cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1136_4GR-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 2386.191 CPU sec, 91.002 real sec
[M::process] read 703116 sequences (100000065 bp) in 1.337 CPU sec, 1.339 real sec...
[M::process] read 700240 sequences (100000021 bp) in 1.858 CPU sec, 1.962 real sec...
[M::process] read 699982 sequences (100000014 bp) in 1.588 CPU sec, 1.599 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 285682, 18, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 324, 664)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1598)
[M::mem_pestat] mean and std.dev: (425.98, 297.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2065)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 226, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (253.99, 129.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 877)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (520, 970, 1701)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4063)
[M::mem_pestat] mean and std.dev: (1297.17, 1119.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5774)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 443, 906)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2382)
[M::mem_pestat] mean and std.dev: (515.97, 440.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3120)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698892 sequences (100000102 bp) in 1.569 CPU sec, 1.573 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 284310, 27, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 508, 776)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1912)
[M::mem_pestat] mean and std.dev: (548.53, 435.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2480)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 725)
[M::mem_pestat] mean and std.dev: (263.13, 134.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 914)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (376, 554, 1022)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2314)
[M::mem_pestat] mean and std.dev: (665.92, 472.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2960)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 356, 836)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2048)
[M::mem_pestat] mean and std.dev: (470.81, 355.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2654)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 284494, 31, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 478, 2192)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6170)
[M::mem_pestat] mean and std.dev: (1013.76, 1109.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8159)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 236, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 734)
[M::mem_pestat] mean and std.dev: (264.81, 135.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 926)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 399, 1096)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2900)
[M::mem_pestat] mean and std.dev: (693.47, 646.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3802)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 489, 997)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2501)
[M::mem_pestat] mean and std.dev: (547.69, 422.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3253)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703116 reads in 301.661 CPU sec, 9.756 real sec
[M::mem_process_seqs] Processed 700240 reads in 207.240 CPU sec, 6.721 real sec
[M::mem_process_seqs] Processed 699982 reads in 229.676 CPU sec, 7.446 real sec
sorting block 0, #reads = 1079219 mem = 536880718 peak = 571146240
[M::process] read 698712 sequences (100000018 bp) in 2.396 CPU sec, 2.584 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 284315, 24, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 228, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (252.39, 107.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 855)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 239, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 738)
[M::mem_pestat] mean and std.dev: (267.01, 136.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 931)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 596, 1678)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4606)
[M::mem_pestat] mean and std.dev: (791.41, 833.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6070)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 255, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 945)
[M::mem_pestat] mean and std.dev: (230.93, 78.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1198)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697944 sequences (100000131 bp) in 2.471 CPU sec, 2.759 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 284531, 17, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (328, 502, 797)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1735)
[M::mem_pestat] mean and std.dev: (452.68, 251.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2204)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 241, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (269.44, 137.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 948)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (270, 505, 1528)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4044)
[M::mem_pestat] mean and std.dev: (663.00, 752.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5302)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 536, 1596)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4278)
[M::mem_pestat] mean and std.dev: (861.24, 914.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5619)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698892 reads in 191.555 CPU sec, 6.144 real sec
sorting block 1, #reads = 1078211 mem = 536879650 peak = 753598464
[M::process] read 697234 sequences (100000118 bp) in 1.825 CPU sec, 1.855 real sec...
[M::mem_process_seqs] Processed 698712 reads in 128.757 CPU sec, 4.349 real sec
sorting block 2, #reads = 1076658 mem = 536879979 peak = 853118976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 284016, 22, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 507, 1540)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4168)
[M::mem_pestat] mean and std.dev: (748.17, 707.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5482)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 243, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 752)
[M::mem_pestat] mean and std.dev: (271.01, 138.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (121, 722, 1448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4102)
[M::mem_pestat] mean and std.dev: (735.57, 752.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5429)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 280, 563)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1207)
[M::mem_pestat] mean and std.dev: (372.64, 263.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1529)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697034 sequences (100000123 bp) in 2.402 CPU sec, 2.568 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 284027, 27, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 305, 691)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1703)
[M::mem_pestat] mean and std.dev: (398.72, 279.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2209)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 245, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (274.26, 140.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 963)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (532, 680, 740)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (116, 1156)
[M::mem_pestat] mean and std.dev: (594.75, 107.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1364)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (320, 382, 879)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1997)
[M::mem_pestat] mean and std.dev: (563.83, 428.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2556)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696844 sequences (100000172 bp) in 1.915 CPU sec, 1.925 real sec...
[M::mem_process_seqs] Processed 697944 reads in 193.342 CPU sec, 6.445 real sec
[M::mem_process_seqs] Processed 697234 reads in 123.622 CPU sec, 3.945 real sec
sorting block 3, #reads = 1076574 mem = 536884501 peak = 853118976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 283924, 20, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 447, 1424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3832)
[M::mem_pestat] mean and std.dev: (717.52, 904.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5036)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 245, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (273.46, 139.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 955)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (419, 737, 1143)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2591)
[M::mem_pestat] mean and std.dev: (647.50, 352.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3315)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (288, 491, 2417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6675)
[M::mem_pestat] mean and std.dev: (1077.43, 1142.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8804)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696114 sequences (100000130 bp) in 2.089 CPU sec, 2.229 real sec...
[M::process] read 696024 sequences (100000212 bp) in 1.332 CPU sec, 1.333 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 283344, 21, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (296, 444, 533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1007)
[M::mem_pestat] mean and std.dev: (396.63, 165.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1244)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 247, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 769)
[M::mem_pestat] mean and std.dev: (275.92, 141.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 971)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (310, 840, 2293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6259)
[M::mem_pestat] mean and std.dev: (1134.38, 946.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8242)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 441, 885)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2227)
[M::mem_pestat] mean and std.dev: (569.68, 451.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2898)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697034 reads in 182.559 CPU sec, 5.851 real sec
[M::mem_process_seqs] Processed 696844 reads in 123.279 CPU sec, 4.313 real sec
sorting block 4, #reads = 1075530 mem = 536882067 peak = 853118976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283524, 24, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 402, 1358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3792)
[M::mem_pestat] mean and std.dev: (746.91, 873.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5009)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 248, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (276.82, 141.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 976)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (446, 1039, 1706)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4226)
[M::mem_pestat] mean and std.dev: (935.62, 668.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5486)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 523, 1206)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3120)
[M::mem_pestat] mean and std.dev: (695.87, 609.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4077)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696176 sequences (100000149 bp) in 2.318 CPU sec, 2.499 real sec...
[M::process] read 695910 sequences (100000024 bp) in 1.790 CPU sec, 1.800 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 283384, 18, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 341, 1157)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2983)
[M::mem_pestat] mean and std.dev: (558.12, 620.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3896)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 250, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 780)
[M::mem_pestat] mean and std.dev: (279.01, 143.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 985)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (99, 840, 2019)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5859)
[M::mem_pestat] mean and std.dev: (962.00, 807.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7779)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 408, 1831)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5183)
[M::mem_pestat] mean and std.dev: (832.60, 906.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6859)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696114 reads in 194.949 CPU sec, 6.607 real sec
sorting block 5, #reads = 1076252 mem = 536878261 peak = 853118976
[M::mem_process_seqs] Processed 696024 reads in 124.571 CPU sec, 3.970 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 283511, 27, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 325, 1298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3584)
[M::mem_pestat] mean and std.dev: (759.12, 944.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4727)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 249, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 774)
[M::mem_pestat] mean and std.dev: (277.60, 142.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 977)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 589, 1839)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5237)
[M::mem_pestat] mean and std.dev: (1001.22, 1038.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6936)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (366, 431, 762)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1554)
[M::mem_pestat] mean and std.dev: (476.96, 278.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1950)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 6, #reads = 1076398 mem = 536878774 peak = 853118976
[M::process] read 695330 sequences (100000119 bp) in 2.909 CPU sec, 3.143 real sec...
[M::process] read 695112 sequences (100000090 bp) in 1.750 CPU sec, 1.751 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 282856, 36, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 423, 711)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1663)
[M::mem_pestat] mean and std.dev: (438.58, 288.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2139)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 249, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 768)
[M::mem_pestat] mean and std.dev: (276.98, 141.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 969)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (260, 635, 1662)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4466)
[M::mem_pestat] mean and std.dev: (913.71, 876.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5868)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 348, 939)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2475)
[M::mem_pestat] mean and std.dev: (632.44, 686.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3377)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696176 reads in 198.457 CPU sec, 6.337 real sec
[M::mem_process_seqs] Processed 695910 reads in 132.843 CPU sec, 4.231 real sec
sorting block 7, #reads = 1075876 mem = 536875942 peak = 853118976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 282670, 29, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 517, 3556)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10178)
[M::mem_pestat] mean and std.dev: (1483.17, 1640.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13489)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 250, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (276.94, 140.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 962)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (302, 584, 1065)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2591)
[M::mem_pestat] mean and std.dev: (717.48, 571.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3354)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 316, 921)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2275)
[M::mem_pestat] mean and std.dev: (492.84, 418.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2952)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694990 sequences (100000122 bp) in 2.564 CPU sec, 2.821 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 282838, 26, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 339, 1174)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3102)
[M::mem_pestat] mean and std.dev: (665.63, 720.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4066)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 250, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (276.08, 139.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 958)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 792, 1007)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2731)
[M::mem_pestat] mean and std.dev: (499.95, 435.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3593)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (321, 733, 1852)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4914)
[M::mem_pestat] mean and std.dev: (998.37, 836.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6445)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695112 sequences (100000258 bp) in 1.854 CPU sec, 1.859 real sec...
[M::mem_process_seqs] Processed 695330 reads in 199.342 CPU sec, 6.386 real sec
[M::mem_process_seqs] Processed 695112 reads in 131.304 CPU sec, 4.173 real sec
sorting block 8, #reads = 1074434 mem = 536879631 peak = 853118976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 282617, 24, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 367, 766)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1958)
[M::mem_pestat] mean and std.dev: (432.14, 354.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2554)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 249, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (275.25, 137.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 950)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (99, 371, 1098)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3096)
[M::mem_pestat] mean and std.dev: (595.78, 678.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4095)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (263, 336, 914)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2216)
[M::mem_pestat] mean and std.dev: (536.08, 440.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2867)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695384 sequences (100000299 bp) in 2.940 CPU sec, 3.157 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 282723, 20, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 393, 1207)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3279)
[M::mem_pestat] mean and std.dev: (719.82, 765.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4315)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 249, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (274.54, 137.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 946)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 972, 2877)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8195)
[M::mem_pestat] mean and std.dev: (1308.60, 1387.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10854)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 823, 2593)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7289)
[M::mem_pestat] mean and std.dev: (1203.21, 1229.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9637)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694990 reads in 194.099 CPU sec, 6.251 real sec
[M::process] read 695668 sequences (100000009 bp) in 2.239 CPU sec, 2.242 real sec...
sorting block 9, #reads = 1074641 mem = 536880004 peak = 853118976
[M::mem_process_seqs] Processed 695112 reads in 130.409 CPU sec, 4.130 real sec
sorting block 10, #reads = 1073804 mem = 536880444 peak = 853118976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 282680, 24, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (263, 510, 623)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1343)
[M::mem_pestat] mean and std.dev: (493.91, 288.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1703)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 744)
[M::mem_pestat] mean and std.dev: (272.23, 135.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 937)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (84, 348, 1406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4050)
[M::mem_pestat] mean and std.dev: (646.59, 761.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5372)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (261, 493, 810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1908)
[M::mem_pestat] mean and std.dev: (395.77, 211.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2457)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695892 sequences (100000199 bp) in 2.841 CPU sec, 3.051 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 283452, 24, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (255, 625, 3344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9522)
[M::mem_pestat] mean and std.dev: (1580.78, 2145.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12611)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 747)
[M::mem_pestat] mean and std.dev: (273.13, 136.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 941)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (407, 733, 3073)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8405)
[M::mem_pestat] mean and std.dev: (1240.45, 1529.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11071)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 369, 2845)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8065)
[M::mem_pestat] mean and std.dev: (573.97, 652.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10675)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695596 sequences (100000068 bp) in 2.048 CPU sec, 2.053 real sec...
[M::mem_process_seqs] Processed 695384 reads in 196.309 CPU sec, 6.508 real sec
[M::mem_process_seqs] Processed 695668 reads in 128.724 CPU sec, 4.078 real sec
sorting block 11, #reads = 1074613 mem = 536877360 peak = 853118976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 283321, 10, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (263, 556, 1858)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5048)
[M::mem_pestat] mean and std.dev: (896.76, 1071.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6643)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 744)
[M::mem_pestat] mean and std.dev: (272.54, 136.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 937)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (578, 1834, 2566)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6542)
[M::mem_pestat] mean and std.dev: (1705.80, 1235.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8530)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 425, 2346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6708)
[M::mem_pestat] mean and std.dev: (1053.59, 1229.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8889)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695638 sequences (100000081 bp) in 3.256 CPU sec, 3.507 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 282596, 20, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 234, 699)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1803)
[M::mem_pestat] mean and std.dev: (388.19, 357.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2355)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (273.57, 136.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 945)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (468, 769, 1658)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4038)
[M::mem_pestat] mean and std.dev: (965.32, 694.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5228)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 301, 1158)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3160)
[M::mem_pestat] mean and std.dev: (531.50, 592.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4161)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695892 reads in 193.868 CPU sec, 6.180 real sec
[M::process] read 694856 sequences (100000037 bp) in 2.456 CPU sec, 2.490 real sec...
[M::mem_process_seqs] Processed 695596 reads in 133.320 CPU sec, 4.453 real sec
sorting block 12, #reads = 1074129 mem = 536878924 peak = 853118976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 282818, 21, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (270, 444, 1685)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4515)
[M::mem_pestat] mean and std.dev: (758.58, 664.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5930)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 250, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (275.36, 138.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (321, 409, 1402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3564)
[M::mem_pestat] mean and std.dev: (837.25, 710.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4645)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 458, 561)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1271)
[M::mem_pestat] mean and std.dev: (377.19, 238.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1626)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697190 sequences (100000048 bp) in 3.320 CPU sec, 3.606 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 282737, 23, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 294, 491)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1003)
[M::mem_pestat] mean and std.dev: (322.67, 147.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1259)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 252, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 767)
[M::mem_pestat] mean and std.dev: (278.24, 139.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 967)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (371, 844, 2220)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5918)
[M::mem_pestat] mean and std.dev: (1134.65, 1003.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7767)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 391, 1802)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5060)
[M::mem_pestat] mean and std.dev: (895.09, 1071.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6689)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700800 sequences (100000295 bp) in 1.948 CPU sec, 1.951 real sec...
