cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1136_3WJ-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 1768.452 CPU sec, 61.141 real sec
[M::process] read 713824 sequences (100000194 bp) in 1.122 CPU sec, 1.130 real sec...
[M::process] read 710712 sequences (100000247 bp) in 1.787 CPU sec, 1.838 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 283411, 57, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 557, 1121)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2981)
[M::mem_pestat] mean and std.dev: (718.92, 615.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3911)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (141, 204, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 603)
[M::mem_pestat] mean and std.dev: (227.10, 111.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 757)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (107, 306, 1226)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3464)
[M::mem_pestat] mean and std.dev: (611.77, 776.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4583)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 240, 544)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1314)
[M::mem_pestat] mean and std.dev: (329.16, 256.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1699)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 709780 sequences (100000156 bp) in 1.793 CPU sec, 1.802 real sec...
[M::process] read 708844 sequences (100000174 bp) in 1.799 CPU sec, 1.815 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 281583, 42, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 348, 602)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1432)
[M::mem_pestat] mean and std.dev: (376.60, 281.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1847)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 211, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 628)
[M::mem_pestat] mean and std.dev: (234.93, 116.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 789)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (297, 1038, 1242)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3132)
[M::mem_pestat] mean and std.dev: (769.92, 611.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4077)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (272, 626, 1600)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4256)
[M::mem_pestat] mean and std.dev: (932.19, 803.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5584)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 713824 reads in 241.417 CPU sec, 7.681 real sec
[M::mem_process_seqs] Processed 710712 reads in 163.160 CPU sec, 5.261 real sec
sorting block 0, #reads = 1072548 mem = 536890392 peak = 601231360
[M::process] read 707376 sequences (100000244 bp) in 2.573 CPU sec, 2.691 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 282562, 51, 87)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 436, 1929)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5335)
[M::mem_pestat] mean and std.dev: (875.01, 1022.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7038)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 213, 309)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 637)
[M::mem_pestat] mean and std.dev: (236.64, 117.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 801)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (257, 581, 1402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3692)
[M::mem_pestat] mean and std.dev: (740.28, 643.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4837)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (263, 523, 1228)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3158)
[M::mem_pestat] mean and std.dev: (765.43, 678.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4123)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707026 sequences (100000272 bp) in 1.570 CPU sec, 1.572 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 282835, 49, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 380, 1626)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4504)
[M::mem_pestat] mean and std.dev: (763.46, 925.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5943)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 215, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 645)
[M::mem_pestat] mean and std.dev: (239.47, 119.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 811)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (344, 687, 1967)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5213)
[M::mem_pestat] mean and std.dev: (1293.75, 1240.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6836)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 392, 1061)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2759)
[M::mem_pestat] mean and std.dev: (635.43, 567.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3608)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (90, 282061, 28, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 435, 1496)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4054)
[M::mem_pestat] mean and std.dev: (804.86, 842.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5333)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 218, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 658)
[M::mem_pestat] mean and std.dev: (243.05, 121.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 828)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 735, 1278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3292)
[M::mem_pestat] mean and std.dev: (788.56, 617.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4299)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (320, 542, 1268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3164)
[M::mem_pestat] mean and std.dev: (830.30, 730.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4112)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 709780 reads in 305.506 CPU sec, 9.878 real sec
[M::mem_process_seqs] Processed 708844 reads in 243.129 CPU sec, 7.947 real sec
sorting block 1, #reads = 1071518 mem = 536887524 peak = 698748928
[M::mem_process_seqs] Processed 707376 reads in 276.703 CPU sec, 9.065 real sec
[M::process] read 706458 sequences (100000132 bp) in 2.202 CPU sec, 2.394 real sec...
sorting block 2, #reads = 1071033 mem = 536880721 peak = 900444160
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 281512, 56, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 474, 1385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3661)
[M::mem_pestat] mean and std.dev: (652.94, 633.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4799)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 219, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 656)
[M::mem_pestat] mean and std.dev: (242.91, 120.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 825)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 535, 1123)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2939)
[M::mem_pestat] mean and std.dev: (634.84, 599.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3847)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 318, 734)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1750)
[M::mem_pestat] mean and std.dev: (433.13, 370.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2258)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705628 sequences (100000101 bp) in 2.232 CPU sec, 2.609 real sec...
[M::process] read 705742 sequences (100000267 bp) in 1.888 CPU sec, 1.955 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 281209, 34, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 434, 762)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1872)
[M::mem_pestat] mean and std.dev: (455.68, 375.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2427)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 220, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 662)
[M::mem_pestat] mean and std.dev: (244.88, 122.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 833)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 843, 2027)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5569)
[M::mem_pestat] mean and std.dev: (1047.75, 916.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7340)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 401, 666)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1508)
[M::mem_pestat] mean and std.dev: (436.94, 305.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1929)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707026 reads in 220.881 CPU sec, 7.177 real sec
sorting block 3, #reads = 1071462 mem = 536884462 peak = 900444160
[M::mem_process_seqs] Processed 706458 reads in 157.138 CPU sec, 5.194 real sec
[M::process] read 704798 sequences (100000221 bp) in 2.378 CPU sec, 2.538 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 280480, 46, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 338, 945)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2461)
[M::mem_pestat] mean and std.dev: (437.27, 332.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3219)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 222, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 672)
[M::mem_pestat] mean and std.dev: (247.06, 123.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 846)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 676, 1559)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4197)
[M::mem_pestat] mean and std.dev: (1072.98, 1189.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5832)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 270, 702)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1800)
[M::mem_pestat] mean and std.dev: (385.00, 329.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2349)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704140 sequences (100000282 bp) in 2.022 CPU sec, 2.028 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 280916, 48, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 471, 1352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3598)
[M::mem_pestat] mean and std.dev: (716.43, 705.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4721)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 223, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667)
[M::mem_pestat] mean and std.dev: (247.12, 122.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 839)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (438, 578, 1788)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4488)
[M::mem_pestat] mean and std.dev: (1018.68, 925.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5838)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 449, 1259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3319)
[M::mem_pestat] mean and std.dev: (683.93, 620.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4349)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 280913, 51, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 320, 955)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2417)
[M::mem_pestat] mean and std.dev: (446.56, 376.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3148)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 221, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (246.03, 122.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 838)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (377, 663, 1643)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4175)
[M::mem_pestat] mean and std.dev: (876.57, 646.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5441)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 356, 859)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2075)
[M::mem_pestat] mean and std.dev: (481.84, 387.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2683)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705628 reads in 315.955 CPU sec, 10.287 real sec
sorting block 4, #reads = 1071733 mem = 536878485 peak = 900444160
[M::mem_process_seqs] Processed 704798 reads in 257.173 CPU sec, 8.317 real sec
[M::mem_process_seqs] Processed 705742 reads in 287.816 CPU sec, 9.352 real sec
[M::process] read 704402 sequences (100000008 bp) in 2.306 CPU sec, 2.624 real sec...
sorting block 5, #reads = 1067289 mem = 536887728 peak = 900444160
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 280145, 54, 84)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 306, 1110)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3026)
[M::mem_pestat] mean and std.dev: (532.79, 590.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3984)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 223, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 662)
[M::mem_pestat] mean and std.dev: (246.33, 120.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 832)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 469, 1796)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4912)
[M::mem_pestat] mean and std.dev: (953.42, 1059.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6470)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 287, 704)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1718)
[M::mem_pestat] mean and std.dev: (394.12, 296.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2225)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705114 sequences (100000086 bp) in 2.464 CPU sec, 2.618 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (89, 279693, 39, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 336, 904)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2302)
[M::mem_pestat] mean and std.dev: (500.05, 415.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3001)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 222, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653)
[M::mem_pestat] mean and std.dev: (244.66, 118.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 820)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (502, 1186, 3111)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8329)
[M::mem_pestat] mean and std.dev: (1750.36, 1771.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10938)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 430, 821)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1987)
[M::mem_pestat] mean and std.dev: (477.81, 331.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2570)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705032 sequences (100000190 bp) in 1.962 CPU sec, 1.965 real sec...
[M::mem_process_seqs] Processed 704140 reads in 231.513 CPU sec, 7.524 real sec
sorting block 6, #reads = 1067995 mem = 536876331 peak = 901816320
[M::mem_process_seqs] Processed 704402 reads in 160.581 CPU sec, 5.142 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (113, 280167, 42, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 279, 679)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1669)
[M::mem_pestat] mean and std.dev: (413.03, 380.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2164)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 221, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 649)
[M::mem_pestat] mean and std.dev: (243.39, 118.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 815)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 847, 1930)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5374)
[M::mem_pestat] mean and std.dev: (1239.07, 1275.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7096)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 380, 884)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2210)
[M::mem_pestat] mean and std.dev: (527.23, 430.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2873)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704908 sequences (100000039 bp) in 2.555 CPU sec, 2.764 real sec...
sorting block 7, #reads = 1067160 mem = 536882113 peak = 906993664
[M::process] read 704890 sequences (100000219 bp) in 2.139 CPU sec, 2.154 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 280479, 46, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 306, 917)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2423)
[M::mem_pestat] mean and std.dev: (468.95, 442.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3176)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 221, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 652)
[M::mem_pestat] mean and std.dev: (243.43, 118.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 819)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (326, 850, 2199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5945)
[M::mem_pestat] mean and std.dev: (1189.79, 1238.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7818)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 306, 922)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2358)
[M::mem_pestat] mean and std.dev: (540.81, 549.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3076)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705114 reads in 217.828 CPU sec, 6.973 real sec
[M::mem_process_seqs] Processed 705032 reads in 159.392 CPU sec, 5.114 real sec
sorting block 8, #reads = 1067477 mem = 536879963 peak = 906993664
[M::process] read 705722 sequences (100000219 bp) in 2.525 CPU sec, 2.702 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 280660, 48, 94)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 334, 778)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1918)
[M::mem_pestat] mean and std.dev: (405.17, 285.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2488)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 221, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 652)
[M::mem_pestat] mean and std.dev: (244.05, 118.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 819)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 677, 1977)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5525)
[M::mem_pestat] mean and std.dev: (1253.10, 1443.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7299)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 428, 1287)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3391)
[M::mem_pestat] mean and std.dev: (640.78, 640.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4443)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 711588 sequences (100000134 bp) in 2.125 CPU sec, 2.134 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 281033, 49, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 356, 923)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2377)
[M::mem_pestat] mean and std.dev: (582.94, 515.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3104)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 222, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 660)
[M::mem_pestat] mean and std.dev: (244.58, 120.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 830)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (376, 712, 1837)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4759)
[M::mem_pestat] mean and std.dev: (984.96, 732.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6220)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 320, 785)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2001)
[M::mem_pestat] mean and std.dev: (482.34, 407.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2609)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704908 reads in 222.392 CPU sec, 7.127 real sec
sorting block 9, #reads = 1066067 mem = 536881525 peak = 906993664
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 280390, 40, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 277, 699)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1719)
[M::mem_pestat] mean and std.dev: (379.07, 335.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2229)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 223, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 659)
[M::mem_pestat] mean and std.dev: (245.50, 119.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 828)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 613, 1258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3330)
[M::mem_pestat] mean and std.dev: (670.18, 729.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4366)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 320, 628)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1528)
[M::mem_pestat] mean and std.dev: (423.67, 355.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1978)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 709968 sequences (100000012 bp) in 2.347 CPU sec, 2.489 real sec...
