 126.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 872)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (432, 1165, 2484)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6588)
[M::mem_pestat] mean and std.dev: (1375.72, 1281.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8640)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 299, 1253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3345)
[M::mem_pestat] mean and std.dev: (500.06, 542.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4391)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 109340, 7, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 347, 881)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2251)
[M::mem_pestat] mean and std.dev: (505.88, 407.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2936)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (248.68, 123.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 848)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 331, 715)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1665)
[M::mem_pestat] mean and std.dev: (458.71, 359.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2140)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702202 reads in 118.987 CPU sec, 3.853 real sec
[M::mem_process_seqs] Processed 268314 reads in 58.464 CPU sec, 1.897 real sec
sorting block 176, #reads = 1082287 mem = 536883476 peak = 1204023296
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000c06f2
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: INTEL(R) XEON(R) PLATINUM 8559C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 190976980
overall: 70095708160 mem 30763.049 user 576.382 sys 1014.316 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1136_7GC-T1-TDNA-1_A23MHWWLT4_1.L004\tPU:L004\tSM:1136_7GC-T1-TDNA-1_A23MHWWLT4_1\tLB:1136_7GC-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1136_7GC-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1136_7GC-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 1014.359 sec; CPU: 31339.435 sec
sorting block 177, #reads = 127689 mem = 63726091 peak = 1204023296
uniq header count 1
merging 178 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000c06f2
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: INTEL(R) XEON(R) PLATINUM 8559C
threads: 31 max 192
algo: util-sort
license: sentieon:util=1
output file size: 10281048715
output reads: 192242668
bam_mem_sort: 178 calls 116.505 user 2.231 sys 119.015 real
bam_write: 178 calls 79.197 user 5.074 sys 94.058 real
execute: 1 calls 59.746 user 2.063 sys 1088.407 real
merge_files: 1 calls 59.706 user 2.032 sys 73.942 real
parse_chunk: 2834 calls 167.329 user 41.678 sys 214.161 real
read_chunk: 7667 calls 90.588 user 57.334 sys 982.257 real
sort_block: 1 calls 65.898 user 56.741 sys 947.823 real
write_chunk: 4831 calls 59.323 user 1.649 sys 72.792 real
overall: 3738730496 mem 3001.590 user 140.062 sys 1088.432 real
ls: cannot access '*.cram': No such file or directory