[M::mem_process_seqs] Processed 695638 reads in 203.033 CPU sec, 6.684 real sec
sorting block 13, #reads = 1072380 mem = 536880648 peak = 853118976
[M::mem_process_seqs] Processed 694856 reads in 131.399 CPU sec, 4.164 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 283003, 14, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 221, 881)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2339)
[M::mem_pestat] mean and std.dev: (509.28, 578.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3068)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 245, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (271.86, 137.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 947)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (745, 1339, 2098)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4804)
[M::mem_pestat] mean and std.dev: (1308.62, 765.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6157)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 411, 2029)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5719)
[M::mem_pestat] mean and std.dev: (906.26, 852.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7564)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 14, #reads = 1071005 mem = 536877605 peak = 853118976
[M::process] read 700116 sequences (100000101 bp) in 3.164 CPU sec, 3.393 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 284664, 34, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 270, 614)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1468)
[M::mem_pestat] mean and std.dev: (424.39, 376.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1929)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 233, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 720)
[M::mem_pestat] mean and std.dev: (261.78, 134.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 908)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (589, 614, 1402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3028)
[M::mem_pestat] mean and std.dev: (818.24, 554.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3841)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 252, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1000)
[M::mem_pestat] mean and std.dev: (307.94, 221.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1281)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697190 reads in 191.282 CPU sec, 6.083 real sec
[M::process] read 699078 sequences (100000262 bp) in 2.345 CPU sec, 2.365 real sec...
[M::mem_process_seqs] Processed 700800 reads in 133.397 CPU sec, 4.228 real sec
sorting block 15, #reads = 1073547 mem = 536889623 peak = 853118976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 284658, 11, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 421, 1068)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2918)
[M::mem_pestat] mean and std.dev: (641.15, 620.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3843)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 236, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 734)
[M::mem_pestat] mean and std.dev: (265.22, 136.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 926)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 406, 622)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1456)
[M::mem_pestat] mean and std.dev: (483.73, 329.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1873)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (276, 452, 723)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1617)
[M::mem_pestat] mean and std.dev: (471.49, 281.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2064)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698578 sequences (100000021 bp) in 2.791 CPU sec, 2.983 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 284596, 16, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 521, 1537)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4235)
[M::mem_pestat] mean and std.dev: (873.61, 878.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5584)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 239, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 741)
[M::mem_pestat] mean and std.dev: (267.14, 136.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 935)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (270, 906, 2256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6228)
[M::mem_pestat] mean and std.dev: (1067.47, 1153.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8214)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (270, 469, 1253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3219)
[M::mem_pestat] mean and std.dev: (691.12, 634.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4202)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700116 reads in 183.574 CPU sec, 5.845 real sec
[M::process] read 698482 sequences (100000142 bp) in 2.581 CPU sec, 2.620 real sec...
[M::mem_process_seqs] Processed 699078 reads in 121.843 CPU sec, 3.848 real sec
sorting block 16, #reads = 1079589 mem = 536877390 peak = 853118976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 284523, 37, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 275, 760)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1908)
[M::mem_pestat] mean and std.dev: (388.80, 342.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2482)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 240, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (269.39, 138.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 948)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (108, 324, 1047)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2925)
[M::mem_pestat] mean and std.dev: (500.26, 553.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3864)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 639, 781)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1925)
[M::mem_pestat] mean and std.dev: (597.23, 423.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2497)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697958 sequences (100000273 bp) in 3.308 CPU sec, 3.543 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 284352, 20, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 420, 679)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1679)
[M::mem_pestat] mean and std.dev: (451.52, 301.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2179)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 242, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (270.81, 139.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 956)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (755, 1816, 7054)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 19652)
[M::mem_pestat] mean and std.dev: (3322.80, 2946.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 25951)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 294, 1609)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4397)
[M::mem_pestat] mean and std.dev: (691.25, 759.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5791)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698578 reads in 184.135 CPU sec, 6.074 real sec
[M::mem_process_seqs] Processed 698482 reads in 125.332 CPU sec, 3.959 real sec
sorting block 17, #reads = 1079359 mem = 536879023 peak = 853118976
[M::process] read 697670 sequences (100000039 bp) in 2.868 CPU sec, 3.064 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 284485, 22, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 425, 1067)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2883)
[M::mem_pestat] mean and std.dev: (526.83, 511.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3791)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 244, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (272.83, 140.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 965)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (89, 201, 870)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2432)
[M::mem_pestat] mean and std.dev: (377.00, 448.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3213)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 1042, 1601)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4325)
[M::mem_pestat] mean and std.dev: (779.96, 560.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5687)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697200 sequences (100000040 bp) in 2.859 CPU sec, 3.104 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 284279, 22, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 415, 708)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1692)
[M::mem_pestat] mean and std.dev: (410.08, 268.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2184)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 244, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (273.62, 140.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 966)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 660, 1523)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4135)
[M::mem_pestat] mean and std.dev: (1071.45, 1097.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5462)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 376, 1084)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2822)
[M::mem_pestat] mean and std.dev: (590.65, 454.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3691)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697958 reads in 183.418 CPU sec, 5.851 real sec
sorting block 18, #reads = 1078234 mem = 536878048 peak = 853118976
[M::mem_process_seqs] Processed 697670 reads in 123.268 CPU sec, 3.889 real sec
[M::process] read 696862 sequences (100000105 bp) in 3.332 CPU sec, 3.567 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 283801, 40, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (356, 503, 1605)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4103)
[M::mem_pestat] mean and std.dev: (912.56, 837.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5352)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 246, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 769)
[M::mem_pestat] mean and std.dev: (275.25, 141.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 971)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (909, 1648, 2065)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4377)
[M::mem_pestat] mean and std.dev: (1371.16, 803.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5533)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 333, 654)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1576)
[M::mem_pestat] mean and std.dev: (395.31, 289.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2037)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 19, #reads = 1077874 mem = 536878555 peak = 853118976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 283308, 22, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 317, 390)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 844)
[M::mem_pestat] mean and std.dev: (250.00, 124.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1071)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 696316 sequences (100000139 bp) in 3.003 CPU sec, 3.222 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (163, 247, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 769)
[M::mem_pestat] mean and std.dev: (275.63, 141.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 971)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 542, 1142)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3012)
[M::mem_pestat] mean and std.dev: (683.62, 693.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3947)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (261, 399, 1288)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3342)
[M::mem_pestat] mean and std.dev: (703.39, 685.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4369)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697200 reads in 182.524 CPU sec, 5.856 real sec
[M::mem_process_seqs] Processed 696862 reads in 123.441 CPU sec, 3.907 real sec
sorting block 20, #reads = 1077195 mem = 536884848 peak = 853118976
[M::process] read 696312 sequences (100000105 bp) in 3.195 CPU sec, 3.443 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 283852, 22, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (297, 546, 815)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1851)
[M::mem_pestat] mean and std.dev: (489.48, 317.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2369)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 249, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 780)
[M::mem_pestat] mean and std.dev: (278.32, 142.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 985)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (357, 927, 1991)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5259)
[M::mem_pestat] mean and std.dev: (1031.09, 733.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6893)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 269, 868)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2232)
[M::mem_pestat] mean and std.dev: (401.45, 323.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2914)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 283778, 25, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (375, 645, 1666)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4248)
[M::mem_pestat] mean and std.dev: (862.50, 799.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5539)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 250, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 777)
[M::mem_pestat] mean and std.dev: (278.65, 143.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 981)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 309, 821)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2009)
[M::mem_pestat] mean and std.dev: (487.35, 420.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2603)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 886, 1951)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5345)
[M::mem_pestat] mean and std.dev: (1390.98, 1361.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7042)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695908 sequences (100000276 bp) in 3.122 CPU sec, 3.346 real sec...
[M::mem_process_seqs] Processed 696316 reads in 187.637 CPU sec, 5.987 real sec
[M::mem_process_seqs] Processed 696312 reads in 125.170 CPU sec, 3.959 real sec
sorting block 21, #reads = 1076302 mem = 536881368 peak = 853118976
[M::process] read 695166 sequences (100000060 bp) in 3.201 CPU sec, 3.469 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 282968, 28, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 465, 2203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6199)
[M::mem_pestat] mean and std.dev: (841.59, 1057.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8197)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 250, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 775)
[M::mem_pestat] mean and std.dev: (278.49, 142.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 978)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (57, 540, 2535)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7491)
[M::mem_pestat] mean and std.dev: (1293.46, 1737.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9969)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 318, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 922)
[M::mem_pestat] mean and std.dev: (332.50, 137.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1156)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695522 sequences (100000279 bp) in 2.762 CPU sec, 2.919 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 282912, 24, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 386, 1028)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2704)
[M::mem_pestat] mean and std.dev: (584.06, 576.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3542)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 252, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 784)
[M::mem_pestat] mean and std.dev: (280.87, 143.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 990)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (420, 478, 1301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3063)
[M::mem_pestat] mean and std.dev: (733.91, 482.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3944)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 260, 548)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1218)
[M::mem_pestat] mean and std.dev: (304.40, 196.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1553)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695908 reads in 187.545 CPU sec, 5.979 real sec
sorting block 22, #reads = 1077119 mem = 536879155 peak = 853118976
[M::mem_process_seqs] Processed 695166 reads in 126.503 CPU sec, 3.995 real sec
[M::process] read 695104 sequences (100000252 bp) in 2.964 CPU sec, 3.163 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 282754, 27, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 321, 1131)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2899)
[M::mem_pestat] mean and std.dev: (595.26, 490.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3783)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 249, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (274.78, 137.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 950)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (254, 493, 764)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1784)
[M::mem_pestat] mean and std.dev: (490.88, 358.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2294)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 344, 1042)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2702)
[M::mem_pestat] mean and std.dev: (571.60, 431.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3532)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 23, #reads = 1075131 mem = 536879495 peak = 853118976
[M::process] read 695334 sequences (100000184 bp) in 2.900 CPU sec, 3.092 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 282841, 40, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 338, 734)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1848)
[M::mem_pestat] mean and std.dev: (501.05, 426.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2405)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 251, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (277.15, 139.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 959)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (95, 269, 935)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2615)
[M::mem_pestat] mean and std.dev: (526.82, 555.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3455)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 461, 992)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2594)
[M::mem_pestat] mean and std.dev: (597.38, 455.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3395)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695522 reads in 189.145 CPU sec, 6.015 real sec
[M::mem_process_seqs] Processed 695104 reads in 124.643 CPU sec, 3.930 real sec
[M::process] read 695616 sequences (100000046 bp) in 2.562 CPU sec, 2.703 real sec...
sorting block 24, #reads = 1074915 mem = 536884545 peak = 853118976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 282199, 24, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 566, 1605)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4437)
[M::mem_pestat] mean and std.dev: (939.62, 929.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5853)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 249, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (275.14, 137.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (384, 992, 4091)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11505)
[M::mem_pestat] mean and std.dev: (1870.58, 2101.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 15212)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (289, 618, 1541)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4045)
[M::mem_pestat] mean and std.dev: (874.98, 841.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5297)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695660 sequences (100000128 bp) in 3.026 CPU sec, 3.245 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 282854, 19, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 318, 1212)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3202)
[M::mem_pestat] mean and std.dev: (568.10, 633.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4197)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (274.24, 137.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 953)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (123, 247, 749)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2001)
[M::mem_pestat] mean and std.dev: (431.89, 408.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2627)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 327, 541)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1123)
[M::mem_pestat] mean and std.dev: (380.59, 197.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1414)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695334 reads in 186.138 CPU sec, 5.922 real sec
[M::mem_process_seqs] Processed 695616 reads in 125.315 CPU sec, 3.956 real sec
[M::process] read 695280 sequences (100000051 bp) in 2.391 CPU sec, 2.475 real sec...
sorting block 25, #reads = 1074354 mem = 536879629 peak = 853118976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 283101, 37, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 316, 1612)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4430)
[M::mem_pestat] mean and std.dev: (733.78, 993.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5839)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (274.12, 137.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 383, 986)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2532)
[M::mem_pestat] mean and std.dev: (582.34, 544.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3305)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 350, 939)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2417)
[M::mem_pestat] mean and std.dev: (533.24, 531.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3156)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695340 sequences (100000035 bp) in 3.328 CPU sec, 3.555 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 282563, 18, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (246, 382, 708)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1632)
[M::mem_pestat] mean and std.dev: (429.56, 271.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2094)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 249, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (276.26, 139.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 962)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 636, 965)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2569)
[M::mem_pestat] mean and std.dev: (548.94, 477.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3371)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 431, 2457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6983)
[M::mem_pestat] mean and std.dev: (1082.11, 1076.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9246)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695660 reads in 186.734 CPU sec, 5.943 real sec
[M::process] read 696170 sequences (100000047 bp) in 2.254 CPU sec, 2.309 real sec...
sorting block 26, #reads = 1074930 mem = 536875784 peak = 853118976
[M::mem_process_seqs] Processed 695280 reads in 126.718 CPU sec, 3.998 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 282377, 27, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 333, 1170)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3088)
[M::mem_pestat] mean and std.dev: (630.34, 624.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4047)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (273.76, 136.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 945)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 442, 898)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2198)
[M::mem_pestat] mean and std.dev: (507.40, 391.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2848)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (287, 357, 1228)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3110)
[M::mem_pestat] mean and std.dev: (714.41, 683.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4051)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 27, #reads = 1073160 mem = 536880530 peak = 853118976
[M::process] read 695758 sequences (100000113 bp) in 3.066 CPU sec, 3.280 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283501, 26, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (263, 1076, 2414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6716)
[M::mem_pestat] mean and std.dev: (1216.73, 1362.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8867)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 246, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 752)
[M::mem_pestat] mean and std.dev: (272.97, 137.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 948)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 622, 1805)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5077)
[M::mem_pestat] mean and std.dev: (996.28, 1193.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6713)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (305, 728, 1061)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2573)
[M::mem_pestat] mean and std.dev: (650.97, 513.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3329)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695760 sequences (100000221 bp) in 1.939 CPU sec, 1.948 real sec...
[M::mem_process_seqs] Processed 695340 reads in 197.094 CPU sec, 6.456 real sec
[M::mem_process_seqs] Processed 696170 reads in 128.697 CPU sec, 4.129 real sec
sorting block 28, #reads = 1073655 mem = 536880309 peak = 853118976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 282963, 24, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (131, 225, 853)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2297)
[M::mem_pestat] mean and std.dev: (492.76, 556.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3019)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 249, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 762)
[M::mem_pestat] mean and std.dev: (275.37, 139.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 961)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (355, 912, 1795)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4675)
[M::mem_pestat] mean and std.dev: (713.84, 535.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6115)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 470, 1262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3380)
[M::mem_pestat] mean and std.dev: (813.31, 830.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4439)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697478 sequences (100000222 bp) in 3.243 CPU sec, 3.471 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 283191, 32, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (270, 524, 920)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2220)
[M::mem_pestat] mean and std.dev: (612.14, 559.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2870)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 249, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 771)
[M::mem_pestat] mean and std.dev: (276.94, 140.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 973)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (323, 562, 1452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3710)
[M::mem_pestat] mean and std.dev: (655.79, 636.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4839)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 332, 727)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1785)
[M::mem_pestat] mean and std.dev: (403.77, 308.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2314)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695758 reads in 198.808 CPU sec, 6.376 real sec
[M::process] read 701700 sequences (100000002 bp) in 2.216 CPU sec, 2.212 real sec...
