.command.log - Workdir - DAQ:SENTIEON_BWAMEM (1136_4Z5-T1-TDNA-1_A23MHWWLT4_1;L002;0001)

File Info

Filename: .command.log
Full Path: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/0c/08a2fa6f7cb8b266cd92921965d69f/.command.log
Size: 454.8 KB
Task: DAQ:SENTIEON_BWAMEM (1136_4Z5-T1-TDNA-1_A23MHWWLT4_1;L002;0001)
Attempt
Content

  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/55/b25d7521455dd0a232796039286487/1136_4Z5-T1-TDNA-1_A23MHWWLT4_1/1136_4Z5-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/0c/08a2fa6f7cb8b266cd92921965d69f/.command.sh
  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta.fai
  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/BWAIndex
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/55/b25d7521455dd0a232796039286487/1136_4Z5-T1-TDNA-1_A23MHWWLT4_1/1136_4Z5-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/0c/08a2fa6f7cb8b266cd92921965d69f/.command.run
==> STAGING COMPLETE (7 inputs)

cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1136_4Z5-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 1875.677 CPU sec, 69.284 real sec
[M::process] read 731128 sequences (100000165 bp) in 1.708 CPU sec, 1.710 real sec...
[M::process] read 730318 sequences (100000201 bp) in 1.907 CPU sec, 1.913 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 299634, 52, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 442, 981)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2539)
[M::mem_pestat] mean and std.dev: (582.17, 469.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3318)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 181, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 521)
[M::mem_pestat] mean and std.dev: (201.18, 95.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 652)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (276, 546, 1418)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3702)
[M::mem_pestat] mean and std.dev: (726.62, 674.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4844)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 226, 749)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1931)
[M::mem_pestat] mean and std.dev: (418.30, 394.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2522)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 729226 sequences (100000130 bp) in 1.863 CPU sec, 1.872 real sec...
[M::process] read 728132 sequences (100000269 bp) in 1.894 CPU sec, 1.923 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 299161, 47, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (267, 529, 1693)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4545)
[M::mem_pestat] mean and std.dev: (937.10, 988.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5971)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 182, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 525)
[M::mem_pestat] mean and std.dev: (202.33, 96.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 657)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (112, 458, 1018)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2830)
[M::mem_pestat] mean and std.dev: (519.44, 487.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3736)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 331, 1301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3457)
[M::mem_pestat] mean and std.dev: (678.60, 724.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4535)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 731128 reads in 219.260 CPU sec, 6.942 real sec
[M::mem_process_seqs] Processed 730318 reads in 150.921 CPU sec, 4.837 real sec
sorting block 0, #reads = 1097894 mem = 536879070 peak = 605134848
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 299273, 41, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 333, 1280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3414)
[M::mem_pestat] mean and std.dev: (784.07, 861.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4481)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 184, 264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 532)
[M::mem_pestat] mean and std.dev: (204.49, 97.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 666)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (470, 705, 1292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2936)
[M::mem_pestat] mean and std.dev: (734.08, 475.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3758)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 250, 532)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1242)
[M::mem_pestat] mean and std.dev: (304.14, 219.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1597)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727570 sequences (100000208 bp) in 2.827 CPU sec, 3.172 real sec...
[M::process] read 727252 sequences (100000181 bp) in 2.070 CPU sec, 2.079 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 298569, 51, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (287, 675, 1347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3467)
[M::mem_pestat] mean and std.dev: (917.24, 841.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4527)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 185, 267)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 541)
[M::mem_pestat] mean and std.dev: (206.44, 99.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 678)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (637, 997, 1317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2677)
[M::mem_pestat] mean and std.dev: (884.87, 573.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3357)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 491, 922)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2366)
[M::mem_pestat] mean and std.dev: (640.20, 568.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3088)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 729226 reads in 212.187 CPU sec, 6.768 real sec
[M::mem_process_seqs] Processed 728132 reads in 148.751 CPU sec, 4.765 real sec
sorting block 1, #reads = 1097932 mem = 536881620 peak = 763994112
[M::process] read 727486 sequences (100000095 bp) in 3.006 CPU sec, 3.256 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 298588, 37, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 335, 720)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1870)
[M::mem_pestat] mean and std.dev: (420.10, 379.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2445)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 186, 269)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 545)
[M::mem_pestat] mean and std.dev: (207.68, 99.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 683)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (356, 977, 1453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3647)
[M::mem_pestat] mean and std.dev: (845.19, 663.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4744)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 287, 1392)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3866)
[M::mem_pestat] mean and std.dev: (795.83, 910.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5103)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726994 sequences (100000191 bp) in 2.213 CPU sec, 2.216 real sec...
[M::mem_process_seqs] Processed 727252 reads in 120.169 CPU sec, 3.827 real sec
sorting block 2, #reads = 1095527 mem = 536884472 peak = 810590208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 298921, 41, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 466, 758)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1894)
[M::mem_pestat] mean and std.dev: (520.41, 441.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2462)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 186, 268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 542)
[M::mem_pestat] mean and std.dev: (207.17, 99.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 679)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (70, 490, 1430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4150)
[M::mem_pestat] mean and std.dev: (733.77, 808.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5510)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 485, 1081)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2909)
[M::mem_pestat] mean and std.dev: (641.70, 686.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3823)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 298264, 57, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 347, 1084)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2806)
[M::mem_pestat] mean and std.dev: (570.02, 536.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3667)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 186, 269)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 545)
[M::mem_pestat] mean and std.dev: (207.59, 100.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 683)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (311, 501, 878)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2012)
[M::mem_pestat] mean and std.dev: (549.54, 390.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2579)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 543, 1368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3706)
[M::mem_pestat] mean and std.dev: (733.37, 647.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4875)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 727570 reads in 328.444 CPU sec, 10.520 real sec
[M::process] read 726382 sequences (100000123 bp) in 2.683 CPU sec, 2.725 real sec...
[M::mem_process_seqs] Processed 727486 reads in 180.042 CPU sec, 5.831 real sec
sorting block 3, #reads = 1095893 mem = 536879205 peak = 810590208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 298220, 49, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 305, 725)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1805)
[M::mem_pestat] mean and std.dev: (441.91, 380.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2345)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 187, 271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 551)
[M::mem_pestat] mean and std.dev: (209.01, 101.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 691)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (477, 788, 1936)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4854)
[M::mem_pestat] mean and std.dev: (1180.21, 1018.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6313)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (277, 455, 999)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2443)
[M::mem_pestat] mean and std.dev: (536.62, 377.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3165)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725708 sequences (100000157 bp) in 3.742 CPU sec, 4.171 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 297762, 29, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 363, 759)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1945)
[M::mem_pestat] mean and std.dev: (442.03, 386.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2538)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 187, 271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 549)
[M::mem_pestat] mean and std.dev: (209.36, 101.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 688)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (334, 564, 795)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1717)
[M::mem_pestat] mean and std.dev: (533.43, 296.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2178)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 336, 680)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1676)
[M::mem_pestat] mean and std.dev: (374.10, 261.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2174)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 726994 reads in 212.883 CPU sec, 6.829 real sec
[M::mem_process_seqs] Processed 726382 reads in 152.211 CPU sec, 4.824 real sec
[M::process] read 724948 sequences (100000120 bp) in 2.873 CPU sec, 2.990 real sec...
sorting block 4, #reads = 1096305 mem = 536880418 peak = 810590208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 297883, 40, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 303, 734)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1836)
[M::mem_pestat] mean and std.dev: (413.24, 387.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2387)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 188, 272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 552)
[M::mem_pestat] mean and std.dev: (210.00, 101.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 692)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (348, 630, 1178)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2838)
[M::mem_pestat] mean and std.dev: (658.58, 465.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3668)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 348, 806)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2032)
[M::mem_pestat] mean and std.dev: (530.62, 526.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2645)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724810 sequences (100000285 bp) in 3.047 CPU sec, 3.597 real sec...
sorting block 5, #reads = 1095956 mem = 536879261 peak = 851939328
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 297954, 45, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 356, 1608)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4398)
[M::mem_pestat] mean and std.dev: (946.29, 1051.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5793)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 189, 273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 553)
[M::mem_pestat] mean and std.dev: (210.93, 102.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 693)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 773, 1875)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5337)
[M::mem_pestat] mean and std.dev: (879.00, 981.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7068)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 330, 932)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2420)
[M::mem_pestat] mean and std.dev: (522.60, 528.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3164)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 725708 reads in 216.105 CPU sec, 7.025 real sec
[M::process] read 724588 sequences (100000010 bp) in 2.802 CPU sec, 2.918 real sec...
[M::mem_process_seqs] Processed 724948 reads in 155.643 CPU sec, 4.990 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 297857, 52, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 601, 1444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3974)
[M::mem_pestat] mean and std.dev: (805.45, 761.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5239)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 189, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 556)
[M::mem_pestat] mean and std.dev: (211.00, 101.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 697)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (105, 446, 992)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2766)
[M::mem_pestat] mean and std.dev: (492.47, 488.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3653)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 506, 1031)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2623)
[M::mem_pestat] mean and std.dev: (562.50, 405.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3419)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 6, #reads = 1096390 mem = 536882012 peak = 851939328
[M::process] read 724416 sequences (100000002 bp) in 3.525 CPU sec, 4.133 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 297461, 39, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 602, 1774)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4836)
[M::mem_pestat] mean and std.dev: (742.56, 626.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6367)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 189, 273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 553)
[M::mem_pestat] mean and std.dev: (210.86, 101.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 693)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (97, 218, 767)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2107)
[M::mem_pestat] mean and std.dev: (380.86, 463.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2777)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 314, 572)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1340)
[M::mem_pestat] mean and std.dev: (386.49, 284.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1724)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724810 reads in 216.150 CPU sec, 7.040 real sec
[M::mem_process_seqs] Processed 724588 reads in 153.636 CPU sec, 4.953 real sec
[M::process] read 723646 sequences (100000231 bp) in 2.797 CPU sec, 3.092 real sec...
sorting block 7, #reads = 1094251 mem = 536880234 peak = 851939328
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 297516, 39, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 273, 989)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2683)
[M::mem_pestat] mean and std.dev: (563.52, 509.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3530)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 559)
[M::mem_pestat] mean and std.dev: (211.80, 102.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 701)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 573, 1884)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5184)
[M::mem_pestat] mean and std.dev: (1026.22, 1204.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6834)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 263, 879)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2271)
[M::mem_pestat] mean and std.dev: (398.07, 398.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2967)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723436 sequences (100000000 bp) in 3.485 CPU sec, 4.072 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 297128, 34, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 322, 981)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2643)
[M::mem_pestat] mean and std.dev: (507.41, 560.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3474)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 190, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 554)
[M::mem_pestat] mean and std.dev: (211.62, 101.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 694)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (65, 379, 1162)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3356)
[M::mem_pestat] mean and std.dev: (559.83, 788.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4453)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (334, 615, 978)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2266)
[M::mem_pestat] mean and std.dev: (625.08, 443.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2910)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724416 reads in 218.396 CPU sec, 7.128 real sec
[M::mem_process_seqs] Processed 723646 reads in 154.711 CPU sec, 5.028 real sec
sorting block 8, #reads = 1095476 mem = 536879886 peak = 851939328
[M::process] read 723540 sequences (100000139 bp) in 3.082 CPU sec, 3.378 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 296623, 44, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 399, 844)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2116)
[M::mem_pestat] mean and std.dev: (478.28, 335.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2752)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 190, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 554)
[M::mem_pestat] mean and std.dev: (211.72, 101.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 694)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (408, 727, 1326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3162)
[M::mem_pestat] mean and std.dev: (693.92, 482.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4080)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 377, 765)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1901)
[M::mem_pestat] mean and std.dev: (466.04, 363.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2469)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723766 sequences (100000169 bp) in 3.626 CPU sec, 4.040 real sec...
sorting block 9, #reads = 1093404 mem = 536879155 peak = 851939328
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 296964, 45, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 234, 745)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1915)
[M::mem_pestat] mean and std.dev: (486.67, 508.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2523)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 189, 273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 551)
[M::mem_pestat] mean and std.dev: (210.97, 101.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 690)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 809, 1480)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4000)
[M::mem_pestat] mean and std.dev: (835.84, 638.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5260)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 344, 504)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1032)
[M::mem_pestat] mean and std.dev: (315.52, 125.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1296)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723436 reads in 223.226 CPU sec, 7.350 real sec
[M::mem_process_seqs] Processed 723540 reads in 156.091 CPU sec, 5.152 real sec
[M::process] read 724248 sequences (100000273 bp) in 3.465 CPU sec, 3.880 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 297255, 38, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (274, 410, 1113)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2791)
[M::mem_pestat] mean and std.dev: (654.04, 678.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3630)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 190, 273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 551)
[M::mem_pestat] mean and std.dev: (211.17, 101.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 690)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 459, 1014)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2702)
[M::mem_pestat] mean and std.dev: (607.47, 609.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3546)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 325, 603)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1437)
[M::mem_pestat] mean and std.dev: (349.37, 196.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1854)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 10, #reads = 1092456 mem = 536877303 peak = 851939328
[M::process] read 723558 sequences (100000156 bp) in 3.486 CPU sec, 3.973 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 297232, 41, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 413, 1217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3267)
[M::mem_pestat] mean and std.dev: (456.60, 411.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4292)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 189, 272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 550)
[M::mem_pestat] mean and std.dev: (210.09, 100.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 689)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 672, 1084)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2846)
[M::mem_pestat] mean and std.dev: (676.33, 552.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3727)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 337, 751)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1831)
[M::mem_pestat] mean and std.dev: (442.00, 405.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2371)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723766 reads in 224.451 CPU sec, 7.444 real sec
[M::mem_process_seqs] Processed 724248 reads in 157.436 CPU sec, 5.228 real sec
[M::process] read 724038 sequences (100000154 bp) in 4.068 CPU sec, 4.483 real sec...
sorting block 11, #reads = 1092992 mem = 536877960 peak = 851939328
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 296668, 36, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 402, 1784)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4946)
[M::mem_pestat] mean and std.dev: (952.10, 1198.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6527)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 189, 272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 548)
[M::mem_pestat] mean and std.dev: (210.20, 100.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 686)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 553, 1792)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5080)
[M::mem_pestat] mean and std.dev: (1153.83, 1367.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6724)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 522, 1512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4056)
[M::mem_pestat] mean and std.dev: (723.05, 616.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5328)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 296755, 34, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 235, 1276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3488)
[M::mem_pestat] mean and std.dev: (554.98, 662.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4594)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 190, 273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 551)
[M::mem_pestat] mean and std.dev: (211.08, 101.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 690)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 622, 1323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3675)
[M::mem_pestat] mean and std.dev: (691.37, 637.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4851)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 348, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 869)
[M::mem_pestat] mean and std.dev: (347.02, 172.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1073)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723474 sequences (100000000 bp) in 3.322 CPU sec, 3.603 real sec...
[M::mem_process_seqs] Processed 723558 reads in 226.320 CPU sec, 7.487 real sec
[M::mem_process_seqs] Processed 724038 reads in 158.383 CPU sec, 5.219 real sec
sorting block 12, #reads = 1093391 mem = 536877774 peak = 851939328
[M::process] read 723016 sequences (100000238 bp) in 3.396 CPU sec, 3.735 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 297065, 42, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 428, 1713)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4721)
[M::mem_pestat] mean and std.dev: (733.64, 828.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6225)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 190, 273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 551)
[M::mem_pestat] mean and std.dev: (211.27, 101.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 690)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 549, 1748)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4742)
[M::mem_pestat] mean and std.dev: (922.71, 875.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6239)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (259, 516, 850)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2032)
[M::mem_pestat] mean and std.dev: (523.73, 332.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2623)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723474 reads in 126.860 CPU sec, 4.273 real sec
[M::process] read 723002 sequences (100000283 bp) in 3.759 CPU sec, 4.220 real sec...
sorting block 13, #reads = 1093588 mem = 536879987 peak = 851939328
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 296962, 41, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (311, 586, 1004)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2390)
[M::mem_pestat] mean and std.dev: (612.29, 450.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3083)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 190, 273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 551)
[M::mem_pestat] mean and std.dev: (211.28, 100.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 690)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 576, 1117)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3045)
[M::mem_pestat] mean and std.dev: (604.21, 577.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4009)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 521, 1364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3692)
[M::mem_pestat] mean and std.dev: (846.77, 812.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4856)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723016 reads in 155.699 CPU sec, 5.373 real sec
[M::process] read 722570 sequences (100000197 bp) in 3.631 CPU sec, 4.031 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 297336, 29, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 325, 810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2058)
[M::mem_pestat] mean and std.dev: (497.15, 467.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2682)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 191, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 554)
[M::mem_pestat] mean and std.dev: (211.77, 101.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 694)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (277, 402, 1343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3475)
[M::mem_pestat] mean and std.dev: (695.48, 751.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4541)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (332, 491, 968)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2240)
[M::mem_pestat] mean and std.dev: (645.80, 477.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2876)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 14, #reads = 1092854 mem = 536877221 peak = 851939328
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 296498, 42, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 312, 1263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3397)
[M::mem_pestat] mean and std.dev: (744.59, 881.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4464)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 191, 275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 557)
[M::mem_pestat] mean and std.dev: (212.47, 101.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 698)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 622, 1230)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3394)
[M::mem_pestat] mean and std.dev: (752.62, 687.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4476)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 387, 652)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1468)
[M::mem_pestat] mean and std.dev: (453.33, 304.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1876)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721880 sequences (100000105 bp) in 3.552 CPU sec, 3.941 real sec...
[M::mem_process_seqs] Processed 723002 reads in 263.419 CPU sec, 8.897 real sec
[M::mem_process_seqs] Processed 722570 reads in 157.040 CPU sec, 5.287 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 296446, 54, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 304, 1399)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3881)
[M::mem_pestat] mean and std.dev: (470.19, 591.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5122)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 192, 276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 558)
[M::mem_pestat] mean and std.dev: (213.36, 101.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 699)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (19, 333, 1455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4327)
[M::mem_pestat] mean and std.dev: (740.18, 1010.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5763)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 323, 640)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1540)
[M::mem_pestat] mean and std.dev: (417.31, 332.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1990)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720660 sequences (100000203 bp) in 3.711 CPU sec, 4.072 real sec...
sorting block 15, #reads = 1093224 mem = 536878204 peak = 851939328
[M::mem_process_seqs] Processed 721880 reads in 130.057 CPU sec, 4.373 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 296096, 31, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 417, 1271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3323)
[M::mem_pestat] mean and std.dev: (706.11, 695.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4349)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 194, 281)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 571)
[M::mem_pestat] mean and std.dev: (216.48, 104.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 716)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (409, 662, 2142)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5608)
[M::mem_pestat] mean and std.dev: (1038.58, 855.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7341)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 329, 849)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2153)
[M::mem_pestat] mean and std.dev: (376.53, 317.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2805)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721696 sequences (100000097 bp) in 3.700 CPU sec, 4.234 real sec...
[M::mem_process_seqs] Processed 720660 reads in 121.085 CPU sec, 4.156 real sec
sorting block 16, #reads = 1093415 mem = 536878139 peak = 851939328
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 296402, 55, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (283, 391, 934)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2236)
[M::mem_pestat] mean and std.dev: (568.97, 390.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2887)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 192, 277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 561)
[M::mem_pestat] mean and std.dev: (213.68, 101.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 703)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 428, 1104)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3030)
[M::mem_pestat] mean and std.dev: (613.60, 641.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3993)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 340, 1530)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4258)
[M::mem_pestat] mean and std.dev: (664.86, 794.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5622)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721542 sequences (100000110 bp) in 3.534 CPU sec, 3.915 real sec...
[M::mem_process_seqs] Processed 721696 reads in 126.246 CPU sec, 4.522 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 296627, 34, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 299, 830)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2186)
[M::mem_pestat] mean and std.dev: (515.57, 583.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2864)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 193, 278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 564)
[M::mem_pestat] mean and std.dev: (214.50, 102.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 707)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 438, 628)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1432)
[M::mem_pestat] mean and std.dev: (405.83, 216.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1834)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 348, 1001)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2631)
[M::mem_pestat] mean and std.dev: (622.68, 624.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3446)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720710 sequences (100000201 bp) in 3.673 CPU sec, 4.028 real sec...
sorting block 17, #reads = 1093147 mem = 536884857 peak = 851939328
[M::mem_process_seqs] Processed 721542 reads in 127.146 CPU sec, 4.492 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 296251, 48, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 291, 991)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2629)
[M::mem_pestat] mean and std.dev: (537.95, 570.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3448)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 194, 278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 562)
[M::mem_pestat] mean and std.dev: (215.07, 102.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 704)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 814, 1427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3931)
[M::mem_pestat] mean and std.dev: (727.00, 631.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5183)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 342, 1034)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2736)
[M::mem_pestat] mean and std.dev: (541.06, 477.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3587)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720496 sequences (100000191 bp) in 3.414 CPU sec, 3.664 real sec...
