Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/fc/8d7348aaa519c69066790a8ff686f0/.command.sh
  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta.fai
  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/BWAIndex
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/18/9ff6745e6b6f65ea17553134201944/1136_3WJ-T1-TDNA-1_A23MHWWLT4_1/1136_3WJ-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/18/9ff6745e6b6f65ea17553134201944/1136_3WJ-T1-TDNA-1_A23MHWWLT4_1/1136_3WJ-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/fc/8d7348aaa519c69066790a8ff686f0/.command.run
==> STAGING COMPLETE (7 inputs)

cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1136_3WJ-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 1913.774 CPU sec, 68.683 real sec
[M::process] read 712600 sequences (100000158 bp) in 1.586 CPU sec, 1.590 real sec...
[M::process] read 711448 sequences (100000183 bp) in 1.806 CPU sec, 1.814 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 283512, 31, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (258, 436, 972)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2400)
[M::mem_pestat] mean and std.dev: (533.57, 431.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3114)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 208, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 620)
[M::mem_pestat] mean and std.dev: (231.39, 114.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 779)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (338, 458, 1267)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3125)
[M::mem_pestat] mean and std.dev: (685.17, 699.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4054)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 461, 1129)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2955)
[M::mem_pestat] mean and std.dev: (725.32, 634.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3868)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 710404 sequences (100000012 bp) in 1.833 CPU sec, 1.839 real sec...
[M::process] read 709384 sequences (100000066 bp) in 1.868 CPU sec, 1.888 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (90, 282546, 39, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 343, 1008)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2686)
[M::mem_pestat] mean and std.dev: (511.74, 489.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3525)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 209, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 621)
[M::mem_pestat] mean and std.dev: (232.64, 114.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 780)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (301, 602, 1748)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4642)
[M::mem_pestat] mean and std.dev: (1051.10, 1037.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6089)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 281, 1461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4079)
[M::mem_pestat] mean and std.dev: (713.94, 887.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5388)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 712600 reads in 236.141 CPU sec, 7.500 real sec
[M::mem_process_seqs] Processed 711448 reads in 168.911 CPU sec, 5.449 real sec
sorting block 0, #reads = 1074645 mem = 536881534 peak = 597098496
[M::process] read 708002 sequences (100000006 bp) in 2.884 CPU sec, 3.076 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 282435, 46, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 428, 1019)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2651)
[M::mem_pestat] mean and std.dev: (649.03, 589.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3467)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 212, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 631)
[M::mem_pestat] mean and std.dev: (235.42, 116.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 793)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (352, 688, 1276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3124)
[M::mem_pestat] mean and std.dev: (833.62, 627.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4048)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 344, 908)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2268)
[M::mem_pestat] mean and std.dev: (450.74, 381.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2948)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707114 sequences (100000226 bp) in 2.015 CPU sec, 2.031 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (81, 281996, 36, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 303, 707)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1679)
[M::mem_pestat] mean and std.dev: (392.00, 340.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2165)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 214, 311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 641)
[M::mem_pestat] mean and std.dev: (238.29, 118.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 806)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (470, 636, 1283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2909)
[M::mem_pestat] mean and std.dev: (740.94, 467.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3722)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 399, 885)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2183)
[M::mem_pestat] mean and std.dev: (500.33, 384.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2832)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 281699, 42, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 290, 1167)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3183)
[M::mem_pestat] mean and std.dev: (530.14, 595.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4191)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 216, 314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 648)
[M::mem_pestat] mean and std.dev: (240.50, 119.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 815)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 955, 2860)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8164)
[M::mem_pestat] mean and std.dev: (1323.15, 1323.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10816)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (262, 454, 881)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2119)
[M::mem_pestat] mean and std.dev: (570.42, 463.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2738)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 710404 reads in 331.608 CPU sec, 10.666 real sec
[M::mem_process_seqs] Processed 709384 reads in 261.060 CPU sec, 8.419 real sec
sorting block 1, #reads = 1070982 mem = 536884580 peak = 751239168
[M::mem_process_seqs] Processed 708002 reads in 296.016 CPU sec, 9.580 real sec
[M::process] read 707078 sequences (100000086 bp) in 2.777 CPU sec, 2.944 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 281887, 55, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 247, 620)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1490)
[M::mem_pestat] mean and std.dev: (323.98, 251.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1925)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 218, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 655)
[M::mem_pestat] mean and std.dev: (242.86, 120.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 824)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (391, 1113, 1726)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4396)
[M::mem_pestat] mean and std.dev: (1080.88, 878.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5731)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 540, 1487)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3961)
[M::mem_pestat] mean and std.dev: (724.44, 685.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5198)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 2, #reads = 1070682 mem = 536879349 peak = 751239168
[M::process] read 706760 sequences (100000198 bp) in 2.990 CPU sec, 3.221 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 281048, 48, 92)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 563, 941)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2381)
[M::mem_pestat] mean and std.dev: (554.60, 467.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3101)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 219, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 659)
[M::mem_pestat] mean and std.dev: (243.72, 121.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 829)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (335, 897, 1713)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4469)
[M::mem_pestat] mean and std.dev: (1138.81, 1122.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5847)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 336, 964)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2476)
[M::mem_pestat] mean and std.dev: (525.44, 496.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3232)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707114 reads in 230.726 CPU sec, 7.488 real sec
[M::process] read 706332 sequences (100000115 bp) in 2.643 CPU sec, 2.766 real sec...
sorting block 3, #reads = 1071226 mem = 536879509 peak = 751239168
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (87, 280989, 64, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 293, 1076)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2888)
[M::mem_pestat] mean and std.dev: (564.25, 653.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3794)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 219, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653)
[M::mem_pestat] mean and std.dev: (242.90, 120.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 821)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (493, 1145, 2885)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7669)
[M::mem_pestat] mean and std.dev: (1610.33, 1648.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10061)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 401, 957)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2459)
[M::mem_pestat] mean and std.dev: (495.06, 409.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3210)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706410 sequences (100000130 bp) in 2.437 CPU sec, 2.443 real sec...
[M::mem_process_seqs] Processed 706760 reads in 134.122 CPU sec, 4.297 real sec
[M::mem_process_seqs] Processed 707078 reads in 367.729 CPU sec, 11.859 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (86, 281116, 56, 103)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (259, 427, 1007)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2503)
[M::mem_pestat] mean and std.dev: (673.25, 614.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3251)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 219, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 651)
[M::mem_pestat] mean and std.dev: (242.70, 119.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 818)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (363, 782, 1852)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4830)
[M::mem_pestat] mean and std.dev: (1121.45, 1221.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6319)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 471, 1452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3862)
[M::mem_pestat] mean and std.dev: (813.60, 887.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5067)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 4, #reads = 1069635 mem = 536879467 peak = 751239168
[M::process] read 706132 sequences (100000234 bp) in 3.231 CPU sec, 3.615 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 280730, 47, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 413, 1703)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4729)
[M::mem_pestat] mean and std.dev: (877.31, 1008.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6242)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 218, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 650)
[M::mem_pestat] mean and std.dev: (242.32, 119.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 817)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (493, 669, 1510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3544)
[M::mem_pestat] mean and std.dev: (826.59, 625.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4561)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 386, 1245)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3309)
[M::mem_pestat] mean and std.dev: (632.03, 636.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4341)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706332 reads in 267.036 CPU sec, 8.612 real sec
[M::mem_process_seqs] Processed 706410 reads in 169.684 CPU sec, 5.433 real sec
[M::process] read 705982 sequences (100000043 bp) in 2.584 CPU sec, 2.732 real sec...
sorting block 5, #reads = 1069402 mem = 536880169 peak = 751239168
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 280863, 39, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 476, 1434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3894)
[M::mem_pestat] mean and std.dev: (734.71, 685.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5124)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 218, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 645)
[M::mem_pestat] mean and std.dev: (241.89, 118.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 810)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (100, 664, 2779)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8137)
[M::mem_pestat] mean and std.dev: (1306.64, 1507.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10816)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 421, 1228)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3242)
[M::mem_pestat] mean and std.dev: (654.11, 608.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4249)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705398 sequences (100000204 bp) in 3.151 CPU sec, 3.437 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 280901, 54, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 497, 996)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2520)
[M::mem_pestat] mean and std.dev: (620.77, 571.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3282)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 219, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 651)
[M::mem_pestat] mean and std.dev: (243.18, 119.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 818)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (373, 754, 1716)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4402)
[M::mem_pestat] mean and std.dev: (1122.47, 1012.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5745)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 466, 964)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2406)
[M::mem_pestat] mean and std.dev: (555.00, 489.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3127)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706132 reads in 231.064 CPU sec, 7.427 real sec
[M::process] read 704974 sequences (100000065 bp) in 2.376 CPU sec, 2.413 real sec...
sorting block 6, #reads = 1070183 mem = 536878715 peak = 757493760
[M::mem_process_seqs] Processed 705982 reads in 170.050 CPU sec, 5.433 real sec
[M::process] read 704628 sequences (100000004 bp) in 2.964 CPU sec, 3.355 real sec...
sorting block 7, #reads = 1070032 mem = 536878499 peak = 783917056
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 280088, 46, 84)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 335, 869)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2247)
[M::mem_pestat] mean and std.dev: (483.38, 461.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2936)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 222, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (245.62, 121.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 831)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (293, 647, 1325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3389)
[M::mem_pestat] mean and std.dev: (782.89, 646.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4421)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (308, 615, 2290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6254)
[M::mem_pestat] mean and std.dev: (1203.41, 1295.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8236)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704304 sequences (100000022 bp) in 2.382 CPU sec, 2.404 real sec...
[M::mem_process_seqs] Processed 704974 reads in 136.686 CPU sec, 4.348 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 280737, 49, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 519, 1223)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3195)
[M::mem_pestat] mean and std.dev: (698.97, 642.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4181)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 221, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 655)
[M::mem_pestat] mean and std.dev: (244.81, 120.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 823)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (380, 700, 1949)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5087)
[M::mem_pestat] mean and std.dev: (1103.43, 1040.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6656)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 327, 772)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1896)
[M::mem_pestat] mean and std.dev: (352.10, 284.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2458)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 280199, 50, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (252, 436, 829)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1983)
[M::mem_pestat] mean and std.dev: (481.58, 339.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2560)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 222, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 662)
[M::mem_pestat] mean and std.dev: (246.44, 121.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 832)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (414, 965, 1419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3429)
[M::mem_pestat] mean and std.dev: (1005.00, 836.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4434)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 679, 1832)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5056)
[M::mem_pestat] mean and std.dev: (929.43, 955.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6668)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705398 reads in 364.128 CPU sec, 11.728 real sec
[M::process] read 704296 sequences (100000010 bp) in 2.795 CPU sec, 2.815 real sec...
sorting block 8, #reads = 1068169 mem = 536882864 peak = 783917056
[M::mem_process_seqs] Processed 704628 reads in 203.218 CPU sec, 6.554 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (85, 280411, 52, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 486, 1022)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2566)
[M::mem_pestat] mean and std.dev: (555.64, 406.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3338)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (247.93, 122.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 844)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 871, 1763)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4777)
[M::mem_pestat] mean and std.dev: (991.68, 1032.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6284)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 425, 1142)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2934)
[M::mem_pestat] mean and std.dev: (560.77, 480.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3830)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706828 sequences (100000125 bp) in 3.865 CPU sec, 4.179 real sec...
sorting block 9, #reads = 1068272 mem = 536887159 peak = 798121984
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 280047, 48, 87)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 340, 615)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1509)
[M::mem_pestat] mean and std.dev: (370.09, 293.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1956)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (248.88, 123.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 848)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (295, 628, 1335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3415)
[M::mem_pestat] mean and std.dev: (766.07, 620.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4455)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 470, 977)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2447)
[M::mem_pestat] mean and std.dev: (650.37, 529.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3182)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704304 reads in 230.007 CPU sec, 7.585 real sec
[M::process] read 711954 sequences (100000077 bp) in 2.290 CPU sec, 2.436 real sec...