[M::mem_process_seqs] Processed 705722 reads in 258.041 CPU sec, 8.238 real sec
[M::mem_process_seqs] Processed 704890 reads in 301.131 CPU sec, 9.664 real sec
sorting block 10, #reads = 1064321 mem = 536881383 peak = 906993664
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (93, 282407, 35, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 302, 782)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1970)
[M::mem_pestat] mean and std.dev: (483.38, 466.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2564)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 209, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 623)
[M::mem_pestat] mean and std.dev: (232.74, 115.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 783)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (480, 800, 2063)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5229)
[M::mem_pestat] mean and std.dev: (1259.50, 1281.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6812)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 313, 727)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1725)
[M::mem_pestat] mean and std.dev: (418.89, 344.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2224)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 709384 sequences (100000000 bp) in 2.573 CPU sec, 2.878 real sec...
[M::process] read 708580 sequences (100000270 bp) in 2.140 CPU sec, 2.149 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 282257, 44, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 383, 733)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1855)
[M::mem_pestat] mean and std.dev: (431.85, 364.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2416)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 212, 308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 634)
[M::mem_pestat] mean and std.dev: (236.11, 116.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 797)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (764, 1648, 2485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5927)
[M::mem_pestat] mean and std.dev: (1529.72, 999.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7648)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 405, 1374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3696)
[M::mem_pestat] mean and std.dev: (553.51, 506.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4857)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 711588 reads in 213.717 CPU sec, 6.818 real sec
[M::mem_process_seqs] Processed 709968 reads in 151.837 CPU sec, 4.860 real sec
sorting block 11, #reads = 1070782 mem = 536883667 peak = 906993664
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 282202, 29, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 333, 928)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2384)
[M::mem_pestat] mean and std.dev: (441.87, 362.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3112)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 214, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 644)
[M::mem_pestat] mean and std.dev: (238.13, 118.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 810)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (337, 698, 1085)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2581)
[M::mem_pestat] mean and std.dev: (715.82, 540.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3329)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 299, 833)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2065)
[M::mem_pestat] mean and std.dev: (391.51, 345.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2681)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707810 sequences (100000173 bp) in 2.861 CPU sec, 3.240 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 282300, 43, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (259, 391, 1221)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3145)
[M::mem_pestat] mean and std.dev: (712.38, 671.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4107)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 216, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 651)
[M::mem_pestat] mean and std.dev: (240.57, 120.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 819)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (289, 715, 764)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1714)
[M::mem_pestat] mean and std.dev: (594.38, 386.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2189)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 343, 1161)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3051)
[M::mem_pestat] mean and std.dev: (638.15, 638.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3996)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706912 sequences (100000029 bp) in 2.197 CPU sec, 2.209 real sec...
[M::mem_process_seqs] Processed 709384 reads in 211.631 CPU sec, 6.782 real sec
sorting block 12, #reads = 1073443 mem = 536884806 peak = 906993664
[M::mem_process_seqs] Processed 708580 reads in 154.099 CPU sec, 4.956 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (87, 282249, 38, 91)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (287, 522, 1371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3539)
[M::mem_pestat] mean and std.dev: (812.61, 831.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4623)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 217, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 658)
[M::mem_pestat] mean and std.dev: (242.46, 120.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 828)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 889, 3300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9560)
[M::mem_pestat] mean and std.dev: (1743.11, 1882.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12690)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 376, 1165)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3043)
[M::mem_pestat] mean and std.dev: (678.62, 565.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3982)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 13, #reads = 1071927 mem = 536889299 peak = 926769152
[M::process] read 706608 sequences (100000128 bp) in 2.697 CPU sec, 2.977 real sec...
[M::process] read 706404 sequences (100000238 bp) in 2.158 CPU sec, 2.173 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 281672, 26, 85)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (281, 497, 1973)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5357)
[M::mem_pestat] mean and std.dev: (1178.54, 1364.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7049)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 219, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 662)
[M::mem_pestat] mean and std.dev: (244.17, 121.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 833)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (721, 1129, 2943)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7387)
[M::mem_pestat] mean and std.dev: (1776.96, 1725.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9609)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 395, 1282)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3424)
[M::mem_pestat] mean and std.dev: (671.33, 647.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4495)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707810 reads in 211.801 CPU sec, 6.802 real sec
[M::mem_process_seqs] Processed 706912 reads in 155.440 CPU sec, 5.032 real sec
sorting block 14, #reads = 1071280 mem = 536880773 peak = 926769152
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 281893, 64, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 328, 494)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1140)
[M::mem_pestat] mean and std.dev: (331.34, 226.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1463)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 220, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (245.48, 122.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 841)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 389, 853)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2271)
[M::mem_pestat] mean and std.dev: (490.81, 424.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2980)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 436, 835)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2017)
[M::mem_pestat] mean and std.dev: (527.16, 416.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2608)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705294 sequences (100000159 bp) in 2.590 CPU sec, 2.775 real sec...
[M::process] read 704788 sequences (100000270 bp) in 2.171 CPU sec, 2.176 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 281460, 56, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 369, 529)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1209)
[M::mem_pestat] mean and std.dev: (380.10, 233.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1549)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 221, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (246.03, 122.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 838)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 666, 1561)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4341)
[M::mem_pestat] mean and std.dev: (737.39, 803.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5731)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (265, 461, 1182)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3016)
[M::mem_pestat] mean and std.dev: (728.61, 664.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3933)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706608 reads in 212.008 CPU sec, 6.790 real sec
[M::mem_process_seqs] Processed 706404 reads in 153.849 CPU sec, 4.918 real sec
sorting block 15, #reads = 1072445 mem = 536882516 peak = 926769152
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 280870, 76, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 302, 822)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2086)
[M::mem_pestat] mean and std.dev: (502.48, 458.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2718)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 223, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 673)
[M::mem_pestat] mean and std.dev: (247.91, 123.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 847)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (344, 792, 1545)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3947)
[M::mem_pestat] mean and std.dev: (697.90, 569.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5148)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 387, 816)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1954)
[M::mem_pestat] mean and std.dev: (509.46, 394.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2523)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704292 sequences (100000190 bp) in 2.689 CPU sec, 2.860 real sec...
[M::process] read 704482 sequences (100000264 bp) in 2.188 CPU sec, 2.191 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 280940, 48, 87)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 343, 655)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1607)
[M::mem_pestat] mean and std.dev: (440.73, 353.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2083)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 223, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (246.42, 121.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 835)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 540, 2051)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5689)
[M::mem_pestat] mean and std.dev: (1055.52, 1124.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7508)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (267, 439, 1052)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2622)
[M::mem_pestat] mean and std.dev: (669.94, 516.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3407)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705294 reads in 211.073 CPU sec, 6.734 real sec
sorting block 16, #reads = 1070179 mem = 536878450 peak = 926769152
[M::mem_process_seqs] Processed 704788 reads in 157.847 CPU sec, 5.056 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 280171, 64, 92)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 513, 1328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3528)
[M::mem_pestat] mean and std.dev: (827.16, 886.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4628)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 662)
[M::mem_pestat] mean and std.dev: (246.53, 120.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 832)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 811, 1813)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4961)
[M::mem_pestat] mean and std.dev: (1167.34, 1236.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6535)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 487, 1575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4235)
[M::mem_pestat] mean and std.dev: (783.34, 676.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5565)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704540 sequences (100000295 bp) in 2.769 CPU sec, 3.173 real sec...
sorting block 17, #reads = 1069516 mem = 536878025 peak = 937361408
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 280482, 35, 95)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 310, 1102)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2882)
[M::mem_pestat] mean and std.dev: (539.42, 559.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3772)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 223, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 656)
[M::mem_pestat] mean and std.dev: (245.28, 119.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 824)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 567, 926)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2414)
[M::mem_pestat] mean and std.dev: (661.37, 572.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3158)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 293, 654)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1590)
[M::mem_pestat] mean and std.dev: (419.14, 377.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2058)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705166 sequences (100000024 bp) in 2.369 CPU sec, 2.411 real sec...
[M::mem_process_seqs] Processed 704292 reads in 216.826 CPU sec, 6.944 real sec
[M::mem_process_seqs] Processed 704482 reads in 157.474 CPU sec, 5.047 real sec
sorting block 18, #reads = 1067375 mem = 536881506 peak = 937361408
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (98, 280405, 46, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 404, 883)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2211)
[M::mem_pestat] mean and std.dev: (553.78, 502.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2875)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 222, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 658)
[M::mem_pestat] mean and std.dev: (245.18, 119.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 827)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 743, 1692)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4598)
[M::mem_pestat] mean and std.dev: (867.02, 805.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6051)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 438, 968)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2458)
[M::mem_pestat] mean and std.dev: (609.22, 525.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3203)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705438 sequences (100000011 bp) in 2.603 CPU sec, 2.903 real sec...
[M::process] read 705360 sequences (100000124 bp) in 2.236 CPU sec, 2.242 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (93, 280613, 59, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 356, 836)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2138)
[M::mem_pestat] mean and std.dev: (508.76, 462.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2789)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 222, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 658)
[M::mem_pestat] mean and std.dev: (244.84, 119.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 827)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (395, 579, 1518)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3764)
[M::mem_pestat] mean and std.dev: (904.63, 857.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4887)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 518, 1294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3494)
[M::mem_pestat] mean and std.dev: (802.79, 843.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4594)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704540 reads in 219.669 CPU sec, 7.290 real sec
[M::mem_process_seqs] Processed 705166 reads in 158.503 CPU sec, 5.072 real sec
sorting block 19, #reads = 1067390 mem = 536876492 peak = 937361408
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 280669, 39, 84)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 396, 1218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3280)
[M::mem_pestat] mean and std.dev: (567.26, 582.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4311)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 221, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 660)
[M::mem_pestat] mean and std.dev: (244.35, 119.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 830)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (309, 769, 1726)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4560)
[M::mem_pestat] mean and std.dev: (1010.43, 930.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5977)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (296, 594, 800)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1808)
[M::mem_pestat] mean and std.dev: (539.87, 302.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2312)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705732 sequences (100000152 bp) in 2.670 CPU sec, 3.087 real sec...
