cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 659_dm4-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 1894.554 CPU sec, 69.403 real sec
[M::process] read 757318 sequences (100000034 bp) in 1.635 CPU sec, 1.646 real sec...
[M::process] read 755850 sequences (100000196 bp) in 1.970 CPU sec, 1.971 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 304368, 25, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 241, 714)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1876)
[M::mem_pestat] mean and std.dev: (370.35, 396.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2457)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 154, 209)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 397)
[M::mem_pestat] mean and std.dev: (166.53, 68.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 491)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (125, 298, 793)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2129)
[M::mem_pestat] mean and std.dev: (479.67, 468.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2797)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 251, 833)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2187)
[M::mem_pestat] mean and std.dev: (483.49, 558.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2864)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 755372 sequences (100000174 bp) in 2.042 CPU sec, 2.047 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 303912, 12, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 265, 1394)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3826)
[M::mem_pestat] mean and std.dev: (648.70, 731.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5042)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 156, 211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 403)
[M::mem_pestat] mean and std.dev: (167.83, 69.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 499)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (83, 863, 1233)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3533)
[M::mem_pestat] mean and std.dev: (877.67, 837.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4683)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 273, 486)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1144)
[M::mem_pestat] mean and std.dev: (303.51, 199.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1473)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 756182 sequences (100000041 bp) in 1.996 CPU sec, 2.000 real sec...
[M::mem_process_seqs] Processed 757318 reads in 205.176 CPU sec, 6.441 real sec
[M::mem_process_seqs] Processed 755850 reads in 144.557 CPU sec, 4.596 real sec
sorting block 0, #reads = 1118478 mem = 536880213 peak = 567701504
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 303898, 20, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 521, 1587)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4411)
[M::mem_pestat] mean and std.dev: (729.76, 796.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5823)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 156, 212)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 406)
[M::mem_pestat] mean and std.dev: (168.91, 70.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 503)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 1003, 2305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6545)
[M::mem_pestat] mean and std.dev: (1239.80, 1492.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8665)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 219, 711)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1803)
[M::mem_pestat] mean and std.dev: (358.00, 308.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2349)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 754116 sequences (100000024 bp) in 3.098 CPU sec, 3.214 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 304423, 24, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 280, 813)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2143)
[M::mem_pestat] mean and std.dev: (446.75, 457.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2808)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 755364 sequences (100000086 bp) in 2.360 CPU sec, 2.359 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (115, 156, 212)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 406)
[M::mem_pestat] mean and std.dev: (168.58, 70.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 503)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (272, 935, 1308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3380)
[M::mem_pestat] mean and std.dev: (830.78, 697.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4416)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 201, 309)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 601)
[M::mem_pestat] mean and std.dev: (226.46, 103.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 747)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 755372 reads in 220.176 CPU sec, 7.196 real sec
[M::mem_process_seqs] Processed 756182 reads in 148.504 CPU sec, 4.736 real sec
sorting block 1, #reads = 1118310 mem = 536878487 peak = 723140608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 303953, 39, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 320, 731)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1903)
[M::mem_pestat] mean and std.dev: (443.41, 419.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2489)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 157, 214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 410)
[M::mem_pestat] mean and std.dev: (170.06, 71.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 508)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 360, 1127)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3099)
[M::mem_pestat] mean and std.dev: (578.03, 630.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4085)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 306, 722)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1844)
[M::mem_pestat] mean and std.dev: (422.60, 433.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2405)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 754104 sequences (100000166 bp) in 2.980 CPU sec, 3.058 real sec...
[M::process] read 753032 sequences (100000276 bp) in 2.265 CPU sec, 2.291 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 304226, 12, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 568, 1494)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4072)
[M::mem_pestat] mean and std.dev: (752.95, 806.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5361)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 156, 212)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 406)
[M::mem_pestat] mean and std.dev: (169.04, 70.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 503)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 475, 688)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1638)
[M::mem_pestat] mean and std.dev: (426.42, 313.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2113)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 301, 1206)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3262)
[M::mem_pestat] mean and std.dev: (590.58, 694.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4290)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 754116 reads in 212.993 CPU sec, 6.786 real sec
sorting block 2, #reads = 1119259 mem = 536883457 peak = 768851968
[M::process] read 752864 sequences (100000191 bp) in 2.509 CPU sec, 2.517 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 303532, 34, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 225, 519)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1235)
[M::mem_pestat] mean and std.dev: (257.68, 170.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1593)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 157, 214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 410)
[M::mem_pestat] mean and std.dev: (170.07, 71.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 508)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (360, 466, 621)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1143)
[M::mem_pestat] mean and std.dev: (441.93, 190.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1404)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 201, 697)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1789)
[M::mem_pestat] mean and std.dev: (459.93, 474.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2358)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 754104 reads in 117.920 CPU sec, 4.107 real sec
sorting block 3, #reads = 1117743 mem = 536875424 peak = 775438336
[M::mem_process_seqs] Processed 755364 reads in 310.273 CPU sec, 10.276 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 303556, 14, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1129)
[M::mem_pestat] mean and std.dev: (269.90, 242.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1461)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 158, 215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 413)
[M::mem_pestat] mean and std.dev: (171.13, 72.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 512)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 575, 810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1978)
[M::mem_pestat] mean and std.dev: (586.86, 415.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2562)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 408, 1395)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3813)
[M::mem_pestat] mean and std.dev: (690.92, 702.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5022)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 751752 sequences (100000045 bp) in 3.055 CPU sec, 3.162 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 302861, 19, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 260, 391)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 849)
[M::mem_pestat] mean and std.dev: (236.73, 107.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1078)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 158, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 416)
[M::mem_pestat] mean and std.dev: (171.44, 72.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 516)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 1129, 1324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3442)
[M::mem_pestat] mean and std.dev: (696.25, 517.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4501)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 231, 958)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2526)
[M::mem_pestat] mean and std.dev: (474.22, 488.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3310)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 753032 reads in 244.724 CPU sec, 7.859 real sec
[M::process] read 752060 sequences (100000147 bp) in 2.648 CPU sec, 2.672 real sec...
sorting block 4, #reads = 1118104 mem = 536882447 peak = 775438336
[M::mem_process_seqs] Processed 752864 reads in 152.465 CPU sec, 4.838 real sec
sorting block 5, #reads = 1117513 mem = 536879481 peak = 804958208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 302357, 28, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 227, 878)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2324)
[M::mem_pestat] mean and std.dev: (488.08, 482.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3047)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 417)
[M::mem_pestat] mean and std.dev: (172.26, 72.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 517)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (536, 897, 2557)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6599)
[M::mem_pestat] mean and std.dev: (1479.64, 1335.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8620)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 229, 630)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1474)
[M::mem_pestat] mean and std.dev: (349.20, 265.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1896)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 751482 sequences (100000059 bp) in 3.680 CPU sec, 3.860 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 302810, 15, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 291, 975)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2585)
[M::mem_pestat] mean and std.dev: (444.48, 430.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3390)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 414)
[M::mem_pestat] mean and std.dev: (171.79, 72.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 513)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 462, 1115)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2895)
[M::mem_pestat] mean and std.dev: (599.43, 532.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3785)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 404, 1310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3548)
[M::mem_pestat] mean and std.dev: (632.56, 636.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4667)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 750726 sequences (100000286 bp) in 2.400 CPU sec, 2.404 real sec...
[M::mem_process_seqs] Processed 751752 reads in 227.400 CPU sec, 7.502 real sec
[M::mem_process_seqs] Processed 752060 reads in 153.037 CPU sec, 4.998 real sec
sorting block 6, #reads = 1116646 mem = 536879952 peak = 804958208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 302722, 35, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 408, 956)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2496)
[M::mem_pestat] mean and std.dev: (484.02, 418.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3266)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 417)
[M::mem_pestat] mean and std.dev: (172.43, 73.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 517)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 1367, 3614)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10452)
[M::mem_pestat] mean and std.dev: (2635.94, 2955.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14459)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 353, 776)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1850)
[M::mem_pestat] mean and std.dev: (459.52, 371.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2387)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 749038 sequences (100000026 bp) in 3.700 CPU sec, 4.027 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 302538, 36, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (127, 239, 490)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1216)
[M::mem_pestat] mean and std.dev: (316.57, 248.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1579)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 420)
[M::mem_pestat] mean and std.dev: (173.09, 73.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 521)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 766, 1143)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3039)
[M::mem_pestat] mean and std.dev: (733.31, 491.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3987)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 319, 1125)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3033)
[M::mem_pestat] mean and std.dev: (492.03, 509.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3987)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 751482 reads in 227.830 CPU sec, 7.367 real sec
[M::process] read 748210 sequences (100000203 bp) in 2.786 CPU sec, 2.808 real sec...
[M::mem_process_seqs] Processed 750726 reads in 157.700 CPU sec, 5.250 real sec
sorting block 7, #reads = 1117318 mem = 536884523 peak = 804958208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 301491, 31, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 541, 1093)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2993)
[M::mem_pestat] mean and std.dev: (547.30, 422.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3943)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 161, 220)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 424)
[M::mem_pestat] mean and std.dev: (174.61, 74.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 526)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (660, 818, 1543)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3309)
[M::mem_pestat] mean and std.dev: (980.64, 886.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4527)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 343, 734)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1876)
[M::mem_pestat] mean and std.dev: (463.16, 448.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2447)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 747720 sequences (100000093 bp) in 3.599 CPU sec, 3.736 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 301601, 24, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 289, 551)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1259)
[M::mem_pestat] mean and std.dev: (342.97, 204.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1613)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 161, 221)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 427)
[M::mem_pestat] mean and std.dev: (175.33, 74.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 530)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (580, 679, 2441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6163)
[M::mem_pestat] mean and std.dev: (1189.57, 1163.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8024)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 297, 1382)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3742)
[M::mem_pestat] mean and std.dev: (607.31, 744.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4922)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 747580 sequences (100000163 bp) in 2.299 CPU sec, 2.305 real sec...
[M::mem_process_seqs] Processed 749038 reads in 219.803 CPU sec, 7.254 real sec
sorting block 8, #reads = 1116291 mem = 536877667 peak = 804958208
[M::mem_process_seqs] Processed 748210 reads in 150.146 CPU sec, 4.890 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 301724, 32, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 262, 1390)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3798)
[M::mem_pestat] mean and std.dev: (474.04, 577.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5002)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 162, 222)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 428)
[M::mem_pestat] mean and std.dev: (175.97, 75.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 531)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (353, 899, 2555)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6959)
[M::mem_pestat] mean and std.dev: (1579.97, 1697.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9161)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 191, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1033)
[M::mem_pestat] mean and std.dev: (209.41, 123.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1328)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 9, #reads = 1114319 mem = 536877837 peak = 815497216
[M::process] read 747220 sequences (100000171 bp) in 4.151 CPU sec, 4.340 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 301618, 29, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 280, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (231.55, 110.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 952)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 162, 221)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 425)
[M::mem_pestat] mean and std.dev: (175.28, 74.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 527)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (114, 935, 1897)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5463)
[M::mem_pestat] mean and std.dev: (1155.66, 1175.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7246)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 369, 1177)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3187)
[M::mem_pestat] mean and std.dev: (688.00, 692.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4192)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 747720 reads in 211.723 CPU sec, 6.872 real sec
[M::mem_process_seqs] Processed 747580 reads in 148.958 CPU sec, 4.717 real sec
[M::process] read 746664 sequences (100000235 bp) in 2.880 CPU sec, 2.991 real sec...
sorting block 10, #reads = 1115117 mem = 536879445 peak = 815497216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 300922, 27, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 203, 803)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2095)
[M::mem_pestat] mean and std.dev: (407.28, 390.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2741)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 162, 220)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 422)
[M::mem_pestat] mean and std.dev: (175.01, 73.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 523)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 301, 1023)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2643)
[M::mem_pestat] mean and std.dev: (584.00, 661.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3453)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 322, 903)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2345)
[M::mem_pestat] mean and std.dev: (513.64, 547.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3066)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 746590 sequences (100000278 bp) in 3.354 CPU sec, 3.499 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 300561, 32, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 424, 639)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1625)
[M::mem_pestat] mean and std.dev: (419.77, 339.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2118)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 162, 221)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 425)
[M::mem_pestat] mean and std.dev: (175.49, 74.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 527)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (126, 429, 2206)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6366)
[M::mem_pestat] mean and std.dev: (1160.78, 1492.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8446)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 209, 488)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1178)
[M::mem_pestat] mean and std.dev: (275.25, 213.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1523)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 747220 reads in 214.685 CPU sec, 6.823 real sec
[M::process] read 746800 sequences (100000122 bp) in 3.171 CPU sec, 3.225 real sec...
[M::mem_process_seqs] Processed 746664 reads in 151.228 CPU sec, 4.779 real sec
sorting block 11, #reads = 1112085 mem = 536880966 peak = 815497216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 301072, 30, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 415, 1491)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4119)
[M::mem_pestat] mean and std.dev: (793.38, 858.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5433)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 162, 221)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 425)
[M::mem_pestat] mean and std.dev: (175.43, 73.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 527)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (95, 648, 1728)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4994)
[M::mem_pestat] mean and std.dev: (994.93, 1088.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6627)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 234, 990)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2612)
[M::mem_pestat] mean and std.dev: (475.19, 465.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3423)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 747244 sequences (100000161 bp) in 3.351 CPU sec, 3.511 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 300918, 27, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 222, 696)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1800)
[M::mem_pestat] mean and std.dev: (376.37, 342.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2352)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 162, 221)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 425)
[M::mem_pestat] mean and std.dev: (175.57, 74.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 527)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 956, 1273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3367)
[M::mem_pestat] mean and std.dev: (642.04, 549.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4414)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 286, 669)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1675)
[M::mem_pestat] mean and std.dev: (366.82, 339.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2178)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 746590 reads in 219.430 CPU sec, 7.146 real sec
[M::process] read 747640 sequences (100000265 bp) in 2.696 CPU sec, 2.710 real sec...
sorting block 12, #reads = 1111417 mem = 536880027 peak = 815497216
[M::mem_process_seqs] Processed 746800 reads in 154.631 CPU sec, 5.181 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 300880, 30, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 266, 1632)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4568)
[M::mem_pestat] mean and std.dev: (757.65, 1096.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6036)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 162, 220)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 422)
[M::mem_pestat] mean and std.dev: (174.69, 73.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 523)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 680, 3665)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10515)
[M::mem_pestat] mean and std.dev: (2005.83, 2476.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13940)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 374, 926)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2394)
[M::mem_pestat] mean and std.dev: (477.49, 391.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3128)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 13, #reads = 1109578 mem = 536878321 peak = 815497216
[M::process] read 755458 sequences (100000245 bp) in 4.141 CPU sec, 4.412 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 300732, 27, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 279, 751)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1927)
[M::mem_pestat] mean and std.dev: (383.00, 358.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2515)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 161, 219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 419)
[M::mem_pestat] mean and std.dev: (174.11, 73.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 519)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 288, 598)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1382)
[M::mem_pestat] mean and std.dev: (303.70, 217.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1774)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 486, 1797)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4983)
[M::mem_pestat] mean and std.dev: (878.22, 950.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6576)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 747244 reads in 224.749 CPU sec, 7.437 real sec
[M::process] read 755806 sequences (100000159 bp) in 2.694 CPU sec, 2.736 real sec...
