cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1136_4GR-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 1710.004 CPU sec, 61.864 real sec
[M::process] read 697294 sequences (100000267 bp) in 1.016 CPU sec, 1.016 real sec...
[M::process] read 693606 sequences (100000270 bp) in 1.127 CPU sec, 1.179 real sec...
[M::process] read 694754 sequences (100000044 bp) in 1.408 CPU sec, 1.442 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 283559, 21, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 453, 895)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2235)
[M::mem_pestat] mean and std.dev: (510.36, 376.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2905)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 246, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (273.93, 140.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 963)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 433, 1734)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4788)
[M::mem_pestat] mean and std.dev: (739.06, 824.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6315)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 337, 1091)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2815)
[M::mem_pestat] mean and std.dev: (577.11, 577.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3677)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697178 sequences (100000127 bp) in 1.332 CPU sec, 1.359 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 283265, 31, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 344, 1152)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3058)
[M::mem_pestat] mean and std.dev: (614.62, 675.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4011)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 258, 381)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 807)
[M::mem_pestat] mean and std.dev: (285.98, 147.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1020)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (567, 1619, 2065)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5061)
[M::mem_pestat] mean and std.dev: (1398.43, 1093.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6559)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (292, 699, 1275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3241)
[M::mem_pestat] mean and std.dev: (689.46, 529.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4224)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 282619, 17, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 438, 664)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1560)
[M::mem_pestat] mean and std.dev: (467.02, 339.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2008)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 262, 384)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 810)
[M::mem_pestat] mean and std.dev: (289.01, 147.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1023)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (52, 432, 779)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2233)
[M::mem_pestat] mean and std.dev: (437.38, 471.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2960)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (262, 787, 2480)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6916)
[M::mem_pestat] mean and std.dev: (1374.38, 1316.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9134)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697294 reads in 255.228 CPU sec, 8.313 real sec
[M::mem_process_seqs] Processed 694754 reads in 191.916 CPU sec, 6.294 real sec
[M::mem_process_seqs] Processed 693606 reads in 213.536 CPU sec, 6.987 real sec
sorting block 0, #reads = 1075957 mem = 536878983 peak = 599855104
[M::process] read 696756 sequences (100000239 bp) in 2.100 CPU sec, 2.242 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 283950, 16, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 569, 2575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7297)
[M::mem_pestat] mean and std.dev: (1166.27, 1440.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9658)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 247, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 775)
[M::mem_pestat] mean and std.dev: (276.69, 142.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 979)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (313, 668, 989)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2341)
[M::mem_pestat] mean and std.dev: (636.47, 372.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3017)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 521, 2394)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6708)
[M::mem_pestat] mean and std.dev: (1139.78, 1208.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8865)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697288 sequences (100000135 bp) in 1.447 CPU sec, 1.470 real sec...
[M::process] read 693450 sequences (100000050 bp) in 1.148 CPU sec, 1.146 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 283730, 21, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 311, 512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1220)
[M::mem_pestat] mean and std.dev: (303.84, 206.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1574)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 247, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 770)
[M::mem_pestat] mean and std.dev: (275.71, 141.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 972)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 332, 1640)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4522)
[M::mem_pestat] mean and std.dev: (507.11, 525.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5963)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 253, 1306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3514)
[M::mem_pestat] mean and std.dev: (592.43, 596.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4618)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697178 reads in 172.444 CPU sec, 5.481 real sec
sorting block 1, #reads = 1075312 mem = 536881187 peak = 873533440
[M::process] read 694828 sequences (100000243 bp) in 1.546 CPU sec, 1.550 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 283723, 31, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 519, 828)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2092)
[M::mem_pestat] mean and std.dev: (476.75, 340.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2724)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 245, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (274.64, 141.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 966)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (266, 473, 727)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1649)
[M::mem_pestat] mean and std.dev: (505.25, 306.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2110)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 234, 416)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 880)
[M::mem_pestat] mean and std.dev: (273.62, 133.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1112)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697288 reads in 90.706 CPU sec, 2.892 real sec
sorting block 2, #reads = 1076580 mem = 536876557 peak = 883265536
[M::mem_process_seqs] Processed 696756 reads in 225.970 CPU sec, 7.219 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 282998, 22, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (284, 576, 1264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3224)
[M::mem_pestat] mean and std.dev: (795.53, 670.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4204)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 262, 388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 822)
[M::mem_pestat] mean and std.dev: (290.85, 149.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1039)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (372, 816, 827)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1737)
[M::mem_pestat] mean and std.dev: (593.21, 382.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2192)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 475, 1999)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5547)
[M::mem_pestat] mean and std.dev: (966.55, 935.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7321)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696782 sequences (100000218 bp) in 2.415 CPU sec, 2.534 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 283498, 30, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 276, 972)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2524)
[M::mem_pestat] mean and std.dev: (546.76, 571.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3300)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 253, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 790)
[M::mem_pestat] mean and std.dev: (282.38, 145.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 998)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 616, 1602)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4426)
[M::mem_pestat] mean and std.dev: (949.07, 1141.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5838)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 385, 768)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1808)
[M::mem_pestat] mean and std.dev: (490.82, 353.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2328)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695824 sequences (100000088 bp) in 1.639 CPU sec, 1.640 real sec...