[M::process] read 712650 sequences (100000038 bp) in 2.210 CPU sec, 2.211 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (79, 280267, 52, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 367, 1066)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2742)
[M::mem_pestat] mean and std.dev: (659.64, 687.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3580)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 222, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (245.22, 120.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 831)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (400, 924, 1325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3175)
[M::mem_pestat] mean and std.dev: (961.62, 729.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4100)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (261, 356, 649)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1425)
[M::mem_pestat] mean and std.dev: (462.17, 331.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1813)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705438 reads in 226.152 CPU sec, 7.372 real sec
sorting block 20, #reads = 1068675 mem = 536880343 peak = 937361408
[M::mem_process_seqs] Processed 705360 reads in 162.563 CPU sec, 5.223 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 280252, 39, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 375, 767)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1865)
[M::mem_pestat] mean and std.dev: (457.30, 393.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2414)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 221, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (245.46, 121.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 838)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (306, 902, 2419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6645)
[M::mem_pestat] mean and std.dev: (1269.38, 1360.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8758)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 421, 753)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1801)
[M::mem_pestat] mean and std.dev: (573.07, 466.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2438)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 21, #reads = 1067258 mem = 536883195 peak = 937361408
[M::process] read 712216 sequences (100000218 bp) in 2.755 CPU sec, 3.251 real sec...
[M::process] read 711422 sequences (100000117 bp) in 2.210 CPU sec, 2.217 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 283190, 28, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 366, 1573)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4313)
[M::mem_pestat] mean and std.dev: (821.33, 905.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5683)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 206, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 616)
[M::mem_pestat] mean and std.dev: (230.46, 113.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 774)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (334, 638, 1308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3256)
[M::mem_pestat] mean and std.dev: (948.82, 898.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4543)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 426, 620)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1408)
[M::mem_pestat] mean and std.dev: (371.18, 235.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1802)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705732 reads in 225.457 CPU sec, 7.256 real sec
[M::mem_process_seqs] Processed 712650 reads in 160.419 CPU sec, 5.365 real sec
sorting block 22, #reads = 1066662 mem = 536886306 peak = 937361408
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 282992, 40, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 396, 691)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1649)
[M::mem_pestat] mean and std.dev: (469.44, 324.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2128)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 208, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 620)
[M::mem_pestat] mean and std.dev: (231.57, 114.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 779)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (301, 675, 1380)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3538)
[M::mem_pestat] mean and std.dev: (856.36, 728.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4617)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 425, 1089)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2837)
[M::mem_pestat] mean and std.dev: (699.35, 634.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3711)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 710528 sequences (100000181 bp) in 3.032 CPU sec, 3.280 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 283110, 31, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 563, 1442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3880)
[M::mem_pestat] mean and std.dev: (793.97, 804.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5099)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 210, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 630)
[M::mem_pestat] mean and std.dev: (234.24, 116.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 792)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (272, 554, 1744)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4688)
[M::mem_pestat] mean and std.dev: (983.00, 1240.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6160)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 408, 1112)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2952)
[M::mem_pestat] mean and std.dev: (586.87, 631.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3872)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 709016 sequences (100000221 bp) in 2.245 CPU sec, 2.258 real sec...
[M::mem_process_seqs] Processed 712216 reads in 219.478 CPU sec, 7.264 real sec
[M::mem_process_seqs] Processed 711422 reads in 155.080 CPU sec, 4.968 real sec
sorting block 23, #reads = 1073628 mem = 536883684 peak = 937361408
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 282997, 39, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 352, 511)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1149)
[M::mem_pestat] mean and std.dev: (319.63, 161.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1468)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 211, 308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 634)
[M::mem_pestat] mean and std.dev: (235.68, 117.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 797)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (417, 772, 1123)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2535)
[M::mem_pestat] mean and std.dev: (768.57, 540.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3241)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 514, 1911)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5237)
[M::mem_pestat] mean and std.dev: (865.24, 840.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6900)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708810 sequences (100000100 bp) in 2.659 CPU sec, 3.042 real sec...
[M::process] read 707874 sequences (100000094 bp) in 2.249 CPU sec, 2.262 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 281950, 40, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 399, 1354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3662)
[M::mem_pestat] mean and std.dev: (803.22, 921.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4816)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 214, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 647)
[M::mem_pestat] mean and std.dev: (239.58, 119.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 814)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 777, 1164)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3102)
[M::mem_pestat] mean and std.dev: (843.79, 800.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4071)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 313, 789)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1913)
[M::mem_pestat] mean and std.dev: (485.26, 401.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2475)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 710528 reads in 214.287 CPU sec, 6.882 real sec
sorting block 24, #reads = 1072357 mem = 536878755 peak = 937361408
[M::mem_process_seqs] Processed 709016 reads in 156.252 CPU sec, 5.007 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 282543, 44, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 352, 787)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1949)
[M::mem_pestat] mean and std.dev: (449.14, 362.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2530)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 215, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 651)
[M::mem_pestat] mean and std.dev: (240.17, 119.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 819)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 439, 1252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3458)
[M::mem_pestat] mean and std.dev: (714.10, 764.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4561)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 335, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 928)
[M::mem_pestat] mean and std.dev: (306.47, 127.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1166)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 25, #reads = 1071186 mem = 536879093 peak = 949538816
[M::process] read 707636 sequences (100000018 bp) in 2.566 CPU sec, 3.129 real sec...
[M::process] read 706944 sequences (100000103 bp) in 2.228 CPU sec, 2.232 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 281742, 40, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 266, 953)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2513)
[M::mem_pestat] mean and std.dev: (432.90, 491.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3293)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 217, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 657)
[M::mem_pestat] mean and std.dev: (241.98, 120.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 827)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (449, 1020, 2264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5894)
[M::mem_pestat] mean and std.dev: (1340.45, 1177.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7709)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 380, 1240)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3320)
[M::mem_pestat] mean and std.dev: (674.08, 803.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4360)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 708810 reads in 214.225 CPU sec, 7.135 real sec
[M::mem_process_seqs] Processed 707874 reads in 152.094 CPU sec, 4.876 real sec
sorting block 26, #reads = 1073051 mem = 536880563 peak = 949538816
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 282289, 38, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 357, 1040)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2746)
[M::mem_pestat] mean and std.dev: (639.23, 672.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3599)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 218, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (243.24, 122.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 832)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (313, 545, 1354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3436)
[M::mem_pestat] mean and std.dev: (674.82, 585.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4477)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 390, 2088)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5782)
[M::mem_pestat] mean and std.dev: (921.51, 1088.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7629)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706708 sequences (100000198 bp) in 2.667 CPU sec, 3.053 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 281732, 49, 95)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 330, 1208)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3256)
[M::mem_pestat] mean and std.dev: (659.36, 700.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4280)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 219, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 662)
[M::mem_pestat] mean and std.dev: (244.21, 122.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 833)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (482, 809, 1172)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2552)
[M::mem_pestat] mean and std.dev: (681.50, 427.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3242)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (282, 444, 1285)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3291)
[M::mem_pestat] mean and std.dev: (783.93, 684.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4294)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706988 sequences (100000134 bp) in 2.165 CPU sec, 2.291 real sec...
[M::mem_process_seqs] Processed 707636 reads in 215.731 CPU sec, 7.092 real sec
[M::mem_process_seqs] Processed 706944 reads in 156.501 CPU sec, 5.055 real sec
sorting block 27, #reads = 1071448 mem = 536878359 peak = 949538816
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 281413, 47, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 304, 613)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1515)
[M::mem_pestat] mean and std.dev: (353.49, 250.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1966)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 219, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 656)
[M::mem_pestat] mean and std.dev: (243.04, 120.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 825)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 734, 1416)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3834)
[M::mem_pestat] mean and std.dev: (886.20, 824.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5043)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (275, 734, 1779)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4787)
[M::mem_pestat] mean and std.dev: (1036.81, 973.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6291)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705286 sequences (100000213 bp) in 2.616 CPU sec, 3.078 real sec...
[M::process] read 705116 sequences (100000208 bp) in 2.232 CPU sec, 2.240 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (79, 281639, 55, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 269, 650)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1632)
[M::mem_pestat] mean and std.dev: (352.16, 283.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2123)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 217, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 641)
[M::mem_pestat] mean and std.dev: (240.33, 117.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 805)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (319, 462, 1068)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2566)
[M::mem_pestat] mean and std.dev: (690.87, 642.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3315)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 416, 1105)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2959)
[M::mem_pestat] mean and std.dev: (685.54, 602.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3886)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706708 reads in 215.348 CPU sec, 6.920 real sec
sorting block 28, #reads = 1070610 mem = 536880522 peak = 949538816
[M::mem_process_seqs] Processed 706988 reads in 157.048 CPU sec, 5.030 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (87, 280977, 35, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 329, 1256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3392)
[M::mem_pestat] mean and std.dev: (556.35, 673.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4460)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 222, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (246.24, 122.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 835)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (266, 684, 1718)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4622)
[M::mem_pestat] mean and std.dev: (734.31, 831.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6074)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 411, 705)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1625)
[M::mem_pestat] mean and std.dev: (474.47, 329.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2085)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 29, #reads = 1070357 mem = 536878401 peak = 981078016
[M::process] read 705444 sequences (100000226 bp) in 2.604 CPU sec, 3.056 real sec...
[M::process] read 705274 sequences (100000056 bp) in 2.224 CPU sec, 2.226 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 281018, 28, 93)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 350, 1226)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3362)
[M::mem_pestat] mean and std.dev: (743.67, 847.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4430)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 223, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667)
[M::mem_pestat] mean and std.dev: (246.74, 122.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 839)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (479, 890, 1405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3257)
[M::mem_pestat] mean and std.dev: (914.28, 571.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4183)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (284, 626, 1939)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5249)
[M::mem_pestat] mean and std.dev: (1223.52, 1364.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6904)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705286 reads in 212.537 CPU sec, 6.861 real sec
[M::mem_process_seqs] Processed 705116 reads in 154.767 CPU sec, 4.963 real sec
sorting block 30, #reads = 1069620 mem = 536878579 peak = 981078016
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (81, 281049, 49, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 333, 1162)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3102)
[M::mem_pestat] mean and std.dev: (661.13, 706.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4072)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 222, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 663)
[M::mem_pestat] mean and std.dev: (245.59, 121.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (401, 685, 1855)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4763)
[M::mem_pestat] mean and std.dev: (987.70, 893.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6217)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 395, 997)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2543)
[M::mem_pestat] mean and std.dev: (567.03, 525.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3316)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705860 sequences (100000216 bp) in 2.707 CPU sec, 3.031 real sec...
[M::process] read 706242 sequences (100000001 bp) in 2.210 CPU sec, 2.219 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (108, 280343, 48, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 463, 1562)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4232)
[M::mem_pestat] mean and std.dev: (862.59, 872.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5567)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 222, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (245.72, 121.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 831)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 593, 2402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6900)
[M::mem_pestat] mean and std.dev: (1208.64, 1590.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9149)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (313, 549, 988)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2338)
[M::mem_pestat] mean and std.dev: (669.67, 559.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3013)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705444 reads in 219.843 CPU sec, 7.106 real sec
[M::mem_process_seqs] Processed 705274 reads in 159.699 CPU sec, 5.116 real sec
sorting block 31, #reads = 1068965 mem = 536878530 peak = 981078016
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 280924, 32, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 506, 1393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3695)
[M::mem_pestat] mean and std.dev: (814.55, 811.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4846)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 221, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 657)
[M::mem_pestat] mean and std.dev: (244.52, 120.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 826)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (471, 1352, 2889)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7725)
[M::mem_pestat] mean and std.dev: (1719.53, 1491.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10143)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 389, 1310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3528)
[M::mem_pestat] mean and std.dev: (630.61, 626.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4637)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 712252 sequences (100000001 bp) in 2.642 CPU sec, 3.071 real sec...