[M::mem_process_seqs] Processed 747640 reads in 156.929 CPU sec, 5.212 real sec
sorting block 14, #reads = 1110600 mem = 536887924 peak = 815497216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 303621, 23, 19)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 280, 1751)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4927)
[M::mem_pestat] mean and std.dev: (982.39, 1331.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6515)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 156, 211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 403)
[M::mem_pestat] mean and std.dev: (168.10, 69.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 499)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 646, 1326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3638)
[M::mem_pestat] mean and std.dev: (658.00, 661.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4794)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 294, 962)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2626)
[M::mem_pestat] mean and std.dev: (468.53, 508.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3458)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 755496 sequences (100000150 bp) in 3.301 CPU sec, 3.437 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 303998, 15, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 215, 495)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1213)
[M::mem_pestat] mean and std.dev: (325.24, 252.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1572)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 156, 211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 403)
[M::mem_pestat] mean and std.dev: (168.03, 69.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 499)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (60, 151, 842)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2406)
[M::mem_pestat] mean and std.dev: (164.08, 213.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3188)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 204, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (211.88, 102.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 754972 sequences (100000107 bp) in 2.660 CPU sec, 2.659 real sec...
[M::mem_process_seqs] Processed 755458 reads in 227.076 CPU sec, 7.465 real sec
[M::mem_process_seqs] Processed 755806 reads in 151.979 CPU sec, 4.876 real sec
sorting block 15, #reads = 1111330 mem = 536879756 peak = 815497216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 304392, 19, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 220, 503)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1205)
[M::mem_pestat] mean and std.dev: (326.38, 235.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1556)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 156, 212)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 406)
[M::mem_pestat] mean and std.dev: (168.52, 70.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 503)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 166, 460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1114)
[M::mem_pestat] mean and std.dev: (283.28, 274.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1441)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 307, 1119)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2947)
[M::mem_pestat] mean and std.dev: (463.05, 393.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3861)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 755016 sequences (100000050 bp) in 3.286 CPU sec, 3.415 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 304238, 27, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 235, 563)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1367)
[M::mem_pestat] mean and std.dev: (309.29, 242.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1769)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 156, 213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 407)
[M::mem_pestat] mean and std.dev: (169.40, 71.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 504)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 893, 2031)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5551)
[M::mem_pestat] mean and std.dev: (1242.48, 1448.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7311)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 269, 1067)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2791)
[M::mem_pestat] mean and std.dev: (505.81, 439.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3653)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 754544 sequences (100000087 bp) in 2.300 CPU sec, 2.291 real sec...
[M::mem_process_seqs] Processed 755496 reads in 218.029 CPU sec, 6.996 real sec
sorting block 16, #reads = 1117752 mem = 536880283 peak = 833556480
[M::mem_process_seqs] Processed 754972 reads in 145.930 CPU sec, 4.648 real sec
sorting block 17, #reads = 1120138 mem = 536878163 peak = 836464640
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 304247, 29, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 209, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1036)
[M::mem_pestat] mean and std.dev: (247.77, 155.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1333)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 156, 212)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 406)
[M::mem_pestat] mean and std.dev: (169.12, 70.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 503)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 706, 2198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6296)
[M::mem_pestat] mean and std.dev: (1001.11, 1099.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8345)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 275, 1424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3970)
[M::mem_pestat] mean and std.dev: (696.86, 832.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5243)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 753442 sequences (100000196 bp) in 3.472 CPU sec, 3.601 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 303563, 22, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 423, 811)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1963)
[M::mem_pestat] mean and std.dev: (557.73, 410.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2539)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 156, 213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 407)
[M::mem_pestat] mean and std.dev: (169.51, 71.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 504)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 381, 992)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2636)
[M::mem_pestat] mean and std.dev: (430.84, 361.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3458)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 292, 565)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1369)
[M::mem_pestat] mean and std.dev: (357.00, 282.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1771)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 755016 reads in 218.739 CPU sec, 6.972 real sec
[M::process] read 753392 sequences (100000201 bp) in 2.781 CPU sec, 2.794 real sec...
[M::mem_process_seqs] Processed 754544 reads in 150.566 CPU sec, 4.789 real sec
sorting block 18, #reads = 1121306 mem = 536886038 peak = 836464640
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 302982, 13, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 350, 744)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1874)
[M::mem_pestat] mean and std.dev: (491.55, 419.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2439)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 157, 214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 410)
[M::mem_pestat] mean and std.dev: (170.20, 71.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 508)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 247, 1672)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4714)
[M::mem_pestat] mean and std.dev: (718.92, 743.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6235)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 239, 948)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2524)
[M::mem_pestat] mean and std.dev: (524.39, 529.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3312)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 752286 sequences (100000068 bp) in 3.663 CPU sec, 3.808 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 303538, 34, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 250, 607)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1445)
[M::mem_pestat] mean and std.dev: (307.23, 227.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1864)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 157, 215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 413)
[M::mem_pestat] mean and std.dev: (170.71, 72.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 512)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (71, 248, 915)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2603)
[M::mem_pestat] mean and std.dev: (468.31, 501.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3447)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (140, 241, 965)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2615)
[M::mem_pestat] mean and std.dev: (472.70, 520.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3440)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 753442 reads in 218.992 CPU sec, 6.991 real sec
[M::process] read 751690 sequences (100000216 bp) in 2.999 CPU sec, 3.059 real sec...
[M::mem_process_seqs] Processed 753392 reads in 150.359 CPU sec, 4.930 real sec
sorting block 19, #reads = 1117744 mem = 536882450 peak = 836464640
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 303293, 31, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 305, 1142)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3132)
[M::mem_pestat] mean and std.dev: (670.39, 725.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4127)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 414)
[M::mem_pestat] mean and std.dev: (171.28, 72.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 513)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (359, 969, 2368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6386)
[M::mem_pestat] mean and std.dev: (1774.80, 2094.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10154)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 245, 826)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2202)
[M::mem_pestat] mean and std.dev: (436.79, 462.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2890)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 20, #reads = 1116770 mem = 536877776 peak = 878211072
[M::process] read 750960 sequences (100000005 bp) in 3.258 CPU sec, 3.396 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 302668, 22, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 241, 950)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2520)
[M::mem_pestat] mean and std.dev: (579.08, 579.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3305)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 414)
[M::mem_pestat] mean and std.dev: (171.75, 72.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 513)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (91, 435, 1555)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4483)
[M::mem_pestat] mean and std.dev: (938.10, 1246.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5947)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 267, 760)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1906)
[M::mem_pestat] mean and std.dev: (377.03, 323.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2479)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 752286 reads in 209.842 CPU sec, 6.856 real sec
[M::process] read 751256 sequences (100000004 bp) in 2.855 CPU sec, 2.883 real sec...
[M::mem_process_seqs] Processed 751690 reads in 145.766 CPU sec, 4.623 real sec
sorting block 21, #reads = 1119175 mem = 536878150 peak = 878211072
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 302654, 24, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (111, 169, 561)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1461)
[M::mem_pestat] mean and std.dev: (273.31, 265.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1911)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 417)
[M::mem_pestat] mean and std.dev: (172.29, 72.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 517)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (292, 611, 2869)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8023)
[M::mem_pestat] mean and std.dev: (1686.75, 2101.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10600)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 563, 1614)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4434)
[M::mem_pestat] mean and std.dev: (880.60, 1028.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5844)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 751140 sequences (100000244 bp) in 4.009 CPU sec, 4.306 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 302934, 29, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 604, 1527)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4249)
[M::mem_pestat] mean and std.dev: (800.14, 752.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5610)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 417)
[M::mem_pestat] mean and std.dev: (172.38, 72.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 517)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 293, 1236)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3410)
[M::mem_pestat] mean and std.dev: (601.70, 740.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4497)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 288, 1167)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3013)
[M::mem_pestat] mean and std.dev: (616.94, 684.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3936)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 750960 reads in 212.526 CPU sec, 6.795 real sec
[M::mem_process_seqs] Processed 751256 reads in 150.140 CPU sec, 4.769 real sec
[M::process] read 751042 sequences (100000155 bp) in 3.390 CPU sec, 3.532 real sec...
sorting block 22, #reads = 1116887 mem = 536884218 peak = 878211072
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 303166, 11, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 248, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1080)
[M::mem_pestat] mean and std.dev: (245.11, 158.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1389)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 420)
[M::mem_pestat] mean and std.dev: (172.78, 73.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 521)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (23, 74, 602)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1760)
[M::mem_pestat] mean and std.dev: (209.70, 236.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2339)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 407, 715)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1841)
[M::mem_pestat] mean and std.dev: (477.00, 428.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2404)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 749766 sequences (100000095 bp) in 3.463 CPU sec, 3.623 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 302856, 15, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 257, 717)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1841)
[M::mem_pestat] mean and std.dev: (327.23, 263.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2403)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 417)
[M::mem_pestat] mean and std.dev: (172.38, 72.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 517)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (610, 1053, 2692)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6856)
[M::mem_pestat] mean and std.dev: (1486.53, 1445.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8938)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 271, 999)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2649)
[M::mem_pestat] mean and std.dev: (539.16, 560.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3474)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 751140 reads in 209.928 CPU sec, 6.694 real sec
[M::mem_process_seqs] Processed 751042 reads in 149.686 CPU sec, 4.753 real sec
sorting block 23, #reads = 1116285 mem = 536883802 peak = 878211072
[M::process] read 748480 sequences (100000086 bp) in 3.222 CPU sec, 3.334 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 302067, 31, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 371, 875)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2325)
[M::mem_pestat] mean and std.dev: (515.76, 471.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3050)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 418)
[M::mem_pestat] mean and std.dev: (173.39, 73.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 518)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 321, 1241)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3427)
[M::mem_pestat] mean and std.dev: (618.87, 720.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4520)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 215, 574)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1370)
[M::mem_pestat] mean and std.dev: (327.27, 284.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1768)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 24, #reads = 1115596 mem = 536881837 peak = 907259904
[M::process] read 748026 sequences (100000049 bp) in 3.728 CPU sec, 3.905 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 301879, 30, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 405, 919)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2433)
[M::mem_pestat] mean and std.dev: (516.74, 432.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3190)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 161, 220)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 424)
[M::mem_pestat] mean and std.dev: (174.40, 73.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 526)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 302, 893)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2377)
[M::mem_pestat] mean and std.dev: (359.48, 415.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3119)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 472, 1411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3889)
[M::mem_pestat] mean and std.dev: (974.00, 1138.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5530)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 749766 reads in 214.040 CPU sec, 6.839 real sec
[M::mem_process_seqs] Processed 748480 reads in 149.905 CPU sec, 4.761 real sec
[M::process] read 747876 sequences (100000215 bp) in 3.528 CPU sec, 3.709 real sec...
sorting block 25, #reads = 1114842 mem = 536885339 peak = 907259904
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 301353, 29, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 432, 753)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1947)
[M::mem_pestat] mean and std.dev: (478.33, 373.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2544)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 161, 220)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 424)
[M::mem_pestat] mean and std.dev: (174.83, 74.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 526)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 369, 1219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3365)
[M::mem_pestat] mean and std.dev: (604.67, 703.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4438)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 399, 1335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3617)
[M::mem_pestat] mean and std.dev: (645.73, 572.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4758)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 747806 sequences (100000117 bp) in 3.154 CPU sec, 3.327 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 300735, 27, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 444, 976)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2628)
[M::mem_pestat] mean and std.dev: (545.35, 481.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3454)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 161, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 418)
[M::mem_pestat] mean and std.dev: (173.70, 72.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 518)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 527, 831)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2127)
[M::mem_pestat] mean and std.dev: (495.21, 437.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2775)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 254, 1462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4088)
[M::mem_pestat] mean and std.dev: (631.00, 674.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5401)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 747084 sequences (100000111 bp) in 2.047 CPU sec, 2.051 real sec...
[M::mem_process_seqs] Processed 748026 reads in 219.784 CPU sec, 7.018 real sec
[M::mem_process_seqs] Processed 747876 reads in 152.346 CPU sec, 5.073 real sec
sorting block 26, #reads = 1114077 mem = 536879434 peak = 907259904
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 301110, 23, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 269, 1129)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3089)
[M::mem_pestat] mean and std.dev: (612.56, 748.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4069)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 161, 219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 419)
[M::mem_pestat] mean and std.dev: (174.24, 73.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 519)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (340, 927, 2051)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5473)
[M::mem_pestat] mean and std.dev: (1034.52, 953.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7184)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 366, 779)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1953)
[M::mem_pestat] mean and std.dev: (475.57, 420.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2540)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 747032 sequences (100000242 bp) in 3.749 CPU sec, 3.992 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 300792, 21, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 349, 1123)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3057)
[M::mem_pestat] mean and std.dev: (684.71, 745.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4024)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 161, 220)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 422)
[M::mem_pestat] mean and std.dev: (174.79, 73.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 523)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 632, 1504)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4132)
[M::mem_pestat] mean and std.dev: (764.63, 847.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5446)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 406, 777)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1919)
[M::mem_pestat] mean and std.dev: (539.79, 440.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2490)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 747806 reads in 214.170 CPU sec, 7.042 real sec
[M::process] read 747484 sequences (100000171 bp) in 3.103 CPU sec, 3.195 real sec...
[M::mem_process_seqs] Processed 747084 reads in 149.061 CPU sec, 4.725 real sec
sorting block 27, #reads = 1111929 mem = 536877605 peak = 907259904
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 300858, 18, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 388, 1420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3950)
[M::mem_pestat] mean and std.dev: (880.24, 942.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5215)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 162, 220)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 422)
[M::mem_pestat] mean and std.dev: (174.96, 73.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 523)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 1076, 1861)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5199)
[M::mem_pestat] mean and std.dev: (1076.29, 1067.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6868)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 352, 1039)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2775)
[M::mem_pestat] mean and std.dev: (520.39, 476.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3643)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 28, #reads = 1110755 mem = 536879156 peak = 907259904
[M::process] read 747450 sequences (100000073 bp) in 3.988 CPU sec, 4.230 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 300937, 23, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 314, 1055)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2877)
[M::mem_pestat] mean and std.dev: (555.41, 626.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3788)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 161, 220)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 422)
[M::mem_pestat] mean and std.dev: (174.45, 73.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 523)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 904, 1095)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2801)
[M::mem_pestat] mean and std.dev: (747.45, 620.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3654)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 401, 711)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1769)
[M::mem_pestat] mean and std.dev: (439.72, 316.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2298)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 747032 reads in 218.055 CPU sec, 7.203 real sec
[M::mem_process_seqs] Processed 747484 reads in 151.422 CPU sec, 4.799 real sec
[M::process] read 751824 sequences (100000264 bp) in 3.343 CPU sec, 3.481 real sec...
sorting block 29, #reads = 1112729 mem = 536883820 peak = 907259904
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 300963, 19, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 370, 974)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2526)
[M::mem_pestat] mean and std.dev: (551.26, 496.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3302)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 161, 220)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 422)
[M::mem_pestat] mean and std.dev: (174.85, 73.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 523)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 622, 3415)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9703)
[M::mem_pestat] mean and std.dev: (2113.26, 2911.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13760)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 250, 768)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1974)
[M::mem_pestat] mean and std.dev: (502.27, 565.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2765)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 757154 sequences (100000167 bp) in 3.428 CPU sec, 3.568 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 302661, 25, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 294, 950)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2528)
[M::mem_pestat] mean and std.dev: (553.81, 563.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3317)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 411)
[M::mem_pestat] mean and std.dev: (170.95, 71.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 509)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (120, 241, 1418)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4014)
[M::mem_pestat] mean and std.dev: (781.28, 980.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5312)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 422, 1370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3642)
[M::mem_pestat] mean and std.dev: (706.91, 699.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4778)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 747450 reads in 222.276 CPU sec, 7.070 real sec
[M::process] read 754926 sequences (100000075 bp) in 2.921 CPU sec, 2.971 real sec...