[M::mem_process_seqs] Processed 704296 reads in 165.302 CPU sec, 5.514 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (85, 281396, 49, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (313, 585, 939)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2191)
[M::mem_pestat] mean and std.dev: (606.87, 473.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2817)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 220, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 662)
[M::mem_pestat] mean and std.dev: (244.44, 121.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 833)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (411, 912, 1482)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3624)
[M::mem_pestat] mean and std.dev: (870.87, 632.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4695)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (338, 438, 1260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3104)
[M::mem_pestat] mean and std.dev: (631.08, 556.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4026)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 10, #reads = 1068897 mem = 536888413 peak = 798121984
[M::process] read 711662 sequences (100000006 bp) in 3.351 CPU sec, 3.640 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 283867, 52, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 361, 1469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3999)
[M::mem_pestat] mean and std.dev: (644.32, 693.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5264)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 209, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 626)
[M::mem_pestat] mean and std.dev: (233.15, 115.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 787)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 483, 859)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2267)
[M::mem_pestat] mean and std.dev: (520.14, 439.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2971)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (270, 426, 1212)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3096)
[M::mem_pestat] mean and std.dev: (698.17, 664.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4038)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706828 reads in 233.636 CPU sec, 7.556 real sec
[M::process] read 710906 sequences (100000020 bp) in 2.636 CPU sec, 2.775 real sec...
[M::mem_process_seqs] Processed 711954 reads in 166.970 CPU sec, 5.391 real sec
sorting block 11, #reads = 1068974 mem = 536880360 peak = 798121984
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 282992, 35, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 552, 1202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3186)
[M::mem_pestat] mean and std.dev: (699.72, 704.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4178)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 210, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 633)
[M::mem_pestat] mean and std.dev: (235.05, 117.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 796)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (285, 899, 2096)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5718)
[M::mem_pestat] mean and std.dev: (1227.79, 1137.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7529)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (260, 491, 1109)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2807)
[M::mem_pestat] mean and std.dev: (645.33, 714.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3656)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 709912 sequences (100000002 bp) in 3.789 CPU sec, 4.260 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 282360, 45, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 620, 1248)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3310)
[M::mem_pestat] mean and std.dev: (700.56, 632.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4341)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 212, 308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 636)
[M::mem_pestat] mean and std.dev: (236.12, 117.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 800)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (372, 965, 2092)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5532)
[M::mem_pestat] mean and std.dev: (1294.86, 1286.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7252)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 482, 984)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2464)
[M::mem_pestat] mean and std.dev: (559.29, 404.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3204)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 711662 reads in 228.832 CPU sec, 7.459 real sec
[M::mem_process_seqs] Processed 710906 reads in 166.027 CPU sec, 5.340 real sec
[M::process] read 708492 sequences (100000266 bp) in 2.843 CPU sec, 2.965 real sec...
sorting block 12, #reads = 1075166 mem = 536880060 peak = 798121984
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (90, 282637, 44, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 609, 1525)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4153)
[M::mem_pestat] mean and std.dev: (825.52, 784.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5467)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 214, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 646)
[M::mem_pestat] mean and std.dev: (238.82, 119.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 813)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (425, 1121, 2589)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6917)
[M::mem_pestat] mean and std.dev: (1327.64, 1132.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9081)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 341, 854)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2140)
[M::mem_pestat] mean and std.dev: (466.68, 430.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2783)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708144 sequences (100000108 bp) in 3.477 CPU sec, 3.870 real sec...
sorting block 13, #reads = 1074907 mem = 536879730 peak = 828346368
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 282331, 46, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 440, 1307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3431)
[M::mem_pestat] mean and std.dev: (648.70, 583.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4493)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 216, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 657)
[M::mem_pestat] mean and std.dev: (241.65, 120.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 827)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 599, 788)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2018)
[M::mem_pestat] mean and std.dev: (486.37, 333.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2633)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 315, 978)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2492)
[M::mem_pestat] mean and std.dev: (606.66, 564.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3249)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 709912 reads in 226.561 CPU sec, 7.378 real sec
[M::mem_process_seqs] Processed 708492 reads in 164.598 CPU sec, 5.305 real sec
[M::process] read 707724 sequences (100000147 bp) in 3.039 CPU sec, 3.182 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 281725, 46, 90)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 384, 1146)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3052)
[M::mem_pestat] mean and std.dev: (626.45, 636.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4005)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 217, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 660)
[M::mem_pestat] mean and std.dev: (242.73, 121.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 831)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (272, 780, 1321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3419)
[M::mem_pestat] mean and std.dev: (842.69, 740.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4468)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (267, 374, 1427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3747)
[M::mem_pestat] mean and std.dev: (707.25, 701.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4907)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 14, #reads = 1074077 mem = 536879094 peak = 828346368
[M::process] read 707220 sequences (100000130 bp) in 3.679 CPU sec, 4.054 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (87, 281483, 54, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 333, 868)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2180)
[M::mem_pestat] mean and std.dev: (449.60, 405.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2836)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 218, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (243.59, 122.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 832)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 725, 1097)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2763)
[M::mem_pestat] mean and std.dev: (688.16, 462.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3596)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 654, 1215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3187)
[M::mem_pestat] mean and std.dev: (768.76, 752.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4173)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 708144 reads in 230.359 CPU sec, 7.535 real sec
[M::mem_process_seqs] Processed 707724 reads in 167.664 CPU sec, 5.453 real sec
[M::process] read 707226 sequences (100000130 bp) in 3.354 CPU sec, 3.601 real sec...
sorting block 15, #reads = 1072965 mem = 536879388 peak = 828346368
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (90, 281760, 48, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 479, 1505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4107)
[M::mem_pestat] mean and std.dev: (825.72, 796.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5408)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 218, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 658)
[M::mem_pestat] mean and std.dev: (243.15, 121.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 828)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (366, 755, 1291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3141)
[M::mem_pestat] mean and std.dev: (718.77, 581.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4066)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 284, 777)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1961)
[M::mem_pestat] mean and std.dev: (416.91, 364.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2553)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707148 sequences (100000003 bp) in 3.226 CPU sec, 3.593 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 281635, 31, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 267, 856)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2204)
[M::mem_pestat] mean and std.dev: (476.74, 480.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2878)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 218, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 656)
[M::mem_pestat] mean and std.dev: (243.24, 121.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 825)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (322, 515, 556)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1024)
[M::mem_pestat] mean and std.dev: (375.59, 246.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1360)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 469, 754)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1818)
[M::mem_pestat] mean and std.dev: (477.10, 338.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2350)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707220 reads in 232.595 CPU sec, 7.514 real sec
[M::mem_process_seqs] Processed 707226 reads in 168.744 CPU sec, 5.405 real sec
[M::process] read 707256 sequences (100000118 bp) in 3.123 CPU sec, 3.319 real sec...
sorting block 16, #reads = 1071759 mem = 536884236 peak = 828346368
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 281366, 48, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 287, 627)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1483)
[M::mem_pestat] mean and std.dev: (333.94, 205.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1911)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 217, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 643)
[M::mem_pestat] mean and std.dev: (240.27, 118.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 808)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 545, 1034)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2718)
[M::mem_pestat] mean and std.dev: (560.36, 516.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3560)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 335, 671)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1645)
[M::mem_pestat] mean and std.dev: (404.84, 303.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2132)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 17, #reads = 1071266 mem = 536878287 peak = 865288192
[M::process] read 706446 sequences (100000139 bp) in 3.700 CPU sec, 4.214 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 281261, 56, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 311, 1148)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3072)
[M::mem_pestat] mean and std.dev: (708.86, 794.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4034)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 217, 314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 646)
[M::mem_pestat] mean and std.dev: (240.48, 118.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 812)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (309, 948, 1862)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4968)
[M::mem_pestat] mean and std.dev: (1165.31, 1246.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6521)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 558, 1427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3807)
[M::mem_pestat] mean and std.dev: (830.62, 736.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4997)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707148 reads in 235.015 CPU sec, 7.645 real sec
[M::process] read 706238 sequences (100000107 bp) in 2.632 CPU sec, 2.689 real sec...
[M::mem_process_seqs] Processed 707256 reads in 173.066 CPU sec, 5.594 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 280863, 63, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 303, 816)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2040)
[M::mem_pestat] mean and std.dev: (469.51, 397.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2652)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 218, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 650)
[M::mem_pestat] mean and std.dev: (241.73, 118.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 817)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (384, 970, 2215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5877)
[M::mem_pestat] mean and std.dev: (1327.53, 1256.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7708)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 312, 812)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2038)
[M::mem_pestat] mean and std.dev: (484.49, 446.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2651)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 18, #reads = 1070674 mem = 536878802 peak = 865288192
[M::process] read 705804 sequences (100000190 bp) in 3.310 CPU sec, 3.710 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 281091, 42, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 280, 737)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1887)
[M::mem_pestat] mean and std.dev: (384.49, 337.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2462)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 219, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 647)
[M::mem_pestat] mean and std.dev: (242.05, 118.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 813)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (436, 1219, 1699)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4225)
[M::mem_pestat] mean and std.dev: (1264.51, 970.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5488)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (290, 644, 1389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3587)
[M::mem_pestat] mean and std.dev: (940.99, 803.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4686)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706446 reads in 232.898 CPU sec, 7.532 real sec
[M::process] read 705708 sequences (100000234 bp) in 2.762 CPU sec, 2.869 real sec...
[M::mem_process_seqs] Processed 706238 reads in 168.489 CPU sec, 5.427 real sec
sorting block 19, #reads = 1070235 mem = 536887821 peak = 865288192
[M::process] read 705092 sequences (100000277 bp) in 3.598 CPU sec, 3.990 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (111, 280920, 46, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 523, 1027)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2677)
[M::mem_pestat] mean and std.dev: (641.46, 552.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3502)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 221, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 660)
[M::mem_pestat] mean and std.dev: (244.95, 121.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 830)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 791, 1268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3324)
[M::mem_pestat] mean and std.dev: (795.31, 678.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4352)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (264, 384, 938)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2286)
[M::mem_pestat] mean and std.dev: (535.56, 462.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2960)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705708 reads in 136.004 CPU sec, 4.323 real sec
[M::process] read 705744 sequences (100000297 bp) in 2.778 CPU sec, 2.967 real sec...
sorting block 20, #reads = 1070490 mem = 536878084 peak = 865288192
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 280714, 70, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 279, 534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1252)
[M::mem_pestat] mean and std.dev: (354.55, 269.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1611)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 220, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 657)
[M::mem_pestat] mean and std.dev: (243.97, 120.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 826)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 617, 859)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2303)
[M::mem_pestat] mean and std.dev: (513.17, 416.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3025)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 304, 848)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2148)
[M::mem_pestat] mean and std.dev: (482.73, 423.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2798)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (79, 280499, 45, 93)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 294, 748)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1856)
[M::mem_pestat] mean and std.dev: (427.26, 396.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2410)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 222, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (246.01, 121.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 835)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (450, 722, 1187)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2661)
[M::mem_pestat] mean and std.dev: (818.09, 549.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3398)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 303, 841)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2109)
[M::mem_pestat] mean and std.dev: (507.41, 461.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2743)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705804 reads in 368.346 CPU sec, 11.905 real sec
[M::mem_process_seqs] Processed 705092 reads in 205.331 CPU sec, 6.586 real sec
[M::process] read 709800 sequences (100000150 bp) in 2.756 CPU sec, 2.984 real sec...
sorting block 21, #reads = 1069329 mem = 536885912 peak = 865288192
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 280722, 36, 91)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 386, 899)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2315)
[M::mem_pestat] mean and std.dev: (547.17, 414.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3023)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 221, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (245.92, 122.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 838)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (257, 680, 2335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6491)
[M::mem_pestat] mean and std.dev: (1315.06, 1406.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8569)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 560, 1161)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2973)
[M::mem_pestat] mean and std.dev: (702.29, 548.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3879)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 713542 sequences (100000290 bp) in 3.719 CPU sec, 4.262 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (84, 282076, 31, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 396, 1095)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2879)
[M::mem_pestat] mean and std.dev: (579.71, 561.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3771)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 213, 311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 643)
[M::mem_pestat] mean and std.dev: (238.14, 119.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 809)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 851, 2559)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7397)
[M::mem_pestat] mean and std.dev: (1285.33, 1382.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9816)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 470, 1385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3653)
[M::mem_pestat] mean and std.dev: (623.64, 584.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4787)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705744 reads in 238.064 CPU sec, 7.752 real sec
[M::process] read 713278 sequences (100000222 bp) in 2.552 CPU sec, 2.620 real sec...