[M::mem_process_seqs] Processed 720710 reads in 124.937 CPU sec, 4.237 real sec
sorting block 18, #reads = 1093422 mem = 536882175 peak = 851939328
[M::process] read 720458 sequences (100000248 bp) in 2.996 CPU sec, 3.305 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 295681, 47, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 385, 572)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1280)
[M::mem_pestat] mean and std.dev: (349.72, 201.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1634)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 194, 279)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 565)
[M::mem_pestat] mean and std.dev: (215.22, 102.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 708)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 462, 1041)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2671)
[M::mem_pestat] mean and std.dev: (684.63, 642.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3486)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 450, 1703)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4693)
[M::mem_pestat] mean and std.dev: (883.33, 836.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6188)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 19, #reads = 1092564 mem = 536882380 peak = 854872064
[M::process] read 720424 sequences (100000215 bp) in 3.560 CPU sec, 3.808 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 295979, 43, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 321, 685)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1651)
[M::mem_pestat] mean and std.dev: (439.37, 351.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2134)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 195, 280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 568)
[M::mem_pestat] mean and std.dev: (215.91, 103.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 712)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (361, 478, 821)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1741)
[M::mem_pestat] mean and std.dev: (573.02, 393.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2201)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 373, 807)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2035)
[M::mem_pestat] mean and std.dev: (511.26, 458.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2649)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 720496 reads in 223.403 CPU sec, 7.382 real sec
[M::mem_process_seqs] Processed 720458 reads in 158.575 CPU sec, 5.259 real sec
[M::process] read 720272 sequences (100000072 bp) in 2.643 CPU sec, 3.022 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 296033, 36, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (296, 511, 1431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3701)
[M::mem_pestat] mean and std.dev: (863.46, 926.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4836)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 195, 280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 568)
[M::mem_pestat] mean and std.dev: (215.86, 103.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 712)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (583, 843, 2129)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5221)
[M::mem_pestat] mean and std.dev: (1190.88, 937.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6767)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 578, 1939)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5395)
[M::mem_pestat] mean and std.dev: (903.22, 867.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7123)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 20, #reads = 1092019 mem = 536879507 peak = 854872064
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 296194, 56, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 321, 627)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1475)
[M::mem_pestat] mean and std.dev: (366.87, 302.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1899)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 719962 sequences (100000266 bp) in 3.816 CPU sec, 4.277 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (136, 195, 280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 568)
[M::mem_pestat] mean and std.dev: (216.02, 103.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 712)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 660, 1337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3587)
[M::mem_pestat] mean and std.dev: (806.69, 755.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4712)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 786, 1285)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3455)
[M::mem_pestat] mean and std.dev: (875.98, 777.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4540)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 720424 reads in 223.025 CPU sec, 7.322 real sec
[M::mem_process_seqs] Processed 720272 reads in 156.917 CPU sec, 5.105 real sec
[M::process] read 722916 sequences (100000005 bp) in 3.335 CPU sec, 3.687 real sec...
sorting block 21, #reads = 1092230 mem = 536876954 peak = 854872064
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 296131, 71, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (249, 346, 892)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2178)
[M::mem_pestat] mean and std.dev: (590.61, 520.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2821)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 196, 283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 575)
[M::mem_pestat] mean and std.dev: (217.61, 104.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 721)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (444, 1312, 3085)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8367)
[M::mem_pestat] mean and std.dev: (1883.72, 1842.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11008)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 518, 1308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3520)
[M::mem_pestat] mean and std.dev: (661.32, 630.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4626)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 297059, 37, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 491, 1339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3505)
[M::mem_pestat] mean and std.dev: (776.53, 715.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4588)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 191, 276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 560)
[M::mem_pestat] mean and std.dev: (212.67, 101.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 702)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (350, 972, 2035)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5405)
[M::mem_pestat] mean and std.dev: (1228.22, 1154.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7090)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 671, 1320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3452)
[M::mem_pestat] mean and std.dev: (722.51, 688.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4518)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 730610 sequences (100000089 bp) in 3.447 CPU sec, 3.978 real sec...
[M::mem_process_seqs] Processed 719962 reads in 219.302 CPU sec, 7.197 real sec
sorting block 22, #reads = 1092975 mem = 536878268 peak = 854872064
[M::process] read 729810 sequences (100000168 bp) in 3.203 CPU sec, 3.810 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 299302, 35, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 405, 1029)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2699)
[M::mem_pestat] mean and std.dev: (574.67, 551.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3534)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 182, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 525)
[M::mem_pestat] mean and std.dev: (202.08, 96.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 657)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (112, 493, 980)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2716)
[M::mem_pestat] mean and std.dev: (507.06, 447.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3584)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 414, 714)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1734)
[M::mem_pestat] mean and std.dev: (447.93, 330.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2244)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 730610 reads in 126.119 CPU sec, 4.075 real sec
[M::process] read 729196 sequences (100000216 bp) in 3.461 CPU sec, 3.676 real sec...
sorting block 23, #reads = 1095111 mem = 536882176 peak = 866553856
[M::mem_process_seqs] Processed 722916 reads in 374.669 CPU sec, 12.084 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 298961, 33, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 345, 1292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3428)
[M::mem_pestat] mean and std.dev: (675.38, 667.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4496)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 183, 263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 531)
[M::mem_pestat] mean and std.dev: (203.86, 97.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 665)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (279, 468, 2016)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5490)
[M::mem_pestat] mean and std.dev: (1152.09, 1327.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7227)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (287, 468, 1315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3371)
[M::mem_pestat] mean and std.dev: (737.15, 734.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4399)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 298655, 50, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 433, 869)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2157)
[M::mem_pestat] mean and std.dev: (529.32, 450.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2801)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 184, 265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 535)
[M::mem_pestat] mean and std.dev: (205.06, 98.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 670)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 441, 1581)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4453)
[M::mem_pestat] mean and std.dev: (701.04, 696.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5889)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 341, 1083)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2807)
[M::mem_pestat] mean and std.dev: (664.33, 614.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3669)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728528 sequences (100000240 bp) in 3.384 CPU sec, 4.470 real sec...
[M::mem_process_seqs] Processed 729810 reads in 251.593 CPU sec, 8.119 real sec
[M::mem_process_seqs] Processed 729196 reads in 154.126 CPU sec, 5.024 real sec
sorting block 24, #reads = 1093454 mem = 536877291 peak = 866553856
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 299271, 26, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 406, 1263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3447)
[M::mem_pestat] mean and std.dev: (584.06, 548.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4539)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 185, 266)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 538)
[M::mem_pestat] mean and std.dev: (205.85, 99.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 674)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (87, 468, 822)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2292)
[M::mem_pestat] mean and std.dev: (414.30, 372.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3027)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 333, 829)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2061)
[M::mem_pestat] mean and std.dev: (467.02, 396.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2677)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728194 sequences (100000052 bp) in 3.601 CPU sec, 3.963 real sec...
[M::mem_process_seqs] Processed 728528 reads in 123.992 CPU sec, 4.152 real sec
[M::process] read 727360 sequences (100000259 bp) in 3.530 CPU sec, 3.992 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 298929, 28, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 460, 946)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2476)
[M::mem_pestat] mean and std.dev: (562.17, 487.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3241)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 185, 267)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 541)
[M::mem_pestat] mean and std.dev: (206.48, 99.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 678)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (476, 1079, 1283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2897)
[M::mem_pestat] mean and std.dev: (855.96, 590.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3704)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (273, 461, 1098)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2748)
[M::mem_pestat] mean and std.dev: (690.11, 726.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3596)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 25, #reads = 1097809 mem = 536884271 peak = 866553856
[M::mem_process_seqs] Processed 728194 reads in 121.496 CPU sec, 4.143 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 298613, 40, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 434, 1501)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4087)
[M::mem_pestat] mean and std.dev: (715.31, 851.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5380)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 186, 269)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 545)
[M::mem_pestat] mean and std.dev: (207.30, 99.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 683)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (249, 757, 1258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3276)
[M::mem_pestat] mean and std.dev: (690.94, 605.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4285)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (289, 379, 1044)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2554)
[M::mem_pestat] mean and std.dev: (583.63, 431.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3309)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726726 sequences (100000240 bp) in 3.673 CPU sec, 4.132 real sec...
[M::mem_process_seqs] Processed 727360 reads in 123.200 CPU sec, 4.171 real sec
sorting block 26, #reads = 1097597 mem = 536883756 peak = 866553856
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 298614, 39, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 289, 815)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2175)
[M::mem_pestat] mean and std.dev: (459.21, 489.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2855)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 187, 270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 548)
[M::mem_pestat] mean and std.dev: (208.59, 100.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 687)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 473, 1024)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2784)
[M::mem_pestat] mean and std.dev: (687.42, 661.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3664)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 364, 962)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2450)
[M::mem_pestat] mean and std.dev: (563.99, 551.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3194)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726140 sequences (100000257 bp) in 3.508 CPU sec, 3.837 real sec...
[M::mem_process_seqs] Processed 726726 reads in 124.009 CPU sec, 4.277 real sec
sorting block 27, #reads = 1096352 mem = 536878483 peak = 887877632
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 298386, 45, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 527, 1029)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2669)
[M::mem_pestat] mean and std.dev: (643.74, 573.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3489)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 188, 273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 555)
[M::mem_pestat] mean and std.dev: (210.30, 102.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 696)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (428, 781, 1440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3464)
[M::mem_pestat] mean and std.dev: (663.08, 542.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4476)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 346, 1080)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2782)
[M::mem_pestat] mean and std.dev: (626.97, 588.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3633)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726284 sequences (100000125 bp) in 3.366 CPU sec, 3.725 real sec...
[M::mem_process_seqs] Processed 726140 reads in 124.915 CPU sec, 4.176 real sec
[M::process] read 726168 sequences (100000206 bp) in 3.195 CPU sec, 3.744 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 298342, 33, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 540, 888)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2242)
[M::mem_pestat] mean and std.dev: (545.23, 466.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2919)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 187, 271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 549)
[M::mem_pestat] mean and std.dev: (209.17, 101.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 688)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (104, 560, 1413)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4031)
[M::mem_pestat] mean and std.dev: (837.67, 902.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5340)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (265, 526, 1128)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2854)
[M::mem_pestat] mean and std.dev: (634.92, 525.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3717)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 726284 reads in 124.330 CPU sec, 4.191 real sec
sorting block 28, #reads = 1096992 mem = 536882238 peak = 887877632
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 297941, 50, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 346, 1543)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4299)
[M::mem_pestat] mean and std.dev: (779.78, 952.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5677)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 188, 272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 552)
[M::mem_pestat] mean and std.dev: (210.08, 101.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 692)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (518, 848, 2435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6269)
[M::mem_pestat] mean and std.dev: (1420.10, 1274.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8186)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 287, 631)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1511)
[M::mem_pestat] mean and std.dev: (365.07, 243.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1951)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725218 sequences (100000097 bp) in 3.625 CPU sec, 4.165 real sec...
[M::mem_process_seqs] Processed 726168 reads in 122.248 CPU sec, 4.171 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 298002, 38, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 283, 742)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1852)
[M::mem_pestat] mean and std.dev: (367.19, 314.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2407)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 188, 273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 555)
[M::mem_pestat] mean and std.dev: (210.83, 102.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 696)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 660, 2049)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5757)
[M::mem_pestat] mean and std.dev: (1222.38, 1362.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7611)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 560, 1786)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4934)
[M::mem_pestat] mean and std.dev: (1057.60, 1235.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6508)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 29, #reads = 1096576 mem = 536890039 peak = 888950784
[M::process] read 725004 sequences (100000194 bp) in 4.218 CPU sec, 4.656 real sec...
[M::mem_process_seqs] Processed 725218 reads in 122.469 CPU sec, 4.132 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 297566, 60, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 325, 536)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1126)
[M::mem_pestat] mean and std.dev: (383.54, 237.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1421)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 189, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 556)
[M::mem_pestat] mean and std.dev: (211.23, 102.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 697)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 492, 1385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3699)
[M::mem_pestat] mean and std.dev: (720.79, 640.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4856)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 492, 1761)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4815)
[M::mem_pestat] mean and std.dev: (996.05, 1157.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6342)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724364 sequences (100000035 bp) in 3.780 CPU sec, 4.151 real sec...
[M::mem_process_seqs] Processed 725004 reads in 122.291 CPU sec, 4.137 real sec
sorting block 30, #reads = 1096048 mem = 536878223 peak = 888950784
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 297524, 53, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 376, 872)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2172)
[M::mem_pestat] mean and std.dev: (576.26, 519.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2822)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 559)
[M::mem_pestat] mean and std.dev: (212.15, 102.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 701)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 380, 587)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1437)
[M::mem_pestat] mean and std.dev: (369.32, 284.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1862)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 540, 1438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3894)
[M::mem_pestat] mean and std.dev: (848.54, 910.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5122)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724144 sequences (100000259 bp) in 3.365 CPU sec, 3.704 real sec...
[M::mem_process_seqs] Processed 724364 reads in 123.083 CPU sec, 4.194 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 297055, 57, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 289, 790)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2048)
[M::mem_pestat] mean and std.dev: (415.04, 389.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2677)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 556)
[M::mem_pestat] mean and std.dev: (211.80, 102.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 697)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 531, 848)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2250)
[M::mem_pestat] mean and std.dev: (461.90, 447.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2951)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 410, 1531)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4079)
[M::mem_pestat] mean and std.dev: (736.50, 705.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5353)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 31, #reads = 1095693 mem = 536878009 peak = 898555904
[M::process] read 724104 sequences (100000110 bp) in 3.811 CPU sec, 4.495 real sec...
[M::mem_process_seqs] Processed 724144 reads in 124.883 CPU sec, 4.195 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 297530, 43, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 314, 706)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1792)
[M::mem_pestat] mean and std.dev: (401.08, 303.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2335)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 556)
[M::mem_pestat] mean and std.dev: (211.59, 102.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 697)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (369, 579, 970)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2172)
[M::mem_pestat] mean and std.dev: (657.41, 466.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2773)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 326, 924)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2482)
[M::mem_pestat] mean and std.dev: (517.87, 537.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3261)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724332 sequences (100000229 bp) in 3.287 CPU sec, 3.655 real sec...
[M::mem_process_seqs] Processed 724104 reads in 122.633 CPU sec, 4.151 real sec
sorting block 32, #reads = 1095384 mem = 536879218 peak = 898555904
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 297980, 39, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 235, 645)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1539)
[M::mem_pestat] mean and std.dev: (322.27, 301.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1986)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 556)
[M::mem_pestat] mean and std.dev: (211.62, 102.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 697)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (131, 581, 1718)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4892)
[M::mem_pestat] mean and std.dev: (876.05, 880.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6479)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 356, 734)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1792)
[M::mem_pestat] mean and std.dev: (411.07, 319.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2321)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723994 sequences (100000281 bp) in 3.971 CPU sec, 4.547 real sec...
[M::mem_process_seqs] Processed 724332 reads in 122.220 CPU sec, 4.130 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 296807, 67, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 309, 1083)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2945)
[M::mem_pestat] mean and std.dev: (530.18, 594.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3876)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 553)
[M::mem_pestat] mean and std.dev: (211.00, 101.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 693)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 563, 1421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3927)
[M::mem_pestat] mean and std.dev: (865.48, 947.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5180)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 332, 1243)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3301)
[M::mem_pestat] mean and std.dev: (766.53, 871.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4330)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 33, #reads = 1093623 mem = 536880350 peak = 898555904
[M::process] read 724656 sequences (100000125 bp) in 3.515 CPU sec, 3.811 real sec...
[M::mem_process_seqs] Processed 723994 reads in 122.005 CPU sec, 4.150 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 297262, 49, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 381, 988)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2490)
[M::mem_pestat] mean and std.dev: (490.52, 417.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3241)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 189, 271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 547)
[M::mem_pestat] mean and std.dev: (209.73, 100.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 685)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 369, 925)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2403)
[M::mem_pestat] mean and std.dev: (453.98, 427.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3142)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 468, 775)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1887)
[M::mem_pestat] mean and std.dev: (465.15, 340.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2443)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724666 sequences (100000213 bp) in 3.203 CPU sec, 3.771 real sec...
[M::mem_process_seqs] Processed 724656 reads in 123.637 CPU sec, 4.208 real sec
sorting block 34, #reads = 1094175 mem = 536877309 peak = 898625536
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 297729, 35, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 402, 1344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3612)
[M::mem_pestat] mean and std.dev: (698.67, 609.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4746)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 188, 272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 550)
[M::mem_pestat] mean and std.dev: (210.03, 101.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 689)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (305, 767, 1834)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4892)
[M::mem_pestat] mean and std.dev: (1009.21, 906.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6421)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 430, 1120)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2906)
[M::mem_pestat] mean and std.dev: (701.80, 735.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3799)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723926 sequences (100000039 bp) in 3.478 CPU sec, 3.845 real sec...
[M::mem_process_seqs] Processed 724666 reads in 124.265 CPU sec, 4.224 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 296486, 42, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (259, 479, 980)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2422)
[M::mem_pestat] mean and std.dev: (636.79, 488.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3143)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 189, 272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 550)
[M::mem_pestat] mean and std.dev: (210.55, 101.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 689)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (378, 731, 1677)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4275)
[M::mem_pestat] mean and std.dev: (727.69, 558.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5574)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (266, 465, 1576)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4196)
[M::mem_pestat] mean and std.dev: (808.26, 909.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5506)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724042 sequences (100000039 bp) in 3.583 CPU sec, 3.886 real sec...
sorting block 35, #reads = 1093225 mem = 536878716 peak = 898625536
[M::mem_process_seqs] Processed 723926 reads in 124.555 CPU sec, 4.248 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 297309, 51, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 394, 1352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3560)
[M::mem_pestat] mean and std.dev: (718.16, 638.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4664)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 724176 sequences (100000153 bp) in 3.348 CPU sec, 3.699 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (133, 189, 272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 550)
[M::mem_pestat] mean and std.dev: (210.34, 100.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 689)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (384, 585, 1042)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2358)
[M::mem_pestat] mean and std.dev: (717.06, 565.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3016)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (296, 481, 1137)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2819)
[M::mem_pestat] mean and std.dev: (670.89, 492.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3660)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724042 reads in 124.104 CPU sec, 4.309 real sec
sorting block 36, #reads = 1093839 mem = 536883200 peak = 898625536
[M::process] read 723578 sequences (100000056 bp) in 3.377 CPU sec, 3.765 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 297452, 44, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 626, 1208)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3198)
[M::mem_pestat] mean and std.dev: (750.52, 612.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4193)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 189, 272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 550)
[M::mem_pestat] mean and std.dev: (210.26, 100.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 689)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 1015, 2708)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7766)
[M::mem_pestat] mean and std.dev: (1462.23, 1344.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10295)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 365, 911)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2271)
[M::mem_pestat] mean and std.dev: (497.45, 420.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2951)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 296785, 46, 81)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (252, 455, 1368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3600)
[M::mem_pestat] mean and std.dev: (679.84, 602.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4716)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 190, 273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 551)
[M::mem_pestat] mean and std.dev: (210.94, 100.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 690)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (109, 579, 1460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4162)
[M::mem_pestat] mean and std.dev: (976.77, 1070.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5513)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 306, 733)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1765)
[M::mem_pestat] mean and std.dev: (393.58, 274.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2281)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723178 sequences (100000285 bp) in 3.405 CPU sec, 3.779 real sec...
sorting block 37, #reads = 1094262 mem = 536879012 peak = 937160704
[M::mem_process_seqs] Processed 724176 reads in 218.905 CPU sec, 7.191 real sec
[M::mem_process_seqs] Processed 723578 reads in 154.973 CPU sec, 5.079 real sec
[M::process] read 722746 sequences (100000299 bp) in 3.373 CPU sec, 3.790 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (79, 296495, 31, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 444, 982)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2564)
[M::mem_pestat] mean and std.dev: (594.24, 533.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3355)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 190, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 554)
[M::mem_pestat] mean and std.dev: (211.79, 101.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 694)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (469, 853, 1137)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2473)
[M::mem_pestat] mean and std.dev: (719.52, 455.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3141)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 431, 839)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2027)
[M::mem_pestat] mean and std.dev: (503.29, 409.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2621)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723178 reads in 124.902 CPU sec, 4.228 real sec
sorting block 38, #reads = 1093337 mem = 536879913 peak = 937160704
[M::process] read 722602 sequences (100000145 bp) in 3.419 CPU sec, 3.607 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 296523, 45, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 230, 650)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1674)
[M::mem_pestat] mean and std.dev: (379.70, 395.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2186)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 190, 273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 551)
[M::mem_pestat] mean and std.dev: (211.26, 100.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 690)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 500, 1037)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2675)
[M::mem_pestat] mean and std.dev: (658.81, 592.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3494)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 377, 859)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2117)
[M::mem_pestat] mean and std.dev: (531.54, 405.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2746)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 296818, 41, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 351, 1010)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2552)
[M::mem_pestat] mean and std.dev: (594.76, 615.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3323)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 191, 275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 557)
[M::mem_pestat] mean and std.dev: (212.51, 101.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 698)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 455, 1114)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2866)
[M::mem_pestat] mean and std.dev: (671.30, 599.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3742)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (261, 549, 1470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3888)
[M::mem_pestat] mean and std.dev: (729.63, 673.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5097)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723398 sequences (100000151 bp) in 3.181 CPU sec, 3.456 real sec...
sorting block 39, #reads = 1093049 mem = 536890525 peak = 937160704
[M::mem_process_seqs] Processed 722746 reads in 248.023 CPU sec, 8.313 real sec
[M::mem_process_seqs] Processed 722602 reads in 154.417 CPU sec, 5.268 real sec
[M::process] read 722410 sequences (100000213 bp) in 2.714 CPU sec, 2.930 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 296665, 41, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 354, 1790)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5026)
[M::mem_pestat] mean and std.dev: (884.41, 1142.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6644)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 190, 275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 557)
[M::mem_pestat] mean and std.dev: (212.04, 102.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 698)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (128, 495, 1451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4097)
[M::mem_pestat] mean and std.dev: (840.19, 975.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5420)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 328, 1569)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4389)
[M::mem_pestat] mean and std.dev: (803.55, 871.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5799)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 40, #reads = 1092276 mem = 536881249 peak = 937160704
[M::process] read 722616 sequences (100000204 bp) in 3.031 CPU sec, 3.369 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 296456, 48, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 361, 1093)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2851)
[M::mem_pestat] mean and std.dev: (665.17, 653.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3730)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 191, 275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 557)
[M::mem_pestat] mean and std.dev: (212.79, 102.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 698)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 831, 1498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4138)
[M::mem_pestat] mean and std.dev: (791.33, 811.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5458)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (260, 636, 975)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2405)
[M::mem_pestat] mean and std.dev: (609.82, 497.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3120)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723398 reads in 218.541 CPU sec, 7.075 real sec
[M::mem_process_seqs] Processed 722410 reads in 155.700 CPU sec, 4.990 real sec
[M::process] read 722068 sequences (100000001 bp) in 2.609 CPU sec, 2.662 real sec...
sorting block 41, #reads = 1093059 mem = 536881060 peak = 937160704
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 296846, 53, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 329, 653)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1617)
[M::mem_pestat] mean and std.dev: (472.46, 399.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2099)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 191, 277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 563)
[M::mem_pestat] mean and std.dev: (213.50, 103.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 706)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 476, 776)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1856)
[M::mem_pestat] mean and std.dev: (497.69, 391.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2396)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 472, 1346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3590)
[M::mem_pestat] mean and std.dev: (765.48, 682.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4712)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721460 sequences (100000035 bp) in 3.182 CPU sec, 3.470 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 296244, 41, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 766, 1757)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4783)
[M::mem_pestat] mean and std.dev: (995.46, 1032.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6296)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 192, 276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 558)
[M::mem_pestat] mean and std.dev: (213.15, 102.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 699)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (356, 668, 1066)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2486)
[M::mem_pestat] mean and std.dev: (640.14, 412.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3196)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 410, 1167)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3041)
[M::mem_pestat] mean and std.dev: (657.26, 610.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3978)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 722616 reads in 215.462 CPU sec, 6.984 real sec
[M::process] read 721102 sequences (100000202 bp) in 2.946 CPU sec, 2.974 real sec...
sorting block 42, #reads = 1092421 mem = 536882919 peak = 937160704
[M::mem_process_seqs] Processed 722068 reads in 157.592 CPU sec, 5.060 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 296374, 43, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 303, 1561)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4235)
[M::mem_pestat] mean and std.dev: (790.47, 955.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5572)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 192, 277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 561)
[M::mem_pestat] mean and std.dev: (213.63, 101.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 703)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (101, 496, 1061)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2981)
[M::mem_pestat] mean and std.dev: (432.63, 394.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3941)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (325, 419, 1217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3001)
[M::mem_pestat] mean and std.dev: (708.16, 574.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3893)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 43, #reads = 1092481 mem = 536883695 peak = 998248448
[M::process] read 721160 sequences (100000196 bp) in 3.812 CPU sec, 4.194 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 296234, 64, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 446, 781)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1903)
[M::mem_pestat] mean and std.dev: (443.67, 325.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2464)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 193, 278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 562)
[M::mem_pestat] mean and std.dev: (214.67, 102.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 704)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 565, 1554)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4182)
[M::mem_pestat] mean and std.dev: (917.29, 964.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5496)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 366, 1889)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5307)
[M::mem_pestat] mean and std.dev: (788.17, 931.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7016)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 721460 reads in 214.196 CPU sec, 6.962 real sec
[M::mem_process_seqs] Processed 721102 reads in 152.674 CPU sec, 4.932 real sec
[M::process] read 720880 sequences (100000103 bp) in 3.209 CPU sec, 3.436 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 296344, 49, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 297, 1209)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3221)
[M::mem_pestat] mean and std.dev: (549.63, 508.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4227)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 194, 280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 568)
[M::mem_pestat] mean and std.dev: (215.74, 103.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 712)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (316, 577, 2856)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7936)
[M::mem_pestat] mean and std.dev: (1428.53, 1610.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10476)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (267, 494, 795)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1851)
[M::mem_pestat] mean and std.dev: (532.61, 381.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2379)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 44, #reads = 1093368 mem = 536879802 peak = 998248448
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 296613, 33, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 262, 557)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1327)
[M::mem_pestat] mean and std.dev: (339.18, 228.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1712)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 194, 280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 568)
[M::mem_pestat] mean and std.dev: (215.77, 104.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 712)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (333, 835, 2544)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6966)
[M::mem_pestat] mean and std.dev: (1149.57, 1144.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9177)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 310, 1718)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4740)
[M::mem_pestat] mean and std.dev: (920.80, 967.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6251)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720852 sequences (100000168 bp) in 4.063 CPU sec, 4.616 real sec...