[M::mem_process_seqs] Processed 695760 reads in 133.142 CPU sec, 4.215 real sec
sorting block 29, #reads = 1073611 mem = 536884064 peak = 853118976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 283873, 25, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 272, 563)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1353)
[M::mem_pestat] mean and std.dev: (358.17, 284.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1748)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 244, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (271.21, 137.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 946)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 603, 719)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1791)
[M::mem_pestat] mean and std.dev: (564.08, 421.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2327)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 362, 628)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1548)
[M::mem_pestat] mean and std.dev: (446.58, 332.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2008)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701474 sequences (100000030 bp) in 2.951 CPU sec, 3.169 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 285038, 18, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (286, 479, 1721)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4591)
[M::mem_pestat] mean and std.dev: (598.96, 581.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6026)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 230, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 716)
[M::mem_pestat] mean and std.dev: (259.21, 132.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 903)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (374, 894, 1432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3548)
[M::mem_pestat] mean and std.dev: (873.56, 553.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4606)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (276, 535, 2565)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7143)
[M::mem_pestat] mean and std.dev: (997.21, 1074.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9432)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701062 sequences (100000105 bp) in 2.057 CPU sec, 2.052 real sec...
[M::mem_process_seqs] Processed 697478 reads in 195.351 CPU sec, 6.234 real sec
[M::mem_process_seqs] Processed 701700 reads in 129.982 CPU sec, 4.121 real sec
sorting block 30, #reads = 1072035 mem = 536878632 peak = 853118976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 285313, 22, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 342, 986)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2602)
[M::mem_pestat] mean and std.dev: (643.28, 722.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3534)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 232, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 722)
[M::mem_pestat] mean and std.dev: (260.75, 134.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 911)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (92, 384, 2104)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6128)
[M::mem_pestat] mean and std.dev: (1062.50, 1511.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8140)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 335, 1318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3638)
[M::mem_pestat] mean and std.dev: (613.06, 604.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4798)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 31, #reads = 1076506 mem = 536878355 peak = 853118976
[M::process] read 700430 sequences (100000162 bp) in 3.253 CPU sec, 3.480 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 285122, 27, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 383, 1448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4006)
[M::mem_pestat] mean and std.dev: (744.54, 707.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5285)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 233, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 723)
[M::mem_pestat] mean and std.dev: (261.26, 133.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 912)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (357, 1232, 2849)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7833)
[M::mem_pestat] mean and std.dev: (1731.52, 1823.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10325)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 361, 1415)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3773)
[M::mem_pestat] mean and std.dev: (670.70, 588.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4952)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701474 reads in 187.610 CPU sec, 5.978 real sec
[M::mem_process_seqs] Processed 701062 reads in 124.469 CPU sec, 3.930 real sec
[M::process] read 700308 sequences (100000123 bp) in 2.648 CPU sec, 2.727 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 284959, 7, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 346, 1088)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2924)
[M::mem_pestat] mean and std.dev: (537.98, 476.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3842)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 234, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 730)
[M::mem_pestat] mean and std.dev: (263.80, 135.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 921)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 323, 874)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2314)
[M::mem_pestat] mean and std.dev: (451.40, 363.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3034)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 32, #reads = 1078812 mem = 536880264 peak = 853118976
[M::process] read 699274 sequences (100000102 bp) in 3.631 CPU sec, 3.904 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 284624, 23, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (320, 387, 2227)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6041)
[M::mem_pestat] mean and std.dev: (1081.73, 1189.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7948)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 236, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 737)
[M::mem_pestat] mean and std.dev: (265.40, 137.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 930)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (74, 241, 1482)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4298)
[M::mem_pestat] mean and std.dev: (786.35, 967.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5706)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (305, 330, 483)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 839)
[M::mem_pestat] mean and std.dev: (321.96, 119.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1017)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700430 reads in 188.817 CPU sec, 6.021 real sec
[M::mem_process_seqs] Processed 700308 reads in 127.106 CPU sec, 4.019 real sec
[M::process] read 699138 sequences (100000015 bp) in 2.506 CPU sec, 2.632 real sec...
sorting block 33, #reads = 1078538 mem = 536878999 peak = 853118976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 284523, 28, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (343, 611, 1235)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3019)
[M::mem_pestat] mean and std.dev: (662.68, 484.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3911)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 238, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 741)
[M::mem_pestat] mean and std.dev: (266.85, 136.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 935)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (103, 249, 1281)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3637)
[M::mem_pestat] mean and std.dev: (795.18, 1025.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4898)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 462, 1498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4084)
[M::mem_pestat] mean and std.dev: (714.65, 754.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5377)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698188 sequences (100000167 bp) in 3.196 CPU sec, 3.421 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 284562, 21, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 511, 1106)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2966)
[M::mem_pestat] mean and std.dev: (671.44, 584.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3896)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 239, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 747)
[M::mem_pestat] mean and std.dev: (268.22, 138.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 943)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (56, 324, 834)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2390)
[M::mem_pestat] mean and std.dev: (646.62, 693.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3419)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (386, 979, 1086)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2486)
[M::mem_pestat] mean and std.dev: (786.94, 508.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3186)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699274 reads in 188.298 CPU sec, 6.002 real sec
[M::mem_process_seqs] Processed 699138 reads in 126.557 CPU sec, 3.998 real sec
[M::process] read 697938 sequences (100000151 bp) in 2.576 CPU sec, 2.706 real sec...
sorting block 34, #reads = 1077780 mem = 536879316 peak = 853118976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 284725, 20, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 457, 1307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3453)
[M::mem_pestat] mean and std.dev: (893.50, 885.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4526)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 242, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (271.65, 140.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 957)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 602, 1032)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2646)
[M::mem_pestat] mean and std.dev: (657.00, 580.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3453)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (266, 715, 1873)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5087)
[M::mem_pestat] mean and std.dev: (849.30, 902.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6694)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697606 sequences (100000072 bp) in 3.431 CPU sec, 3.690 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 283969, 18, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 265, 911)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2335)
[M::mem_pestat] mean and std.dev: (429.33, 377.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3047)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 243, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (271.98, 139.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 957)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (56, 451, 733)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2087)
[M::mem_pestat] mean and std.dev: (468.24, 500.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2764)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 270, 559)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1295)
[M::mem_pestat] mean and std.dev: (310.50, 183.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1663)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698188 reads in 189.347 CPU sec, 6.031 real sec
sorting block 35, #reads = 1078402 mem = 536878361 peak = 853118976
[M::mem_process_seqs] Processed 697938 reads in 129.835 CPU sec, 4.101 real sec
[M::process] read 697478 sequences (100000173 bp) in 2.810 CPU sec, 2.963 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 283970, 21, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (260, 443, 1778)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4814)
[M::mem_pestat] mean and std.dev: (964.19, 957.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6332)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 245, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 771)
[M::mem_pestat] mean and std.dev: (275.08, 142.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 974)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (335, 1021, 1671)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4343)
[M::mem_pestat] mean and std.dev: (1009.65, 910.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5679)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 290, 501)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1073)
[M::mem_pestat] mean and std.dev: (340.46, 202.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1359)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 36, #reads = 1078373 mem = 536880381 peak = 853118976
[M::process] read 696848 sequences (100000233 bp) in 3.512 CPU sec, 3.729 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 284172, 26, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 415, 580)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1416)
[M::mem_pestat] mean and std.dev: (441.98, 331.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1834)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 245, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 771)
[M::mem_pestat] mean and std.dev: (274.99, 142.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 974)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (431, 752, 1330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3128)
[M::mem_pestat] mean and std.dev: (912.92, 725.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4027)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 347, 1036)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2626)
[M::mem_pestat] mean and std.dev: (560.31, 486.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3421)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697606 reads in 192.192 CPU sec, 6.130 real sec
[M::mem_process_seqs] Processed 697478 reads in 130.986 CPU sec, 4.147 real sec
[M::process] read 696740 sequences (100000196 bp) in 2.778 CPU sec, 2.960 real sec...
sorting block 37, #reads = 1076403 mem = 536880541 peak = 853118976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 283741, 21, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (132, 230, 586)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1494)
[M::mem_pestat] mean and std.dev: (302.42, 234.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1948)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 247, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 772)
[M::mem_pestat] mean and std.dev: (276.30, 142.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 975)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (446, 727, 2581)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6851)
[M::mem_pestat] mean and std.dev: (1273.05, 1415.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8986)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 303, 807)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1999)
[M::mem_pestat] mean and std.dev: (462.23, 352.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2595)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697474 sequences (100000296 bp) in 3.403 CPU sec, 3.630 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 283525, 17, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 363, 771)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1901)
[M::mem_pestat] mean and std.dev: (581.41, 568.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2855)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 247, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 772)
[M::mem_pestat] mean and std.dev: (276.32, 142.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 975)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 291, 1427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3915)
[M::mem_pestat] mean and std.dev: (726.00, 751.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5159)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (306, 644, 2158)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5862)
[M::mem_pestat] mean and std.dev: (1255.45, 1267.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7714)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696848 reads in 189.208 CPU sec, 6.037 real sec
[M::mem_process_seqs] Processed 696740 reads in 128.135 CPU sec, 4.050 real sec
sorting block 38, #reads = 1076028 mem = 536885691 peak = 853118976
[M::process] read 697546 sequences (100000016 bp) in 2.977 CPU sec, 3.165 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 283602, 18, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 308, 689)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1621)
[M::mem_pestat] mean and std.dev: (337.26, 205.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2087)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 241, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 732)
[M::mem_pestat] mean and std.dev: (267.65, 134.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 922)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (263, 977, 1441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3797)
[M::mem_pestat] mean and std.dev: (1003.50, 870.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4975)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 476, 826)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2128)
[M::mem_pestat] mean and std.dev: (539.86, 448.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2779)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696164 sequences (100000054 bp) in 3.168 CPU sec, 3.394 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 283583, 20, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 335, 648)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1486)
[M::mem_pestat] mean and std.dev: (399.73, 272.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1905)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 242, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 744)
[M::mem_pestat] mean and std.dev: (269.92, 137.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 938)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (884, 1158, 1435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2537)
[M::mem_pestat] mean and std.dev: (951.05, 541.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3118)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 379, 620)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1358)
[M::mem_pestat] mean and std.dev: (375.97, 201.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1727)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697474 reads in 190.645 CPU sec, 6.073 real sec
sorting block 39, #reads = 1076273 mem = 536879397 peak = 853118976
[M::mem_process_seqs] Processed 697546 reads in 129.207 CPU sec, 4.078 real sec
[M::process] read 695510 sequences (100000288 bp) in 2.994 CPU sec, 3.173 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 283741, 25, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 449, 850)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2062)
[M::mem_pestat] mean and std.dev: (507.57, 419.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2668)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 249, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 762)
[M::mem_pestat] mean and std.dev: (275.75, 140.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 961)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (474, 652, 1126)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2430)
[M::mem_pestat] mean and std.dev: (672.04, 406.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3082)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 366, 1084)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2820)
[M::mem_pestat] mean and std.dev: (672.97, 572.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3688)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 40, #reads = 1076074 mem = 536885744 peak = 853118976
[M::process] read 695794 sequences (100000052 bp) in 3.121 CPU sec, 3.348 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 282697, 17, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 390, 1630)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4512)
[M::mem_pestat] mean and std.dev: (893.78, 1031.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5953)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 250, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 769)
[M::mem_pestat] mean and std.dev: (277.89, 141.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 970)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (272, 469, 3244)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9188)
[M::mem_pestat] mean and std.dev: (1482.59, 1483.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12160)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 372, 989)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2523)
[M::mem_pestat] mean and std.dev: (575.00, 565.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3290)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696164 reads in 189.972 CPU sec, 6.057 real sec
[M::mem_process_seqs] Processed 695510 reads in 129.778 CPU sec, 4.108 real sec
[M::process] read 695496 sequences (100000233 bp) in 2.532 CPU sec, 2.665 real sec...
sorting block 41, #reads = 1075723 mem = 536881455 peak = 853118976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 283395, 22, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 347, 767)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1849)
[M::mem_pestat] mean and std.dev: (411.03, 329.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2390)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 250, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 768)
[M::mem_pestat] mean and std.dev: (277.17, 140.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 969)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (272, 634, 1120)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2816)
[M::mem_pestat] mean and std.dev: (758.55, 559.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3664)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 322, 970)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2408)
[M::mem_pestat] mean and std.dev: (577.20, 581.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3127)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695832 sequences (100000069 bp) in 3.084 CPU sec, 3.307 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 283072, 21, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (252, 532, 1286)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3354)
[M::mem_pestat] mean and std.dev: (872.04, 821.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4388)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 249, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 766)
[M::mem_pestat] mean and std.dev: (277.25, 141.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 966)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (131, 278, 1670)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4748)
[M::mem_pestat] mean and std.dev: (801.15, 983.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6287)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 337, 864)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2198)
[M::mem_pestat] mean and std.dev: (528.39, 530.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2865)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695794 reads in 189.988 CPU sec, 6.076 real sec
[M::mem_process_seqs] Processed 695496 reads in 129.662 CPU sec, 4.100 real sec
[M::process] read 695680 sequences (100000207 bp) in 2.698 CPU sec, 2.826 real sec...
sorting block 42, #reads = 1073891 mem = 536881659 peak = 853118976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 283261, 21, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 333, 1096)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2850)
[M::mem_pestat] mean and std.dev: (597.87, 507.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3727)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 249, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 768)
[M::mem_pestat] mean and std.dev: (276.54, 140.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 969)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 1108, 2192)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6098)
[M::mem_pestat] mean and std.dev: (1120.37, 1251.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8051)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 245, 576)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1368)
[M::mem_pestat] mean and std.dev: (309.93, 209.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1764)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696560 sequences (100000144 bp) in 3.306 CPU sec, 3.504 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 283297, 14, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 358, 766)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1956)
[M::mem_pestat] mean and std.dev: (399.27, 299.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2551)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 250, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (276.76, 140.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 962)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (98, 419, 886)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2462)
[M::mem_pestat] mean and std.dev: (314.55, 248.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3250)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 364, 894)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2348)
[M::mem_pestat] mean and std.dev: (560.18, 466.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3075)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695832 reads in 196.728 CPU sec, 6.302 real sec
[M::mem_process_seqs] Processed 695680 reads in 132.833 CPU sec, 4.197 real sec
sorting block 43, #reads = 1073622 mem = 536878034 peak = 853118976
[M::process] read 695036 sequences (100000227 bp) in 2.793 CPU sec, 2.924 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 282858, 27, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 295, 1222)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3364)
[M::mem_pestat] mean and std.dev: (490.46, 549.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4435)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 247, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (274.67, 140.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 960)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (313, 498, 1152)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2830)
[M::mem_pestat] mean and std.dev: (581.80, 507.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3669)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 334, 644)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1588)
[M::mem_pestat] mean and std.dev: (405.91, 290.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2060)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 44, #reads = 1073344 mem = 536881599 peak = 853118976
[M::process] read 698808 sequences (100000050 bp) in 3.027 CPU sec, 3.263 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 282966, 30, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 465, 1329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3629)
[M::mem_pestat] mean and std.dev: (623.71, 614.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4779)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 252, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 782)
[M::mem_pestat] mean and std.dev: (280.70, 143.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 987)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 465, 514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1226)
[M::mem_pestat] mean and std.dev: (349.59, 206.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1582)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 429, 1357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3573)
[M::mem_pestat] mean and std.dev: (520.47, 467.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4681)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696560 reads in 198.303 CPU sec, 6.339 real sec
[M::process] read 701004 sequences (100000193 bp) in 2.197 CPU sec, 2.259 real sec...