[M::mem_process_seqs] Processed 709800 reads in 171.966 CPU sec, 5.601 real sec
sorting block 22, #reads = 1069085 mem = 536880112 peak = 865288192
sorting block 23, #reads = 1069767 mem = 536884480 peak = 865288192
[M::process] read 710990 sequences (100000038 bp) in 3.593 CPU sec, 4.034 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 283708, 31, 90)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 509, 1734)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4738)
[M::mem_pestat] mean and std.dev: (1109.83, 1331.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6436)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 208, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 625)
[M::mem_pestat] mean and std.dev: (232.18, 115.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 786)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (361, 517, 1104)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2590)
[M::mem_pestat] mean and std.dev: (647.80, 505.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3333)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (289, 557, 917)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2173)
[M::mem_pestat] mean and std.dev: (629.62, 417.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2801)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 713278 reads in 135.888 CPU sec, 4.384 real sec
[M::process] read 709632 sequences (100000170 bp) in 2.836 CPU sec, 2.929 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 283328, 53, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 334, 905)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2325)
[M::mem_pestat] mean and std.dev: (447.72, 400.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3035)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (141, 206, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 621)
[M::mem_pestat] mean and std.dev: (230.87, 115.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 781)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 592, 1345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3535)
[M::mem_pestat] mean and std.dev: (767.63, 718.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4630)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 408, 978)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2540)
[M::mem_pestat] mean and std.dev: (614.82, 616.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3321)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 283123, 59, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 355, 941)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2395)
[M::mem_pestat] mean and std.dev: (560.86, 497.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3122)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 211, 308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 636)
[M::mem_pestat] mean and std.dev: (235.50, 116.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 800)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (322, 636, 1571)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4069)
[M::mem_pestat] mean and std.dev: (792.12, 713.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5318)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 397, 1335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3533)
[M::mem_pestat] mean and std.dev: (718.08, 711.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4632)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 713542 reads in 365.733 CPU sec, 11.848 real sec
[M::process] read 708292 sequences (100000159 bp) in 3.276 CPU sec, 3.472 real sec...
[M::mem_process_seqs] Processed 710990 reads in 207.883 CPU sec, 6.697 real sec
sorting block 24, #reads = 1075142 mem = 536881719 peak = 865288192
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 282462, 65, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 306, 856)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2196)
[M::mem_pestat] mean and std.dev: (490.64, 435.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2866)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 213, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 644)
[M::mem_pestat] mean and std.dev: (237.93, 117.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 810)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (114, 540, 1914)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5514)
[M::mem_pestat] mean and std.dev: (1110.94, 1343.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7314)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 369, 2028)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5652)
[M::mem_pestat] mean and std.dev: (1062.49, 1347.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7464)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707576 sequences (100000153 bp) in 3.440 CPU sec, 3.777 real sec...
sorting block 25, #reads = 1074387 mem = 536879665 peak = 865386496
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 281826, 51, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 282, 619)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1451)
[M::mem_pestat] mean and std.dev: (355.87, 251.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1867)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 216, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 651)
[M::mem_pestat] mean and std.dev: (240.81, 119.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 819)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (246, 708, 2211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6141)
[M::mem_pestat] mean and std.dev: (1049.44, 1140.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8106)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 323, 956)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2440)
[M::mem_pestat] mean and std.dev: (560.96, 545.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3182)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 709632 reads in 234.996 CPU sec, 7.692 real sec
[M::process] read 707680 sequences (100000298 bp) in 2.766 CPU sec, 2.833 real sec...
[M::mem_process_seqs] Processed 708292 reads in 169.211 CPU sec, 5.498 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 281305, 53, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 369, 866)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2182)
[M::mem_pestat] mean and std.dev: (497.17, 426.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2840)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 218, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 655)
[M::mem_pestat] mean and std.dev: (242.35, 120.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 824)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (374, 776, 1347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3293)
[M::mem_pestat] mean and std.dev: (946.92, 747.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4266)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (268, 375, 943)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2293)
[M::mem_pestat] mean and std.dev: (514.07, 453.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2968)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 26, #reads = 1072486 mem = 536876175 peak = 865386496
[M::process] read 706848 sequences (100000144 bp) in 3.243 CPU sec, 3.606 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 280820, 52, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 329, 593)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1381)
[M::mem_pestat] mean and std.dev: (345.32, 234.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1775)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 218, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 655)
[M::mem_pestat] mean and std.dev: (242.40, 120.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 824)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 548, 1496)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4136)
[M::mem_pestat] mean and std.dev: (842.90, 936.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5456)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 404, 931)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2463)
[M::mem_pestat] mean and std.dev: (482.57, 427.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3229)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707576 reads in 235.333 CPU sec, 7.624 real sec
[M::process] read 707038 sequences (100000028 bp) in 3.041 CPU sec, 3.132 real sec...
[M::mem_process_seqs] Processed 707680 reads in 170.835 CPU sec, 5.471 real sec
sorting block 27, #reads = 1072381 mem = 536881436 peak = 865386496
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (92, 281183, 47, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 407, 1770)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4850)
[M::mem_pestat] mean and std.dev: (941.56, 1032.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6390)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 220, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 662)
[M::mem_pestat] mean and std.dev: (244.32, 121.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 833)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 733, 1217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3259)
[M::mem_pestat] mean and std.dev: (647.80, 524.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4280)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 383, 932)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2332)
[M::mem_pestat] mean and std.dev: (622.63, 591.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3032)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706894 sequences (100000261 bp) in 3.335 CPU sec, 3.869 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 281279, 45, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 531, 1153)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2917)
[M::mem_pestat] mean and std.dev: (647.22, 510.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3799)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 217, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 647)
[M::mem_pestat] mean and std.dev: (241.55, 119.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 813)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 438, 1128)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3032)
[M::mem_pestat] mean and std.dev: (617.09, 612.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3984)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 441, 811)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1943)
[M::mem_pestat] mean and std.dev: (514.76, 371.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2509)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706848 reads in 233.344 CPU sec, 7.549 real sec
[M::process] read 706636 sequences (100000200 bp) in 2.510 CPU sec, 2.661 real sec...
[M::mem_process_seqs] Processed 707038 reads in 168.821 CPU sec, 5.394 real sec
sorting block 28, #reads = 1071105 mem = 536883357 peak = 865386496
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 281281, 53, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 543, 1121)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2917)
[M::mem_pestat] mean and std.dev: (630.85, 537.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3815)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 218, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 650)
[M::mem_pestat] mean and std.dev: (241.92, 119.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 817)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (281, 736, 1357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3509)
[M::mem_pestat] mean and std.dev: (1047.50, 1014.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5105)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 406, 1490)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3974)
[M::mem_pestat] mean and std.dev: (724.74, 759.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5216)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706398 sequences (100000096 bp) in 3.468 CPU sec, 3.837 real sec...
sorting block 29, #reads = 1071127 mem = 536881652 peak = 881737728
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 280425, 38, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 366, 797)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2049)
[M::mem_pestat] mean and std.dev: (459.73, 461.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2675)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 218, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 647)
[M::mem_pestat] mean and std.dev: (241.52, 118.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 813)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 545, 1101)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2997)
[M::mem_pestat] mean and std.dev: (708.53, 636.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3945)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 326, 836)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2116)
[M::mem_pestat] mean and std.dev: (519.41, 473.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2756)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705888 sequences (100000051 bp) in 2.582 CPU sec, 2.608 real sec...
[M::mem_process_seqs] Processed 706894 reads in 238.183 CPU sec, 7.666 real sec
[M::mem_process_seqs] Processed 706636 reads in 171.479 CPU sec, 5.485 real sec
sorting block 30, #reads = 1069875 mem = 536881630 peak = 881737728
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 280866, 40, 85)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 362, 1001)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2619)
[M::mem_pestat] mean and std.dev: (530.96, 518.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3428)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 218, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 650)
[M::mem_pestat] mean and std.dev: (242.18, 119.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 817)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (369, 548, 1232)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2958)
[M::mem_pestat] mean and std.dev: (655.72, 516.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3821)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 329, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 990)
[M::mem_pestat] mean and std.dev: (300.32, 126.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1249)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706320 sequences (100000021 bp) in 3.312 CPU sec, 3.674 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (87, 280728, 36, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 339, 916)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2280)
[M::mem_pestat] mean and std.dev: (511.44, 457.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2962)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 219, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 651)
[M::mem_pestat] mean and std.dev: (242.70, 118.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 818)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 660, 1994)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5526)
[M::mem_pestat] mean and std.dev: (993.17, 895.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7292)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 412, 1281)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3419)
[M::mem_pestat] mean and std.dev: (663.93, 630.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4488)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705928 sequences (100000233 bp) in 2.743 CPU sec, 2.817 real sec...
[M::mem_process_seqs] Processed 706398 reads in 239.132 CPU sec, 7.679 real sec
[M::mem_process_seqs] Processed 705888 reads in 173.429 CPU sec, 5.555 real sec
sorting block 31, #reads = 1068179 mem = 536878604 peak = 881737728
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 281079, 61, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 454, 1248)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3278)
[M::mem_pestat] mean and std.dev: (722.91, 678.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4293)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 219, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 656)
[M::mem_pestat] mean and std.dev: (243.62, 120.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 825)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (470, 938, 1593)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3839)
[M::mem_pestat] mean and std.dev: (960.45, 895.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4962)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 614, 1409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3733)
[M::mem_pestat] mean and std.dev: (759.88, 679.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4895)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705746 sequences (100000029 bp) in 3.419 CPU sec, 3.819 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 280492, 40, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 370, 1359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3645)
[M::mem_pestat] mean and std.dev: (578.37, 572.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4788)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 219, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 657)
[M::mem_pestat] mean and std.dev: (244.16, 121.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 826)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (480, 658, 1300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2940)
[M::mem_pestat] mean and std.dev: (745.03, 490.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3760)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 497, 993)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2487)
[M::mem_pestat] mean and std.dev: (584.20, 429.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3234)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706184 sequences (100000143 bp) in 2.759 CPU sec, 2.768 real sec...