[M::mem_process_seqs] Processed 721160 reads in 215.995 CPU sec, 7.028 real sec
[M::mem_process_seqs] Processed 720880 reads in 154.548 CPU sec, 4.990 real sec
sorting block 45, #reads = 1091510 mem = 536877199 peak = 998248448
[M::process] read 729784 sequences (100000083 bp) in 3.753 CPU sec, 4.105 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 296459, 46, 97)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 719, 1097)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2905)
[M::mem_pestat] mean and std.dev: (843.40, 718.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3809)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 194, 282)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 574)
[M::mem_pestat] mean and std.dev: (216.88, 105.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 720)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (253, 554, 1362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3580)
[M::mem_pestat] mean and std.dev: (874.47, 804.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4689)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 376, 1249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3329)
[M::mem_pestat] mean and std.dev: (697.43, 675.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4369)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 298732, 31, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 255, 717)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1829)
[M::mem_pestat] mean and std.dev: (413.20, 387.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2385)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 183, 263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 531)
[M::mem_pestat] mean and std.dev: (203.74, 97.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 665)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (123, 433, 1002)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2760)
[M::mem_pestat] mean and std.dev: (569.73, 576.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3639)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 361, 810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1918)
[M::mem_pestat] mean and std.dev: (545.34, 405.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2472)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 730412 sequences (100000260 bp) in 3.508 CPU sec, 4.054 real sec...
[M::mem_process_seqs] Processed 720852 reads in 222.822 CPU sec, 7.290 real sec
[M::mem_process_seqs] Processed 729784 reads in 159.685 CPU sec, 5.155 real sec
sorting block 46, #reads = 1091740 mem = 536877268 peak = 998248448
[M::process] read 729316 sequences (100000239 bp) in 3.363 CPU sec, 3.636 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 298773, 48, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 650, 1259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3387)
[M::mem_pestat] mean and std.dev: (617.45, 540.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4451)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 182, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 525)
[M::mem_pestat] mean and std.dev: (202.31, 96.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 657)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 349, 829)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2185)
[M::mem_pestat] mean and std.dev: (422.84, 406.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2863)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 574, 1171)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3065)
[M::mem_pestat] mean and std.dev: (650.78, 658.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4012)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 298962, 34, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 627, 1017)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2631)
[M::mem_pestat] mean and std.dev: (662.69, 601.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3438)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 184, 264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 532)
[M::mem_pestat] mean and std.dev: (204.32, 97.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 666)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 473, 1001)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2643)
[M::mem_pestat] mean and std.dev: (554.26, 508.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3464)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 376, 1299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3471)
[M::mem_pestat] mean and std.dev: (718.96, 720.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4557)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727944 sequences (100000107 bp) in 3.376 CPU sec, 3.883 real sec...
sorting block 47, #reads = 1094009 mem = 536879722 peak = 998248448
[M::mem_process_seqs] Processed 730412 reads in 219.668 CPU sec, 7.168 real sec
[M::mem_process_seqs] Processed 729316 reads in 154.865 CPU sec, 5.048 real sec
[M::process] read 727586 sequences (100000141 bp) in 3.552 CPU sec, 4.008 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 298794, 38, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 292, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 956)
[M::mem_pestat] mean and std.dev: (300.80, 169.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1207)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 185, 266)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 536)
[M::mem_pestat] mean and std.dev: (205.85, 98.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 671)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 534, 1245)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3283)
[M::mem_pestat] mean and std.dev: (879.44, 935.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4621)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 436, 1002)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2550)
[M::mem_pestat] mean and std.dev: (584.20, 500.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3324)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 48, #reads = 1097821 mem = 536883003 peak = 998248448
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 298908, 42, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 435, 2321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6575)
[M::mem_pestat] mean and std.dev: (908.75, 1061.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8702)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 186, 268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 542)
[M::mem_pestat] mean and std.dev: (207.27, 99.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 679)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (424, 805, 1183)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2701)
[M::mem_pestat] mean and std.dev: (876.18, 696.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3664)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 310, 1103)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2935)
[M::mem_pestat] mean and std.dev: (612.20, 586.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3851)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727214 sequences (100000011 bp) in 3.375 CPU sec, 3.825 real sec...
[M::mem_process_seqs] Processed 727944 reads in 216.946 CPU sec, 7.125 real sec
[M::mem_process_seqs] Processed 727586 reads in 154.732 CPU sec, 5.057 real sec
sorting block 49, #reads = 1096389 mem = 536880485 peak = 998248448
[M::process] read 726468 sequences (100000099 bp) in 3.510 CPU sec, 3.975 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 298931, 49, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 291, 793)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1971)
[M::mem_pestat] mean and std.dev: (525.30, 518.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2599)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 186, 268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 542)
[M::mem_pestat] mean and std.dev: (207.47, 99.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 679)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 544, 1291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3401)
[M::mem_pestat] mean and std.dev: (666.49, 605.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4456)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 395, 1651)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4463)
[M::mem_pestat] mean and std.dev: (737.22, 857.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5869)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (85, 298126, 48, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (257, 430, 1133)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2885)
[M::mem_pestat] mean and std.dev: (671.35, 650.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3761)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 187, 270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 548)
[M::mem_pestat] mean and std.dev: (208.39, 100.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 687)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (121, 472, 1395)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3943)
[M::mem_pestat] mean and std.dev: (722.85, 788.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5217)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 370, 1308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3520)
[M::mem_pestat] mean and std.dev: (684.00, 615.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4626)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725790 sequences (100000032 bp) in 3.724 CPU sec, 4.415 real sec...
[M::mem_process_seqs] Processed 727214 reads in 218.458 CPU sec, 7.145 real sec
[M::mem_process_seqs] Processed 726468 reads in 153.100 CPU sec, 4.991 real sec
sorting block 50, #reads = 1096065 mem = 536877030 peak = 998248448
[M::process] read 725384 sequences (100000215 bp) in 3.127 CPU sec, 3.384 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 298270, 41, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 337, 1581)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4367)
[M::mem_pestat] mean and std.dev: (917.71, 1004.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5760)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 188, 271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 549)
[M::mem_pestat] mean and std.dev: (209.56, 100.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 688)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 475, 1575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4299)
[M::mem_pestat] mean and std.dev: (587.94, 617.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5661)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (368, 1180, 1879)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4901)
[M::mem_pestat] mean and std.dev: (892.55, 653.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6412)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 298153, 43, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 440, 829)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2137)
[M::mem_pestat] mean and std.dev: (434.80, 330.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2791)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 189, 272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 552)
[M::mem_pestat] mean and std.dev: (210.18, 101.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 692)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (406, 851, 2227)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5869)
[M::mem_pestat] mean and std.dev: (1418.65, 1248.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7690)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (274, 626, 1396)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3640)
[M::mem_pestat] mean and std.dev: (815.94, 722.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4762)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724666 sequences (100000151 bp) in 3.335 CPU sec, 4.007 real sec...
sorting block 51, #reads = 1096695 mem = 536878403 peak = 1008746496
[M::mem_process_seqs] Processed 725790 reads in 215.334 CPU sec, 7.070 real sec
[M::mem_process_seqs] Processed 725384 reads in 150.830 CPU sec, 5.002 real sec
[M::process] read 725114 sequences (100000077 bp) in 3.596 CPU sec, 4.030 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 297944, 36, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 474, 925)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2297)
[M::mem_pestat] mean and std.dev: (556.81, 443.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2983)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 556)
[M::mem_pestat] mean and std.dev: (211.29, 101.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 697)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (312, 771, 1264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3168)
[M::mem_pestat] mean and std.dev: (704.27, 588.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4120)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 330, 860)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2214)
[M::mem_pestat] mean and std.dev: (476.76, 447.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2891)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724666 reads in 124.174 CPU sec, 4.195 real sec
sorting block 52, #reads = 1094043 mem = 536878446 peak = 1008746496
[M::process] read 724542 sequences (100000205 bp) in 2.978 CPU sec, 3.237 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 298077, 57, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (266, 410, 797)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1859)
[M::mem_pestat] mean and std.dev: (574.90, 478.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2489)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 189, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 558)
[M::mem_pestat] mean and std.dev: (211.42, 102.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 700)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (270, 550, 927)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2241)
[M::mem_pestat] mean and std.dev: (603.72, 465.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2898)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 447, 842)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2044)
[M::mem_pestat] mean and std.dev: (464.19, 318.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2645)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 53, #reads = 1094432 mem = 536878162 peak = 1021157376
[M::process] read 724130 sequences (100000043 bp) in 2.895 CPU sec, 3.287 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 297733, 36, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 311, 654)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1614)
[M::mem_pestat] mean and std.dev: (369.50, 306.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2094)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 559)
[M::mem_pestat] mean and std.dev: (211.87, 102.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 701)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (459, 1451, 3278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8916)
[M::mem_pestat] mean and std.dev: (1771.82, 2026.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11735)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (287, 518, 1110)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2756)
[M::mem_pestat] mean and std.dev: (673.14, 567.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3579)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 725114 reads in 246.474 CPU sec, 8.256 real sec
[M::mem_process_seqs] Processed 724542 reads in 153.895 CPU sec, 5.188 real sec
[M::process] read 724228 sequences (100000291 bp) in 3.046 CPU sec, 3.286 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 297280, 47, 81)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 235, 540)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1298)
[M::mem_pestat] mean and std.dev: (286.08, 237.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1677)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 559)
[M::mem_pestat] mean and std.dev: (212.30, 102.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 701)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 478, 1505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4075)
[M::mem_pestat] mean and std.dev: (807.89, 709.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5360)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 325, 1397)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3753)
[M::mem_pestat] mean and std.dev: (671.62, 741.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4931)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 54, #reads = 1094255 mem = 536881855 peak = 1021157376
[M::process] read 723888 sequences (100000053 bp) in 3.686 CPU sec, 4.095 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 297785, 40, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 506, 826)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2010)
[M::mem_pestat] mean and std.dev: (566.47, 438.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2602)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 190, 276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 560)
[M::mem_pestat] mean and std.dev: (212.79, 103.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 702)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 295, 969)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2585)
[M::mem_pestat] mean and std.dev: (508.87, 478.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3393)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 341, 752)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1920)
[M::mem_pestat] mean and std.dev: (430.98, 347.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2504)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724130 reads in 213.321 CPU sec, 7.005 real sec
[M::mem_process_seqs] Processed 724228 reads in 150.077 CPU sec, 4.912 real sec
sorting block 55, #reads = 1094752 mem = 536883709 peak = 1021157376
[M::process] read 723440 sequences (100000194 bp) in 3.534 CPU sec, 3.889 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 297312, 42, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (252, 360, 1174)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3018)
[M::mem_pestat] mean and std.dev: (615.89, 561.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3940)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 191, 277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 563)
[M::mem_pestat] mean and std.dev: (213.34, 103.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 706)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 480, 512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1238)
[M::mem_pestat] mean and std.dev: (365.76, 245.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1601)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 483, 1100)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2868)
[M::mem_pestat] mean and std.dev: (718.47, 664.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3752)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 296429, 29, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 401, 1520)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4252)
[M::mem_pestat] mean and std.dev: (827.92, 917.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5618)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 191, 277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 563)
[M::mem_pestat] mean and std.dev: (213.52, 103.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 706)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (117, 533, 1376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3894)
[M::mem_pestat] mean and std.dev: (737.39, 846.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5153)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 342, 1332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3570)
[M::mem_pestat] mean and std.dev: (644.00, 680.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4689)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723958 sequences (100000095 bp) in 3.423 CPU sec, 4.095 real sec...
[M::mem_process_seqs] Processed 723888 reads in 216.478 CPU sec, 7.106 real sec
[M::mem_process_seqs] Processed 723440 reads in 153.363 CPU sec, 5.033 real sec
sorting block 56, #reads = 1095027 mem = 536880776 peak = 1021157376
[M::process] read 723108 sequences (100000121 bp) in 3.379 CPU sec, 3.850 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (88, 296872, 43, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (267, 657, 1472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3882)
[M::mem_pestat] mean and std.dev: (788.56, 656.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5087)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 556)
[M::mem_pestat] mean and std.dev: (211.71, 101.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 697)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 655, 1104)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3022)
[M::mem_pestat] mean and std.dev: (730.05, 687.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3981)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 525, 1775)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4841)
[M::mem_pestat] mean and std.dev: (1080.53, 1143.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6374)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723958 reads in 124.686 CPU sec, 4.376 real sec
sorting block 57, #reads = 1093481 mem = 536881701 peak = 1021157376
[M::process] read 723336 sequences (100000122 bp) in 3.105 CPU sec, 3.535 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 296769, 39, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 373, 881)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2269)
[M::mem_pestat] mean and std.dev: (640.81, 695.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3424)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 191, 275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 557)
[M::mem_pestat] mean and std.dev: (212.20, 101.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 698)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (253, 852, 1431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3787)
[M::mem_pestat] mean and std.dev: (850.11, 717.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4965)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 499, 1500)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4094)
[M::mem_pestat] mean and std.dev: (725.29, 736.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5391)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723332 sequences (100000223 bp) in 3.157 CPU sec, 3.705 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 297224, 50, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 451, 1388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3724)
[M::mem_pestat] mean and std.dev: (722.69, 779.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4892)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 190, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 554)
[M::mem_pestat] mean and std.dev: (211.97, 101.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 694)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 823, 1307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3609)
[M::mem_pestat] mean and std.dev: (732.96, 619.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4760)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 322, 884)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2328)
[M::mem_pestat] mean and std.dev: (445.04, 434.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3050)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723108 reads in 249.396 CPU sec, 8.372 real sec
[M::mem_process_seqs] Processed 723336 reads in 152.873 CPU sec, 5.096 real sec
sorting block 58, #reads = 1093544 mem = 536879822 peak = 1021157376
[M::process] read 723586 sequences (100000253 bp) in 3.591 CPU sec, 4.111 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 296709, 46, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 408, 1029)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2685)
[M::mem_pestat] mean and std.dev: (642.09, 675.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3513)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 190, 273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 551)
[M::mem_pestat] mean and std.dev: (211.26, 101.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 690)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (276, 512, 1298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3342)
[M::mem_pestat] mean and std.dev: (726.18, 677.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4364)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 257, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (246.42, 94.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 297163, 52, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 389, 1600)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4366)
[M::mem_pestat] mean and std.dev: (806.43, 829.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5749)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 190, 273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 551)
[M::mem_pestat] mean and std.dev: (211.15, 101.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 690)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (545, 921, 1334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2912)
[M::mem_pestat] mean and std.dev: (920.96, 645.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3701)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 307, 1031)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2723)
[M::mem_pestat] mean and std.dev: (582.32, 638.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3569)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 59, #reads = 1093444 mem = 536879942 peak = 1021157376
[M::process] read 723276 sequences (100000198 bp) in 3.423 CPU sec, 4.028 real sec...
[M::mem_process_seqs] Processed 723332 reads in 227.316 CPU sec, 7.508 real sec
[M::mem_process_seqs] Processed 723586 reads in 150.329 CPU sec, 4.979 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 297078, 32, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 527, 1888)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5178)
[M::mem_pestat] mean and std.dev: (813.26, 805.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6823)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 190, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 554)
[M::mem_pestat] mean and std.dev: (211.81, 101.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 694)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (117, 320, 1338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3780)
[M::mem_pestat] mean and std.dev: (571.00, 645.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5001)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 375, 1054)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2798)
[M::mem_pestat] mean and std.dev: (519.60, 579.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3670)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723684 sequences (100000173 bp) in 3.831 CPU sec, 4.361 real sec...
[M::mem_process_seqs] Processed 723276 reads in 123.430 CPU sec, 4.192 real sec
sorting block 60, #reads = 1093652 mem = 536878159 peak = 1021157376
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 296878, 36, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 371, 1096)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2884)
[M::mem_pestat] mean and std.dev: (609.24, 665.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3778)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 553)
[M::mem_pestat] mean and std.dev: (211.04, 101.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 693)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 504, 748)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1932)
[M::mem_pestat] mean and std.dev: (414.16, 302.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2524)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 384, 1173)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3083)
[M::mem_pestat] mean and std.dev: (652.02, 593.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4038)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723096 sequences (100000000 bp) in 3.667 CPU sec, 4.031 real sec...
[M::mem_process_seqs] Processed 723684 reads in 124.748 CPU sec, 4.255 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 296827, 63, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 264, 902)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2366)
[M::mem_pestat] mean and std.dev: (497.16, 506.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3098)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 190, 275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 557)
[M::mem_pestat] mean and std.dev: (211.99, 101.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 698)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (405, 943, 1453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3549)
[M::mem_pestat] mean and std.dev: (937.45, 773.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4597)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 524, 1160)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2970)
[M::mem_pestat] mean and std.dev: (679.69, 541.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3875)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 61, #reads = 1092913 mem = 536885553 peak = 1021157376
[M::process] read 723118 sequences (100000201 bp) in 3.427 CPU sec, 4.006 real sec...
[M::mem_process_seqs] Processed 723096 reads in 123.188 CPU sec, 4.309 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (83, 296482, 33, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 273, 826)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2076)
[M::mem_pestat] mean and std.dev: (362.33, 305.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2701)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 191, 275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 557)
[M::mem_pestat] mean and std.dev: (212.23, 102.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 698)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 393, 865)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2137)
[M::mem_pestat] mean and std.dev: (510.37, 475.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2773)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 591, 1226)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3330)
[M::mem_pestat] mean and std.dev: (726.52, 619.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4382)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722700 sequences (100000148 bp) in 3.697 CPU sec, 4.064 real sec...
[M::mem_process_seqs] Processed 723118 reads in 121.783 CPU sec, 4.386 real sec
sorting block 62, #reads = 1092467 mem = 536878743 peak = 1021157376
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 296721, 57, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (263, 605, 1049)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2621)
[M::mem_pestat] mean and std.dev: (736.38, 586.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3407)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 191, 275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 557)
[M::mem_pestat] mean and std.dev: (212.38, 101.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 698)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 447, 1015)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2607)
[M::mem_pestat] mean and std.dev: (715.05, 761.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3761)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (276, 579, 955)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2313)
[M::mem_pestat] mean and std.dev: (551.18, 427.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2992)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722374 sequences (100000069 bp) in 3.306 CPU sec, 3.655 real sec...
[M::mem_process_seqs] Processed 722700 reads in 121.827 CPU sec, 4.349 real sec
sorting block 63, #reads = 1093654 mem = 536881560 peak = 1021157376
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 296396, 42, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 422, 1279)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3449)
[M::mem_pestat] mean and std.dev: (676.78, 697.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4534)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 191, 275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 557)
[M::mem_pestat] mean and std.dev: (212.61, 101.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 698)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 749, 1306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3570)
[M::mem_pestat] mean and std.dev: (629.91, 678.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4702)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 310, 703)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1757)
[M::mem_pestat] mean and std.dev: (411.50, 356.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2284)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722368 sequences (100000054 bp) in 3.747 CPU sec, 4.128 real sec...
[M::mem_process_seqs] Processed 722374 reads in 124.477 CPU sec, 4.260 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 296818, 33, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 280, 1235)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3421)
[M::mem_pestat] mean and std.dev: (483.37, 509.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4514)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 191, 275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 555)
[M::mem_pestat] mean and std.dev: (212.53, 101.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 695)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (76, 287, 1493)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4327)
[M::mem_pestat] mean and std.dev: (639.55, 736.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5744)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 368, 945)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2421)
[M::mem_pestat] mean and std.dev: (482.64, 418.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3159)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722824 sequences (100000275 bp) in 3.069 CPU sec, 3.585 real sec...
[M::mem_process_seqs] Processed 722368 reads in 121.169 CPU sec, 4.200 real sec
sorting block 64, #reads = 1093399 mem = 536881432 peak = 1021157376
[M::process] read 722456 sequences (100000212 bp) in 3.219 CPU sec, 3.597 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 296546, 46, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 529, 1453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4033)
[M::mem_pestat] mean and std.dev: (869.12, 1074.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5323)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 191, 275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 557)
[M::mem_pestat] mean and std.dev: (212.80, 102.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 698)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 792, 1838)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5138)
[M::mem_pestat] mean and std.dev: (1070.43, 1154.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6788)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (278, 487, 1111)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2777)
[M::mem_pestat] mean and std.dev: (645.85, 539.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3610)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 722824 reads in 124.436 CPU sec, 4.205 real sec
[M::process] read 721456 sequences (100000238 bp) in 3.255 CPU sec, 3.607 real sec...
sorting block 65, #reads = 1093815 mem = 536892087 peak = 1021157376
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 296622, 47, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 492, 723)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1679)
[M::mem_pestat] mean and std.dev: (513.56, 359.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2157)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 192, 277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 563)
[M::mem_pestat] mean and std.dev: (213.81, 103.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 706)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (272, 1125, 3771)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10769)
[M::mem_pestat] mean and std.dev: (2080.96, 2283.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14268)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 554, 1452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3900)
[M::mem_pestat] mean and std.dev: (674.26, 681.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5124)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 296617, 19, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 372, 937)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2401)
[M::mem_pestat] mean and std.dev: (482.05, 458.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3133)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 192, 278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 564)
[M::mem_pestat] mean and std.dev: (214.61, 103.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 707)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (118, 504, 1886)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5422)
[M::mem_pestat] mean and std.dev: (755.47, 962.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7190)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 326, 683)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1657)
[M::mem_pestat] mean and std.dev: (433.63, 374.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2144)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721470 sequences (100000049 bp) in 3.529 CPU sec, 4.163 real sec...