[M::mem_process_seqs] Processed 751824 reads in 157.211 CPU sec, 5.064 real sec
sorting block 30, #reads = 1111375 mem = 536881025 peak = 907259904
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 304107, 37, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 305, 713)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1763)
[M::mem_pestat] mean and std.dev: (390.78, 339.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2288)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 155, 209)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 397)
[M::mem_pestat] mean and std.dev: (166.89, 68.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 491)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (129, 228, 1202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3348)
[M::mem_pestat] mean and std.dev: (547.89, 711.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4421)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 199, 524)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1280)
[M::mem_pestat] mean and std.dev: (351.65, 312.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1658)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 753904 sequences (100000087 bp) in 3.720 CPU sec, 3.908 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 303783, 31, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 231, 636)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1538)
[M::mem_pestat] mean and std.dev: (370.97, 361.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1989)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 156, 212)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 404)
[M::mem_pestat] mean and std.dev: (168.72, 70.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 500)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 592, 2122)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6044)
[M::mem_pestat] mean and std.dev: (1239.24, 1574.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8005)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 354, 1795)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4909)
[M::mem_pestat] mean and std.dev: (1050.60, 1249.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6466)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 757154 reads in 223.735 CPU sec, 7.230 real sec
sorting block 31, #reads = 1113217 mem = 536883395 peak = 907259904
[M::mem_process_seqs] Processed 754926 reads in 153.289 CPU sec, 4.855 real sec
[M::process] read 753418 sequences (100000126 bp) in 3.097 CPU sec, 3.187 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 303433, 15, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 229, 825)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2151)
[M::mem_pestat] mean and std.dev: (419.18, 360.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2814)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 157, 214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 410)
[M::mem_pestat] mean and std.dev: (170.17, 71.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 508)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (87, 146, 638)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1740)
[M::mem_pestat] mean and std.dev: (268.00, 381.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2291)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 314, 1521)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4201)
[M::mem_pestat] mean and std.dev: (678.85, 841.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5541)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 32, #reads = 1118510 mem = 536885311 peak = 907259904
[M::process] read 753364 sequences (100000162 bp) in 3.329 CPU sec, 3.452 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 303382, 19, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 263, 392)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 836)
[M::mem_pestat] mean and std.dev: (230.18, 94.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1058)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 157, 214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 410)
[M::mem_pestat] mean and std.dev: (170.51, 71.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 508)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (70, 397, 716)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2008)
[M::mem_pestat] mean and std.dev: (384.94, 355.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2654)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 286, 1250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3420)
[M::mem_pestat] mean and std.dev: (711.02, 802.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4505)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 753904 reads in 216.197 CPU sec, 6.912 real sec
[M::mem_process_seqs] Processed 753418 reads in 149.659 CPU sec, 4.743 real sec
[M::process] read 752474 sequences (100000107 bp) in 2.956 CPU sec, 3.020 real sec...
sorting block 33, #reads = 1118800 mem = 536883392 peak = 907259904
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 303237, 29, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 334, 635)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1529)
[M::mem_pestat] mean and std.dev: (449.88, 370.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1976)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 157, 214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 410)
[M::mem_pestat] mean and std.dev: (170.47, 71.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 508)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 218, 484)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1154)
[M::mem_pestat] mean and std.dev: (227.46, 159.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1489)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 274, 414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 808)
[M::mem_pestat] mean and std.dev: (262.74, 105.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1005)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 752708 sequences (100000097 bp) in 3.634 CPU sec, 3.769 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 302738, 24, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 463, 1601)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4325)
[M::mem_pestat] mean and std.dev: (869.79, 913.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5687)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 411)
[M::mem_pestat] mean and std.dev: (171.20, 72.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 509)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (624, 1196, 3352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8808)
[M::mem_pestat] mean and std.dev: (2186.25, 2244.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11536)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 260, 946)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2464)
[M::mem_pestat] mean and std.dev: (617.68, 662.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3269)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 753364 reads in 211.723 CPU sec, 6.766 real sec
[M::process] read 752546 sequences (100000131 bp) in 2.681 CPU sec, 2.704 real sec...
[M::mem_process_seqs] Processed 752474 reads in 146.209 CPU sec, 4.890 real sec
sorting block 34, #reads = 1119092 mem = 536885591 peak = 907259904
sorting block 35, #reads = 1117905 mem = 536879531 peak = 907259904
[M::process] read 751432 sequences (100000066 bp) in 3.578 CPU sec, 3.789 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 303413, 20, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 286, 851)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2181)
[M::mem_pestat] mean and std.dev: (415.96, 337.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2846)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 158, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 416)
[M::mem_pestat] mean and std.dev: (171.47, 72.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 516)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (55, 588, 1860)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5470)
[M::mem_pestat] mean and std.dev: (760.00, 851.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7275)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 275, 833)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2123)
[M::mem_pestat] mean and std.dev: (421.59, 365.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2768)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 752546 reads in 120.703 CPU sec, 3.810 real sec
[M::process] read 751652 sequences (100000151 bp) in 2.632 CPU sec, 2.683 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 303577, 20, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 303, 908)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2312)
[M::mem_pestat] mean and std.dev: (414.75, 437.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3014)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 158, 215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 413)
[M::mem_pestat] mean and std.dev: (170.92, 71.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 512)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (276, 525, 714)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1590)
[M::mem_pestat] mean and std.dev: (453.39, 320.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2028)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 242, 743)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1837)
[M::mem_pestat] mean and std.dev: (368.89, 277.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2384)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 302955, 20, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (267, 456, 1488)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3930)
[M::mem_pestat] mean and std.dev: (809.89, 853.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5151)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 417)
[M::mem_pestat] mean and std.dev: (172.31, 72.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 517)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (713, 1082, 1363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2663)
[M::mem_pestat] mean and std.dev: (950.11, 528.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3313)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 261, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 742)
[M::mem_pestat] mean and std.dev: (250.46, 108.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 938)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 752708 reads in 331.926 CPU sec, 10.826 real sec
[M::mem_process_seqs] Processed 751432 reads in 175.594 CPU sec, 5.595 real sec
sorting block 36, #reads = 1116588 mem = 536877264 peak = 907259904
[M::process] read 751042 sequences (100000294 bp) in 3.678 CPU sec, 3.827 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 302340, 21, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 338, 901)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2325)
[M::mem_pestat] mean and std.dev: (385.05, 320.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3037)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 414)
[M::mem_pestat] mean and std.dev: (171.64, 72.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 513)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 414, 899)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2411)
[M::mem_pestat] mean and std.dev: (485.21, 421.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3167)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 244, 826)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2164)
[M::mem_pestat] mean and std.dev: (329.20, 313.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2833)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 37, #reads = 1117443 mem = 536878181 peak = 907259904
[M::process] read 749744 sequences (100000060 bp) in 3.826 CPU sec, 4.111 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 302765, 23, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 409, 1969)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5589)
[M::mem_pestat] mean and std.dev: (1298.90, 1603.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7712)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 414)
[M::mem_pestat] mean and std.dev: (171.89, 72.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 513)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (125, 343, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1160)
[M::mem_pestat] mean and std.dev: (311.55, 272.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1505)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 231, 535)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1233)
[M::mem_pestat] mean and std.dev: (333.35, 267.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1582)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 751652 reads in 217.315 CPU sec, 6.956 real sec
[M::mem_process_seqs] Processed 751042 reads in 150.888 CPU sec, 4.791 real sec
[M::process] read 748416 sequences (100000153 bp) in 3.054 CPU sec, 3.187 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 302352, 20, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 346, 992)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2670)
[M::mem_pestat] mean and std.dev: (542.60, 545.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3509)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 418)
[M::mem_pestat] mean and std.dev: (173.27, 73.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 518)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (261, 907, 1485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3933)
[M::mem_pestat] mean and std.dev: (936.22, 830.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5157)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (141, 233, 1347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3759)
[M::mem_pestat] mean and std.dev: (657.81, 896.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4965)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 38, #reads = 1117015 mem = 536881963 peak = 907259904
[M::process] read 748094 sequences (100000049 bp) in 3.495 CPU sec, 3.629 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 301492, 26, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 314, 818)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2164)
[M::mem_pestat] mean and std.dev: (486.68, 438.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2837)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 161, 220)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 424)
[M::mem_pestat] mean and std.dev: (174.59, 74.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 526)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (368, 1179, 1759)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4541)
[M::mem_pestat] mean and std.dev: (1229.28, 1001.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5932)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (141, 215, 1219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3375)
[M::mem_pestat] mean and std.dev: (507.38, 532.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4453)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 749744 reads in 214.937 CPU sec, 6.846 real sec
[M::mem_process_seqs] Processed 748416 reads in 145.288 CPU sec, 4.598 real sec
[M::process] read 747234 sequences (100000151 bp) in 3.124 CPU sec, 3.233 real sec...
sorting block 39, #reads = 1116504 mem = 536877432 peak = 907259904
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 301317, 20, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 445, 982)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2652)
[M::mem_pestat] mean and std.dev: (583.71, 605.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3487)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 161, 220)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 424)
[M::mem_pestat] mean and std.dev: (174.54, 73.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 526)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 573, 2902)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8396)
[M::mem_pestat] mean and std.dev: (1812.90, 2303.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11143)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 285, 694)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1772)
[M::mem_pestat] mean and std.dev: (376.05, 381.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2311)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 747524 sequences (100000211 bp) in 3.454 CPU sec, 3.692 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 300879, 18, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 349, 978)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2614)
[M::mem_pestat] mean and std.dev: (572.87, 555.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3432)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 161, 220)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 422)
[M::mem_pestat] mean and std.dev: (174.49, 73.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 523)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 363, 833)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2073)
[M::mem_pestat] mean and std.dev: (470.76, 374.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2693)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 466, 704)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1692)
[M::mem_pestat] mean and std.dev: (468.58, 364.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2186)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 748094 reads in 215.523 CPU sec, 6.899 real sec
[M::mem_process_seqs] Processed 747234 reads in 150.627 CPU sec, 4.776 real sec
sorting block 40, #reads = 1115178 mem = 536889893 peak = 907259904
[M::process] read 748136 sequences (100000046 bp) in 2.611 CPU sec, 2.670 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 300764, 22, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 478, 1559)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4297)
[M::mem_pestat] mean and std.dev: (648.88, 677.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5666)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 161, 219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 419)
[M::mem_pestat] mean and std.dev: (174.05, 72.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 519)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (85, 344, 729)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2017)
[M::mem_pestat] mean and std.dev: (443.95, 476.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2661)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (140, 279, 1099)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3017)
[M::mem_pestat] mean and std.dev: (612.86, 610.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3976)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 41, #reads = 1113469 mem = 536888189 peak = 907259904
[M::process] read 748526 sequences (100000078 bp) in 4.028 CPU sec, 4.251 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 301181, 24, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 334, 1435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3971)
[M::mem_pestat] mean and std.dev: (808.43, 941.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5239)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 161, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 418)
[M::mem_pestat] mean and std.dev: (173.59, 72.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 518)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (274, 559, 899)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2149)
[M::mem_pestat] mean and std.dev: (549.50, 376.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2774)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 495, 1485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4129)
[M::mem_pestat] mean and std.dev: (653.69, 735.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5451)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 747524 reads in 214.869 CPU sec, 6.853 real sec
[M::mem_process_seqs] Processed 748136 reads in 150.209 CPU sec, 4.765 real sec
[M::process] read 747002 sequences (100000193 bp) in 3.209 CPU sec, 3.329 real sec...
sorting block 42, #reads = 1112156 mem = 536881736 peak = 907259904
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 301602, 24, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 300, 877)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2257)
[M::mem_pestat] mean and std.dev: (445.28, 396.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2947)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 418)
[M::mem_pestat] mean and std.dev: (173.34, 72.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 518)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 301, 1537)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4327)
[M::mem_pestat] mean and std.dev: (816.04, 1160.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5722)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 213, 895)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2363)
[M::mem_pestat] mean and std.dev: (502.45, 558.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3097)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 747366 sequences (100000003 bp) in 3.302 CPU sec, 3.404 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 301009, 34, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 462, 1431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3841)
[M::mem_pestat] mean and std.dev: (770.46, 749.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5046)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 162, 220)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 422)
[M::mem_pestat] mean and std.dev: (174.79, 73.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 523)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 469, 875)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2287)
[M::mem_pestat] mean and std.dev: (514.33, 486.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2993)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 366, 845)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2231)
[M::mem_pestat] mean and std.dev: (484.51, 457.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2924)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 748526 reads in 216.366 CPU sec, 6.892 real sec
[M::process] read 747576 sequences (100000163 bp) in 2.784 CPU sec, 2.824 real sec...
[M::mem_process_seqs] Processed 747002 reads in 155.778 CPU sec, 4.931 real sec
sorting block 43, #reads = 1113567 mem = 536878550 peak = 907259904
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 301190, 32, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 580, 1637)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4607)
[M::mem_pestat] mean and std.dev: (751.83, 650.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6092)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 161, 220)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 422)
[M::mem_pestat] mean and std.dev: (174.91, 73.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 523)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (274, 703, 2227)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6133)
[M::mem_pestat] mean and std.dev: (734.92, 801.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8086)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 258, 660)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1666)
[M::mem_pestat] mean and std.dev: (331.97, 349.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2169)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 747846 sequences (100000157 bp) in 3.536 CPU sec, 3.737 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 301461, 30, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 301, 528)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1248)
[M::mem_pestat] mean and std.dev: (276.74, 177.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1608)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 161, 220)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 422)
[M::mem_pestat] mean and std.dev: (174.88, 74.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 523)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 351, 760)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1840)
[M::mem_pestat] mean and std.dev: (492.86, 446.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2380)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 277, 796)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2062)
[M::mem_pestat] mean and std.dev: (445.81, 428.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2695)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 747366 reads in 220.020 CPU sec, 7.028 real sec
[M::mem_process_seqs] Processed 747576 reads in 152.532 CPU sec, 4.834 real sec
sorting block 44, #reads = 1113031 mem = 536879024 peak = 907259904
[M::process] read 754022 sequences (100000154 bp) in 3.065 CPU sec, 3.145 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 301155, 23, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 500, 1125)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3021)
[M::mem_pestat] mean and std.dev: (759.77, 761.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3969)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 161, 219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 419)
[M::mem_pestat] mean and std.dev: (174.23, 73.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 519)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (101, 227, 1649)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4745)
[M::mem_pestat] mean and std.dev: (744.86, 1006.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6293)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 256, 388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 828)
[M::mem_pestat] mean and std.dev: (265.85, 147.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1048)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 45, #reads = 1111044 mem = 536880831 peak = 907259904
[M::process] read 757328 sequences (100000020 bp) in 3.117 CPU sec, 3.191 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 302700, 26, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 225, 1151)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3147)
[M::mem_pestat] mean and std.dev: (539.26, 636.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4145)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 157, 213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 407)
[M::mem_pestat] mean and std.dev: (169.58, 70.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 504)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (87, 519, 1609)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4653)
[M::mem_pestat] mean and std.dev: (795.60, 982.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6175)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 258, 553)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1309)
[M::mem_pestat] mean and std.dev: (319.48, 273.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1687)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 754774 sequences (100000046 bp) in 2.480 CPU sec, 2.483 real sec...