[M::process] read 711238 sequences (100000194 bp) in 2.166 CPU sec, 2.170 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 280939, 33, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 356, 1011)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2617)
[M::mem_pestat] mean and std.dev: (547.27, 563.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3420)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 220, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 663)
[M::mem_pestat] mean and std.dev: (245.25, 122.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 663, 1440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3912)
[M::mem_pestat] mean and std.dev: (923.55, 986.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5148)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 394, 1074)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2804)
[M::mem_pestat] mean and std.dev: (586.96, 552.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3669)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705860 reads in 223.095 CPU sec, 7.170 real sec
sorting block 32, #reads = 1066005 mem = 536877797 peak = 981078016
[M::mem_process_seqs] Processed 706242 reads in 164.664 CPU sec, 5.287 real sec
sorting block 33, #reads = 1066485 mem = 536884688 peak = 981078016
[M::process] read 710560 sequences (100000251 bp) in 2.581 CPU sec, 3.060 real sec...
[M::process] read 711110 sequences (100000154 bp) in 2.210 CPU sec, 2.214 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 282852, 50, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 325, 835)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2171)
[M::mem_pestat] mean and std.dev: (450.41, 419.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2839)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 209, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 627)
[M::mem_pestat] mean and std.dev: (233.38, 115.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 788)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 569, 1586)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4346)
[M::mem_pestat] mean and std.dev: (851.32, 806.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5726)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (272, 312, 486)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 914)
[M::mem_pestat] mean and std.dev: (344.84, 173.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1128)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 711238 reads in 119.058 CPU sec, 3.846 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 283176, 36, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 350, 777)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1993)
[M::mem_pestat] mean and std.dev: (476.76, 442.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2601)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 207, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 617)
[M::mem_pestat] mean and std.dev: (231.10, 114.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 775)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (398, 1101, 1550)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3854)
[M::mem_pestat] mean and std.dev: (905.48, 630.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5006)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 377, 740)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1794)
[M::mem_pestat] mean and std.dev: (448.72, 376.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2321)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 282693, 41, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 345, 804)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2026)
[M::mem_pestat] mean and std.dev: (471.72, 413.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2637)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 210, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 628)
[M::mem_pestat] mean and std.dev: (234.55, 116.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 789)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (353, 1303, 2737)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7505)
[M::mem_pestat] mean and std.dev: (1502.83, 1175.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9889)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 415, 1333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3523)
[M::mem_pestat] mean and std.dev: (730.44, 731.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4618)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 710030 sequences (100000180 bp) in 2.235 CPU sec, 2.243 real sec...
[M::mem_process_seqs] Processed 712252 reads in 328.207 CPU sec, 10.612 real sec
sorting block 34, #reads = 1072936 mem = 536880964 peak = 981078016
[M::mem_process_seqs] Processed 710560 reads in 180.617 CPU sec, 6.116 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 283477, 21, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 328, 1068)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2852)
[M::mem_pestat] mean and std.dev: (642.86, 649.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3744)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 210, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 630)
[M::mem_pestat] mean and std.dev: (234.58, 116.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 792)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (116, 770, 1902)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5474)
[M::mem_pestat] mean and std.dev: (1136.33, 1257.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7260)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 297, 658)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1582)
[M::mem_pestat] mean and std.dev: (427.54, 370.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2044)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 709752 sequences (100000158 bp) in 2.721 CPU sec, 3.112 real sec...
sorting block 35, #reads = 1075137 mem = 536880495 peak = 981078016
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (86, 282693, 43, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 257, 778)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1984)
[M::mem_pestat] mean and std.dev: (473.14, 533.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2608)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 212, 309)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 637)
[M::mem_pestat] mean and std.dev: (236.91, 118.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 801)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 413, 2027)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5737)
[M::mem_pestat] mean and std.dev: (858.21, 945.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7592)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (269, 491, 1302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3368)
[M::mem_pestat] mean and std.dev: (745.38, 694.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4401)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708618 sequences (100000012 bp) in 2.221 CPU sec, 2.225 real sec...
[M::mem_process_seqs] Processed 711110 reads in 213.027 CPU sec, 7.130 real sec
[M::mem_process_seqs] Processed 710030 reads in 155.096 CPU sec, 5.020 real sec
sorting block 36, #reads = 1074141 mem = 536878913 peak = 981078016
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (83, 282404, 33, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (261, 404, 1974)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5400)
[M::mem_pestat] mean and std.dev: (947.81, 1259.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7113)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 213, 310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 638)
[M::mem_pestat] mean and std.dev: (237.44, 118.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 802)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (105, 766, 4409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13017)
[M::mem_pestat] mean and std.dev: (2448.15, 2923.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17321)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 404, 591)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1377)
[M::mem_pestat] mean and std.dev: (366.63, 254.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1770)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708192 sequences (100000020 bp) in 2.740 CPU sec, 3.013 real sec...
[M::process] read 707872 sequences (100000220 bp) in 2.209 CPU sec, 2.218 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 282075, 32, 86)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 369, 1231)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3209)
[M::mem_pestat] mean and std.dev: (655.92, 580.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4198)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 215, 314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 648)
[M::mem_pestat] mean and std.dev: (239.83, 119.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 815)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (109, 415, 752)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2038)
[M::mem_pestat] mean and std.dev: (487.03, 501.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2681)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (275, 451, 1541)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4073)
[M::mem_pestat] mean and std.dev: (974.66, 1017.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5339)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 709752 reads in 209.052 CPU sec, 6.728 real sec
[M::mem_process_seqs] Processed 708618 reads in 150.639 CPU sec, 4.856 real sec
sorting block 37, #reads = 1073080 mem = 536876136 peak = 981078016
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 282355, 44, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 371, 885)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2343)
[M::mem_pestat] mean and std.dev: (471.10, 448.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3072)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 216, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 651)
[M::mem_pestat] mean and std.dev: (241.27, 120.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 819)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 307, 1505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4071)
[M::mem_pestat] mean and std.dev: (698.32, 859.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5354)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 340, 786)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1892)
[M::mem_pestat] mean and std.dev: (443.19, 339.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2445)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707304 sequences (100000278 bp) in 2.942 CPU sec, 3.266 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 281598, 35, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 671, 1564)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4284)
[M::mem_pestat] mean and std.dev: (935.56, 931.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5644)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 217, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 660)
[M::mem_pestat] mean and std.dev: (242.36, 121.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 831)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (257, 662, 1768)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4790)
[M::mem_pestat] mean and std.dev: (1105.32, 1124.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6301)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 334, 1014)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2560)
[M::mem_pestat] mean and std.dev: (562.24, 533.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3333)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706874 sequences (100000066 bp) in 2.176 CPU sec, 2.225 real sec...
[M::mem_process_seqs] Processed 708192 reads in 209.402 CPU sec, 6.707 real sec
sorting block 38, #reads = 1072657 mem = 536878099 peak = 981078016
[M::mem_process_seqs] Processed 707872 reads in 152.781 CPU sec, 4.892 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (91, 281467, 51, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 375, 1376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3778)
[M::mem_pestat] mean and std.dev: (712.92, 764.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4979)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 218, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (243.68, 122.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 832)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 494, 856)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2152)
[M::mem_pestat] mean and std.dev: (496.17, 406.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2800)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (261, 375, 1049)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2625)
[M::mem_pestat] mean and std.dev: (729.44, 718.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3602)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 39, #reads = 1070580 mem = 536881598 peak = 981078016
[M::process] read 705894 sequences (100000263 bp) in 2.680 CPU sec, 3.016 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 280925, 56, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (262, 486, 1697)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4567)
[M::mem_pestat] mean and std.dev: (894.03, 784.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6002)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 219, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 656)
[M::mem_pestat] mean and std.dev: (243.44, 120.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 825)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 588, 1655)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4465)
[M::mem_pestat] mean and std.dev: (778.84, 743.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5870)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 356, 847)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2085)
[M::mem_pestat] mean and std.dev: (490.21, 477.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2704)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704844 sequences (100000300 bp) in 2.238 CPU sec, 2.318 real sec...
[M::mem_process_seqs] Processed 707304 reads in 212.464 CPU sec, 6.879 real sec
[M::mem_process_seqs] Processed 706874 reads in 156.745 CPU sec, 5.299 real sec
sorting block 40, #reads = 1070407 mem = 536876650 peak = 981078016
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 281033, 35, 85)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 506, 2789)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7881)
[M::mem_pestat] mean and std.dev: (1456.93, 1647.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10427)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 222, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (246.08, 122.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 838)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (493, 1038, 1963)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4903)
[M::mem_pestat] mean and std.dev: (1316.69, 1161.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6373)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 317, 1678)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4592)
[M::mem_pestat] mean and std.dev: (908.04, 1079.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6049)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704482 sequences (100000207 bp) in 2.705 CPU sec, 2.919 real sec...
[M::process] read 703950 sequences (100000235 bp) in 2.198 CPU sec, 2.197 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (79, 280347, 47, 94)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (266, 406, 950)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2318)
[M::mem_pestat] mean and std.dev: (549.08, 414.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3002)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 224, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 670)
[M::mem_pestat] mean and std.dev: (247.56, 122.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 843)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (54, 477, 1029)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2979)
[M::mem_pestat] mean and std.dev: (587.69, 695.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3954)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 309, 892)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2244)
[M::mem_pestat] mean and std.dev: (458.53, 435.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2920)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705894 reads in 218.011 CPU sec, 7.227 real sec
[M::mem_process_seqs] Processed 704844 reads in 156.774 CPU sec, 5.043 real sec
sorting block 41, #reads = 1069492 mem = 536878485 peak = 981078016
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (86, 280706, 49, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 395, 968)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2526)
[M::mem_pestat] mean and std.dev: (516.91, 486.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3305)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 225, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (248.38, 122.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 844)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (356, 577, 937)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2099)
[M::mem_pestat] mean and std.dev: (645.72, 466.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2680)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 334, 594)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1358)
[M::mem_pestat] mean and std.dev: (320.09, 157.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1740)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704148 sequences (100000066 bp) in 2.711 CPU sec, 3.078 real sec...