[M::mem_process_seqs] Processed 722456 reads in 253.169 CPU sec, 8.507 real sec
[M::mem_process_seqs] Processed 721456 reads in 153.192 CPU sec, 5.101 real sec
sorting block 66, #reads = 1092484 mem = 536881016 peak = 1021157376
[M::process] read 720792 sequences (100000086 bp) in 2.837 CPU sec, 3.046 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 296155, 42, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (257, 426, 845)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2021)
[M::mem_pestat] mean and std.dev: (562.73, 423.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2609)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 193, 279)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 567)
[M::mem_pestat] mean and std.dev: (214.90, 103.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 711)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 552, 1413)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3853)
[M::mem_pestat] mean and std.dev: (831.17, 871.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5073)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (272, 474, 912)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2192)
[M::mem_pestat] mean and std.dev: (588.68, 466.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2832)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 67, #reads = 1093028 mem = 536882880 peak = 1034948608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 296688, 28, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 412, 962)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2456)
[M::mem_pestat] mean and std.dev: (528.91, 406.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3203)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 194, 280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 568)
[M::mem_pestat] mean and std.dev: (215.71, 103.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 712)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (391, 924, 1627)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4099)
[M::mem_pestat] mean and std.dev: (1034.58, 874.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5335)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 532, 1559)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4243)
[M::mem_pestat] mean and std.dev: (607.48, 651.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5585)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720060 sequences (100000096 bp) in 3.501 CPU sec, 4.030 real sec...
[M::mem_process_seqs] Processed 721470 reads in 214.256 CPU sec, 7.055 real sec
[M::mem_process_seqs] Processed 720792 reads in 152.773 CPU sec, 5.067 real sec
[M::process] read 720218 sequences (100000288 bp) in 3.527 CPU sec, 3.977 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 296174, 43, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 395, 861)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2211)
[M::mem_pestat] mean and std.dev: (533.81, 494.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2886)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 195, 282)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 572)
[M::mem_pestat] mean and std.dev: (217.10, 104.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 717)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (62, 169, 728)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2060)
[M::mem_pestat] mean and std.dev: (391.60, 427.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2726)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 391, 807)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1983)
[M::mem_pestat] mean and std.dev: (486.61, 408.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2571)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 68, #reads = 1094067 mem = 536878271 peak = 1034948608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 296450, 32, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 543, 1671)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4615)
[M::mem_pestat] mean and std.dev: (1058.44, 1156.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6087)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 195, 283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 577)
[M::mem_pestat] mean and std.dev: (217.58, 105.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 724)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 461, 955)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2549)
[M::mem_pestat] mean and std.dev: (607.13, 541.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3346)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 381, 657)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1471)
[M::mem_pestat] mean and std.dev: (482.70, 351.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1891)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727852 sequences (100000031 bp) in 3.338 CPU sec, 3.819 real sec...
[M::mem_process_seqs] Processed 720060 reads in 219.738 CPU sec, 7.251 real sec
[M::mem_process_seqs] Processed 720218 reads in 151.639 CPU sec, 5.037 real sec
sorting block 69, #reads = 1092341 mem = 536883613 peak = 1034948608
[M::process] read 731428 sequences (100000288 bp) in 3.250 CPU sec, 3.564 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 298216, 42, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 250, 863)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2213)
[M::mem_pestat] mean and std.dev: (397.54, 356.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2888)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 185, 266)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 536)
[M::mem_pestat] mean and std.dev: (205.94, 98.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 671)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 364, 836)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2150)
[M::mem_pestat] mean and std.dev: (446.21, 390.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2807)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 258, 585)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1445)
[M::mem_pestat] mean and std.dev: (338.00, 277.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1875)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 299444, 36, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 303, 749)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1861)
[M::mem_pestat] mean and std.dev: (402.25, 285.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2417)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 180, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 521)
[M::mem_pestat] mean and std.dev: (200.92, 95.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 652)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (257, 716, 1178)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3020)
[M::mem_pestat] mean and std.dev: (651.43, 505.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3941)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 377, 783)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1865)
[M::mem_pestat] mean and std.dev: (464.45, 380.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2406)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 730290 sequences (100000141 bp) in 3.339 CPU sec, 3.882 real sec...
[M::mem_process_seqs] Processed 727852 reads in 221.305 CPU sec, 7.208 real sec
[M::mem_process_seqs] Processed 731428 reads in 153.596 CPU sec, 4.971 real sec
sorting block 70, #reads = 1091593 mem = 536877130 peak = 1034948608
[M::process] read 729474 sequences (100000048 bp) in 3.552 CPU sec, 3.880 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 299682, 50, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 371, 2872)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8262)
[M::mem_pestat] mean and std.dev: (1005.06, 1186.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10957)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 182, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 525)
[M::mem_pestat] mean and std.dev: (202.41, 96.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 657)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 360, 930)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2376)
[M::mem_pestat] mean and std.dev: (566.52, 466.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3099)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (285, 646, 1160)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2910)
[M::mem_pestat] mean and std.dev: (706.00, 501.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3785)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 730290 reads in 122.564 CPU sec, 4.187 real sec
[M::process] read 728592 sequences (100000156 bp) in 3.408 CPU sec, 4.014 real sec...
sorting block 71, #reads = 1098506 mem = 536881892 peak = 1034948608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 298857, 50, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 482, 1399)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3835)
[M::mem_pestat] mean and std.dev: (820.98, 875.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5053)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 183, 262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 528)
[M::mem_pestat] mean and std.dev: (203.34, 97.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 661)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 660, 931)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2355)
[M::mem_pestat] mean and std.dev: (641.64, 557.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3067)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 361, 1083)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2853)
[M::mem_pestat] mean and std.dev: (655.67, 745.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3738)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 729474 reads in 152.355 CPU sec, 5.217 real sec
[M::process] read 728626 sequences (100000157 bp) in 3.210 CPU sec, 3.627 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 299048, 46, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (285, 423, 1493)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3909)
[M::mem_pestat] mean and std.dev: (833.11, 861.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5117)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 184, 264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 532)
[M::mem_pestat] mean and std.dev: (204.59, 97.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 666)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 513, 1466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4070)
[M::mem_pestat] mean and std.dev: (894.43, 993.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5372)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 359, 1275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3395)
[M::mem_pestat] mean and std.dev: (567.61, 551.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4455)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 72, #reads = 1098322 mem = 536885448 peak = 1034948608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 298768, 43, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (246, 455, 859)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2085)
[M::mem_pestat] mean and std.dev: (533.17, 395.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2698)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 184, 265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 535)
[M::mem_pestat] mean and std.dev: (204.93, 98.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 670)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 570, 1542)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4352)
[M::mem_pestat] mean and std.dev: (649.56, 852.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5757)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 410, 1002)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2498)
[M::mem_pestat] mean and std.dev: (685.87, 626.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3246)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728098 sequences (100000202 bp) in 3.333 CPU sec, 3.730 real sec...
[M::mem_process_seqs] Processed 728592 reads in 244.212 CPU sec, 8.032 real sec
[M::mem_process_seqs] Processed 728626 reads in 150.305 CPU sec, 4.843 real sec
sorting block 73, #reads = 1097695 mem = 536880241 peak = 1034948608
[M::process] read 727990 sequences (100000265 bp) in 3.556 CPU sec, 3.882 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 298601, 36, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 399, 1521)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4177)
[M::mem_pestat] mean and std.dev: (702.08, 727.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5505)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 185, 267)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 541)
[M::mem_pestat] mean and std.dev: (206.26, 99.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 678)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (128, 279, 930)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2534)
[M::mem_pestat] mean and std.dev: (495.51, 539.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3336)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 386, 922)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2374)
[M::mem_pestat] mean and std.dev: (562.42, 482.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3100)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 298977, 34, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 521, 1066)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2832)
[M::mem_pestat] mean and std.dev: (710.35, 651.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3715)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 184, 266)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 538)
[M::mem_pestat] mean and std.dev: (206.12, 99.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 674)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (462, 672, 1799)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4473)
[M::mem_pestat] mean and std.dev: (968.81, 954.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5810)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (273, 830, 1595)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4239)
[M::mem_pestat] mean and std.dev: (859.98, 661.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5561)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727032 sequences (100000085 bp) in 2.744 CPU sec, 3.142 real sec...
[M::mem_process_seqs] Processed 728098 reads in 216.170 CPU sec, 7.134 real sec
[M::mem_process_seqs] Processed 727990 reads in 149.485 CPU sec, 4.938 real sec
sorting block 74, #reads = 1097733 mem = 536877817 peak = 1034948608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 298524, 36, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 546, 943)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2385)
[M::mem_pestat] mean and std.dev: (630.21, 526.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3106)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 186, 269)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 545)
[M::mem_pestat] mean and std.dev: (207.97, 100.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 683)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 621, 1854)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5096)
[M::mem_pestat] mean and std.dev: (949.16, 1051.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6717)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 486, 1148)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3012)
[M::mem_pestat] mean and std.dev: (627.43, 638.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3944)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726156 sequences (100000013 bp) in 4.003 CPU sec, 4.524 real sec...
[M::mem_process_seqs] Processed 727032 reads in 124.418 CPU sec, 4.187 real sec
sorting block 75, #reads = 1097093 mem = 536879373 peak = 1034948608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 298249, 35, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 338, 1293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3477)
[M::mem_pestat] mean and std.dev: (626.47, 730.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4569)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 187, 270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 546)
[M::mem_pestat] mean and std.dev: (208.49, 100.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 684)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 503, 4611)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13559)
[M::mem_pestat] mean and std.dev: (1775.54, 2322.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 18033)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 434, 978)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2456)
[M::mem_pestat] mean and std.dev: (599.07, 468.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3195)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726038 sequences (100000111 bp) in 3.489 CPU sec, 3.842 real sec...
[M::process] read 725420 sequences (100000140 bp) in 3.087 CPU sec, 3.508 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 298522, 56, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 391, 998)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2520)
[M::mem_pestat] mean and std.dev: (501.90, 468.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3281)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 187, 271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 549)
[M::mem_pestat] mean and std.dev: (209.12, 101.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 688)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (273, 684, 1614)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4296)
[M::mem_pestat] mean and std.dev: (1009.79, 1040.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5637)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 316, 789)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1955)
[M::mem_pestat] mean and std.dev: (427.91, 329.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2538)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 726038 reads in 119.793 CPU sec, 4.023 real sec
sorting block 76, #reads = 1097020 mem = 536886677 peak = 1034948608
[M::process] read 727226 sequences (100000019 bp) in 3.129 CPU sec, 3.301 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 297859, 38, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 536, 1652)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4522)
[M::mem_pestat] mean and std.dev: (806.36, 838.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5957)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 188, 272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 552)
[M::mem_pestat] mean and std.dev: (209.87, 101.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 692)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 380, 1016)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2762)
[M::mem_pestat] mean and std.dev: (572.64, 610.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3635)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 430, 1262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3414)
[M::mem_pestat] mean and std.dev: (873.02, 989.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4832)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 726156 reads in 338.940 CPU sec, 11.394 real sec
[M::mem_process_seqs] Processed 725420 reads in 152.849 CPU sec, 5.147 real sec
sorting block 77, #reads = 1095507 mem = 536881038 peak = 1047678976
[M::process] read 724940 sequences (100000279 bp) in 2.875 CPU sec, 3.508 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 298938, 25, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (330, 456, 1455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3705)
[M::mem_pestat] mean and std.dev: (808.27, 828.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4830)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 185, 267)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 539)
[M::mem_pestat] mean and std.dev: (206.72, 99.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 675)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 497, 2158)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6066)
[M::mem_pestat] mean and std.dev: (1208.36, 1399.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8020)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (283, 526, 1162)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2920)
[M::mem_pestat] mean and std.dev: (595.97, 481.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3799)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 297769, 38, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (290, 455, 890)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2090)
[M::mem_pestat] mean and std.dev: (560.87, 477.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2690)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 189, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 556)
[M::mem_pestat] mean and std.dev: (211.32, 102.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 697)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (262, 576, 1083)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2725)
[M::mem_pestat] mean and std.dev: (638.57, 464.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3546)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 411, 960)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2486)
[M::mem_pestat] mean and std.dev: (529.24, 473.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3249)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724684 sequences (100000047 bp) in 3.456 CPU sec, 3.978 real sec...
[M::mem_process_seqs] Processed 727226 reads in 253.933 CPU sec, 8.470 real sec
[M::mem_process_seqs] Processed 724940 reads in 150.990 CPU sec, 4.967 real sec
sorting block 78, #reads = 1095670 mem = 536879428 peak = 1047678976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 297785, 32, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 298, 395)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 819)
[M::mem_pestat] mean and std.dev: (276.38, 129.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1031)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 189, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 556)
[M::mem_pestat] mean and std.dev: (211.33, 102.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 697)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 779, 1225)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3215)
[M::mem_pestat] mean and std.dev: (711.89, 546.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4210)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 380, 1698)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4648)
[M::mem_pestat] mean and std.dev: (874.08, 874.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6123)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724822 sequences (100000236 bp) in 4.042 CPU sec, 4.515 real sec...
[M::mem_process_seqs] Processed 724684 reads in 121.418 CPU sec, 4.154 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (81, 297537, 27, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (262, 650, 1138)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2890)
[M::mem_pestat] mean and std.dev: (702.26, 571.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3766)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 189, 273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 553)
[M::mem_pestat] mean and std.dev: (210.79, 102.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 693)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (106, 475, 901)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2491)
[M::mem_pestat] mean and std.dev: (545.44, 528.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3286)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 583, 1382)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3652)
[M::mem_pestat] mean and std.dev: (757.48, 611.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4787)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 79, #reads = 1096186 mem = 536879233 peak = 1047678976
[M::process] read 724546 sequences (100000104 bp) in 3.059 CPU sec, 3.440 real sec...
[M::mem_process_seqs] Processed 724822 reads in 122.535 CPU sec, 4.190 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 297725, 46, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 335, 1155)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3093)
[M::mem_pestat] mean and std.dev: (611.10, 581.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4062)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 189, 273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 553)
[M::mem_pestat] mean and std.dev: (210.90, 101.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 693)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 582, 1409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3843)
[M::mem_pestat] mean and std.dev: (852.98, 906.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5060)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (313, 809, 1590)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4144)
[M::mem_pestat] mean and std.dev: (1031.86, 909.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5421)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723772 sequences (100000260 bp) in 3.363 CPU sec, 3.739 real sec...
[M::mem_process_seqs] Processed 724546 reads in 122.178 CPU sec, 4.127 real sec
sorting block 80, #reads = 1094648 mem = 536879336 peak = 1047678976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 297413, 40, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 405, 810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1964)
[M::mem_pestat] mean and std.dev: (462.15, 340.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2541)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 556)
[M::mem_pestat] mean and std.dev: (211.78, 102.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 697)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (107, 471, 1512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4322)
[M::mem_pestat] mean and std.dev: (669.95, 666.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5727)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 456, 1292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3496)
[M::mem_pestat] mean and std.dev: (582.55, 693.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4598)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723510 sequences (100000213 bp) in 3.144 CPU sec, 3.670 real sec...
[M::mem_process_seqs] Processed 723772 reads in 119.541 CPU sec, 4.136 real sec
sorting block 81, #reads = 1095285 mem = 536879165 peak = 1047678976
[M::process] read 723272 sequences (100000171 bp) in 3.270 CPU sec, 3.543 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 297047, 41, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 340, 914)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2308)
[M::mem_pestat] mean and std.dev: (572.48, 592.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3005)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 190, 275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 557)
[M::mem_pestat] mean and std.dev: (212.11, 102.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 698)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 307, 1841)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5145)
[M::mem_pestat] mean and std.dev: (791.33, 1042.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6797)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 361, 728)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1798)
[M::mem_pestat] mean and std.dev: (464.31, 385.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2333)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723510 reads in 124.525 CPU sec, 4.153 real sec
[M::process] read 723478 sequences (100000257 bp) in 3.329 CPU sec, 3.771 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 296682, 35, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (263, 561, 1890)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5144)
[M::mem_pestat] mean and std.dev: (940.49, 1108.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6771)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 190, 273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 551)
[M::mem_pestat] mean and std.dev: (211.12, 100.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 690)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 572, 1480)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4114)
[M::mem_pestat] mean and std.dev: (1006.03, 1254.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6026)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 277, 1779)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4855)
[M::mem_pestat] mean and std.dev: (778.72, 942.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6393)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723272 reads in 152.766 CPU sec, 5.181 real sec
sorting block 82, #reads = 1094099 mem = 536878485 peak = 1047678976
[M::process] read 723730 sequences (100000105 bp) in 3.687 CPU sec, 4.004 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 297167, 53, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 394, 840)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2118)
[M::mem_pestat] mean and std.dev: (578.91, 487.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2757)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 190, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 554)
[M::mem_pestat] mean and std.dev: (211.35, 101.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 694)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 537, 1883)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5227)
[M::mem_pestat] mean and std.dev: (1119.56, 1295.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6899)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 541, 1276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3378)
[M::mem_pestat] mean and std.dev: (802.71, 740.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4429)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 83, #reads = 1093124 mem = 536879267 peak = 1047678976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 297008, 45, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 565, 1159)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3069)
[M::mem_pestat] mean and std.dev: (838.89, 824.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4137)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 553)
[M::mem_pestat] mean and std.dev: (211.23, 101.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 693)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 533, 1640)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4490)
[M::mem_pestat] mean and std.dev: (889.19, 965.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5915)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 391, 721)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1735)
[M::mem_pestat] mean and std.dev: (492.69, 387.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2242)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723448 sequences (100000059 bp) in 3.377 CPU sec, 3.602 real sec...
[M::mem_process_seqs] Processed 723478 reads in 240.081 CPU sec, 7.805 real sec
[M::mem_process_seqs] Processed 723730 reads in 140.539 CPU sec, 4.478 real sec
sorting block 84, #reads = 1093357 mem = 536879341 peak = 1047678976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 296781, 55, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 596, 888)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2270)
[M::mem_pestat] mean and std.dev: (538.07, 436.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2961)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 190, 273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 551)
[M::mem_pestat] mean and std.dev: (211.32, 101.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 690)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 512, 1178)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3062)
[M::mem_pestat] mean and std.dev: (742.52, 695.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4004)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 529, 1456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3876)
[M::mem_pestat] mean and std.dev: (867.22, 886.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5086)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722900 sequences (100000035 bp) in 3.968 CPU sec, 4.173 real sec...
[M::process] read 722704 sequences (100000116 bp) in 2.158 CPU sec, 2.174 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 297231, 46, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 299, 839)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2131)
[M::mem_pestat] mean and std.dev: (444.77, 372.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2777)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 191, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 554)
[M::mem_pestat] mean and std.dev: (212.12, 101.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 694)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 754, 1761)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4867)
[M::mem_pestat] mean and std.dev: (920.67, 842.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6420)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 455, 1008)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2650)
[M::mem_pestat] mean and std.dev: (628.75, 627.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3471)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 722900 reads in 115.394 CPU sec, 3.623 real sec
[M::process] read 722592 sequences (100000051 bp) in 2.246 CPU sec, 2.266 real sec...
sorting block 85, #reads = 1093330 mem = 536875777 peak = 1047678976
[M::mem_process_seqs] Processed 723448 reads in 287.441 CPU sec, 9.234 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 296592, 32, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 327, 1454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3958)
[M::mem_pestat] mean and std.dev: (777.65, 808.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5210)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 191, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 554)
[M::mem_pestat] mean and std.dev: (212.18, 101.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 694)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (79, 719, 2769)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8149)
[M::mem_pestat] mean and std.dev: (1354.32, 1803.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10839)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 381, 810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1936)
[M::mem_pestat] mean and std.dev: (417.88, 306.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2499)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 296085, 27, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 436, 780)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2008)
[M::mem_pestat] mean and std.dev: (437.22, 353.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2622)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 191, 275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 557)
[M::mem_pestat] mean and std.dev: (212.17, 101.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 698)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 394, 608)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1418)
[M::mem_pestat] mean and std.dev: (351.14, 215.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1823)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (284, 352, 1093)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2711)
[M::mem_pestat] mean and std.dev: (593.71, 455.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3520)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722446 sequences (100000013 bp) in 3.513 CPU sec, 4.580 real sec...
[M::mem_process_seqs] Processed 722704 reads in 242.089 CPU sec, 7.770 real sec
[M::mem_process_seqs] Processed 722592 reads in 151.451 CPU sec, 4.850 real sec
sorting block 86, #reads = 1093587 mem = 536885579 peak = 1047678976
[M::process] read 722152 sequences (100000259 bp) in 4.094 CPU sec, 4.424 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 297262, 62, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 368, 1042)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2626)
[M::mem_pestat] mean and std.dev: (519.00, 418.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3418)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 191, 276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 558)
[M::mem_pestat] mean and std.dev: (213.03, 102.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 699)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 730, 1965)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5399)
[M::mem_pestat] mean and std.dev: (1332.82, 1479.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7251)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 453, 1131)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2947)
[M::mem_pestat] mean and std.dev: (601.92, 633.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3855)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 722446 reads in 122.102 CPU sec, 4.072 real sec
sorting block 87, #reads = 1093218 mem = 536891127 peak = 1047678976
[M::process] read 722068 sequences (100000057 bp) in 3.456 CPU sec, 4.205 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 296609, 46, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 345, 1210)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3262)
[M::mem_pestat] mean and std.dev: (723.38, 690.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4288)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 192, 276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 558)
[M::mem_pestat] mean and std.dev: (213.29, 102.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 699)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (361, 679, 1150)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2728)
[M::mem_pestat] mean and std.dev: (758.89, 514.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3517)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 374, 768)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1976)
[M::mem_pestat] mean and std.dev: (526.55, 539.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2683)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 722152 reads in 151.346 CPU sec, 5.140 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 296912, 46, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 390, 1487)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4183)
[M::mem_pestat] mean and std.dev: (895.46, 1084.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5531)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
sorting block 88, #reads = 1093168 mem = 536882343 peak = 1047678976
[M::mem_pestat] (25, 50, 75) percentile: (135, 192, 276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 558)
[M::mem_pestat] mean and std.dev: (213.35, 102.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 699)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 601, 1291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3411)
[M::mem_pestat] mean and std.dev: (737.86, 626.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4471)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 355, 1020)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2656)
[M::mem_pestat] mean and std.dev: (624.86, 622.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3474)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721616 sequences (100000075 bp) in 3.895 CPU sec, 4.286 real sec...