[M::mem_process_seqs] Processed 747846 reads in 227.668 CPU sec, 7.271 real sec
[M::mem_process_seqs] Processed 754022 reads in 158.510 CPU sec, 5.099 real sec
sorting block 46, #reads = 1110011 mem = 536878282 peak = 907259904
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 304412, 27, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 469, 1585)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4483)
[M::mem_pestat] mean and std.dev: (798.79, 875.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5932)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 154, 208)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 394)
[M::mem_pestat] mean and std.dev: (166.08, 67.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 487)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (480, 601, 1164)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2532)
[M::mem_pestat] mean and std.dev: (866.56, 493.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3216)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 298, 811)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2071)
[M::mem_pestat] mean and std.dev: (485.44, 513.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2701)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 754092 sequences (100000221 bp) in 2.848 CPU sec, 2.967 real sec...
[M::process] read 753830 sequences (100000054 bp) in 1.970 CPU sec, 1.972 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 303437, 27, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 222, 1093)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2913)
[M::mem_pestat] mean and std.dev: (398.78, 365.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3823)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 156, 211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 401)
[M::mem_pestat] mean and std.dev: (168.59, 69.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 496)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (266, 711, 1739)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4685)
[M::mem_pestat] mean and std.dev: (678.32, 635.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6158)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 318, 833)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2159)
[M::mem_pestat] mean and std.dev: (524.51, 474.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2822)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 757328 reads in 211.259 CPU sec, 6.790 real sec
[M::mem_process_seqs] Processed 754774 reads in 141.147 CPU sec, 4.666 real sec
sorting block 47, #reads = 1115956 mem = 536877498 peak = 907259904
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 303557, 23, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 339, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1080)
[M::mem_pestat] mean and std.dev: (282.42, 213.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1394)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 157, 213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 407)
[M::mem_pestat] mean and std.dev: (169.62, 70.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 504)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (293, 528, 1663)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4403)
[M::mem_pestat] mean and std.dev: (789.05, 691.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5773)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 372, 1235)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3297)
[M::mem_pestat] mean and std.dev: (747.69, 747.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4328)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 753334 sequences (100000195 bp) in 3.112 CPU sec, 3.200 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 303233, 25, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 321, 770)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1922)
[M::mem_pestat] mean and std.dev: (386.00, 349.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2498)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 157, 213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 407)
[M::mem_pestat] mean and std.dev: (169.62, 70.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 504)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 475, 999)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2631)
[M::mem_pestat] mean and std.dev: (563.21, 501.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3447)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 340, 1185)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3265)
[M::mem_pestat] mean and std.dev: (533.79, 598.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4305)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 752246 sequences (100000133 bp) in 2.390 CPU sec, 2.385 real sec...
[M::mem_process_seqs] Processed 754092 reads in 206.598 CPU sec, 6.737 real sec
sorting block 48, #reads = 1118041 mem = 536877771 peak = 942632960
[M::mem_process_seqs] Processed 753830 reads in 138.643 CPU sec, 4.421 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 303200, 20, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (124, 205, 603)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1561)
[M::mem_pestat] mean and std.dev: (373.11, 344.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2040)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 157, 214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 410)
[M::mem_pestat] mean and std.dev: (170.26, 71.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 508)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 695, 5933)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 17361)
[M::mem_pestat] mean and std.dev: (2693.75, 3680.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 23075)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 234, 565)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1355)
[M::mem_pestat] mean and std.dev: (297.27, 195.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1750)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 49, #reads = 1117742 mem = 536879080 peak = 947306496
[M::process] read 752008 sequences (100000042 bp) in 3.087 CPU sec, 3.283 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 302681, 23, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 217, 622)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1496)
[M::mem_pestat] mean and std.dev: (381.84, 295.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1933)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 414)
[M::mem_pestat] mean and std.dev: (171.42, 72.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 513)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (115, 419, 1026)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2848)
[M::mem_pestat] mean and std.dev: (555.09, 480.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3759)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 290, 394)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 866)
[M::mem_pestat] mean and std.dev: (254.75, 116.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1102)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 751560 sequences (100000081 bp) in 1.990 CPU sec, 1.985 real sec...
[M::mem_process_seqs] Processed 753334 reads in 199.727 CPU sec, 6.372 real sec
[M::mem_process_seqs] Processed 752246 reads in 137.013 CPU sec, 4.362 real sec
sorting block 50, #reads = 1117928 mem = 536880441 peak = 947306496
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 302799, 17, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 252, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1009)
[M::mem_pestat] mean and std.dev: (303.53, 207.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1286)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 414)
[M::mem_pestat] mean and std.dev: (171.58, 72.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 513)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 509, 1929)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5359)
[M::mem_pestat] mean and std.dev: (707.20, 705.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7074)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 319, 638)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1574)
[M::mem_pestat] mean and std.dev: (409.39, 308.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2042)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 750774 sequences (100000114 bp) in 3.017 CPU sec, 3.114 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 302739, 21, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 360, 948)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2492)
[M::mem_pestat] mean and std.dev: (414.25, 396.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3264)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 414)
[M::mem_pestat] mean and std.dev: (171.60, 72.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 513)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (272, 508, 1814)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4898)
[M::mem_pestat] mean and std.dev: (1254.90, 1448.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7049)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 298, 946)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2490)
[M::mem_pestat] mean and std.dev: (637.00, 676.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3342)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 751598 sequences (100000022 bp) in 2.360 CPU sec, 2.360 real sec...
[M::mem_process_seqs] Processed 752008 reads in 201.042 CPU sec, 6.398 real sec
[M::mem_process_seqs] Processed 751560 reads in 135.682 CPU sec, 4.407 real sec
sorting block 51, #reads = 1116022 mem = 536879590 peak = 947306496
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 302741, 26, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 346, 1205)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3343)
[M::mem_pestat] mean and std.dev: (619.18, 734.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4412)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 417)
[M::mem_pestat] mean and std.dev: (172.44, 72.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 517)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (98, 462, 1213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3443)
[M::mem_pestat] mean and std.dev: (689.12, 808.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4558)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 328, 1196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3128)
[M::mem_pestat] mean and std.dev: (644.51, 711.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4094)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 750628 sequences (100000190 bp) in 2.917 CPU sec, 2.973 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 302298, 17, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 460, 1029)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2809)
[M::mem_pestat] mean and std.dev: (553.68, 561.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3699)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 414)
[M::mem_pestat] mean and std.dev: (171.50, 72.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 513)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 555, 1665)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4691)
[M::mem_pestat] mean and std.dev: (773.81, 722.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6204)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 211, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 737)
[M::mem_pestat] mean and std.dev: (237.50, 139.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 930)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 748810 sequences (100000044 bp) in 2.480 CPU sec, 2.478 real sec...
[M::mem_process_seqs] Processed 750774 reads in 199.948 CPU sec, 6.432 real sec
sorting block 52, #reads = 1116061 mem = 536882100 peak = 947306496
[M::mem_process_seqs] Processed 751598 reads in 135.153 CPU sec, 4.280 real sec
sorting block 53, #reads = 1114925 mem = 536880643 peak = 947306496
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 302482, 23, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 286, 1105)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2959)
[M::mem_pestat] mean and std.dev: (592.82, 685.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3886)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 160, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 420)
[M::mem_pestat] mean and std.dev: (173.00, 73.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 521)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 952, 2741)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7849)
[M::mem_pestat] mean and std.dev: (1406.91, 1462.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10403)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 369, 1168)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3090)
[M::mem_pestat] mean and std.dev: (778.14, 847.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4167)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 747158 sequences (100000056 bp) in 3.553 CPU sec, 3.730 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 301644, 18, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 231, 955)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2535)
[M::mem_pestat] mean and std.dev: (540.76, 591.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3325)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 161, 219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 421)
[M::mem_pestat] mean and std.dev: (173.89, 73.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 522)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (126, 496, 588)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1512)
[M::mem_pestat] mean and std.dev: (298.33, 234.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1974)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 269, 424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 868)
[M::mem_pestat] mean and std.dev: (284.36, 145.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1090)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 750628 reads in 194.122 CPU sec, 6.299 real sec
[M::mem_process_seqs] Processed 748810 reads in 134.615 CPU sec, 4.259 real sec
[M::process] read 746304 sequences (100000100 bp) in 2.869 CPU sec, 2.951 real sec...
sorting block 54, #reads = 1116298 mem = 536882564 peak = 947306496
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 301175, 28, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 264, 956)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2500)
[M::mem_pestat] mean and std.dev: (537.36, 558.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3272)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 162, 221)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 425)
[M::mem_pestat] mean and std.dev: (175.25, 74.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 527)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (301, 864, 1254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3160)
[M::mem_pestat] mean and std.dev: (793.68, 611.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4113)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 239, 1042)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2808)
[M::mem_pestat] mean and std.dev: (419.26, 348.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3691)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 746524 sequences (100000007 bp) in 2.688 CPU sec, 2.768 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 300990, 25, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 372, 1579)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4315)
[M::mem_pestat] mean and std.dev: (651.68, 880.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5683)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 162, 221)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 425)
[M::mem_pestat] mean and std.dev: (175.62, 74.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 527)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 476, 905)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2309)
[M::mem_pestat] mean and std.dev: (461.05, 357.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3011)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 261, 580)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1410)
[M::mem_pestat] mean and std.dev: (311.84, 229.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1825)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 746748 sequences (100000206 bp) in 1.860 CPU sec, 1.859 real sec...
[M::mem_process_seqs] Processed 747158 reads in 198.652 CPU sec, 6.341 real sec
[M::mem_process_seqs] Processed 746304 reads in 134.819 CPU sec, 4.313 real sec
sorting block 55, #reads = 1114421 mem = 536878990 peak = 947306496
sorting block 56, #reads = 1112168 mem = 536881180 peak = 984985600
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 300733, 23, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 274, 654)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1594)
[M::mem_pestat] mean and std.dev: (388.87, 311.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2064)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 162, 220)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 422)
[M::mem_pestat] mean and std.dev: (175.15, 73.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 523)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (315, 849, 1784)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4722)
[M::mem_pestat] mean and std.dev: (1093.48, 1033.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6191)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 372, 1432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3848)
[M::mem_pestat] mean and std.dev: (896.40, 1014.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5056)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 746792 sequences (100000191 bp) in 3.068 CPU sec, 3.141 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 300758, 14, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 301, 977)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2595)
[M::mem_pestat] mean and std.dev: (532.68, 571.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3404)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 162, 220)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 422)
[M::mem_pestat] mean and std.dev: (175.08, 73.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 523)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (418, 471, 573)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (108, 883)
[M::mem_pestat] mean and std.dev: (439.50, 129.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1038)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 241, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1000)
[M::mem_pestat] mean and std.dev: (296.13, 204.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1277)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 747480 sequences (100000172 bp) in 1.959 CPU sec, 1.955 real sec...
[M::mem_process_seqs] Processed 746524 reads in 196.409 CPU sec, 6.291 real sec
[M::mem_process_seqs] Processed 746748 reads in 130.641 CPU sec, 4.216 real sec
sorting block 57, #reads = 1110901 mem = 536879062 peak = 984985600
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 301067, 16, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 303, 602)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1488)
[M::mem_pestat] mean and std.dev: (342.30, 279.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1931)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 162, 220)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 422)
[M::mem_pestat] mean and std.dev: (174.97, 73.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 523)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (371, 514, 920)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2018)
[M::mem_pestat] mean and std.dev: (637.07, 489.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2595)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 236, 380)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 820)
[M::mem_pestat] mean and std.dev: (246.72, 126.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1040)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 747248 sequences (100000204 bp) in 3.456 CPU sec, 3.673 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 301417, 16, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 244, 886)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2344)
[M::mem_pestat] mean and std.dev: (473.64, 467.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3073)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 161, 220)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 422)
[M::mem_pestat] mean and std.dev: (174.60, 73.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 523)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 760, 1499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4015)
[M::mem_pestat] mean and std.dev: (866.40, 854.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5273)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 308, 608)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1546)
[M::mem_pestat] mean and std.dev: (379.55, 342.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2015)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 746792 reads in 195.512 CPU sec, 6.281 real sec
[M::process] read 747282 sequences (100000080 bp) in 2.010 CPU sec, 2.017 real sec...
[M::mem_process_seqs] Processed 747480 reads in 136.816 CPU sec, 4.564 real sec
sorting block 58, #reads = 1112901 mem = 536880396 peak = 984985600
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 301113, 35, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 266, 870)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2322)
[M::mem_pestat] mean and std.dev: (411.67, 374.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3048)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 162, 220)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 422)
[M::mem_pestat] mean and std.dev: (174.67, 73.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 523)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 458, 1715)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4857)
[M::mem_pestat] mean and std.dev: (922.82, 1124.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6428)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 377, 1173)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3205)
[M::mem_pestat] mean and std.dev: (562.24, 635.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4221)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 747480 sequences (100000005 bp) in 3.295 CPU sec, 3.401 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 301766, 32, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 215, 935)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2491)
[M::mem_pestat] mean and std.dev: (488.46, 515.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3269)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 162, 221)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 425)
[M::mem_pestat] mean and std.dev: (175.20, 74.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 527)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 495, 893)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2351)
[M::mem_pestat] mean and std.dev: (496.64, 467.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3080)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 269, 503)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1205)
[M::mem_pestat] mean and std.dev: (259.42, 144.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1556)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 747144 sequences (100000067 bp) in 2.380 CPU sec, 2.384 real sec...
[M::mem_process_seqs] Processed 747248 reads in 200.236 CPU sec, 6.560 real sec
sorting block 59, #reads = 1113655 mem = 536879127 peak = 984985600
[M::mem_process_seqs] Processed 747282 reads in 135.944 CPU sec, 4.416 real sec
sorting block 60, #reads = 1113039 mem = 536880204 peak = 984985600
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 300790, 21, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 267, 1007)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2689)
[M::mem_pestat] mean and std.dev: (678.00, 770.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3762)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 161, 219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 419)
[M::mem_pestat] mean and std.dev: (174.24, 73.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 519)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (84, 340, 859)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2409)
[M::mem_pestat] mean and std.dev: (411.11, 511.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3184)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 379, 1028)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2656)
[M::mem_pestat] mean and std.dev: (518.27, 487.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3470)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 755890 sequences (100000257 bp) in 2.551 CPU sec, 2.627 real sec...