[M::mem_process_seqs] Processed 695036 reads in 133.383 CPU sec, 4.214 real sec
sorting block 45, #reads = 1071747 mem = 536892785 peak = 853118976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 284013, 25, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 328, 924)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2458)
[M::mem_pestat] mean and std.dev: (483.33, 410.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3225)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 239, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 742)
[M::mem_pestat] mean and std.dev: (267.98, 137.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 936)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (902, 1771, 2381)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5339)
[M::mem_pestat] mean and std.dev: (1641.38, 1247.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6818)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 296, 611)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1329)
[M::mem_pestat] mean and std.dev: (401.79, 307.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1688)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700350 sequences (100000109 bp) in 3.084 CPU sec, 3.314 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 284997, 19, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 362, 972)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2414)
[M::mem_pestat] mean and std.dev: (638.19, 531.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3135)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 232, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 720)
[M::mem_pestat] mean and std.dev: (260.79, 133.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 908)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 226, 792)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1942)
[M::mem_pestat] mean and std.dev: (478.26, 435.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2517)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 497, 1192)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3306)
[M::mem_pestat] mean and std.dev: (714.50, 620.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4363)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699888 sequences (100000123 bp) in 2.179 CPU sec, 2.183 real sec...
[M::mem_process_seqs] Processed 698808 reads in 197.828 CPU sec, 6.515 real sec
[M::mem_process_seqs] Processed 701004 reads in 125.954 CPU sec, 4.137 real sec
sorting block 46, #reads = 1073537 mem = 536878914 peak = 853118976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (18, 284715, 17, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 186, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (215.75, 121.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 234, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 727)
[M::mem_pestat] mean and std.dev: (262.80, 134.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 917)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 484, 1841)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5105)
[M::mem_pestat] mean and std.dev: (846.62, 772.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6737)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (276, 412, 954)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2310)
[M::mem_pestat] mean and std.dev: (587.80, 567.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2988)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699780 sequences (100000107 bp) in 3.059 CPU sec, 3.266 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 285324, 25, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 426, 1227)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3219)
[M::mem_pestat] mean and std.dev: (675.81, 619.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4215)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 728)
[M::mem_pestat] mean and std.dev: (263.55, 134.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 918)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 513, 1672)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4516)
[M::mem_pestat] mean and std.dev: (839.00, 862.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5938)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (260, 487, 672)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1496)
[M::mem_pestat] mean and std.dev: (424.91, 229.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1908)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700350 reads in 182.585 CPU sec, 5.957 real sec
[M::process] read 700216 sequences (100000129 bp) in 2.357 CPU sec, 2.395 real sec...
[M::mem_process_seqs] Processed 699888 reads in 122.184 CPU sec, 4.106 real sec
sorting block 47, #reads = 1080828 mem = 536880477 peak = 853118976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 284919, 25, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 300, 1373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3773)
[M::mem_pestat] mean and std.dev: (684.71, 695.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4973)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 731)
[M::mem_pestat] mean and std.dev: (264.38, 135.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 922)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (380, 541, 1683)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4289)
[M::mem_pestat] mean and std.dev: (529.05, 436.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5592)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 427, 499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1045)
[M::mem_pestat] mean and std.dev: (342.09, 152.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1318)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 48, #reads = 1079373 mem = 536878555 peak = 853118976
[M::process] read 699474 sequences (100000276 bp) in 2.899 CPU sec, 3.115 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 284829, 12, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (296, 723, 1525)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3983)
[M::mem_pestat] mean and std.dev: (940.97, 824.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5212)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 234, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 730)
[M::mem_pestat] mean and std.dev: (263.60, 135.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 921)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (497, 923, 1301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2909)
[M::mem_pestat] mean and std.dev: (787.17, 421.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3713)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (314, 650, 873)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1991)
[M::mem_pestat] mean and std.dev: (576.67, 383.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2550)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699780 reads in 182.611 CPU sec, 6.057 real sec
[M::process] read 699492 sequences (100000052 bp) in 2.384 CPU sec, 2.435 real sec...
[M::mem_process_seqs] Processed 700216 reads in 124.433 CPU sec, 4.136 real sec
sorting block 49, #reads = 1079532 mem = 536882416 peak = 853118976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (18, 284539, 22, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 297, 1091)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2971)
[M::mem_pestat] mean and std.dev: (596.33, 526.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3911)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 238, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 744)
[M::mem_pestat] mean and std.dev: (267.19, 137.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 939)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (78, 388, 634)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1746)
[M::mem_pestat] mean and std.dev: (341.24, 274.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2302)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 494, 995)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2563)
[M::mem_pestat] mean and std.dev: (555.86, 372.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3347)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698764 sequences (100000172 bp) in 3.125 CPU sec, 3.343 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 284827, 22, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 330, 942)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2534)
[M::mem_pestat] mean and std.dev: (622.58, 653.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3330)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 237, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 738)
[M::mem_pestat] mean and std.dev: (266.25, 136.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 931)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (321, 708, 2573)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7077)
[M::mem_pestat] mean and std.dev: (1505.55, 1582.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9329)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 533, 1223)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3285)
[M::mem_pestat] mean and std.dev: (613.78, 607.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4316)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699474 reads in 184.836 CPU sec, 6.087 real sec
[M::mem_process_seqs] Processed 699492 reads in 125.607 CPU sec, 3.959 real sec
[M::process] read 698614 sequences (100000122 bp) in 2.747 CPU sec, 2.835 real sec...
sorting block 50, #reads = 1078147 mem = 536880661 peak = 853118976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 285007, 28, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 230, 1291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3433)
[M::mem_pestat] mean and std.dev: (479.77, 489.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4504)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 239, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 745)
[M::mem_pestat] mean and std.dev: (268.74, 138.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 940)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 513, 1806)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4994)
[M::mem_pestat] mean and std.dev: (833.63, 811.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6588)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 433, 1303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3533)
[M::mem_pestat] mean and std.dev: (436.03, 392.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4648)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697852 sequences (100000209 bp) in 3.456 CPU sec, 3.702 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 284628, 23, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 559, 1557)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4275)
[M::mem_pestat] mean and std.dev: (718.00, 765.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5634)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 242, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (270.77, 139.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 952)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 472, 854)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2128)
[M::mem_pestat] mean and std.dev: (508.68, 367.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2765)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (284, 490, 829)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1919)
[M::mem_pestat] mean and std.dev: (482.17, 303.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2464)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698764 reads in 184.073 CPU sec, 5.864 real sec
[M::mem_process_seqs] Processed 698614 reads in 125.293 CPU sec, 3.956 real sec
[M::process] read 698036 sequences (100000136 bp) in 2.537 CPU sec, 2.671 real sec...
sorting block 51, #reads = 1078432 mem = 536879736 peak = 853118976
[M::process] read 697592 sequences (100000207 bp) in 3.113 CPU sec, 3.332 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 284464, 29, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (302, 421, 1609)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4223)
[M::mem_pestat] mean and std.dev: (838.22, 799.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5530)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 243, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (272.84, 141.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 965)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 722, 1249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3375)
[M::mem_pestat] mean and std.dev: (734.93, 665.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4438)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 314, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 746)
[M::mem_pestat] mean and std.dev: (272.12, 112.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 942)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698036 reads in 107.347 CPU sec, 3.384 real sec
sorting block 52, #reads = 1078845 mem = 536878064 peak = 853118976
[M::process] read 697000 sequences (100000034 bp) in 3.153 CPU sec, 3.349 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 284868, 25, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 367, 998)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2566)
[M::mem_pestat] mean and std.dev: (525.50, 477.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3350)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 243, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 759)
[M::mem_pestat] mean and std.dev: (273.27, 141.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 958)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (507, 962, 3113)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8325)
[M::mem_pestat] mean and std.dev: (2152.48, 2450.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11956)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (275, 382, 1935)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5255)
[M::mem_pestat] mean and std.dev: (883.89, 1264.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6915)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 283575, 33, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 326, 536)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1186)
[M::mem_pestat] mean and std.dev: (368.22, 187.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1511)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 244, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (274.06, 141.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 966)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (802, 1307, 3178)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7930)
[M::mem_pestat] mean and std.dev: (1770.67, 1060.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10306)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 329, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 946)
[M::mem_pestat] mean and std.dev: (301.74, 130.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1183)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697852 reads in 290.264 CPU sec, 9.234 real sec
[M::mem_process_seqs] Processed 697592 reads in 150.379 CPU sec, 4.762 real sec
sorting block 53, #reads = 1079641 mem = 536879914 peak = 853118976
[M::process] read 697146 sequences (100000187 bp) in 2.736 CPU sec, 2.923 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 283785, 25, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 555, 2077)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5763)
[M::mem_pestat] mean and std.dev: (1243.86, 1315.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7606)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 246, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 772)
[M::mem_pestat] mean and std.dev: (276.05, 142.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 975)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (87, 246, 1637)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4737)
[M::mem_pestat] mean and std.dev: (733.70, 857.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6287)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (304, 385, 1099)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2689)
[M::mem_pestat] mean and std.dev: (701.07, 549.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3484)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696096 sequences (100000242 bp) in 3.183 CPU sec, 3.439 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 284291, 27, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 299, 477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1069)
[M::mem_pestat] mean and std.dev: (333.54, 200.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1365)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 245, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (274.27, 140.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 963)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (413, 642, 2276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6002)
[M::mem_pestat] mean and std.dev: (629.33, 599.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7865)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 385, 764)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1850)
[M::mem_pestat] mean and std.dev: (507.18, 342.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2393)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697000 reads in 187.590 CPU sec, 5.979 real sec
sorting block 54, #reads = 1076714 mem = 536877469 peak = 853118976
[M::mem_process_seqs] Processed 697146 reads in 126.748 CPU sec, 4.001 real sec
[M::process] read 695952 sequences (100000286 bp) in 2.950 CPU sec, 3.194 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 283479, 30, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 268, 1278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3362)
[M::mem_pestat] mean and std.dev: (669.35, 909.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4404)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 248, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 767)
[M::mem_pestat] mean and std.dev: (276.06, 140.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 968)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (629, 916, 1595)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3527)
[M::mem_pestat] mean and std.dev: (955.79, 576.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4493)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (318, 824, 2565)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7059)
[M::mem_pestat] mean and std.dev: (1150.69, 995.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9306)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 55, #reads = 1077205 mem = 536877998 peak = 853118976
[M::process] read 695260 sequences (100000232 bp) in 3.069 CPU sec, 3.276 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283148, 21, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 422, 944)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2356)
[M::mem_pestat] mean and std.dev: (562.69, 485.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3062)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 250, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 774)
[M::mem_pestat] mean and std.dev: (278.03, 141.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 977)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (472, 656, 2385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6211)
[M::mem_pestat] mean and std.dev: (1200.10, 1065.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8124)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 585, 932)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2364)
[M::mem_pestat] mean and std.dev: (715.37, 610.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3158)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696096 reads in 189.658 CPU sec, 6.052 real sec
[M::process] read 695132 sequences (100000046 bp) in 2.989 CPU sec, 3.190 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 282772, 42, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (282, 364, 505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 951)
[M::mem_pestat] mean and std.dev: (352.65, 150.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1174)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 252, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 775)
[M::mem_pestat] mean and std.dev: (278.82, 141.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 978)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 464, 1489)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4169)
[M::mem_pestat] mean and std.dev: (659.22, 771.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5509)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 292, 702)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1816)
[M::mem_pestat] mean and std.dev: (328.18, 228.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2373)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695260 reads in 106.659 CPU sec, 3.369 real sec
[M::process] read 695078 sequences (100000291 bp) in 2.297 CPU sec, 2.336 real sec...
sorting block 56, #reads = 1075547 mem = 536881396 peak = 853118976
[M::mem_process_seqs] Processed 695952 reads in 289.299 CPU sec, 9.163 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283354, 21, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 317, 896)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2372)
[M::mem_pestat] mean and std.dev: (512.32, 465.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3110)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 253, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 776)
[M::mem_pestat] mean and std.dev: (279.54, 141.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 979)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (339, 769, 1522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3888)
[M::mem_pestat] mean and std.dev: (966.40, 836.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5071)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (394, 435, 595)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 997)
[M::mem_pestat] mean and std.dev: (375.50, 146.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1198)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 57, #reads = 1074543 mem = 536882858 peak = 853118976
[M::process] read 695260 sequences (100000263 bp) in 3.307 CPU sec, 3.557 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 283118, 30, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 472, 801)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2033)
[M::mem_pestat] mean and std.dev: (448.19, 348.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2649)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 252, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (279.12, 141.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 975)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (325, 901, 2245)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6085)
[M::mem_pestat] mean and std.dev: (1522.67, 1567.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8005)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 383, 1016)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2586)
[M::mem_pestat] mean and std.dev: (444.46, 338.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3371)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695132 reads in 212.397 CPU sec, 6.730 real sec
[M::mem_process_seqs] Processed 695078 reads in 130.007 CPU sec, 4.103 real sec
[M::process] read 694942 sequences (100000215 bp) in 3.108 CPU sec, 3.349 real sec...