[M::mem_process_seqs] Processed 722068 reads in 148.930 CPU sec, 4.997 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 296432, 35, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (301, 654, 1791)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4771)
[M::mem_pestat] mean and std.dev: (968.88, 988.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6261)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 193, 276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 558)
[M::mem_pestat] mean and std.dev: (213.52, 101.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 699)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (88, 404, 989)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2791)
[M::mem_pestat] mean and std.dev: (410.90, 421.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3692)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 342, 1095)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2897)
[M::mem_pestat] mean and std.dev: (626.53, 653.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3798)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721082 sequences (100000017 bp) in 3.545 CPU sec, 3.846 real sec...
[M::mem_process_seqs] Processed 721616 reads in 121.517 CPU sec, 4.011 real sec
sorting block 89, #reads = 1092418 mem = 536886147 peak = 1047678976
[M::process] read 720702 sequences (100000145 bp) in 3.167 CPU sec, 3.363 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 295985, 28, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 474, 1074)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2756)
[M::mem_pestat] mean and std.dev: (579.88, 505.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3597)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 194, 278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 562)
[M::mem_pestat] mean and std.dev: (214.66, 102.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 704)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (277, 642, 1148)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2890)
[M::mem_pestat] mean and std.dev: (681.52, 545.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3761)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (291, 672, 2057)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5589)
[M::mem_pestat] mean and std.dev: (1245.33, 1226.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7355)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720752 sequences (100000098 bp) in 2.126 CPU sec, 2.169 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 295994, 50, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 288, 1780)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4964)
[M::mem_pestat] mean and std.dev: (977.95, 1213.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6556)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 193, 278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 562)
[M::mem_pestat] mean and std.dev: (214.87, 102.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 704)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (130, 402, 755)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2005)
[M::mem_pestat] mean and std.dev: (432.11, 372.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2630)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 321, 838)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2074)
[M::mem_pestat] mean and std.dev: (489.48, 424.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2692)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 721082 reads in 197.381 CPU sec, 6.266 real sec
[M::process] read 720420 sequences (100000020 bp) in 1.707 CPU sec, 1.710 real sec...
sorting block 90, #reads = 1092482 mem = 536876593 peak = 1047678976
[M::mem_process_seqs] Processed 720702 reads in 137.446 CPU sec, 4.351 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 296211, 35, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 425, 730)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1844)
[M::mem_pestat] mean and std.dev: (490.21, 417.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2401)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 194, 280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 568)
[M::mem_pestat] mean and std.dev: (215.95, 103.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 712)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 344, 927)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2359)
[M::mem_pestat] mean and std.dev: (491.00, 468.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3075)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 319, 617)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1465)
[M::mem_pestat] mean and std.dev: (333.92, 238.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1889)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 91, #reads = 1091665 mem = 536881083 peak = 1047678976
[M::process] read 720736 sequences (100000043 bp) in 3.673 CPU sec, 3.902 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 296383, 45, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 447, 775)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1797)
[M::mem_pestat] mean and std.dev: (484.95, 368.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2308)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 195, 281)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 571)
[M::mem_pestat] mean and std.dev: (216.69, 104.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 716)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 606, 1296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3572)
[M::mem_pestat] mean and std.dev: (847.14, 793.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4710)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 386, 893)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2177)
[M::mem_pestat] mean and std.dev: (468.24, 283.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2819)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 720752 reads in 211.908 CPU sec, 6.786 real sec
[M::mem_process_seqs] Processed 720420 reads in 151.909 CPU sec, 4.826 real sec
[M::process] read 730286 sequences (100000164 bp) in 2.991 CPU sec, 3.086 real sec...
sorting block 92, #reads = 1091042 mem = 536881247 peak = 1047678976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 296587, 48, 98)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 283, 841)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2161)
[M::mem_pestat] mean and std.dev: (490.88, 450.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2821)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 194, 280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 568)
[M::mem_pestat] mean and std.dev: (216.26, 104.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 712)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (323, 672, 2087)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5615)
[M::mem_pestat] mean and std.dev: (1099.35, 1040.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7379)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 370, 927)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2347)
[M::mem_pestat] mean and std.dev: (455.62, 388.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3057)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 735790 sequences (100000289 bp) in 2.871 CPU sec, 3.077 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 299294, 39, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 323, 1175)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3053)
[M::mem_pestat] mean and std.dev: (549.64, 515.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3992)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 182, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 525)
[M::mem_pestat] mean and std.dev: (202.29, 96.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 657)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (468, 824, 2161)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5547)
[M::mem_pestat] mean and std.dev: (1176.20, 1118.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7240)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 635, 1534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4128)
[M::mem_pestat] mean and std.dev: (852.22, 745.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5425)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 734372 sequences (100000217 bp) in 1.700 CPU sec, 1.696 real sec...
[M::mem_process_seqs] Processed 720736 reads in 203.497 CPU sec, 6.490 real sec
sorting block 93, #reads = 1091061 mem = 536890684 peak = 1047678976
[M::mem_process_seqs] Processed 730286 reads in 149.631 CPU sec, 4.774 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 301989, 50, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 446, 788)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2002)
[M::mem_pestat] mean and std.dev: (545.25, 496.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2609)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (125, 175, 248)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 494)
[M::mem_pestat] mean and std.dev: (193.60, 90.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 617)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (275, 444, 1007)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2471)
[M::mem_pestat] mean and std.dev: (599.52, 441.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3203)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 411, 847)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2141)
[M::mem_pestat] mean and std.dev: (478.32, 427.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2788)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 733200 sequences (100000021 bp) in 2.841 CPU sec, 2.951 real sec...
[M::process] read 732004 sequences (100000097 bp) in 1.760 CPU sec, 1.756 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 301104, 45, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 371, 944)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2406)
[M::mem_pestat] mean and std.dev: (556.64, 479.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3137)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (126, 176, 251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 501)
[M::mem_pestat] mean and std.dev: (195.54, 92.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 626)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (105, 424, 862)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2376)
[M::mem_pestat] mean and std.dev: (428.71, 410.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3133)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (262, 352, 1741)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4699)
[M::mem_pestat] mean and std.dev: (1057.61, 1264.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6178)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 735790 reads in 192.279 CPU sec, 6.098 real sec
sorting block 94, #reads = 1093859 mem = 536879225 peak = 1047678976
[M::process] read 731298 sequences (100000250 bp) in 2.389 CPU sec, 2.393 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 301022, 32, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 279, 667)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1547)
[M::mem_pestat] mean and std.dev: (444.31, 357.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1987)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 178, 253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 505)
[M::mem_pestat] mean and std.dev: (197.42, 93.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 631)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 490, 1193)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3151)
[M::mem_pestat] mean and std.dev: (654.03, 595.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4130)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 376, 642)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1468)
[M::mem_pestat] mean and std.dev: (393.83, 253.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1881)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 733200 reads in 105.400 CPU sec, 3.606 real sec
sorting block 95, #reads = 1100130 mem = 536879585 peak = 1075654656
[M::mem_process_seqs] Processed 734372 reads in 257.293 CPU sec, 8.437 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 300490, 39, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 619, 1640)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4522)
[M::mem_pestat] mean and std.dev: (752.98, 789.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5963)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 179, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 512)
[M::mem_pestat] mean and std.dev: (198.81, 94.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 640)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 448, 1210)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3208)
[M::mem_pestat] mean and std.dev: (737.25, 818.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4207)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 299, 1051)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2721)
[M::mem_pestat] mean and std.dev: (490.87, 509.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3556)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 730318 sequences (100000046 bp) in 2.760 CPU sec, 2.825 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 300294, 29, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 297, 1221)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3365)
[M::mem_pestat] mean and std.dev: (508.91, 579.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4437)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 180, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 515)
[M::mem_pestat] mean and std.dev: (200.00, 95.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 644)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (372, 634, 2113)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5595)
[M::mem_pestat] mean and std.dev: (1175.34, 1121.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7336)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 492, 970)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2468)
[M::mem_pestat] mean and std.dev: (680.54, 599.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3217)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 730080 sequences (100000130 bp) in 2.320 CPU sec, 2.321 real sec...
[M::mem_process_seqs] Processed 732004 reads in 221.845 CPU sec, 7.065 real sec
sorting block 96, #reads = 1099580 mem = 536882165 peak = 1075654656
[M::mem_process_seqs] Processed 731298 reads in 140.412 CPU sec, 4.442 real sec
sorting block 97, #reads = 1099690 mem = 536878665 peak = 1106149376
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 300211, 50, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 311, 1046)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2752)
[M::mem_pestat] mean and std.dev: (579.37, 602.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3605)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 181, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 522)
[M::mem_pestat] mean and std.dev: (201.81, 96.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 653)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (386, 686, 903)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1937)
[M::mem_pestat] mean and std.dev: (567.64, 302.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2454)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 334, 970)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2510)
[M::mem_pestat] mean and std.dev: (427.83, 408.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3280)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 729456 sequences (100000161 bp) in 3.214 CPU sec, 3.356 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 300428, 38, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 411, 1319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3611)
[M::mem_pestat] mean and std.dev: (679.57, 709.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4757)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 182, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 525)
[M::mem_pestat] mean and std.dev: (202.75, 97.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 657)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (341, 738, 1522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3884)
[M::mem_pestat] mean and std.dev: (832.32, 704.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5065)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 261, 812)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2040)
[M::mem_pestat] mean and std.dev: (450.86, 451.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2654)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728548 sequences (100000158 bp) in 2.551 CPU sec, 2.572 real sec...
[M::mem_process_seqs] Processed 730318 reads in 210.359 CPU sec, 6.783 real sec
[M::mem_process_seqs] Processed 730080 reads in 143.827 CPU sec, 4.687 real sec
sorting block 98, #reads = 1097452 mem = 536884557 peak = 1106149376
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 299387, 46, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 435, 1096)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2814)
[M::mem_pestat] mean and std.dev: (618.18, 628.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3673)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 182, 262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 528)
[M::mem_pestat] mean and std.dev: (203.47, 97.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 661)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 619, 1684)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4730)
[M::mem_pestat] mean and std.dev: (831.55, 1043.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6253)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (323, 499, 1062)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2540)
[M::mem_pestat] mean and std.dev: (691.74, 558.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3279)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728218 sequences (100000100 bp) in 3.052 CPU sec, 3.162 real sec...
[M::process] read 727596 sequences (100000273 bp) in 2.380 CPU sec, 2.381 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 299760, 30, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 302, 567)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1303)
[M::mem_pestat] mean and std.dev: (343.40, 226.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1671)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 183, 264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 532)
[M::mem_pestat] mean and std.dev: (204.39, 98.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 666)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 514, 2881)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8279)
[M::mem_pestat] mean and std.dev: (1334.90, 1427.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10978)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 509, 1422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3886)
[M::mem_pestat] mean and std.dev: (657.49, 631.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5118)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 729456 reads in 222.772 CPU sec, 7.166 real sec
sorting block 99, #reads = 1094456 mem = 536885441 peak = 1106149376
[M::mem_process_seqs] Processed 728548 reads in 143.269 CPU sec, 4.677 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 298966, 42, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 285, 592)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1410)
[M::mem_pestat] mean and std.dev: (336.76, 267.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1819)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 184, 266)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 538)
[M::mem_pestat] mean and std.dev: (205.88, 99.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 674)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (276, 1483, 2717)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7599)
[M::mem_pestat] mean and std.dev: (1695.20, 1592.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10040)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 285, 552)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1286)
[M::mem_pestat] mean and std.dev: (332.38, 205.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1653)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727020 sequences (100000088 bp) in 3.380 CPU sec, 3.534 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 299110, 46, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 290, 1257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3409)
[M::mem_pestat] mean and std.dev: (695.88, 754.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4485)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 267)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 539)
[M::mem_pestat] mean and std.dev: (206.74, 100.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 675)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 717, 1275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3457)
[M::mem_pestat] mean and std.dev: (724.40, 623.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4548)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 464, 1307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3451)
[M::mem_pestat] mean and std.dev: (567.97, 532.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4523)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727078 sequences (100000129 bp) in 2.289 CPU sec, 2.292 real sec...
[M::mem_process_seqs] Processed 728218 reads in 210.985 CPU sec, 6.825 real sec
sorting block 100, #reads = 1095707 mem = 536882775 peak = 1106149376
[M::mem_process_seqs] Processed 727596 reads in 144.576 CPU sec, 4.718 real sec
sorting block 101, #reads = 1096799 mem = 536889736 peak = 1106149376
[M::process] read 726690 sequences (100000168 bp) in 2.937 CPU sec, 3.058 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 298573, 52, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 494, 1418)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3724)
[M::mem_pestat] mean and std.dev: (663.96, 517.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4877)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 185, 267)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 539)
[M::mem_pestat] mean and std.dev: (206.93, 100.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 675)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 567, 2018)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5716)
[M::mem_pestat] mean and std.dev: (1088.59, 1425.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7565)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 337, 1270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3402)
[M::mem_pestat] mean and std.dev: (766.96, 818.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4468)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725870 sequences (100000115 bp) in 2.250 CPU sec, 2.257 real sec...
[M::mem_process_seqs] Processed 727078 reads in 122.388 CPU sec, 3.889 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 298852, 62, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 379, 805)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1959)
[M::mem_pestat] mean and std.dev: (507.83, 405.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2536)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 185, 268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 542)
[M::mem_pestat] mean and std.dev: (207.35, 100.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 679)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 741, 1191)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3163)
[M::mem_pestat] mean and std.dev: (781.76, 631.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4149)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 432, 1211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3173)
[M::mem_pestat] mean and std.dev: (672.93, 731.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4154)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 298387, 48, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 444, 1388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3820)
[M::mem_pestat] mean and std.dev: (676.92, 740.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5036)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 186, 269)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 545)
[M::mem_pestat] mean and std.dev: (208.24, 101.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 683)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 564, 827)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2085)
[M::mem_pestat] mean and std.dev: (527.48, 424.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2714)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 457, 980)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2526)
[M::mem_pestat] mean and std.dev: (576.28, 521.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3299)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 727020 reads in 323.584 CPU sec, 10.387 real sec
[M::process] read 725280 sequences (100000245 bp) in 2.688 CPU sec, 2.696 real sec...
sorting block 102, #reads = 1094770 mem = 536879706 peak = 1106149376
[M::mem_process_seqs] Processed 726690 reads in 174.287 CPU sec, 5.822 real sec
sorting block 103, #reads = 1094663 mem = 536883677 peak = 1110777856
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 297969, 55, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 346, 1044)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2746)
[M::mem_pestat] mean and std.dev: (547.31, 505.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3597)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 187, 270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 546)
[M::mem_pestat] mean and std.dev: (208.84, 101.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 684)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 319, 1190)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3242)
[M::mem_pestat] mean and std.dev: (551.66, 635.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4268)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 315, 802)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2068)
[M::mem_pestat] mean and std.dev: (443.06, 407.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2701)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725186 sequences (100000243 bp) in 3.327 CPU sec, 3.499 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 297387, 28, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (273, 416, 913)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2193)
[M::mem_pestat] mean and std.dev: (566.69, 512.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2833)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 187, 271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 549)
[M::mem_pestat] mean and std.dev: (209.45, 101.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 688)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (308, 569, 1081)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2627)
[M::mem_pestat] mean and std.dev: (682.62, 519.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3400)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 387, 853)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2061)
[M::mem_pestat] mean and std.dev: (506.53, 437.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2665)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724618 sequences (100000067 bp) in 2.258 CPU sec, 2.258 real sec...
[M::mem_process_seqs] Processed 725870 reads in 214.675 CPU sec, 7.062 real sec
[M::mem_process_seqs] Processed 725280 reads in 149.448 CPU sec, 4.777 real sec
sorting block 104, #reads = 1092269 mem = 536878794 peak = 1110777856
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 297817, 42, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 340, 881)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2217)
[M::mem_pestat] mean and std.dev: (487.04, 410.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2885)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 187, 271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 549)
[M::mem_pestat] mean and std.dev: (209.60, 101.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 688)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (404, 814, 1435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3497)
[M::mem_pestat] mean and std.dev: (924.61, 723.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4528)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 319, 637)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1477)
[M::mem_pestat] mean and std.dev: (385.39, 247.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1897)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724308 sequences (100000163 bp) in 3.806 CPU sec, 4.058 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 297303, 41, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (266, 429, 1988)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5432)
[M::mem_pestat] mean and std.dev: (952.51, 1127.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7154)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 188, 271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 547)
[M::mem_pestat] mean and std.dev: (209.66, 101.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 685)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (113, 542, 1322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3740)
[M::mem_pestat] mean and std.dev: (754.00, 954.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4949)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 367, 818)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2082)
[M::mem_pestat] mean and std.dev: (466.67, 415.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2714)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 725186 reads in 210.311 CPU sec, 6.687 real sec
[M::process] read 724362 sequences (100000069 bp) in 2.742 CPU sec, 2.759 real sec...
[M::mem_process_seqs] Processed 724618 reads in 149.674 CPU sec, 4.932 real sec
sorting block 105, #reads = 1093102 mem = 536882182 peak = 1110777856
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 296717, 37, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (263, 457, 1425)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3749)
[M::mem_pestat] mean and std.dev: (761.31, 720.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4911)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 189, 273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 553)
[M::mem_pestat] mean and std.dev: (210.79, 101.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 693)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (292, 733, 2674)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7438)
[M::mem_pestat] mean and std.dev: (1228.94, 1316.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9820)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 502, 1231)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3187)
[M::mem_pestat] mean and std.dev: (733.77, 715.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4165)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724054 sequences (100000222 bp) in 2.947 CPU sec, 3.099 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 297007, 33, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 230, 850)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2182)
[M::mem_pestat] mean and std.dev: (449.74, 470.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2848)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 188, 271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 547)
[M::mem_pestat] mean and std.dev: (210.02, 101.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 685)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 951, 2020)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5740)
[M::mem_pestat] mean and std.dev: (908.77, 831.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7600)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 393, 778)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1888)
[M::mem_pestat] mean and std.dev: (464.50, 378.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2443)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724808 sequences (100000091 bp) in 2.523 CPU sec, 2.544 real sec...
[M::mem_process_seqs] Processed 724308 reads in 221.640 CPU sec, 7.273 real sec
sorting block 106, #reads = 1091669 mem = 536879816 peak = 1110777856
[M::mem_process_seqs] Processed 724362 reads in 151.664 CPU sec, 4.924 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (79, 297179, 46, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 536, 1003)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2547)
[M::mem_pestat] mean and std.dev: (632.03, 547.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3319)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 189, 272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 550)
[M::mem_pestat] mean and std.dev: (210.20, 101.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 689)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (310, 671, 1805)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4795)
[M::mem_pestat] mean and std.dev: (994.21, 1071.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6290)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (342, 1037, 2387)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6477)
[M::mem_pestat] mean and std.dev: (1458.32, 1418.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8522)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 107, #reads = 1092082 mem = 536878899 peak = 1110777856
[M::process] read 723854 sequences (100000172 bp) in 3.360 CPU sec, 3.519 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 297831, 55, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 443, 1216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3264)
[M::mem_pestat] mean and std.dev: (667.06, 651.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4288)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 188, 271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 547)
[M::mem_pestat] mean and std.dev: (209.54, 101.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 685)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (290, 505, 980)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2360)
[M::mem_pestat] mean and std.dev: (608.78, 558.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3050)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 434, 1369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3607)
[M::mem_pestat] mean and std.dev: (817.10, 840.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4726)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724054 reads in 216.851 CPU sec, 7.016 real sec
[M::process] read 723496 sequences (100000169 bp) in 2.624 CPU sec, 2.635 real sec...
[M::mem_process_seqs] Processed 724808 reads in 155.303 CPU sec, 5.177 real sec
sorting block 108, #reads = 1091221 mem = 536880561 peak = 1110777856
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 297093, 52, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 366, 1710)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4660)
[M::mem_pestat] mean and std.dev: (792.65, 912.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6135)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 189, 273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 553)
[M::mem_pestat] mean and std.dev: (211.47, 102.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 693)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (257, 534, 989)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2453)
[M::mem_pestat] mean and std.dev: (576.62, 441.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3185)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 386, 1177)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3021)
[M::mem_pestat] mean and std.dev: (562.92, 545.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3943)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723540 sequences (100000178 bp) in 3.344 CPU sec, 3.507 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 296652, 45, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 268, 1013)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2693)
[M::mem_pestat] mean and std.dev: (546.85, 658.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3533)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 190, 275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 557)
[M::mem_pestat] mean and std.dev: (212.55, 103.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 698)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 404, 1011)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2665)
[M::mem_pestat] mean and std.dev: (436.62, 366.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3492)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (288, 508, 1082)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2670)
[M::mem_pestat] mean and std.dev: (652.74, 523.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3464)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722972 sequences (100000060 bp) in 2.598 CPU sec, 2.603 real sec...
