cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1136_3MV-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 1903.160 CPU sec, 68.888 real sec
[M::process] read 681720 sequences (100000107 bp) in 0.992 CPU sec, 1.001 real sec...
[M::process] read 678256 sequences (100000135 bp) in 1.332 CPU sec, 1.381 real sec...
[M::process] read 678780 sequences (100000165 bp) in 1.594 CPU sec, 1.602 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 282562, 13, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 265, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 942)
[M::mem_pestat] mean and std.dev: (265.97, 123.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1186)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 325, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 950)
[M::mem_pestat] mean and std.dev: (343.90, 166.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1197)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (117, 586, 1244)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3498)
[M::mem_pestat] mean and std.dev: (915.23, 863.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4625)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (283, 408, 473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 853)
[M::mem_pestat] mean and std.dev: (356.21, 144.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1043)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 679552 sequences (100000130 bp) in 1.418 CPU sec, 1.427 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 281107, 11, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 428, 505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1087)
[M::mem_pestat] mean and std.dev: (375.98, 187.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1378)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 354, 485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 995)
[M::mem_pestat] mean and std.dev: (367.91, 171.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1250)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (807, 1089, 7028)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 19470)
[M::mem_pestat] mean and std.dev: (3136.73, 3635.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 25691)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 300, 539)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1233)
[M::mem_pestat] mean and std.dev: (325.00, 172.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1580)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 281138, 20, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 281, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 778)
[M::mem_pestat] mean and std.dev: (272.51, 159.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 982)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 350, 483)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 999)
[M::mem_pestat] mean and std.dev: (364.85, 172.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1257)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (129, 251, 2432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7038)
[M::mem_pestat] mean and std.dev: (998.75, 1590.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9341)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 260, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 578)
[M::mem_pestat] mean and std.dev: (282.04, 109.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 721)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681720 reads in 255.086 CPU sec, 8.177 real sec
[M::mem_process_seqs] Processed 678256 reads in 171.036 CPU sec, 5.513 real sec
[M::mem_process_seqs] Processed 678780 reads in 188.012 CPU sec, 6.068 real sec
sorting block 0, #reads = 1074875 mem = 536880021 peak = 596967424
[M::process] read 680672 sequences (100000037 bp) in 2.252 CPU sec, 2.409 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 281539, 11, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (122, 251, 492)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1232)
[M::mem_pestat] mean and std.dev: (370.14, 295.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1602)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 344, 477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 989)
[M::mem_pestat] mean and std.dev: (359.62, 171.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1245)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (111, 354, 2599)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7575)
[M::mem_pestat] mean and std.dev: (1038.00, 1142.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10063)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 363, 676)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1608)
[M::mem_pestat] mean and std.dev: (396.26, 252.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2074)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680738 sequences (100000222 bp) in 1.650 CPU sec, 1.655 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 281876, 9, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 334, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 846)
[M::mem_pestat] mean and std.dev: (318.67, 134.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1049)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 334, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 981)
[M::mem_pestat] mean and std.dev: (352.63, 170.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1237)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 183, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1006)
[M::mem_pestat] mean and std.dev: (306.09, 226.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1291)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 679552 reads in 162.029 CPU sec, 5.122 real sec
[M::process] read 681440 sequences (100000149 bp) in 1.530 CPU sec, 1.526 real sec...
sorting block 1, #reads = 1074640 mem = 536878815 peak = 839188480
[M::mem_process_seqs] Processed 680672 reads in 104.422 CPU sec, 3.294 real sec
sorting block 2, #reads = 1075958 mem = 536882750 peak = 895557632
[M::process] read 680864 sequences (100000271 bp) in 1.995 CPU sec, 2.091 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 282504, 8, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 395, 1252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3276)
[M::mem_pestat] mean and std.dev: (652.49, 685.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4288)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 333, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 978)
[M::mem_pestat] mean and std.dev: (351.66, 169.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1233)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 332, 576)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1268)
[M::mem_pestat] mean and std.dev: (314.14, 147.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1614)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677658 sequences (100000002 bp) in 1.700 CPU sec, 1.702 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 282393, 5, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (324, 459, 1362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3438)
[M::mem_pestat] mean and std.dev: (710.00, 676.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4476)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 329, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 967)
[M::mem_pestat] mean and std.dev: (347.89, 168.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1219)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 261, 376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 778)
[M::mem_pestat] mean and std.dev: (293.27, 175.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 997)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680738 reads in 161.859 CPU sec, 5.147 real sec
[M::mem_process_seqs] Processed 681440 reads in 103.574 CPU sec, 3.301 real sec
sorting block 3, #reads = 1075965 mem = 536879299 peak = 895557632
[M::process] read 679838 sequences (100000282 bp) in 1.787 CPU sec, 1.916 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 282061, 7, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 286, 831)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2131)
[M::mem_pestat] mean and std.dev: (358.08, 320.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2781)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 333, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 979)
[M::mem_pestat] mean and std.dev: (352.52, 170.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1234)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 352, 513)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1053)
[M::mem_pestat] mean and std.dev: (347.20, 147.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1323)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681396 sequences (100000064 bp) in 1.350 CPU sec, 1.348 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 281159, 11, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 255, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 655)
[M::mem_pestat] mean and std.dev: (272.06, 115.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 803)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 359, 494)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1016)
[M::mem_pestat] mean and std.dev: (373.18, 174.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1277)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1976, 1976, 1976)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1976, 1976)
[M::mem_pestat] mean and std.dev: (1976.00, 0.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1976, 1976)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 431, 499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 995)
[M::mem_pestat] mean and std.dev: (362.71, 143.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1243)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 281846, 8, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 286, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 903)
[M::mem_pestat] mean and std.dev: (307.24, 135.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1130)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 342, 476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 990)
[M::mem_pestat] mean and std.dev: (358.59, 171.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1247)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 348, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 973)
[M::mem_pestat] mean and std.dev: (301.39, 151.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1233)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680864 reads in 229.135 CPU sec, 7.358 real sec
[M::mem_process_seqs] Processed 677658 reads in 170.260 CPU sec, 5.495 real sec
sorting block 4, #reads = 1076702 mem = 536880326 peak = 895557632
[M::mem_process_seqs] Processed 679838 reads in 185.729 CPU sec, 6.012 real sec
sorting block 5, #reads = 1075245 mem = 536884582 peak = 895557632
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 282022, 15, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 311, 729)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1875)
[M::mem_pestat] mean and std.dev: (389.74, 320.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2448)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 330, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 978)
[M::mem_pestat] mean and std.dev: (350.00, 171.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1234)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (106, 594, 2841)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8311)
[M::mem_pestat] mean and std.dev: (1360.53, 1526.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11046)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 362, 569)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1235)
[M::mem_pestat] mean and std.dev: (348.02, 159.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1568)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680520 sequences (100000146 bp) in 2.497 CPU sec, 2.745 real sec...
[M::mem_process_seqs] Processed 681396 reads in 91.338 CPU sec, 3.024 real sec
sorting block 6, #reads = 1077482 mem = 536879971 peak = 895557632
[M::process] read 680540 sequences (100000110 bp) in 2.258 CPU sec, 2.433 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 281719, 8, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 294, 546)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1220)
[M::mem_pestat] mean and std.dev: (336.57, 194.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1557)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 336, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 983)
[M::mem_pestat] mean and std.dev: (353.83, 170.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1239)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 236, 475)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1111)
[M::mem_pestat] mean and std.dev: (322.59, 189.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1429)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680686 sequences (100000240 bp) in 1.700 CPU sec, 1.692 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 281540, 10, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 275, 869)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2263)
[M::mem_pestat] mean and std.dev: (510.21, 468.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2960)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 335, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 980)
[M::mem_pestat] mean and std.dev: (353.67, 170.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1235)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (120, 139, 1306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3678)
[M::mem_pestat] mean and std.dev: (781.70, 955.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4864)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 295, 411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 855)
[M::mem_pestat] mean and std.dev: (311.51, 162.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1077)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 679936 sequences (100000076 bp) in 1.250 CPU sec, 1.251 real sec...
[M::mem_process_seqs] Processed 680520 reads in 164.565 CPU sec, 5.204 real sec
[M::process] read 678428 sequences (100000285 bp) in 1.781 CPU sec, 1.787 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 282278, 9, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 322, 404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 762)
[M::mem_pestat] mean and std.dev: (324.31, 145.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 941)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 332, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 978)
[M::mem_pestat] mean and std.dev: (351.52, 170.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1233)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 275, 376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 774)
[M::mem_pestat] mean and std.dev: (280.18, 136.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 973)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680686 reads in 92.824 CPU sec, 3.138 real sec
sorting block 7, #reads = 1076834 mem = 536878766 peak = 895557632
[M::mem_process_seqs] Processed 680540 reads in 216.887 CPU sec, 7.086 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 281603, 18, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 280, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 713)
[M::mem_pestat] mean and std.dev: (276.24, 112.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 885)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 334, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 972)
[M::mem_pestat] mean and std.dev: (353.00, 169.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1224)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 171, 969)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2615)
[M::mem_pestat] mean and std.dev: (460.25, 549.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3438)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 354, 508)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1108)
[M::mem_pestat] mean and std.dev: (391.15, 241.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1408)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680232 sequences (100000080 bp) in 2.412 CPU sec, 2.562 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 280526, 16, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 283, 423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 887)
[M::mem_pestat] mean and std.dev: (290.73, 137.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1119)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 347, 481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 991)
[M::mem_pestat] mean and std.dev: (363.15, 170.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1246)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 2163, 7349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 21737)
[M::mem_pestat] mean and std.dev: (3566.38, 3278.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 28931)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 384, 663)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1553)
[M::mem_pestat] mean and std.dev: (399.77, 197.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1998)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680840 sequences (100000280 bp) in 1.830 CPU sec, 1.824 real sec...
[M::mem_process_seqs] Processed 679936 reads in 182.906 CPU sec, 5.816 real sec
sorting block 8, #reads = 1075934 mem = 536876826 peak = 895557632
[M::mem_process_seqs] Processed 678428 reads in 108.781 CPU sec, 3.446 real sec
sorting block 9, #reads = 1074916 mem = 536881583 peak = 895557632
[M::process] read 678660 sequences (100000216 bp) in 2.220 CPU sec, 2.371 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 281624, 6, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 255, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 593)
[M::mem_pestat] mean and std.dev: (249.06, 95.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 717)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 329, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 958)
[M::mem_pestat] mean and std.dev: (348.94, 167.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1206)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 301, 433)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 897)
[M::mem_pestat] mean and std.dev: (301.29, 153.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1129)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680064 sequences (100000210 bp) in 1.790 CPU sec, 1.782 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 281655, 7, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 196, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1074)
[M::mem_pestat] mean and std.dev: (254.21, 164.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1383)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 327, 460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 958)
[M::mem_pestat] mean and std.dev: (346.74, 167.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1207)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 294, 473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 947)
[M::mem_pestat] mean and std.dev: (334.24, 170.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1184)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680232 reads in 169.930 CPU sec, 5.410 real sec
[M::mem_process_seqs] Processed 680840 reads in 108.223 CPU sec, 3.452 real sec
sorting block 10, #reads = 1075279 mem = 536877782 peak = 895557632
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 281047, 18, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 272, 544)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1232)
[M::mem_pestat] mean and std.dev: (327.09, 230.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1576)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 346, 479)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 989)
[M::mem_pestat] mean and std.dev: (362.19, 170.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1244)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (115, 331, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1138)
[M::mem_pestat] mean and std.dev: (302.35, 272.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1479)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 262, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 937)
[M::mem_pestat] mean and std.dev: (306.10, 159.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1174)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 679774 sequences (100000061 bp) in 2.604 CPU sec, 2.741 real sec...
[M::process] read 680250 sequences (100000013 bp) in 1.820 CPU sec, 1.822 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 281570, 14, 85)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 287, 528)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1278)
[M::mem_pestat] mean and std.dev: (314.10, 211.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1653)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 330, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 956)
[M::mem_pestat] mean and std.dev: (348.71, 166.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1203)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (249, 485, 560)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1182)
[M::mem_pestat] mean and std.dev: (370.82, 181.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1493)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 348, 541)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1153)
[M::mem_pestat] mean and std.dev: (348.85, 166.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1459)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 678660 reads in 171.798 CPU sec, 5.468 real sec
[M::mem_process_seqs] Processed 680064 reads in 110.219 CPU sec, 3.498 real sec
sorting block 11, #reads = 1075221 mem = 536879192 peak = 895557632
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 281331, 10, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 270, 556)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1260)
[M::mem_pestat] mean and std.dev: (321.19, 174.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1612)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 331, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 953)
[M::mem_pestat] mean and std.dev: (349.11, 166.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1199)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (35, 635, 866)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2528)
[M::mem_pestat] mean and std.dev: (477.60, 473.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3359)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 294, 412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 816)
[M::mem_pestat] mean and std.dev: (309.06, 167.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1018)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 678462 sequences (100000073 bp) in 2.625 CPU sec, 2.754 real sec...
[M::process] read 678464 sequences (100000260 bp) in 1.730 CPU sec, 1.731 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 281820, 21, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 384, 485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1047)
[M::mem_pestat] mean and std.dev: (320.29, 143.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1328)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 328, 460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 954)
[M::mem_pestat] mean and std.dev: (347.47, 166.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1201)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (39, 2588, 8223)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 24591)
[M::mem_pestat] mean and std.dev: (2955.52, 3284.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 32775)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 318, 480)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 990)
[M::mem_pestat] mean and std.dev: (317.62, 165.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1245)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 679774 reads in 169.754 CPU sec, 5.401 real sec
sorting block 12, #reads = 1076244 mem = 536880668 peak = 895557632
[M::mem_process_seqs] Processed 680250 reads in 109.775 CPU sec, 3.489 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 280843, 14, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 293, 474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1034)
[M::mem_pestat] mean and std.dev: (314.43, 171.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1314)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 341, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 970)
[M::mem_pestat] mean and std.dev: (357.72, 168.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1219)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (386, 813, 2405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6443)
[M::mem_pestat] mean and std.dev: (1151.50, 903.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8462)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 284, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 617)
[M::mem_pestat] mean and std.dev: (256.42, 121.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 766)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 13, #reads = 1075618 mem = 536883483 peak = 895557632
[M::process] read 680324 sequences (100000020 bp) in 2.483 CPU sec, 2.617 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 280821, 17, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 312, 758)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1982)
[M::mem_pestat] mean and std.dev: (418.67, 417.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2594)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 342, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 968)
[M::mem_pestat] mean and std.dev: (358.74, 168.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1216)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (345, 685, 1119)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2667)
[M::mem_pestat] mean and std.dev: (742.88, 532.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3441)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 333, 567)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1291)
[M::mem_pestat] mean and std.dev: (431.03, 339.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1789)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680262 sequences (100000257 bp) in 1.750 CPU sec, 1.749 real sec...
[M::mem_process_seqs] Processed 678462 reads in 161.582 CPU sec, 5.130 real sec
[M::mem_process_seqs] Processed 678464 reads in 106.247 CPU sec, 3.365 real sec
sorting block 14, #reads = 1075852 mem = 536881916 peak = 895557632
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 281027, 10, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 239, 1014)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2752)
[M::mem_pestat] mean and std.dev: (400.31, 437.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3621)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 326, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 942)
[M::mem_pestat] mean and std.dev: (345.90, 165.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1185)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 659, 3110)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8886)
[M::mem_pestat] mean and std.dev: (1335.40, 1361.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11774)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 518, 859)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2113)
[M::mem_pestat] mean and std.dev: (509.10, 303.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2740)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 679402 sequences (100000301 bp) in 2.664 CPU sec, 2.810 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 281302, 7, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 327, 526)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1112)
[M::mem_pestat] mean and std.dev: (349.26, 174.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1405)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 328, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 948)
[M::mem_pestat] mean and std.dev: (346.56, 166.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1193)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (311, 359, 581)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1121)
[M::mem_pestat] mean and std.dev: (362.45, 136.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1391)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 679580 sequences (100000202 bp) in 1.780 CPU sec, 1.782 real sec...
[M::mem_process_seqs] Processed 680324 reads in 161.135 CPU sec, 5.103 real sec
[M::mem_process_seqs] Processed 680262 reads in 105.078 CPU sec, 3.324 real sec
sorting block 15, #reads = 1076051 mem = 536883602 peak = 895557632
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281445, 12, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (276, 490, 834)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1950)
[M::mem_pestat] mean and std.dev: (468.38, 274.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2508)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 335, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 957)
[M::mem_pestat] mean and std.dev: (352.63, 167.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1203)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (711, 2550, 3126)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7956)
[M::mem_pestat] mean and std.dev: (1800.83, 1185.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10371)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 276, 406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 870)
[M::mem_pestat] mean and std.dev: (301.77, 151.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1102)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680220 sequences (100000220 bp) in 2.761 CPU sec, 2.937 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 281332, 24, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 318, 493)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1031)
[M::mem_pestat] mean and std.dev: (334.48, 173.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1300)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 333, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 961)
[M::mem_pestat] mean and std.dev: (352.05, 168.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1209)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 316, 1280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3520)
[M::mem_pestat] mean and std.dev: (593.21, 722.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4640)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (290, 470, 1105)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2735)
[M::mem_pestat] mean and std.dev: (453.33, 304.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3550)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 679402 reads in 156.308 CPU sec, 4.943 real sec
[M::process] read 679918 sequences (100000000 bp) in 1.867 CPU sec, 1.868 real sec...
[M::mem_process_seqs] Processed 679580 reads in 102.186 CPU sec, 3.226 real sec
sorting block 16, #reads = 1075562 mem = 536879516 peak = 895557632
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 282180, 21, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (255, 404, 496)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 978)
[M::mem_pestat] mean and std.dev: (368.31, 200.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1219)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 333, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 968)
[M::mem_pestat] mean and std.dev: (352.01, 169.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1219)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (105, 1765, 2599)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7587)
[M::mem_pestat] mean and std.dev: (1440.19, 1164.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10081)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 400, 853)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2145)
[M::mem_pestat] mean and std.dev: (518.16, 388.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2791)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 679190 sequences (100000234 bp) in 2.786 CPU sec, 2.965 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 281985, 15, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 335, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 872)
[M::mem_pestat] mean and std.dev: (327.11, 145.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1083)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 334, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 972)
[M::mem_pestat] mean and std.dev: (353.20, 169.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1224)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1200, 2018, 2018)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3654)
[M::mem_pestat] mean and std.dev: (1585.13, 626.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4472)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 282, 520)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1184)
[M::mem_pestat] mean and std.dev: (288.83, 142.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1516)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680220 reads in 155.813 CPU sec, 4.938 real sec
[M::process] read 680006 sequences (100000121 bp) in 1.961 CPU sec, 1.990 real sec...