[M::process] read 759734 sequences (100000261 bp) in 1.950 CPU sec, 1.952 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 301132, 25, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 340, 839)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2209)
[M::mem_pestat] mean and std.dev: (471.79, 483.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2894)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 162, 221)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 425)
[M::mem_pestat] mean and std.dev: (175.29, 74.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 527)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 356, 753)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1895)
[M::mem_pestat] mean and std.dev: (448.48, 345.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2466)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 225, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 794)
[M::mem_pestat] mean and std.dev: (210.41, 113.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1004)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 747480 reads in 201.054 CPU sec, 6.514 real sec
[M::mem_process_seqs] Processed 747144 reads in 134.895 CPU sec, 4.358 real sec
sorting block 61, #reads = 1111031 mem = 536880004 peak = 984985600
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 303657, 25, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 618, 1782)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4834)
[M::mem_pestat] mean and std.dev: (873.44, 948.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6360)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 155, 210)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 400)
[M::mem_pestat] mean and std.dev: (167.50, 68.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 495)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (486, 1244, 2995)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8013)
[M::mem_pestat] mean and std.dev: (1587.52, 1604.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10522)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 247, 981)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2571)
[M::mem_pestat] mean and std.dev: (599.43, 703.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3414)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 759462 sequences (100000230 bp) in 2.844 CPU sec, 2.904 real sec...
[M::process] read 760152 sequences (100000137 bp) in 2.590 CPU sec, 2.590 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 304359, 23, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 518, 1338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3668)
[M::mem_pestat] mean and std.dev: (781.21, 827.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4833)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (114, 153, 205)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 387)
[M::mem_pestat] mean and std.dev: (164.01, 66.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 478)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (123, 428, 1244)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3486)
[M::mem_pestat] mean and std.dev: (573.95, 665.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4607)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 247, 769)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1993)
[M::mem_pestat] mean and std.dev: (450.65, 429.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2605)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 755890 reads in 219.444 CPU sec, 7.006 real sec
[M::mem_process_seqs] Processed 759734 reads in 147.418 CPU sec, 4.686 real sec
sorting block 62, #reads = 1110929 mem = 536879251 peak = 984985600
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 305379, 27, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 274, 924)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2432)
[M::mem_pestat] mean and std.dev: (401.90, 352.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3186)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (114, 153, 206)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 390)
[M::mem_pestat] mean and std.dev: (164.47, 66.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 482)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (110, 381, 1476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4208)
[M::mem_pestat] mean and std.dev: (730.38, 953.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5574)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 323, 1876)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5310)
[M::mem_pestat] mean and std.dev: (1106.11, 1323.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7027)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 757904 sequences (100000047 bp) in 3.565 CPU sec, 3.750 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 305592, 14, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 242, 702)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1794)
[M::mem_pestat] mean and std.dev: (360.38, 327.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2340)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (114, 152, 205)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 387)
[M::mem_pestat] mean and std.dev: (163.81, 66.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 478)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 1463, 2604)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7382)
[M::mem_pestat] mean and std.dev: (1787.57, 1862.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9771)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 249, 894)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2390)
[M::mem_pestat] mean and std.dev: (419.90, 409.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3138)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 756740 sequences (100000053 bp) in 2.020 CPU sec, 2.017 real sec...
[M::mem_process_seqs] Processed 759462 reads in 205.372 CPU sec, 6.512 real sec
sorting block 63, #reads = 1114562 mem = 536880876 peak = 984985600
[M::mem_process_seqs] Processed 760152 reads in 140.197 CPU sec, 4.449 real sec
sorting block 64, #reads = 1118471 mem = 536877556 peak = 987148288
[M::process] read 756470 sequences (100000112 bp) in 2.518 CPU sec, 2.611 real sec...
[M::process] read 755544 sequences (100000096 bp) in 2.490 CPU sec, 2.487 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 304157, 21, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 399, 744)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1858)
[M::mem_pestat] mean and std.dev: (418.12, 289.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2415)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 155, 209)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 397)
[M::mem_pestat] mean and std.dev: (166.90, 68.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 491)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 680, 1538)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4194)
[M::mem_pestat] mean and std.dev: (962.75, 1004.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5522)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 312, 718)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1714)
[M::mem_pestat] mean and std.dev: (502.07, 428.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2218)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 756740 reads in 113.429 CPU sec, 3.670 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 305029, 38, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 480, 1221)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3301)
[M::mem_pestat] mean and std.dev: (798.61, 818.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4341)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 154, 207)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 391)
[M::mem_pestat] mean and std.dev: (165.58, 67.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 483)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 1074, 1984)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5556)
[M::mem_pestat] mean and std.dev: (1107.03, 992.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7342)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 421, 1161)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3029)
[M::mem_pestat] mean and std.dev: (637.66, 567.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3963)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 304429, 7, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 506, 1202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3332)
[M::mem_pestat] mean and std.dev: (653.88, 627.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4397)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 155, 209)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 397)
[M::mem_pestat] mean and std.dev: (166.81, 68.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 491)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 375, 1042)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2792)
[M::mem_pestat] mean and std.dev: (583.03, 586.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3667)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 755368 sequences (100000142 bp) in 2.095 CPU sec, 2.104 real sec...
[M::mem_process_seqs] Processed 757904 reads in 318.436 CPU sec, 10.307 real sec
sorting block 65, #reads = 1119569 mem = 536879371 peak = 987148288
[M::mem_process_seqs] Processed 756470 reads in 166.339 CPU sec, 5.619 real sec
sorting block 66, #reads = 1119407 mem = 536880044 peak = 1004793856
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 304332, 18, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 372, 476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1042)
[M::mem_pestat] mean and std.dev: (375.70, 239.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1334)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 155, 210)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 400)
[M::mem_pestat] mean and std.dev: (167.64, 69.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 495)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 418, 1283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3551)
[M::mem_pestat] mean and std.dev: (680.89, 671.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4685)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 217, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 772)
[M::mem_pestat] mean and std.dev: (225.37, 117.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 981)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 754960 sequences (100000157 bp) in 3.098 CPU sec, 3.173 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 304183, 26, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 441, 1371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3775)
[M::mem_pestat] mean and std.dev: (550.69, 470.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4977)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 155, 211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 403)
[M::mem_pestat] mean and std.dev: (167.99, 69.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 499)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 737, 1750)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4982)
[M::mem_pestat] mean and std.dev: (1006.56, 1088.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6598)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 320, 1175)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3181)
[M::mem_pestat] mean and std.dev: (530.67, 504.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4184)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 755568 sequences (100000162 bp) in 2.510 CPU sec, 2.504 real sec...
[M::mem_process_seqs] Processed 755544 reads in 207.702 CPU sec, 6.798 real sec
[M::mem_process_seqs] Processed 755368 reads in 137.806 CPU sec, 4.462 real sec
sorting block 67, #reads = 1118540 mem = 536877300 peak = 1004793856
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 303745, 18, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 338, 670)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1614)
[M::mem_pestat] mean and std.dev: (379.50, 296.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2086)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 156, 211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 401)
[M::mem_pestat] mean and std.dev: (168.18, 69.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 496)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (405, 772, 2778)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7524)
[M::mem_pestat] mean and std.dev: (1182.50, 1337.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9897)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 245, 410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 902)
[M::mem_pestat] mean and std.dev: (270.27, 173.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1148)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 755182 sequences (100000035 bp) in 2.979 CPU sec, 3.083 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 304307, 21, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 305, 878)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2260)
[M::mem_pestat] mean and std.dev: (539.80, 493.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2951)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 155, 211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 403)
[M::mem_pestat] mean and std.dev: (168.19, 70.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 499)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (287, 590, 1585)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4181)
[M::mem_pestat] mean and std.dev: (833.57, 774.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5479)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 328, 865)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2241)
[M::mem_pestat] mean and std.dev: (591.03, 648.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3183)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 754484 sequences (100000023 bp) in 1.920 CPU sec, 1.914 real sec...
[M::mem_process_seqs] Processed 754960 reads in 203.989 CPU sec, 6.602 real sec
sorting block 68, #reads = 1118733 mem = 536879836 peak = 1004793856
[M::mem_process_seqs] Processed 755568 reads in 141.136 CPU sec, 4.504 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 304336, 21, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 323, 847)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2235)
[M::mem_pestat] mean and std.dev: (412.57, 402.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2929)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 156, 211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 403)
[M::mem_pestat] mean and std.dev: (168.20, 69.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 499)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (70, 230, 1403)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4069)
[M::mem_pestat] mean and std.dev: (600.47, 735.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5402)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 347, 1732)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4834)
[M::mem_pestat] mean and std.dev: (801.46, 874.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6385)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 754488 sequences (100000247 bp) in 2.733 CPU sec, 2.790 real sec...
[M::process] read 754104 sequences (100000136 bp) in 1.970 CPU sec, 1.971 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 303534, 20, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (121, 210, 950)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2608)
[M::mem_pestat] mean and std.dev: (419.00, 453.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3437)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 156, 212)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 404)
[M::mem_pestat] mean and std.dev: (168.83, 70.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 500)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (528, 1010, 1283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2793)
[M::mem_pestat] mean and std.dev: (892.05, 577.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3548)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 252, 1181)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3189)
[M::mem_pestat] mean and std.dev: (438.16, 454.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4193)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 755182 reads in 199.370 CPU sec, 6.344 real sec
sorting block 69, #reads = 1118102 mem = 536884430 peak = 1004793856
[M::mem_process_seqs] Processed 754484 reads in 136.290 CPU sec, 4.650 real sec
sorting block 70, #reads = 1116630 mem = 536878578 peak = 1009704960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 303851, 32, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 436, 1628)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4580)
[M::mem_pestat] mean and std.dev: (707.13, 773.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6056)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 156, 212)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 404)
[M::mem_pestat] mean and std.dev: (168.82, 70.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 500)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 410, 844)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2160)
[M::mem_pestat] mean and std.dev: (477.96, 368.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2818)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 263, 1065)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2897)
[M::mem_pestat] mean and std.dev: (559.25, 761.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3813)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 753350 sequences (100000108 bp) in 3.392 CPU sec, 3.612 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 303679, 18, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 330, 818)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2106)
[M::mem_pestat] mean and std.dev: (443.48, 410.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2750)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 156, 212)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 404)
[M::mem_pestat] mean and std.dev: (168.66, 69.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 500)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 288, 1127)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3071)
[M::mem_pestat] mean and std.dev: (659.06, 843.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4043)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 300, 1856)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5196)
[M::mem_pestat] mean and std.dev: (927.74, 1087.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6866)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 754488 reads in 194.098 CPU sec, 6.484 real sec
[M::mem_process_seqs] Processed 754104 reads in 133.342 CPU sec, 4.216 real sec
[M::process] read 752056 sequences (100000157 bp) in 3.065 CPU sec, 3.169 real sec...
sorting block 71, #reads = 1116210 mem = 536876304 peak = 1009704960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 302663, 24, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 261, 919)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2345)
[M::mem_pestat] mean and std.dev: (467.54, 499.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3058)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 157, 213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 407)
[M::mem_pestat] mean and std.dev: (169.93, 71.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 504)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (106, 578, 985)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2743)
[M::mem_pestat] mean and std.dev: (639.96, 652.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3622)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 888, 2619)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7465)
[M::mem_pestat] mean and std.dev: (963.06, 995.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9888)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 750964 sequences (100000150 bp) in 3.741 CPU sec, 3.849 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 302732, 22, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 215, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 972)
[M::mem_pestat] mean and std.dev: (267.18, 179.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1242)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 411)
[M::mem_pestat] mean and std.dev: (170.92, 71.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 509)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (88, 360, 1170)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3334)
[M::mem_pestat] mean and std.dev: (547.25, 568.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4416)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 256, 803)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2081)
[M::mem_pestat] mean and std.dev: (466.11, 452.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2720)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 753350 reads in 199.598 CPU sec, 6.385 real sec
[M::mem_process_seqs] Processed 752056 reads in 140.189 CPU sec, 4.435 real sec
sorting block 72, #reads = 1116788 mem = 536880239 peak = 1009704960
[M::process] read 749680 sequences (100000059 bp) in 3.015 CPU sec, 3.161 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 303007, 23, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (274, 503, 3112)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8788)
[M::mem_pestat] mean and std.dev: (1476.64, 1968.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11626)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 414)
[M::mem_pestat] mean and std.dev: (171.99, 72.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 513)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (281, 574, 1162)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2924)
[M::mem_pestat] mean and std.dev: (606.05, 616.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3805)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 173, 1836)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5222)
[M::mem_pestat] mean and std.dev: (736.66, 902.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6915)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 73, #reads = 1114990 mem = 536879171 peak = 1009704960
[M::process] read 749558 sequences (100000272 bp) in 2.990 CPU sec, 3.100 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 301574, 28, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 260, 890)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2290)
[M::mem_pestat] mean and std.dev: (434.92, 414.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2990)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 418)
[M::mem_pestat] mean and std.dev: (173.31, 73.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 518)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (40, 256, 1107)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3241)
[M::mem_pestat] mean and std.dev: (400.38, 431.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4308)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 357, 1265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3463)
[M::mem_pestat] mean and std.dev: (614.47, 578.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4562)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 750964 reads in 203.677 CPU sec, 6.497 real sec
[M::mem_process_seqs] Processed 749680 reads in 141.773 CPU sec, 4.481 real sec
[M::process] read 748712 sequences (100000209 bp) in 2.860 CPU sec, 2.950 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 302103, 22, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 253, 968)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2626)
[M::mem_pestat] mean and std.dev: (400.70, 393.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3455)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 418)
[M::mem_pestat] mean and std.dev: (172.93, 72.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 518)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 393, 623)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1603)
[M::mem_pestat] mean and std.dev: (363.47, 291.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2093)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 291, 420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 890)
[M::mem_pestat] mean and std.dev: (284.91, 156.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1125)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 74, #reads = 1111518 mem = 536889649 peak = 1009704960
[M::process] read 748952 sequences (100000110 bp) in 3.680 CPU sec, 3.855 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 301651, 23, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 347, 1533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4281)
[M::mem_pestat] mean and std.dev: (698.95, 790.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5655)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 161, 219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 421)
[M::mem_pestat] mean and std.dev: (173.86, 73.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 522)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 696, 2784)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7944)
[M::mem_pestat] mean and std.dev: (1271.70, 1269.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10524)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 241, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1080)
[M::mem_pestat] mean and std.dev: (246.53, 173.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1395)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 749558 reads in 198.969 CPU sec, 6.362 real sec
[M::mem_process_seqs] Processed 748712 reads in 138.874 CPU sec, 4.405 real sec
sorting block 75, #reads = 1112759 mem = 536879875 peak = 1009704960
[M::process] read 749336 sequences (100000045 bp) in 3.047 CPU sec, 3.140 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 301462, 23, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 243, 1114)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3036)
[M::mem_pestat] mean and std.dev: (541.93, 672.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3997)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 418)
[M::mem_pestat] mean and std.dev: (173.50, 73.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 518)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (360, 552, 780)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1620)
[M::mem_pestat] mean and std.dev: (588.27, 425.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2292)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 354, 1351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3619)
[M::mem_pestat] mean and std.dev: (606.97, 629.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4753)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 762322 sequences (100000165 bp) in 2.755 CPU sec, 2.834 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 301855, 28, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (125, 272, 808)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2174)
[M::mem_pestat] mean and std.dev: (418.89, 439.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2857)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 418)
[M::mem_pestat] mean and std.dev: (173.03, 72.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 518)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 623, 1314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3492)
[M::mem_pestat] mean and std.dev: (763.86, 584.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4581)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 272, 580)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1382)
[M::mem_pestat] mean and std.dev: (314.83, 198.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1783)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 764622 sequences (100000173 bp) in 2.010 CPU sec, 2.005 real sec...