sorting block 58, #reads = 1075028 mem = 536884842 peak = 853118976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 282923, 29, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 343, 1456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3940)
[M::mem_pestat] mean and std.dev: (749.90, 716.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5182)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 252, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (278.88, 140.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 975)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (108, 170, 552)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1440)
[M::mem_pestat] mean and std.dev: (290.46, 321.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1884)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 348, 660)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1608)
[M::mem_pestat] mean and std.dev: (412.59, 301.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2082)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694682 sequences (100000201 bp) in 2.679 CPU sec, 2.870 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 282931, 26, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 424, 1068)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2862)
[M::mem_pestat] mean and std.dev: (617.15, 513.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3759)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 251, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (277.05, 138.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 959)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (266, 975, 1637)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4379)
[M::mem_pestat] mean and std.dev: (1096.92, 942.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5750)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (272, 482, 951)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2309)
[M::mem_pestat] mean and std.dev: (604.21, 444.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2988)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695260 reads in 187.296 CPU sec, 5.976 real sec
[M::mem_process_seqs] Processed 694942 reads in 128.820 CPU sec, 4.070 real sec
[M::process] read 695012 sequences (100000299 bp) in 2.483 CPU sec, 2.601 real sec...
sorting block 59, #reads = 1074183 mem = 536891010 peak = 853118976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 282504, 30, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 318, 1096)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2828)
[M::mem_pestat] mean and std.dev: (603.07, 663.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3694)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 252, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 767)
[M::mem_pestat] mean and std.dev: (277.74, 139.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 967)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (589, 1536, 3211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8455)
[M::mem_pestat] mean and std.dev: (2089.07, 2082.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11077)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 342, 768)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1944)
[M::mem_pestat] mean and std.dev: (403.97, 281.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2532)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698874 sequences (100000037 bp) in 3.046 CPU sec, 3.277 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 282685, 27, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 358, 1234)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3362)
[M::mem_pestat] mean and std.dev: (612.30, 654.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4426)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 251, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (277.08, 138.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 963)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (472, 749, 1689)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4123)
[M::mem_pestat] mean and std.dev: (966.54, 713.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5340)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 312, 970)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2564)
[M::mem_pestat] mean and std.dev: (623.23, 620.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3361)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694682 reads in 189.400 CPU sec, 6.056 real sec
[M::mem_process_seqs] Processed 695012 reads in 131.929 CPU sec, 4.167 real sec
sorting block 60, #reads = 1073198 mem = 536879052 peak = 853118976
[M::process] read 704270 sequences (100000170 bp) in 3.174 CPU sec, 3.390 real sec...
sorting block 61, #reads = 1072668 mem = 536880291 peak = 853118976
[M::process] read 703904 sequences (100000135 bp) in 3.040 CPU sec, 3.206 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 286359, 29, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 583, 1157)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3077)
[M::mem_pestat] mean and std.dev: (516.10, 403.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4037)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 220, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 673)
[M::mem_pestat] mean and std.dev: (248.98, 127.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 847)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (92, 817, 1722)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4982)
[M::mem_pestat] mean and std.dev: (1016.75, 1078.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6612)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 486, 1228)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3176)
[M::mem_pestat] mean and std.dev: (697.06, 593.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4150)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704270 reads in 116.230 CPU sec, 3.650 real sec
[M::process] read 703284 sequences (100000136 bp) in 2.106 CPU sec, 2.127 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 284127, 23, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 337, 519)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1241)
[M::mem_pestat] mean and std.dev: (355.92, 285.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1602)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 238, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 736)
[M::mem_pestat] mean and std.dev: (266.54, 135.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 928)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (100, 499, 878)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2434)
[M::mem_pestat] mean and std.dev: (508.09, 409.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3212)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 319, 1434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3878)
[M::mem_pestat] mean and std.dev: (700.16, 864.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5100)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 286539, 19, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 420, 764)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1966)
[M::mem_pestat] mean and std.dev: (500.70, 408.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2567)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 222, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (252.59, 130.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (766, 1332, 1592)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3244)
[M::mem_pestat] mean and std.dev: (1274.53, 757.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4305)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 346, 544)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1156)
[M::mem_pestat] mean and std.dev: (364.96, 212.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1462)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698874 reads in 319.201 CPU sec, 10.150 real sec
[M::process] read 700864 sequences (100000110 bp) in 2.558 CPU sec, 2.624 real sec...
[M::mem_process_seqs] Processed 703904 reads in 161.716 CPU sec, 5.140 real sec
sorting block 62, #reads = 1075267 mem = 536880427 peak = 853118976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 286565, 25, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 250, 401)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 907)
[M::mem_pestat] mean and std.dev: (241.65, 125.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1160)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 224, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (253.96, 131.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 873)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (298, 958, 8582)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 25150)
[M::mem_pestat] mean and std.dev: (3053.72, 3514.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 33434)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 461, 827)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1973)
[M::mem_pestat] mean and std.dev: (473.48, 397.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2546)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 63, #reads = 1074199 mem = 536880026 peak = 853118976
[M::process] read 699918 sequences (100000010 bp) in 3.163 CPU sec, 3.408 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 285864, 25, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 334, 821)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2135)
[M::mem_pestat] mean and std.dev: (465.00, 529.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2792)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 232, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 726)
[M::mem_pestat] mean and std.dev: (262.21, 135.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 916)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (365, 449, 3237)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8981)
[M::mem_pestat] mean and std.dev: (1285.80, 1443.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11853)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 322, 557)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1213)
[M::mem_pestat] mean and std.dev: (355.00, 214.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1541)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703284 reads in 197.080 CPU sec, 6.465 real sec
[M::process] read 699352 sequences (100000283 bp) in 2.194 CPU sec, 2.210 real sec...
[M::mem_process_seqs] Processed 700864 reads in 127.286 CPU sec, 4.032 real sec
sorting block 64, #reads = 1076132 mem = 536878572 peak = 853118976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 285021, 27, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (261, 536, 1310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3408)
[M::mem_pestat] mean and std.dev: (724.93, 626.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4457)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 233, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 733)
[M::mem_pestat] mean and std.dev: (264.75, 137.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 925)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 680, 3719)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10781)
[M::mem_pestat] mean and std.dev: (1648.89, 1815.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14312)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 405, 907)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2385)
[M::mem_pestat] mean and std.dev: (433.62, 384.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3124)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698876 sequences (100000079 bp) in 3.541 CPU sec, 3.825 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 285115, 15, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 373, 510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1142)
[M::mem_pestat] mean and std.dev: (397.62, 240.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1458)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 237, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 747)
[M::mem_pestat] mean and std.dev: (267.90, 139.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 943)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 428, 1620)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4432)
[M::mem_pestat] mean and std.dev: (637.75, 624.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5838)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (283, 372, 762)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1720)
[M::mem_pestat] mean and std.dev: (398.13, 236.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2199)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699918 reads in 191.688 CPU sec, 6.101 real sec
[M::mem_process_seqs] Processed 699352 reads in 127.433 CPU sec, 4.028 real sec
[M::process] read 698692 sequences (100000098 bp) in 3.021 CPU sec, 3.147 real sec...
sorting block 65, #reads = 1077170 mem = 536879002 peak = 853118976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 285763, 17, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 487, 1195)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3167)
[M::mem_pestat] mean and std.dev: (648.23, 482.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4153)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 239, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (270.18, 140.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 955)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (103, 1609, 1992)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5770)
[M::mem_pestat] mean and std.dev: (1244.65, 1125.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7659)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 490, 1701)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4657)
[M::mem_pestat] mean and std.dev: (828.00, 919.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6135)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697974 sequences (100000215 bp) in 3.305 CPU sec, 3.521 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 284712, 36, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 266, 487)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1091)
[M::mem_pestat] mean and std.dev: (326.14, 221.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1393)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 239, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (270.92, 140.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 956)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (113, 242, 1223)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3443)
[M::mem_pestat] mean and std.dev: (500.69, 471.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4553)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (259, 351, 460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 862)
[M::mem_pestat] mean and std.dev: (334.05, 131.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1063)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698876 reads in 192.538 CPU sec, 6.134 real sec
[M::mem_process_seqs] Processed 698692 reads in 131.542 CPU sec, 4.146 real sec
sorting block 66, #reads = 1076891 mem = 536881897 peak = 853118976
[M::process] read 698010 sequences (100000088 bp) in 2.784 CPU sec, 2.931 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 284851, 9, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 270, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1054)
[M::mem_pestat] mean and std.dev: (306.32, 200.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1346)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 241, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (273.17, 142.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 965)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 536, 911)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2299)
[M::mem_pestat] mean and std.dev: (617.69, 514.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2993)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 698022 sequences (100000273 bp) in 2.999 CPU sec, 3.231 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 284809, 21, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 348, 1236)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3298)
[M::mem_pestat] mean and std.dev: (549.68, 578.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4329)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 242, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (274.36, 143.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 977)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (388, 1135, 5303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 15133)
[M::mem_pestat] mean and std.dev: (2186.48, 2204.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 20048)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 431, 1447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3877)
[M::mem_pestat] mean and std.dev: (865.21, 942.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5092)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697974 reads in 194.870 CPU sec, 6.211 real sec
sorting block 67, #reads = 1075842 mem = 536881662 peak = 853118976
[M::mem_process_seqs] Processed 698010 reads in 131.937 CPU sec, 4.154 real sec
[M::process] read 697222 sequences (100000035 bp) in 2.489 CPU sec, 2.584 real sec...
sorting block 68, #reads = 1074650 mem = 536878933 peak = 861687808
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 284091, 18, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 392, 1459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4003)
[M::mem_pestat] mean and std.dev: (587.03, 519.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5275)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 241, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (272.67, 142.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 961)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (405, 735, 1148)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2634)
[M::mem_pestat] mean and std.dev: (831.67, 587.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3377)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 381, 779)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2025)
[M::mem_pestat] mean and std.dev: (375.24, 254.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2648)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696634 sequences (100000220 bp) in 3.219 CPU sec, 3.426 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 284549, 25, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 331, 856)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2156)
[M::mem_pestat] mean and std.dev: (515.22, 491.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2806)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 244, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 762)
[M::mem_pestat] mean and std.dev: (273.79, 141.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 962)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (318, 503, 1691)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4437)
[M::mem_pestat] mean and std.dev: (999.17, 1105.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5810)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 228, 534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1224)
[M::mem_pestat] mean and std.dev: (295.40, 194.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1569)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695902 sequences (100000194 bp) in 2.150 CPU sec, 2.147 real sec...
[M::mem_process_seqs] Processed 698022 reads in 202.059 CPU sec, 6.416 real sec
[M::mem_process_seqs] Processed 697222 reads in 139.779 CPU sec, 4.424 real sec
sorting block 69, #reads = 1073751 mem = 536880238 peak = 861687808
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 283305, 24, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 276, 752)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1952)
[M::mem_pestat] mean and std.dev: (484.72, 462.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2552)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 245, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (274.96, 141.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 963)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (31, 327, 1200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3538)
[M::mem_pestat] mean and std.dev: (499.17, 513.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4707)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 451, 658)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1576)
[M::mem_pestat] mean and std.dev: (414.97, 274.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2035)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696036 sequences (100000212 bp) in 3.248 CPU sec, 3.471 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 283431, 31, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 408, 651)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1463)
[M::mem_pestat] mean and std.dev: (403.54, 235.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1869)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (276.63, 142.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 965)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (530, 755, 2048)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5084)
[M::mem_pestat] mean and std.dev: (1137.70, 1147.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6602)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 375, 1224)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3268)
[M::mem_pestat] mean and std.dev: (625.57, 606.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4290)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696280 sequences (100000017 bp) in 2.289 CPU sec, 2.295 real sec...
[M::mem_process_seqs] Processed 696634 reads in 205.917 CPU sec, 6.642 real sec
[M::mem_process_seqs] Processed 695902 reads in 137.560 CPU sec, 4.351 real sec
sorting block 70, #reads = 1072246 mem = 536878462 peak = 861687808
[M::process] read 696684 sequences (100000233 bp) in 2.973 CPU sec, 3.165 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 283275, 18, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 216, 959)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2489)
[M::mem_pestat] mean and std.dev: (474.48, 524.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3254)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 244, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (273.85, 140.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 956)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (401, 597, 1611)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4031)
[M::mem_pestat] mean and std.dev: (837.76, 827.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5241)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 539, 1033)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2675)
[M::mem_pestat] mean and std.dev: (674.50, 622.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3496)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697180 sequences (100000085 bp) in 2.300 CPU sec, 2.304 real sec...
[M::mem_process_seqs] Processed 696280 reads in 119.470 CPU sec, 3.778 real sec
sorting block 71, #reads = 1071460 mem = 536880911 peak = 861687808
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 282729, 31, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 368, 1083)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2901)
[M::mem_pestat] mean and std.dev: (513.35, 545.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3810)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 246, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (275.47, 141.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 964)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (505, 689, 1442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3316)
[M::mem_pestat] mean and std.dev: (890.85, 794.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4253)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 326, 938)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2450)
[M::mem_pestat] mean and std.dev: (547.84, 513.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3206)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283145, 12, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 283, 1049)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2777)
[M::mem_pestat] mean and std.dev: (609.21, 704.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3641)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 243, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (272.61, 139.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 947)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (410, 691, 1100)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2480)
[M::mem_pestat] mean and std.dev: (667.42, 363.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3170)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 376, 1266)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3390)
[M::mem_pestat] mean and std.dev: (437.40, 365.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4452)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696036 reads in 316.309 CPU sec, 10.107 real sec
[M::process] read 696494 sequences (100000274 bp) in 2.418 CPU sec, 2.441 real sec...
[M::mem_process_seqs] Processed 696684 reads in 164.368 CPU sec, 5.228 real sec
sorting block 72, #reads = 1070727 mem = 536878363 peak = 861687808
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 283523, 30, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (364, 590, 1937)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5083)
[M::mem_pestat] mean and std.dev: (848.90, 937.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6656)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 242, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 747)
[M::mem_pestat] mean and std.dev: (271.52, 139.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 942)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 842, 1384)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3754)
[M::mem_pestat] mean and std.dev: (903.79, 836.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4939)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 405, 1954)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5388)
[M::mem_pestat] mean and std.dev: (1010.27, 1153.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7105)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696504 sequences (100000227 bp) in 3.314 CPU sec, 3.575 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 283723, 26, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 291, 1264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3320)
[M::mem_pestat] mean and std.dev: (651.47, 655.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4348)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 243, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (272.55, 139.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 947)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 845, 1617)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4393)
[M::mem_pestat] mean and std.dev: (1099.00, 979.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5781)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 357, 1037)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2603)
[M::mem_pestat] mean and std.dev: (659.27, 663.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3386)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696630 sequences (100000188 bp) in 2.180 CPU sec, 2.179 real sec...