[M::mem_process_seqs] Processed 723854 reads in 224.781 CPU sec, 7.406 real sec
[M::mem_process_seqs] Processed 723496 reads in 155.038 CPU sec, 5.013 real sec
sorting block 109, #reads = 1090239 mem = 536886555 peak = 1110777856
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 297410, 48, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 319, 847)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2143)
[M::mem_pestat] mean and std.dev: (436.05, 369.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2791)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 553)
[M::mem_pestat] mean and std.dev: (211.12, 101.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 693)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 514, 1156)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3152)
[M::mem_pestat] mean and std.dev: (550.68, 554.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4150)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 333, 1083)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2827)
[M::mem_pestat] mean and std.dev: (478.14, 533.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3699)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723052 sequences (100000017 bp) in 3.552 CPU sec, 3.783 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 296930, 40, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 321, 888)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2322)
[M::mem_pestat] mean and std.dev: (483.60, 481.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3039)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 190, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 554)
[M::mem_pestat] mean and std.dev: (211.78, 101.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 694)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (332, 681, 1887)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4997)
[M::mem_pestat] mean and std.dev: (1090.18, 1175.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6552)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 322, 762)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1942)
[M::mem_pestat] mean and std.dev: (419.47, 363.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2532)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723540 reads in 225.178 CPU sec, 7.282 real sec
[M::process] read 722782 sequences (100000269 bp) in 2.561 CPU sec, 2.567 real sec...
sorting block 110, #reads = 1090895 mem = 536880502 peak = 1110777856
[M::mem_process_seqs] Processed 722972 reads in 158.253 CPU sec, 5.246 real sec
sorting block 111, #reads = 1091206 mem = 536884445 peak = 1110777856
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 296556, 50, 86)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 401, 810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2040)
[M::mem_pestat] mean and std.dev: (476.75, 351.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2655)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 190, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 554)
[M::mem_pestat] mean and std.dev: (211.82, 101.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 694)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (298, 606, 1170)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2914)
[M::mem_pestat] mean and std.dev: (718.84, 546.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3786)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 411, 880)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2224)
[M::mem_pestat] mean and std.dev: (508.87, 444.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2896)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723398 sequences (100000284 bp) in 3.419 CPU sec, 3.597 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 297022, 34, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 380, 1015)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2655)
[M::mem_pestat] mean and std.dev: (665.76, 639.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3475)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 191, 275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 557)
[M::mem_pestat] mean and std.dev: (212.12, 101.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 698)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (480, 852, 1520)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3600)
[M::mem_pestat] mean and std.dev: (875.50, 594.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4640)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (278, 389, 973)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2363)
[M::mem_pestat] mean and std.dev: (586.50, 532.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3058)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723296 sequences (100000058 bp) in 2.676 CPU sec, 2.689 real sec...
[M::mem_process_seqs] Processed 723052 reads in 229.190 CPU sec, 7.582 real sec
[M::mem_process_seqs] Processed 722782 reads in 158.595 CPU sec, 5.221 real sec
sorting block 112, #reads = 1090773 mem = 536877520 peak = 1110777856
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 297217, 34, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 389, 1224)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3242)
[M::mem_pestat] mean and std.dev: (717.32, 681.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4251)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 190, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 554)
[M::mem_pestat] mean and std.dev: (211.77, 101.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 694)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (311, 813, 1334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3380)
[M::mem_pestat] mean and std.dev: (910.72, 918.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4583)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 280, 807)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2073)
[M::mem_pestat] mean and std.dev: (420.38, 376.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2706)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723302 sequences (100000238 bp) in 3.413 CPU sec, 3.720 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 296950, 56, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (300, 588, 1376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3528)
[M::mem_pestat] mean and std.dev: (866.54, 741.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4604)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 190, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 554)
[M::mem_pestat] mean and std.dev: (211.62, 101.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 694)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 550, 1328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3508)
[M::mem_pestat] mean and std.dev: (799.33, 714.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4598)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (261, 442, 958)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2352)
[M::mem_pestat] mean and std.dev: (492.00, 315.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3049)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723398 reads in 227.363 CPU sec, 7.473 real sec
[M::mem_process_seqs] Processed 723296 reads in 161.428 CPU sec, 5.177 real sec
[M::process] read 724096 sequences (100000057 bp) in 3.583 CPU sec, 3.843 real sec...
sorting block 113, #reads = 1091064 mem = 536876771 peak = 1110777856
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 296726, 19, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 349, 666)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1596)
[M::mem_pestat] mean and std.dev: (384.13, 256.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2061)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 190, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 554)
[M::mem_pestat] mean and std.dev: (211.58, 101.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 694)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (261, 314, 1122)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2844)
[M::mem_pestat] mean and std.dev: (641.79, 625.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3705)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 391, 800)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1946)
[M::mem_pestat] mean and std.dev: (529.66, 412.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2519)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 737170 sequences (100000171 bp) in 3.198 CPU sec, 3.355 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 297024, 37, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 465, 914)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2404)
[M::mem_pestat] mean and std.dev: (483.42, 418.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3149)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 189, 272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 550)
[M::mem_pestat] mean and std.dev: (210.69, 101.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 689)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 508, 1511)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4085)
[M::mem_pestat] mean and std.dev: (763.29, 906.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5372)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 443, 1735)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4755)
[M::mem_pestat] mean and std.dev: (930.73, 1008.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6265)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723302 reads in 229.023 CPU sec, 7.367 real sec
sorting block 114, #reads = 1091963 mem = 536877054 peak = 1110777856
[M::mem_process_seqs] Processed 724096 reads in 162.724 CPU sec, 5.167 real sec
[M::process] read 737002 sequences (100000138 bp) in 3.019 CPU sec, 3.121 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 302079, 35, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 481, 1825)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5099)
[M::mem_pestat] mean and std.dev: (803.70, 970.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6736)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (125, 174, 246)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 488)
[M::mem_pestat] mean and std.dev: (191.81, 89.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 609)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 444, 1136)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3122)
[M::mem_pestat] mean and std.dev: (611.84, 629.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4115)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 398, 775)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1893)
[M::mem_pestat] mean and std.dev: (561.76, 476.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2469)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 115, #reads = 1089668 mem = 536883378 peak = 1137336320
[M::process] read 734766 sequences (100000161 bp) in 3.437 CPU sec, 4.082 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 301839, 32, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 361, 814)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2062)
[M::mem_pestat] mean and std.dev: (500.51, 393.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2686)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (125, 174, 246)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 488)
[M::mem_pestat] mean and std.dev: (191.94, 89.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 609)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 630, 1801)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5075)
[M::mem_pestat] mean and std.dev: (894.66, 1103.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6712)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (259, 539, 1698)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4576)
[M::mem_pestat] mean and std.dev: (1006.66, 1084.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6015)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 737170 reads in 239.134 CPU sec, 8.043 real sec
[M::process] read 733236 sequences (100000118 bp) in 2.516 CPU sec, 2.910 real sec...
[M::mem_process_seqs] Processed 737002 reads in 167.428 CPU sec, 5.871 real sec
sorting block 116, #reads = 1093266 mem = 536882318 peak = 1137336320
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 302023, 23, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 352, 807)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1927)
[M::mem_pestat] mean and std.dev: (396.86, 267.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2487)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (126, 176, 251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 501)
[M::mem_pestat] mean and std.dev: (195.58, 91.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 626)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 997, 2028)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5598)
[M::mem_pestat] mean and std.dev: (1196.52, 1192.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7383)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 287, 554)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1296)
[M::mem_pestat] mean and std.dev: (344.52, 230.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1667)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 732410 sequences (100000024 bp) in 3.226 CPU sec, 3.949 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 300926, 36, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 429, 982)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2542)
[M::mem_pestat] mean and std.dev: (521.12, 465.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3322)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 178, 253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 505)
[M::mem_pestat] mean and std.dev: (197.24, 92.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 631)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (104, 193, 895)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2477)
[M::mem_pestat] mean and std.dev: (385.09, 439.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3268)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 551, 1759)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4827)
[M::mem_pestat] mean and std.dev: (951.67, 1063.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6361)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 734766 reads in 232.194 CPU sec, 7.964 real sec
[M::process] read 731908 sequences (100000009 bp) in 2.798 CPU sec, 2.965 real sec...
[M::mem_process_seqs] Processed 733236 reads in 167.559 CPU sec, 5.709 real sec
sorting block 117, #reads = 1096193 mem = 536878133 peak = 1137336320
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 300850, 46, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 317, 794)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2000)
[M::mem_pestat] mean and std.dev: (560.52, 482.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2603)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 179, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 512)
[M::mem_pestat] mean and std.dev: (199.32, 94.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 640)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 553, 1378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3780)
[M::mem_pestat] mean and std.dev: (831.19, 920.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4981)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 348, 679)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1739)
[M::mem_pestat] mean and std.dev: (457.14, 396.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2269)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 731436 sequences (100000169 bp) in 3.379 CPU sec, 3.746 real sec...
sorting block 118, #reads = 1096065 mem = 536878971 peak = 1137336320
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 300244, 48, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 469, 788)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1922)
[M::mem_pestat] mean and std.dev: (476.52, 385.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2489)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 179, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 512)
[M::mem_pestat] mean and std.dev: (199.23, 94.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 640)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (382, 558, 1027)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2317)
[M::mem_pestat] mean and std.dev: (744.87, 621.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3232)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 357, 979)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2523)
[M::mem_pestat] mean and std.dev: (647.65, 628.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3295)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 732410 reads in 230.678 CPU sec, 7.809 real sec
[M::process] read 731828 sequences (100000031 bp) in 2.767 CPU sec, 2.933 real sec...
[M::mem_process_seqs] Processed 731908 reads in 168.142 CPU sec, 5.717 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 300451, 42, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 390, 927)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2371)
[M::mem_pestat] mean and std.dev: (512.58, 444.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3093)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 179, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 512)
[M::mem_pestat] mean and std.dev: (199.20, 94.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 640)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (326, 733, 1198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2942)
[M::mem_pestat] mean and std.dev: (913.65, 846.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4298)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 298, 760)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1912)
[M::mem_pestat] mean and std.dev: (431.17, 359.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2488)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 119, #reads = 1096630 mem = 536879813 peak = 1137336320
[M::process] read 731046 sequences (100000034 bp) in 3.240 CPU sec, 3.910 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 300345, 44, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 365, 949)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2499)
[M::mem_pestat] mean and std.dev: (512.22, 470.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3274)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 179, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 512)
[M::mem_pestat] mean and std.dev: (199.37, 94.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 640)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (55, 537, 1852)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5446)
[M::mem_pestat] mean and std.dev: (741.38, 826.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7243)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 456, 987)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2505)
[M::mem_pestat] mean and std.dev: (583.62, 525.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3264)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 731436 reads in 236.037 CPU sec, 7.854 real sec
[M::mem_process_seqs] Processed 731828 reads in 169.168 CPU sec, 5.594 real sec
[M::process] read 730198 sequences (100000184 bp) in 2.953 CPU sec, 3.380 real sec...
sorting block 120, #reads = 1096170 mem = 536879420 peak = 1137336320
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 300086, 47, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 321, 1005)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2561)
[M::mem_pestat] mean and std.dev: (471.89, 519.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3339)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 180, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 515)
[M::mem_pestat] mean and std.dev: (200.30, 95.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 644)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (345, 777, 1461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3693)
[M::mem_pestat] mean and std.dev: (944.93, 762.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4809)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 250, 734)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1872)
[M::mem_pestat] mean and std.dev: (324.56, 267.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2441)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 729608 sequences (100000013 bp) in 3.201 CPU sec, 3.641 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 300033, 39, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 473, 1041)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2717)
[M::mem_pestat] mean and std.dev: (486.52, 438.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3555)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 181, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 522)
[M::mem_pestat] mean and std.dev: (202.16, 96.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 653)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 600, 700)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1618)
[M::mem_pestat] mean and std.dev: (504.81, 386.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2077)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 560, 1292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3458)
[M::mem_pestat] mean and std.dev: (812.07, 759.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4541)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 731046 reads in 236.179 CPU sec, 7.990 real sec
[M::process] read 729270 sequences (100000205 bp) in 2.885 CPU sec, 3.206 real sec...
[M::mem_process_seqs] Processed 730198 reads in 164.345 CPU sec, 5.717 real sec
sorting block 121, #reads = 1093461 mem = 536880516 peak = 1137336320
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 299856, 43, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 321, 1017)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2749)
[M::mem_pestat] mean and std.dev: (573.18, 582.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3615)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 182, 263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 531)
[M::mem_pestat] mean and std.dev: (203.90, 98.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 665)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (295, 534, 1121)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2773)
[M::mem_pestat] mean and std.dev: (660.51, 560.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3599)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 435, 977)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2427)
[M::mem_pestat] mean and std.dev: (627.19, 561.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3152)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728470 sequences (100000268 bp) in 3.522 CPU sec, 4.336 real sec...
sorting block 122, #reads = 1093713 mem = 536881824 peak = 1137336320
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 300419, 32, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (274, 592, 1326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3430)
[M::mem_pestat] mean and std.dev: (893.97, 819.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4482)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 183, 264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 534)
[M::mem_pestat] mean and std.dev: (204.58, 98.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 669)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 610, 1113)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2827)
[M::mem_pestat] mean and std.dev: (706.19, 680.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3684)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 287, 997)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2567)
[M::mem_pestat] mean and std.dev: (671.84, 688.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3427)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 729608 reads in 225.096 CPU sec, 7.724 real sec
[M::mem_process_seqs] Processed 729270 reads in 159.262 CPU sec, 5.552 real sec
[M::process] read 728306 sequences (100000225 bp) in 2.847 CPU sec, 3.140 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 299290, 29, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 391, 888)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2282)
[M::mem_pestat] mean and std.dev: (453.29, 366.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2979)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 184, 265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 535)
[M::mem_pestat] mean and std.dev: (205.13, 98.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 670)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (320, 663, 1419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3617)
[M::mem_pestat] mean and std.dev: (648.00, 565.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4716)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 465, 1444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3852)
[M::mem_pestat] mean and std.dev: (777.50, 760.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5056)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 123, #reads = 1094927 mem = 536881210 peak = 1137336320
[M::process] read 727268 sequences (100000005 bp) in 3.284 CPU sec, 3.884 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 299296, 53, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 383, 667)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1611)
[M::mem_pestat] mean and std.dev: (413.05, 272.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2083)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 184, 265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 535)
[M::mem_pestat] mean and std.dev: (205.58, 99.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 670)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 564, 1473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4079)
[M::mem_pestat] mean and std.dev: (867.32, 952.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5382)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 296, 704)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1730)
[M::mem_pestat] mean and std.dev: (427.71, 366.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2243)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 728470 reads in 227.927 CPU sec, 7.845 real sec
[M::mem_process_seqs] Processed 728306 reads in 161.153 CPU sec, 5.587 real sec
[M::process] read 726714 sequences (100000174 bp) in 2.958 CPU sec, 3.298 real sec...
sorting block 124, #reads = 1094416 mem = 536884799 peak = 1137336320
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 298662, 43, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (115, 230, 507)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1291)
[M::mem_pestat] mean and std.dev: (291.00, 229.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1683)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 185, 268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 542)
[M::mem_pestat] mean and std.dev: (207.24, 100.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 679)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (490, 786, 1440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3340)
[M::mem_pestat] mean and std.dev: (888.38, 587.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4290)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 404, 961)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2385)
[M::mem_pestat] mean and std.dev: (502.26, 411.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3097)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726248 sequences (100000162 bp) in 3.423 CPU sec, 4.238 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 298374, 44, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 361, 763)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1899)
[M::mem_pestat] mean and std.dev: (440.67, 329.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2467)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 186, 269)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 543)
[M::mem_pestat] mean and std.dev: (208.09, 100.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 680)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 604, 1194)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3240)
[M::mem_pestat] mean and std.dev: (610.61, 660.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4263)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 389, 876)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2250)
[M::mem_pestat] mean and std.dev: (614.32, 579.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2937)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 727268 reads in 233.159 CPU sec, 8.075 real sec
[M::mem_process_seqs] Processed 726714 reads in 164.320 CPU sec, 5.927 real sec
sorting block 125, #reads = 1093837 mem = 536877204 peak = 1137336320
[M::process] read 725716 sequences (100000190 bp) in 2.966 CPU sec, 3.191 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 298274, 31, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 266, 751)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1957)
[M::mem_pestat] mean and std.dev: (387.56, 398.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2560)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 186, 270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 546)
[M::mem_pestat] mean and std.dev: (208.58, 101.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 684)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 448, 1346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3592)
[M::mem_pestat] mean and std.dev: (725.14, 808.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4715)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 401, 899)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2245)
[M::mem_pestat] mean and std.dev: (598.31, 532.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2918)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 126, #reads = 1091643 mem = 536880789 peak = 1137336320
[M::process] read 725580 sequences (100000189 bp) in 3.378 CPU sec, 3.526 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 297458, 47, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 464, 1182)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3126)
[M::mem_pestat] mean and std.dev: (663.75, 689.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4098)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 187, 270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 546)
[M::mem_pestat] mean and std.dev: (208.84, 101.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 684)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (107, 435, 853)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2345)
[M::mem_pestat] mean and std.dev: (529.26, 541.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3091)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (294, 503, 1212)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3048)
[M::mem_pestat] mean and std.dev: (799.27, 746.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3966)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 726248 reads in 217.269 CPU sec, 6.947 real sec
[M::process] read 725342 sequences (100000237 bp) in 2.194 CPU sec, 2.208 real sec...
[M::mem_process_seqs] Processed 725716 reads in 152.643 CPU sec, 5.070 real sec
sorting block 127, #reads = 1091607 mem = 536878891 peak = 1137336320
[M::process] read 724814 sequences (100000269 bp) in 3.041 CPU sec, 3.222 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 297704, 49, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 306, 1824)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5162)
[M::mem_pestat] mean and std.dev: (733.50, 945.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6831)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 187, 269)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 543)
[M::mem_pestat] mean and std.dev: (208.46, 100.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 680)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (71, 537, 1200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3458)
[M::mem_pestat] mean and std.dev: (683.62, 779.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4587)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 318, 928)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2304)
[M::mem_pestat] mean and std.dev: (520.69, 475.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2992)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724032 sequences (100000074 bp) in 2.556 CPU sec, 2.565 real sec...
[M::mem_process_seqs] Processed 725342 reads in 132.282 CPU sec, 4.212 real sec
sorting block 128, #reads = 1091263 mem = 536880958 peak = 1137336320
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 297733, 35, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 324, 809)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2085)
[M::mem_pestat] mean and std.dev: (510.56, 486.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2723)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 187, 270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 546)
[M::mem_pestat] mean and std.dev: (208.80, 100.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 684)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (398, 659, 913)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1943)
[M::mem_pestat] mean and std.dev: (691.61, 409.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2458)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (265, 694, 1223)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3139)
[M::mem_pestat] mean and std.dev: (789.82, 614.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4097)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 297154, 47, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 536, 1498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4000)
[M::mem_pestat] mean and std.dev: (724.71, 685.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5251)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 188, 270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 544)
[M::mem_pestat] mean and std.dev: (209.40, 100.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 681)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (259, 516, 1372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3598)
[M::mem_pestat] mean and std.dev: (873.09, 967.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4743)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 423, 949)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2391)
[M::mem_pestat] mean and std.dev: (533.83, 419.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3112)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 725580 reads in 341.704 CPU sec, 11.137 real sec
[M::process] read 724130 sequences (100000038 bp) in 2.813 CPU sec, 2.875 real sec...
[M::mem_process_seqs] Processed 724814 reads in 188.837 CPU sec, 6.086 real sec
sorting block 129, #reads = 1090189 mem = 536883453 peak = 1137336320
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 297383, 27, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 420, 823)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2005)
[M::mem_pestat] mean and std.dev: (515.55, 383.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2596)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 189, 272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 550)
[M::mem_pestat] mean and std.dev: (210.40, 101.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 689)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 391, 2753)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7963)
[M::mem_pestat] mean and std.dev: (1232.31, 1682.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10568)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 467, 1059)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2751)
[M::mem_pestat] mean and std.dev: (603.32, 548.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3597)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723650 sequences (100000057 bp) in 3.016 CPU sec, 3.278 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 297544, 35, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 420, 1616)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4400)
[M::mem_pestat] mean and std.dev: (962.98, 1038.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5792)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 189, 272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 550)
[M::mem_pestat] mean and std.dev: (210.49, 101.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 689)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (108, 220, 980)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2724)
[M::mem_pestat] mean and std.dev: (492.09, 580.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3596)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (306, 715, 1236)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3096)
[M::mem_pestat] mean and std.dev: (795.44, 587.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4026)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724032 reads in 216.965 CPU sec, 7.103 real sec
[M::process] read 724748 sequences (100000102 bp) in 2.542 CPU sec, 2.660 real sec...
[M::mem_process_seqs] Processed 724130 reads in 152.851 CPU sec, 5.238 real sec
sorting block 130, #reads = 1091335 mem = 536878280 peak = 1137336320
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 297264, 44, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 275, 581)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1389)
[M::mem_pestat] mean and std.dev: (382.76, 300.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1793)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 189, 272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 550)
[M::mem_pestat] mean and std.dev: (210.49, 101.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 689)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 568, 1259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3341)
[M::mem_pestat] mean and std.dev: (630.05, 590.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4382)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 500, 1202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3236)
[M::mem_pestat] mean and std.dev: (682.54, 636.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4253)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724252 sequences (100000201 bp) in 3.073 CPU sec, 3.532 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 297496, 44, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 384, 869)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2131)
[M::mem_pestat] mean and std.dev: (476.10, 416.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2762)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 188, 271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 547)
[M::mem_pestat] mean and std.dev: (209.53, 101.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 685)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 504, 1251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3481)
[M::mem_pestat] mean and std.dev: (616.75, 719.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4596)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 420, 800)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2020)
[M::mem_pestat] mean and std.dev: (517.21, 390.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2630)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723982 sequences (100000259 bp) in 2.617 CPU sec, 2.629 real sec...
[M::mem_process_seqs] Processed 723650 reads in 224.314 CPU sec, 7.591 real sec
sorting block 131, #reads = 1091869 mem = 536878049 peak = 1137336320
[M::mem_process_seqs] Processed 724748 reads in 156.338 CPU sec, 5.125 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 297657, 40, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (307, 594, 1216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3034)
[M::mem_pestat] mean and std.dev: (799.98, 676.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3943)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 188, 271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 547)
[M::mem_pestat] mean and std.dev: (210.00, 101.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 685)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 555, 1352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3684)
[M::mem_pestat] mean and std.dev: (840.34, 967.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4850)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 426, 703)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1723)
[M::mem_pestat] mean and std.dev: (472.61, 360.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2233)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723876 sequences (100000150 bp) in 3.415 CPU sec, 3.772 real sec...
sorting block 132, #reads = 1091333 mem = 536878792 peak = 1137336320
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 297191, 25, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 321, 836)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2082)
[M::mem_pestat] mean and std.dev: (456.28, 381.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2705)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 189, 273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 553)
[M::mem_pestat] mean and std.dev: (210.81, 101.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 693)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (442, 1091, 1759)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4393)
[M::mem_pestat] mean and std.dev: (816.62, 563.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5710)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 387, 1069)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2751)
[M::mem_pestat] mean and std.dev: (651.78, 625.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3592)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724252 reads in 222.568 CPU sec, 7.281 real sec
[M::mem_process_seqs] Processed 723982 reads in 159.623 CPU sec, 5.135 real sec
[M::process] read 724358 sequences (100000002 bp) in 2.962 CPU sec, 3.179 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 297216, 42, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 455, 1145)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3005)
[M::mem_pestat] mean and std.dev: (712.17, 646.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3935)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 189, 273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 553)
[M::mem_pestat] mean and std.dev: (211.21, 102.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 693)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 687, 1135)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2959)
[M::mem_pestat] mean and std.dev: (711.75, 546.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3871)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (282, 474, 1091)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2709)
[M::mem_pestat] mean and std.dev: (687.25, 616.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3518)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 133, #reads = 1091156 mem = 536879469 peak = 1137336320
[M::process] read 724668 sequences (100000246 bp) in 3.498 CPU sec, 3.895 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 297454, 52, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (300, 660, 1621)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4263)
[M::mem_pestat] mean and std.dev: (1108.88, 1064.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5584)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 188, 272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 550)
[M::mem_pestat] mean and std.dev: (210.19, 101.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 689)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (360, 512, 1496)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3768)
[M::mem_pestat] mean and std.dev: (714.15, 712.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4904)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (313, 922, 2024)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5446)
[M::mem_pestat] mean and std.dev: (1407.96, 1395.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7157)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723876 reads in 231.574 CPU sec, 7.677 real sec
[M::mem_process_seqs] Processed 724358 reads in 165.604 CPU sec, 5.497 real sec
[M::process] read 729146 sequences (100000121 bp) in 3.155 CPU sec, 3.408 real sec...
sorting block 134, #reads = 1092067 mem = 536879112 peak = 1137336320
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 296990, 24, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 351, 771)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1899)
[M::mem_pestat] mean and std.dev: (440.07, 343.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2463)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 187, 270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 544)
[M::mem_pestat] mean and std.dev: (208.94, 100.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 681)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (335, 684, 1560)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4010)
[M::mem_pestat] mean and std.dev: (783.59, 623.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5235)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 382, 985)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2529)
[M::mem_pestat] mean and std.dev: (578.95, 612.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3301)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 734910 sequences (100000166 bp) in 3.477 CPU sec, 3.847 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 297664, 47, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 439, 1014)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2654)
[M::mem_pestat] mean and std.dev: (671.23, 649.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3474)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 182, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 523)
[M::mem_pestat] mean and std.dev: (202.87, 97.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 654)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 630, 2753)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7791)
[M::mem_pestat] mean and std.dev: (1545.98, 1814.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10310)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 433, 1476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3994)
[M::mem_pestat] mean and std.dev: (754.78, 874.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5253)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 733342 sequences (100000091 bp) in 2.652 CPU sec, 2.673 real sec...