[M::mem_process_seqs] Processed 706320 reads in 242.241 CPU sec, 8.101 real sec
[M::mem_process_seqs] Processed 705928 reads in 171.754 CPU sec, 5.503 real sec
sorting block 32, #reads = 1068309 mem = 536888764 peak = 881737728
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (86, 280489, 37, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 426, 1729)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4703)
[M::mem_pestat] mean and std.dev: (1028.38, 1087.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6190)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 219, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 651)
[M::mem_pestat] mean and std.dev: (243.42, 120.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 818)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (106, 531, 874)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2410)
[M::mem_pestat] mean and std.dev: (496.21, 448.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3178)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 262, 559)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1277)
[M::mem_pestat] mean and std.dev: (360.44, 274.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1636)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 33, #reads = 1068122 mem = 536880467 peak = 890933248
[M::process] read 712442 sequences (100000269 bp) in 3.517 CPU sec, 3.816 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (93, 280799, 33, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 439, 760)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1904)
[M::mem_pestat] mean and std.dev: (414.09, 360.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2476)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 219, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 654)
[M::mem_pestat] mean and std.dev: (243.45, 120.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 822)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (249, 617, 1325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3477)
[M::mem_pestat] mean and std.dev: (713.55, 646.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4553)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 423, 953)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2457)
[M::mem_pestat] mean and std.dev: (540.36, 548.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3209)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 712202 sequences (100000236 bp) in 2.629 CPU sec, 2.693 real sec...
[M::mem_process_seqs] Processed 705746 reads in 240.352 CPU sec, 7.760 real sec
[M::mem_process_seqs] Processed 706184 reads in 176.457 CPU sec, 5.681 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 283303, 31, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 289, 967)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2593)
[M::mem_pestat] mean and std.dev: (465.96, 458.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3406)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
sorting block 34, #reads = 1067874 mem = 536885106 peak = 890933248
[M::mem_pestat] (25, 50, 75) percentile: (143, 208, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 626)
[M::mem_pestat] mean and std.dev: (232.69, 115.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 787)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (832, 1204, 2081)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4579)
[M::mem_pestat] mean and std.dev: (982.96, 449.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5828)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 392, 1143)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2997)
[M::mem_pestat] mean and std.dev: (578.49, 559.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3924)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 711472 sequences (100000068 bp) in 3.533 CPU sec, 4.005 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (88, 283233, 39, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 417, 922)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2314)
[M::mem_pestat] mean and std.dev: (511.02, 408.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3010)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 209, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 629)
[M::mem_pestat] mean and std.dev: (233.32, 116.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 791)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (529, 1030, 2127)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5323)
[M::mem_pestat] mean and std.dev: (1162.78, 1014.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6921)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 378, 1348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3614)
[M::mem_pestat] mean and std.dev: (746.40, 759.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4747)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 712442 reads in 232.361 CPU sec, 7.523 real sec
[M::process] read 710424 sequences (100000165 bp) in 2.644 CPU sec, 2.727 real sec...
[M::mem_process_seqs] Processed 712202 reads in 167.791 CPU sec, 5.414 real sec
sorting block 35, #reads = 1070973 mem = 536882402 peak = 890933248
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 282612, 31, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 332, 502)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1166)
[M::mem_pestat] mean and std.dev: (323.56, 187.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1498)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 211, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 633)
[M::mem_pestat] mean and std.dev: (234.91, 116.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 796)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 681, 1717)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4823)
[M::mem_pestat] mean and std.dev: (858.11, 899.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6376)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 433, 1345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3555)
[M::mem_pestat] mean and std.dev: (820.04, 757.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4660)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 709398 sequences (100000061 bp) in 3.251 CPU sec, 3.625 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (89, 283053, 58, 102)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 489, 1125)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2911)
[M::mem_pestat] mean and std.dev: (698.69, 621.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3804)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 212, 310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 640)
[M::mem_pestat] mean and std.dev: (237.13, 118.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 805)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (342, 765, 2395)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6501)
[M::mem_pestat] mean and std.dev: (1386.77, 1470.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8554)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 552, 1185)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3145)
[M::mem_pestat] mean and std.dev: (612.65, 571.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4125)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708398 sequences (100000179 bp) in 2.531 CPU sec, 2.594 real sec...
[M::mem_process_seqs] Processed 711472 reads in 236.323 CPU sec, 7.981 real sec
[M::mem_process_seqs] Processed 710424 reads in 168.437 CPU sec, 5.421 real sec
sorting block 36, #reads = 1074458 mem = 536882505 peak = 890933248
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (81, 282306, 52, 90)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 281, 585)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1391)
[M::mem_pestat] mean and std.dev: (356.44, 273.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1794)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 214, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 644)
[M::mem_pestat] mean and std.dev: (238.66, 118.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 810)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (443, 744, 1297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3005)
[M::mem_pestat] mean and std.dev: (853.10, 692.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3859)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (264, 645, 2084)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5724)
[M::mem_pestat] mean and std.dev: (1032.88, 1145.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7544)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707936 sequences (100000215 bp) in 3.492 CPU sec, 3.847 real sec...
sorting block 37, #reads = 1074221 mem = 536877454 peak = 905216000
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 281787, 57, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 344, 1305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3507)
[M::mem_pestat] mean and std.dev: (686.23, 709.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4608)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 216, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 654)
[M::mem_pestat] mean and std.dev: (241.47, 120.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 823)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (306, 1080, 2541)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7011)
[M::mem_pestat] mean and std.dev: (1427.93, 1468.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9246)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 438, 972)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2518)
[M::mem_pestat] mean and std.dev: (589.09, 474.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3291)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 709398 reads in 230.121 CPU sec, 7.437 real sec
[M::mem_process_seqs] Processed 708398 reads in 166.393 CPU sec, 5.346 real sec
[M::process] read 707696 sequences (100000078 bp) in 3.176 CPU sec, 3.330 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 281809, 47, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 297, 587)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1285)
[M::mem_pestat] mean and std.dev: (401.31, 292.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1634)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 217, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 655)
[M::mem_pestat] mean and std.dev: (242.14, 120.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 824)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (574, 1149, 1468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3256)
[M::mem_pestat] mean and std.dev: (867.92, 531.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4150)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 394, 1378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3672)
[M::mem_pestat] mean and std.dev: (760.13, 769.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4819)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 38, #reads = 1071066 mem = 536882091 peak = 905216000
[M::process] read 707814 sequences (100000049 bp) in 3.374 CPU sec, 3.839 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 281263, 46, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 509, 1128)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2900)
[M::mem_pestat] mean and std.dev: (680.78, 527.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3786)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 218, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 655)
[M::mem_pestat] mean and std.dev: (242.77, 120.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 824)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (346, 951, 1723)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4477)
[M::mem_pestat] mean and std.dev: (1069.24, 1024.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5854)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 394, 1161)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2975)
[M::mem_pestat] mean and std.dev: (662.48, 680.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3882)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707936 reads in 230.571 CPU sec, 7.442 real sec
[M::process] read 709306 sequences (100000203 bp) in 2.798 CPU sec, 2.868 real sec...
[M::mem_process_seqs] Processed 707696 reads in 170.237 CPU sec, 5.413 real sec
sorting block 39, #reads = 1070324 mem = 536878487 peak = 905216000
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (95, 281758, 52, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 398, 804)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1960)
[M::mem_pestat] mean and std.dev: (464.80, 356.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2538)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 216, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 654)
[M::mem_pestat] mean and std.dev: (241.77, 120.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 823)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (338, 717, 1605)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4139)
[M::mem_pestat] mean and std.dev: (1069.69, 1079.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5406)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (266, 464, 1181)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3011)
[M::mem_pestat] mean and std.dev: (708.08, 579.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3926)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707894 sequences (100000247 bp) in 3.728 CPU sec, 4.554 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 282070, 47, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 568, 1279)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3479)
[M::mem_pestat] mean and std.dev: (673.15, 626.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4579)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 212, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 629)
[M::mem_pestat] mean and std.dev: (235.83, 116.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 790)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 529, 1139)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3105)
[M::mem_pestat] mean and std.dev: (719.61, 745.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4088)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 459, 1276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3412)
[M::mem_pestat] mean and std.dev: (767.94, 740.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4480)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707814 reads in 234.658 CPU sec, 7.773 real sec
[M::process] read 706990 sequences (100000017 bp) in 2.766 CPU sec, 2.848 real sec...
sorting block 40, #reads = 1069695 mem = 536883624 peak = 905216000
[M::mem_process_seqs] Processed 709306 reads in 171.698 CPU sec, 5.471 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 282045, 26, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 485, 1222)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3256)
[M::mem_pestat] mean and std.dev: (717.95, 676.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4273)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 215, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 642)
[M::mem_pestat] mean and std.dev: (239.28, 117.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 807)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (91, 721, 1106)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3136)
[M::mem_pestat] mean and std.dev: (614.55, 682.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4151)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 404, 1034)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2686)
[M::mem_pestat] mean and std.dev: (658.66, 668.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3512)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706420 sequences (100000194 bp) in 3.345 CPU sec, 4.024 real sec...
sorting block 41, #reads = 1070496 mem = 536878408 peak = 953147392
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 281224, 37, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 281, 739)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1891)
[M::mem_pestat] mean and std.dev: (360.13, 367.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2467)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 217, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 643)
[M::mem_pestat] mean and std.dev: (240.20, 117.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 808)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (532, 1006, 1661)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3919)
[M::mem_pestat] mean and std.dev: (973.56, 600.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5048)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 311, 1007)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2651)
[M::mem_pestat] mean and std.dev: (503.20, 477.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3473)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707894 reads in 232.567 CPU sec, 7.527 real sec
[M::mem_process_seqs] Processed 706990 reads in 169.013 CPU sec, 5.417 real sec
[M::process] read 706068 sequences (100000160 bp) in 2.954 CPU sec, 3.077 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (89, 281151, 45, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 298, 758)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1890)
[M::mem_pestat] mean and std.dev: (482.93, 420.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2456)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 217, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 641)
[M::mem_pestat] mean and std.dev: (240.75, 117.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 805)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (351, 698, 2009)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5325)
[M::mem_pestat] mean and std.dev: (1212.00, 1189.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6983)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 397, 670)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1574)
[M::mem_pestat] mean and std.dev: (403.81, 270.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2026)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 42, #reads = 1070168 mem = 536880127 peak = 953147392
[M::process] read 705698 sequences (100000056 bp) in 3.848 CPU sec, 4.612 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 280993, 41, 96)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 706, 1182)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3018)
[M::mem_pestat] mean and std.dev: (732.27, 613.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3936)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 218, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 639)
[M::mem_pestat] mean and std.dev: (240.31, 116.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 802)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (386, 871, 1747)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4469)
[M::mem_pestat] mean and std.dev: (1036.77, 863.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5830)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 489, 1001)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2545)
[M::mem_pestat] mean and std.dev: (674.61, 653.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3317)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706420 reads in 233.663 CPU sec, 7.606 real sec
[M::mem_process_seqs] Processed 706068 reads in 170.765 CPU sec, 5.483 real sec
[M::process] read 706206 sequences (100000137 bp) in 3.639 CPU sec, 3.884 real sec...