[M::mem_process_seqs] Processed 679918 reads in 101.285 CPU sec, 3.187 real sec
sorting block 17, #reads = 1075250 mem = 536879437 peak = 895557632
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 280954, 9, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 300, 517)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1179)
[M::mem_pestat] mean and std.dev: (283.60, 128.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1510)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 338, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 978)
[M::mem_pestat] mean and std.dev: (357.09, 171.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1231)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 264, 573)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1265)
[M::mem_pestat] mean and std.dev: (349.64, 271.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1611)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 18, #reads = 1076457 mem = 536879420 peak = 895557632
[M::process] read 680500 sequences (100000267 bp) in 2.734 CPU sec, 2.918 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 281515, 13, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 281, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 947)
[M::mem_pestat] mean and std.dev: (286.64, 129.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1200)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 336, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 964)
[M::mem_pestat] mean and std.dev: (352.99, 168.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1213)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (311, 825, 2609)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7205)
[M::mem_pestat] mean and std.dev: (1255.17, 1087.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9503)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 341, 491)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1047)
[M::mem_pestat] mean and std.dev: (326.39, 161.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1325)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 679190 reads in 154.053 CPU sec, 4.895 real sec
[M::mem_process_seqs] Processed 680006 reads in 100.690 CPU sec, 3.170 real sec
[M::process] read 679940 sequences (100000017 bp) in 2.029 CPU sec, 2.065 real sec...
sorting block 19, #reads = 1074540 mem = 536878781 peak = 895557632
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281732, 13, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 265, 986)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2528)
[M::mem_pestat] mean and std.dev: (640.60, 752.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3652)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 334, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 965)
[M::mem_pestat] mean and std.dev: (352.23, 170.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1215)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 429, 1590)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4296)
[M::mem_pestat] mean and std.dev: (1027.92, 1085.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5649)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 253, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 718)
[M::mem_pestat] mean and std.dev: (257.55, 101.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 900)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 679096 sequences (100000073 bp) in 2.645 CPU sec, 2.806 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 281574, 18, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 310, 704)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1746)
[M::mem_pestat] mean and std.dev: (351.66, 228.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2267)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 337, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 971)
[M::mem_pestat] mean and std.dev: (354.75, 170.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1222)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (70, 765, 2633)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7759)
[M::mem_pestat] mean and std.dev: (1092.62, 1104.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10322)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 375, 672)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1532)
[M::mem_pestat] mean and std.dev: (497.41, 378.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2011)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680500 reads in 152.815 CPU sec, 4.855 real sec
[M::process] read 680248 sequences (100000017 bp) in 1.880 CPU sec, 1.912 real sec...
[M::mem_process_seqs] Processed 679940 reads in 99.273 CPU sec, 3.125 real sec
sorting block 20, #reads = 1076636 mem = 536881358 peak = 895557632
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 281402, 14, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 394, 564)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1344)
[M::mem_pestat] mean and std.dev: (324.67, 177.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1734)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 348, 480)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 992)
[M::mem_pestat] mean and std.dev: (363.35, 173.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1248)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (262, 861, 2707)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7597)
[M::mem_pestat] mean and std.dev: (1417.07, 1307.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10042)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (313, 455, 790)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1744)
[M::mem_pestat] mean and std.dev: (562.14, 334.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2221)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 679590 sequences (100000013 bp) in 2.643 CPU sec, 2.799 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 281850, 8, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 276, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 663)
[M::mem_pestat] mean and std.dev: (241.87, 99.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 824)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 338, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 979)
[M::mem_pestat] mean and std.dev: (355.62, 171.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1233)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 484, 788)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1854)
[M::mem_pestat] mean and std.dev: (487.37, 310.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2387)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 679096 reads in 152.195 CPU sec, 4.834 real sec
[M::process] read 679492 sequences (100000152 bp) in 1.829 CPU sec, 1.858 real sec...
[M::mem_process_seqs] Processed 680248 reads in 99.625 CPU sec, 3.134 real sec
sorting block 21, #reads = 1077543 mem = 536879243 peak = 895557632
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 281935, 8, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 293, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 740)
[M::mem_pestat] mean and std.dev: (233.88, 105.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 936)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 344, 477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 991)
[M::mem_pestat] mean and std.dev: (360.76, 173.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1248)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (281, 442, 758)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1712)
[M::mem_pestat] mean and std.dev: (455.18, 277.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2189)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680062 sequences (100000152 bp) in 2.675 CPU sec, 2.849 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 281282, 13, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (272, 333, 482)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 902)
[M::mem_pestat] mean and std.dev: (365.17, 171.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1112)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 344, 476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 986)
[M::mem_pestat] mean and std.dev: (360.22, 172.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1241)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (101, 1712, 2295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6683)
[M::mem_pestat] mean and std.dev: (1371.85, 1050.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8877)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 336, 527)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1111)
[M::mem_pestat] mean and std.dev: (382.28, 218.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1403)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 679590 reads in 150.648 CPU sec, 4.791 real sec
sorting block 22, #reads = 1077021 mem = 536879546 peak = 895557632
[M::process] read 679826 sequences (100000028 bp) in 1.663 CPU sec, 1.686 real sec...
[M::mem_process_seqs] Processed 679492 reads in 97.653 CPU sec, 3.080 real sec
sorting block 23, #reads = 1076916 mem = 536879414 peak = 895557632
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 281926, 4, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 328, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1060)
[M::mem_pestat] mean and std.dev: (282.02, 135.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1354)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 336, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 972)
[M::mem_pestat] mean and std.dev: (353.96, 170.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1224)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (259, 389, 544)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1114)
[M::mem_pestat] mean and std.dev: (336.15, 136.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1399)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 678556 sequences (100000158 bp) in 2.290 CPU sec, 2.427 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 281505, 4, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 262, 474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 996)
[M::mem_pestat] mean and std.dev: (318.83, 168.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1257)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 340, 475)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 987)
[M::mem_pestat] mean and std.dev: (358.28, 173.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1243)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 355, 410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 744)
[M::mem_pestat] mean and std.dev: (326.71, 101.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 911)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680216 sequences (100000215 bp) in 1.390 CPU sec, 1.384 real sec...
[M::mem_process_seqs] Processed 680062 reads in 148.531 CPU sec, 4.726 real sec
[M::mem_process_seqs] Processed 679826 reads in 96.776 CPU sec, 3.069 real sec
sorting block 24, #reads = 1077921 mem = 536879700 peak = 895557632
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 281341, 15, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 270, 404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 902)
[M::mem_pestat] mean and std.dev: (257.62, 115.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1151)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 351, 482)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 992)
[M::mem_pestat] mean and std.dev: (365.84, 173.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1247)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (2420, 2745, 9012)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 22196)
[M::mem_pestat] mean and std.dev: (4095.93, 3070.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 28788)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 288, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 588)
[M::mem_pestat] mean and std.dev: (273.07, 74.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 709)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680484 sequences (100000213 bp) in 2.768 CPU sec, 2.950 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 281424, 7, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (284, 519, 893)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2111)
[M::mem_pestat] mean and std.dev: (602.03, 431.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2720)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 338, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 979)
[M::mem_pestat] mean and std.dev: (355.63, 171.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1233)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 349, 496)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1138)
[M::mem_pestat] mean and std.dev: (335.74, 214.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1459)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 678556 reads in 150.423 CPU sec, 4.761 real sec
[M::process] read 680096 sequences (100000027 bp) in 1.837 CPU sec, 1.847 real sec...
[M::mem_process_seqs] Processed 680216 reads in 99.117 CPU sec, 3.126 real sec
sorting block 25, #reads = 1076320 mem = 536884599 peak = 895557632
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 282700, 3, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 330, 416)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 972)
[M::mem_pestat] mean and std.dev: (295.47, 201.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1250)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 337, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 981)
[M::mem_pestat] mean and std.dev: (355.23, 172.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1236)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 326, 627)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1371)
[M::mem_pestat] mean and std.dev: (368.33, 231.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1743)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680124 sequences (100000245 bp) in 2.645 CPU sec, 2.773 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 281998, 15, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 253, 415)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 875)
[M::mem_pestat] mean and std.dev: (220.00, 79.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1105)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 338, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 977)
[M::mem_pestat] mean and std.dev: (356.06, 171.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1230)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 629, 1061)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2805)
[M::mem_pestat] mean and std.dev: (638.93, 558.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3677)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (295, 392, 961)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2293)
[M::mem_pestat] mean and std.dev: (566.10, 527.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2959)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680014 sequences (100000172 bp) in 1.720 CPU sec, 1.722 real sec...
[M::mem_process_seqs] Processed 680484 reads in 152.076 CPU sec, 4.813 real sec
sorting block 26, #reads = 1077379 mem = 536878756 peak = 895557632
[M::mem_process_seqs] Processed 680096 reads in 99.214 CPU sec, 3.133 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 282741, 13, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 303, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 716)
[M::mem_pestat] mean and std.dev: (242.53, 98.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 893)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 337, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 976)
[M::mem_pestat] mean and std.dev: (355.38, 171.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1229)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 240, 1377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3651)
[M::mem_pestat] mean and std.dev: (594.23, 572.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4788)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 319, 487)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1035)
[M::mem_pestat] mean and std.dev: (311.38, 111.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1309)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 678976 sequences (100000200 bp) in 2.498 CPU sec, 2.686 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 282200, 13, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (132, 285, 2975)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8661)
[M::mem_pestat] mean and std.dev: (1655.27, 2486.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11603)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 339, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 982)
[M::mem_pestat] mean and std.dev: (356.56, 172.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1237)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (4, 4, 1194)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3574)
[M::mem_pestat] mean and std.dev: (393.50, 548.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4764)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 396, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 881)
[M::mem_pestat] mean and std.dev: (343.03, 126.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1089)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 677414 sequences (100000071 bp) in 1.440 CPU sec, 1.431 real sec...
[M::mem_process_seqs] Processed 680124 reads in 153.610 CPU sec, 4.884 real sec
sorting block 27, #reads = 1077481 mem = 536880828 peak = 895557632
[M::mem_process_seqs] Processed 680014 reads in 98.968 CPU sec, 3.135 real sec
sorting block 28, #reads = 1077878 mem = 536877150 peak = 904241152
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 281275, 15, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (260, 375, 798)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1874)
[M::mem_pestat] mean and std.dev: (473.68, 355.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2412)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 340, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 971)
[M::mem_pestat] mean and std.dev: (357.82, 170.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1221)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (87, 686, 955)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2691)
[M::mem_pestat] mean and std.dev: (527.87, 386.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3559)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 326, 649)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1513)
[M::mem_pestat] mean and std.dev: (435.84, 284.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1945)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 679750 sequences (100000113 bp) in 2.619 CPU sec, 2.777 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 280324, 6, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 216, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 561)
[M::mem_pestat] mean and std.dev: (234.83, 90.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 693)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 357, 489)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 999)
[M::mem_pestat] mean and std.dev: (372.26, 174.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1254)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 203, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1118)
[M::mem_pestat] mean and std.dev: (317.52, 248.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1441)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680180 sequences (100000014 bp) in 1.518 CPU sec, 1.517 real sec...
[M::mem_process_seqs] Processed 678976 reads in 150.616 CPU sec, 4.778 real sec
[M::mem_process_seqs] Processed 677414 reads in 96.698 CPU sec, 3.054 real sec
sorting block 29, #reads = 1076454 mem = 536879348 peak = 904241152
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281647, 15, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 286, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1000)
[M::mem_pestat] mean and std.dev: (314.23, 197.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1276)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 336, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 968)
[M::mem_pestat] mean and std.dev: (354.59, 170.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1218)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 913, 1725)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4681)
[M::mem_pestat] mean and std.dev: (907.64, 1037.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6159)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 248, 387)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 815)
[M::mem_pestat] mean and std.dev: (279.70, 126.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1029)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 679630 sequences (100000270 bp) in 2.252 CPU sec, 2.416 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 281617, 5, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 282, 711)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1683)
[M::mem_pestat] mean and std.dev: (433.62, 393.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2169)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 332, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 965)
[M::mem_pestat] mean and std.dev: (351.33, 169.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1215)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 348, 480)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 964)
[M::mem_pestat] mean and std.dev: (371.30, 213.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1226)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680278 sequences (100000036 bp) in 1.770 CPU sec, 1.775 real sec...
[M::mem_process_seqs] Processed 679750 reads in 148.951 CPU sec, 4.725 real sec
[M::mem_process_seqs] Processed 680180 reads in 96.771 CPU sec, 3.063 real sec
sorting block 30, #reads = 1075471 mem = 536889140 peak = 904241152
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 281353, 12, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (275, 326, 572)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1166)
[M::mem_pestat] mean and std.dev: (379.40, 205.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1463)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 338, 475)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 989)
[M::mem_pestat] mean and std.dev: (358.09, 173.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1246)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (361, 1453, 6706)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 19396)
[M::mem_pestat] mean and std.dev: (2167.92, 2668.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 25741)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (270, 333, 503)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 969)
[M::mem_pestat] mean and std.dev: (337.56, 156.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1202)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680338 sequences (100000129 bp) in 2.743 CPU sec, 2.900 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 282301, 13, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 284, 388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 812)
[M::mem_pestat] mean and std.dev: (315.23, 159.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1024)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 333, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 979)
[M::mem_pestat] mean and std.dev: (353.61, 172.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1234)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (282, 482, 853)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1995)
[M::mem_pestat] mean and std.dev: (552.92, 328.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2566)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 433, 2087)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5865)
[M::mem_pestat] mean and std.dev: (835.94, 1096.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7754)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 679630 reads in 150.994 CPU sec, 4.787 real sec
[M::process] read 680300 sequences (100000146 bp) in 1.999 CPU sec, 2.030 real sec...
[M::mem_process_seqs] Processed 680278 reads in 100.361 CPU sec, 3.157 real sec
sorting block 31, #reads = 1076264 mem = 536877949 peak = 904241152
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 281726, 9, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (266, 411, 646)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1406)
[M::mem_pestat] mean and std.dev: (417.41, 208.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1786)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 333, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 976)
[M::mem_pestat] mean and std.dev: (353.44, 172.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1230)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 283, 423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 817)
[M::mem_pestat] mean and std.dev: (299.43, 115.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1014)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 32, #reads = 1077246 mem = 536879936 peak = 904241152
[M::process] read 678292 sequences (100000287 bp) in 2.750 CPU sec, 2.932 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 281357, 7, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 210, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (223.83, 89.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 861)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 327, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 948)
[M::mem_pestat] mean and std.dev: (347.57, 168.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1193)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 260, 395)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 769)
[M::mem_pestat] mean and std.dev: (281.31, 134.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 956)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680338 reads in 161.978 CPU sec, 5.160 real sec
[M::process] read 678948 sequences (100000216 bp) in 2.005 CPU sec, 2.032 real sec...
[M::mem_process_seqs] Processed 680300 reads in 110.175 CPU sec, 3.474 real sec
sorting block 33, #reads = 1077594 mem = 536877610 peak = 904241152
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 280882, 8, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (309, 440, 1713)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4521)
[M::mem_pestat] mean and std.dev: (655.58, 659.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5925)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 345, 476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 978)
[M::mem_pestat] mean and std.dev: (362.07, 171.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1229)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 354, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 826)
[M::mem_pestat] mean and std.dev: (333.00, 152.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1020)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680316 sequences (100000276 bp) in 2.578 CPU sec, 2.712 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 281967, 5, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 337, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 895)
[M::mem_pestat] mean and std.dev: (309.45, 114.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1119)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 338, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 971)
[M::mem_pestat] mean and std.dev: (357.33, 170.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1221)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 283, 689)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1675)
[M::mem_pestat] mean and std.dev: (390.70, 280.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2168)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680146 sequences (100000049 bp) in 1.705 CPU sec, 1.709 real sec...
[M::mem_process_seqs] Processed 678292 reads in 166.919 CPU sec, 5.316 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 282170, 16, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 349, 484)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1020)
[M::mem_pestat] mean and std.dev: (325.11, 160.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1288)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 329, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 957)
[M::mem_pestat] mean and std.dev: (349.25, 169.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1205)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (409, 567, 1532)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3778)
[M::mem_pestat] mean and std.dev: (693.36, 498.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4901)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 263, 519)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1129)
[M::mem_pestat] mean and std.dev: (360.30, 222.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1434)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680264 sequences (100000172 bp) in 2.222 CPU sec, 2.231 real sec...