[M::mem_process_seqs] Processed 724668 reads in 260.777 CPU sec, 8.404 real sec
sorting block 135, #reads = 1091010 mem = 536879234 peak = 1137336320
[M::mem_process_seqs] Processed 729146 reads in 195.931 CPU sec, 6.359 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 301685, 45, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 580, 993)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2597)
[M::mem_pestat] mean and std.dev: (640.88, 584.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3399)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (126, 175, 249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 495)
[M::mem_pestat] mean and std.dev: (194.20, 90.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 618)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (273, 730, 1685)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4509)
[M::mem_pestat] mean and std.dev: (1005.63, 933.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5921)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 396, 932)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2372)
[M::mem_pestat] mean and std.dev: (622.13, 574.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3092)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 136, #reads = 1082264 mem = 536881528 peak = 1137336320
[M::process] read 731662 sequences (100000109 bp) in 3.237 CPU sec, 3.538 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 301177, 33, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (305, 766, 1395)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3575)
[M::mem_pestat] mean and std.dev: (823.91, 563.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4665)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 178, 253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 505)
[M::mem_pestat] mean and std.dev: (197.19, 93.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 631)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (72, 259, 1281)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3699)
[M::mem_pestat] mean and std.dev: (666.97, 805.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4908)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 374, 963)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2449)
[M::mem_pestat] mean and std.dev: (518.66, 439.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3192)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 734910 reads in 228.654 CPU sec, 7.461 real sec
[M::process] read 730850 sequences (100000047 bp) in 2.615 CPU sec, 2.664 real sec...
[M::mem_process_seqs] Processed 733342 reads in 159.440 CPU sec, 5.363 real sec
sorting block 137, #reads = 1095159 mem = 536887320 peak = 1137336320
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 300519, 26, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 303, 962)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2530)
[M::mem_pestat] mean and std.dev: (475.69, 517.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3314)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 180, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 515)
[M::mem_pestat] mean and std.dev: (200.13, 95.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 644)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 623, 1674)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4534)
[M::mem_pestat] mean and std.dev: (855.67, 865.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5964)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (344, 617, 1120)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2672)
[M::mem_pestat] mean and std.dev: (615.89, 403.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3448)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 730670 sequences (100000181 bp) in 3.633 CPU sec, 4.037 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 300577, 56, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 438, 1322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3516)
[M::mem_pestat] mean and std.dev: (687.80, 651.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4613)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 181, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 521)
[M::mem_pestat] mean and std.dev: (201.12, 95.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 652)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 585, 861)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2293)
[M::mem_pestat] mean and std.dev: (503.90, 442.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3009)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 343, 1123)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2923)
[M::mem_pestat] mean and std.dev: (636.00, 643.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3823)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 731662 reads in 224.344 CPU sec, 7.528 real sec
[M::process] read 730166 sequences (100000109 bp) in 2.845 CPU sec, 2.902 real sec...
[M::mem_process_seqs] Processed 730850 reads in 157.549 CPU sec, 5.191 real sec
sorting block 138, #reads = 1098224 mem = 536879539 peak = 1137336320
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 300877, 51, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 472, 1265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3367)
[M::mem_pestat] mean and std.dev: (653.46, 659.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4418)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 181, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 525)
[M::mem_pestat] mean and std.dev: (202.09, 96.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 657)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 547, 1431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3971)
[M::mem_pestat] mean and std.dev: (757.83, 740.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5241)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 371, 592)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1390)
[M::mem_pestat] mean and std.dev: (375.33, 214.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1789)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 729396 sequences (100000096 bp) in 3.352 CPU sec, 3.665 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 300179, 34, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 483, 697)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1707)
[M::mem_pestat] mean and std.dev: (441.10, 312.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2212)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 181, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 522)
[M::mem_pestat] mean and std.dev: (201.89, 96.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 653)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (281, 438, 1025)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2513)
[M::mem_pestat] mean and std.dev: (501.97, 406.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3257)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 320, 852)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2194)
[M::mem_pestat] mean and std.dev: (440.34, 377.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2865)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 730670 reads in 224.212 CPU sec, 7.445 real sec
sorting block 139, #reads = 1098465 mem = 536883002 peak = 1137336320
[M::mem_process_seqs] Processed 730166 reads in 159.480 CPU sec, 5.116 real sec
[M::process] read 729174 sequences (100000230 bp) in 3.084 CPU sec, 3.243 real sec...
sorting block 140, #reads = 1097511 mem = 536881015 peak = 1137336320
[M::process] read 728542 sequences (100000249 bp) in 3.250 CPU sec, 3.572 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 300020, 43, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 455, 1015)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2565)
[M::mem_pestat] mean and std.dev: (681.32, 589.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3340)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 182, 263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 531)
[M::mem_pestat] mean and std.dev: (203.87, 98.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 665)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 284, 766)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1976)
[M::mem_pestat] mean and std.dev: (410.12, 365.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2581)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (290, 432, 2997)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8411)
[M::mem_pestat] mean and std.dev: (1438.57, 1829.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11118)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 729174 reads in 128.492 CPU sec, 4.075 real sec
[M::process] read 728688 sequences (100000163 bp) in 2.834 CPU sec, 2.900 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 300057, 39, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 269, 714)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1730)
[M::mem_pestat] mean and std.dev: (351.58, 283.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2238)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 183, 262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 526)
[M::mem_pestat] mean and std.dev: (203.65, 97.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 658)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 450, 1572)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4292)
[M::mem_pestat] mean and std.dev: (887.41, 1020.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5652)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 387, 915)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2281)
[M::mem_pestat] mean and std.dev: (527.31, 475.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2964)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 299512, 29, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 429, 959)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2347)
[M::mem_pestat] mean and std.dev: (681.81, 584.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3041)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 184, 265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 535)
[M::mem_pestat] mean and std.dev: (205.24, 99.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 670)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 524, 1115)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2965)
[M::mem_pestat] mean and std.dev: (564.40, 574.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3890)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 367, 850)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2152)
[M::mem_pestat] mean and std.dev: (527.55, 476.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2803)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 729396 reads in 348.749 CPU sec, 11.232 real sec
sorting block 141, #reads = 1095580 mem = 536881117 peak = 1137336320
[M::mem_process_seqs] Processed 728542 reads in 185.149 CPU sec, 5.934 real sec
[M::process] read 728512 sequences (100000244 bp) in 3.226 CPU sec, 3.342 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 299750, 46, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 321, 1110)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2982)
[M::mem_pestat] mean and std.dev: (629.98, 715.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3918)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 183, 264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 532)
[M::mem_pestat] mean and std.dev: (204.36, 98.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 666)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 906, 2123)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6033)
[M::mem_pestat] mean and std.dev: (1540.48, 1748.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8533)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 315, 1834)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5076)
[M::mem_pestat] mean and std.dev: (879.28, 1128.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6697)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 142, #reads = 1097103 mem = 536878496 peak = 1137336320
[M::process] read 728152 sequences (100000069 bp) in 3.563 CPU sec, 3.847 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 300029, 37, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 446, 727)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1733)
[M::mem_pestat] mean and std.dev: (450.27, 319.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2236)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 183, 264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 532)
[M::mem_pestat] mean and std.dev: (205.09, 99.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 666)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 361, 753)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1931)
[M::mem_pestat] mean and std.dev: (476.31, 407.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2520)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 396, 1029)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2585)
[M::mem_pestat] mean and std.dev: (625.30, 580.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3363)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 728688 reads in 229.577 CPU sec, 7.425 real sec
[M::process] read 727878 sequences (100000009 bp) in 2.781 CPU sec, 2.854 real sec...
[M::mem_process_seqs] Processed 728512 reads in 165.350 CPU sec, 5.472 real sec
sorting block 143, #reads = 1095595 mem = 536877137 peak = 1137336320
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 299525, 44, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (302, 388, 1298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3290)
[M::mem_pestat] mean and std.dev: (675.38, 602.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4286)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 184, 265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 535)
[M::mem_pestat] mean and std.dev: (205.60, 99.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 670)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 482, 1396)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3708)
[M::mem_pestat] mean and std.dev: (624.16, 612.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4864)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 258, 934)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2368)
[M::mem_pestat] mean and std.dev: (585.10, 597.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3085)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728216 sequences (100000258 bp) in 3.107 CPU sec, 3.347 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 299500, 39, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 357, 598)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1358)
[M::mem_pestat] mean and std.dev: (400.96, 261.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1738)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 267)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 539)
[M::mem_pestat] mean and std.dev: (206.64, 100.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 675)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (276, 576, 1241)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3171)
[M::mem_pestat] mean and std.dev: (720.24, 633.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4136)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 294, 795)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2029)
[M::mem_pestat] mean and std.dev: (451.53, 399.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2646)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727476 sequences (100000258 bp) in 2.471 CPU sec, 2.482 real sec...
[M::mem_process_seqs] Processed 728152 reads in 233.826 CPU sec, 7.672 real sec
sorting block 144, #reads = 1094934 mem = 536881441 peak = 1137336320
[M::mem_process_seqs] Processed 727878 reads in 154.661 CPU sec, 5.042 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 299324, 32, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 225, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 650)
[M::mem_pestat] mean and std.dev: (220.67, 90.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 808)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 184, 266)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 538)
[M::mem_pestat] mean and std.dev: (205.93, 99.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 674)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (252, 442, 1688)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4560)
[M::mem_pestat] mean and std.dev: (1021.97, 1159.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5996)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (371, 462, 1045)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2393)
[M::mem_pestat] mean and std.dev: (601.95, 423.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3067)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726678 sequences (100000099 bp) in 3.117 CPU sec, 3.278 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 299514, 33, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 313, 746)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1828)
[M::mem_pestat] mean and std.dev: (462.05, 371.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2369)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 185, 268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 542)
[M::mem_pestat] mean and std.dev: (207.09, 100.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 679)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 722, 2458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7016)
[M::mem_pestat] mean and std.dev: (1616.85, 1891.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9295)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (284, 392, 743)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1661)
[M::mem_pestat] mean and std.dev: (412.49, 261.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2120)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725978 sequences (100000209 bp) in 1.980 CPU sec, 1.972 real sec...
[M::mem_process_seqs] Processed 728216 reads in 199.223 CPU sec, 6.455 real sec
sorting block 145, #reads = 1093224 mem = 536878653 peak = 1137336320
[M::mem_process_seqs] Processed 727476 reads in 137.531 CPU sec, 4.394 real sec
sorting block 146, #reads = 1095465 mem = 536878770 peak = 1137336320
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 298662, 52, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 471, 1588)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4296)
[M::mem_pestat] mean and std.dev: (907.38, 798.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5650)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 186, 269)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 545)
[M::mem_pestat] mean and std.dev: (208.22, 101.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 683)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 532, 1000)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2532)
[M::mem_pestat] mean and std.dev: (613.06, 560.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3298)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (258, 624, 1362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3570)
[M::mem_pestat] mean and std.dev: (808.77, 659.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4674)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724856 sequences (100000101 bp) in 2.679 CPU sec, 2.752 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 298588, 45, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 401, 1209)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3263)
[M::mem_pestat] mean and std.dev: (668.98, 702.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4290)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 186, 270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 546)
[M::mem_pestat] mean and std.dev: (208.60, 101.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 684)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (358, 629, 1133)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2683)
[M::mem_pestat] mean and std.dev: (600.69, 510.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3458)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 289, 627)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1529)
[M::mem_pestat] mean and std.dev: (377.92, 298.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1980)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724936 sequences (100000220 bp) in 2.398 CPU sec, 2.401 real sec...
[M::mem_process_seqs] Processed 726678 reads in 187.729 CPU sec, 5.933 real sec
[M::mem_process_seqs] Processed 725978 reads in 133.975 CPU sec, 4.322 real sec
sorting block 147, #reads = 1094473 mem = 536878463 peak = 1137336320
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 297344, 40, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 339, 780)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1954)
[M::mem_pestat] mean and std.dev: (469.97, 387.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2541)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 188, 272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 550)
[M::mem_pestat] mean and std.dev: (210.61, 102.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 689)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 410, 1514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4088)
[M::mem_pestat] mean and std.dev: (913.10, 1047.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5375)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 435, 808)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1920)
[M::mem_pestat] mean and std.dev: (462.82, 345.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2476)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724618 sequences (100000183 bp) in 2.595 CPU sec, 2.661 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 297337, 47, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 588, 929)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2449)
[M::mem_pestat] mean and std.dev: (519.16, 404.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3209)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 188, 272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 550)
[M::mem_pestat] mean and std.dev: (210.14, 101.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 689)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 806, 1163)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3067)
[M::mem_pestat] mean and std.dev: (766.80, 635.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4019)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 307, 637)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1551)
[M::mem_pestat] mean and std.dev: (339.67, 249.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2008)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724764 sequences (100000034 bp) in 2.170 CPU sec, 2.174 real sec...
[M::mem_process_seqs] Processed 724856 reads in 177.142 CPU sec, 5.686 real sec
sorting block 148, #reads = 1090284 mem = 536880193 peak = 1137336320
[M::mem_process_seqs] Processed 724936 reads in 120.254 CPU sec, 3.886 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 297635, 36, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 406, 904)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2334)
[M::mem_pestat] mean and std.dev: (555.55, 471.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3049)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 188, 272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 550)
[M::mem_pestat] mean and std.dev: (210.30, 101.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 689)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (353, 566, 1912)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5030)
[M::mem_pestat] mean and std.dev: (1088.97, 1253.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6589)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 454, 1309)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3509)
[M::mem_pestat] mean and std.dev: (682.83, 670.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4609)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724228 sequences (100000227 bp) in 2.696 CPU sec, 2.739 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 297358, 27, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 356, 656)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1566)
[M::mem_pestat] mean and std.dev: (408.21, 315.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2021)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 189, 271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 547)
[M::mem_pestat] mean and std.dev: (209.82, 100.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 685)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (426, 529, 933)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1947)
[M::mem_pestat] mean and std.dev: (660.19, 441.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2454)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 376, 1054)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2706)
[M::mem_pestat] mean and std.dev: (580.04, 521.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3532)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724476 sequences (100000170 bp) in 2.230 CPU sec, 2.230 real sec...
[M::mem_process_seqs] Processed 724618 reads in 177.209 CPU sec, 5.659 real sec
sorting block 149, #reads = 1089985 mem = 536879666 peak = 1137336320
[M::mem_process_seqs] Processed 724764 reads in 122.916 CPU sec, 3.892 real sec
sorting block 150, #reads = 1091211 mem = 536880175 peak = 1137336320
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 297918, 45, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 380, 972)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2448)
[M::mem_pestat] mean and std.dev: (593.83, 544.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3186)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 189, 272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 550)
[M::mem_pestat] mean and std.dev: (210.37, 101.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 689)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (255, 623, 1175)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3015)
[M::mem_pestat] mean and std.dev: (756.61, 662.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3935)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 364, 973)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2471)
[M::mem_pestat] mean and std.dev: (587.92, 547.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3220)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724676 sequences (100000024 bp) in 2.385 CPU sec, 2.432 real sec...
[M::process] read 723964 sequences (100000122 bp) in 1.919 CPU sec, 1.917 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (79, 297964, 38, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 385, 1131)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2863)
[M::mem_pestat] mean and std.dev: (592.70, 625.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3729)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 188, 271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 547)
[M::mem_pestat] mean and std.dev: (209.67, 101.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 685)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (428, 657, 1344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3176)
[M::mem_pestat] mean and std.dev: (645.03, 479.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4092)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 368, 548)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1254)
[M::mem_pestat] mean and std.dev: (379.32, 233.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1607)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724228 reads in 186.503 CPU sec, 5.959 real sec
[M::mem_process_seqs] Processed 724476 reads in 130.314 CPU sec, 4.273 real sec
sorting block 151, #reads = 1091649 mem = 536879815 peak = 1137336320
[M::process] read 723836 sequences (100000088 bp) in 2.339 CPU sec, 2.398 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 297603, 34, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 383, 885)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2181)
[M::mem_pestat] mean and std.dev: (573.26, 526.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2829)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 187, 270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 544)
[M::mem_pestat] mean and std.dev: (209.06, 100.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 681)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (295, 623, 1808)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4834)
[M::mem_pestat] mean and std.dev: (755.69, 756.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6347)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (302, 804, 1537)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4007)
[M::mem_pestat] mean and std.dev: (956.57, 791.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5242)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723780 sequences (100000293 bp) in 1.810 CPU sec, 1.812 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 297084, 46, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 231, 610)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1470)
[M::mem_pestat] mean and std.dev: (367.20, 314.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1900)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 189, 272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 550)
[M::mem_pestat] mean and std.dev: (210.58, 101.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 689)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (85, 617, 1230)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3520)
[M::mem_pestat] mean and std.dev: (603.71, 584.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4665)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 428, 1962)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5434)
[M::mem_pestat] mean and std.dev: (872.41, 956.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7170)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 297275, 52, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 676, 1726)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4726)
[M::mem_pestat] mean and std.dev: (803.82, 800.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6226)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 189, 273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 553)
[M::mem_pestat] mean and std.dev: (211.06, 101.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 693)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (253, 603, 985)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2449)
[M::mem_pestat] mean and std.dev: (645.21, 540.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3181)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 375, 586)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1302)
[M::mem_pestat] mean and std.dev: (431.56, 292.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1660)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724676 reads in 274.008 CPU sec, 8.869 real sec
sorting block 152, #reads = 1090423 mem = 536878609 peak = 1137336320
[M::mem_process_seqs] Processed 723836 reads in 212.219 CPU sec, 6.808 real sec
[M::mem_process_seqs] Processed 723964 reads in 244.746 CPU sec, 7.856 real sec
sorting block 153, #reads = 1090615 mem = 536878339 peak = 1137336320
[M::process] read 724074 sequences (100000191 bp) in 2.332 CPU sec, 2.441 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 297083, 53, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 397, 658)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1462)
[M::mem_pestat] mean and std.dev: (453.67, 279.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1864)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 189, 273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 553)
[M::mem_pestat] mean and std.dev: (211.04, 101.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 693)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 545, 1310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3570)
[M::mem_pestat] mean and std.dev: (647.87, 556.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4700)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 305, 631)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1537)
[M::mem_pestat] mean and std.dev: (355.06, 277.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1990)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724168 sequences (100000261 bp) in 2.443 CPU sec, 2.475 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 296622, 22, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 250, 1218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3316)
[M::mem_pestat] mean and std.dev: (556.46, 638.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4365)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 189, 271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 547)
[M::mem_pestat] mean and std.dev: (210.04, 101.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 685)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (260, 667, 894)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2162)
[M::mem_pestat] mean and std.dev: (556.84, 411.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2796)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 422, 809)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2021)
[M::mem_pestat] mean and std.dev: (531.44, 418.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2627)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723780 reads in 178.290 CPU sec, 5.645 real sec
[M::mem_process_seqs] Processed 724074 reads in 127.345 CPU sec, 3.997 real sec
sorting block 154, #reads = 1085368 mem = 536879616 peak = 1137336320
[M::process] read 724398 sequences (100000134 bp) in 2.474 CPU sec, 2.497 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 297084, 76, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 262, 663)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1625)
[M::mem_pestat] mean and std.dev: (392.21, 355.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2106)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 188, 272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 550)
[M::mem_pestat] mean and std.dev: (210.18, 101.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 689)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 539, 1606)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4376)
[M::mem_pestat] mean and std.dev: (871.45, 964.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5761)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 539, 1084)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2754)
[M::mem_pestat] mean and std.dev: (616.29, 492.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3589)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725538 sequences (100000013 bp) in 2.772 CPU sec, 2.810 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 296807, 49, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 364, 899)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2243)
[M::mem_pestat] mean and std.dev: (508.74, 392.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2915)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 188, 271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 547)
[M::mem_pestat] mean and std.dev: (209.63, 101.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 685)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (130, 636, 1567)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4441)
[M::mem_pestat] mean and std.dev: (806.33, 798.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5878)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 363, 1106)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2880)
[M::mem_pestat] mean and std.dev: (577.04, 534.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3767)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 736970 sequences (100000017 bp) in 2.170 CPU sec, 2.176 real sec...