sorting block 43, #reads = 1069148 mem = 536882223 peak = 953147392
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (79, 280734, 48, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 386, 1228)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3314)
[M::mem_pestat] mean and std.dev: (652.78, 678.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4357)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 218, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 645)
[M::mem_pestat] mean and std.dev: (241.43, 117.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 810)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 798, 1793)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4923)
[M::mem_pestat] mean and std.dev: (896.05, 918.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6488)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 303, 865)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2205)
[M::mem_pestat] mean and std.dev: (534.72, 513.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2875)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705890 sequences (100000131 bp) in 3.288 CPU sec, 3.874 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 280952, 34, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 524, 1304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3370)
[M::mem_pestat] mean and std.dev: (865.66, 780.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4403)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 219, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 654)
[M::mem_pestat] mean and std.dev: (243.29, 120.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 822)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (321, 1337, 2637)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7269)
[M::mem_pestat] mean and std.dev: (1426.12, 1218.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9585)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (390, 696, 1587)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3981)
[M::mem_pestat] mean and std.dev: (951.20, 913.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5178)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705698 reads in 234.858 CPU sec, 7.640 real sec
[M::mem_process_seqs] Processed 706206 reads in 171.521 CPU sec, 5.577 real sec
sorting block 44, #reads = 1068369 mem = 536879385 peak = 953147392
[M::process] read 707226 sequences (100000052 bp) in 3.288 CPU sec, 3.591 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 281409, 45, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 518, 1510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4088)
[M::mem_pestat] mean and std.dev: (861.91, 923.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5377)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 220, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 651)
[M::mem_pestat] mean and std.dev: (243.20, 119.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 818)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (369, 999, 2086)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5520)
[M::mem_pestat] mean and std.dev: (1214.25, 982.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7237)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 276, 830)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2134)
[M::mem_pestat] mean and std.dev: (424.73, 458.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2786)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 45, #reads = 1068302 mem = 536884133 peak = 969494528
[M::process] read 716956 sequences (100000089 bp) in 3.501 CPU sec, 4.007 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (89, 281013, 51, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 232, 384)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 844)
[M::mem_pestat] mean and std.dev: (255.25, 166.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1074)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 217, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 649)
[M::mem_pestat] mean and std.dev: (241.75, 120.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 816)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 504, 1355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3707)
[M::mem_pestat] mean and std.dev: (751.02, 721.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4883)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 341, 654)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1466)
[M::mem_pestat] mean and std.dev: (405.31, 271.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1872)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705890 reads in 237.867 CPU sec, 7.713 real sec
[M::mem_process_seqs] Processed 707226 reads in 174.464 CPU sec, 5.609 real sec
[M::process] read 713598 sequences (100000255 bp) in 3.260 CPU sec, 3.545 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 285424, 46, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 405, 1031)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2675)
[M::mem_pestat] mean and std.dev: (613.26, 531.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3497)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 197, 283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 573)
[M::mem_pestat] mean and std.dev: (219.30, 106.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 718)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (106, 563, 1053)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2947)
[M::mem_pestat] mean and std.dev: (665.54, 568.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3894)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 436, 1038)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2680)
[M::mem_pestat] mean and std.dev: (565.93, 494.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3501)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 46, #reads = 1069347 mem = 536877883 peak = 969494528
[M::process] read 711412 sequences (100000297 bp) in 3.815 CPU sec, 4.484 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 284211, 33, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 452, 916)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2310)
[M::mem_pestat] mean and std.dev: (560.56, 460.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3007)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (141, 204, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 603)
[M::mem_pestat] mean and std.dev: (227.71, 112.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 757)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 610, 819)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2153)
[M::mem_pestat] mean and std.dev: (590.84, 531.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2820)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 339, 769)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1853)
[M::mem_pestat] mean and std.dev: (432.81, 399.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2395)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 716956 reads in 246.317 CPU sec, 7.990 real sec
[M::mem_process_seqs] Processed 713598 reads in 173.544 CPU sec, 5.555 real sec
[M::process] read 709984 sequences (100000098 bp) in 3.211 CPU sec, 3.397 real sec...
sorting block 47, #reads = 1069677 mem = 536879810 peak = 969494528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 283245, 40, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 307, 923)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2419)
[M::mem_pestat] mean and std.dev: (494.97, 416.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3167)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 208, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 620)
[M::mem_pestat] mean and std.dev: (232.45, 115.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 779)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (526, 782, 1477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3379)
[M::mem_pestat] mean and std.dev: (931.41, 758.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4330)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 352, 865)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2115)
[M::mem_pestat] mean and std.dev: (423.89, 321.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2740)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 709168 sequences (100000166 bp) in 3.667 CPU sec, 4.229 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 282918, 51, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 295, 741)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1829)
[M::mem_pestat] mean and std.dev: (401.03, 350.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2373)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 211, 308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 634)
[M::mem_pestat] mean and std.dev: (236.24, 118.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 797)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (422, 962, 2720)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7316)
[M::mem_pestat] mean and std.dev: (1590.84, 1707.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9614)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (283, 802, 1467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3835)
[M::mem_pestat] mean and std.dev: (763.31, 659.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5019)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 711412 reads in 235.440 CPU sec, 7.610 real sec
[M::mem_process_seqs] Processed 709984 reads in 170.257 CPU sec, 5.440 real sec
[M::process] read 708662 sequences (100000141 bp) in 3.285 CPU sec, 3.453 real sec...
sorting block 48, #reads = 1073021 mem = 536880078 peak = 969494528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 282379, 42, 85)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 290, 544)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1338)
[M::mem_pestat] mean and std.dev: (337.00, 247.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1735)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 212, 310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 638)
[M::mem_pestat] mean and std.dev: (237.82, 118.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 802)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (339, 744, 1531)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3915)
[M::mem_pestat] mean and std.dev: (862.28, 676.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5107)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 366, 858)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2192)
[M::mem_pestat] mean and std.dev: (401.79, 285.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2859)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707750 sequences (100000086 bp) in 3.650 CPU sec, 4.250 real sec...
sorting block 49, #reads = 1072916 mem = 536879817 peak = 1018593280
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 282013, 37, 93)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 343, 1847)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5069)
[M::mem_pestat] mean and std.dev: (983.50, 1172.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6680)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 214, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 647)
[M::mem_pestat] mean and std.dev: (239.35, 119.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 814)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (286, 626, 2232)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6124)
[M::mem_pestat] mean and std.dev: (1056.91, 1223.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8070)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (286, 412, 1500)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3928)
[M::mem_pestat] mean and std.dev: (873.88, 1021.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5142)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 709168 reads in 239.155 CPU sec, 7.824 real sec
[M::mem_process_seqs] Processed 708662 reads in 173.901 CPU sec, 5.678 real sec
[M::process] read 707272 sequences (100000218 bp) in 2.966 CPU sec, 3.164 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 282125, 42, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 375, 1272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3328)
[M::mem_pestat] mean and std.dev: (746.76, 791.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4356)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 216, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 651)
[M::mem_pestat] mean and std.dev: (241.00, 120.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 819)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 469, 1029)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2713)
[M::mem_pestat] mean and std.dev: (598.24, 605.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3555)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 361, 696)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1686)
[M::mem_pestat] mean and std.dev: (429.12, 338.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2181)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 50, #reads = 1071746 mem = 536879193 peak = 1018593280
[M::process] read 706948 sequences (100000154 bp) in 3.778 CPU sec, 4.298 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 281267, 50, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 418, 1115)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2865)
[M::mem_pestat] mean and std.dev: (675.26, 612.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3740)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 217, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 652)
[M::mem_pestat] mean and std.dev: (241.89, 120.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 820)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (300, 1053, 1998)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5394)
[M::mem_pestat] mean and std.dev: (1335.61, 1234.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7092)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 390, 1234)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3270)
[M::mem_pestat] mean and std.dev: (600.02, 564.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4288)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707750 reads in 244.205 CPU sec, 7.909 real sec
[M::mem_process_seqs] Processed 707272 reads in 178.991 CPU sec, 5.733 real sec
[M::process] read 706720 sequences (100000086 bp) in 2.960 CPU sec, 3.283 real sec...
sorting block 51, #reads = 1069194 mem = 536878366 peak = 1018593280
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (83, 280790, 38, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 272, 744)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1892)
[M::mem_pestat] mean and std.dev: (354.17, 343.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2466)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 217, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 652)
[M::mem_pestat] mean and std.dev: (242.29, 120.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 820)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 1398, 1912)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5438)
[M::mem_pestat] mean and std.dev: (1232.28, 1117.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7201)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 411, 886)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2228)
[M::mem_pestat] mean and std.dev: (575.54, 508.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2899)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706166 sequences (100000157 bp) in 3.957 CPU sec, 4.395 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 280681, 60, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 366, 1320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3538)
[M::mem_pestat] mean and std.dev: (762.05, 790.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4647)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 217, 314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 644)
[M::mem_pestat] mean and std.dev: (241.46, 119.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 809)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 597, 1382)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3804)
[M::mem_pestat] mean and std.dev: (867.23, 906.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5015)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 306, 826)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2102)
[M::mem_pestat] mean and std.dev: (434.50, 402.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2740)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706948 reads in 252.823 CPU sec, 8.138 real sec
[M::process] read 706614 sequences (100000267 bp) in 2.515 CPU sec, 2.559 real sec...
sorting block 52, #reads = 1065466 mem = 536882827 peak = 1018593280
[M::mem_process_seqs] Processed 706720 reads in 183.343 CPU sec, 5.899 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 281095, 32, 87)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 288, 682)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1688)
[M::mem_pestat] mean and std.dev: (447.35, 377.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2191)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 219, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 654)
[M::mem_pestat] mean and std.dev: (243.65, 121.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 822)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (345, 805, 1620)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4170)
[M::mem_pestat] mean and std.dev: (1034.88, 982.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5445)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 469, 1287)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3359)
[M::mem_pestat] mean and std.dev: (793.45, 756.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4395)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 53, #reads = 1065394 mem = 536888265 peak = 1018593280
[M::process] read 706240 sequences (100000152 bp) in 4.220 CPU sec, 4.724 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (79, 281459, 42, 88)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 298, 521)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1165)
[M::mem_pestat] mean and std.dev: (336.76, 217.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1487)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 217, 314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 644)
[M::mem_pestat] mean and std.dev: (240.85, 118.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 809)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (302, 484, 1121)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2759)
[M::mem_pestat] mean and std.dev: (635.34, 493.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3578)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (266, 590, 1456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3836)
[M::mem_pestat] mean and std.dev: (970.29, 914.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5026)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706166 reads in 249.816 CPU sec, 8.093 real sec
[M::process] read 705974 sequences (100000284 bp) in 3.049 CPU sec, 3.171 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (90, 280645, 54, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 480, 1048)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2696)
[M::mem_pestat] mean and std.dev: (634.67, 545.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3520)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 218, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 647)
[M::mem_pestat] mean and std.dev: (242.12, 119.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 813)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 515, 1315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3643)
[M::mem_pestat] mean and std.dev: (752.94, 688.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4807)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 398, 1649)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4445)
[M::mem_pestat] mean and std.dev: (1076.67, 1143.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5843)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706376 sequences (100000177 bp) in 2.797 CPU sec, 2.995 real sec...
[M::mem_process_seqs] Processed 706240 reads in 142.896 CPU sec, 4.562 real sec
sorting block 54, #reads = 1066750 mem = 536877154 peak = 1018593280
[M::mem_process_seqs] Processed 706614 reads in 381.250 CPU sec, 12.281 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 281064, 42, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 344, 849)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2135)
[M::mem_pestat] mean and std.dev: (528.32, 490.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2778)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 219, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 651)
[M::mem_pestat] mean and std.dev: (242.78, 119.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 818)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (362, 800, 1684)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4328)
[M::mem_pestat] mean and std.dev: (1023.74, 925.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5650)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 423, 847)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2067)
[M::mem_pestat] mean and std.dev: (473.63, 310.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2677)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 55, #reads = 1066288 mem = 536887380 peak = 1018593280
[M::process] read 705960 sequences (100000263 bp) in 3.441 CPU sec, 4.211 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (99, 280758, 49, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 415, 1697)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4671)
[M::mem_pestat] mean and std.dev: (823.61, 895.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6158)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 218, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653)
[M::mem_pestat] mean and std.dev: (242.88, 120.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 821)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (381, 808, 1416)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3486)
[M::mem_pestat] mean and std.dev: (809.63, 610.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4521)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 333, 767)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1859)
[M::mem_pestat] mean and std.dev: (465.33, 401.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2405)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705974 reads in 279.853 CPU sec, 9.014 real sec
[M::mem_process_seqs] Processed 706376 reads in 178.851 CPU sec, 5.787 real sec
[M::process] read 719168 sequences (100000084 bp) in 3.172 CPU sec, 3.427 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 281694, 34, 97)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 558, 729)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1743)
[M::mem_pestat] mean and std.dev: (538.06, 396.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2250)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 219, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 657)
[M::mem_pestat] mean and std.dev: (243.92, 121.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 826)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 863, 2397)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6721)
[M::mem_pestat] mean and std.dev: (1126.52, 1429.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8883)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 366, 926)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2270)
[M::mem_pestat] mean and std.dev: (606.60, 541.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2942)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 56, #reads = 1065230 mem = 536878475 peak = 1018593280
[M::process] read 718452 sequences (100000116 bp) in 3.832 CPU sec, 4.362 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 286138, 26, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 247, 404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 874)
[M::mem_pestat] mean and std.dev: (272.15, 160.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1109)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 194, 276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 556)
[M::mem_pestat] mean and std.dev: (214.33, 102.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 696)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (461, 919, 1672)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4094)
[M::mem_pestat] mean and std.dev: (989.80, 789.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5305)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 357, 720)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1662)
[M::mem_pestat] mean and std.dev: (408.94, 284.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2133)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705960 reads in 258.602 CPU sec, 8.367 real sec
[M::process] read 714756 sequences (100000247 bp) in 3.054 CPU sec, 3.241 real sec...