[M::mem_process_seqs] Processed 680316 reads in 96.005 CPU sec, 3.225 real sec
sorting block 34, #reads = 1074791 mem = 536879206 peak = 904241152
[M::mem_process_seqs] Processed 678948 reads in 231.435 CPU sec, 7.527 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 281704, 20, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 301, 660)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1500)
[M::mem_pestat] mean and std.dev: (405.70, 248.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1920)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 330, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 958)
[M::mem_pestat] mean and std.dev: (350.10, 169.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1206)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 641, 2403)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6903)
[M::mem_pestat] mean and std.dev: (1026.65, 1125.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9153)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 538, 962)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2374)
[M::mem_pestat] mean and std.dev: (534.62, 389.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3080)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 35, #reads = 1076032 mem = 536878525 peak = 961642496
[M::process] read 680098 sequences (100000145 bp) in 3.178 CPU sec, 3.365 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 281536, 11, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 245, 492)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1128)
[M::mem_pestat] mean and std.dev: (364.27, 263.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1446)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 330, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 955)
[M::mem_pestat] mean and std.dev: (349.65, 169.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1202)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (254, 262, 1076)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2720)
[M::mem_pestat] mean and std.dev: (480.20, 451.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3542)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 321, 408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 802)
[M::mem_pestat] mean and std.dev: (275.10, 100.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 999)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680146 reads in 179.357 CPU sec, 5.697 real sec
[M::mem_process_seqs] Processed 680264 reads in 105.435 CPU sec, 3.331 real sec
[M::process] read 680924 sequences (100000163 bp) in 2.507 CPU sec, 2.648 real sec...
sorting block 36, #reads = 1076547 mem = 536877295 peak = 961642496
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 281675, 10, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 203, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 663)
[M::mem_pestat] mean and std.dev: (216.09, 92.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 330, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 958)
[M::mem_pestat] mean and std.dev: (349.85, 168.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1206)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 799, 1620)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4380)
[M::mem_pestat] mean and std.dev: (862.78, 813.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5760)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 282, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 981)
[M::mem_pestat] mean and std.dev: (308.93, 187.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1251)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680656 sequences (100000014 bp) in 2.420 CPU sec, 2.555 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 281986, 15, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 243, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 747)
[M::mem_pestat] mean and std.dev: (264.49, 126.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 940)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 330, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 969)
[M::mem_pestat] mean and std.dev: (350.47, 170.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1221)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 497, 4810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 14086)
[M::mem_pestat] mean and std.dev: (1558.27, 1976.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 18724)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 234, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 943)
[M::mem_pestat] mean and std.dev: (276.59, 177.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1195)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680098 reads in 160.295 CPU sec, 5.092 real sec
[M::mem_process_seqs] Processed 680924 reads in 106.212 CPU sec, 3.344 real sec
[M::process] read 680532 sequences (100000025 bp) in 2.312 CPU sec, 2.409 real sec...
sorting block 37, #reads = 1075941 mem = 536883710 peak = 961642496
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 282386, 11, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (262, 346, 540)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1096)
[M::mem_pestat] mean and std.dev: (317.74, 128.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1374)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 331, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 972)
[M::mem_pestat] mean and std.dev: (351.59, 171.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1225)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (472, 472, 1822)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4522)
[M::mem_pestat] mean and std.dev: (1084.27, 1233.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6020)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 293, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 958)
[M::mem_pestat] mean and std.dev: (325.70, 157.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1204)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681940 sequences (100000096 bp) in 2.649 CPU sec, 2.789 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 281722, 13, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 293, 552)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1228)
[M::mem_pestat] mean and std.dev: (351.72, 226.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1566)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 328, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 962)
[M::mem_pestat] mean and std.dev: (348.67, 169.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1212)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (252, 457, 670)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1506)
[M::mem_pestat] mean and std.dev: (359.91, 205.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1924)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 292, 393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (300.65, 119.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 930)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680656 reads in 158.427 CPU sec, 5.041 real sec
[M::mem_process_seqs] Processed 680532 reads in 106.359 CPU sec, 3.349 real sec
sorting block 38, #reads = 1075898 mem = 536879458 peak = 961642496
[M::process] read 680968 sequences (100000238 bp) in 2.222 CPU sec, 2.287 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 283065, 17, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 269, 608)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1446)
[M::mem_pestat] mean and std.dev: (291.18, 176.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1865)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 322, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 934)
[M::mem_pestat] mean and std.dev: (340.32, 163.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1176)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (917, 1366, 2757)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6437)
[M::mem_pestat] mean and std.dev: (1851.88, 1059.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8277)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 392, 498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1132)
[M::mem_pestat] mean and std.dev: (371.66, 213.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1449)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 39, #reads = 1075020 mem = 536878338 peak = 961642496
[M::process] read 681522 sequences (100000039 bp) in 2.215 CPU sec, 2.346 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 281567, 9, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 379, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 900)
[M::mem_pestat] mean and std.dev: (319.40, 141.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1132)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 329, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 936)
[M::mem_pestat] mean and std.dev: (344.17, 162.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1177)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 318, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 781)
[M::mem_pestat] mean and std.dev: (292.96, 127.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 988)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680722 sequences (100000038 bp) in 1.815 CPU sec, 1.839 real sec...
[M::mem_process_seqs] Processed 681940 reads in 171.682 CPU sec, 5.497 real sec
[M::mem_process_seqs] Processed 680968 reads in 113.855 CPU sec, 3.638 real sec
sorting block 40, #reads = 1075066 mem = 536878094 peak = 961642496
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 281796, 16, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 328, 568)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1338)
[M::mem_pestat] mean and std.dev: (359.22, 244.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1723)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 327, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 937)
[M::mem_pestat] mean and std.dev: (342.73, 163.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1179)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (695, 731, 1898)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4304)
[M::mem_pestat] mean and std.dev: (1194.06, 989.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5507)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 262, 488)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 962)
[M::mem_pestat] mean and std.dev: (300.96, 142.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1199)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680294 sequences (100000164 bp) in 2.880 CPU sec, 3.112 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 282614, 1, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 408, 607)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1331)
[M::mem_pestat] mean and std.dev: (376.47, 200.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1693)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 331, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 943)
[M::mem_pestat] mean and std.dev: (346.59, 163.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1186)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 420, 560)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1170)
[M::mem_pestat] mean and std.dev: (406.82, 184.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1475)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681522 reads in 173.999 CPU sec, 5.627 real sec
[M::process] read 679738 sequences (100000271 bp) in 1.615 CPU sec, 1.700 real sec...
[M::mem_process_seqs] Processed 680722 reads in 114.641 CPU sec, 3.697 real sec
sorting block 41, #reads = 1074959 mem = 536884015 peak = 961642496
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 281800, 5, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 368, 951)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2381)
[M::mem_pestat] mean and std.dev: (631.08, 454.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3096)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 333, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 942)
[M::mem_pestat] mean and std.dev: (347.75, 163.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1184)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 306, 584)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1400)
[M::mem_pestat] mean and std.dev: (379.05, 224.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1808)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677924 sequences (100000025 bp) in 2.656 CPU sec, 3.094 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 281278, 6, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 334, 1430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3834)
[M::mem_pestat] mean and std.dev: (592.97, 566.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5036)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 338, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 967)
[M::mem_pestat] mean and std.dev: (353.32, 167.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1217)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 288, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1038)
[M::mem_pestat] mean and std.dev: (297.58, 167.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1332)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680294 reads in 173.490 CPU sec, 5.606 real sec
[M::process] read 678830 sequences (100000018 bp) in 1.882 CPU sec, 1.898 real sec...
[M::mem_process_seqs] Processed 679738 reads in 116.357 CPU sec, 3.744 real sec
sorting block 42, #reads = 1076423 mem = 536879306 peak = 961642496
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 281030, 8, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 221, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 556)
[M::mem_pestat] mean and std.dev: (239.73, 99.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 672)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 358, 486)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 994)
[M::mem_pestat] mean and std.dev: (369.44, 171.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1248)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 272, 392)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 716)
[M::mem_pestat] mean and std.dev: (292.90, 108.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 878)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680788 sequences (100000153 bp) in 2.579 CPU sec, 2.855 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 281356, 8, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 306, 803)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2023)
[M::mem_pestat] mean and std.dev: (475.59, 371.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2633)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 347, 475)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 975)
[M::mem_pestat] mean and std.dev: (360.58, 168.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1225)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (270, 395, 607)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1281)
[M::mem_pestat] mean and std.dev: (463.76, 224.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1618)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 677924 reads in 172.862 CPU sec, 5.609 real sec
[M::process] read 680912 sequences (100000219 bp) in 1.641 CPU sec, 1.687 real sec...
sorting block 43, #reads = 1075692 mem = 536879292 peak = 961642496
[M::mem_process_seqs] Processed 678830 reads in 113.228 CPU sec, 3.660 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 282252, 12, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 400, 632)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1494)
[M::mem_pestat] mean and std.dev: (340.67, 181.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1925)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 329, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 950)
[M::mem_pestat] mean and std.dev: (346.96, 166.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1196)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 2452, 2601)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7529)
[M::mem_pestat] mean and std.dev: (1658.42, 1371.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9993)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 326, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 917)
[M::mem_pestat] mean and std.dev: (330.15, 155.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1144)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 44, #reads = 1075215 mem = 536880950 peak = 990425088
[M::process] read 680528 sequences (100000255 bp) in 2.809 CPU sec, 3.098 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 282291, 21, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 231, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (7, 497)
[M::mem_pestat] mean and std.dev: (235.53, 97.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 626)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 333, 464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 966)
[M::mem_pestat] mean and std.dev: (350.51, 168.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1217)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (297, 725, 4006)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11424)
[M::mem_pestat] mean and std.dev: (1449.48, 1483.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 15133)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 319, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 908)
[M::mem_pestat] mean and std.dev: (331.43, 175.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1137)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680606 sequences (100000037 bp) in 1.846 CPU sec, 1.852 real sec...
[M::mem_process_seqs] Processed 680788 reads in 175.222 CPU sec, 5.791 real sec
[M::mem_process_seqs] Processed 680912 reads in 114.639 CPU sec, 3.837 real sec
sorting block 45, #reads = 1076509 mem = 536877926 peak = 990425088
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 281833, 8, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 210, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1118)
[M::mem_pestat] mean and std.dev: (317.52, 239.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1441)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 334, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 959)
[M::mem_pestat] mean and std.dev: (350.25, 167.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1207)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 400, 464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 878)
[M::mem_pestat] mean and std.dev: (347.11, 132.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1085)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680400 sequences (100000178 bp) in 2.817 CPU sec, 3.183 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 282078, 8, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 282, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 883)
[M::mem_pestat] mean and std.dev: (277.55, 113.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1104)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 333, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 959)
[M::mem_pestat] mean and std.dev: (349.45, 166.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1207)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 343, 548)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1230)
[M::mem_pestat] mean and std.dev: (347.19, 188.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1571)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680528 reads in 173.904 CPU sec, 5.645 real sec
[M::process] read 680408 sequences (100000281 bp) in 1.756 CPU sec, 1.856 real sec...
[M::mem_process_seqs] Processed 680606 reads in 114.634 CPU sec, 3.729 real sec
sorting block 46, #reads = 1077326 mem = 536884971 peak = 990425088
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 281728, 8, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 294, 732)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1840)
[M::mem_pestat] mean and std.dev: (337.21, 231.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2394)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 333, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 956)
[M::mem_pestat] mean and std.dev: (350.16, 167.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1203)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 314, 413)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 849)
[M::mem_pestat] mean and std.dev: (298.81, 157.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1067)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680240 sequences (100000212 bp) in 2.704 CPU sec, 3.073 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 281931, 11, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 401, 864)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2266)
[M::mem_pestat] mean and std.dev: (552.17, 464.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2967)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 335, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 972)
[M::mem_pestat] mean and std.dev: (352.69, 169.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1224)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (623, 770, 2003)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4763)
[M::mem_pestat] mean and std.dev: (745.56, 481.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6143)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 306, 417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 869)
[M::mem_pestat] mean and std.dev: (321.21, 163.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1095)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680400 reads in 176.879 CPU sec, 5.723 real sec
[M::process] read 678290 sequences (100000117 bp) in 1.997 CPU sec, 2.023 real sec...
[M::mem_process_seqs] Processed 680408 reads in 117.197 CPU sec, 3.795 real sec
sorting block 47, #reads = 1076996 mem = 536881283 peak = 990425088
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 282059, 5, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 206, 403)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 895)
[M::mem_pestat] mean and std.dev: (295.11, 202.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1141)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 337, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 978)
[M::mem_pestat] mean and std.dev: (354.43, 170.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1232)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 268, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (269.57, 135.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 678212 sequences (100000180 bp) in 2.618 CPU sec, 3.214 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 280382, 18, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 307, 557)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1199)
[M::mem_pestat] mean and std.dev: (369.15, 190.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1520)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 349, 478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 978)
[M::mem_pestat] mean and std.dev: (362.85, 169.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1228)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (280, 350, 1376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3568)
[M::mem_pestat] mean and std.dev: (638.76, 565.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4664)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 263, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 665)
[M::mem_pestat] mean and std.dev: (273.62, 124.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 818)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680240 reads in 176.667 CPU sec, 5.963 real sec
sorting block 48, #reads = 1077221 mem = 536880767 peak = 990425088
[M::mem_process_seqs] Processed 678290 reads in 117.174 CPU sec, 3.839 real sec
[M::process] read 680130 sequences (100000061 bp) in 2.001 CPU sec, 2.355 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 281244, 17, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 253, 403)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 833)
[M::mem_pestat] mean and std.dev: (261.26, 108.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1048)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 351, 479)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 979)
[M::mem_pestat] mean and std.dev: (364.68, 169.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1229)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (2, 34, 651)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1949)
[M::mem_pestat] mean and std.dev: (197.44, 258.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2598)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (268, 310, 594)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1246)
[M::mem_pestat] mean and std.dev: (408.91, 199.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1572)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 49, #reads = 1075054 mem = 536879403 peak = 990425088
[M::process] read 680030 sequences (100000011 bp) in 2.519 CPU sec, 2.982 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 281378, 10, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 257, 506)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1202)
[M::mem_pestat] mean and std.dev: (347.58, 257.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1550)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 333, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 957)
[M::mem_pestat] mean and std.dev: (350.41, 167.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1204)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (918, 918, 2076)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4392)
[M::mem_pestat] mean and std.dev: (1233.56, 944.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5550)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 314, 475)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 931)
[M::mem_pestat] mean and std.dev: (313.45, 150.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1159)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 678212 reads in 174.286 CPU sec, 5.835 real sec
[M::mem_process_seqs] Processed 680130 reads in 117.189 CPU sec, 3.883 real sec
[M::process] read 679862 sequences (100000205 bp) in 2.168 CPU sec, 2.590 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 281164, 7, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 288, 552)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1314)
[M::mem_pestat] mean and std.dev: (364.24, 270.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1695)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 335, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 972)
[M::mem_pestat] mean and std.dev: (353.42, 169.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1224)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 265, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 965)
[M::mem_pestat] mean and std.dev: (309.79, 178.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1226)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 50, #reads = 1075902 mem = 536879516 peak = 990425088
[M::process] read 679850 sequences (100000001 bp) in 2.521 CPU sec, 3.240 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 281367, 23, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 218, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1128)
[M::mem_pestat] mean and std.dev: (286.86, 261.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1456)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 334, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 969)
[M::mem_pestat] mean and std.dev: (353.00, 169.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1220)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (485, 664, 1555)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3695)
[M::mem_pestat] mean and std.dev: (786.59, 534.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4765)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 323, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 997)
[M::mem_pestat] mean and std.dev: (334.27, 185.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1264)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680030 reads in 180.463 CPU sec, 6.101 real sec
[M::mem_process_seqs] Processed 679862 reads in 119.142 CPU sec, 4.013 real sec
[M::process] read 680226 sequences (100000155 bp) in 2.229 CPU sec, 2.377 real sec...
sorting block 51, #reads = 1075156 mem = 536878357 peak = 990425088
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 281470, 10, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 247, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1108)
[M::mem_pestat] mean and std.dev: (307.89, 206.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1431)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 333, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 966)
[M::mem_pestat] mean and std.dev: (352.09, 169.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1216)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (125, 1620, 3444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10082)
[M::mem_pestat] mean and std.dev: (1957.10, 2253.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13401)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 272, 729)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1815)
[M::mem_pestat] mean and std.dev: (387.43, 274.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2358)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680254 sequences (100000170 bp) in 2.433 CPU sec, 2.993 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 281178, 11, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 309, 501)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1057)
[M::mem_pestat] mean and std.dev: (348.38, 215.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1335)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 332, 464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 962)
[M::mem_pestat] mean and std.dev: (351.31, 169.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1211)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 540, 1170)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3058)
[M::mem_pestat] mean and std.dev: (864.18, 773.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4002)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 358, 401)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 767)
[M::mem_pestat] mean and std.dev: (313.78, 117.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 950)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 679850 reads in 180.719 CPU sec, 5.834 real sec
[M::mem_process_seqs] Processed 680226 reads in 118.623 CPU sec, 3.787 real sec
sorting block 52, #reads = 1076300 mem = 536880091 peak = 990425088
[M::process] read 680278 sequences (100000268 bp) in 2.132 CPU sec, 2.213 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 280810, 8, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 288, 1227)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3305)
[M::mem_pestat] mean and std.dev: (599.77, 664.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4344)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 327, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 945)
[M::mem_pestat] mean and std.dev: (346.61, 166.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1189)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 288, 495)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1069)
[M::mem_pestat] mean and std.dev: (352.13, 197.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1356)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 53, #reads = 1075794 mem = 536878567 peak = 990425088
[M::process] read 680244 sequences (100000022 bp) in 2.890 CPU sec, 3.288 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 281312, 8, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 384, 720)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1820)
[M::mem_pestat] mean and std.dev: (430.91, 295.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2370)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 329, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 960)
[M::mem_pestat] mean and std.dev: (349.62, 169.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1209)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 267, 413)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 939)
[M::mem_pestat] mean and std.dev: (263.38, 133.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1202)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680254 reads in 178.918 CPU sec, 5.735 real sec
[M::process] read 680526 sequences (100000013 bp) in 1.953 CPU sec, 1.993 real sec...
[M::mem_process_seqs] Processed 680278 reads in 118.711 CPU sec, 3.752 real sec
sorting block 54, #reads = 1075473 mem = 536880994 peak = 990425088
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 280958, 24, 81)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 241, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1035)
[M::mem_pestat] mean and std.dev: (269.27, 141.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1317)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 327, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 951)
[M::mem_pestat] mean and std.dev: (347.64, 167.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1197)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 231, 1663)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4653)
[M::mem_pestat] mean and std.dev: (583.10, 704.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6148)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (301, 388, 517)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 949)
[M::mem_pestat] mean and std.dev: (362.26, 125.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1165)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680258 sequences (100000266 bp) in 2.622 CPU sec, 2.837 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 281758, 9, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (270, 339, 3046)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8598)
[M::mem_pestat] mean and std.dev: (1278.87, 1497.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11374)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 328, 460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 954)
[M::mem_pestat] mean and std.dev: (348.00, 168.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1201)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 435, 620)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1396)
[M::mem_pestat] mean and std.dev: (428.33, 273.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1784)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680108 sequences (100000247 bp) in 1.780 CPU sec, 1.782 real sec...