[M::process] read 704116 sequences (100000244 bp) in 2.215 CPU sec, 2.263 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (86, 279862, 46, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 336, 1081)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2833)
[M::mem_pestat] mean and std.dev: (642.54, 643.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3709)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (248.25, 122.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 844)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (470, 740, 1435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3365)
[M::mem_pestat] mean and std.dev: (887.90, 690.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4330)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 412, 728)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1678)
[M::mem_pestat] mean and std.dev: (467.18, 331.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2153)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704482 reads in 218.935 CPU sec, 7.057 real sec
sorting block 42, #reads = 1067973 mem = 536881529 peak = 981078016
[M::mem_process_seqs] Processed 703950 reads in 157.672 CPU sec, 5.131 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 280087, 41, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 355, 1029)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2739)
[M::mem_pestat] mean and std.dev: (614.83, 620.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3594)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 662)
[M::mem_pestat] mean and std.dev: (246.73, 120.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 832)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (401, 1115, 1623)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4067)
[M::mem_pestat] mean and std.dev: (1064.23, 722.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5289)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 353, 763)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1899)
[M::mem_pestat] mean and std.dev: (445.06, 343.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2467)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 43, #reads = 1066747 mem = 536876949 peak = 1000144896
[M::process] read 713572 sequences (100000017 bp) in 2.713 CPU sec, 3.187 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (86, 280283, 27, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 547, 1337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3547)
[M::mem_pestat] mean and std.dev: (794.61, 788.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4652)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 224, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (247.72, 121.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 837)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (69, 434, 671)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1875)
[M::mem_pestat] mean and std.dev: (358.04, 324.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2477)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 442, 1238)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3248)
[M::mem_pestat] mean and std.dev: (780.13, 910.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4424)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 714224 sequences (100000247 bp) in 2.438 CPU sec, 2.457 real sec...
[M::mem_process_seqs] Processed 704148 reads in 223.627 CPU sec, 7.294 real sec
[M::mem_process_seqs] Processed 704116 reads in 161.974 CPU sec, 5.185 real sec
sorting block 44, #reads = 1065679 mem = 536877509 peak = 1000144896
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 283329, 54, 88)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 410, 1304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3472)
[M::mem_pestat] mean and std.dev: (670.70, 739.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4556)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (141, 203, 293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 597)
[M::mem_pestat] mean and std.dev: (226.40, 110.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 749)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (430, 877, 1641)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4063)
[M::mem_pestat] mean and std.dev: (958.96, 794.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5274)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 449, 1047)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2729)
[M::mem_pestat] mean and std.dev: (679.84, 603.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3570)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 712420 sequences (100000105 bp) in 2.870 CPU sec, 3.447 real sec...
[M::process] read 710340 sequences (100000117 bp) in 2.251 CPU sec, 2.315 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 283976, 48, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 352, 1111)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2941)
[M::mem_pestat] mean and std.dev: (632.74, 726.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3856)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (140, 201, 291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 593)
[M::mem_pestat] mean and std.dev: (224.85, 110.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 744)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (309, 769, 1389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3549)
[M::mem_pestat] mean and std.dev: (890.44, 818.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4629)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 296, 740)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1836)
[M::mem_pestat] mean and std.dev: (410.88, 396.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2384)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 713572 reads in 244.453 CPU sec, 7.902 real sec
[M::mem_process_seqs] Processed 714224 reads in 173.425 CPU sec, 5.588 real sec
sorting block 45, #reads = 1065684 mem = 536882681 peak = 1000144896
[M::process] read 709166 sequences (100000229 bp) in 2.598 CPU sec, 2.895 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 283746, 28, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 354, 1047)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2689)
[M::mem_pestat] mean and std.dev: (508.09, 431.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3510)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 205, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 607)
[M::mem_pestat] mean and std.dev: (228.98, 113.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 762)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 356, 1242)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3342)
[M::mem_pestat] mean and std.dev: (629.56, 796.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4392)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 329, 823)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2087)
[M::mem_pestat] mean and std.dev: (569.51, 528.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2719)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708800 sequences (100000295 bp) in 2.270 CPU sec, 2.316 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 282854, 30, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 409, 1450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3890)
[M::mem_pestat] mean and std.dev: (828.57, 750.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5110)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 212, 310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 638)
[M::mem_pestat] mean and std.dev: (238.02, 119.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 802)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (347, 689, 952)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2162)
[M::mem_pestat] mean and std.dev: (679.14, 399.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2767)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (283, 430, 1419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3691)
[M::mem_pestat] mean and std.dev: (752.79, 709.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4827)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 712420 reads in 232.687 CPU sec, 7.518 real sec
sorting block 46, #reads = 1069610 mem = 536879657 peak = 1000144896
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 283617, 38, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 289, 801)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2059)
[M::mem_pestat] mean and std.dev: (449.82, 433.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2688)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 209, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 630)
[M::mem_pestat] mean and std.dev: (234.69, 116.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 792)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (389, 922, 1402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3428)
[M::mem_pestat] mean and std.dev: (1017.61, 723.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4441)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 374, 1293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3507)
[M::mem_pestat] mean and std.dev: (661.33, 626.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4614)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708296 sequences (100000265 bp) in 2.446 CPU sec, 2.480 real sec...
[M::mem_process_seqs] Processed 709166 reads in 255.168 CPU sec, 8.170 real sec
[M::mem_process_seqs] Processed 710340 reads in 287.781 CPU sec, 9.266 real sec
sorting block 47, #reads = 1070070 mem = 536878554 peak = 1000144896
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (91, 282399, 39, 91)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 368, 1195)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3139)
[M::mem_pestat] mean and std.dev: (608.62, 662.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4111)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 214, 314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 648)
[M::mem_pestat] mean and std.dev: (240.29, 120.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 815)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (375, 606, 1109)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2577)
[M::mem_pestat] mean and std.dev: (603.65, 431.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3311)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 380, 982)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2500)
[M::mem_pestat] mean and std.dev: (525.96, 455.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3259)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708124 sequences (100000299 bp) in 2.653 CPU sec, 3.368 real sec...
[M::process] read 706766 sequences (100000157 bp) in 2.221 CPU sec, 2.232 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (83, 282196, 44, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 466, 1367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3659)
[M::mem_pestat] mean and std.dev: (751.93, 794.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4805)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 215, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 654)
[M::mem_pestat] mean and std.dev: (241.88, 122.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 823)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (350, 887, 1792)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4676)
[M::mem_pestat] mean and std.dev: (1215.44, 1146.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6118)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 548, 1468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3928)
[M::mem_pestat] mean and std.dev: (919.89, 913.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5158)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 708800 reads in 226.552 CPU sec, 7.428 real sec
sorting block 48, #reads = 1070983 mem = 536878629 peak = 1000144896
[M::process] read 705840 sequences (100000209 bp) in 2.344 CPU sec, 2.496 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 281780, 37, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 442, 1193)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3217)
[M::mem_pestat] mean and std.dev: (794.82, 838.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4229)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 214, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 645)
[M::mem_pestat] mean and std.dev: (240.23, 120.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 811)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 621, 2170)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6154)
[M::mem_pestat] mean and std.dev: (1070.32, 1411.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8146)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 374, 1695)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4705)
[M::mem_pestat] mean and std.dev: (910.58, 1022.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6210)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 708124 reads in 133.969 CPU sec, 4.405 real sec
sorting block 49, #reads = 1068204 mem = 536879383 peak = 1000144896
[M::mem_process_seqs] Processed 708296 reads in 344.757 CPU sec, 11.237 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 280309, 55, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 483, 1101)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2849)
[M::mem_pestat] mean and std.dev: (658.41, 562.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3723)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 217, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653)
[M::mem_pestat] mean and std.dev: (242.75, 120.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 821)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (411, 1025, 1499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3675)
[M::mem_pestat] mean and std.dev: (936.71, 643.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4763)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 431, 944)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2364)
[M::mem_pestat] mean and std.dev: (614.42, 512.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3074)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705332 sequences (100000052 bp) in 2.748 CPU sec, 3.415 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (95, 280334, 46, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 317, 680)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1646)
[M::mem_pestat] mean and std.dev: (389.38, 292.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2129)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 219, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 657)
[M::mem_pestat] mean and std.dev: (244.52, 121.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 826)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (370, 672, 2138)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5674)
[M::mem_pestat] mean and std.dev: (875.49, 836.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7442)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 333, 1146)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3024)
[M::mem_pestat] mean and std.dev: (563.21, 518.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3963)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705726 sequences (100000110 bp) in 2.255 CPU sec, 2.264 real sec...
[M::mem_process_seqs] Processed 706766 reads in 273.710 CPU sec, 8.868 real sec
sorting block 50, #reads = 1067844 mem = 536892832 peak = 1000144896
[M::mem_process_seqs] Processed 705840 reads in 180.667 CPU sec, 5.832 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 280545, 40, 100)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 269, 631)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1599)
[M::mem_pestat] mean and std.dev: (373.26, 322.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2083)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 220, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 657)
[M::mem_pestat] mean and std.dev: (244.44, 120.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 826)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (423, 671, 1736)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4362)
[M::mem_pestat] mean and std.dev: (953.64, 828.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5675)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (290, 754, 1645)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4355)
[M::mem_pestat] mean and std.dev: (906.35, 866.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5710)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 51, #reads = 1063112 mem = 536878456 peak = 1000144896
[M::process] read 706384 sequences (100000164 bp) in 2.895 CPU sec, 3.216 real sec...
[M::process] read 706000 sequences (100000134 bp) in 2.340 CPU sec, 2.372 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (87, 280895, 54, 93)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (273, 351, 960)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2334)
[M::mem_pestat] mean and std.dev: (442.07, 384.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3021)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 219, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 651)
[M::mem_pestat] mean and std.dev: (243.34, 120.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 818)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (262, 618, 1079)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2713)
[M::mem_pestat] mean and std.dev: (667.43, 539.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3530)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (272, 478, 1207)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3077)
[M::mem_pestat] mean and std.dev: (678.54, 649.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4012)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705332 reads in 233.762 CPU sec, 7.509 real sec
[M::mem_process_seqs] Processed 705726 reads in 170.871 CPU sec, 5.499 real sec
sorting block 52, #reads = 1064511 mem = 536887627 peak = 1000144896
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 281041, 37, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 360, 756)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1806)
[M::mem_pestat] mean and std.dev: (456.83, 374.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2331)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 217, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 647)
[M::mem_pestat] mean and std.dev: (241.50, 119.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 813)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (330, 709, 2199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5937)
[M::mem_pestat] mean and std.dev: (948.45, 813.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7806)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 352, 788)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1956)
[M::mem_pestat] mean and std.dev: (450.90, 346.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2540)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705614 sequences (100000074 bp) in 2.730 CPU sec, 2.937 real sec...