[M::mem_process_seqs] Processed 719168 reads in 189.524 CPU sec, 6.074 real sec
sorting block 57, #reads = 1064884 mem = 536886135 peak = 1018593280
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 285392, 33, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 277, 755)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1915)
[M::mem_pestat] mean and std.dev: (441.36, 420.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2495)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 195, 280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 566)
[M::mem_pestat] mean and std.dev: (217.10, 105.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 709)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 721, 1041)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2691)
[M::mem_pestat] mean and std.dev: (586.07, 506.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3516)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 406, 903)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2215)
[M::mem_pestat] mean and std.dev: (552.12, 486.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2871)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 713424 sequences (100000273 bp) in 3.732 CPU sec, 4.213 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 284876, 42, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (260, 664, 1085)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2735)
[M::mem_pestat] mean and std.dev: (714.18, 632.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3560)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (140, 201, 291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 593)
[M::mem_pestat] mean and std.dev: (224.86, 110.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 744)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (348, 886, 1757)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4575)
[M::mem_pestat] mean and std.dev: (1215.78, 1186.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5984)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 287, 818)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2096)
[M::mem_pestat] mean and std.dev: (503.86, 524.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2735)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 718452 reads in 268.199 CPU sec, 8.696 real sec
[M::process] read 711736 sequences (100000137 bp) in 2.846 CPU sec, 3.137 real sec...
sorting block 58, #reads = 1070196 mem = 536882809 peak = 1018593280
[M::mem_process_seqs] Processed 714756 reads in 187.979 CPU sec, 6.045 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 283941, 60, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 366, 1627)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4589)
[M::mem_pestat] mean and std.dev: (822.04, 941.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6070)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (141, 203, 294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 600)
[M::mem_pestat] mean and std.dev: (226.79, 111.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 753)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (72, 411, 1353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3915)
[M::mem_pestat] mean and std.dev: (777.24, 909.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5196)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 247, 704)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1740)
[M::mem_pestat] mean and std.dev: (393.84, 396.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2258)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 59, #reads = 1066946 mem = 536887097 peak = 1018593280
[M::process] read 711960 sequences (100000018 bp) in 3.932 CPU sec, 4.474 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 284179, 39, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 397, 996)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2594)
[M::mem_pestat] mean and std.dev: (424.45, 333.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3393)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 207, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 617)
[M::mem_pestat] mean and std.dev: (231.46, 114.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 775)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 527, 1717)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4815)
[M::mem_pestat] mean and std.dev: (754.61, 787.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6364)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 309, 634)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1520)
[M::mem_pestat] mean and std.dev: (326.44, 190.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1963)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 713424 reads in 255.629 CPU sec, 8.227 real sec
[M::process] read 710854 sequences (100000166 bp) in 2.913 CPU sec, 3.151 real sec...
[M::mem_process_seqs] Processed 711736 reads in 186.817 CPU sec, 5.973 real sec
sorting block 60, #reads = 1068133 mem = 536880469 peak = 1018593280
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 284004, 35, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 571, 1149)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2951)
[M::mem_pestat] mean and std.dev: (674.39, 513.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3852)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 207, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 617)
[M::mem_pestat] mean and std.dev: (231.66, 114.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 775)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (567, 849, 1406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3084)
[M::mem_pestat] mean and std.dev: (891.72, 595.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3923)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 426, 2200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6110)
[M::mem_pestat] mean and std.dev: (988.19, 1202.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8065)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 710222 sequences (100000255 bp) in 3.593 CPU sec, 3.911 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (79, 283587, 41, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 415, 1016)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2648)
[M::mem_pestat] mean and std.dev: (627.10, 581.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3464)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 209, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 627)
[M::mem_pestat] mean and std.dev: (234.06, 116.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 788)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (353, 473, 1901)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4997)
[M::mem_pestat] mean and std.dev: (990.29, 870.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6545)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 295, 1000)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2582)
[M::mem_pestat] mean and std.dev: (554.60, 535.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3373)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 709366 sequences (100000018 bp) in 2.490 CPU sec, 2.595 real sec...
[M::mem_process_seqs] Processed 711960 reads in 251.179 CPU sec, 8.100 real sec
[M::mem_process_seqs] Processed 710854 reads in 181.443 CPU sec, 5.830 real sec
sorting block 61, #reads = 1069749 mem = 536879615 peak = 1018593280
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 282746, 36, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 369, 1373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3697)
[M::mem_pestat] mean and std.dev: (660.24, 738.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4859)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 211, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 631)
[M::mem_pestat] mean and std.dev: (235.68, 117.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 793)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 455, 2589)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7375)
[M::mem_pestat] mean and std.dev: (1178.44, 1251.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9768)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 369, 732)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1710)
[M::mem_pestat] mean and std.dev: (415.74, 287.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2199)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707892 sequences (100000269 bp) in 3.452 CPU sec, 4.076 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 282050, 42, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 536, 1363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3659)
[M::mem_pestat] mean and std.dev: (826.92, 800.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4807)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 212, 309)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 637)
[M::mem_pestat] mean and std.dev: (237.03, 118.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 801)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 402, 1314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3602)
[M::mem_pestat] mean and std.dev: (565.94, 694.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4746)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 552, 932)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2318)
[M::mem_pestat] mean and std.dev: (582.40, 425.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3011)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 710222 reads in 252.788 CPU sec, 8.142 real sec
[M::process] read 707772 sequences (100000022 bp) in 2.757 CPU sec, 2.970 real sec...
sorting block 62, #reads = 1067764 mem = 536879451 peak = 1018593280
[M::mem_process_seqs] Processed 709366 reads in 183.300 CPU sec, 5.898 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 281617, 50, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 485, 1352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3602)
[M::mem_pestat] mean and std.dev: (820.47, 867.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4727)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 215, 311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 639)
[M::mem_pestat] mean and std.dev: (239.00, 118.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 803)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (359, 614, 1097)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2573)
[M::mem_pestat] mean and std.dev: (716.68, 588.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3311)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 421, 924)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2326)
[M::mem_pestat] mean and std.dev: (577.70, 480.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3027)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 63, #reads = 1067042 mem = 536881097 peak = 1018593280
[M::process] read 707320 sequences (100000049 bp) in 3.607 CPU sec, 4.317 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 280979, 47, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 290, 1403)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3819)
[M::mem_pestat] mean and std.dev: (701.11, 689.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5027)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 215, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 642)
[M::mem_pestat] mean and std.dev: (239.52, 118.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 807)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (389, 731, 1643)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4151)
[M::mem_pestat] mean and std.dev: (945.48, 799.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5405)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 319, 894)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2298)
[M::mem_pestat] mean and std.dev: (480.66, 449.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3000)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707892 reads in 250.825 CPU sec, 8.142 real sec
[M::process] read 707198 sequences (100000076 bp) in 2.770 CPU sec, 2.811 real sec...
[M::mem_process_seqs] Processed 707772 reads in 182.817 CPU sec, 6.188 real sec
sorting block 64, #reads = 1065876 mem = 536879055 peak = 1018593280
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 281276, 51, 91)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 305, 610)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1494)
[M::mem_pestat] mean and std.dev: (310.14, 203.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1936)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 216, 314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 646)
[M::mem_pestat] mean and std.dev: (240.81, 119.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 812)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 747, 1525)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4269)
[M::mem_pestat] mean and std.dev: (983.18, 926.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5641)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 404, 1025)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2665)
[M::mem_pestat] mean and std.dev: (573.63, 501.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3485)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705842 sequences (100000140 bp) in 3.426 CPU sec, 3.987 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (87, 281481, 35, 81)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 380, 1079)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2887)
[M::mem_pestat] mean and std.dev: (559.30, 582.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3791)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 216, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 643)
[M::mem_pestat] mean and std.dev: (240.53, 119.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 808)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (472, 811, 1497)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3547)
[M::mem_pestat] mean and std.dev: (945.72, 721.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4572)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 357, 643)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1515)
[M::mem_pestat] mean and std.dev: (461.28, 369.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1951)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707320 reads in 250.617 CPU sec, 8.398 real sec
[M::process] read 706310 sequences (100000162 bp) in 3.006 CPU sec, 3.146 real sec...
[M::mem_process_seqs] Processed 707198 reads in 181.593 CPU sec, 5.851 real sec
sorting block 65, #reads = 1065039 mem = 536880173 peak = 1018593280
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (100, 280656, 58, 92)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 401, 1107)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2897)
[M::mem_pestat] mean and std.dev: (597.31, 596.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3792)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 219, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 654)
[M::mem_pestat] mean and std.dev: (243.46, 120.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 822)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (307, 769, 1615)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4231)
[M::mem_pestat] mean and std.dev: (953.04, 936.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5539)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 442, 1119)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2899)
[M::mem_pestat] mean and std.dev: (679.23, 649.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3789)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 710662 sequences (100000245 bp) in 3.819 CPU sec, 4.434 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 280779, 39, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 287, 748)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1908)
[M::mem_pestat] mean and std.dev: (385.78, 366.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2488)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 218, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 650)
[M::mem_pestat] mean and std.dev: (242.66, 120.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 817)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (439, 597, 1318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3076)
[M::mem_pestat] mean and std.dev: (767.94, 593.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3955)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (269, 663, 1507)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3983)
[M::mem_pestat] mean and std.dev: (747.31, 731.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5221)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705842 reads in 243.020 CPU sec, 7.883 real sec
[M::process] read 716780 sequences (100000090 bp) in 2.731 CPU sec, 2.847 real sec...
sorting block 66, #reads = 1066088 mem = 536877060 peak = 1018593280
[M::mem_process_seqs] Processed 706310 reads in 179.251 CPU sec, 5.731 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 282581, 59, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 394, 1056)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2666)
[M::mem_pestat] mean and std.dev: (569.50, 540.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3471)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 208, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 618)
[M::mem_pestat] mean and std.dev: (232.29, 114.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 776)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (289, 627, 1414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3664)
[M::mem_pestat] mean and std.dev: (857.84, 832.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4789)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (275, 566, 1245)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3185)
[M::mem_pestat] mean and std.dev: (773.56, 777.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4155)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 67, #reads = 1067465 mem = 536884892 peak = 1058725888
[M::process] read 714864 sequences (100000013 bp) in 3.584 CPU sec, 4.203 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 285670, 28, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 236, 598)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1456)
[M::mem_pestat] mean and std.dev: (315.32, 249.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1885)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 198, 286)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 582)
[M::mem_pestat] mean and std.dev: (221.16, 108.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 730)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (409, 738, 1330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3172)
[M::mem_pestat] mean and std.dev: (801.77, 641.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4093)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 328, 1018)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2664)
[M::mem_pestat] mean and std.dev: (575.98, 569.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3487)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 712116 sequences (100000053 bp) in 2.781 CPU sec, 2.815 real sec...