[M::mem_process_seqs] Processed 680244 reads in 175.700 CPU sec, 5.607 real sec
[M::mem_process_seqs] Processed 680526 reads in 113.937 CPU sec, 3.618 real sec
sorting block 55, #reads = 1076507 mem = 536882279 peak = 990425088
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 281623, 10, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 288, 391)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 819)
[M::mem_pestat] mean and std.dev: (321.32, 187.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1070)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 329, 460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 952)
[M::mem_pestat] mean and std.dev: (348.84, 168.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1198)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (725, 3774, 9719)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 27707)
[M::mem_pestat] mean and std.dev: (4698.10, 4189.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 36701)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 340, 597)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1299)
[M::mem_pestat] mean and std.dev: (381.35, 186.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1650)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680488 sequences (100000197 bp) in 2.789 CPU sec, 2.928 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 281390, 7, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 277, 622)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1526)
[M::mem_pestat] mean and std.dev: (355.52, 267.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1978)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 331, 464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 964)
[M::mem_pestat] mean and std.dev: (350.29, 169.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1214)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (260, 356, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 866)
[M::mem_pestat] mean and std.dev: (335.74, 137.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1068)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680162 sequences (100000020 bp) in 1.861 CPU sec, 1.869 real sec...
[M::mem_process_seqs] Processed 680258 reads in 172.592 CPU sec, 5.479 real sec
[M::mem_process_seqs] Processed 680108 reads in 112.503 CPU sec, 3.556 real sec
sorting block 56, #reads = 1076824 mem = 536878034 peak = 990425088
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 281887, 12, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 246, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1029)
[M::mem_pestat] mean and std.dev: (265.86, 154.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1326)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 329, 464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 968)
[M::mem_pestat] mean and std.dev: (350.09, 170.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1220)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (877, 1114, 2211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4879)
[M::mem_pestat] mean and std.dev: (1265.17, 775.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6213)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (267, 316, 554)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1128)
[M::mem_pestat] mean and std.dev: (338.05, 168.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1415)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680756 sequences (100000044 bp) in 3.055 CPU sec, 3.194 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 281722, 16, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 299, 401)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 769)
[M::mem_pestat] mean and std.dev: (291.79, 104.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 953)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 332, 464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 964)
[M::mem_pestat] mean and std.dev: (351.00, 169.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1214)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (386, 587, 2062)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5414)
[M::mem_pestat] mean and std.dev: (1020.12, 961.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7090)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 301, 383)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (276.28, 122.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 950)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680894 sequences (100000183 bp) in 1.890 CPU sec, 1.891 real sec...
[M::mem_process_seqs] Processed 680488 reads in 177.655 CPU sec, 5.647 real sec
sorting block 57, #reads = 1077754 mem = 536880513 peak = 990425088
[M::mem_process_seqs] Processed 680162 reads in 118.214 CPU sec, 3.738 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 282421, 4, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 293, 519)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1243)
[M::mem_pestat] mean and std.dev: (313.70, 188.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1605)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 327, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 967)
[M::mem_pestat] mean and std.dev: (348.80, 171.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1219)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (278, 367, 662)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1430)
[M::mem_pestat] mean and std.dev: (424.14, 230.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1814)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 58, #reads = 1076110 mem = 536882125 peak = 990425088
[M::process] read 679232 sequences (100000152 bp) in 2.966 CPU sec, 3.181 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 281436, 10, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 302, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 987)
[M::mem_pestat] mean and std.dev: (319.49, 171.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1248)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 326, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 943)
[M::mem_pestat] mean and std.dev: (344.33, 165.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1187)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 1163, 1592)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4476)
[M::mem_pestat] mean and std.dev: (879.90, 620.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5918)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 324, 403)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701)
[M::mem_pestat] mean and std.dev: (302.77, 105.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 850)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 678814 sequences (100000154 bp) in 1.886 CPU sec, 1.890 real sec...
[M::mem_process_seqs] Processed 680756 reads in 179.262 CPU sec, 5.705 real sec
[M::mem_process_seqs] Processed 680894 reads in 118.393 CPU sec, 3.750 real sec
sorting block 59, #reads = 1075527 mem = 536879262 peak = 990425088
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 280543, 9, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (273, 437, 841)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1977)
[M::mem_pestat] mean and std.dev: (587.68, 475.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2545)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 335, 460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 938)
[M::mem_pestat] mean and std.dev: (350.50, 163.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1177)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 254, 405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 833)
[M::mem_pestat] mean and std.dev: (266.66, 104.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1047)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 678990 sequences (100000159 bp) in 2.558 CPU sec, 2.708 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 280469, 8, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 266, 546)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1158)
[M::mem_pestat] mean and std.dev: (350.50, 175.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1464)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 341, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 952)
[M::mem_pestat] mean and std.dev: (355.18, 164.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1195)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 298, 380)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (280.67, 116.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 944)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 679298 sequences (100000045 bp) in 1.701 CPU sec, 1.708 real sec...
[M::mem_process_seqs] Processed 679232 reads in 169.764 CPU sec, 5.415 real sec
[M::mem_process_seqs] Processed 678814 reads in 112.415 CPU sec, 3.563 real sec
sorting block 60, #reads = 1076101 mem = 536879151 peak = 990425088
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 280247, 7, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 285, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 734)
[M::mem_pestat] mean and std.dev: (280.66, 145.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 919)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 340, 464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 948)
[M::mem_pestat] mean and std.dev: (353.92, 164.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1190)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 293, 584)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1312)
[M::mem_pestat] mean and std.dev: (310.29, 151.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1676)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 679664 sequences (100000060 bp) in 2.581 CPU sec, 2.748 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 281323, 7, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 270, 394)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 774)
[M::mem_pestat] mean and std.dev: (275.37, 110.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 964)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 336, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 943)
[M::mem_pestat] mean and std.dev: (351.46, 164.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1184)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 246, 425)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 911)
[M::mem_pestat] mean and std.dev: (275.04, 129.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1154)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680080 sequences (100000076 bp) in 1.852 CPU sec, 1.857 real sec...
[M::mem_process_seqs] Processed 678990 reads in 171.265 CPU sec, 5.450 real sec
[M::mem_process_seqs] Processed 679298 reads in 111.344 CPU sec, 3.523 real sec
sorting block 61, #reads = 1075655 mem = 536880740 peak = 990425088
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 281821, 12, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 317, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1061)
[M::mem_pestat] mean and std.dev: (274.05, 133.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1370)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 334, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 933)
[M::mem_pestat] mean and std.dev: (348.80, 163.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1171)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (4, 66, 4881)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 14635)
[M::mem_pestat] mean and std.dev: (1314.50, 2072.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 19512)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (277, 436, 3859)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11023)
[M::mem_pestat] mean and std.dev: (1562.42, 1638.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14605)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 677256 sequences (100000084 bp) in 2.619 CPU sec, 2.776 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 280971, 7, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 344, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 924)
[M::mem_pestat] mean and std.dev: (339.67, 132.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1152)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 332, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 942)
[M::mem_pestat] mean and std.dev: (348.63, 164.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1184)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (261, 323, 631)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1371)
[M::mem_pestat] mean and std.dev: (339.38, 187.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1741)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 679664 reads in 169.697 CPU sec, 5.410 real sec
[M::process] read 677922 sequences (100000164 bp) in 1.914 CPU sec, 1.922 real sec...
sorting block 62, #reads = 1077227 mem = 536878076 peak = 990425088
[M::mem_process_seqs] Processed 680080 reads in 112.673 CPU sec, 3.561 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 280554, 10, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (323, 433, 769)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1661)
[M::mem_pestat] mean and std.dev: (413.03, 228.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2107)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 356, 482)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 978)
[M::mem_pestat] mean and std.dev: (368.47, 169.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1226)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 1578, 1578)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4436)
[M::mem_pestat] mean and std.dev: (879.38, 706.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5865)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 321, 494)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1086)
[M::mem_pestat] mean and std.dev: (328.08, 136.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1382)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 63, #reads = 1077403 mem = 536878126 peak = 1004511232
[M::process] read 681040 sequences (100000183 bp) in 2.890 CPU sec, 3.035 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 280613, 3, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (108, 280, 481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1227)
[M::mem_pestat] mean and std.dev: (284.21, 185.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1600)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 352, 479)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 977)
[M::mem_pestat] mean and std.dev: (365.09, 169.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1226)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 263, 396)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 726)
[M::mem_pestat] mean and std.dev: (273.94, 96.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 891)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 677256 reads in 169.997 CPU sec, 5.409 real sec
[M::process] read 680662 sequences (100000046 bp) in 1.932 CPU sec, 1.941 real sec...
[M::mem_process_seqs] Processed 677922 reads in 111.740 CPU sec, 3.531 real sec
sorting block 64, #reads = 1076047 mem = 536882995 peak = 1004511232
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 281538, 10, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 210, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 778)
[M::mem_pestat] mean and std.dev: (246.27, 123.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 984)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 330, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 953)
[M::mem_pestat] mean and std.dev: (347.02, 166.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1200)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 384, 759)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1987)
[M::mem_pestat] mean and std.dev: (402.00, 279.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2601)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 245, 531)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1217)
[M::mem_pestat] mean and std.dev: (354.42, 263.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1560)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681206 sequences (100000231 bp) in 2.820 CPU sec, 2.973 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 281352, 9, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 507, 2512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7082)
[M::mem_pestat] mean and std.dev: (996.59, 1008.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9367)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 333, 464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 964)
[M::mem_pestat] mean and std.dev: (350.00, 167.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1214)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 267, 1067)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2867)
[M::mem_pestat] mean and std.dev: (327.45, 273.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3767)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681040 reads in 174.420 CPU sec, 5.549 real sec
[M::process] read 680994 sequences (100000010 bp) in 1.911 CPU sec, 1.914 real sec...
[M::mem_process_seqs] Processed 680662 reads in 114.883 CPU sec, 3.632 real sec
sorting block 65, #reads = 1077849 mem = 536884274 peak = 1004511232
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 281953, 13, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 355, 563)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1369)
[M::mem_pestat] mean and std.dev: (384.31, 259.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1772)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 328, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 947)
[M::mem_pestat] mean and std.dev: (345.61, 165.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1192)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (497, 996, 2082)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5252)
[M::mem_pestat] mean and std.dev: (1407.00, 958.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6837)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 276, 398)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 804)
[M::mem_pestat] mean and std.dev: (251.76, 105.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1007)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681054 sequences (100000104 bp) in 2.869 CPU sec, 3.003 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 281821, 9, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 379, 592)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1380)
[M::mem_pestat] mean and std.dev: (401.52, 320.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1774)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 328, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 944)
[M::mem_pestat] mean and std.dev: (345.06, 164.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1188)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 386, 549)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1289)
[M::mem_pestat] mean and std.dev: (367.65, 206.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1659)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681096 sequences (100000009 bp) in 1.895 CPU sec, 1.899 real sec...
[M::mem_process_seqs] Processed 681206 reads in 176.287 CPU sec, 5.601 real sec
sorting block 66, #reads = 1077026 mem = 536876224 peak = 1004511232
[M::mem_process_seqs] Processed 680994 reads in 115.851 CPU sec, 3.663 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 281747, 14, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 235, 290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 526)
[M::mem_pestat] mean and std.dev: (224.62, 80.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 644)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 330, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 959)
[M::mem_pestat] mean and std.dev: (348.27, 167.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1208)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (446, 773, 3996)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11096)
[M::mem_pestat] mean and std.dev: (1610.43, 1864.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14646)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (267, 299, 481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 909)
[M::mem_pestat] mean and std.dev: (316.15, 108.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1123)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 67, #reads = 1077273 mem = 536877921 peak = 1004511232
[M::process] read 680728 sequences (100000100 bp) in 2.635 CPU sec, 2.788 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 281680, 13, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 347, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1015)
[M::mem_pestat] mean and std.dev: (329.23, 203.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1303)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 330, 460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 956)
[M::mem_pestat] mean and std.dev: (347.26, 166.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1204)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1238, 2575, 3580)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8264)
[M::mem_pestat] mean and std.dev: (2371.23, 1123.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10606)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 282, 424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 772)
[M::mem_pestat] mean and std.dev: (304.45, 103.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 946)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 678828 sequences (100000190 bp) in 1.903 CPU sec, 1.913 real sec...
[M::mem_process_seqs] Processed 681054 reads in 179.871 CPU sec, 5.732 real sec
[M::mem_process_seqs] Processed 681096 reads in 120.795 CPU sec, 3.861 real sec
sorting block 68, #reads = 1076891 mem = 536879243 peak = 1004511232
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 281682, 23, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 235, 605)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1531)
[M::mem_pestat] mean and std.dev: (335.32, 232.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1994)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 331, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 960)
[M::mem_pestat] mean and std.dev: (348.73, 167.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1209)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (444, 756, 1592)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3888)
[M::mem_pestat] mean and std.dev: (1007.78, 896.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5036)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 457, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 972)
[M::mem_pestat] mean and std.dev: (356.46, 142.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1224)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 678974 sequences (100000264 bp) in 2.833 CPU sec, 3.069 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 280972, 16, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 228, 380)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 864)
[M::mem_pestat] mean and std.dev: (277.00, 179.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1106)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 347, 477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 981)
[M::mem_pestat] mean and std.dev: (361.86, 170.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1233)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (39, 385, 1799)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5319)
[M::mem_pestat] mean and std.dev: (648.40, 728.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7079)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 288, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (274.33, 85.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 850)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680406 sequences (100000059 bp) in 1.751 CPU sec, 1.770 real sec...
[M::mem_process_seqs] Processed 680728 reads in 180.986 CPU sec, 5.796 real sec
[M::mem_process_seqs] Processed 678828 reads in 118.296 CPU sec, 3.769 real sec
sorting block 69, #reads = 1077155 mem = 536881794 peak = 1004511232
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 280895, 17, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 353, 492)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1086)
[M::mem_pestat] mean and std.dev: (339.82, 178.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1383)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 345, 473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 971)
[M::mem_pestat] mean and std.dev: (359.04, 167.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1220)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1647, 1647, 2493)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4185)
[M::mem_pestat] mean and std.dev: (1558.47, 874.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5057)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 461, 515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1105)
[M::mem_pestat] mean and std.dev: (380.22, 201.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1400)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680224 sequences (100000134 bp) in 2.760 CPU sec, 2.909 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 281827, 12, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 273, 587)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1445)
[M::mem_pestat] mean and std.dev: (363.87, 313.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1874)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 333, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 965)
[M::mem_pestat] mean and std.dev: (350.70, 167.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1215)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (572, 4570, 4570)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12566)
[M::mem_pestat] mean and std.dev: (2698.58, 1915.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16564)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 291, 534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1178)
[M::mem_pestat] mean and std.dev: (329.23, 149.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1500)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 679566 sequences (100000245 bp) in 1.850 CPU sec, 1.849 real sec...
[M::mem_process_seqs] Processed 678974 reads in 175.806 CPU sec, 5.593 real sec
[M::mem_process_seqs] Processed 680406 reads in 115.913 CPU sec, 3.674 real sec
sorting block 70, #reads = 1076209 mem = 536881131 peak = 1004511232
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 281854, 6, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 176, 230)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 408)
[M::mem_pestat] mean and std.dev: (182.24, 63.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 497)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 333, 464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 962)
[M::mem_pestat] mean and std.dev: (350.72, 167.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1211)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 302, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 655)
[M::mem_pestat] mean and std.dev: (286.37, 105.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 798)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 679444 sequences (100000039 bp) in 3.146 CPU sec, 3.283 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 280865, 21, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 238, 292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 538)
[M::mem_pestat] mean and std.dev: (239.76, 104.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 661)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 339, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 973)
[M::mem_pestat] mean and std.dev: (355.94, 168.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1224)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 465, 831)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2097)
[M::mem_pestat] mean and std.dev: (432.26, 324.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2730)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 358, 695)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1621)
[M::mem_pestat] mean and std.dev: (462.24, 305.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2084)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680204 sequences (100000035 bp) in 1.840 CPU sec, 1.846 real sec...
[M::mem_process_seqs] Processed 680224 reads in 182.616 CPU sec, 5.803 real sec
sorting block 71, #reads = 1076459 mem = 536879701 peak = 1004511232
[M::mem_process_seqs] Processed 679566 reads in 121.862 CPU sec, 3.859 real sec
sorting block 72, #reads = 1076877 mem = 536878911 peak = 1004511232
[M::process] read 680092 sequences (100000231 bp) in 2.968 CPU sec, 3.132 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 281144, 13, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 228, 559)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1299)
[M::mem_pestat] mean and std.dev: (351.61, 237.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1669)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 333, 464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 960)
[M::mem_pestat] mean and std.dev: (350.60, 166.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1208)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (517, 547, 2268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5770)
[M::mem_pestat] mean and std.dev: (1179.85, 1051.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7521)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 356, 635)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1515)
[M::mem_pestat] mean and std.dev: (352.82, 242.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1955)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680204 reads in 103.642 CPU sec, 3.257 real sec
[M::process] read 680524 sequences (100000277 bp) in 2.021 CPU sec, 2.031 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 280853, 9, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 394, 608)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1376)
[M::mem_pestat] mean and std.dev: (352.29, 184.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1760)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 341, 473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 979)
[M::mem_pestat] mean and std.dev: (356.78, 169.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1232)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (272, 426, 1126)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2834)
[M::mem_pestat] mean and std.dev: (684.76, 707.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3688)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 281247, 11, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 382, 1158)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3082)
[M::mem_pestat] mean and std.dev: (525.50, 458.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4044)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 332, 464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 962)
[M::mem_pestat] mean and std.dev: (350.67, 167.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1211)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1546, 1812, 3347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6949)
[M::mem_pestat] mean and std.dev: (2148.18, 1116.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8750)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 296, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 924)
[M::mem_pestat] mean and std.dev: (358.87, 205.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1179)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 679444 reads in 281.119 CPU sec, 8.948 real sec
[M::process] read 680510 sequences (100000108 bp) in 2.007 CPU sec, 2.021 real sec...
[M::mem_process_seqs] Processed 680092 reads in 138.744 CPU sec, 4.412 real sec
sorting block 73, #reads = 1075284 mem = 536876488 peak = 1004511232
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 282224, 9, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 322, 823)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2053)
[M::mem_pestat] mean and std.dev: (564.55, 530.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2687)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 326, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 946)
[M::mem_pestat] mean and std.dev: (344.43, 164.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1191)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 370, 526)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1096)
[M::mem_pestat] mean and std.dev: (385.28, 177.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1381)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 74, #reads = 1075495 mem = 536881512 peak = 1004511232
[M::process] read 680628 sequences (100000070 bp) in 2.793 CPU sec, 2.953 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 281625, 8, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 284, 389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (306.24, 130.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 935)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 327, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 953)
[M::mem_pestat] mean and std.dev: (346.33, 166.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1200)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 329, 627)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1451)
[M::mem_pestat] mean and std.dev: (377.05, 252.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1863)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680786 sequences (100000144 bp) in 1.890 CPU sec, 1.891 real sec...