[M::mem_process_seqs] Processed 724168 reads in 175.938 CPU sec, 5.557 real sec
sorting block 155, #reads = 1088627 mem = 536880011 peak = 1137336320
[M::mem_process_seqs] Processed 724398 reads in 123.831 CPU sec, 3.902 real sec
sorting block 156, #reads = 1087931 mem = 536880333 peak = 1177673728
[M::process] read 737708 sequences (100000294 bp) in 2.518 CPU sec, 2.591 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 296315, 39, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 386, 812)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1968)
[M::mem_pestat] mean and std.dev: (469.43, 397.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2546)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 186, 267)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 537)
[M::mem_pestat] mean and std.dev: (207.30, 99.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 672)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (69, 180, 770)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2172)
[M::mem_pestat] mean and std.dev: (346.62, 422.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2873)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 290, 1440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3938)
[M::mem_pestat] mean and std.dev: (819.52, 894.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5187)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 735576 sequences (100000015 bp) in 1.720 CPU sec, 1.717 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 301363, 49, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 421, 898)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2278)
[M::mem_pestat] mean and std.dev: (517.57, 438.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2968)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (125, 174, 245)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 485)
[M::mem_pestat] mean and std.dev: (191.35, 88.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 605)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (302, 710, 1599)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4193)
[M::mem_pestat] mean and std.dev: (791.46, 637.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5490)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (278, 385, 905)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2159)
[M::mem_pestat] mean and std.dev: (531.69, 426.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2786)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 725538 reads in 192.658 CPU sec, 6.110 real sec
[M::mem_process_seqs] Processed 736970 reads in 218.709 CPU sec, 6.959 real sec
sorting block 157, #reads = 1081462 mem = 536882805 peak = 1177673728
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 301946, 40, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 405, 978)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2568)
[M::mem_pestat] mean and std.dev: (596.44, 569.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3363)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (124, 173, 243)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 481)
[M::mem_pestat] mean and std.dev: (190.34, 87.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 600)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 627, 1372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3674)
[M::mem_pestat] mean and std.dev: (866.16, 839.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4825)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 409, 1048)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2742)
[M::mem_pestat] mean and std.dev: (639.91, 571.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3589)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 734662 sequences (100000015 bp) in 2.907 CPU sec, 2.949 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 302061, 24, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (124, 262, 1193)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3331)
[M::mem_pestat] mean and std.dev: (645.05, 759.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4400)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (126, 175, 249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 495)
[M::mem_pestat] mean and std.dev: (194.16, 90.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 618)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 380, 932)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2428)
[M::mem_pestat] mean and std.dev: (566.92, 456.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3176)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (268, 410, 1002)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2470)
[M::mem_pestat] mean and std.dev: (628.33, 531.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3204)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 733702 sequences (100000151 bp) in 1.970 CPU sec, 1.963 real sec...
[M::mem_process_seqs] Processed 737708 reads in 173.206 CPU sec, 5.475 real sec
sorting block 158, #reads = 1090898 mem = 536880194 peak = 1177673728
[M::mem_process_seqs] Processed 735576 reads in 200.417 CPU sec, 6.364 real sec
sorting block 159, #reads = 1095612 mem = 536879324 peak = 1177673728
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 301385, 36, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 403, 1125)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3011)
[M::mem_pestat] mean and std.dev: (715.38, 767.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3954)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 732540 sequences (100000050 bp) in 2.232 CPU sec, 2.281 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (126, 176, 250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 498)
[M::mem_pestat] mean and std.dev: (194.84, 91.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 622)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 628, 1858)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5124)
[M::mem_pestat] mean and std.dev: (829.00, 901.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6757)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 388, 901)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2261)
[M::mem_pestat] mean and std.dev: (537.84, 451.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2941)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 734474 sequences (100000246 bp) in 1.720 CPU sec, 1.721 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 301521, 44, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 550, 1881)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5201)
[M::mem_pestat] mean and std.dev: (958.31, 1092.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6861)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 177, 252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 502)
[M::mem_pestat] mean and std.dev: (196.57, 92.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 627)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 459, 896)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2350)
[M::mem_pestat] mean and std.dev: (554.31, 472.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3077)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 386, 784)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2016)
[M::mem_pestat] mean and std.dev: (491.59, 412.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2632)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 734662 reads in 170.389 CPU sec, 5.399 real sec
[M::mem_process_seqs] Processed 733702 reads in 115.565 CPU sec, 3.680 real sec
sorting block 160, #reads = 1096140 mem = 536883909 peak = 1177673728
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 301109, 40, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 352, 934)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2476)
[M::mem_pestat] mean and std.dev: (443.92, 400.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3247)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 178, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 508)
[M::mem_pestat] mean and std.dev: (197.96, 93.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 635)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (118, 698, 1663)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4753)
[M::mem_pestat] mean and std.dev: (852.50, 848.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6298)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 339, 811)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1991)
[M::mem_pestat] mean and std.dev: (431.38, 353.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2581)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 734576 sequences (100000133 bp) in 2.853 CPU sec, 2.963 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 301810, 35, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 292, 689)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1725)
[M::mem_pestat] mean and std.dev: (303.20, 230.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2243)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (126, 177, 251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 501)
[M::mem_pestat] mean and std.dev: (195.55, 91.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 626)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (127, 258, 1111)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3079)
[M::mem_pestat] mean and std.dev: (588.44, 692.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4063)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 461, 1314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3552)
[M::mem_pestat] mean and std.dev: (706.24, 628.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4671)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 732804 sequences (100000215 bp) in 1.960 CPU sec, 1.957 real sec...
[M::mem_process_seqs] Processed 732540 reads in 166.994 CPU sec, 5.276 real sec
[M::mem_process_seqs] Processed 734474 reads in 116.986 CPU sec, 3.698 real sec
sorting block 161, #reads = 1096512 mem = 536880082 peak = 1177673728
[M::process] read 731442 sequences (100000033 bp) in 2.372 CPU sec, 2.418 real sec...
[M::process] read 732914 sequences (100000088 bp) in 1.740 CPU sec, 1.738 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 300333, 45, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 437, 1393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3723)
[M::mem_pestat] mean and std.dev: (678.10, 585.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4888)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 179, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 515)
[M::mem_pestat] mean and std.dev: (199.74, 94.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 644)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (290, 407, 603)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1229)
[M::mem_pestat] mean and std.dev: (423.57, 261.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1542)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (272, 435, 1705)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4571)
[M::mem_pestat] mean and std.dev: (799.87, 712.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6004)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 731442 reads in 91.198 CPU sec, 2.891 real sec
sorting block 162, #reads = 1094716 mem = 536887102 peak = 1177673728
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 301442, 28, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 346, 797)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1999)
[M::mem_pestat] mean and std.dev: (456.33, 410.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2600)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (126, 176, 249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 495)
[M::mem_pestat] mean and std.dev: (194.55, 90.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 618)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (116, 773, 2862)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8354)
[M::mem_pestat] mean and std.dev: (1471.61, 1695.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11100)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (309, 531, 1159)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2859)
[M::mem_pestat] mean and std.dev: (730.63, 606.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3709)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 301115, 25, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (326, 855, 1349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3395)
[M::mem_pestat] mean and std.dev: (816.15, 680.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4418)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 178, 253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 505)
[M::mem_pestat] mean and std.dev: (197.29, 93.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 631)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (412, 610, 1686)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4234)
[M::mem_pestat] mean and std.dev: (965.17, 763.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5508)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 318, 702)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1756)
[M::mem_pestat] mean and std.dev: (486.03, 388.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2283)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 730236 sequences (100000252 bp) in 2.143 CPU sec, 2.150 real sec...
[M::mem_process_seqs] Processed 734576 reads in 266.902 CPU sec, 8.444 real sec
sorting block 163, #reads = 1092061 mem = 536878804 peak = 1177673728
[M::mem_process_seqs] Processed 732804 reads in 207.044 CPU sec, 6.572 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 300080, 55, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (275, 392, 1027)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2531)
[M::mem_pestat] mean and std.dev: (612.85, 482.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3283)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 180, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 519)
[M::mem_pestat] mean and std.dev: (201.13, 95.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 649)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (402, 629, 1449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3543)
[M::mem_pestat] mean and std.dev: (776.38, 660.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4590)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 387, 784)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1876)
[M::mem_pestat] mean and std.dev: (469.86, 322.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2422)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 730422 sequences (100000292 bp) in 2.438 CPU sec, 2.481 real sec...
[M::process] read 730308 sequences (100000103 bp) in 1.710 CPU sec, 1.706 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 301141, 31, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 349, 1121)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2915)
[M::mem_pestat] mean and std.dev: (569.67, 527.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3812)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 177, 250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 496)
[M::mem_pestat] mean and std.dev: (195.31, 90.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 619)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 360, 1060)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2870)
[M::mem_pestat] mean and std.dev: (556.46, 527.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3775)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 228, 491)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1215)
[M::mem_pestat] mean and std.dev: (278.47, 250.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1577)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 730236 reads in 159.728 CPU sec, 5.064 real sec
sorting block 164, #reads = 1094797 mem = 536885479 peak = 1177673728
[M::mem_process_seqs] Processed 732914 reads in 181.351 CPU sec, 5.768 real sec
sorting block 165, #reads = 1093558 mem = 536878443 peak = 1177673728
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 300592, 52, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 381, 854)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2160)
[M::mem_pestat] mean and std.dev: (541.84, 450.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2813)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 180, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 519)
[M::mem_pestat] mean and std.dev: (201.12, 96.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 649)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 571, 1396)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3830)
[M::mem_pestat] mean and std.dev: (706.57, 682.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5047)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 360, 1043)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2617)
[M::mem_pestat] mean and std.dev: (611.51, 554.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3404)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728624 sequences (100000150 bp) in 2.194 CPU sec, 2.240 real sec...
[M::process] read 727928 sequences (100000172 bp) in 1.710 CPU sec, 1.709 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 299969, 38, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 261, 1092)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2930)
[M::mem_pestat] mean and std.dev: (660.51, 781.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3849)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 181, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 519)
[M::mem_pestat] mean and std.dev: (201.45, 96.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 649)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 873, 1799)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4917)
[M::mem_pestat] mean and std.dev: (1197.19, 1202.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6476)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 380, 909)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2231)
[M::mem_pestat] mean and std.dev: (566.62, 439.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2892)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 730422 reads in 158.118 CPU sec, 5.006 real sec
[M::mem_process_seqs] Processed 730308 reads in 108.678 CPU sec, 3.457 real sec
sorting block 166, #reads = 1094624 mem = 536878641 peak = 1177673728
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 299245, 45, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (403, 784, 2538)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6808)
[M::mem_pestat] mean and std.dev: (1290.03, 1327.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8943)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 183, 263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 529)
[M::mem_pestat] mean and std.dev: (203.93, 98.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 662)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 593, 1383)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3669)
[M::mem_pestat] mean and std.dev: (671.18, 627.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4812)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 367, 882)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2198)
[M::mem_pestat] mean and std.dev: (486.24, 345.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2856)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727250 sequences (100000180 bp) in 2.469 CPU sec, 2.505 real sec...
[M::process] read 725954 sequences (100000100 bp) in 1.670 CPU sec, 1.670 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 298747, 42, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 330, 804)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1982)
[M::mem_pestat] mean and std.dev: (474.94, 377.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2571)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 184, 264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 532)
[M::mem_pestat] mean and std.dev: (205.10, 98.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 666)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 760, 1988)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5570)
[M::mem_pestat] mean and std.dev: (832.22, 805.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7361)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 322, 894)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2276)
[M::mem_pestat] mean and std.dev: (430.14, 360.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2967)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 728624 reads in 154.810 CPU sec, 4.892 real sec
[M::mem_process_seqs] Processed 727928 reads in 174.436 CPU sec, 5.533 real sec
sorting block 167, #reads = 1092690 mem = 536882915 peak = 1177673728
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 298426, 42, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 373, 768)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1896)
[M::mem_pestat] mean and std.dev: (416.79, 333.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2460)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 185, 265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 533)
[M::mem_pestat] mean and std.dev: (205.59, 98.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 667)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 596, 1263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3301)
[M::mem_pestat] mean and std.dev: (763.50, 739.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4320)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 315, 719)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1767)
[M::mem_pestat] mean and std.dev: (436.37, 359.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2291)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725684 sequences (100000255 bp) in 2.248 CPU sec, 2.311 real sec...
[M::process] read 725536 sequences (100000257 bp) in 1.660 CPU sec, 1.655 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 297703, 51, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 573, 971)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2443)
[M::mem_pestat] mean and std.dev: (655.36, 489.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3179)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 186, 267)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 537)
[M::mem_pestat] mean and std.dev: (207.34, 99.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 672)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (308, 842, 2286)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6242)
[M::mem_pestat] mean and std.dev: (1167.12, 1127.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8220)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (267, 492, 805)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1881)
[M::mem_pestat] mean and std.dev: (514.29, 363.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2419)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 727250 reads in 157.604 CPU sec, 4.994 real sec
sorting block 168, #reads = 1092831 mem = 536880740 peak = 1177673728
[M::mem_process_seqs] Processed 725954 reads in 111.086 CPU sec, 3.526 real sec
sorting block 169, #reads = 1088786 mem = 536882556 peak = 1177673728
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 298077, 29, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 310, 733)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1773)
[M::mem_pestat] mean and std.dev: (468.96, 416.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2293)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 187, 269)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 543)
[M::mem_pestat] mean and std.dev: (208.46, 100.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 680)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 500, 1750)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4798)
[M::mem_pestat] mean and std.dev: (1075.46, 1132.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6322)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 444, 1206)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3194)
[M::mem_pestat] mean and std.dev: (756.52, 685.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4188)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725092 sequences (100000195 bp) in 2.215 CPU sec, 2.264 real sec...
[M::process] read 724972 sequences (100000148 bp) in 1.740 CPU sec, 1.742 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 298206, 49, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 360, 1098)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2862)
[M::mem_pestat] mean and std.dev: (656.30, 624.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3744)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 186, 267)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 537)
[M::mem_pestat] mean and std.dev: (207.38, 99.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 672)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (253, 498, 1086)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2752)
[M::mem_pestat] mean and std.dev: (623.26, 496.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3585)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 352, 1382)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3720)
[M::mem_pestat] mean and std.dev: (770.48, 877.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4889)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 725684 reads in 153.959 CPU sec, 4.870 real sec
[M::mem_process_seqs] Processed 725536 reads in 103.953 CPU sec, 3.292 real sec
sorting block 170, #reads = 1091495 mem = 536877511 peak = 1177673728
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 297757, 43, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 758, 1154)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2972)
[M::mem_pestat] mean and std.dev: (723.78, 611.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3881)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 187, 269)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 543)
[M::mem_pestat] mean and std.dev: (208.50, 100.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 680)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (337, 633, 1423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3595)
[M::mem_pestat] mean and std.dev: (900.38, 847.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4681)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 298, 600)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1412)
[M::mem_pestat] mean and std.dev: (370.52, 282.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1818)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724698 sequences (100000073 bp) in 2.248 CPU sec, 2.297 real sec...
[M::process] read 723268 sequences (100000264 bp) in 1.640 CPU sec, 1.640 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 297164, 28, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 432, 1293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3419)
[M::mem_pestat] mean and std.dev: (743.53, 733.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4482)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 187, 268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 540)
[M::mem_pestat] mean and std.dev: (208.04, 99.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 676)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 289, 930)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2518)
[M::mem_pestat] mean and std.dev: (454.04, 495.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3312)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (265, 475, 1559)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4147)
[M::mem_pestat] mean and std.dev: (1004.10, 1090.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5441)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 725092 reads in 150.670 CPU sec, 4.769 real sec
sorting block 171, #reads = 1091212 mem = 536876452 peak = 1177673728
[M::mem_process_seqs] Processed 724972 reads in 102.434 CPU sec, 3.243 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 297505, 42, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 644, 1855)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5123)
[M::mem_pestat] mean and std.dev: (831.03, 795.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6757)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 188, 271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 547)
[M::mem_pestat] mean and std.dev: (209.62, 100.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 685)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (430, 975, 1836)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4648)
[M::mem_pestat] mean and std.dev: (1091.88, 766.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6054)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 354, 886)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2238)
[M::mem_pestat] mean and std.dev: (482.07, 449.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2914)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723188 sequences (100000227 bp) in 2.300 CPU sec, 2.324 real sec...
[M::process] read 723248 sequences (100000093 bp) in 1.590 CPU sec, 1.596 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 296877, 53, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 339, 1047)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2849)
[M::mem_pestat] mean and std.dev: (433.54, 400.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3750)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 190, 273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 551)
[M::mem_pestat] mean and std.dev: (211.24, 101.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 690)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (116, 792, 1411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4001)
[M::mem_pestat] mean and std.dev: (818.40, 828.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5296)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 284, 893)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2349)
[M::mem_pestat] mean and std.dev: (537.51, 513.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3077)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724698 reads in 145.708 CPU sec, 4.608 real sec
sorting block 172, #reads = 1092540 mem = 536878692 peak = 1177673728
[M::mem_process_seqs] Processed 723268 reads in 99.907 CPU sec, 3.171 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 296942, 45, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 425, 835)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2055)
[M::mem_pestat] mean and std.dev: (443.79, 341.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2665)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 189, 273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 551)
[M::mem_pestat] mean and std.dev: (211.43, 102.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 690)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (308, 770, 1249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3131)
[M::mem_pestat] mean and std.dev: (697.64, 560.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4072)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 281, 1538)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4182)
[M::mem_pestat] mean and std.dev: (763.80, 989.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5504)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 173, #reads = 1090904 mem = 536878185 peak = 1177673728
[M::process] read 722906 sequences (100000052 bp) in 3.325 CPU sec, 3.448 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 297290, 25, 94)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 341, 844)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2148)
[M::mem_pestat] mean and std.dev: (466.23, 451.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2800)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 189, 273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 551)
[M::mem_pestat] mean and std.dev: (210.91, 101.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 690)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 373, 1329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3655)
[M::mem_pestat] mean and std.dev: (733.12, 792.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4818)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (265, 360, 1098)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2764)
[M::mem_pestat] mean and std.dev: (686.39, 701.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3597)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723248 reads in 155.035 CPU sec, 4.899 real sec
[M::mem_process_seqs] Processed 723188 reads in 174.525 CPU sec, 5.522 real sec
[M::process] read 722826 sequences (100000157 bp) in 2.265 CPU sec, 2.320 real sec...
sorting block 174, #reads = 1091391 mem = 536880841 peak = 1177673728
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 296792, 36, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 382, 1020)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2736)
[M::mem_pestat] mean and std.dev: (562.90, 611.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3594)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 190, 275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 557)
[M::mem_pestat] mean and std.dev: (212.76, 102.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 698)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (476, 949, 2904)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7760)
[M::mem_pestat] mean and std.dev: (1699.61, 1758.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10188)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 334, 702)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1664)
[M::mem_pestat] mean and std.dev: (448.29, 359.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2145)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723186 sequences (100000254 bp) in 2.634 CPU sec, 2.751 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 296988, 50, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 255, 821)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2065)
[M::mem_pestat] mean and std.dev: (420.57, 377.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2687)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 191, 275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 557)
[M::mem_pestat] mean and std.dev: (212.47, 102.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 698)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (346, 661, 1471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3721)
[M::mem_pestat] mean and std.dev: (867.06, 734.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4846)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (287, 534, 814)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1868)
[M::mem_pestat] mean and std.dev: (557.74, 390.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2395)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 722906 reads in 148.526 CPU sec, 4.711 real sec
[M::mem_process_seqs] Processed 722826 reads in 101.503 CPU sec, 3.192 real sec
[M::process] read 723336 sequences (100000179 bp) in 2.101 CPU sec, 2.135 real sec...
sorting block 175, #reads = 1090344 mem = 536878332 peak = 1177673728
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 297220, 45, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 558, 1608)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4458)
[M::mem_pestat] mean and std.dev: (777.25, 791.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5883)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 190, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 554)
[M::mem_pestat] mean and std.dev: (212.04, 102.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 694)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 416, 1223)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3285)
[M::mem_pestat] mean and std.dev: (603.67, 631.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4316)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 341, 1796)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4884)
[M::mem_pestat] mean and std.dev: (801.97, 986.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6428)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723924 sequences (100000199 bp) in 2.524 CPU sec, 2.592 real sec...
[M::process] read 19176 sequences (2617730 bp) in 0.250 CPU sec, 0.248 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 296987, 48, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (267, 628, 1134)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2868)
[M::mem_pestat] mean and std.dev: (748.53, 605.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3735)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 189, 273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 551)
[M::mem_pestat] mean and std.dev: (211.25, 101.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 690)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 299, 848)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2230)
[M::mem_pestat] mean and std.dev: (528.75, 522.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2921)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 294, 701)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1729)
[M::mem_pestat] mean and std.dev: (462.86, 423.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2243)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723186 reads in 145.015 CPU sec, 4.649 real sec
sorting block 176, #reads = 1091696 mem = 536880934 peak = 1177673728
[M::mem_process_seqs] Processed 723336 reads in 99.303 CPU sec, 3.166 real sec
sorting block 177, #reads = 1091397 mem = 536878460 peak = 1236750336
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 297164, 51, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 323, 1461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3987)
[M::mem_pestat] mean and std.dev: (873.90, 926.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5250)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 189, 272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 550)
[M::mem_pestat] mean and std.dev: (210.36, 101.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 689)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (366, 747, 1713)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4407)
[M::mem_pestat] mean and std.dev: (901.59, 783.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5754)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 443, 1128)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2976)
[M::mem_pestat] mean and std.dev: (743.59, 686.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3900)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (1, 7747, 2, 1)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 183, 265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 539)
[M::mem_pestat] mean and std.dev: (204.52, 99.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 676)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_process_seqs] Processed 723924 reads in 87.949 CPU sec, 2.854 real sec
[M::mem_process_seqs] Processed 19176 reads in 21.847 CPU sec, 0.703 real sec
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000c06f2
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: INTEL(R) XEON(R) PLATINUM 8559C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 193850810
overall: 70743777280 mem 32894.255 user 672.930 sys 1119.942 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1136_4Z5-T1-TDNA-1_A23MHWWLT4_1.L002\tPU:L002\tSM:1136_4Z5-T1-TDNA-1_A23MHWWLT4_1\tLB:1136_4Z5-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1136_4Z5-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1136_4Z5-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 1119.987 sec; CPU: 33567.192 sec
sorting block 178, #reads = 959394 mem = 473395725 peak = 1236750336
uniq header count 1
merging 179 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000c06f2
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: INTEL(R) XEON(R) PLATINUM 8559C
threads: 31 max 192
algo: util-sort
license: sentieon:util=1
output file size: 9976142761
output reads: 195628829
bam_mem_sort: 179 calls 121.032 user 3.156 sys 126.719 real
bam_write: 179 calls 116.990 user 7.487 sys 218.410 real
execute: 1 calls 41.161 user 1.639 sys 1179.071 real
merge_files: 1 calls 41.141 user 1.598 sys 57.791 real
parse_chunk: 2863 calls 170.865 user 42.712 sys 252.527 real
read_chunk: 7762 calls 87.604 user 51.567 sys 1067.362 real
sort_block: 1 calls 71.637 user 51.183 sys 1043.310 real
write_chunk: 4897 calls 40.822 user 1.258 sys 56.855 real
overall: 4129386496 mem 2503.035 user 131.370 sys 1179.095 real
ls: cannot access '*.cram': No such file or directory