[M::mem_process_seqs] Processed 748952 reads in 211.867 CPU sec, 6.753 real sec
sorting block 76, #reads = 1112455 mem = 536880085 peak = 1009704960
[M::mem_process_seqs] Processed 749336 reads in 147.707 CPU sec, 4.714 real sec
sorting block 77, #reads = 1111384 mem = 536877604 peak = 1087692800
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 305070, 22, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (121, 450, 1098)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3052)
[M::mem_pestat] mean and std.dev: (674.02, 677.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4029)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (113, 151, 203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 383)
[M::mem_pestat] mean and std.dev: (162.36, 65.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 473)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (130, 225, 716)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1888)
[M::mem_pestat] mean and std.dev: (353.00, 368.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2474)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 265, 502)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1144)
[M::mem_pestat] mean and std.dev: (309.09, 232.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1465)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 763900 sequences (100000209 bp) in 2.857 CPU sec, 2.933 real sec...
[M::process] read 762788 sequences (100000021 bp) in 2.120 CPU sec, 2.126 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 306445, 24, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (127, 167, 538)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1360)
[M::mem_pestat] mean and std.dev: (250.00, 231.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1771)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (112, 150, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 379)
[M::mem_pestat] mean and std.dev: (160.90, 64.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 468)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (297, 548, 1164)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2898)
[M::mem_pestat] mean and std.dev: (654.17, 508.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3765)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 322, 993)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2661)
[M::mem_pestat] mean and std.dev: (708.69, 858.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4144)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 762322 reads in 233.695 CPU sec, 7.437 real sec
[M::mem_process_seqs] Processed 764622 reads in 161.273 CPU sec, 5.152 real sec
sorting block 78, #reads = 1105777 mem = 536882527 peak = 1087692800
[M::process] read 761860 sequences (100000119 bp) in 2.795 CPU sec, 2.854 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 306194, 19, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 253, 485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1113)
[M::mem_pestat] mean and std.dev: (300.61, 198.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1427)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (113, 150, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (161.14, 64.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 465)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 1378, 4492)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13068)
[M::mem_pestat] mean and std.dev: (2303.37, 2597.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17356)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 366, 1022)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2710)
[M::mem_pestat] mean and std.dev: (591.52, 590.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3554)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 763900 reads in 134.368 CPU sec, 4.331 real sec
sorting block 79, #reads = 1110338 mem = 536882081 peak = 1087692800
[M::process] read 759244 sequences (100000060 bp) in 2.543 CPU sec, 2.716 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 306144, 14, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 258, 673)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1733)
[M::mem_pestat] mean and std.dev: (326.40, 280.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2263)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (113, 151, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (161.77, 65.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 469)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 899, 1886)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5304)
[M::mem_pestat] mean and std.dev: (1346.79, 1507.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7378)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 236, 520)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1214)
[M::mem_pestat] mean and std.dev: (280.38, 181.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1561)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 758542 sequences (100000276 bp) in 2.537 CPU sec, 2.544 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 305927, 26, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 402, 884)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2240)
[M::mem_pestat] mean and std.dev: (466.64, 408.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2918)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (113, 151, 203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 383)
[M::mem_pestat] mean and std.dev: (162.63, 65.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 473)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (109, 228, 1082)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3028)
[M::mem_pestat] mean and std.dev: (483.88, 586.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4001)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 271, 887)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2329)
[M::mem_pestat] mean and std.dev: (446.67, 415.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3050)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 762788 reads in 258.233 CPU sec, 8.266 real sec
[M::mem_process_seqs] Processed 761860 reads in 285.343 CPU sec, 9.283 real sec
sorting block 80, #reads = 1112183 mem = 536879652 peak = 1087692800
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 305123, 27, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 194, 269)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 533)
[M::mem_pestat] mean and std.dev: (187.95, 66.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 665)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (114, 153, 207)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 393)
[M::mem_pestat] mean and std.dev: (164.98, 67.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 486)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (118, 382, 1019)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2821)
[M::mem_pestat] mean and std.dev: (505.40, 512.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3722)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 233, 860)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2312)
[M::mem_pestat] mean and std.dev: (402.58, 448.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3038)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 756842 sequences (100000026 bp) in 3.310 CPU sec, 3.537 real sec...
[M::process] read 756030 sequences (100000189 bp) in 1.950 CPU sec, 1.950 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 305041, 18, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 215, 872)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2296)
[M::mem_pestat] mean and std.dev: (350.12, 360.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3008)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (114, 153, 207)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 393)
[M::mem_pestat] mean and std.dev: (165.13, 67.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 486)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 680, 1406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3910)
[M::mem_pestat] mean and std.dev: (1134.89, 1208.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5969)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 496, 1507)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4163)
[M::mem_pestat] mean and std.dev: (545.24, 601.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5491)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 759244 reads in 225.888 CPU sec, 7.313 real sec
sorting block 81, #reads = 1111857 mem = 536878398 peak = 1087692800
[M::mem_process_seqs] Processed 758542 reads in 150.810 CPU sec, 4.834 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 304679, 25, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 388, 725)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1751)
[M::mem_pestat] mean and std.dev: (432.48, 362.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2264)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 154, 208)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 394)
[M::mem_pestat] mean and std.dev: (166.29, 68.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 487)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 619, 2703)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7667)
[M::mem_pestat] mean and std.dev: (1363.36, 1353.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10149)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 380, 1866)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5166)
[M::mem_pestat] mean and std.dev: (987.83, 1369.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6816)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 756410 sequences (100000211 bp) in 3.631 CPU sec, 3.831 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 303742, 26, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 239, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1130)
[M::mem_pestat] mean and std.dev: (245.74, 146.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1459)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 155, 209)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 397)
[M::mem_pestat] mean and std.dev: (167.05, 68.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 491)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 661, 1082)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2866)
[M::mem_pestat] mean and std.dev: (697.64, 629.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3758)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 609, 1520)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4182)
[M::mem_pestat] mean and std.dev: (584.60, 503.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5513)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 755152 sequences (100000036 bp) in 2.070 CPU sec, 2.061 real sec...
[M::mem_process_seqs] Processed 756842 reads in 209.598 CPU sec, 6.681 real sec
sorting block 82, #reads = 1113130 mem = 536879191 peak = 1087692800
[M::mem_process_seqs] Processed 756030 reads in 140.174 CPU sec, 4.616 real sec
sorting block 83, #reads = 1113137 mem = 536892886 peak = 1087692800
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 304666, 24, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 304, 840)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2174)
[M::mem_pestat] mean and std.dev: (420.89, 376.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2841)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 155, 209)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 397)
[M::mem_pestat] mean and std.dev: (166.83, 68.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 491)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (94, 318, 1066)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3010)
[M::mem_pestat] mean and std.dev: (637.96, 764.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3982)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (267, 375, 1803)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4875)
[M::mem_pestat] mean and std.dev: (825.31, 1018.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6411)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 755284 sequences (100000190 bp) in 3.397 CPU sec, 3.491 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 303953, 20, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 249, 495)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1183)
[M::mem_pestat] mean and std.dev: (326.27, 256.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1527)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 155, 210)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 400)
[M::mem_pestat] mean and std.dev: (167.75, 69.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 495)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (266, 635, 806)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1886)
[M::mem_pestat] mean and std.dev: (557.68, 393.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2426)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 205, 871)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2313)
[M::mem_pestat] mean and std.dev: (429.89, 420.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3034)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 754820 sequences (100000066 bp) in 2.510 CPU sec, 2.508 real sec...
[M::mem_process_seqs] Processed 756410 reads in 208.064 CPU sec, 6.763 real sec
[M::mem_process_seqs] Processed 755152 reads in 143.879 CPU sec, 4.619 real sec
sorting block 84, #reads = 1113828 mem = 536880196 peak = 1087692800
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 304032, 21, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 257, 673)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1719)
[M::mem_pestat] mean and std.dev: (317.71, 253.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2242)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 156, 211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 401)
[M::mem_pestat] mean and std.dev: (168.30, 69.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 496)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (77, 619, 2075)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6071)
[M::mem_pestat] mean and std.dev: (1091.95, 1189.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8069)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 239, 528)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1300)
[M::mem_pestat] mean and std.dev: (340.58, 264.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1686)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 753942 sequences (100000190 bp) in 3.045 CPU sec, 3.112 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 303681, 14, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 284, 666)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1680)
[M::mem_pestat] mean and std.dev: (356.56, 288.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2187)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 156, 210)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 398)
[M::mem_pestat] mean and std.dev: (167.90, 69.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 492)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (113, 316, 613)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1613)
[M::mem_pestat] mean and std.dev: (332.77, 241.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2113)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 337, 852)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2220)
[M::mem_pestat] mean and std.dev: (470.45, 468.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2904)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 753410 sequences (100000097 bp) in 2.527 CPU sec, 2.523 real sec...
[M::mem_process_seqs] Processed 755284 reads in 207.848 CPU sec, 6.664 real sec
sorting block 85, #reads = 1114185 mem = 536885881 peak = 1087692800
[M::mem_process_seqs] Processed 754820 reads in 137.879 CPU sec, 4.463 real sec
sorting block 86, #reads = 1115101 mem = 536882344 peak = 1087692800
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 303234, 31, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 411, 1130)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3120)
[M::mem_pestat] mean and std.dev: (616.11, 581.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4115)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 156, 211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 401)
[M::mem_pestat] mean and std.dev: (168.45, 69.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 496)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (254, 447, 1459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3869)
[M::mem_pestat] mean and std.dev: (883.10, 925.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5074)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 244, 1199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3207)
[M::mem_pestat] mean and std.dev: (519.09, 571.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4211)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 752226 sequences (100000252 bp) in 2.999 CPU sec, 3.068 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 303338, 43, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 373, 1251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3393)
[M::mem_pestat] mean and std.dev: (662.97, 721.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4464)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 157, 212)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 404)
[M::mem_pestat] mean and std.dev: (168.95, 69.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 500)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 241, 1565)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4311)
[M::mem_pestat] mean and std.dev: (849.27, 1025.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5684)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 182, 737)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1895)
[M::mem_pestat] mean and std.dev: (399.72, 443.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2474)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 753942 reads in 197.720 CPU sec, 6.362 real sec
[M::process] read 751262 sequences (100000188 bp) in 2.477 CPU sec, 2.482 real sec...
[M::mem_process_seqs] Processed 753410 reads in 133.773 CPU sec, 4.217 real sec
sorting block 87, #reads = 1113766 mem = 536879844 peak = 1087692800
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 303064, 32, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 337, 831)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2103)
[M::mem_pestat] mean and std.dev: (319.48, 214.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2739)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 408)
[M::mem_pestat] mean and std.dev: (170.30, 71.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 505)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 540, 1941)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5547)
[M::mem_pestat] mean and std.dev: (1136.55, 1297.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7350)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 290, 634)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1550)
[M::mem_pestat] mean and std.dev: (337.40, 282.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2008)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 750266 sequences (100000063 bp) in 2.685 CPU sec, 2.737 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 301995, 21, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 317, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 778)
[M::mem_pestat] mean and std.dev: (241.50, 125.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 987)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 411)
[M::mem_pestat] mean and std.dev: (171.08, 71.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 509)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (87, 569, 1290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3696)
[M::mem_pestat] mean and std.dev: (754.40, 804.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4899)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 215, 886)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2372)
[M::mem_pestat] mean and std.dev: (522.83, 612.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3115)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 749600 sequences (100000092 bp) in 2.440 CPU sec, 2.445 real sec...
[M::mem_process_seqs] Processed 752226 reads in 200.337 CPU sec, 6.425 real sec
sorting block 88, #reads = 1114770 mem = 536880747 peak = 1087692800
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 301830, 25, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 217, 1033)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2829)
[M::mem_pestat] mean and std.dev: (513.79, 584.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3727)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 411)
[M::mem_pestat] mean and std.dev: (171.38, 71.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 509)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (38, 234, 1460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4304)
[M::mem_pestat] mean and std.dev: (696.38, 938.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5726)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 294, 502)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1158)
[M::mem_pestat] mean and std.dev: (279.27, 168.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1486)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 750020 sequences (100000223 bp) in 2.498 CPU sec, 2.504 real sec...
[M::mem_process_seqs] Processed 750266 reads in 113.919 CPU sec, 3.743 real sec
[M::mem_process_seqs] Processed 751262 reads in 282.349 CPU sec, 9.110 real sec
sorting block 89, #reads = 1110773 mem = 536883342 peak = 1087692800
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 301859, 24, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 233, 957)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2497)
[M::mem_pestat] mean and std.dev: (469.79, 484.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3267)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 159, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 412)
[M::mem_pestat] mean and std.dev: (171.98, 71.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 510)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (119, 270, 796)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2150)
[M::mem_pestat] mean and std.dev: (456.13, 469.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2827)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 680, 1268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3414)
[M::mem_pestat] mean and std.dev: (523.75, 435.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4487)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 749840 sequences (100000241 bp) in 2.591 CPU sec, 2.755 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 301523, 33, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 294, 1997)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5723)
[M::mem_pestat] mean and std.dev: (1078.59, 1380.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7586)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 159, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 412)
[M::mem_pestat] mean and std.dev: (171.89, 71.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 510)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 467, 1065)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2843)
[M::mem_pestat] mean and std.dev: (646.70, 564.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3732)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 224, 656)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1668)
[M::mem_pestat] mean and std.dev: (356.32, 287.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2174)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 753944 sequences (100000126 bp) in 2.389 CPU sec, 2.389 real sec...
[M::mem_process_seqs] Processed 749600 reads in 229.867 CPU sec, 7.290 real sec
[M::mem_process_seqs] Processed 750020 reads in 139.435 CPU sec, 4.535 real sec
sorting block 90, #reads = 1112029 mem = 536881733 peak = 1087692800
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 301268, 22, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 223, 824)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2178)
[M::mem_pestat] mean and std.dev: (399.56, 453.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2855)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 159, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 412)
[M::mem_pestat] mean and std.dev: (171.81, 71.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 510)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 611, 2063)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5887)
[M::mem_pestat] mean and std.dev: (1149.50, 1158.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7799)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 463, 1431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3899)
[M::mem_pestat] mean and std.dev: (747.56, 803.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5133)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 760076 sequences (100000177 bp) in 3.358 CPU sec, 3.527 real sec...