[M::mem_process_seqs] Processed 680524 reads in 181.090 CPU sec, 5.763 real sec
[M::mem_process_seqs] Processed 680510 reads in 118.165 CPU sec, 3.741 real sec
sorting block 75, #reads = 1075899 mem = 536879187 peak = 1004511232
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 282046, 8, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 233, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 747)
[M::mem_pestat] mean and std.dev: (271.74, 167.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 945)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 324, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 943)
[M::mem_pestat] mean and std.dev: (343.52, 164.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1187)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 353, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1014)
[M::mem_pestat] mean and std.dev: (297.89, 153.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1294)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680626 sequences (100000274 bp) in 2.905 CPU sec, 3.063 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 281706, 15, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 261, 480)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1060)
[M::mem_pestat] mean and std.dev: (309.09, 156.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1350)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 325, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 946)
[M::mem_pestat] mean and std.dev: (344.67, 165.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1191)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (440, 1184, 3203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8729)
[M::mem_pestat] mean and std.dev: (1849.87, 1598.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11492)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 247, 389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 805)
[M::mem_pestat] mean and std.dev: (249.68, 104.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1013)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680468 sequences (100000228 bp) in 1.930 CPU sec, 1.933 real sec...
[M::mem_process_seqs] Processed 680628 reads in 178.871 CPU sec, 5.674 real sec
[M::mem_process_seqs] Processed 680786 reads in 115.530 CPU sec, 3.660 real sec
sorting block 76, #reads = 1075376 mem = 536878878 peak = 1004511232
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 281882, 16, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 294, 395)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 807)
[M::mem_pestat] mean and std.dev: (291.37, 121.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1013)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 328, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 960)
[M::mem_pestat] mean and std.dev: (348.68, 168.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1209)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (28, 375, 1569)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4651)
[M::mem_pestat] mean and std.dev: (566.87, 613.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6192)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 369, 643)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1431)
[M::mem_pestat] mean and std.dev: (407.15, 253.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1825)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680878 sequences (100000125 bp) in 2.853 CPU sec, 3.021 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 282497, 2, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 337, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 913)
[M::mem_pestat] mean and std.dev: (317.13, 143.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1147)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 329, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 960)
[M::mem_pestat] mean and std.dev: (348.89, 168.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1209)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 338, 701)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1785)
[M::mem_pestat] mean and std.dev: (452.70, 320.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2327)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682548 sequences (100000301 bp) in 1.958 CPU sec, 1.959 real sec...
[M::mem_process_seqs] Processed 680626 reads in 176.963 CPU sec, 5.621 real sec
[M::mem_process_seqs] Processed 680468 reads in 116.317 CPU sec, 3.672 real sec
sorting block 77, #reads = 1075664 mem = 536880097 peak = 1004511232
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 281825, 15, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (275, 457, 499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 947)
[M::mem_pestat] mean and std.dev: (411.91, 194.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1188)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 325, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 946)
[M::mem_pestat] mean and std.dev: (344.66, 166.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1191)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (509, 622, 6821)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 19445)
[M::mem_pestat] mean and std.dev: (2860.53, 3525.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 25757)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 300, 789)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1869)
[M::mem_pestat] mean and std.dev: (545.75, 443.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2409)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683876 sequences (100000196 bp) in 2.821 CPU sec, 2.965 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 282526, 14, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 265, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (281.20, 150.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 315, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 943)
[M::mem_pestat] mean and std.dev: (337.54, 166.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1190)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (609, 1281, 4900)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13482)
[M::mem_pestat] mean and std.dev: (2676.07, 2909.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17773)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 398, 605)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1303)
[M::mem_pestat] mean and std.dev: (385.80, 203.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1652)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681492 sequences (100000179 bp) in 1.962 CPU sec, 1.968 real sec...
[M::mem_process_seqs] Processed 680878 reads in 175.234 CPU sec, 5.560 real sec
sorting block 78, #reads = 1075999 mem = 536876569 peak = 1004511232
[M::mem_process_seqs] Processed 682548 reads in 116.970 CPU sec, 3.694 real sec
sorting block 79, #reads = 1076535 mem = 536878473 peak = 1004511232
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 283776, 14, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 310, 553)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1201)
[M::mem_pestat] mean and std.dev: (372.55, 223.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1525)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 314, 460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 984)
[M::mem_pestat] mean and std.dev: (340.68, 173.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1246)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (336, 837, 904)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2040)
[M::mem_pestat] mean and std.dev: (533.00, 362.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2608)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 298, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 833)
[M::mem_pestat] mean and std.dev: (331.29, 152.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1032)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681436 sequences (100000176 bp) in 2.817 CPU sec, 2.934 real sec...
[M::process] read 683178 sequences (100000104 bp) in 1.967 CPU sec, 1.975 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 282995, 13, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 350, 575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1423)
[M::mem_pestat] mean and std.dev: (304.35, 160.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1847)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 336, 481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1023)
[M::mem_pestat] mean and std.dev: (357.36, 177.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1294)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (423, 1009, 2558)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6828)
[M::mem_pestat] mean and std.dev: (1387.08, 1021.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8963)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 418, 578)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1370)
[M::mem_pestat] mean and std.dev: (397.59, 264.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1766)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683876 reads in 186.955 CPU sec, 5.936 real sec
[M::mem_process_seqs] Processed 681492 reads in 123.345 CPU sec, 3.910 real sec
sorting block 80, #reads = 1073436 mem = 536878448 peak = 1004511232
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 282541, 7, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 334, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (283.81, 119.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 946)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 333, 476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1008)
[M::mem_pestat] mean and std.dev: (353.89, 174.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1274)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 296, 553)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1265)
[M::mem_pestat] mean and std.dev: (362.25, 208.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1621)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682748 sequences (100000157 bp) in 2.550 CPU sec, 2.665 real sec...
[M::process] read 683238 sequences (100000293 bp) in 1.913 CPU sec, 1.921 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 283519, 12, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 477, 1269)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3305)
[M::mem_pestat] mean and std.dev: (667.10, 582.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4323)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 317, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 967)
[M::mem_pestat] mean and std.dev: (340.75, 169.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1222)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 241, 1742)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4796)
[M::mem_pestat] mean and std.dev: (989.75, 1206.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6323)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 297, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 714)
[M::mem_pestat] mean and std.dev: (267.30, 95.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 884)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681436 reads in 181.574 CPU sec, 5.768 real sec
sorting block 81, #reads = 1073951 mem = 536878632 peak = 1004511232
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 282941, 17, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 288, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 686)
[M::mem_pestat] mean and std.dev: (285.95, 143.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 320, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 982)
[M::mem_pestat] mean and std.dev: (343.59, 171.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1242)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (374, 780, 1915)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4997)
[M::mem_pestat] mean and std.dev: (937.25, 777.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6538)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 270, 1100)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2852)
[M::mem_pestat] mean and std.dev: (573.35, 542.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3728)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682148 sequences (100000198 bp) in 2.379 CPU sec, 2.384 real sec...
[M::mem_process_seqs] Processed 682748 reads in 99.067 CPU sec, 3.130 real sec
[M::mem_process_seqs] Processed 683178 reads in 252.260 CPU sec, 7.996 real sec
sorting block 82, #reads = 1074681 mem = 536878602 peak = 1004511232
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 283369, 6, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 298, 397)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 811)
[M::mem_pestat] mean and std.dev: (308.60, 171.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1018)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 315, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 962)
[M::mem_pestat] mean and std.dev: (338.61, 169.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1216)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 261, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 631)
[M::mem_pestat] mean and std.dev: (251.21, 92.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 778)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680070 sequences (100000124 bp) in 2.583 CPU sec, 2.720 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 283389, 15, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 492, 882)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2240)
[M::mem_pestat] mean and std.dev: (517.41, 459.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2919)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 323, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 976)
[M::mem_pestat] mean and std.dev: (344.82, 169.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1233)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (18, 23, 496)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1452)
[M::mem_pestat] mean and std.dev: (222.29, 292.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1930)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 362, 515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1061)
[M::mem_pestat] mean and std.dev: (380.16, 186.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1334)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683238 reads in 196.315 CPU sec, 6.224 real sec
[M::process] read 683114 sequences (100000117 bp) in 2.054 CPU sec, 2.087 real sec...
[M::mem_process_seqs] Processed 682148 reads in 116.864 CPU sec, 3.686 real sec
sorting block 83, #reads = 1075019 mem = 536877714 peak = 1004511232
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 282118, 13, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 313, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 593)
[M::mem_pestat] mean and std.dev: (251.14, 87.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 733)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 344, 483)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1011)
[M::mem_pestat] mean and std.dev: (360.87, 173.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1275)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (884, 1882, 2157)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4703)
[M::mem_pestat] mean and std.dev: (1328.00, 681.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5976)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (290, 390, 550)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1070)
[M::mem_pestat] mean and std.dev: (338.41, 111.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1330)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683890 sequences (100000017 bp) in 2.498 CPU sec, 2.642 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 282942, 5, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 318, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1007)
[M::mem_pestat] mean and std.dev: (329.11, 158.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1276)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 317, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 958)
[M::mem_pestat] mean and std.dev: (338.95, 167.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1210)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 302, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 609)
[M::mem_pestat] mean and std.dev: (276.90, 110.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 745)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683062 sequences (100000285 bp) in 1.890 CPU sec, 1.892 real sec...
[M::mem_process_seqs] Processed 680070 reads in 178.382 CPU sec, 5.667 real sec
sorting block 84, #reads = 1073075 mem = 536885235 peak = 1004511232
[M::mem_process_seqs] Processed 683114 reads in 117.513 CPU sec, 3.723 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 283308, 15, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 221, 609)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1477)
[M::mem_pestat] mean and std.dev: (255.31, 156.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1911)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 311, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 951)
[M::mem_pestat] mean and std.dev: (334.61, 166.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1202)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (783, 803, 2544)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6066)
[M::mem_pestat] mean and std.dev: (1643.87, 1436.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7827)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (297, 388, 647)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1347)
[M::mem_pestat] mean and std.dev: (391.38, 204.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1697)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682706 sequences (100000282 bp) in 2.866 CPU sec, 3.010 real sec...
[M::process] read 681412 sequences (100000238 bp) in 1.739 CPU sec, 1.740 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 282987, 8, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 226, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 574)
[M::mem_pestat] mean and std.dev: (211.38, 82.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 711)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 317, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 966)
[M::mem_pestat] mean and std.dev: (339.35, 167.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1221)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 303, 401)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (297.48, 132.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 959)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683890 reads in 180.800 CPU sec, 5.735 real sec
sorting block 85, #reads = 1073821 mem = 536880360 peak = 1004511232
[M::mem_process_seqs] Processed 683062 reads in 114.852 CPU sec, 3.639 real sec
sorting block 86, #reads = 1073315 mem = 536878889 peak = 1018011648
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 282431, 13, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 283, 548)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1230)
[M::mem_pestat] mean and std.dev: (366.93, 194.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1571)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 322, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 975)
[M::mem_pestat] mean and std.dev: (343.62, 169.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1232)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (449, 487, 1014)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2144)
[M::mem_pestat] mean and std.dev: (626.69, 282.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2709)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 305, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 990)
[M::mem_pestat] mean and std.dev: (292.00, 167.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1251)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 679610 sequences (100000167 bp) in 2.234 CPU sec, 2.323 real sec...
[M::process] read 681250 sequences (100000062 bp) in 1.490 CPU sec, 1.494 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 282197, 8, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 320, 781)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2037)
[M::mem_pestat] mean and std.dev: (502.22, 435.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2665)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 329, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 983)
[M::mem_pestat] mean and std.dev: (349.02, 170.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1241)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 385, 464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 964)
[M::mem_pestat] mean and std.dev: (357.70, 158.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1214)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682706 reads in 179.730 CPU sec, 5.729 real sec
[M::mem_process_seqs] Processed 681412 reads in 116.788 CPU sec, 3.715 real sec
sorting block 87, #reads = 1073068 mem = 536882161 peak = 1018011648
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 281603, 13, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 349, 493)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 997)
[M::mem_pestat] mean and std.dev: (348.96, 155.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1249)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 346, 483)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1009)
[M::mem_pestat] mean and std.dev: (362.02, 173.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1272)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (24, 306, 411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1185)
[M::mem_pestat] mean and std.dev: (307.46, 243.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1572)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 427, 539)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1127)
[M::mem_pestat] mean and std.dev: (416.21, 201.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1421)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681842 sequences (100000196 bp) in 2.783 CPU sec, 2.931 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 282362, 10, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 372, 616)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1380)
[M::mem_pestat] mean and std.dev: (401.12, 212.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1762)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 330, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 984)
[M::mem_pestat] mean and std.dev: (350.17, 170.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1242)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (683, 2005, 2556)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6302)
[M::mem_pestat] mean and std.dev: (1472.20, 933.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8175)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 290, 499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1035)
[M::mem_pestat] mean and std.dev: (346.02, 181.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1303)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680100 sequences (100000103 bp) in 1.900 CPU sec, 1.903 real sec...
[M::mem_process_seqs] Processed 679610 reads in 178.742 CPU sec, 5.664 real sec
[M::mem_process_seqs] Processed 681250 reads in 117.467 CPU sec, 3.719 real sec
sorting block 88, #reads = 1072458 mem = 536880345 peak = 1018011648
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 282833, 4, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 342, 583)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1397)
[M::mem_pestat] mean and std.dev: (342.47, 204.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1804)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 326, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 975)
[M::mem_pestat] mean and std.dev: (345.50, 168.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1231)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 306, 518)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1108)
[M::mem_pestat] mean and std.dev: (347.81, 167.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1403)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681050 sequences (100000181 bp) in 2.517 CPU sec, 2.669 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 281761, 13, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 371, 900)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2288)
[M::mem_pestat] mean and std.dev: (694.84, 684.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3434)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 338, 475)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 993)
[M::mem_pestat] mean and std.dev: (355.68, 170.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1252)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (53, 432, 863)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2483)
[M::mem_pestat] mean and std.dev: (559.92, 518.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3293)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 332, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 968)
[M::mem_pestat] mean and std.dev: (324.12, 153.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1216)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680704 sequences (100000099 bp) in 1.870 CPU sec, 1.877 real sec...
[M::mem_process_seqs] Processed 681842 reads in 174.643 CPU sec, 5.542 real sec
sorting block 89, #reads = 1072191 mem = 536876666 peak = 1018011648
[M::mem_process_seqs] Processed 680100 reads in 115.691 CPU sec, 3.666 real sec
sorting block 90, #reads = 1071055 mem = 536879410 peak = 1018011648
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 281861, 4, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 312, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 944)
[M::mem_pestat] mean and std.dev: (340.29, 212.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1197)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 326, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 952)
[M::mem_pestat] mean and std.dev: (344.62, 164.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1199)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 258, 408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 902)
[M::mem_pestat] mean and std.dev: (260.52, 119.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1149)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680290 sequences (100000165 bp) in 2.684 CPU sec, 2.789 real sec...
[M::process] read 678990 sequences (100000259 bp) in 1.890 CPU sec, 1.884 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 282016, 12, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 343, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 901)
[M::mem_pestat] mean and std.dev: (353.66, 176.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1122)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 329, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 965)
[M::mem_pestat] mean and std.dev: (347.71, 166.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1216)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (425, 753, 2884)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7802)
[M::mem_pestat] mean and std.dev: (1341.83, 1468.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10261)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 284, 593)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1425)
[M::mem_pestat] mean and std.dev: (373.62, 268.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1841)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681050 reads in 172.860 CPU sec, 5.472 real sec
[M::mem_process_seqs] Processed 680704 reads in 111.122 CPU sec, 3.522 real sec
sorting block 91, #reads = 1072706 mem = 536877664 peak = 1018011648
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 281705, 18, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 252, 921)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2399)
[M::mem_pestat] mean and std.dev: (436.54, 454.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3138)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 334, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 985)
[M::mem_pestat] mean and std.dev: (352.96, 169.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1242)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (435, 1463, 2752)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7386)
[M::mem_pestat] mean and std.dev: (1889.67, 1507.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9703)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 336, 505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1035)
[M::mem_pestat] mean and std.dev: (332.64, 156.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1300)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681480 sequences (100000008 bp) in 2.458 CPU sec, 2.559 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 281834, 16, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 264, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 607)
[M::mem_pestat] mean and std.dev: (255.32, 82.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 741)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 346, 482)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1002)
[M::mem_pestat] mean and std.dev: (361.87, 170.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1262)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1221, 1382, 5310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13488)
[M::mem_pestat] mean and std.dev: (2376.62, 2052.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17577)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 353, 599)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1455)
[M::mem_pestat] mean and std.dev: (361.63, 216.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1883)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681098 sequences (100000069 bp) in 1.900 CPU sec, 1.899 real sec...
[M::mem_process_seqs] Processed 680290 reads in 172.668 CPU sec, 5.480 real sec
[M::mem_process_seqs] Processed 678990 reads in 113.841 CPU sec, 3.604 real sec
sorting block 92, #reads = 1073222 mem = 536878596 peak = 1018011648
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 282342, 11, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 225, 478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1154)
[M::mem_pestat] mean and std.dev: (312.20, 231.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1492)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 324, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 961)
[M::mem_pestat] mean and std.dev: (343.97, 166.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1212)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (84, 129, 960)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2712)
[M::mem_pestat] mean and std.dev: (310.10, 353.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3588)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 251, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1018)
[M::mem_pestat] mean and std.dev: (326.58, 214.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1302)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 679960 sequences (100000210 bp) in 2.637 CPU sec, 2.737 real sec...