[M::mem_process_seqs] Processed 697180 reads in 206.350 CPU sec, 6.822 real sec
sorting block 73, #reads = 1071341 mem = 536879712 peak = 861687808
[M::mem_process_seqs] Processed 696494 reads in 134.684 CPU sec, 4.384 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 282939, 26, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 312, 712)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1802)
[M::mem_pestat] mean and std.dev: (311.54, 222.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2347)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (272.74, 139.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 947)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 323, 1036)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2734)
[M::mem_pestat] mean and std.dev: (457.78, 445.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3583)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 397, 724)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1844)
[M::mem_pestat] mean and std.dev: (422.24, 322.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2404)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 74, #reads = 1070907 mem = 536880810 peak = 861687808
[M::process] read 700060 sequences (100000270 bp) in 3.236 CPU sec, 3.501 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 282913, 21, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 283, 667)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1621)
[M::mem_pestat] mean and std.dev: (372.23, 302.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2098)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (272.94, 139.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 951)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (305, 940, 2611)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7223)
[M::mem_pestat] mean and std.dev: (1724.24, 2092.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10096)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (266, 547, 1743)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4697)
[M::mem_pestat] mean and std.dev: (930.12, 814.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6174)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707068 sequences (100000226 bp) in 2.300 CPU sec, 2.296 real sec...
[M::mem_process_seqs] Processed 696504 reads in 203.787 CPU sec, 6.583 real sec
[M::mem_process_seqs] Processed 696630 reads in 134.345 CPU sec, 4.243 real sec
sorting block 75, #reads = 1070109 mem = 536877877 peak = 861687808
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 284476, 29, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 407, 1044)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2820)
[M::mem_pestat] mean and std.dev: (530.49, 510.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3708)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 233, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 724)
[M::mem_pestat] mean and std.dev: (262.89, 135.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 913)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (303, 834, 2482)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6840)
[M::mem_pestat] mean and std.dev: (1209.48, 1124.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9019)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 538, 925)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2285)
[M::mem_pestat] mean and std.dev: (598.22, 461.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2965)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705770 sequences (100000149 bp) in 3.179 CPU sec, 3.353 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 287040, 27, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 565, 1132)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3036)
[M::mem_pestat] mean and std.dev: (509.18, 450.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3988)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 214, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 649)
[M::mem_pestat] mean and std.dev: (241.78, 122.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 816)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (407, 727, 1179)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2723)
[M::mem_pestat] mean and std.dev: (738.68, 556.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3495)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 391, 942)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2430)
[M::mem_pestat] mean and std.dev: (515.43, 446.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3174)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705446 sequences (100000073 bp) in 2.279 CPU sec, 2.279 real sec...
[M::mem_process_seqs] Processed 700060 reads in 220.858 CPU sec, 7.117 real sec
[M::mem_process_seqs] Processed 707068 reads in 144.956 CPU sec, 4.589 real sec
sorting block 76, #reads = 1068682 mem = 536881960 peak = 861687808
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 287246, 24, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 270, 777)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1967)
[M::mem_pestat] mean and std.dev: (511.57, 520.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2593)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 219, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 672)
[M::mem_pestat] mean and std.dev: (247.48, 126.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 846)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (346, 609, 1091)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2581)
[M::mem_pestat] mean and std.dev: (650.95, 571.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3326)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 451, 2654)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7534)
[M::mem_pestat] mean and std.dev: (1211.06, 1592.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9974)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703802 sequences (100000172 bp) in 3.086 CPU sec, 3.311 real sec...
[M::process] read 703060 sequences (100000070 bp) in 2.230 CPU sec, 2.233 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 286770, 24, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 378, 1038)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2688)
[M::mem_pestat] mean and std.dev: (585.53, 491.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3513)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 218, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 669)
[M::mem_pestat] mean and std.dev: (246.90, 125.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 842)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (307, 719, 2575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7111)
[M::mem_pestat] mean and std.dev: (1096.26, 1118.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9379)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 241, 606)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1510)
[M::mem_pestat] mean and std.dev: (344.56, 274.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1962)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705770 reads in 224.161 CPU sec, 7.141 real sec
sorting block 77, #reads = 1069625 mem = 536878897 peak = 861687808
[M::mem_process_seqs] Processed 705446 reads in 153.750 CPU sec, 5.261 real sec
sorting block 78, #reads = 1071358 mem = 536878309 peak = 861687808
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 286834, 17, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (123, 230, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1170)
[M::mem_pestat] mean and std.dev: (263.41, 184.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1519)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (252.21, 128.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 813, 2973)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8477)
[M::mem_pestat] mean and std.dev: (1467.88, 1489.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11229)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 339, 1089)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2817)
[M::mem_pestat] mean and std.dev: (639.55, 574.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3681)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701738 sequences (100000078 bp) in 3.262 CPU sec, 3.481 real sec...
[M::process] read 700620 sequences (100000179 bp) in 2.430 CPU sec, 2.437 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 285812, 19, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 351, 601)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1315)
[M::mem_pestat] mean and std.dev: (353.32, 224.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1672)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 225, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (254.61, 130.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 877)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (320, 853, 2291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6233)
[M::mem_pestat] mean and std.dev: (1128.12, 1072.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8204)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 283, 692)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1608)
[M::mem_pestat] mean and std.dev: (477.97, 359.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2066)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703802 reads in 226.749 CPU sec, 7.576 real sec
[M::mem_process_seqs] Processed 703060 reads in 152.602 CPU sec, 4.858 real sec
sorting block 79, #reads = 1070489 mem = 536880314 peak = 861687808
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 285974, 18, 19)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 403, 1308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3462)
[M::mem_pestat] mean and std.dev: (816.80, 785.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4539)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 229, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 713)
[M::mem_pestat] mean and std.dev: (258.73, 132.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 899)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (705, 1747, 3833)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10089)
[M::mem_pestat] mean and std.dev: (2226.61, 1813.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13217)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (391, 634, 1128)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2602)
[M::mem_pestat] mean and std.dev: (851.61, 668.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3527)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699818 sequences (100000025 bp) in 3.448 CPU sec, 3.718 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 285589, 23, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 439, 2122)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5962)
[M::mem_pestat] mean and std.dev: (785.63, 784.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7882)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 232, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 723)
[M::mem_pestat] mean and std.dev: (261.55, 133.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 912)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 447, 1473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4093)
[M::mem_pestat] mean and std.dev: (822.09, 693.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5403)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 248, 586)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1378)
[M::mem_pestat] mean and std.dev: (392.44, 279.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1774)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701738 reads in 211.403 CPU sec, 6.716 real sec
[M::process] read 699448 sequences (100000261 bp) in 2.434 CPU sec, 2.441 real sec...
[M::mem_process_seqs] Processed 700620 reads in 142.784 CPU sec, 4.625 real sec
sorting block 80, #reads = 1071310 mem = 536877316 peak = 861687808
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 285136, 30, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 485, 2035)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5629)
[M::mem_pestat] mean and std.dev: (1288.08, 1551.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7496)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 731)
[M::mem_pestat] mean and std.dev: (264.53, 135.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 922)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (336, 751, 4037)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11439)
[M::mem_pestat] mean and std.dev: (2125.00, 2648.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 15140)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 294, 669)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1571)
[M::mem_pestat] mean and std.dev: (282.33, 122.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2022)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699084 sequences (100000182 bp) in 3.503 CPU sec, 3.770 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 285702, 24, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (277, 478, 891)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2119)
[M::mem_pestat] mean and std.dev: (532.75, 411.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2733)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 236, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 737)
[M::mem_pestat] mean and std.dev: (265.71, 136.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 930)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (302, 809, 1141)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2819)
[M::mem_pestat] mean and std.dev: (713.75, 503.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3658)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 287, 500)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1212)
[M::mem_pestat] mean and std.dev: (337.90, 265.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1568)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699818 reads in 211.164 CPU sec, 6.815 real sec
[M::process] read 699224 sequences (100000185 bp) in 2.422 CPU sec, 2.426 real sec...
sorting block 81, #reads = 1072478 mem = 536880125 peak = 861687808
[M::mem_process_seqs] Processed 699448 reads in 143.782 CPU sec, 4.584 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 285113, 30, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 330, 687)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1651)
[M::mem_pestat] mean and std.dev: (437.11, 330.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2133)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 236, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 738)
[M::mem_pestat] mean and std.dev: (266.54, 137.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 931)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 469, 1000)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2670)
[M::mem_pestat] mean and std.dev: (587.11, 579.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3505)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 320, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (3, 588)
[M::mem_pestat] mean and std.dev: (274.56, 85.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 705)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 82, #reads = 1073765 mem = 536878933 peak = 861687808
[M::process] read 697962 sequences (100000104 bp) in 3.156 CPU sec, 3.402 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 285024, 32, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (253, 362, 1398)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3688)
[M::mem_pestat] mean and std.dev: (701.21, 719.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4833)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 236, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 744)
[M::mem_pestat] mean and std.dev: (268.02, 139.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 939)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (119, 708, 1785)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5117)
[M::mem_pestat] mean and std.dev: (819.07, 815.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6783)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (445, 579, 1086)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2368)
[M::mem_pestat] mean and std.dev: (773.40, 616.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3241)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697942 sequences (100000270 bp) in 2.390 CPU sec, 2.403 real sec...
[M::mem_process_seqs] Processed 699084 reads in 210.321 CPU sec, 6.733 real sec
[M::mem_process_seqs] Processed 699224 reads in 140.145 CPU sec, 4.546 real sec
sorting block 83, #reads = 1074213 mem = 536879998 peak = 861687808
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 283720, 22, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 300, 869)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2247)
[M::mem_pestat] mean and std.dev: (375.71, 278.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2936)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 239, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 742)
[M::mem_pestat] mean and std.dev: (268.30, 136.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 936)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (132, 580, 1527)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4317)
[M::mem_pestat] mean and std.dev: (767.20, 882.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5712)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 309, 725)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1735)
[M::mem_pestat] mean and std.dev: (367.55, 270.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2240)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696920 sequences (100000156 bp) in 3.200 CPU sec, 3.404 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 283614, 37, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 337, 1096)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2874)
[M::mem_pestat] mean and std.dev: (556.16, 565.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3763)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 240, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 752)
[M::mem_pestat] mean and std.dev: (270.84, 139.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 747, 1619)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4445)
[M::mem_pestat] mean and std.dev: (1060.84, 1049.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5858)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (337, 563, 2336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6334)
[M::mem_pestat] mean and std.dev: (1045.95, 1062.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8333)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696604 sequences (100000156 bp) in 2.154 CPU sec, 2.162 real sec...
[M::mem_process_seqs] Processed 697962 reads in 214.476 CPU sec, 6.930 real sec
[M::mem_process_seqs] Processed 697942 reads in 142.549 CPU sec, 4.514 real sec
sorting block 84, #reads = 1072173 mem = 536883182 peak = 861687808
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 283598, 29, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 296, 1082)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2948)
[M::mem_pestat] mean and std.dev: (567.33, 684.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3881)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 242, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 759)
[M::mem_pestat] mean and std.dev: (273.39, 141.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 958)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (91, 614, 924)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2590)
[M::mem_pestat] mean and std.dev: (558.56, 507.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3423)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 320, 905)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2225)
[M::mem_pestat] mean and std.dev: (388.42, 274.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2885)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696910 sequences (100000039 bp) in 3.262 CPU sec, 3.470 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 283407, 19, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 347, 1467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3973)
[M::mem_pestat] mean and std.dev: (808.44, 972.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5226)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 243, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (273.55, 141.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 955)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (129, 140, 1049)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2889)
[M::mem_pestat] mean and std.dev: (509.33, 546.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3809)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 305, 532)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1150)
[M::mem_pestat] mean and std.dev: (316.14, 167.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1459)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697056 sequences (100000289 bp) in 2.222 CPU sec, 2.231 real sec...
[M::mem_process_seqs] Processed 696920 reads in 210.303 CPU sec, 6.711 real sec
sorting block 85, #reads = 1071141 mem = 536880761 peak = 861687808
[M::mem_process_seqs] Processed 696604 reads in 138.755 CPU sec, 4.387 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 283557, 17, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (315, 654, 1658)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4344)
[M::mem_pestat] mean and std.dev: (949.68, 789.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5687)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 243, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (273.98, 141.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 959)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (359, 930, 3584)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10034)
[M::mem_pestat] mean and std.dev: (1554.53, 1512.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13259)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (269, 450, 1739)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4679)
[M::mem_pestat] mean and std.dev: (851.93, 764.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6149)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 86, #reads = 1070925 mem = 536877992 peak = 861687808
[M::process] read 696934 sequences (100000290 bp) in 3.309 CPU sec, 3.525 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 283832, 18, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 503, 1133)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2971)
[M::mem_pestat] mean and std.dev: (527.59, 404.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3890)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 243, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 759)
[M::mem_pestat] mean and std.dev: (273.66, 141.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 958)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (301, 1192, 2146)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5836)
[M::mem_pestat] mean and std.dev: (1710.83, 1785.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8855)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 305, 1064)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2836)
[M::mem_pestat] mean and std.dev: (491.00, 465.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3722)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696954 sequences (100000277 bp) in 2.364 CPU sec, 2.365 real sec...
[M::mem_process_seqs] Processed 696910 reads in 206.662 CPU sec, 6.687 real sec
[M::mem_process_seqs] Processed 697056 reads in 141.175 CPU sec, 4.473 real sec
sorting block 87, #reads = 1072051 mem = 536879742 peak = 861687808
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 283498, 28, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 498, 1426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3878)
[M::mem_pestat] mean and std.dev: (748.27, 688.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5104)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 243, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 759)
[M::mem_pestat] mean and std.dev: (273.71, 141.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 958)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 760, 2763)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7855)
[M::mem_pestat] mean and std.dev: (940.78, 1026.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10401)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (365, 457, 1015)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2315)
[M::mem_pestat] mean and std.dev: (589.79, 382.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2965)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696920 sequences (100000165 bp) in 2.921 CPU sec, 3.125 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 283901, 23, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 442, 717)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1667)
[M::mem_pestat] mean and std.dev: (491.30, 334.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2142)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 242, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 762)
[M::mem_pestat] mean and std.dev: (273.94, 142.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 962)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (523, 828, 1782)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4300)
[M::mem_pestat] mean and std.dev: (1219.74, 998.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5559)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 351, 1021)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2625)
[M::mem_pestat] mean and std.dev: (602.42, 521.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3427)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702628 sequences (100000206 bp) in 1.950 CPU sec, 1.949 real sec...
[M::mem_process_seqs] Processed 696934 reads in 208.019 CPU sec, 6.645 real sec
[M::mem_process_seqs] Processed 696954 reads in 140.874 CPU sec, 4.728 real sec
sorting block 88, #reads = 1071313 mem = 536878938 peak = 861687808
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 283217, 21, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 309, 528)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1178)
[M::mem_pestat] mean and std.dev: (361.25, 254.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1503)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 243, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (274.80, 143.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 966)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 947, 2696)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7594)
[M::mem_pestat] mean and std.dev: (1415.57, 1181.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10043)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 285, 610)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1472)
[M::mem_pestat] mean and std.dev: (384.27, 285.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1903)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704168 sequences (100000030 bp) in 3.217 CPU sec, 3.411 real sec...