[M::process] read 758436 sequences (100000050 bp) in 2.583 CPU sec, 2.597 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 302228, 27, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 305, 920)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2436)
[M::mem_pestat] mean and std.dev: (473.36, 415.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3194)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 156, 212)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 404)
[M::mem_pestat] mean and std.dev: (168.85, 69.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 500)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 206, 950)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2466)
[M::mem_pestat] mean and std.dev: (335.96, 324.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3224)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 233, 289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 529)
[M::mem_pestat] mean and std.dev: (215.92, 75.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 649)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 749840 reads in 235.491 CPU sec, 7.595 real sec
sorting block 91, #reads = 1110314 mem = 536878588 peak = 1087692800
[M::mem_process_seqs] Processed 753944 reads in 171.876 CPU sec, 5.664 real sec
sorting block 92, #reads = 1104234 mem = 536878361 peak = 1099874304
[M::process] read 756910 sequences (100000102 bp) in 2.622 CPU sec, 2.705 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 305164, 14, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (123, 163, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1098)
[M::mem_pestat] mean and std.dev: (255.62, 225.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1423)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (114, 153, 205)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 387)
[M::mem_pestat] mean and std.dev: (164.01, 66.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 478)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (104, 217, 541)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1415)
[M::mem_pestat] mean and std.dev: (252.92, 220.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1852)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 259, 914)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2420)
[M::mem_pestat] mean and std.dev: (479.57, 506.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3173)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 756440 sequences (100000057 bp) in 2.041 CPU sec, 2.048 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 304609, 28, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 251, 590)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1406)
[M::mem_pestat] mean and std.dev: (295.15, 232.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1814)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 154, 208)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 394)
[M::mem_pestat] mean and std.dev: (166.33, 68.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 487)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 628, 1395)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3893)
[M::mem_pestat] mean and std.dev: (845.36, 898.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5142)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 280, 769)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2001)
[M::mem_pestat] mean and std.dev: (461.23, 427.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2617)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 304907, 11, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 321, 706)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1822)
[M::mem_pestat] mean and std.dev: (480.28, 472.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2380)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (114, 154, 207)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 393)
[M::mem_pestat] mean and std.dev: (165.56, 67.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 486)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 478, 1674)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4620)
[M::mem_pestat] mean and std.dev: (934.00, 810.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6093)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 336, 1185)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3109)
[M::mem_pestat] mean and std.dev: (823.44, 879.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4340)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 760076 reads in 288.500 CPU sec, 9.441 real sec
[M::mem_process_seqs] Processed 756910 reads in 221.792 CPU sec, 7.156 real sec
[M::mem_process_seqs] Processed 758436 reads in 246.703 CPU sec, 7.998 real sec
sorting block 93, #reads = 1112294 mem = 536879093 peak = 1099874304
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 304998, 25, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 356, 713)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1819)
[M::mem_pestat] mean and std.dev: (338.78, 244.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2372)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 155, 210)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 400)
[M::mem_pestat] mean and std.dev: (167.27, 69.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 495)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (99, 525, 1024)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2874)
[M::mem_pestat] mean and std.dev: (696.68, 658.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3799)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 244, 519)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1237)
[M::mem_pestat] mean and std.dev: (303.69, 224.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1596)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 755088 sequences (100000038 bp) in 3.359 CPU sec, 3.525 real sec...
[M::mem_process_seqs] Processed 756440 reads in 111.271 CPU sec, 3.668 real sec
sorting block 94, #reads = 1117146 mem = 536880182 peak = 1099874304
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 303673, 29, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 322, 756)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1928)
[M::mem_pestat] mean and std.dev: (455.42, 452.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2514)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 156, 210)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 398)
[M::mem_pestat] mean and std.dev: (167.70, 68.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 492)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 383, 1784)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5014)
[M::mem_pestat] mean and std.dev: (798.75, 894.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6629)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 229, 1089)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3007)
[M::mem_pestat] mean and std.dev: (439.81, 478.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3966)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 755088 reads in 116.681 CPU sec, 3.845 real sec
[M::process] read 754826 sequences (100000154 bp) in 4.020 CPU sec, 4.330 real sec...
sorting block 95, #reads = 1117007 mem = 536881777 peak = 1099874304
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 303980, 13, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 287, 509)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1159)
[M::mem_pestat] mean and std.dev: (302.81, 169.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1484)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 156, 212)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 404)
[M::mem_pestat] mean and std.dev: (168.48, 69.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 500)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (81, 291, 1619)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4695)
[M::mem_pestat] mean and std.dev: (508.00, 676.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6233)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 183, 584)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1438)
[M::mem_pestat] mean and std.dev: (312.64, 257.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1865)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 754826 reads in 116.451 CPU sec, 3.805 real sec
[M::process] read 754008 sequences (100000246 bp) in 4.037 CPU sec, 4.361 real sec...
sorting block 96, #reads = 1117250 mem = 536880297 peak = 1099874304
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 303612, 22, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 371, 773)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1977)
[M::mem_pestat] mean and std.dev: (350.86, 233.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2579)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 156, 212)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 404)
[M::mem_pestat] mean and std.dev: (168.97, 70.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 500)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 582, 1341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3613)
[M::mem_pestat] mean and std.dev: (681.19, 669.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4749)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 485, 862)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2218)
[M::mem_pestat] mean and std.dev: (520.43, 425.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2896)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 754008 reads in 114.439 CPU sec, 3.708 real sec
[M::process] read 753018 sequences (100000165 bp) in 3.606 CPU sec, 3.854 real sec...
sorting block 97, #reads = 1116833 mem = 536886220 peak = 1099874304
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 303116, 16, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (113, 182, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (223.50, 143.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 889)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 157, 213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 405)
[M::mem_pestat] mean and std.dev: (169.75, 70.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 501)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (438, 503, 1489)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3591)
[M::mem_pestat] mean and std.dev: (568.77, 396.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4642)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 370, 1376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3812)
[M::mem_pestat] mean and std.dev: (777.76, 947.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5030)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 752932 sequences (100000178 bp) in 2.597 CPU sec, 2.800 real sec...
[M::mem_process_seqs] Processed 753018 reads in 103.297 CPU sec, 3.336 real sec
[M::process] read 753258 sequences (100000262 bp) in 2.701 CPU sec, 2.844 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 303425, 10, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 242, 716)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1784)
[M::mem_pestat] mean and std.dev: (461.08, 454.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2318)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 157, 213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 407)
[M::mem_pestat] mean and std.dev: (169.69, 70.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 504)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (284, 1406, 2802)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7838)
[M::mem_pestat] mean and std.dev: (1783.30, 1805.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10356)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 321, 492)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1078)
[M::mem_pestat] mean and std.dev: (308.31, 173.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1371)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 753212 sequences (100000101 bp) in 1.920 CPU sec, 1.920 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 303290, 36, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 400, 882)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2336)
[M::mem_pestat] mean and std.dev: (512.33, 437.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3063)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 157, 213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 407)
[M::mem_pestat] mean and std.dev: (169.52, 70.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 504)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 397, 796)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2122)
[M::mem_pestat] mean and std.dev: (437.67, 414.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2785)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 248, 1583)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4431)
[M::mem_pestat] mean and std.dev: (689.47, 898.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5855)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 752932 reads in 177.340 CPU sec, 5.578 real sec
[M::mem_process_seqs] Processed 753258 reads in 122.881 CPU sec, 3.868 real sec
[M::process] read 753934 sequences (100000091 bp) in 2.378 CPU sec, 2.446 real sec...
sorting block 98, #reads = 1115134 mem = 536876421 peak = 1099874304
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 303450, 14, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 280, 595)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1431)
[M::mem_pestat] mean and std.dev: (375.37, 263.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1849)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 157, 212)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 404)
[M::mem_pestat] mean and std.dev: (169.17, 69.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 500)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 622, 1059)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2867)
[M::mem_pestat] mean and std.dev: (601.85, 528.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3771)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 353, 1077)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2861)
[M::mem_pestat] mean and std.dev: (597.00, 624.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3753)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 99, #reads = 1116978 mem = 536879467 peak = 1099874304
[M::process] read 752478 sequences (100000117 bp) in 3.961 CPU sec, 4.165 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 303600, 21, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (128, 178, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1073)
[M::mem_pestat] mean and std.dev: (259.87, 215.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1388)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 157, 212)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 404)
[M::mem_pestat] mean and std.dev: (168.99, 70.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 500)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (84, 409, 850)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2382)
[M::mem_pestat] mean and std.dev: (311.00, 244.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3148)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 258, 460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 988)
[M::mem_pestat] mean and std.dev: (261.84, 117.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1252)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 753212 reads in 196.395 CPU sec, 6.287 real sec
[M::mem_process_seqs] Processed 753934 reads in 139.751 CPU sec, 4.431 real sec
[M::process] read 751058 sequences (100000104 bp) in 3.172 CPU sec, 3.407 real sec...
sorting block 100, #reads = 1115004 mem = 536878752 peak = 1099874304
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 303163, 19, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 346, 931)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2467)
[M::mem_pestat] mean and std.dev: (465.42, 468.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3235)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 405)
[M::mem_pestat] mean and std.dev: (169.79, 70.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 501)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (485, 977, 1757)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4301)
[M::mem_pestat] mean and std.dev: (970.88, 898.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5573)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 456, 1219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3283)
[M::mem_pestat] mean and std.dev: (666.79, 736.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4315)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 751112 sequences (100000254 bp) in 2.630 CPU sec, 2.704 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 302299, 17, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 270, 1187)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3173)
[M::mem_pestat] mean and std.dev: (614.50, 611.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4166)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 411)
[M::mem_pestat] mean and std.dev: (171.02, 71.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 509)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 358, 840)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2140)
[M::mem_pestat] mean and std.dev: (405.67, 365.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2790)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 304, 639)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1531)
[M::mem_pestat] mean and std.dev: (340.77, 223.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1977)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 752478 reads in 200.700 CPU sec, 6.387 real sec
[M::process] read 750464 sequences (100000205 bp) in 2.503 CPU sec, 2.540 real sec...
[M::mem_process_seqs] Processed 751058 reads in 138.118 CPU sec, 4.359 real sec
sorting block 101, #reads = 1115989 mem = 536879268 peak = 1099874304
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 302924, 31, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 194, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 663)
[M::mem_pestat] mean and std.dev: (197.52, 88.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 831)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 411)
[M::mem_pestat] mean and std.dev: (171.37, 71.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 509)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (79, 388, 695)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1927)
[M::mem_pestat] mean and std.dev: (400.86, 402.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2543)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 218, 804)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2126)
[M::mem_pestat] mean and std.dev: (351.95, 331.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2787)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 750804 sequences (100000039 bp) in 3.840 CPU sec, 4.098 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 302030, 16, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 367, 584)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1396)
[M::mem_pestat] mean and std.dev: (347.30, 229.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1802)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 414)
[M::mem_pestat] mean and std.dev: (171.85, 71.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 513)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 742, 972)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2608)
[M::mem_pestat] mean and std.dev: (542.20, 496.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3426)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 381, 1191)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3143)
[M::mem_pestat] mean and std.dev: (609.33, 617.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4119)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 751112 reads in 197.662 CPU sec, 6.322 real sec
sorting block 102, #reads = 1114121 mem = 536882113 peak = 1099874304
[M::mem_process_seqs] Processed 750464 reads in 139.833 CPU sec, 4.420 real sec
[M::process] read 749956 sequences (100000047 bp) in 2.987 CPU sec, 3.131 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 302715, 34, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 597, 1302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3524)
[M::mem_pestat] mean and std.dev: (757.54, 690.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4635)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 411)
[M::mem_pestat] mean and std.dev: (171.02, 71.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 509)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 428, 1674)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4736)
[M::mem_pestat] mean and std.dev: (900.44, 1132.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6267)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 457, 1437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3923)
[M::mem_pestat] mean and std.dev: (728.30, 763.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5166)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 103, #reads = 1113501 mem = 536887386 peak = 1099874304
[M::process] read 749152 sequences (100000189 bp) in 3.191 CPU sec, 3.415 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 301930, 38, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 334, 1194)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3258)
[M::mem_pestat] mean and std.dev: (687.77, 765.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4290)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 159, 215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 409)
[M::mem_pestat] mean and std.dev: (171.47, 70.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 506)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (356, 650, 1509)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3815)
[M::mem_pestat] mean and std.dev: (873.81, 751.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4968)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 262, 735)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1825)
[M::mem_pestat] mean and std.dev: (371.72, 355.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2370)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 750804 reads in 202.032 CPU sec, 6.427 real sec
[M::process] read 749326 sequences (100000125 bp) in 2.055 CPU sec, 2.073 real sec...
[M::mem_process_seqs] Processed 749956 reads in 134.370 CPU sec, 4.249 real sec
sorting block 104, #reads = 1113503 mem = 536876691 peak = 1099874304
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 301550, 29, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 309, 514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1196)
[M::mem_pestat] mean and std.dev: (313.31, 239.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1537)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 415)
[M::mem_pestat] mean and std.dev: (172.57, 71.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 514)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (112, 298, 1528)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4360)
[M::mem_pestat] mean and std.dev: (711.26, 1023.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5776)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 229, 598)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1486)
[M::mem_pestat] mean and std.dev: (339.06, 303.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1930)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 749218 sequences (100000253 bp) in 3.100 CPU sec, 3.197 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 301834, 20, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 573, 1137)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3089)
[M::mem_pestat] mean and std.dev: (594.10, 573.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4065)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 412)
[M::mem_pestat] mean and std.dev: (172.25, 71.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 510)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (110, 585, 1051)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2933)
[M::mem_pestat] mean and std.dev: (668.21, 778.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3874)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 241, 1111)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3007)
[M::mem_pestat] mean and std.dev: (549.25, 622.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3955)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 749152 reads in 189.246 CPU sec, 5.999 real sec
[M::process] read 749504 sequences (100000135 bp) in 2.491 CPU sec, 2.505 real sec...
[M::mem_process_seqs] Processed 749326 reads in 132.852 CPU sec, 4.195 real sec
sorting block 105, #reads = 1111965 mem = 536882354 peak = 1099874304
[M::process] read 759386 sequences (100000152 bp) in 3.229 CPU sec, 3.350 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 301016, 19, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 259, 691)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1763)
[M::mem_pestat] mean and std.dev: (369.40, 355.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2299)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 412)
[M::mem_pestat] mean and std.dev: (172.12, 71.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 510)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 483, 794)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2036)
[M::mem_pestat] mean and std.dev: (455.35, 385.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2657)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 464, 828)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2148)
[M::mem_pestat] mean and std.dev: (526.89, 464.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2808)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 767196 sequences (100000092 bp) in 2.060 CPU sec, 2.055 real sec...
[M::mem_process_seqs] Processed 749504 reads in 113.827 CPU sec, 3.594 real sec
sorting block 106, #reads = 1110487 mem = 536881503 peak = 1099874304
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 301660, 22, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 379, 976)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2580)
[M::mem_pestat] mean and std.dev: (528.08, 460.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3382)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 159, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 412)
[M::mem_pestat] mean and std.dev: (172.00, 71.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 510)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (327, 776, 1278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3180)
[M::mem_pestat] mean and std.dev: (839.29, 694.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4131)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 255, 625)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1443)
[M::mem_pestat] mean and std.dev: (336.70, 251.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1852)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 303583, 18, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 235, 605)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1517)
[M::mem_pestat] mean and std.dev: (367.33, 290.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1973)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (114, 153, 205)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 387)
[M::mem_pestat] mean and std.dev: (164.04, 66.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 478)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (65, 465, 716)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2018)
[M::mem_pestat] mean and std.dev: (534.12, 601.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2940)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 321, 1158)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3174)
[M::mem_pestat] mean and std.dev: (580.88, 700.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4182)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 761756 sequences (100000041 bp) in 2.151 CPU sec, 2.157 real sec...
[M::mem_process_seqs] Processed 749218 reads in 319.294 CPU sec, 10.136 real sec
sorting block 107, #reads = 1105885 mem = 536882754 peak = 1121968128
[M::mem_process_seqs] Processed 759386 reads in 175.390 CPU sec, 5.624 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 307122, 25, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 290, 717)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1883)
[M::mem_pestat] mean and std.dev: (418.38, 483.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2466)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 372)
[M::mem_pestat] mean and std.dev: (158.95, 63.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 459)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 475, 1754)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4876)
[M::mem_pestat] mean and std.dev: (809.78, 858.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6437)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 278, 638)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1568)
[M::mem_pestat] mean and std.dev: (371.26, 307.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2033)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 760424 sequences (100000260 bp) in 2.895 CPU sec, 3.000 real sec...