[M::process] read 680804 sequences (100000136 bp) in 1.840 CPU sec, 1.843 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 282110, 12, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 252, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 706)
[M::mem_pestat] mean and std.dev: (243.42, 103.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 895)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 324, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 953)
[M::mem_pestat] mean and std.dev: (343.78, 165.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1201)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (981, 1489, 1859)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3615)
[M::mem_pestat] mean and std.dev: (1403.50, 883.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4939)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 300, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 949)
[M::mem_pestat] mean and std.dev: (304.58, 144.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1200)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681480 reads in 174.486 CPU sec, 5.526 real sec
[M::mem_process_seqs] Processed 681098 reads in 112.510 CPU sec, 3.574 real sec
sorting block 93, #reads = 1071437 mem = 536877145 peak = 1018011648
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 282110, 8, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 307, 600)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1336)
[M::mem_pestat] mean and std.dev: (373.70, 260.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1704)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 336, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 984)
[M::mem_pestat] mean and std.dev: (354.66, 170.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1240)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (285, 396, 576)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1158)
[M::mem_pestat] mean and std.dev: (389.40, 186.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1449)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680842 sequences (100000259 bp) in 2.451 CPU sec, 2.548 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 282158, 16, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 356, 616)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1352)
[M::mem_pestat] mean and std.dev: (493.98, 323.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1789)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 330, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 974)
[M::mem_pestat] mean and std.dev: (350.16, 170.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1228)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 1434, 1732)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4922)
[M::mem_pestat] mean and std.dev: (1006.44, 799.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6517)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 249, 395)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 855)
[M::mem_pestat] mean and std.dev: (286.32, 136.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1085)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681054 sequences (100000063 bp) in 1.870 CPU sec, 1.875 real sec...
[M::mem_process_seqs] Processed 679960 reads in 168.102 CPU sec, 5.332 real sec
sorting block 94, #reads = 1071955 mem = 536881228 peak = 1018011648
[M::mem_process_seqs] Processed 680804 reads in 109.790 CPU sec, 3.473 real sec
sorting block 95, #reads = 1071490 mem = 536878820 peak = 1018011648
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 282333, 11, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 338, 601)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1401)
[M::mem_pestat] mean and std.dev: (402.32, 277.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1801)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 328, 464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 972)
[M::mem_pestat] mean and std.dev: (348.27, 169.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1226)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (715, 1287, 2676)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6598)
[M::mem_pestat] mean and std.dev: (1968.82, 2082.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10299)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 253, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653)
[M::mem_pestat] mean and std.dev: (249.38, 118.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 811)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681400 sequences (100000136 bp) in 2.697 CPU sec, 2.799 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 282058, 17, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 275, 576)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1320)
[M::mem_pestat] mean and std.dev: (313.71, 174.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1692)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 328, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 977)
[M::mem_pestat] mean and std.dev: (348.62, 170.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1233)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (838, 1861, 4985)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13279)
[M::mem_pestat] mean and std.dev: (2725.18, 2566.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17426)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 346, 587)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1381)
[M::mem_pestat] mean and std.dev: (364.57, 216.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1778)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 686750 sequences (100000019 bp) in 1.960 CPU sec, 1.963 real sec...
[M::mem_process_seqs] Processed 680842 reads in 168.340 CPU sec, 5.330 real sec
[M::mem_process_seqs] Processed 681054 reads in 110.434 CPU sec, 3.490 real sec
sorting block 96, #reads = 1072832 mem = 536881047 peak = 1018011648
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 282390, 7, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 324, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 987)
[M::mem_pestat] mean and std.dev: (337.51, 181.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1252)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 328, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 980)
[M::mem_pestat] mean and std.dev: (348.55, 170.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1237)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 425, 498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1112)
[M::mem_pestat] mean and std.dev: (372.26, 218.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1419)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 685174 sequences (100000210 bp) in 2.693 CPU sec, 2.785 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 284226, 6, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 304, 381)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 825)
[M::mem_pestat] mean and std.dev: (273.12, 104.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1047)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 294, 428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 908)
[M::mem_pestat] mean and std.dev: (318.68, 158.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1148)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 235, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 627)
[M::mem_pestat] mean and std.dev: (252.97, 94.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 778)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 684718 sequences (100000199 bp) in 1.980 CPU sec, 1.982 real sec...
[M::mem_process_seqs] Processed 681400 reads in 179.734 CPU sec, 5.699 real sec
[M::mem_process_seqs] Processed 686750 reads in 122.333 CPU sec, 3.869 real sec
sorting block 97, #reads = 1071597 mem = 536879704 peak = 1018011648
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 284868, 11, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 281, 399)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 795)
[M::mem_pestat] mean and std.dev: (314.12, 139.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 993)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 306, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 929)
[M::mem_pestat] mean and std.dev: (327.47, 161.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1174)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (554, 634, 2076)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5120)
[M::mem_pestat] mean and std.dev: (981.00, 792.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6642)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 320, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 887)
[M::mem_pestat] mean and std.dev: (290.91, 136.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1109)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683838 sequences (100000146 bp) in 2.491 CPU sec, 2.582 real sec...
[M::process] read 683896 sequences (100000264 bp) in 1.510 CPU sec, 1.511 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 284310, 17, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 384, 1547)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4189)
[M::mem_pestat] mean and std.dev: (742.58, 860.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5510)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 308, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 919)
[M::mem_pestat] mean and std.dev: (327.39, 159.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1160)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (544, 1343, 2810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7342)
[M::mem_pestat] mean and std.dev: (1502.65, 1141.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9608)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (267, 421, 1124)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2838)
[M::mem_pestat] mean and std.dev: (712.43, 656.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3695)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 685174 reads in 184.399 CPU sec, 5.869 real sec
sorting block 98, #reads = 1068531 mem = 536881820 peak = 1018011648
[M::mem_process_seqs] Processed 684718 reads in 116.853 CPU sec, 3.730 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 283843, 6, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 474, 1040)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2674)
[M::mem_pestat] mean and std.dev: (586.00, 482.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3491)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 312, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 933)
[M::mem_pestat] mean and std.dev: (331.49, 161.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1178)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 254, 499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1049)
[M::mem_pestat] mean and std.dev: (321.19, 173.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1324)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 99, #reads = 1067905 mem = 536876564 peak = 1018011648
[M::process] read 684322 sequences (100000235 bp) in 2.181 CPU sec, 2.279 real sec...
[M::process] read 681892 sequences (100000038 bp) in 1.460 CPU sec, 1.456 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 283639, 13, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 289, 639)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1481)
[M::mem_pestat] mean and std.dev: (352.25, 239.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1902)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 313, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 931)
[M::mem_pestat] mean and std.dev: (332.53, 162.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1175)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (835, 1464, 3882)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9976)
[M::mem_pestat] mean and std.dev: (2513.23, 2437.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13023)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 392, 478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 994)
[M::mem_pestat] mean and std.dev: (366.08, 200.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1252)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683838 reads in 175.701 CPU sec, 5.604 real sec
[M::mem_process_seqs] Processed 683896 reads in 113.034 CPU sec, 3.596 real sec
sorting block 100, #reads = 1070821 mem = 536885033 peak = 1018011648
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 284072, 9, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 294, 423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 943)
[M::mem_pestat] mean and std.dev: (310.07, 182.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1203)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 308, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 917)
[M::mem_pestat] mean and std.dev: (328.07, 160.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1157)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 268, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 639)
[M::mem_pestat] mean and std.dev: (267.77, 96.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 779)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683538 sequences (100000153 bp) in 2.649 CPU sec, 2.774 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 283369, 2, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 333, 601)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1461)
[M::mem_pestat] mean and std.dev: (362.53, 200.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1891)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 327, 460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 964)
[M::mem_pestat] mean and std.dev: (344.99, 166.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1216)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 319, 538)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1298)
[M::mem_pestat] mean and std.dev: (292.14, 179.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1678)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683944 sequences (100000258 bp) in 1.890 CPU sec, 1.897 real sec...
[M::mem_process_seqs] Processed 684322 reads in 171.081 CPU sec, 5.424 real sec
[M::mem_process_seqs] Processed 681892 reads in 107.471 CPU sec, 3.396 real sec
sorting block 101, #reads = 1071008 mem = 536880566 peak = 1018011648
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 283600, 19, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 368, 1026)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2688)
[M::mem_pestat] mean and std.dev: (631.03, 681.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3519)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 314, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 935)
[M::mem_pestat] mean and std.dev: (334.16, 163.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1180)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (316, 840, 2673)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7387)
[M::mem_pestat] mean and std.dev: (1586.42, 1687.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9744)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 355, 404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 786)
[M::mem_pestat] mean and std.dev: (306.19, 124.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 977)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683728 sequences (100000039 bp) in 2.486 CPU sec, 2.576 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 283873, 12, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 252, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 752)
[M::mem_pestat] mean and std.dev: (268.14, 153.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 957)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 310, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 933)
[M::mem_pestat] mean and std.dev: (331.53, 162.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1178)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 384, 3218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9242)
[M::mem_pestat] mean and std.dev: (1608.42, 2507.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12254)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 387, 916)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2302)
[M::mem_pestat] mean and std.dev: (600.19, 497.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2995)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683194 sequences (100000020 bp) in 1.709 CPU sec, 1.711 real sec...
[M::mem_process_seqs] Processed 683538 reads in 165.835 CPU sec, 5.268 real sec
[M::mem_process_seqs] Processed 683944 reads in 107.760 CPU sec, 3.406 real sec
sorting block 102, #reads = 1072405 mem = 536880127 peak = 1018011648
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 283616, 17, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (128, 204, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1055)
[M::mem_pestat] mean and std.dev: (243.81, 138.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1364)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 311, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 931)
[M::mem_pestat] mean and std.dev: (332.21, 162.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1175)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 679, 980)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2530)
[M::mem_pestat] mean and std.dev: (735.00, 663.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3387)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 286, 393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 777)
[M::mem_pestat] mean and std.dev: (284.55, 134.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 969)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681872 sequences (100000211 bp) in 2.672 CPU sec, 2.799 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 283561, 11, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 237, 509)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1117)
[M::mem_pestat] mean and std.dev: (354.92, 234.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1421)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 316, 451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 949)
[M::mem_pestat] mean and std.dev: (337.43, 166.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1198)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (517, 1108, 2452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6322)
[M::mem_pestat] mean and std.dev: (1384.73, 1006.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8257)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 325, 394)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 788)
[M::mem_pestat] mean and std.dev: (288.84, 124.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 985)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 679560 sequences (100000012 bp) in 1.900 CPU sec, 1.902 real sec...
[M::mem_process_seqs] Processed 683728 reads in 170.240 CPU sec, 5.402 real sec
sorting block 103, #reads = 1072484 mem = 536880117 peak = 1018011648
[M::mem_process_seqs] Processed 683194 reads in 109.624 CPU sec, 3.467 real sec
sorting block 104, #reads = 1072816 mem = 536879088 peak = 1018011648
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 283144, 10, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 448, 576)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1278)
[M::mem_pestat] mean and std.dev: (378.64, 178.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1629)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 324, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 960)
[M::mem_pestat] mean and std.dev: (343.40, 167.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1211)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (27, 554, 3278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9780)
[M::mem_pestat] mean and std.dev: (1116.60, 1428.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13031)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (265, 298, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (81, 541)
[M::mem_pestat] mean and std.dev: (281.93, 82.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 633)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682260 sequences (100000267 bp) in 2.501 CPU sec, 2.575 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 282408, 16, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 341, 723)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1699)
[M::mem_pestat] mean and std.dev: (415.98, 305.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2187)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 345, 481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1003)
[M::mem_pestat] mean and std.dev: (361.17, 172.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1264)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 477, 750)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1890)
[M::mem_pestat] mean and std.dev: (470.86, 376.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2460)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 318, 451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 895)
[M::mem_pestat] mean and std.dev: (338.36, 152.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1117)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681714 sequences (100000008 bp) in 1.860 CPU sec, 1.860 real sec...
[M::mem_process_seqs] Processed 681872 reads in 166.562 CPU sec, 5.287 real sec
[M::mem_process_seqs] Processed 679560 reads in 103.378 CPU sec, 3.274 real sec
sorting block 105, #reads = 1072068 mem = 536883129 peak = 1018011648
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 283220, 16, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 324, 706)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1744)
[M::mem_pestat] mean and std.dev: (412.19, 309.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2263)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 326, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 977)
[M::mem_pestat] mean and std.dev: (346.19, 170.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1234)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (299, 357, 800)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1802)
[M::mem_pestat] mean and std.dev: (369.38, 222.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2303)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 300, 524)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1092)
[M::mem_pestat] mean and std.dev: (328.52, 200.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1376)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681180 sequences (100000088 bp) in 2.569 CPU sec, 2.662 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 282740, 15, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 275, 383)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 799)
[M::mem_pestat] mean and std.dev: (272.70, 150.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1007)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 329, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 980)
[M::mem_pestat] mean and std.dev: (349.28, 171.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1237)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (470, 759, 3243)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8789)
[M::mem_pestat] mean and std.dev: (1497.47, 1275.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11562)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 291, 585)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1249)
[M::mem_pestat] mean and std.dev: (351.64, 177.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1581)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681256 sequences (100000029 bp) in 1.830 CPU sec, 1.822 real sec...
[M::mem_process_seqs] Processed 682260 reads in 163.281 CPU sec, 5.183 real sec
[M::mem_process_seqs] Processed 681714 reads in 104.701 CPU sec, 3.307 real sec
sorting block 106, #reads = 1070587 mem = 536878960 peak = 1018011648
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 282241, 13, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 270, 575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1339)
[M::mem_pestat] mean and std.dev: (340.33, 254.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1721)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 331, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 979)
[M::mem_pestat] mean and std.dev: (350.66, 171.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1235)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (917, 917, 2014)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4208)
[M::mem_pestat] mean and std.dev: (1402.31, 971.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5305)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 371, 763)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1843)
[M::mem_pestat] mean and std.dev: (454.02, 444.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2383)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680930 sequences (100000214 bp) in 2.537 CPU sec, 2.643 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 282275, 9, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 299, 417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 891)
[M::mem_pestat] mean and std.dev: (308.87, 145.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1128)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 330, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 981)
[M::mem_pestat] mean and std.dev: (349.67, 170.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1238)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (267, 461, 792)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1842)
[M::mem_pestat] mean and std.dev: (504.72, 288.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2367)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681180 reads in 159.278 CPU sec, 5.057 real sec
[M::process] read 679416 sequences (100000226 bp) in 1.835 CPU sec, 1.841 real sec...
[M::mem_process_seqs] Processed 681256 reads in 104.333 CPU sec, 3.291 real sec
sorting block 107, #reads = 1071630 mem = 536882261 peak = 1018011648
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 282316, 6, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 242, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 973)
[M::mem_pestat] mean and std.dev: (309.35, 176.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1232)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 331, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 985)
[M::mem_pestat] mean and std.dev: (351.12, 171.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1243)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (258, 315, 661)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1467)
[M::mem_pestat] mean and std.dev: (382.61, 234.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1870)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 679508 sequences (100000120 bp) in 2.598 CPU sec, 2.719 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 281354, 10, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 264, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 779)
[M::mem_pestat] mean and std.dev: (257.54, 122.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 985)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 343, 480)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1002)
[M::mem_pestat] mean and std.dev: (361.16, 174.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1263)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (652, 1237, 1512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3232)
[M::mem_pestat] mean and std.dev: (1034.70, 431.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4092)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 273, 494)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1096)
[M::mem_pestat] mean and std.dev: (354.41, 212.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1397)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681332 sequences (100000120 bp) in 1.460 CPU sec, 1.457 real sec...
[M::mem_process_seqs] Processed 680930 reads in 162.485 CPU sec, 5.165 real sec
sorting block 108, #reads = 1071890 mem = 536881733 peak = 1018011648
[M::mem_process_seqs] Processed 679416 reads in 105.197 CPU sec, 3.339 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 282103, 18, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 231, 314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 630)
[M::mem_pestat] mean and std.dev: (221.04, 91.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 788)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 342, 481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1005)
[M::mem_pestat] mean and std.dev: (361.18, 174.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1267)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (253, 623, 4625)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13369)
[M::mem_pestat] mean and std.dev: (1844.50, 1987.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17741)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 385, 916)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2244)
[M::mem_pestat] mean and std.dev: (450.40, 337.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2908)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 109, #reads = 1071179 mem = 536882388 peak = 1018011648
[M::process] read 681106 sequences (100000057 bp) in 2.678 CPU sec, 2.806 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 282375, 14, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 237, 388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 840)
[M::mem_pestat] mean and std.dev: (246.03, 124.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1066)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 327, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 980)
[M::mem_pestat] mean and std.dev: (348.95, 171.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1237)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (918, 2096, 9940)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 27984)
[M::mem_pestat] mean and std.dev: (4531.86, 4219.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 37006)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 293, 563)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1291)
[M::mem_pestat] mean and std.dev: (396.79, 323.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1692)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 679508 reads in 164.529 CPU sec, 5.235 real sec
[M::process] read 680802 sequences (100000187 bp) in 1.729 CPU sec, 1.730 real sec...
[M::mem_process_seqs] Processed 681332 reads in 107.295 CPU sec, 3.390 real sec
sorting block 110, #reads = 1071531 mem = 536885446 peak = 1018011648
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 282696, 20, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 273, 629)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1437)
[M::mem_pestat] mean and std.dev: (296.74, 176.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1841)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 328, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 975)
[M::mem_pestat] mean and std.dev: (349.53, 171.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1230)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (585, 974, 1507)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3351)
[M::mem_pestat] mean and std.dev: (996.84, 658.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4273)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 317, 885)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2143)
[M::mem_pestat] mean and std.dev: (441.24, 308.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2772)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681254 sequences (100000267 bp) in 2.787 CPU sec, 2.905 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 282703, 11, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 365, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 811)
[M::mem_pestat] mean and std.dev: (295.50, 116.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1012)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 333, 474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 996)
[M::mem_pestat] mean and std.dev: (354.59, 174.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1257)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (126, 465, 1464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4140)
[M::mem_pestat] mean and std.dev: (598.36, 586.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5478)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 312, 539)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1123)
[M::mem_pestat] mean and std.dev: (321.45, 157.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1415)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681106 reads in 161.966 CPU sec, 5.155 real sec
[M::process] read 681374 sequences (100000057 bp) in 1.829 CPU sec, 1.849 real sec...