[M::process] read 711228 sequences (100000041 bp) in 2.362 CPU sec, 2.365 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 281138, 61, 89)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 247, 693)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1775)
[M::mem_pestat] mean and std.dev: (428.21, 384.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2316)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 219, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 654)
[M::mem_pestat] mean and std.dev: (243.63, 120.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 822)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 629, 2277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6511)
[M::mem_pestat] mean and std.dev: (1115.68, 1251.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8628)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (261, 452, 832)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1974)
[M::mem_pestat] mean and std.dev: (522.71, 328.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2545)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706384 reads in 233.250 CPU sec, 7.478 real sec
sorting block 53, #reads = 1064435 mem = 536879692 peak = 1000144896
[M::mem_process_seqs] Processed 706000 reads in 176.362 CPU sec, 5.654 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 280661, 51, 96)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 336, 1363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3701)
[M::mem_pestat] mean and std.dev: (691.70, 725.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4870)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 219, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 654)
[M::mem_pestat] mean and std.dev: (243.68, 120.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 822)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 790, 1809)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4967)
[M::mem_pestat] mean and std.dev: (961.08, 876.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6546)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 309, 793)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1993)
[M::mem_pestat] mean and std.dev: (419.12, 315.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2593)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717272 sequences (100000040 bp) in 2.826 CPU sec, 3.029 real sec...
[M::process] read 715858 sequences (100000224 bp) in 2.371 CPU sec, 2.393 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (85, 281965, 62, 96)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 405, 863)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2219)
[M::mem_pestat] mean and std.dev: (507.08, 421.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2897)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 208, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 618)
[M::mem_pestat] mean and std.dev: (232.63, 115.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 776)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (397, 832, 1360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3286)
[M::mem_pestat] mean and std.dev: (995.32, 816.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4261)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (258, 516, 1437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3795)
[M::mem_pestat] mean and std.dev: (776.03, 869.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4974)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705614 reads in 247.768 CPU sec, 7.934 real sec
sorting block 54, #reads = 1064700 mem = 536878301 peak = 1000144896
[M::mem_process_seqs] Processed 711228 reads in 193.629 CPU sec, 6.237 real sec
sorting block 55, #reads = 1061556 mem = 536879439 peak = 1041039360
[M::process] read 713920 sequences (100000145 bp) in 2.865 CPU sec, 3.130 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 285067, 37, 81)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 457, 1016)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2618)
[M::mem_pestat] mean and std.dev: (572.75, 513.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3419)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 197, 284)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 576)
[M::mem_pestat] mean and std.dev: (219.73, 106.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 722)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 479, 1145)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2995)
[M::mem_pestat] mean and std.dev: (721.51, 723.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3920)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 318, 870)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2244)
[M::mem_pestat] mean and std.dev: (483.43, 422.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2931)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 712540 sequences (100000198 bp) in 2.323 CPU sec, 2.328 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 284542, 48, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 539, 1335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3555)
[M::mem_pestat] mean and std.dev: (871.02, 932.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4665)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (141, 203, 294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 600)
[M::mem_pestat] mean and std.dev: (226.86, 111.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 753)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (344, 725, 1045)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2447)
[M::mem_pestat] mean and std.dev: (730.56, 562.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3148)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 393, 1220)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3268)
[M::mem_pestat] mean and std.dev: (682.64, 721.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4292)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 284825, 35, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 337, 714)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1826)
[M::mem_pestat] mean and std.dev: (434.17, 389.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2382)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 200, 289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 589)
[M::mem_pestat] mean and std.dev: (223.04, 109.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 739)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (417, 883, 1647)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4107)
[M::mem_pestat] mean and std.dev: (1025.67, 851.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5337)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 324, 948)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2418)
[M::mem_pestat] mean and std.dev: (504.11, 447.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3153)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 717272 reads in 368.880 CPU sec, 11.910 real sec
[M::mem_process_seqs] Processed 713920 reads in 294.165 CPU sec, 9.572 real sec
[M::mem_process_seqs] Processed 715858 reads in 334.191 CPU sec, 10.899 real sec
sorting block 56, #reads = 1063904 mem = 536879082 peak = 1041039360
[M::process] read 710216 sequences (100000057 bp) in 2.904 CPU sec, 3.039 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 283389, 30, 89)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 252, 834)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2182)
[M::mem_pestat] mean and std.dev: (455.02, 479.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2856)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 206, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 613)
[M::mem_pestat] mean and std.dev: (230.63, 114.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 770)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 480, 1383)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3849)
[M::mem_pestat] mean and std.dev: (721.33, 796.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5082)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 279, 740)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1882)
[M::mem_pestat] mean and std.dev: (475.71, 437.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2453)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 57, #reads = 1063596 mem = 536880651 peak = 1042698240
[M::process] read 709778 sequences (100000073 bp) in 2.557 CPU sec, 3.226 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 282621, 35, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 351, 816)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1984)
[M::mem_pestat] mean and std.dev: (453.30, 409.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2568)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 210, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 628)
[M::mem_pestat] mean and std.dev: (234.80, 116.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 789)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (347, 835, 2340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6326)
[M::mem_pestat] mean and std.dev: (1198.53, 1321.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8319)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 322, 904)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2294)
[M::mem_pestat] mean and std.dev: (564.19, 574.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2989)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 709184 sequences (100000122 bp) in 2.251 CPU sec, 2.261 real sec...
[M::mem_process_seqs] Processed 712540 reads in 251.879 CPU sec, 8.199 real sec
[M::mem_process_seqs] Processed 710216 reads in 179.775 CPU sec, 5.847 real sec
sorting block 58, #reads = 1064677 mem = 536877561 peak = 1042698240
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 282796, 35, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 587, 917)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2369)
[M::mem_pestat] mean and std.dev: (570.13, 501.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3095)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 211, 308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 634)
[M::mem_pestat] mean and std.dev: (236.47, 117.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 797)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 908, 1444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3854)
[M::mem_pestat] mean and std.dev: (904.00, 743.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5059)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 363, 720)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1722)
[M::mem_pestat] mean and std.dev: (393.26, 283.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2223)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708014 sequences (100000096 bp) in 2.681 CPU sec, 3.058 real sec...
[M::process] read 707566 sequences (100000172 bp) in 2.333 CPU sec, 2.507 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 282440, 50, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 309, 629)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1509)
[M::mem_pestat] mean and std.dev: (432.10, 369.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1949)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 212, 309)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 635)
[M::mem_pestat] mean and std.dev: (237.47, 118.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 798)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (285, 665, 3522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9996)
[M::mem_pestat] mean and std.dev: (2069.46, 2789.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13233)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 292, 724)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1734)
[M::mem_pestat] mean and std.dev: (471.29, 429.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2239)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 709778 reads in 238.103 CPU sec, 7.679 real sec
[M::mem_process_seqs] Processed 709184 reads in 170.029 CPU sec, 5.473 real sec
sorting block 59, #reads = 1065170 mem = 536883476 peak = 1042698240
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 282106, 41, 84)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 362, 915)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2311)
[M::mem_pestat] mean and std.dev: (565.10, 539.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3009)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 215, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 642)
[M::mem_pestat] mean and std.dev: (239.53, 119.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 807)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (288, 520, 1477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3855)
[M::mem_pestat] mean and std.dev: (747.92, 737.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5044)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (279, 596, 1986)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5400)
[M::mem_pestat] mean and std.dev: (936.36, 876.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7107)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706118 sequences (100000222 bp) in 2.965 CPU sec, 3.334 real sec...
[M::process] read 706124 sequences (100000053 bp) in 2.216 CPU sec, 2.219 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 281475, 40, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 283, 710)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1762)
[M::mem_pestat] mean and std.dev: (425.05, 408.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2288)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 216, 314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 646)
[M::mem_pestat] mean and std.dev: (241.12, 119.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 812)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (319, 713, 1316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3310)
[M::mem_pestat] mean and std.dev: (780.60, 817.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4307)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 391, 1056)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2666)
[M::mem_pestat] mean and std.dev: (658.65, 670.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3471)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 708014 reads in 237.570 CPU sec, 7.635 real sec
sorting block 60, #reads = 1067341 mem = 536876954 peak = 1045495808
[M::mem_process_seqs] Processed 707566 reads in 171.954 CPU sec, 5.520 real sec
sorting block 61, #reads = 1065083 mem = 536877692 peak = 1049612288
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 280484, 51, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 388, 894)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2310)
[M::mem_pestat] mean and std.dev: (558.55, 550.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3018)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 218, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 650)
[M::mem_pestat] mean and std.dev: (242.82, 120.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 817)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (259, 733, 1317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3433)
[M::mem_pestat] mean and std.dev: (887.69, 773.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4491)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 410, 1587)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4259)
[M::mem_pestat] mean and std.dev: (890.44, 939.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5595)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706284 sequences (100000064 bp) in 2.640 CPU sec, 3.096 real sec...
[M::process] read 706524 sequences (100000155 bp) in 2.359 CPU sec, 2.450 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (83, 280767, 54, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 336, 991)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2535)
[M::mem_pestat] mean and std.dev: (485.77, 392.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3307)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 218, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653)
[M::mem_pestat] mean and std.dev: (243.24, 121.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 821)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (69, 504, 834)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2364)
[M::mem_pestat] mean and std.dev: (444.96, 402.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3129)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 326, 798)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2060)
[M::mem_pestat] mean and std.dev: (387.76, 367.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2691)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706118 reads in 234.709 CPU sec, 7.619 real sec
[M::mem_process_seqs] Processed 706124 reads in 169.893 CPU sec, 5.513 real sec
sorting block 62, #reads = 1064675 mem = 536876976 peak = 1049612288
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 280562, 42, 84)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 404, 1070)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2798)
[M::mem_pestat] mean and std.dev: (560.75, 509.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3662)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 218, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 651)
[M::mem_pestat] mean and std.dev: (243.29, 121.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 818)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (286, 801, 1614)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4270)
[M::mem_pestat] mean and std.dev: (988.49, 899.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5598)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 378, 922)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2270)
[M::mem_pestat] mean and std.dev: (559.68, 486.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2944)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706628 sequences (100000070 bp) in 3.006 CPU sec, 3.323 real sec...