[M::process] read 703984 sequences (100000151 bp) in 2.236 CPU sec, 2.241 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 284988, 28, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 269, 690)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1732)
[M::mem_pestat] mean and std.dev: (358.67, 297.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2253)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 226, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697)
[M::mem_pestat] mean and std.dev: (255.15, 131.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 878)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (499, 858, 1278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2836)
[M::mem_pestat] mean and std.dev: (820.81, 615.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3615)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 377, 744)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1788)
[M::mem_pestat] mean and std.dev: (450.21, 301.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2310)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696920 reads in 226.512 CPU sec, 7.461 real sec
sorting block 89, #reads = 1070024 mem = 536881219 peak = 861687808
[M::mem_process_seqs] Processed 702628 reads in 157.049 CPU sec, 5.090 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 286181, 28, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 473, 850)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2038)
[M::mem_pestat] mean and std.dev: (536.12, 377.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2632)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 222, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (250.81, 128.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 863)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (748, 1676, 2880)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7144)
[M::mem_pestat] mean and std.dev: (1597.00, 1136.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9276)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 485, 850)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2040)
[M::mem_pestat] mean and std.dev: (586.31, 477.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2635)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 90, #reads = 1064093 mem = 536883164 peak = 861687808
[M::process] read 702036 sequences (100000147 bp) in 3.373 CPU sec, 3.588 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 287165, 21, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 329, 1159)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3069)
[M::mem_pestat] mean and std.dev: (665.41, 744.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4024)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 222, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (251.57, 129.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 867)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (115, 523, 999)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2767)
[M::mem_pestat] mean and std.dev: (415.78, 353.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3651)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 322, 694)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1702)
[M::mem_pestat] mean and std.dev: (431.53, 411.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2206)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701224 sequences (100000254 bp) in 2.181 CPU sec, 2.193 real sec...
[M::mem_process_seqs] Processed 704168 reads in 205.608 CPU sec, 6.616 real sec
[M::mem_process_seqs] Processed 703984 reads in 135.074 CPU sec, 4.271 real sec
sorting block 91, #reads = 1077870 mem = 536887342 peak = 861687808
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 286091, 19, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 289, 538)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1284)
[M::mem_pestat] mean and std.dev: (347.77, 282.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1657)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709)
[M::mem_pestat] mean and std.dev: (257.76, 132.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 894)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (446, 551, 2359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6185)
[M::mem_pestat] mean and std.dev: (1453.89, 1746.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8441)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 415, 3122)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8864)
[M::mem_pestat] mean and std.dev: (1608.71, 1947.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11735)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700172 sequences (100000091 bp) in 3.246 CPU sec, 3.459 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 285788, 12, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 229, 417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 895)
[M::mem_pestat] mean and std.dev: (273.11, 158.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1134)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 230, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 716)
[M::mem_pestat] mean and std.dev: (259.98, 134.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 903)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (115, 468, 1399)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3967)
[M::mem_pestat] mean and std.dev: (804.08, 1002.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5251)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 418, 833)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2049)
[M::mem_pestat] mean and std.dev: (481.31, 398.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2657)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702036 reads in 198.208 CPU sec, 6.369 real sec
[M::process] read 699430 sequences (100000074 bp) in 2.404 CPU sec, 2.451 real sec...
[M::mem_process_seqs] Processed 701224 reads in 132.021 CPU sec, 4.371 real sec
sorting block 92, #reads = 1077139 mem = 536878289 peak = 861687808
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 285228, 15, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 314, 1448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3990)
[M::mem_pestat] mean and std.dev: (514.32, 482.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5261)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 234, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 727)
[M::mem_pestat] mean and std.dev: (263.51, 135.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 917)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (352, 504, 2410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6526)
[M::mem_pestat] mean and std.dev: (1049.60, 1040.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8584)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 741, 1656)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4540)
[M::mem_pestat] mean and std.dev: (1116.24, 1040.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5982)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698696 sequences (100000123 bp) in 3.615 CPU sec, 3.864 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 284608, 17, 17)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (333, 482, 992)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2310)
[M::mem_pestat] mean and std.dev: (533.85, 337.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2969)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 236, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 734)
[M::mem_pestat] mean and std.dev: (265.17, 136.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 926)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 702, 1225)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3271)
[M::mem_pestat] mean and std.dev: (827.76, 814.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4294)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 540, 1911)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5221)
[M::mem_pestat] mean and std.dev: (1199.29, 1521.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7286)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700172 reads in 189.530 CPU sec, 6.228 real sec
[M::mem_process_seqs] Processed 699430 reads in 127.044 CPU sec, 4.010 real sec
[M::process] read 699022 sequences (100000149 bp) in 2.560 CPU sec, 2.674 real sec...
sorting block 93, #reads = 1077835 mem = 536880962 peak = 861687808
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 285150, 20, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (269, 412, 1494)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3944)
[M::mem_pestat] mean and std.dev: (923.82, 1159.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5561)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 238, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 741)
[M::mem_pestat] mean and std.dev: (267.40, 137.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 935)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 700, 1406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3848)
[M::mem_pestat] mean and std.dev: (942.40, 974.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5069)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 178, 263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 535)
[M::mem_pestat] mean and std.dev: (196.83, 90.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 671)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698698 sequences (100000044 bp) in 3.163 CPU sec, 3.387 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 285329, 18, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 353, 1124)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3040)
[M::mem_pestat] mean and std.dev: (581.55, 631.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3998)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 238, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 738)
[M::mem_pestat] mean and std.dev: (267.05, 136.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 931)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (676, 1272, 4006)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10666)
[M::mem_pestat] mean and std.dev: (2365.17, 2111.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13996)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 314, 684)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1564)
[M::mem_pestat] mean and std.dev: (371.28, 194.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2004)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698696 reads in 198.170 CPU sec, 6.327 real sec
sorting block 94, #reads = 1077443 mem = 536880472 peak = 861687808
[M::mem_process_seqs] Processed 699022 reads in 135.138 CPU sec, 4.275 real sec
[M::process] read 698566 sequences (100000205 bp) in 2.587 CPU sec, 2.647 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 284934, 25, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 498, 2086)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5880)
[M::mem_pestat] mean and std.dev: (1001.88, 1209.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7777)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 238, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 738)
[M::mem_pestat] mean and std.dev: (266.88, 136.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 931)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 620, 2880)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8292)
[M::mem_pestat] mean and std.dev: (1684.56, 2412.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11334)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (372, 557, 1332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3252)
[M::mem_pestat] mean and std.dev: (785.75, 572.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4212)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 95, #reads = 1077349 mem = 536878633 peak = 861687808
[M::process] read 698598 sequences (100000058 bp) in 3.487 CPU sec, 3.758 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 284575, 14, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 237, 548)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1338)
[M::mem_pestat] mean and std.dev: (309.41, 207.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1733)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 239, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 739)
[M::mem_pestat] mean and std.dev: (267.44, 136.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 932)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (293, 792, 1602)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4220)
[M::mem_pestat] mean and std.dev: (989.07, 805.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5529)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 336, 1960)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5374)
[M::mem_pestat] mean and std.dev: (749.27, 826.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7081)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698698 reads in 199.075 CPU sec, 6.349 real sec
[M::process] read 699030 sequences (100000133 bp) in 2.325 CPU sec, 2.368 real sec...
[M::mem_process_seqs] Processed 698566 reads in 134.760 CPU sec, 4.441 real sec
sorting block 96, #reads = 1075535 mem = 536881246 peak = 861687808
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 284825, 24, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 198, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 834)
[M::mem_pestat] mean and std.dev: (231.14, 111.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1064)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 237, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 736)
[M::mem_pestat] mean and std.dev: (267.09, 137.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 928)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (383, 575, 2019)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5291)
[M::mem_pestat] mean and std.dev: (1016.91, 975.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6927)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 327, 663)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1581)
[M::mem_pestat] mean and std.dev: (466.50, 361.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2040)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699656 sequences (100000131 bp) in 3.377 CPU sec, 3.604 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 284281, 22, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 317, 1362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3700)
[M::mem_pestat] mean and std.dev: (834.04, 977.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4869)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 235, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 726)
[M::mem_pestat] mean and std.dev: (264.21, 134.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 915)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (86, 337, 780)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2168)
[M::mem_pestat] mean and std.dev: (314.44, 329.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2862)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 399, 963)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2399)
[M::mem_pestat] mean and std.dev: (666.98, 567.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3117)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698598 reads in 204.349 CPU sec, 6.682 real sec
[M::process] read 699926 sequences (100000058 bp) in 2.267 CPU sec, 2.279 real sec...
[M::mem_process_seqs] Processed 699030 reads in 136.006 CPU sec, 4.294 real sec
sorting block 97, #reads = 1074019 mem = 536880722 peak = 861687808
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 284691, 22, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 291, 2019)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5685)
[M::mem_pestat] mean and std.dev: (1288.55, 1617.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7760)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 233, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 719)
[M::mem_pestat] mean and std.dev: (262.38, 133.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 906)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (268, 793, 1976)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5392)
[M::mem_pestat] mean and std.dev: (942.24, 810.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7100)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 625, 1136)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3000)
[M::mem_pestat] mean and std.dev: (697.80, 550.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3932)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698346 sequences (100000226 bp) in 3.106 CPU sec, 3.297 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 285080, 11, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 306, 599)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1433)
[M::mem_pestat] mean and std.dev: (403.46, 367.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1875)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 232, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 718)
[M::mem_pestat] mean and std.dev: (261.65, 133.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 905)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (55, 135, 1072)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3106)
[M::mem_pestat] mean and std.dev: (636.00, 907.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4264)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 383, 864)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2176)
[M::mem_pestat] mean and std.dev: (475.35, 353.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2832)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698004 sequences (100000175 bp) in 2.120 CPU sec, 2.122 real sec...
[M::mem_process_seqs] Processed 699656 reads in 205.970 CPU sec, 6.827 real sec
sorting block 98, #reads = 1075241 mem = 536877717 peak = 861687808
[M::mem_process_seqs] Processed 699926 reads in 136.876 CPU sec, 4.342 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 284320, 30, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (268, 604, 1385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3619)
[M::mem_pestat] mean and std.dev: (711.54, 580.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4736)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 238, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 739)
[M::mem_pestat] mean and std.dev: (267.90, 138.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 932)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (93, 488, 1398)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4008)
[M::mem_pestat] mean and std.dev: (817.03, 939.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5313)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 377, 1332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3642)
[M::mem_pestat] mean and std.dev: (889.28, 974.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4797)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 99, #reads = 1073741 mem = 536879325 peak = 861687808
[M::process] read 697568 sequences (100000168 bp) in 3.240 CPU sec, 3.423 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 284320, 20, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 626, 1637)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4369)
[M::mem_pestat] mean and std.dev: (862.42, 880.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5735)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 240, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 749)
[M::mem_pestat] mean and std.dev: (270.69, 140.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 945)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (492, 821, 1485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3471)
[M::mem_pestat] mean and std.dev: (776.35, 618.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4464)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 353, 1827)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5013)
[M::mem_pestat] mean and std.dev: (865.80, 1028.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6606)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698346 reads in 197.872 CPU sec, 6.294 real sec
[M::process] read 696946 sequences (100000273 bp) in 2.571 CPU sec, 2.621 real sec...
[M::mem_process_seqs] Processed 698004 reads in 133.950 CPU sec, 4.412 real sec
sorting block 100, #reads = 1073909 mem = 536879364 peak = 861687808
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 283665, 20, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 257, 828)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2200)
[M::mem_pestat] mean and std.dev: (656.07, 705.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3477)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 241, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (271.66, 140.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 950)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (429, 878, 954)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2004)
[M::mem_pestat] mean and std.dev: (795.60, 433.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2531)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 385, 784)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1994)
[M::mem_pestat] mean and std.dev: (433.60, 322.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2599)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697252 sequences (100000014 bp) in 2.997 CPU sec, 3.206 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 283425, 30, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 246, 778)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2006)
[M::mem_pestat] mean and std.dev: (487.14, 485.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2620)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 243, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (273.17, 140.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 955)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 663, 938)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2390)
[M::mem_pestat] mean and std.dev: (678.04, 584.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3116)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 354, 1242)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3294)
[M::mem_pestat] mean and std.dev: (723.58, 724.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4320)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697568 reads in 193.104 CPU sec, 6.362 real sec
[M::mem_process_seqs] Processed 696946 reads in 131.208 CPU sec, 4.135 real sec
[M::process] read 697786 sequences (100000092 bp) in 2.981 CPU sec, 3.081 real sec...
sorting block 101, #reads = 1071485 mem = 536879123 peak = 861687808
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 284087, 25, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 465, 863)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2233)
[M::mem_pestat] mean and std.dev: (476.94, 355.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2918)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 242, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 759)
[M::mem_pestat] mean and std.dev: (273.02, 141.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 958)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (94, 498, 1243)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3541)
[M::mem_pestat] mean and std.dev: (734.24, 773.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4690)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 488, 1722)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4658)
[M::mem_pestat] mean and std.dev: (902.52, 969.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6126)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700384 sequences (100000029 bp) in 3.040 CPU sec, 3.214 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 283752, 23, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 634, 1919)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5465)
[M::mem_pestat] mean and std.dev: (1000.20, 1123.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7238)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 238, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 739)
[M::mem_pestat] mean and std.dev: (267.88, 138.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 932)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (463, 875, 2173)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5593)
[M::mem_pestat] mean and std.dev: (1293.87, 1158.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7303)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 327, 663)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1535)
[M::mem_pestat] mean and std.dev: (411.62, 292.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1971)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708134 sequences (100000117 bp) in 1.780 CPU sec, 1.776 real sec...
[M::mem_process_seqs] Processed 697252 reads in 204.095 CPU sec, 6.502 real sec
sorting block 102, #reads = 1072274 mem = 536893008 peak = 861687808
[M::mem_process_seqs] Processed 697786 reads in 137.810 CPU sec, 4.364 real sec
sorting block 103, #reads = 1071079 mem = 536882813 peak = 861687808
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 284710, 22, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 412, 1135)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2993)
[M::mem_pestat] mean and std.dev: (632.64, 586.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3922)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 232, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 724)
[M::mem_pestat] mean and std.dev: (263.10, 136.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 913)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (64, 853, 1936)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5680)
[M::mem_pestat] mean and std.dev: (1126.19, 1299.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7552)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 296, 744)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1746)
[M::mem_pestat] mean and std.dev: (406.03, 286.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2247)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706700 sequences (100000052 bp) in 2.830 CPU sec, 3.052 real sec...