[M::mem_process_seqs] Processed 710662 reads in 259.848 CPU sec, 8.400 real sec
[M::mem_process_seqs] Processed 716780 reads in 177.831 CPU sec, 5.747 real sec
sorting block 68, #reads = 1064630 mem = 536876350 peak = 1058725888
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 284679, 32, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 367, 1063)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2825)
[M::mem_pestat] mean and std.dev: (653.16, 725.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3706)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (140, 202, 293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 599)
[M::mem_pestat] mean and std.dev: (225.86, 111.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 752)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 399, 1307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3617)
[M::mem_pestat] mean and std.dev: (565.57, 559.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4772)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 306, 980)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2624)
[M::mem_pestat] mean and std.dev: (559.57, 587.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3446)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 710978 sequences (100000242 bp) in 3.760 CPU sec, 4.222 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 283669, 48, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (269, 643, 1678)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4496)
[M::mem_pestat] mean and std.dev: (1084.98, 1107.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5905)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 206, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 611)
[M::mem_pestat] mean and std.dev: (229.97, 112.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 767)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (275, 542, 725)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1625)
[M::mem_pestat] mean and std.dev: (538.56, 384.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2075)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 353, 1997)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5521)
[M::mem_pestat] mean and std.dev: (1130.19, 1452.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7283)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 714864 reads in 232.889 CPU sec, 7.747 real sec
[M::mem_process_seqs] Processed 712116 reads in 166.422 CPU sec, 5.458 real sec
[M::process] read 710104 sequences (100000031 bp) in 2.732 CPU sec, 2.981 real sec...
sorting block 69, #reads = 1075828 mem = 536882041 peak = 1058725888
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (79, 283408, 38, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 330, 1072)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2806)
[M::mem_pestat] mean and std.dev: (659.99, 605.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3673)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 210, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 624)
[M::mem_pestat] mean and std.dev: (233.70, 115.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 784)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (462, 977, 1338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3090)
[M::mem_pestat] mean and std.dev: (998.22, 667.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3966)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 433, 872)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2160)
[M::mem_pestat] mean and std.dev: (501.04, 395.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2804)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 710384 sequences (100000225 bp) in 3.935 CPU sec, 4.380 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 283410, 33, 81)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 322, 687)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1699)
[M::mem_pestat] mean and std.dev: (371.57, 293.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2205)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 211, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 631)
[M::mem_pestat] mean and std.dev: (235.60, 116.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 793)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (401, 595, 1548)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3842)
[M::mem_pestat] mean and std.dev: (839.23, 722.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4989)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (262, 425, 1390)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3646)
[M::mem_pestat] mean and std.dev: (663.51, 621.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4774)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 710978 reads in 236.936 CPU sec, 7.638 real sec
sorting block 70, #reads = 1074380 mem = 536888651 peak = 1058725888
[M::mem_process_seqs] Processed 710104 reads in 172.145 CPU sec, 5.495 real sec
[M::process] read 710820 sequences (100000167 bp) in 3.103 CPU sec, 3.301 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 283562, 41, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 357, 621)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1501)
[M::mem_pestat] mean and std.dev: (383.56, 277.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1941)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 211, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 631)
[M::mem_pestat] mean and std.dev: (235.33, 116.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 793)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 832, 2427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6859)
[M::mem_pestat] mean and std.dev: (1369.10, 1474.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9075)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 353, 752)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1768)
[M::mem_pestat] mean and std.dev: (456.91, 361.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2276)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 71, #reads = 1074245 mem = 536878217 peak = 1058725888
[M::process] read 709448 sequences (100000120 bp) in 3.896 CPU sec, 4.710 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 283138, 49, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 339, 556)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1302)
[M::mem_pestat] mean and std.dev: (355.98, 250.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1675)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 210, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 630)
[M::mem_pestat] mean and std.dev: (234.78, 116.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 792)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 400, 1083)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2977)
[M::mem_pestat] mean and std.dev: (570.83, 501.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3924)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 419, 771)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1845)
[M::mem_pestat] mean and std.dev: (369.28, 191.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2382)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 710384 reads in 238.608 CPU sec, 7.841 real sec
[M::mem_process_seqs] Processed 710820 reads in 170.241 CPU sec, 5.509 real sec
[M::process] read 710206 sequences (100000126 bp) in 3.740 CPU sec, 4.055 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 282187, 40, 88)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 340, 815)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1993)
[M::mem_pestat] mean and std.dev: (469.48, 440.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2582)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 213, 310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 638)
[M::mem_pestat] mean and std.dev: (237.56, 117.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 802)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (100, 654, 1719)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4957)
[M::mem_pestat] mean and std.dev: (822.00, 884.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6576)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (291, 677, 1209)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3045)
[M::mem_pestat] mean and std.dev: (636.32, 488.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3963)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 72, #reads = 1071119 mem = 536883427 peak = 1058725888
[M::process] read 709338 sequences (100000191 bp) in 3.584 CPU sec, 4.235 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 282714, 53, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 511, 3481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9941)
[M::mem_pestat] mean and std.dev: (1977.10, 2619.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13171)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 210, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 625)
[M::mem_pestat] mean and std.dev: (234.41, 115.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 785)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (366, 763, 1963)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5157)
[M::mem_pestat] mean and std.dev: (1066.04, 1055.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6754)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 343, 657)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1621)
[M::mem_pestat] mean and std.dev: (366.14, 260.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2103)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 709448 reads in 236.104 CPU sec, 7.684 real sec
[M::mem_process_seqs] Processed 710206 reads in 172.149 CPU sec, 5.564 real sec
[M::process] read 708756 sequences (100000069 bp) in 3.454 CPU sec, 3.763 real sec...
sorting block 73, #reads = 1071288 mem = 536882731 peak = 1058725888
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (84, 282322, 40, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 395, 1005)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2613)
[M::mem_pestat] mean and std.dev: (607.06, 617.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3417)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 213, 310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 638)
[M::mem_pestat] mean and std.dev: (237.62, 118.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 802)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 436, 837)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2055)
[M::mem_pestat] mean and std.dev: (464.89, 362.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2664)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 557, 1095)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2807)
[M::mem_pestat] mean and std.dev: (705.43, 626.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3663)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707952 sequences (100000294 bp) in 3.779 CPU sec, 4.438 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 281410, 47, 93)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 381, 754)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1870)
[M::mem_pestat] mean and std.dev: (464.78, 394.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2428)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 214, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 644)
[M::mem_pestat] mean and std.dev: (239.04, 118.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 810)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (130, 440, 756)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2008)
[M::mem_pestat] mean and std.dev: (473.07, 414.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2634)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 306, 1559)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4257)
[M::mem_pestat] mean and std.dev: (863.19, 1040.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5606)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 709338 reads in 249.347 CPU sec, 8.088 real sec
sorting block 74, #reads = 1071554 mem = 536891037 peak = 1058725888
[M::mem_process_seqs] Processed 708756 reads in 182.560 CPU sec, 5.858 real sec
[M::process] read 707866 sequences (100000191 bp) in 3.360 CPU sec, 3.661 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 281720, 45, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 547, 816)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2048)
[M::mem_pestat] mean and std.dev: (567.66, 455.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2664)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 215, 311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 639)
[M::mem_pestat] mean and std.dev: (238.93, 118.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 803)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (249, 854, 2262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6288)
[M::mem_pestat] mean and std.dev: (1190.21, 1104.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8301)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 335, 784)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1950)
[M::mem_pestat] mean and std.dev: (496.04, 393.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2533)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 75, #reads = 1067895 mem = 536883408 peak = 1058725888
[M::process] read 707466 sequences (100000211 bp) in 3.747 CPU sec, 4.152 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (83, 281674, 50, 90)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 348, 891)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2313)
[M::mem_pestat] mean and std.dev: (555.76, 503.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3024)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 214, 310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 636)
[M::mem_pestat] mean and std.dev: (238.21, 117.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 799)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (252, 697, 1126)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2874)
[M::mem_pestat] mean and std.dev: (779.07, 651.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3748)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 280, 807)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2011)
[M::mem_pestat] mean and std.dev: (416.95, 423.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2613)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707952 reads in 251.629 CPU sec, 8.161 real sec
[M::mem_process_seqs] Processed 707866 reads in 181.558 CPU sec, 5.847 real sec
[M::process] read 707230 sequences (100000248 bp) in 3.224 CPU sec, 3.577 real sec...
sorting block 76, #reads = 1067379 mem = 536879289 peak = 1058725888
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 281194, 44, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 485, 1153)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3089)
[M::mem_pestat] mean and std.dev: (653.26, 617.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4057)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 216, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 643)
[M::mem_pestat] mean and std.dev: (240.09, 118.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 808)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (424, 698, 1792)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4528)
[M::mem_pestat] mean and std.dev: (944.21, 902.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5896)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 339, 683)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1537)
[M::mem_pestat] mean and std.dev: (436.10, 306.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1964)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707014 sequences (100000062 bp) in 3.690 CPU sec, 4.160 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 281439, 46, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 329, 862)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2288)
[M::mem_pestat] mean and std.dev: (499.03, 455.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3001)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 216, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 643)
[M::mem_pestat] mean and std.dev: (240.45, 119.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 808)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (327, 600, 1298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3240)
[M::mem_pestat] mean and std.dev: (760.15, 728.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4211)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 465, 1323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3553)
[M::mem_pestat] mean and std.dev: (650.53, 559.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4668)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707466 reads in 255.472 CPU sec, 8.286 real sec
[M::process] read 715140 sequences (100000188 bp) in 2.942 CPU sec, 3.187 real sec...
[M::mem_process_seqs] Processed 707230 reads in 188.305 CPU sec, 6.066 real sec
sorting block 77, #reads = 1066127 mem = 536879684 peak = 1058725888
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (81, 281089, 33, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 371, 1357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3619)
[M::mem_pestat] mean and std.dev: (788.81, 858.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4750)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 216, 314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 646)
[M::mem_pestat] mean and std.dev: (241.02, 119.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 812)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (575, 830, 1986)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4808)
[M::mem_pestat] mean and std.dev: (1050.93, 774.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6219)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (260, 430, 866)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2078)
[M::mem_pestat] mean and std.dev: (588.23, 407.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2684)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720966 sequences (100000250 bp) in 2.861 CPU sec, 3.026 real sec...