[M::process] read 715746 sequences (100000243 bp) in 2.139 CPU sec, 2.181 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 281252, 39, 91)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 268, 1203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3323)
[M::mem_pestat] mean and std.dev: (697.77, 792.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4383)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 218, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653)
[M::mem_pestat] mean and std.dev: (242.94, 121.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 821)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (350, 656, 1657)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4271)
[M::mem_pestat] mean and std.dev: (828.08, 736.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5578)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (260, 422, 1178)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3014)
[M::mem_pestat] mean and std.dev: (721.16, 712.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3932)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706284 reads in 237.198 CPU sec, 7.650 real sec
[M::mem_process_seqs] Processed 706524 reads in 173.430 CPU sec, 5.623 real sec
sorting block 63, #reads = 1065215 mem = 536883514 peak = 1049612288
[M::process] read 714216 sequences (100000030 bp) in 2.726 CPU sec, 3.102 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 280401, 38, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 323, 509)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1169)
[M::mem_pestat] mean and std.dev: (330.81, 241.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1499)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 216, 314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 646)
[M::mem_pestat] mean and std.dev: (241.34, 120.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 812)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 549, 1493)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4025)
[M::mem_pestat] mean and std.dev: (909.38, 955.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5291)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 396, 875)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2153)
[M::mem_pestat] mean and std.dev: (531.53, 475.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2792)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 712414 sequences (100000214 bp) in 2.267 CPU sec, 2.273 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 284135, 47, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 315, 943)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2471)
[M::mem_pestat] mean and std.dev: (492.09, 451.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3235)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 200, 289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 589)
[M::mem_pestat] mean and std.dev: (223.11, 109.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 739)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (398, 736, 2568)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6908)
[M::mem_pestat] mean and std.dev: (1379.24, 1543.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9078)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 665, 1694)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4680)
[M::mem_pestat] mean and std.dev: (883.68, 986.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6173)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 284567, 44, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 385, 1138)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3088)
[M::mem_pestat] mean and std.dev: (620.92, 531.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4063)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (140, 202, 291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 593)
[M::mem_pestat] mean and std.dev: (224.99, 110.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 744)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (431, 842, 1499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3635)
[M::mem_pestat] mean and std.dev: (933.48, 722.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4703)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 333, 515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1115)
[M::mem_pestat] mean and std.dev: (340.51, 222.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1415)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706628 reads in 357.287 CPU sec, 11.535 real sec
sorting block 64, #reads = 1064459 mem = 536878928 peak = 1049612288
[M::mem_process_seqs] Processed 715746 reads in 277.414 CPU sec, 8.950 real sec
[M::mem_process_seqs] Processed 714216 reads in 312.556 CPU sec, 10.170 real sec
sorting block 65, #reads = 1058897 mem = 536878315 peak = 1049612288
[M::process] read 711348 sequences (100000063 bp) in 2.850 CPU sec, 3.165 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 283493, 33, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 465, 1051)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2689)
[M::mem_pestat] mean and std.dev: (516.20, 448.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3508)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 206, 298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 610)
[M::mem_pestat] mean and std.dev: (229.68, 113.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 766)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 635, 1471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3925)
[M::mem_pestat] mean and std.dev: (891.52, 864.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5152)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (260, 600, 1729)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4667)
[M::mem_pestat] mean and std.dev: (970.75, 942.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6136)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 709474 sequences (100000134 bp) in 2.595 CPU sec, 2.998 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 283428, 42, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 605, 1769)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4913)
[M::mem_pestat] mean and std.dev: (895.03, 876.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6485)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 208, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 618)
[M::mem_pestat] mean and std.dev: (232.43, 115.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 776)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 890, 1477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4023)
[M::mem_pestat] mean and std.dev: (876.36, 747.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5296)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 396, 983)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2545)
[M::mem_pestat] mean and std.dev: (533.89, 444.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3326)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 712414 reads in 228.168 CPU sec, 7.409 real sec
sorting block 66, #reads = 1070336 mem = 536878365 peak = 1049612288
[M::process] read 709066 sequences (100000274 bp) in 2.445 CPU sec, 2.465 real sec...
[M::mem_process_seqs] Processed 711348 reads in 163.682 CPU sec, 5.269 real sec
sorting block 67, #reads = 1071509 mem = 536877435 peak = 1071050752
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 283155, 55, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 337, 809)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1945)
[M::mem_pestat] mean and std.dev: (411.37, 330.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2513)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 212, 308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 632)
[M::mem_pestat] mean and std.dev: (236.31, 116.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 794)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (286, 707, 2055)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5593)
[M::mem_pestat] mean and std.dev: (1205.70, 1088.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7362)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (275, 520, 1246)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3188)
[M::mem_pestat] mean and std.dev: (648.09, 550.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4159)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708660 sequences (100000108 bp) in 2.837 CPU sec, 3.392 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 283094, 47, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 306, 761)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1883)
[M::mem_pestat] mean and std.dev: (420.83, 394.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2444)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 213, 309)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 635)
[M::mem_pestat] mean and std.dev: (237.22, 117.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 798)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (253, 665, 1564)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4186)
[M::mem_pestat] mean and std.dev: (755.88, 643.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5497)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 546, 2045)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5623)
[M::mem_pestat] mean and std.dev: (996.05, 1091.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7412)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708270 sequences (100000181 bp) in 2.219 CPU sec, 2.292 real sec...
[M::mem_process_seqs] Processed 709474 reads in 218.608 CPU sec, 7.051 real sec
[M::mem_process_seqs] Processed 709066 reads in 156.019 CPU sec, 5.016 real sec
sorting block 68, #reads = 1071669 mem = 536885294 peak = 1071050752
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 283226, 33, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 426, 904)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2318)
[M::mem_pestat] mean and std.dev: (575.81, 545.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3025)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 214, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 642)
[M::mem_pestat] mean and std.dev: (239.09, 118.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 807)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (376, 749, 2005)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5263)
[M::mem_pestat] mean and std.dev: (1037.97, 730.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6892)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 418, 1106)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2836)
[M::mem_pestat] mean and std.dev: (662.71, 609.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3701)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708928 sequences (100000062 bp) in 2.943 CPU sec, 3.411 real sec...
[M::process] read 709178 sequences (100000116 bp) in 2.311 CPU sec, 2.314 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 282179, 39, 81)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (301, 496, 1125)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2773)
[M::mem_pestat] mean and std.dev: (639.39, 538.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3597)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 214, 310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 636)
[M::mem_pestat] mean and std.dev: (237.99, 117.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 799)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (40, 626, 1375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4045)
[M::mem_pestat] mean and std.dev: (726.59, 800.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5380)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 283, 621)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1483)
[M::mem_pestat] mean and std.dev: (389.58, 277.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1914)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 708660 reads in 225.441 CPU sec, 7.269 real sec
[M::mem_process_seqs] Processed 708270 reads in 162.581 CPU sec, 5.300 real sec
sorting block 69, #reads = 1072136 mem = 536878001 peak = 1071050752
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 282463, 48, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 543, 1149)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3111)
[M::mem_pestat] mean and std.dev: (637.89, 599.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4092)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 212, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 626)
[M::mem_pestat] mean and std.dev: (235.73, 115.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 786)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (425, 887, 1981)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5093)
[M::mem_pestat] mean and std.dev: (1313.26, 1363.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6766)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 412, 1066)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2808)
[M::mem_pestat] mean and std.dev: (526.44, 441.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3679)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708662 sequences (100000034 bp) in 2.716 CPU sec, 3.086 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 282515, 38, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 466, 646)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1526)
[M::mem_pestat] mean and std.dev: (413.08, 290.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1966)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 211, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 626)
[M::mem_pestat] mean and std.dev: (235.04, 115.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 786)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 582, 969)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2593)
[M::mem_pestat] mean and std.dev: (596.61, 605.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3405)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 363, 1171)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3001)
[M::mem_pestat] mean and std.dev: (703.42, 725.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3916)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707598 sequences (100000056 bp) in 2.222 CPU sec, 2.251 real sec...
[M::mem_process_seqs] Processed 708928 reads in 227.007 CPU sec, 7.361 real sec
sorting block 70, #reads = 1070071 mem = 536879323 peak = 1071050752
[M::mem_process_seqs] Processed 709178 reads in 164.286 CPU sec, 5.321 real sec
sorting block 71, #reads = 1070272 mem = 536884007 peak = 1071050752
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 282140, 46, 90)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 360, 822)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2140)
[M::mem_pestat] mean and std.dev: (532.05, 477.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2799)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 213, 308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 632)
[M::mem_pestat] mean and std.dev: (237.14, 117.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 794)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (277, 1104, 1511)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3979)
[M::mem_pestat] mean and std.dev: (954.57, 719.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5213)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 495, 860)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2120)
[M::mem_pestat] mean and std.dev: (541.61, 425.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2750)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706630 sequences (100000096 bp) in 3.075 CPU sec, 3.252 real sec...
[M::process] read 707026 sequences (100000130 bp) in 2.331 CPU sec, 2.362 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 281741, 44, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (258, 444, 1879)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5121)
[M::mem_pestat] mean and std.dev: (857.52, 1013.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6742)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 215, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 643)
[M::mem_pestat] mean and std.dev: (240.27, 119.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 808)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (126, 616, 1258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3522)
[M::mem_pestat] mean and std.dev: (572.18, 545.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4654)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 449, 907)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2237)
[M::mem_pestat] mean and std.dev: (549.31, 380.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2902)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 708662 reads in 229.641 CPU sec, 7.442 real sec
[M::mem_process_seqs] Processed 707598 reads in 166.096 CPU sec, 5.365 real sec
sorting block 72, #reads = 1068977 mem = 536879315 peak = 1071050752
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 281134, 65, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 435, 1205)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3225)
[M::mem_pestat] mean and std.dev: (798.58, 811.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4235)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 217, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 650)
[M::mem_pestat] mean and std.dev: (242.09, 120.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 817)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (289, 747, 1606)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4240)
[M::mem_pestat] mean and std.dev: (799.03, 713.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5557)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 644, 1436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3828)
[M::mem_pestat] mean and std.dev: (833.06, 810.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5024)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707246 sequences (100000198 bp) in 2.820 CPU sec, 3.282 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 280780, 41, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 435, 1203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3201)
[M::mem_pestat] mean and std.dev: (647.74, 698.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4200)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 216, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 640)
[M::mem_pestat] mean and std.dev: (240.08, 118.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 804)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (331, 869, 1336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3346)
[M::mem_pestat] mean and std.dev: (719.72, 655.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4351)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 380, 1050)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2750)
[M::mem_pestat] mean and std.dev: (594.79, 599.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3600)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718488 sequences (100000217 bp) in 2.473 CPU sec, 2.695 real sec...