[M::process] read 759024 sequences (100000102 bp) in 2.190 CPU sec, 2.190 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 305501, 26, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 279, 1137)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3097)
[M::mem_pestat] mean and std.dev: (577.03, 636.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4077)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (113, 151, 204)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 386)
[M::mem_pestat] mean and std.dev: (162.82, 66.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 477)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 841, 1363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3681)
[M::mem_pestat] mean and std.dev: (748.04, 550.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4840)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 350, 862)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2176)
[M::mem_pestat] mean and std.dev: (511.07, 480.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2833)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 767196 reads in 197.686 CPU sec, 6.268 real sec
sorting block 108, #reads = 1101915 mem = 536882659 peak = 1121968128
[M::mem_process_seqs] Processed 761756 reads in 135.110 CPU sec, 4.299 real sec
sorting block 109, #reads = 1109609 mem = 536877918 peak = 1121968128
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 305466, 24, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 233, 607)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1509)
[M::mem_pestat] mean and std.dev: (337.83, 297.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1960)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (114, 152, 205)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 387)
[M::mem_pestat] mean and std.dev: (163.57, 66.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 478)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 687, 1570)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4302)
[M::mem_pestat] mean and std.dev: (767.38, 792.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5668)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 384, 1287)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3433)
[M::mem_pestat] mean and std.dev: (692.97, 582.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4506)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 756906 sequences (100000135 bp) in 3.161 CPU sec, 3.263 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 304905, 17, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 222, 811)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2129)
[M::mem_pestat] mean and std.dev: (326.35, 360.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2788)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (114, 153, 207)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 393)
[M::mem_pestat] mean and std.dev: (165.18, 67.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 486)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 340, 2225)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6233)
[M::mem_pestat] mean and std.dev: (1073.59, 1311.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8237)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 232, 616)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1550)
[M::mem_pestat] mean and std.dev: (320.33, 242.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2017)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 756522 sequences (100000151 bp) in 2.106 CPU sec, 2.115 real sec...
[M::mem_process_seqs] Processed 760424 reads in 191.397 CPU sec, 6.070 real sec
[M::mem_process_seqs] Processed 759024 reads in 128.679 CPU sec, 4.084 real sec
sorting block 110, #reads = 1110716 mem = 536878403 peak = 1121968128
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 304789, 21, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 217, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 623)
[M::mem_pestat] mean and std.dev: (196.24, 91.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 783)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 155, 209)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 397)
[M::mem_pestat] mean and std.dev: (166.56, 68.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 491)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 541, 721)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1845)
[M::mem_pestat] mean and std.dev: (483.71, 360.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2407)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 198, 425)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1017)
[M::mem_pestat] mean and std.dev: (217.29, 150.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1313)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 755286 sequences (100000156 bp) in 3.417 CPU sec, 3.611 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 304106, 19, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 380, 1113)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3017)
[M::mem_pestat] mean and std.dev: (526.97, 641.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3969)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 155, 210)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 400)
[M::mem_pestat] mean and std.dev: (167.31, 69.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 495)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 468, 2046)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5682)
[M::mem_pestat] mean and std.dev: (1301.05, 1813.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8556)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 350, 732)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1850)
[M::mem_pestat] mean and std.dev: (443.81, 413.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2409)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 756906 reads in 185.915 CPU sec, 5.883 real sec
[M::process] read 754034 sequences (100000028 bp) in 2.137 CPU sec, 2.141 real sec...
sorting block 111, #reads = 1113076 mem = 536880516 peak = 1121968128
[M::mem_process_seqs] Processed 756522 reads in 128.472 CPU sec, 4.075 real sec
sorting block 112, #reads = 1111429 mem = 536879316 peak = 1121968128
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 303409, 35, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 335, 1146)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3140)
[M::mem_pestat] mean and std.dev: (501.59, 533.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4137)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 156, 211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 403)
[M::mem_pestat] mean and std.dev: (168.27, 69.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 499)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (74, 296, 1095)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3137)
[M::mem_pestat] mean and std.dev: (678.91, 793.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4158)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 298, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1001)
[M::mem_pestat] mean and std.dev: (288.34, 149.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1273)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 754276 sequences (100000091 bp) in 2.885 CPU sec, 2.981 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 303551, 19, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 410, 673)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1667)
[M::mem_pestat] mean and std.dev: (432.02, 342.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2164)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 157, 213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 407)
[M::mem_pestat] mean and std.dev: (169.50, 70.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 504)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (484, 1077, 2683)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7081)
[M::mem_pestat] mean and std.dev: (1527.79, 1412.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9280)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 273, 856)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2210)
[M::mem_pestat] mean and std.dev: (526.83, 479.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2887)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 751774 sequences (100000041 bp) in 2.450 CPU sec, 2.446 real sec...
[M::mem_process_seqs] Processed 755286 reads in 191.074 CPU sec, 6.045 real sec
[M::mem_process_seqs] Processed 754034 reads in 132.364 CPU sec, 4.187 real sec
sorting block 113, #reads = 1112015 mem = 536896479 peak = 1121968128
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 303476, 23, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 435, 889)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2397)
[M::mem_pestat] mean and std.dev: (537.89, 500.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3151)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 156, 212)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 404)
[M::mem_pestat] mean and std.dev: (168.73, 70.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 500)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (99, 225, 1020)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2862)
[M::mem_pestat] mean and std.dev: (570.57, 818.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3847)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 260, 943)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2475)
[M::mem_pestat] mean and std.dev: (434.10, 410.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3241)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 751656 sequences (100000161 bp) in 2.700 CPU sec, 2.770 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 302710, 25, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 293, 640)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1642)
[M::mem_pestat] mean and std.dev: (379.90, 286.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2143)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 411)
[M::mem_pestat] mean and std.dev: (171.15, 71.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 509)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 620, 1805)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5013)
[M::mem_pestat] mean and std.dev: (949.88, 1065.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6617)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 272, 1520)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4224)
[M::mem_pestat] mean and std.dev: (763.41, 952.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5576)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 750322 sequences (100000101 bp) in 2.209 CPU sec, 2.203 real sec...
[M::mem_process_seqs] Processed 754276 reads in 182.215 CPU sec, 5.782 real sec
[M::mem_process_seqs] Processed 751774 reads in 121.428 CPU sec, 3.847 real sec
sorting block 114, #reads = 1111769 mem = 536878170 peak = 1121968128
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 302576, 32, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 390, 1002)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2648)
[M::mem_pestat] mean and std.dev: (525.53, 564.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3471)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 411)
[M::mem_pestat] mean and std.dev: (170.84, 71.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 509)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 513, 2380)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6738)
[M::mem_pestat] mean and std.dev: (1148.32, 1359.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8917)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (323, 758, 1087)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2615)
[M::mem_pestat] mean and std.dev: (777.00, 603.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3379)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 748836 sequences (100000080 bp) in 2.574 CPU sec, 2.647 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 302262, 29, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 186, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 817)
[M::mem_pestat] mean and std.dev: (224.39, 127.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1042)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 159, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 412)
[M::mem_pestat] mean and std.dev: (171.66, 71.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 510)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 700, 1599)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4319)
[M::mem_pestat] mean and std.dev: (934.62, 855.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5679)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 223, 737)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1885)
[M::mem_pestat] mean and std.dev: (323.27, 305.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2459)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 748920 sequences (100000080 bp) in 1.830 CPU sec, 1.830 real sec...
[M::mem_process_seqs] Processed 751656 reads in 176.312 CPU sec, 5.600 real sec
sorting block 115, #reads = 1112885 mem = 536879118 peak = 1121968128
[M::mem_process_seqs] Processed 750322 reads in 118.073 CPU sec, 3.751 real sec
sorting block 116, #reads = 1110263 mem = 536882173 peak = 1155153920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 301384, 24, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 321, 1202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3260)
[M::mem_pestat] mean and std.dev: (665.33, 712.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4289)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 415)
[M::mem_pestat] mean and std.dev: (172.83, 72.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 514)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (71, 307, 1021)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2921)
[M::mem_pestat] mean and std.dev: (554.14, 746.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3871)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 255, 1626)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4594)
[M::mem_pestat] mean and std.dev: (695.41, 904.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6078)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 748894 sequences (100000244 bp) in 2.731 CPU sec, 2.822 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 301387, 19, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 267, 1331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3655)
[M::mem_pestat] mean and std.dev: (609.10, 757.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4817)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 412)
[M::mem_pestat] mean and std.dev: (172.34, 71.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 510)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (60, 213, 2163)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6369)
[M::mem_pestat] mean and std.dev: (728.00, 1170.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8472)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 256, 923)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2441)
[M::mem_pestat] mean and std.dev: (549.63, 592.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3200)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 748580 sequences (100000129 bp) in 2.050 CPU sec, 2.043 real sec...
[M::mem_process_seqs] Processed 748836 reads in 173.731 CPU sec, 5.510 real sec
[M::mem_process_seqs] Processed 748920 reads in 117.215 CPU sec, 3.722 real sec
sorting block 117, #reads = 1110045 mem = 536884178 peak = 1155153920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 301200, 34, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 422, 884)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2356)
[M::mem_pestat] mean and std.dev: (476.62, 391.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3092)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 415)
[M::mem_pestat] mean and std.dev: (172.79, 72.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 514)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (54, 197, 883)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2541)
[M::mem_pestat] mean and std.dev: (400.40, 500.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3370)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 470, 2577)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7361)
[M::mem_pestat] mean and std.dev: (1086.44, 1284.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9753)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 748080 sequences (100000152 bp) in 3.342 CPU sec, 3.490 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 301308, 16, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 273, 1807)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5125)
[M::mem_pestat] mean and std.dev: (1113.21, 1475.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7014)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 415)
[M::mem_pestat] mean and std.dev: (172.63, 71.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 514)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 657, 2397)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6879)
[M::mem_pestat] mean and std.dev: (1181.19, 1410.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9120)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 289, 512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1186)
[M::mem_pestat] mean and std.dev: (320.00, 222.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1523)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 748894 reads in 180.593 CPU sec, 5.730 real sec
[M::process] read 748100 sequences (100000278 bp) in 2.448 CPU sec, 2.483 real sec...
[M::mem_process_seqs] Processed 748580 reads in 125.977 CPU sec, 3.974 real sec
sorting block 118, #reads = 1110968 mem = 536876922 peak = 1155153920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 301267, 21, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 233, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 988)
[M::mem_pestat] mean and std.dev: (292.62, 215.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1262)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 161, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 418)
[M::mem_pestat] mean and std.dev: (173.22, 72.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 518)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 255, 1700)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4832)
[M::mem_pestat] mean and std.dev: (862.90, 1328.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6398)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 319, 795)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2019)
[M::mem_pestat] mean and std.dev: (376.09, 332.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2631)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 748142 sequences (100000186 bp) in 2.888 CPU sec, 3.026 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 301261, 24, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 321, 1343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3669)
[M::mem_pestat] mean and std.dev: (419.60, 407.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4832)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 418)
[M::mem_pestat] mean and std.dev: (173.22, 72.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 518)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (60, 410, 1929)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5667)
[M::mem_pestat] mean and std.dev: (718.55, 883.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7536)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 231, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1015)
[M::mem_pestat] mean and std.dev: (222.83, 96.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1299)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 748080 reads in 185.664 CPU sec, 5.915 real sec
sorting block 119, #reads = 1112772 mem = 536880963 peak = 1155153920
[M::process] read 747856 sequences (100000272 bp) in 2.432 CPU sec, 2.465 real sec...
[M::mem_process_seqs] Processed 748100 reads in 128.718 CPU sec, 4.053 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 301136, 20, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1455)
[M::mem_pestat] mean and std.dev: (298.41, 256.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1895)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 161, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 418)
[M::mem_pestat] mean and std.dev: (173.40, 72.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 518)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (123, 217, 1896)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5442)
[M::mem_pestat] mean and std.dev: (796.16, 1079.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7215)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 527, 907)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2321)
[M::mem_pestat] mean and std.dev: (591.68, 508.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3028)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 120, #reads = 1110213 mem = 536885976 peak = 1155153920
[M::process] read 748534 sequences (100000098 bp) in 3.355 CPU sec, 3.566 real sec...
[M::process] read 22012 sequences (2906860 bp) in 0.320 CPU sec, 0.325 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 301329, 25, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 386, 640)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1462)
[M::mem_pestat] mean and std.dev: (452.39, 301.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1873)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 161, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 418)
[M::mem_pestat] mean and std.dev: (173.76, 72.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 518)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 1070, 1744)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4766)
[M::mem_pestat] mean and std.dev: (957.38, 655.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6277)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 277, 856)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2224)
[M::mem_pestat] mean and std.dev: (467.14, 473.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2908)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 748142 reads in 189.441 CPU sec, 6.076 real sec
[M::mem_process_seqs] Processed 747856 reads in 127.129 CPU sec, 4.069 real sec
sorting block 121, #reads = 1112714 mem = 536876807 peak = 1155153920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 300884, 16, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 416, 997)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2561)
[M::mem_pestat] mean and std.dev: (565.57, 484.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3343)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 415)
[M::mem_pestat] mean and std.dev: (172.75, 72.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 514)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 501, 1363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3629)
[M::mem_pestat] mean and std.dev: (768.44, 846.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4762)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 703, 1511)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4119)
[M::mem_pestat] mean and std.dev: (916.34, 771.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5423)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (1, 8869, 4, 4)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 153, 210)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 400)
[M::mem_pestat] mean and std.dev: (167.20, 69.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 495)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_process_seqs] Processed 748534 reads in 110.014 CPU sec, 3.582 real sec
[M::mem_process_seqs] Processed 22012 reads in 27.734 CPU sec, 0.902 real sec
sorting block 122, #reads = 1110195 mem = 536883298 peak = 1155153920
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000c06f2
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: INTEL(R) XEON(R) PLATINUM 8559C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 136214214
overall: 70933585920 mem 22351.150 user 619.142 sys 760.270 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.659_dm4-T1-TDNA-1_A23MHWWLT4_1.L005\tPU:L005\tSM:659_dm4-T1-TDNA-1_A23MHWWLT4_1\tLB:659_dm4-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 659_dm4-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 659_dm4-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 760.309 sec; CPU: 22970.295 sec
sorting block 123, #reads = 350380 mem = 170354358 peak = 1155153920
uniq header count 1
merging 124 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000c06f2
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: INTEL(R) XEON(R) PLATINUM 8559C
threads: 31 max 192
algo: util-sort
license: sentieon:util=1
output file size: 7262162723
output reads: 137396617
bam_mem_sort: 124 calls 70.207 user 1.976 sys 72.460 real
bam_write: 124 calls 38.064 user 2.492 sys 40.871 real
execute: 1 calls 45.166 user 3.000 sys 812.435 real
merge_files: 1 calls 45.133 user 2.975 sys 51.869 real
parse_chunk: 1974 calls 107.275 user 27.089 sys 136.155 real
read_chunk: 5361 calls 65.268 user 40.609 sys 711.911 real
sort_block: 1 calls 42.940 user 39.961 sys 683.032 real
write_chunk: 3385 calls 44.595 user 2.500 sys 50.483 real
overall: 3681640448 mem 2021.268 user 101.700 sys 812.456 real
ls: cannot access '*.cram': No such file or directory