[M::process] read 717632 sequences (100000083 bp) in 2.200 CPU sec, 2.194 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 283388, 43, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 448, 940)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2456)
[M::mem_pestat] mean and std.dev: (600.00, 556.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3214)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (140, 201, 290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 590)
[M::mem_pestat] mean and std.dev: (224.16, 110.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 740)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 779, 1401)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3827)
[M::mem_pestat] mean and std.dev: (823.83, 768.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5040)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (280, 525, 1795)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4825)
[M::mem_pestat] mean and std.dev: (1048.07, 1163.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6340)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707014 reads in 274.856 CPU sec, 8.810 real sec
sorting block 78, #reads = 1064478 mem = 536878689 peak = 1058725888
[M::mem_process_seqs] Processed 715140 reads in 207.294 CPU sec, 6.622 real sec
sorting block 79, #reads = 1055757 mem = 536881682 peak = 1058725888
[M::process] read 716086 sequences (100000251 bp) in 3.516 CPU sec, 3.774 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 286400, 36, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 389, 1413)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3829)
[M::mem_pestat] mean and std.dev: (821.57, 874.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5037)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 191, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 552)
[M::mem_pestat] mean and std.dev: (212.99, 102.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 691)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 817, 1126)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2850)
[M::mem_pestat] mean and std.dev: (781.21, 609.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3712)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 494, 998)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2492)
[M::mem_pestat] mean and std.dev: (568.07, 478.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3239)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 714330 sequences (100000017 bp) in 2.558 CPU sec, 2.600 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 285667, 42, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 366, 672)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1622)
[M::mem_pestat] mean and std.dev: (419.60, 322.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2097)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 197, 284)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 578)
[M::mem_pestat] mean and std.dev: (219.62, 107.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 725)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (327, 776, 2021)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5409)
[M::mem_pestat] mean and std.dev: (1179.32, 1144.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7103)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 463, 1066)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2778)
[M::mem_pestat] mean and std.dev: (566.62, 485.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3634)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 720966 reads in 272.388 CPU sec, 8.722 real sec
[M::mem_process_seqs] Processed 717632 reads in 190.654 CPU sec, 6.138 real sec
sorting block 80, #reads = 1069396 mem = 536879537 peak = 1058725888
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 285182, 35, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 393, 1259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3371)
[M::mem_pestat] mean and std.dev: (699.61, 678.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4427)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 200, 290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 592)
[M::mem_pestat] mean and std.dev: (223.70, 109.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 743)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 559, 1473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4031)
[M::mem_pestat] mean and std.dev: (742.27, 657.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5310)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 424, 1607)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4371)
[M::mem_pestat] mean and std.dev: (801.11, 838.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5753)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 713084 sequences (100000136 bp) in 3.669 CPU sec, 4.129 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 283960, 43, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 429, 1634)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4478)
[M::mem_pestat] mean and std.dev: (859.08, 963.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5900)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (141, 203, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 603)
[M::mem_pestat] mean and std.dev: (227.06, 111.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 757)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (423, 781, 1726)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4332)
[M::mem_pestat] mean and std.dev: (1092.60, 1096.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5635)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 318, 546)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1164)
[M::mem_pestat] mean and std.dev: (306.22, 134.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1473)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 713424 sequences (100000032 bp) in 2.761 CPU sec, 2.810 real sec...
[M::mem_process_seqs] Processed 716086 reads in 270.760 CPU sec, 9.035 real sec
[M::mem_process_seqs] Processed 714330 reads in 187.844 CPU sec, 5.999 real sec
sorting block 81, #reads = 1067966 mem = 536879857 peak = 1058725888
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (91, 284435, 37, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 337, 549)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1241)
[M::mem_pestat] mean and std.dev: (358.58, 220.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1587)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 206, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 613)
[M::mem_pestat] mean and std.dev: (230.41, 114.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 770)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 571, 1353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3667)
[M::mem_pestat] mean and std.dev: (767.97, 713.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4824)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 343, 679)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1649)
[M::mem_pestat] mean and std.dev: (375.92, 310.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2134)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 712292 sequences (100000007 bp) in 3.908 CPU sec, 4.371 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 283576, 32, 99)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 414, 1958)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5534)
[M::mem_pestat] mean and std.dev: (973.48, 1231.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7322)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (141, 205, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 609)
[M::mem_pestat] mean and std.dev: (229.05, 113.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 765)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (310, 615, 1370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3490)
[M::mem_pestat] mean and std.dev: (658.90, 526.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4550)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 443, 1150)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3040)
[M::mem_pestat] mean and std.dev: (486.44, 481.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3985)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 712676 sequences (100000257 bp) in 2.631 CPU sec, 2.636 real sec...
[M::mem_process_seqs] Processed 713084 reads in 251.096 CPU sec, 8.015 real sec
sorting block 82, #reads = 1066981 mem = 536883726 peak = 1058725888
[M::mem_process_seqs] Processed 713424 reads in 176.044 CPU sec, 5.574 real sec
sorting block 83, #reads = 1068447 mem = 536886623 peak = 1058725888
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (79, 283157, 43, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 348, 1346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3636)
[M::mem_pestat] mean and std.dev: (731.97, 862.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4781)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 207, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 620)
[M::mem_pestat] mean and std.dev: (231.76, 115.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 779)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (368, 1342, 2028)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5348)
[M::mem_pestat] mean and std.dev: (1369.35, 1084.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7008)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (289, 520, 1249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3169)
[M::mem_pestat] mean and std.dev: (619.69, 475.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4129)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 710188 sequences (100000294 bp) in 3.501 CPU sec, 3.617 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 283675, 31, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 598, 1322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3464)
[M::mem_pestat] mean and std.dev: (669.23, 604.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4535)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 206, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 607)
[M::mem_pestat] mean and std.dev: (228.96, 112.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 762)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (123, 483, 1213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3393)
[M::mem_pestat] mean and std.dev: (723.16, 701.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4483)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 369, 1385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3687)
[M::mem_pestat] mean and std.dev: (784.43, 860.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4838)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708440 sequences (100000071 bp) in 2.742 CPU sec, 2.751 real sec...
[M::mem_process_seqs] Processed 712292 reads in 234.847 CPU sec, 7.437 real sec
[M::mem_process_seqs] Processed 712676 reads in 183.050 CPU sec, 5.848 real sec
sorting block 84, #reads = 1067781 mem = 536885501 peak = 1058725888
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (93, 282103, 43, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (253, 627, 1162)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2980)
[M::mem_pestat] mean and std.dev: (740.86, 629.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3889)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 211, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 628)
[M::mem_pestat] mean and std.dev: (234.91, 115.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 789)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 811, 1576)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4324)
[M::mem_pestat] mean and std.dev: (1191.27, 1375.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6692)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (268, 455, 1086)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2722)
[M::mem_pestat] mean and std.dev: (665.04, 518.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3540)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707232 sequences (100000089 bp) in 3.542 CPU sec, 3.731 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (89, 281900, 54, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 335, 767)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1897)
[M::mem_pestat] mean and std.dev: (397.13, 333.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2462)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 214, 310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 636)
[M::mem_pestat] mean and std.dev: (238.18, 117.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 799)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 888, 2005)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5697)
[M::mem_pestat] mean and std.dev: (1209.52, 1294.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7543)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 440, 1347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3607)
[M::mem_pestat] mean and std.dev: (805.86, 820.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4737)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707012 sequences (100000247 bp) in 2.364 CPU sec, 2.370 real sec...
[M::mem_process_seqs] Processed 710188 reads in 251.730 CPU sec, 8.032 real sec
sorting block 85, #reads = 1067664 mem = 536878065 peak = 1058725888
[M::mem_process_seqs] Processed 708440 reads in 179.879 CPU sec, 5.726 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 281232, 42, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (262, 631, 1517)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4027)
[M::mem_pestat] mean and std.dev: (827.87, 852.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5282)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 216, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 640)
[M::mem_pestat] mean and std.dev: (239.61, 117.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 804)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (337, 671, 1605)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4141)
[M::mem_pestat] mean and std.dev: (1001.64, 902.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5409)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 297, 635)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1507)
[M::mem_pestat] mean and std.dev: (402.35, 316.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1943)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 86, #reads = 1066642 mem = 536876344 peak = 1058725888
[M::process] read 705832 sequences (100000064 bp) in 3.808 CPU sec, 4.051 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (84, 281390, 43, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 480, 1466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3956)
[M::mem_pestat] mean and std.dev: (806.82, 831.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5201)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 216, 309)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 631)
[M::mem_pestat] mean and std.dev: (237.95, 115.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 792)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (338, 895, 1823)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4793)
[M::mem_pestat] mean and std.dev: (1026.28, 844.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6278)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 378, 1119)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2909)
[M::mem_pestat] mean and std.dev: (785.12, 798.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3980)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707232 reads in 213.135 CPU sec, 7.095 real sec
[M::process] read 705344 sequences (100000111 bp) in 3.058 CPU sec, 3.107 real sec...
[M::mem_process_seqs] Processed 707012 reads in 138.275 CPU sec, 4.355 real sec
sorting block 87, #reads = 1067420 mem = 536883175 peak = 1058725888
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (81, 280270, 37, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 348, 1094)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2896)
[M::mem_pestat] mean and std.dev: (606.50, 665.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3797)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 219, 314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 642)
[M::mem_pestat] mean and std.dev: (241.16, 116.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 806)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (417, 1014, 2565)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6861)
[M::mem_pestat] mean and std.dev: (1020.03, 1176.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9009)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 344, 1115)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2939)
[M::mem_pestat] mean and std.dev: (658.17, 627.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3851)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705262 sequences (100000230 bp) in 3.523 CPU sec, 3.710 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (85, 280395, 32, 86)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 442, 1011)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2623)
[M::mem_pestat] mean and std.dev: (607.67, 488.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3429)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 219, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 648)
[M::mem_pestat] mean and std.dev: (242.60, 118.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 814)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (99, 438, 1399)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3999)
[M::mem_pestat] mean and std.dev: (801.78, 903.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5299)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 428, 940)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2412)
[M::mem_pestat] mean and std.dev: (552.90, 467.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3148)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705832 reads in 194.973 CPU sec, 6.229 real sec
[M::process] read 623620 sequences (88276723 bp) in 2.587 CPU sec, 2.629 real sec...
[M::mem_process_seqs] Processed 705344 reads in 145.927 CPU sec, 4.597 real sec
sorting block 88, #reads = 1065711 mem = 536886734 peak = 1058725888
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (84, 280564, 33, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 358, 1194)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3166)
[M::mem_pestat] mean and std.dev: (647.35, 701.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4152)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 220, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 657)
[M::mem_pestat] mean and std.dev: (244.37, 120.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 826)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (390, 908, 1325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3195)
[M::mem_pestat] mean and std.dev: (945.97, 695.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4130)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 361, 1040)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2744)
[M::mem_pestat] mean and std.dev: (594.04, 625.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3596)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705262 reads in 123.250 CPU sec, 4.051 real sec
sorting block 89, #reads = 1066847 mem = 536883617 peak = 1101893632
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 247892, 48, 86)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 285, 1112)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3016)
[M::mem_pestat] mean and std.dev: (675.52, 782.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3968)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 218, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 656)
[M::mem_pestat] mean and std.dev: (243.35, 121.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 825)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (347, 885, 1525)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3881)
[M::mem_pestat] mean and std.dev: (793.88, 579.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5059)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 381, 1055)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2727)
[M::mem_pestat] mean and std.dev: (630.85, 569.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3563)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 623620 reads in 148.966 CPU sec, 4.929 real sec
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000c06f2
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: INTEL(R) XEON(R) PLATINUM 8559C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 96333516
overall: 70648369152 mem 20241.662 user 382.657 sys 687.704 real
sorting block 90, #reads = 1005558 mem = 507346208 peak = 1101893632
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1136_3WJ-T1-TDNA-1_A23MHWWLT4_1.L004\tPU:L004\tSM:1136_3WJ-T1-TDNA-1_A23MHWWLT4_1\tLB:1136_3WJ-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1136_3WJ-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1136_3WJ-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 687.756 sec; CPU: 20624.337 sec
uniq header count 1
merging 91 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000c06f2
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: INTEL(R) XEON(R) PLATINUM 8559C
threads: 31 max 192
algo: util-sort
license: sentieon:util=1
output file size: 5718844599
output reads: 97256330
bam_mem_sort: 91 calls 64.582 user 1.858 sys 67.946 real
bam_write: 91 calls 69.156 user 5.297 sys 141.427 real
execute: 1 calls 34.489 user 1.862 sys 733.842 real
merge_files: 1 calls 34.455 user 1.839 sys 45.393 real
parse_chunk: 1456 calls 89.847 user 22.484 sys 138.460 real
read_chunk: 3946 calls 57.455 user 23.836 sys 632.263 real
sort_block: 1 calls 40.128 user 23.100 sys 610.641 real
write_chunk: 2488 calls 33.860 user 1.507 sys 44.084 real
overall: 3424346112 mem 1777.889 user 74.847 sys 733.864 real
ls: cannot access '*.cram': No such file or directory