[M::mem_process_seqs] Processed 706630 reads in 232.476 CPU sec, 7.525 real sec
sorting block 73, #reads = 1067004 mem = 536879078 peak = 1071050752
[M::mem_process_seqs] Processed 707026 reads in 169.663 CPU sec, 5.492 real sec
[M::process] read 718182 sequences (100000260 bp) in 2.969 CPU sec, 3.416 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 280939, 42, 91)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 357, 776)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1916)
[M::mem_pestat] mean and std.dev: (456.71, 375.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2486)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 215, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 643)
[M::mem_pestat] mean and std.dev: (239.97, 119.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 808)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (304, 681, 1950)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5242)
[M::mem_pestat] mean and std.dev: (1128.92, 1213.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6888)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 382, 1363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3589)
[M::mem_pestat] mean and std.dev: (807.81, 793.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4702)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 716338 sequences (100000236 bp) in 2.387 CPU sec, 2.392 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 284776, 44, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 227, 631)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1557)
[M::mem_pestat] mean and std.dev: (342.26, 306.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2020)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 195, 280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 566)
[M::mem_pestat] mean and std.dev: (217.06, 105.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 709)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 671, 1128)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2948)
[M::mem_pestat] mean and std.dev: (633.00, 530.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3858)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 457, 855)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2155)
[M::mem_pestat] mean and std.dev: (511.14, 395.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2805)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707246 reads in 266.532 CPU sec, 8.646 real sec
sorting block 74, #reads = 1065617 mem = 536879349 peak = 1071050752
[M::mem_process_seqs] Processed 718488 reads in 192.260 CPU sec, 6.257 real sec
sorting block 75, #reads = 1057250 mem = 536883564 peak = 1071050752
[M::process] read 715690 sequences (100000180 bp) in 3.070 CPU sec, 3.327 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 285695, 36, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 401, 946)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2458)
[M::mem_pestat] mean and std.dev: (610.96, 544.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3214)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 196, 281)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 569)
[M::mem_pestat] mean and std.dev: (217.87, 105.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 713)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 527, 1254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3406)
[M::mem_pestat] mean and std.dev: (680.06, 731.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4482)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 279, 1538)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4276)
[M::mem_pestat] mean and std.dev: (788.45, 963.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5645)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 712672 sequences (100000233 bp) in 2.325 CPU sec, 2.413 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 284834, 45, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 393, 1375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3741)
[M::mem_pestat] mean and std.dev: (679.51, 777.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4924)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 198, 286)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 580)
[M::mem_pestat] mean and std.dev: (220.97, 107.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 727)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 913, 2471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7009)
[M::mem_pestat] mean and std.dev: (1433.36, 1574.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9278)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (274, 587, 975)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2377)
[M::mem_pestat] mean and std.dev: (718.43, 590.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3082)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 284440, 32, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 397, 1421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3851)
[M::mem_pestat] mean and std.dev: (672.63, 682.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5066)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 200, 290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 592)
[M::mem_pestat] mean and std.dev: (223.71, 109.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 743)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (322, 751, 1626)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4234)
[M::mem_pestat] mean and std.dev: (794.07, 656.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5538)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 254, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1044)
[M::mem_pestat] mean and std.dev: (275.95, 157.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1337)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 718182 reads in 372.659 CPU sec, 12.017 real sec
[M::mem_process_seqs] Processed 716338 reads in 297.074 CPU sec, 9.668 real sec
sorting block 76, #reads = 1064865 mem = 536875313 peak = 1071050752
[M::mem_process_seqs] Processed 715690 reads in 337.333 CPU sec, 11.030 real sec
[M::process] read 711492 sequences (100000004 bp) in 3.061 CPU sec, 3.364 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 283737, 40, 81)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 335, 916)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2342)
[M::mem_pestat] mean and std.dev: (450.46, 386.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3055)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 206, 298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 610)
[M::mem_pestat] mean and std.dev: (229.63, 113.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 766)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (403, 791, 1126)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2572)
[M::mem_pestat] mean and std.dev: (628.57, 357.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3295)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 343, 1511)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4179)
[M::mem_pestat] mean and std.dev: (889.95, 1156.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5517)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 77, #reads = 1062501 mem = 536880372 peak = 1071050752
[M::process] read 711026 sequences (100000117 bp) in 2.721 CPU sec, 2.993 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 283853, 52, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 307, 755)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1891)
[M::mem_pestat] mean and std.dev: (485.69, 436.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2459)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 207, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 617)
[M::mem_pestat] mean and std.dev: (231.97, 114.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 775)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (318, 669, 2152)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5820)
[M::mem_pestat] mean and std.dev: (1049.91, 1133.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7654)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 275, 511)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1167)
[M::mem_pestat] mean and std.dev: (326.07, 221.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1495)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 710466 sequences (100000166 bp) in 2.287 CPU sec, 2.301 real sec...
[M::mem_process_seqs] Processed 712672 reads in 245.617 CPU sec, 7.974 real sec
[M::mem_process_seqs] Processed 711492 reads in 175.376 CPU sec, 5.673 real sec
sorting block 78, #reads = 1067429 mem = 536880022 peak = 1071050752
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (85, 282871, 53, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 358, 1210)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3162)
[M::mem_pestat] mean and std.dev: (625.63, 601.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4138)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 709544 sequences (100000056 bp) in 2.960 CPU sec, 3.273 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (144, 209, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 627)
[M::mem_pestat] mean and std.dev: (234.09, 116.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 788)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (107, 317, 567)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1487)
[M::mem_pestat] mean and std.dev: (355.22, 297.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1947)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 386, 1427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3893)
[M::mem_pestat] mean and std.dev: (744.42, 869.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5126)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708304 sequences (100000141 bp) in 2.360 CPU sec, 2.374 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 283076, 42, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 322, 1218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3272)
[M::mem_pestat] mean and std.dev: (648.47, 747.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4299)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 210, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 624)
[M::mem_pestat] mean and std.dev: (234.23, 116.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 784)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (104, 525, 1078)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3026)
[M::mem_pestat] mean and std.dev: (699.61, 682.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4000)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (278, 442, 1140)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2864)
[M::mem_pestat] mean and std.dev: (759.12, 676.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3726)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 711026 reads in 236.324 CPU sec, 7.593 real sec
sorting block 79, #reads = 1068310 mem = 536879110 peak = 1071050752
[M::mem_process_seqs] Processed 710466 reads in 168.285 CPU sec, 5.418 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 282973, 45, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 407, 1362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3674)
[M::mem_pestat] mean and std.dev: (794.29, 812.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4830)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 211, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 631)
[M::mem_pestat] mean and std.dev: (236.29, 117.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 793)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (403, 650, 1237)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2905)
[M::mem_pestat] mean and std.dev: (768.05, 614.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3739)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (279, 352, 1314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3384)
[M::mem_pestat] mean and std.dev: (622.68, 628.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4419)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707652 sequences (100000216 bp) in 2.726 CPU sec, 3.057 real sec...
sorting block 80, #reads = 1067918 mem = 536880687 peak = 1072066560
[M::process] read 706816 sequences (100000152 bp) in 2.239 CPU sec, 2.326 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 282770, 33, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 260, 688)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1670)
[M::mem_pestat] mean and std.dev: (392.05, 343.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2161)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 215, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 645)
[M::mem_pestat] mean and std.dev: (240.02, 119.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 811)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (420, 619, 1407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3381)
[M::mem_pestat] mean and std.dev: (872.94, 721.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4368)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (272, 528, 2626)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7334)
[M::mem_pestat] mean and std.dev: (1314.75, 1454.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9688)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 709544 reads in 231.336 CPU sec, 7.506 real sec
[M::mem_process_seqs] Processed 708304 reads in 164.945 CPU sec, 5.307 real sec
sorting block 81, #reads = 1069018 mem = 536881348 peak = 1072066560
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 281681, 43, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 361, 714)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1758)
[M::mem_pestat] mean and std.dev: (434.44, 370.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2280)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 215, 314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 648)
[M::mem_pestat] mean and std.dev: (240.57, 119.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 815)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 334, 1306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3478)
[M::mem_pestat] mean and std.dev: (699.59, 681.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4564)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 319, 721)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1815)
[M::mem_pestat] mean and std.dev: (456.06, 378.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2362)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706230 sequences (100000211 bp) in 2.586 CPU sec, 2.797 real sec...
[M::process] read 705474 sequences (100000000 bp) in 2.258 CPU sec, 2.265 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (83, 281877, 45, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (304, 406, 1016)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2440)
[M::mem_pestat] mean and std.dev: (507.39, 397.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3152)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 218, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 659)
[M::mem_pestat] mean and std.dev: (243.74, 122.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 829)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 619, 1150)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2974)
[M::mem_pestat] mean and std.dev: (543.24, 371.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3886)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 383, 684)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1570)
[M::mem_pestat] mean and std.dev: (412.45, 296.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2013)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707652 reads in 225.676 CPU sec, 7.247 real sec
[M::mem_process_seqs] Processed 706816 reads in 161.970 CPU sec, 5.223 real sec
sorting block 82, #reads = 1068917 mem = 536880376 peak = 1072066560
[M::process] read 473662 sequences (67066088 bp) in 2.180 CPU sec, 2.409 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 280896, 46, 86)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 322, 1233)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3311)
[M::mem_pestat] mean and std.dev: (629.64, 650.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4350)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 219, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 659)
[M::mem_pestat] mean and std.dev: (243.86, 121.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 829)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 552, 1155)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3167)
[M::mem_pestat] mean and std.dev: (568.82, 570.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4173)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 304, 933)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2321)
[M::mem_pestat] mean and std.dev: (525.14, 506.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3015)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 280940, 50, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 301, 609)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1429)
[M::mem_pestat] mean and std.dev: (352.65, 243.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1839)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 220, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 657)
[M::mem_pestat] mean and std.dev: (244.44, 120.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 826)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (512, 699, 1519)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3533)
[M::mem_pestat] mean and std.dev: (897.96, 709.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4540)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 408, 1014)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2628)
[M::mem_pestat] mean and std.dev: (574.22, 542.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3435)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706230 reads in 223.559 CPU sec, 7.286 real sec
sorting block 83, #reads = 1068757 mem = 536884309 peak = 1072066560
[M::mem_process_seqs] Processed 705474 reads in 161.745 CPU sec, 5.294 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 188400, 38, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (249, 598, 1204)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3114)
[M::mem_pestat] mean and std.dev: (642.46, 490.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4069)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 218, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 650)
[M::mem_pestat] mean and std.dev: (242.49, 119.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 817)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 629, 1288)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3432)
[M::mem_pestat] mean and std.dev: (651.29, 522.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4504)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 513, 1725)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4749)
[M::mem_pestat] mean and std.dev: (969.55, 872.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6261)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 84, #reads = 1065840 mem = 536876932 peak = 1146634240
[M::mem_process_seqs] Processed 473662 reads in 91.757 CPU sec, 3.141 real sec
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000c06f2
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: INTEL(R) XEON(R) PLATINUM 8559C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 90442348
overall: 71043817472 mem 18084.029 user 342.150 sys 610.621 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1136_3WJ-T1-TDNA-1_A23MHWWLT4_1.L006\tPU:L006\tSM:1136_3WJ-T1-TDNA-1_A23MHWWLT4_1\tLB:1136_3WJ-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1136_3WJ-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1136_3WJ-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 610.658 sec; CPU: 18426.183 sec
sorting block 85, #reads = 497118 mem = 250984019 peak = 1146634240
uniq header count 1
merging 86 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000c06f2
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: INTEL(R) XEON(R) PLATINUM 8559C
threads: 31 max 192
algo: util-sort
license: sentieon:util=1
output file size: 5476382309
output reads: 91307316
bam_mem_sort: 86 calls 57.493 user 1.097 sys 60.075 real
bam_write: 86 calls 66.366 user 4.396 sys 144.999 real
execute: 1 calls 36.037 user 2.082 sys 656.831 real
merge_files: 1 calls 36.019 user 2.045 sys 45.732 real
parse_chunk: 1368 calls 83.106 user 20.386 sys 134.183 real
read_chunk: 3709 calls 51.046 user 20.606 sys 566.364 real
sort_block: 1 calls 33.493 user 19.880 sys 541.104 real
write_chunk: 2339 calls 35.356 user 1.721 sys 44.324 real
overall: 3372613632 mem 1713.786 user 65.039 sys 656.854 real
ls: cannot access '*.cram': No such file or directory