[M::process] read 706982 sequences (100000045 bp) in 1.790 CPU sec, 1.792 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 287407, 21, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 326, 788)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1986)
[M::mem_pestat] mean and std.dev: (383.67, 276.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2585)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 213, 314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 650)
[M::mem_pestat] mean and std.dev: (240.57, 122.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 818)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 902, 2543)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7153)
[M::mem_pestat] mean and std.dev: (1137.81, 957.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9458)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 379, 909)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2277)
[M::mem_pestat] mean and std.dev: (424.67, 276.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2961)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700384 reads in 225.531 CPU sec, 7.307 real sec
[M::mem_process_seqs] Processed 708134 reads in 142.252 CPU sec, 4.537 real sec
sorting block 104, #reads = 1063759 mem = 536880515 peak = 861687808
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 287430, 19, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 418, 673)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1673)
[M::mem_pestat] mean and std.dev: (372.54, 215.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2173)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 215, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 655)
[M::mem_pestat] mean and std.dev: (243.12, 123.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 824)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 647, 1571)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4433)
[M::mem_pestat] mean and std.dev: (781.29, 911.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5864)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 343, 989)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2561)
[M::mem_pestat] mean and std.dev: (580.86, 529.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3347)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706208 sequences (100000017 bp) in 2.733 CPU sec, 2.916 real sec...
[M::process] read 705672 sequences (100000119 bp) in 1.980 CPU sec, 1.983 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 287621, 17, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 308, 979)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2563)
[M::mem_pestat] mean and std.dev: (565.39, 665.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3355)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 215, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 655)
[M::mem_pestat] mean and std.dev: (242.94, 122.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 824)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (603, 917, 1275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2619)
[M::mem_pestat] mean and std.dev: (745.87, 408.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3291)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 257, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1039)
[M::mem_pestat] mean and std.dev: (302.87, 190.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1329)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706700 reads in 209.384 CPU sec, 6.795 real sec
[M::mem_process_seqs] Processed 706982 reads in 138.274 CPU sec, 4.420 real sec
sorting block 105, #reads = 1072526 mem = 536886693 peak = 861687808
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 287530, 12, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 224, 755)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1939)
[M::mem_pestat] mean and std.dev: (307.54, 272.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2531)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 216, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 659)
[M::mem_pestat] mean and std.dev: (244.07, 123.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 829)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 460, 1943)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5423)
[M::mem_pestat] mean and std.dev: (979.36, 1503.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7163)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 348, 644)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1570)
[M::mem_pestat] mean and std.dev: (347.16, 219.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2033)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703222 sequences (100000061 bp) in 3.021 CPU sec, 3.195 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 286909, 24, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 387, 2612)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7480)
[M::mem_pestat] mean and std.dev: (1450.31, 1926.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9914)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 218, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (246.38, 124.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 841)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (366, 1875, 3279)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9105)
[M::mem_pestat] mean and std.dev: (2088.43, 2100.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12018)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (345, 498, 1357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3381)
[M::mem_pestat] mean and std.dev: (765.63, 718.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4393)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701786 sequences (100000257 bp) in 2.230 CPU sec, 2.227 real sec...
[M::mem_process_seqs] Processed 706208 reads in 216.655 CPU sec, 6.897 real sec
sorting block 106, #reads = 1071201 mem = 536886154 peak = 861687808
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 286971, 25, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 224, 705)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1813)
[M::mem_pestat] mean and std.dev: (377.88, 351.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2367)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 225, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (253.92, 129.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 877)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (87, 439, 1663)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4815)
[M::mem_pestat] mean and std.dev: (685.79, 757.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6391)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (433, 630, 1596)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3922)
[M::mem_pestat] mean and std.dev: (1012.48, 942.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5085)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701326 sequences (100000171 bp) in 2.916 CPU sec, 2.921 real sec...
[M::mem_process_seqs] Processed 703222 reads in 114.481 CPU sec, 3.607 real sec
sorting block 107, #reads = 1072232 mem = 536881690 peak = 861687808
[M::mem_process_seqs] Processed 705672 reads in 302.311 CPU sec, 9.582 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 285758, 19, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 337, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 878)
[M::mem_pestat] mean and std.dev: (336.96, 176.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1101)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 229, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 707)
[M::mem_pestat] mean and std.dev: (258.20, 132.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 891)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (355, 672, 1342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3316)
[M::mem_pestat] mean and std.dev: (981.26, 957.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4810)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 273, 969)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2543)
[M::mem_pestat] mean and std.dev: (534.13, 494.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3330)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700870 sequences (100000071 bp) in 2.798 CPU sec, 2.999 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 286069, 22, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 279, 542)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1170)
[M::mem_pestat] mean and std.dev: (353.53, 250.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1484)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 230, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 716)
[M::mem_pestat] mean and std.dev: (259.68, 133.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 903)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (293, 1158, 2254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6176)
[M::mem_pestat] mean and std.dev: (1301.95, 1102.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8137)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 424, 739)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1801)
[M::mem_pestat] mean and std.dev: (428.86, 359.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2332)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701786 reads in 213.555 CPU sec, 6.772 real sec
[M::mem_process_seqs] Processed 701326 reads in 123.906 CPU sec, 3.909 real sec
sorting block 108, #reads = 1070879 mem = 536879721 peak = 861687808
[M::process] read 700808 sequences (100000054 bp) in 2.200 CPU sec, 2.282 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 285591, 22, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 608, 2418)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6758)
[M::mem_pestat] mean and std.dev: (841.52, 949.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8928)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 232, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 723)
[M::mem_pestat] mean and std.dev: (262.01, 135.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 912)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 966, 1193)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3145)
[M::mem_pestat] mean and std.dev: (740.11, 538.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4121)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 482, 969)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2497)
[M::mem_pestat] mean and std.dev: (548.55, 386.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3261)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 109, #reads = 1073506 mem = 536877806 peak = 861687808
[M::process] read 700468 sequences (100000119 bp) in 3.185 CPU sec, 3.474 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 285214, 20, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (341, 506, 1601)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4121)
[M::mem_pestat] mean and std.dev: (722.69, 552.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5381)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 232, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 723)
[M::mem_pestat] mean and std.dev: (261.93, 135.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 912)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (60, 351, 892)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2556)
[M::mem_pestat] mean and std.dev: (383.56, 363.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3388)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 373, 905)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2243)
[M::mem_pestat] mean and std.dev: (518.95, 384.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2912)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700870 reads in 187.512 CPU sec, 5.967 real sec
[M::mem_process_seqs] Processed 700808 reads in 125.956 CPU sec, 3.964 real sec
[M::process] read 699888 sequences (100000230 bp) in 2.581 CPU sec, 2.650 real sec...
sorting block 110, #reads = 1074603 mem = 536880921 peak = 861687808
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 285156, 17, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (262, 586, 2198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6070)
[M::mem_pestat] mean and std.dev: (1617.36, 1957.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9446)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 232, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 724)
[M::mem_pestat] mean and std.dev: (262.84, 136.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 913)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (90, 265, 1288)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3684)
[M::mem_pestat] mean and std.dev: (467.73, 574.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4882)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 480, 642)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1558)
[M::mem_pestat] mean and std.dev: (468.78, 318.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2016)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698960 sequences (100000140 bp) in 3.305 CPU sec, 3.509 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 284745, 27, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 378, 842)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2238)
[M::mem_pestat] mean and std.dev: (512.19, 522.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2936)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 731)
[M::mem_pestat] mean and std.dev: (265.20, 137.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 922)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 345, 1574)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4442)
[M::mem_pestat] mean and std.dev: (757.89, 753.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5876)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 425, 799)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1889)
[M::mem_pestat] mean and std.dev: (489.92, 358.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2434)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700468 reads in 178.223 CPU sec, 5.676 real sec
[M::mem_process_seqs] Processed 699888 reads in 117.799 CPU sec, 3.716 real sec
[M::process] read 698948 sequences (100000073 bp) in 2.694 CPU sec, 2.821 real sec...
sorting block 111, #reads = 1073555 mem = 536877686 peak = 861687808
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 284823, 15, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 460, 975)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2517)
[M::mem_pestat] mean and std.dev: (522.65, 466.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3288)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 237, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 744)
[M::mem_pestat] mean and std.dev: (267.71, 138.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 939)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (396, 505, 2052)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5364)
[M::mem_pestat] mean and std.dev: (1273.07, 1371.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7020)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 197, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 467)
[M::mem_pestat] mean and std.dev: (194.17, 60.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 570)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698144 sequences (100000235 bp) in 2.950 CPU sec, 3.163 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 284898, 35, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 298, 1427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3829)
[M::mem_pestat] mean and std.dev: (568.93, 513.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5030)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 238, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 745)
[M::mem_pestat] mean and std.dev: (268.21, 137.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 940)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (91, 493, 1050)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2968)
[M::mem_pestat] mean and std.dev: (579.13, 500.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3927)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 449, 873)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2133)
[M::mem_pestat] mean and std.dev: (548.41, 358.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2763)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698960 reads in 172.200 CPU sec, 5.486 real sec
[M::mem_process_seqs] Processed 698948 reads in 113.240 CPU sec, 3.576 real sec
sorting block 112, #reads = 1074025 mem = 536878530 peak = 861687808
[M::process] read 698150 sequences (100000058 bp) in 2.636 CPU sec, 2.782 real sec...
sorting block 113, #reads = 1073897 mem = 536879037 peak = 861687808
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 283516, 18, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 304, 416)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 786)
[M::mem_pestat] mean and std.dev: (292.45, 132.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 971)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 242, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (272.74, 141.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 961)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (20, 400, 979)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2897)
[M::mem_pestat] mean and std.dev: (433.33, 544.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3856)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 494, 2126)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5892)
[M::mem_pestat] mean and std.dev: (1314.53, 1603.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7775)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696944 sequences (100000189 bp) in 3.495 CPU sec, 3.835 real sec...
[M::mem_process_seqs] Processed 698150 reads in 94.853 CPU sec, 3.040 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 284517, 21, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 277, 949)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2413)
[M::mem_pestat] mean and std.dev: (476.77, 502.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3145)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 240, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (269.71, 138.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 944)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (323, 1365, 2378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6488)
[M::mem_pestat] mean and std.dev: (1336.63, 1285.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8543)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 378, 833)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2165)
[M::mem_pestat] mean and std.dev: (544.73, 522.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2831)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 284047, 15, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 244, 1307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3533)
[M::mem_pestat] mean and std.dev: (609.90, 667.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4646)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 766)
[M::mem_pestat] mean and std.dev: (274.60, 141.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 967)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (418, 509, 1342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3190)
[M::mem_pestat] mean and std.dev: (659.46, 584.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4114)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (296, 392, 1525)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3983)
[M::mem_pestat] mean and std.dev: (684.62, 596.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5212)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697120 sequences (100000005 bp) in 2.806 CPU sec, 2.995 real sec...
[M::mem_process_seqs] Processed 698144 reads in 261.930 CPU sec, 8.380 real sec
[M::mem_process_seqs] Processed 696944 reads in 111.574 CPU sec, 3.532 real sec
sorting block 114, #reads = 1073817 mem = 536876735 peak = 861687808
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 283608, 27, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (315, 623, 1628)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4254)
[M::mem_pestat] mean and std.dev: (795.32, 819.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5567)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (274.09, 141.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 963)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 656, 1404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3826)
[M::mem_pestat] mean and std.dev: (808.04, 790.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5037)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 364, 1163)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3007)
[M::mem_pestat] mean and std.dev: (654.78, 504.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3929)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697120 reads in 91.221 CPU sec, 3.022 real sec
[M::process] read 696962 sequences (100000107 bp) in 3.773 CPU sec, 4.167 real sec...
sorting block 115, #reads = 1074203 mem = 536878295 peak = 861687808
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 283111, 20, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 338, 617)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1499)
[M::mem_pestat] mean and std.dev: (453.03, 378.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1968)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (272.47, 139.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 951)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (300, 732, 1200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3000)
[M::mem_pestat] mean and std.dev: (639.11, 394.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3900)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 335, 748)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1888)
[M::mem_pestat] mean and std.dev: (359.79, 240.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2458)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696962 reads in 95.725 CPU sec, 3.387 real sec
[M::process] read 695378 sequences (100000292 bp) in 3.440 CPU sec, 3.838 real sec...
[M::process] read 329782 sequences (47237148 bp) in 1.475 CPU sec, 1.566 real sec...
sorting block 116, #reads = 1072098 mem = 536880158 peak = 861687808
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 283555, 37, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 299, 1077)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2919)
[M::mem_pestat] mean and std.dev: (650.80, 582.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3840)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 249, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (276.49, 140.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 965)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1063, 1356, 3683)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8923)
[M::mem_pestat] mean and std.dev: (1820.14, 1271.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11543)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 384, 1082)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2794)
[M::mem_pestat] mean and std.dev: (587.38, 540.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3650)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 134079, 9, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (296, 517, 925)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2183)
[M::mem_pestat] mean and std.dev: (504.00, 421.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2812)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 239, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 739)
[M::mem_pestat] mean and std.dev: (267.88, 136.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 932)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 207, 392)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 812)
[M::mem_pestat] mean and std.dev: (221.94, 86.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1022)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695378 reads in 131.460 CPU sec, 4.459 real sec
[M::mem_process_seqs] Processed 329782 reads in 66.949 CPU sec, 2.167 real sec
sorting block 117, #reads = 1073733 mem = 536878624 peak = 861687808
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 126050682
overall: 69502259200 mem 20983.610 user 1026.654 sys 732.750 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1136_4GR-T1-TDNA-1_A23MHWWLT4_1.L006\tPU:L006\tSM:1136_4GR-T1-TDNA-1_A23MHWWLT4_1\tLB:1136_4GR-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1136_4GR-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1136_4GR-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 732.797 sec; CPU: 22010.272 sec
sorting block 118, #reads = 311257 mem = 156539473 peak = 861687808
uniq header count 1
merging 119 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31 max 384
algo: util-sort
license: sentieon:util=1
output file size: 7403860824
output reads: 127104213
bam_mem_sort: 119 calls 81.066 user 2.413 sys 83.701 real
bam_write: 119 calls 45.752 user 3.103 sys 52.330 real
execute: 1 calls 36.468 user 1.882 sys 777.741 real
merge_files: 1 calls 36.447 user 1.847 sys 44.559 real
parse_chunk: 1893 calls 85.466 user 21.786 sys 109.864 real
read_chunk: 5120 calls 62.442 user 53.087 sys 653.436 real
sort_block: 1 calls 45.909 user 52.520 sys 631.058 real
write_chunk: 3225 calls 35.979 user 1.493 sys 43.445 real
overall: 3024044032 mem 1798.782 user 96.704 sys 777.772 real
ls: cannot access '*.cram': No such file or directory