[M::mem_process_seqs] Processed 680802 reads in 105.096 CPU sec, 3.314 real sec
sorting block 111, #reads = 1072429 mem = 536883267 peak = 1018011648
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 282525, 19, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (131, 206, 535)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1343)
[M::mem_pestat] mean and std.dev: (272.08, 195.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1747)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 330, 476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1008)
[M::mem_pestat] mean and std.dev: (354.09, 176.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1274)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (372, 557, 1299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3153)
[M::mem_pestat] mean and std.dev: (782.88, 689.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4080)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 350, 613)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1353)
[M::mem_pestat] mean and std.dev: (430.20, 254.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1723)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681516 sequences (100000126 bp) in 2.975 CPU sec, 3.106 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 282633, 12, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 246, 537)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1307)
[M::mem_pestat] mean and std.dev: (324.93, 265.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1692)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 328, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1000)
[M::mem_pestat] mean and std.dev: (352.83, 177.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1264)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 438, 914)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2438)
[M::mem_pestat] mean and std.dev: (458.73, 413.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3200)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 263, 428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 832)
[M::mem_pestat] mean and std.dev: (291.73, 112.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1034)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681254 reads in 165.708 CPU sec, 5.285 real sec
[M::mem_process_seqs] Processed 681374 reads in 110.075 CPU sec, 3.468 real sec
sorting block 112, #reads = 1072671 mem = 536878582 peak = 1018011648
[M::process] read 684212 sequences (100000026 bp) in 2.007 CPU sec, 2.046 real sec...
sorting block 113, #reads = 1071910 mem = 536879853 peak = 1018011648
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 283263, 10, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 255, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 725)
[M::mem_pestat] mean and std.dev: (286.59, 151.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 905)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 324, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 981)
[M::mem_pestat] mean and std.dev: (348.28, 173.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1239)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (583, 1100, 1205)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2449)
[M::mem_pestat] mean and std.dev: (899.33, 631.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3426)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 327, 677)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1557)
[M::mem_pestat] mean and std.dev: (436.58, 298.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1997)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682870 sequences (100000178 bp) in 2.744 CPU sec, 2.897 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 283590, 16, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 310, 385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 711)
[M::mem_pestat] mean and std.dev: (297.18, 108.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 874)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 682868 sequences (100000240 bp) in 1.820 CPU sec, 1.817 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (196, 308, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 943)
[M::mem_pestat] mean and std.dev: (331.96, 165.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1192)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (369, 971, 1336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3270)
[M::mem_pestat] mean and std.dev: (848.20, 567.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4237)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 274, 610)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1440)
[M::mem_pestat] mean and std.dev: (305.50, 207.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1855)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681516 reads in 182.167 CPU sec, 5.783 real sec
[M::mem_process_seqs] Processed 684212 reads in 120.052 CPU sec, 3.806 real sec
sorting block 114, #reads = 1064467 mem = 536878453 peak = 1018011648
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 283542, 13, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 306, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 960)
[M::mem_pestat] mean and std.dev: (348.92, 188.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1205)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 320, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 950)
[M::mem_pestat] mean and std.dev: (338.54, 164.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1199)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (376, 680, 1968)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5152)
[M::mem_pestat] mean and std.dev: (919.67, 934.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6744)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 406, 675)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1669)
[M::mem_pestat] mean and std.dev: (484.89, 414.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2166)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682254 sequences (100000192 bp) in 2.474 CPU sec, 2.582 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 283626, 8, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 429, 1123)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2903)
[M::mem_pestat] mean and std.dev: (663.18, 560.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3793)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 319, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 953)
[M::mem_pestat] mean and std.dev: (338.71, 165.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1203)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 335, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 749)
[M::mem_pestat] mean and std.dev: (326.91, 126.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 919)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682024 sequences (100000202 bp) in 1.850 CPU sec, 1.847 real sec...
[M::mem_process_seqs] Processed 682870 reads in 157.545 CPU sec, 4.992 real sec
[M::mem_process_seqs] Processed 682868 reads in 100.300 CPU sec, 3.175 real sec
sorting block 115, #reads = 1071749 mem = 536877981 peak = 1018011648
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283530, 13, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 454, 1189)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3163)
[M::mem_pestat] mean and std.dev: (533.49, 407.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4150)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 323, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 953)
[M::mem_pestat] mean and std.dev: (341.53, 165.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1202)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (266, 667, 3230)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9158)
[M::mem_pestat] mean and std.dev: (1394.38, 1505.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12122)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (295, 346, 1059)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2587)
[M::mem_pestat] mean and std.dev: (569.71, 480.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3351)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681814 sequences (100000243 bp) in 2.652 CPU sec, 2.764 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 282898, 6, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 334, 981)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2651)
[M::mem_pestat] mean and std.dev: (461.44, 507.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3486)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 324, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 962)
[M::mem_pestat] mean and std.dev: (342.96, 166.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1214)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 279, 475)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1079)
[M::mem_pestat] mean and std.dev: (355.35, 232.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1381)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682254 reads in 153.661 CPU sec, 4.873 real sec
[M::process] read 679310 sequences (100000124 bp) in 1.900 CPU sec, 1.905 real sec...
[M::mem_process_seqs] Processed 682024 reads in 99.330 CPU sec, 3.127 real sec
sorting block 116, #reads = 1075345 mem = 536878749 peak = 1018011648
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 282861, 15, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 323, 701)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1733)
[M::mem_pestat] mean and std.dev: (428.29, 363.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2249)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 329, 464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 976)
[M::mem_pestat] mean and std.dev: (346.88, 168.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1232)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (573, 4519, 4519)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12411)
[M::mem_pestat] mean and std.dev: (3320.93, 2737.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16357)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 327, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 949)
[M::mem_pestat] mean and std.dev: (311.30, 132.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1199)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680794 sequences (100000011 bp) in 2.400 CPU sec, 2.511 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 282408, 10, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (291, 349, 473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 837)
[M::mem_pestat] mean and std.dev: (335.74, 122.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1019)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 345, 473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 973)
[M::mem_pestat] mean and std.dev: (357.91, 166.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1223)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 1759, 1759)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4965)
[M::mem_pestat] mean and std.dev: (1176.70, 805.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6568)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 311, 419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 771)
[M::mem_pestat] mean and std.dev: (282.45, 87.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 947)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681814 reads in 151.206 CPU sec, 4.812 real sec
sorting block 117, #reads = 1074577 mem = 536879205 peak = 1018011648
[M::mem_process_seqs] Processed 679310 reads in 96.255 CPU sec, 3.027 real sec
[M::process] read 682932 sequences (100000199 bp) in 2.038 CPU sec, 2.090 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 282209, 12, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (115, 218, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 715)
[M::mem_pestat] mean and std.dev: (221.39, 116.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 915)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 334, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 971)
[M::mem_pestat] mean and std.dev: (349.36, 166.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1224)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (31, 828, 2079)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6175)
[M::mem_pestat] mean and std.dev: (849.67, 906.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8223)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 270, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 968)
[M::mem_pestat] mean and std.dev: (278.93, 103.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1219)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 118, #reads = 1074168 mem = 536884576 peak = 1018011648
[M::process] read 683182 sequences (100000209 bp) in 2.567 CPU sec, 2.715 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 283270, 26, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 258, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 708)
[M::mem_pestat] mean and std.dev: (245.40, 106.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 891)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 315, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 931)
[M::mem_pestat] mean and std.dev: (334.19, 161.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1174)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (398, 678, 1431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3497)
[M::mem_pestat] mean and std.dev: (892.54, 787.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4530)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 336, 393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709)
[M::mem_pestat] mean and std.dev: (332.95, 135.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 874)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680794 reads in 158.812 CPU sec, 5.058 real sec
[M::mem_process_seqs] Processed 682932 reads in 103.181 CPU sec, 3.252 real sec
[M::process] read 683320 sequences (100000285 bp) in 2.185 CPU sec, 2.225 real sec...
sorting block 119, #reads = 1074136 mem = 536880413 peak = 1018011648
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283388, 11, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 320, 376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 728)
[M::mem_pestat] mean and std.dev: (277.27, 122.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 904)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 314, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 919)
[M::mem_pestat] mean and std.dev: (332.36, 160.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1158)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (965, 965, 1606)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2888)
[M::mem_pestat] mean and std.dev: (1041.45, 746.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4028)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 327, 394)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 782)
[M::mem_pestat] mean and std.dev: (297.65, 108.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 976)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682744 sequences (100000093 bp) in 2.460 CPU sec, 2.604 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 283986, 6, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 251, 612)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1474)
[M::mem_pestat] mean and std.dev: (401.58, 353.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1905)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 312, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 923)
[M::mem_pestat] mean and std.dev: (331.18, 159.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1164)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 380, 635)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1495)
[M::mem_pestat] mean and std.dev: (370.82, 179.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1925)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683182 reads in 160.960 CPU sec, 5.126 real sec
[M::process] read 682236 sequences (100000176 bp) in 1.759 CPU sec, 1.779 real sec...
sorting block 120, #reads = 1075484 mem = 536882638 peak = 1018011648
[M::process] read 682526 sequences (100000164 bp) in 1.906 CPU sec, 1.907 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 283102, 9, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 390, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 959)
[M::mem_pestat] mean and std.dev: (340.79, 152.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1221)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 319, 451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 943)
[M::mem_pestat] mean and std.dev: (338.67, 163.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1189)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 294, 999)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2531)
[M::mem_pestat] mean and std.dev: (543.00, 423.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3297)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682236 reads in 81.775 CPU sec, 2.790 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 283271, 11, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 226, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 608)
[M::mem_pestat] mean and std.dev: (251.88, 121.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 753)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 316, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 926)
[M::mem_pestat] mean and std.dev: (334.06, 160.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1167)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (73, 97, 539)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1471)
[M::mem_pestat] mean and std.dev: (246.20, 429.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1965)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 420, 663)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1735)
[M::mem_pestat] mean and std.dev: (419.27, 302.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2271)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682744 reads in 172.721 CPU sec, 6.258 real sec
sorting block 121, #reads = 1074408 mem = 536879625 peak = 1018011648
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 283184, 18, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 298, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 628)
[M::mem_pestat] mean and std.dev: (247.33, 86.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 780)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 321, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 949)
[M::mem_pestat] mean and std.dev: (339.58, 164.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1197)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (585, 585, 823)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (109, 1299)
[M::mem_pestat] mean and std.dev: (666.58, 157.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1537)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 314, 667)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1501)
[M::mem_pestat] mean and std.dev: (407.71, 267.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1918)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683320 reads in 363.353 CPU sec, 12.332 real sec
[M::process] read 681124 sequences (100000017 bp) in 3.266 CPU sec, 3.470 real sec...
[M::mem_process_seqs] Processed 682526 reads in 107.822 CPU sec, 3.470 real sec
sorting block 122, #reads = 1074118 mem = 536878953 peak = 1018011648
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 282507, 9, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 375, 627)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1429)
[M::mem_pestat] mean and std.dev: (427.73, 292.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1830)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 332, 464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 968)
[M::mem_pestat] mean and std.dev: (348.03, 166.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1220)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 307, 434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 956)
[M::mem_pestat] mean and std.dev: (301.91, 140.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1217)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681124 reads in 93.659 CPU sec, 3.288 real sec
[M::process] read 679978 sequences (100000163 bp) in 3.189 CPU sec, 3.435 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 282876, 29, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 266, 411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 879)
[M::mem_pestat] mean and std.dev: (286.46, 129.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1113)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 340, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 976)
[M::mem_pestat] mean and std.dev: (354.09, 167.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1229)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1109, 1109, 2360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4862)
[M::mem_pestat] mean and std.dev: (1372.61, 797.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6113)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 286, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 617)
[M::mem_pestat] mean and std.dev: (273.46, 93.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 749)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 123, #reads = 1074734 mem = 536877453 peak = 1018011648
[M::process] read 682616 sequences (100000011 bp) in 2.710 CPU sec, 2.873 real sec...
[M::mem_process_seqs] Processed 679978 reads in 91.063 CPU sec, 3.014 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 282422, 10, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 288, 598)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1430)
[M::mem_pestat] mean and std.dev: (339.55, 196.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1846)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 320, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 937)
[M::mem_pestat] mean and std.dev: (338.33, 163.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1181)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (76, 499, 937)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2659)
[M::mem_pestat] mean and std.dev: (555.30, 482.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3520)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 293, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 837)
[M::mem_pestat] mean and std.dev: (315.89, 148.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1036)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682226 sequences (100000040 bp) in 2.557 CPU sec, 2.740 real sec...
[M::mem_process_seqs] Processed 682616 reads in 90.375 CPU sec, 2.958 real sec
sorting block 124, #reads = 1073251 mem = 536881517 peak = 1018011648
[M::process] read 682052 sequences (100000137 bp) in 2.363 CPU sec, 2.478 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 283117, 12, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 249, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 812)
[M::mem_pestat] mean and std.dev: (277.41, 141.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1031)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 321, 451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 941)
[M::mem_pestat] mean and std.dev: (339.56, 163.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1186)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (956, 2039, 5417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 14339)
[M::mem_pestat] mean and std.dev: (2669.67, 2527.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 18800)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 340, 604)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1370)
[M::mem_pestat] mean and std.dev: (437.28, 315.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1753)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681834 sequences (100000099 bp) in 1.780 CPU sec, 1.785 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 282599, 6, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 254, 397)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 831)
[M::mem_pestat] mean and std.dev: (284.21, 148.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1048)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 321, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 944)
[M::mem_pestat] mean and std.dev: (339.58, 163.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1190)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (260, 333, 391)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653)
[M::mem_pestat] mean and std.dev: (309.56, 100.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 784)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682226 reads in 161.406 CPU sec, 5.070 real sec
[M::mem_process_seqs] Processed 682052 reads in 104.089 CPU sec, 3.264 real sec
sorting block 125, #reads = 1074442 mem = 536881747 peak = 1018011648
[M::process] read 681762 sequences (100000226 bp) in 2.206 CPU sec, 2.273 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 282815, 5, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 251, 789)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2055)
[M::mem_pestat] mean and std.dev: (525.48, 577.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2836)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 324, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 957)
[M::mem_pestat] mean and std.dev: (342.98, 165.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1207)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 254, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1029)
[M::mem_pestat] mean and std.dev: (302.17, 195.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1309)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681640 sequences (100000222 bp) in 2.594 CPU sec, 2.736 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 282582, 23, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 212, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 822)
[M::mem_pestat] mean and std.dev: (254.09, 125.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1049)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 326, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 973)
[M::mem_pestat] mean and std.dev: (346.37, 168.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1228)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (434, 1376, 6948)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 19976)
[M::mem_pestat] mean and std.dev: (2721.04, 2840.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 26490)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 423, 476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 974)
[M::mem_pestat] mean and std.dev: (372.70, 212.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1223)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681834 reads in 162.339 CPU sec, 5.153 real sec
sorting block 126, #reads = 1073785 mem = 536877633 peak = 1018011648
[M::process] read 681936 sequences (100000087 bp) in 1.976 CPU sec, 2.004 real sec...
[M::mem_process_seqs] Processed 681762 reads in 105.524 CPU sec, 3.324 real sec
sorting block 127, #reads = 1073247 mem = 536880237 peak = 1019666432
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 282480, 4, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (246, 395, 1127)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2889)
[M::mem_pestat] mean and std.dev: (592.03, 557.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3770)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 325, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 969)
[M::mem_pestat] mean and std.dev: (344.60, 167.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1223)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 243, 566)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1260)
[M::mem_pestat] mean and std.dev: (329.55, 183.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1607)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681966 sequences (100000199 bp) in 2.733 CPU sec, 2.871 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 282482, 6, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 260, 419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 955)
[M::mem_pestat] mean and std.dev: (293.50, 187.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1223)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 326, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 972)
[M::mem_pestat] mean and std.dev: (345.88, 169.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1227)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 263, 404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 846)
[M::mem_pestat] mean and std.dev: (289.17, 117.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1067)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681746 sequences (100000251 bp) in 1.760 CPU sec, 1.761 real sec...
[M::mem_process_seqs] Processed 681640 reads in 165.622 CPU sec, 5.251 real sec
[M::mem_process_seqs] Processed 681936 reads in 106.574 CPU sec, 3.369 real sec
sorting block 128, #reads = 1072159 mem = 536881102 peak = 1019666432
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 283063, 11, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 319, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 985)
[M::mem_pestat] mean and std.dev: (309.82, 186.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1259)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 326, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 981)
[M::mem_pestat] mean and std.dev: (346.77, 170.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1239)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (9, 138, 622)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1848)
[M::mem_pestat] mean and std.dev: (271.60, 315.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2461)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 237, 388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 814)
[M::mem_pestat] mean and std.dev: (257.41, 136.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1027)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681826 sequences (100000160 bp) in 2.765 CPU sec, 2.950 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 282704, 20, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 242, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 917)
[M::mem_pestat] mean and std.dev: (235.00, 91.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1160)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 324, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 975)
[M::mem_pestat] mean and std.dev: (345.17, 169.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1231)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (728, 993, 1539)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3161)
[M::mem_pestat] mean and std.dev: (1062.00, 408.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3972)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 432, 546)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1160)
[M::mem_pestat] mean and std.dev: (388.63, 208.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1467)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681966 reads in 164.066 CPU sec, 5.202 real sec
[M::process] read 682588 sequences (100000035 bp) in 1.878 CPU sec, 1.876 real sec...
[M::mem_process_seqs] Processed 681746 reads in 106.502 CPU sec, 3.361 real sec
sorting block 129, #reads = 1071257 mem = 536881546 peak = 1019666432
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 282250, 18, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 288, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 980)
[M::mem_pestat] mean and std.dev: (295.53, 120.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1236)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 324, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 981)
[M::mem_pestat] mean and std.dev: (346.51, 170.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1239)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (665, 983, 1648)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3614)
[M::mem_pestat] mean and std.dev: (1073.50, 761.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4597)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (266, 512, 833)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1967)
[M::mem_pestat] mean and std.dev: (528.50, 335.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2534)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683138 sequences (100000043 bp) in 2.529 CPU sec, 2.641 real sec...
[M::process] read 685012 sequences (100000100 bp) in 1.410 CPU sec, 1.411 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 282684, 8, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 333, 1100)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2894)
[M::mem_pestat] mean and std.dev: (630.12, 690.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3791)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 317, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 962)
[M::mem_pestat] mean and std.dev: (341.08, 169.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1215)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 284, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1004)
[M::mem_pestat] mean and std.dev: (311.30, 183.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1275)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681826 reads in 157.620 CPU sec, 5.017 real sec
sorting block 130, #reads = 1071233 mem = 536878196 peak = 1019666432
[M::mem_process_seqs] Processed 682588 reads in 98.651 CPU sec, 3.129 real sec
sorting block 131, #reads = 1070649 mem = 536881244 peak = 1019666432
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 282960, 11, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 246, 424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 928)
[M::mem_pestat] mean and std.dev: (288.29, 161.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1180)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 310, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 943)
[M::mem_pestat] mean and std.dev: (335.37, 167.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1191)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (66, 449, 2482)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7314)
[M::mem_pestat] mean and std.dev: (1207.64, 1560.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9730)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 414, 695)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1619)
[M::mem_pestat] mean and std.dev: (452.27, 321.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2081)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 685910 sequences (100000283 bp) in 2.179 CPU sec, 2.295 real sec...
[M::process] read 684908 sequences (100000026 bp) in 1.460 CPU sec, 1.453 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 283986, 19, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 217, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 772)
[M::mem_pestat] mean and std.dev: (244.26, 108.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 978)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 305, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 935)
[M::mem_pestat] mean and std.dev: (328.85, 164.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1182)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 1627, 2345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6657)
[M::mem_pestat] mean and std.dev: (1322.89, 965.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8813)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 309, 552)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1228)
[M::mem_pestat] mean and std.dev: (378.38, 237.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1566)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683138 reads in 172.292 CPU sec, 5.485 real sec
[M::mem_process_seqs] Processed 685012 reads in 117.773 CPU sec, 3.758 real sec
sorting block 132, #reads = 1065520 mem = 536877811 peak = 1019666432
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 284587, 4, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 307, 482)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 976)
[M::mem_pestat] mean and std.dev: (342.76, 185.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1223)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 304, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 921)
[M::mem_pestat] mean and std.dev: (323.14, 156.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1164)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 323, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 915)
[M::mem_pestat] mean and std.dev: (313.42, 132.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1153)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 686190 sequences (100000170 bp) in 2.956 CPU sec, 3.080 real sec...
[M::process] read 685058 sequences (100000078 bp) in 1.860 CPU sec, 1.860 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 283606, 14, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (306, 459, 663)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1377)
[M::mem_pestat] mean and std.dev: (417.12, 192.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1734)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 308, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 927)
[M::mem_pestat] mean and std.dev: (325.93, 156.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1171)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (288, 752, 1389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3591)
[M::mem_pestat] mean and std.dev: (749.58, 618.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4692)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 342, 481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1091)
[M::mem_pestat] mean and std.dev: (368.90, 232.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1396)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 685910 reads in 181.959 CPU sec, 5.774 real sec
[M::mem_process_seqs] Processed 684908 reads in 118.368 CPU sec, 3.754 real sec
sorting block 133, #reads = 1067308 mem = 536879419 peak = 1019666432
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (16, 284222, 23, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 217, 244)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (22, 392)
[M::mem_pestat] mean and std.dev: (205.44, 47.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 298, 426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 898)
[M::mem_pestat] mean and std.dev: (317.62, 153.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1134)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1458, 2432, 2432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4380)
[M::mem_pestat] mean and std.dev: (1839.71, 1027.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5951)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 212, 542)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1272)
[M::mem_pestat] mean and std.dev: (318.82, 217.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1637)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681958 sequences (100000074 bp) in 2.746 CPU sec, 2.874 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 283953, 12, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 343, 1019)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2615)
[M::mem_pestat] mean and std.dev: (473.80, 416.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3413)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 305, 434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 912)
[M::mem_pestat] mean and std.dev: (324.10, 156.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1151)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 502, 1143)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3103)
[M::mem_pestat] mean and std.dev: (528.82, 494.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4083)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 309, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 948)
[M::mem_pestat] mean and std.dev: (323.04, 176.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1191)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 685024 sequences (100000041 bp) in 1.850 CPU sec, 1.844 real sec...
[M::mem_process_seqs] Processed 686190 reads in 180.043 CPU sec, 5.719 real sec
[M::mem_process_seqs] Processed 685058 reads in 115.210 CPU sec, 3.648 real sec
sorting block 134, #reads = 1066698 mem = 536880376 peak = 1019666432
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 282841, 4, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 365, 623)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1433)
[M::mem_pestat] mean and std.dev: (461.17, 332.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1838)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 333, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 966)
[M::mem_pestat] mean and std.dev: (344.78, 162.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1218)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (271, 376, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 784)
[M::mem_pestat] mean and std.dev: (333.97, 111.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 955)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 684980 sequences (100000083 bp) in 2.527 CPU sec, 2.674 real sec...
[M::process] read 686122 sequences (100000150 bp) in 1.490 CPU sec, 1.490 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 283924, 17, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 372, 1108)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2950)
[M::mem_pestat] mean and std.dev: (526.65, 465.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3871)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 305, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 920)
[M::mem_pestat] mean and std.dev: (325.19, 158.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1162)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (384, 1308, 1708)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4356)
[M::mem_pestat] mean and std.dev: (1043.12, 551.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5680)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 465, 921)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2261)
[M::mem_pestat] mean and std.dev: (579.91, 488.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2931)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681958 reads in 171.814 CPU sec, 5.467 real sec
sorting block 135, #reads = 1069095 mem = 536882321 peak = 1019666432
[M::mem_process_seqs] Processed 685024 reads in 108.801 CPU sec, 3.465 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 283876, 7, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 247, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 999)
[M::mem_pestat] mean and std.dev: (280.67, 133.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1263)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 307, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 929)
[M::mem_pestat] mean and std.dev: (327.03, 159.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1174)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 267, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 920)
[M::mem_pestat] mean and std.dev: (271.06, 110.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1162)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 136, #reads = 1068597 mem = 536879020 peak = 1019666432
[M::process] read 685904 sequences (100000057 bp) in 3.061 CPU sec, 3.207 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 284638, 4, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 205, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 669)
[M::mem_pestat] mean and std.dev: (221.19, 96.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 835)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 297, 427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 901)
[M::mem_pestat] mean and std.dev: (318.58, 155.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1138)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 283, 548)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1246)
[M::mem_pestat] mean and std.dev: (318.89, 158.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1595)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 684670 sequences (100000197 bp) in 1.710 CPU sec, 1.711 real sec...
[M::mem_process_seqs] Processed 684980 reads in 169.095 CPU sec, 5.362 real sec
[M::mem_process_seqs] Processed 686122 reads in 109.502 CPU sec, 3.467 real sec
sorting block 137, #reads = 1072172 mem = 536884571 peak = 1019666432
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 284484, 7, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 255, 476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1154)
[M::mem_pestat] mean and std.dev: (240.56, 125.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1493)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 297, 421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 879)
[M::mem_pestat] mean and std.dev: (315.95, 151.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1108)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 414, 1232)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3212)
[M::mem_pestat] mean and std.dev: (630.58, 589.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4202)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683892 sequences (100000283 bp) in 3.433 CPU sec, 3.584 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 284029, 10, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 247, 548)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1302)
[M::mem_pestat] mean and std.dev: (309.61, 226.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1679)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 303, 429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 897)
[M::mem_pestat] mean and std.dev: (322.12, 154.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1131)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 1149, 2012)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5542)
[M::mem_pestat] mean and std.dev: (1382.80, 1249.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7307)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 313, 620)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1376)
[M::mem_pestat] mean and std.dev: (343.97, 175.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1754)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 685904 reads in 172.798 CPU sec, 5.495 real sec
[M::mem_process_seqs] Processed 684670 reads in 109.061 CPU sec, 3.441 real sec
[M::process] read 681496 sequences (100000155 bp) in 1.970 CPU sec, 2.017 real sec...
sorting block 138, #reads = 1071700 mem = 536878996 peak = 1019666432
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 283837, 19, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 257, 413)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 831)
[M::mem_pestat] mean and std.dev: (269.82, 109.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1040)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 309, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 907)
[M::mem_pestat] mean and std.dev: (326.60, 155.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1143)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (409, 951, 1488)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3646)
[M::mem_pestat] mean and std.dev: (829.26, 600.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4725)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 331, 503)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1161)
[M::mem_pestat] mean and std.dev: (324.22, 162.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1490)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682650 sequences (100000296 bp) in 3.066 CPU sec, 3.221 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 282540, 5, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 355, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 841)
[M::mem_pestat] mean and std.dev: (317.47, 126.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1043)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 327, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 944)
[M::mem_pestat] mean and std.dev: (341.35, 160.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1189)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 329, 531)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1229)
[M::mem_pestat] mean and std.dev: (395.11, 301.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1599)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683892 reads in 170.810 CPU sec, 5.445 real sec
[M::mem_process_seqs] Processed 681496 reads in 109.769 CPU sec, 3.466 real sec
[M::process] read 683384 sequences (100000060 bp) in 2.232 CPU sec, 2.286 real sec...
sorting block 139, #reads = 1072526 mem = 536880546 peak = 1019666432
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 283353, 7, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 206, 531)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1283)
[M::mem_pestat] mean and std.dev: (312.44, 220.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1659)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 317, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 920)
[M::mem_pestat] mean and std.dev: (332.68, 157.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1159)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (258, 384, 653)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1443)
[M::mem_pestat] mean and std.dev: (422.03, 236.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1838)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 140, #reads = 1071099 mem = 536879412 peak = 1019666432
[M::process] read 683070 sequences (100000226 bp) in 2.653 CPU sec, 2.773 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 283148, 10, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 259, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1005)
[M::mem_pestat] mean and std.dev: (282.23, 132.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1278)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 313, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 918)
[M::mem_pestat] mean and std.dev: (330.57, 157.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1157)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (625, 1557, 1716)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3898)
[M::mem_pestat] mean and std.dev: (1197.67, 789.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4989)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 376, 714)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1748)
[M::mem_pestat] mean and std.dev: (442.28, 395.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2265)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682650 reads in 165.400 CPU sec, 5.263 real sec
[M::process] read 682414 sequences (100000272 bp) in 1.988 CPU sec, 2.019 real sec...
[M::mem_process_seqs] Processed 683384 reads in 107.114 CPU sec, 3.371 real sec
sorting block 141, #reads = 1071586 mem = 536881776 peak = 1019666432
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283126, 10, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 281, 763)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1919)
[M::mem_pestat] mean and std.dev: (438.12, 419.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2497)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 314, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 922)
[M::mem_pestat] mean and std.dev: (331.82, 158.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1162)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (115, 759, 762)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2056)
[M::mem_pestat] mean and std.dev: (531.80, 310.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2703)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 268, 479)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1085)
[M::mem_pestat] mean and std.dev: (284.18, 153.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1388)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682892 sequences (100000106 bp) in 2.692 CPU sec, 2.815 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 282655, 12, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 323, 520)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1144)
[M::mem_pestat] mean and std.dev: (412.30, 303.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1626)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 319, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 933)
[M::mem_pestat] mean and std.dev: (336.04, 160.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1176)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (554, 6525, 6525)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 18467)
[M::mem_pestat] mean and std.dev: (3527.75, 3015.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 24438)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 342, 610)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1342)
[M::mem_pestat] mean and std.dev: (430.75, 273.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1708)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682520 sequences (100000121 bp) in 1.370 CPU sec, 1.375 real sec...
[M::mem_process_seqs] Processed 683070 reads in 160.065 CPU sec, 5.094 real sec
[M::mem_process_seqs] Processed 682414 reads in 101.512 CPU sec, 3.214 real sec
sorting block 142, #reads = 1072328 mem = 536876442 peak = 1019666432
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 282727, 9, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 315, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 901)
[M::mem_pestat] mean and std.dev: (295.81, 100.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1123)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 315, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 923)
[M::mem_pestat] mean and std.dev: (333.22, 159.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1163)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 371, 475)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1001)
[M::mem_pestat] mean and std.dev: (335.87, 170.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1264)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682336 sequences (100000034 bp) in 2.331 CPU sec, 2.483 real sec...
[M::process] read 682284 sequences (100000010 bp) in 1.380 CPU sec, 1.378 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 282371, 18, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 298, 400)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 842)
[M::mem_pestat] mean and std.dev: (293.62, 138.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1063)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 319, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 942)
[M::mem_pestat] mean and std.dev: (337.76, 162.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1188)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (123, 123, 2140)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6174)
[M::mem_pestat] mean and std.dev: (773.89, 982.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8191)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 376, 483)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 995)
[M::mem_pestat] mean and std.dev: (355.17, 151.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1251)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682892 reads in 151.040 CPU sec, 4.809 real sec
[M::mem_process_seqs] Processed 682520 reads in 95.173 CPU sec, 3.024 real sec
sorting block 143, #reads = 1073107 mem = 536880129 peak = 1019666432
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281948, 8, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 251, 644)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1596)
[M::mem_pestat] mean and std.dev: (369.18, 316.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2072)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 319, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 934)
[M::mem_pestat] mean and std.dev: (336.66, 161.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1177)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 285, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 730)
[M::mem_pestat] mean and std.dev: (273.32, 100.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 912)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682082 sequences (100000276 bp) in 2.166 CPU sec, 2.289 real sec...
[M::process] read 681968 sequences (100000207 bp) in 1.370 CPU sec, 1.375 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 282213, 6, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 197, 474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1062)
[M::mem_pestat] mean and std.dev: (311.17, 196.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1356)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 318, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 937)
[M::mem_pestat] mean and std.dev: (337.38, 162.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1181)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 322, 390)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 704)
[M::mem_pestat] mean and std.dev: (309.00, 122.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 861)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682336 reads in 147.234 CPU sec, 4.679 real sec
sorting block 144, #reads = 1072769 mem = 536879671 peak = 1019666432
[M::mem_process_seqs] Processed 682284 reads in 92.184 CPU sec, 2.928 real sec
sorting block 145, #reads = 1073208 mem = 536883441 peak = 1019666432
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 282193, 7, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 296, 719)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1735)
[M::mem_pestat] mean and std.dev: (365.31, 230.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2243)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 320, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 946)
[M::mem_pestat] mean and std.dev: (339.34, 163.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1193)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 286, 416)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 886)
[M::mem_pestat] mean and std.dev: (322.43, 188.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1121)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681964 sequences (100000097 bp) in 2.275 CPU sec, 2.396 real sec...
[M::process] read 681718 sequences (100000010 bp) in 1.410 CPU sec, 1.401 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 282643, 9, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 211, 276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 490)
[M::mem_pestat] mean and std.dev: (209.10, 84.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 597)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 321, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 947)
[M::mem_pestat] mean and std.dev: (340.49, 164.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1194)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 361, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 929)
[M::mem_pestat] mean and std.dev: (354.00, 143.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1164)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682082 reads in 145.741 CPU sec, 4.629 real sec
[M::mem_process_seqs] Processed 681968 reads in 92.094 CPU sec, 2.920 real sec
sorting block 146, #reads = 1071898 mem = 536878741 peak = 1019666432
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 282598, 8, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 307, 382)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 730)
[M::mem_pestat] mean and std.dev: (293.83, 119.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 904)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 321, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 956)
[M::mem_pestat] mean and std.dev: (341.69, 166.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1206)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 250, 383)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (271.59, 140.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 950)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683082 sequences (100000180 bp) in 2.214 CPU sec, 2.329 real sec...
[M::process] read 35568 sequences (5190484 bp) in 0.300 CPU sec, 0.307 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 282027, 29, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 260, 479)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1041)
[M::mem_pestat] mean and std.dev: (338.19, 227.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1322)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 324, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 960)
[M::mem_pestat] mean and std.dev: (343.84, 167.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1211)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 763, 2491)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7115)
[M::mem_pestat] mean and std.dev: (727.84, 789.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9427)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 270, 388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 790)
[M::mem_pestat] mean and std.dev: (254.49, 113.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 991)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681964 reads in 143.080 CPU sec, 4.578 real sec
[M::mem_process_seqs] Processed 681718 reads in 89.651 CPU sec, 2.875 real sec
sorting block 147, #reads = 1073012 mem = 536878455 peak = 1019666432
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 282834, 17, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 266, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 800)
[M::mem_pestat] mean and std.dev: (258.95, 125.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1017)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 313, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 947)
[M::mem_pestat] mean and std.dev: (336.55, 167.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1196)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (107, 233, 2023)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5855)
[M::mem_pestat] mean and std.dev: (817.50, 1326.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7771)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 290, 693)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1657)
[M::mem_pestat] mean and std.dev: (368.34, 276.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2139)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (3, 14653, 0, 1)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 300, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 919)
[M::mem_pestat] mean and std.dev: (324.03, 161.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1161)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_process_seqs] Processed 683082 reads in 82.133 CPU sec, 2.668 real sec
[M::mem_process_seqs] Processed 35568 reads in 17.745 CPU sec, 0.574 real sec
sorting block 148, #reads = 1073001 mem = 536881252 peak = 1034162176
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 159412580
overall: 70030106624 mem 22985.168 user 552.676 sys 770.067 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1136_3MV-T1-TDNA-1_A23MHWWLT4_1.L008\tPU:L008\tSM:1136_3MV-T1-TDNA-1_A23MHWWLT4_1\tLB:1136_3MV-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1136_3MV-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1136_3MV-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 770.107 sec; CPU: 23537.852 sec
sorting block 149, #reads = 447370 mem = 224042325 peak = 1034162176
uniq header count 1
merging 150 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31 max 192
algo: util-sort
license: sentieon:util=1
output file size: 8904559167
output reads: 160516587
bam_mem_sort: 150 calls 84.548 user 1.693 sys 87.598 real
bam_write: 150 calls 43.482 user 2.431 sys 59.540 real
execute: 1 calls 32.391 user 2.190 sys 820.630 real
merge_files: 1 calls 32.380 user 2.148 sys 50.034 real
parse_chunk: 2391 calls 101.959 user 25.785 sys 135.396 real
read_chunk: 6449 calls 49.329 user 43.847 sys 713.668 real
sort_block: 1 calls 35.905 user 43.145 sys 692.508 real
write_chunk: 4056 calls 31.963 user 1.837 sys 49.008 real
overall: 3309309952 mem 2000.390 user 91.556 sys 820.652 real
ls: cannot access '*.cram': No such file or directory