[M::mem_process_seqs] Processed 693450 reads in 257.740 CPU sec, 8.190 real sec
sorting block 3, #reads = 1077232 mem = 536877925 peak = 883265536
[M::mem_process_seqs] Processed 694828 reads in 110.324 CPU sec, 3.589 real sec
sorting block 4, #reads = 1076746 mem = 536880531 peak = 889749504
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 284035, 20, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 246, 1082)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2942)
[M::mem_pestat] mean and std.dev: (626.48, 729.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3872)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 247, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 767)
[M::mem_pestat] mean and std.dev: (275.87, 142.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 968)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (51, 404, 1466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4296)
[M::mem_pestat] mean and std.dev: (737.32, 1063.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5711)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 428, 986)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2468)
[M::mem_pestat] mean and std.dev: (647.49, 573.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3209)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695814 sequences (100000221 bp) in 2.249 CPU sec, 2.374 real sec...
[M::process] read 694664 sequences (100000288 bp) in 1.359 CPU sec, 1.367 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 283310, 31, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 487, 1719)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4797)
[M::mem_pestat] mean and std.dev: (737.53, 675.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6336)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 251, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 783)
[M::mem_pestat] mean and std.dev: (279.74, 144.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 989)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (583, 975, 1808)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4258)
[M::mem_pestat] mean and std.dev: (1052.21, 761.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5483)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 335, 843)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2107)
[M::mem_pestat] mean and std.dev: (540.16, 448.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2739)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696782 reads in 172.416 CPU sec, 5.570 real sec
[M::mem_process_seqs] Processed 695824 reads in 114.474 CPU sec, 3.737 real sec
sorting block 5, #reads = 1077206 mem = 536877836 peak = 889749504
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 283138, 21, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 385, 611)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1347)
[M::mem_pestat] mean and std.dev: (411.23, 249.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1715)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 249, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 774)
[M::mem_pestat] mean and std.dev: (278.49, 143.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 977)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (538, 979, 1691)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3997)
[M::mem_pestat] mean and std.dev: (1126.00, 936.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5150)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 394, 692)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1660)
[M::mem_pestat] mean and std.dev: (439.29, 301.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2144)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693134 sequences (100000159 bp) in 2.322 CPU sec, 2.459 real sec...
[M::process] read 695470 sequences (100000285 bp) in 1.603 CPU sec, 1.616 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283242, 24, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (331, 615, 1407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3559)
[M::mem_pestat] mean and std.dev: (744.82, 638.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4635)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 252, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 776)
[M::mem_pestat] mean and std.dev: (280.04, 142.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 979)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 544, 1215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3271)
[M::mem_pestat] mean and std.dev: (609.82, 677.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4299)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 272, 1191)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3251)
[M::mem_pestat] mean and std.dev: (506.56, 519.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4281)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695814 reads in 179.840 CPU sec, 5.808 real sec
[M::mem_process_seqs] Processed 694664 reads in 121.671 CPU sec, 3.886 real sec
sorting block 6, #reads = 1076407 mem = 536879486 peak = 889749504
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 282440, 21, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 294, 575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1409)
[M::mem_pestat] mean and std.dev: (318.38, 249.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1826)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 258, 378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 794)
[M::mem_pestat] mean and std.dev: (285.79, 144.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1002)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 532, 1504)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3970)
[M::mem_pestat] mean and std.dev: (719.63, 603.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5203)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (258, 328, 806)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1902)
[M::mem_pestat] mean and std.dev: (398.52, 280.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2450)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693726 sequences (100000016 bp) in 2.528 CPU sec, 2.686 real sec...
[M::process] read 694520 sequences (100000079 bp) in 1.714 CPU sec, 1.714 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 282970, 20, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 472, 903)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2299)
[M::mem_pestat] mean and std.dev: (464.12, 403.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2997)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 759)
[M::mem_pestat] mean and std.dev: (275.32, 139.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 957)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 856, 1801)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4987)
[M::mem_pestat] mean and std.dev: (1000.30, 978.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6580)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (266, 364, 804)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1880)
[M::mem_pestat] mean and std.dev: (560.73, 507.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2590)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 693134 reads in 180.977 CPU sec, 5.753 real sec
sorting block 7, #reads = 1075040 mem = 536878317 peak = 889749504
[M::mem_process_seqs] Processed 695470 reads in 124.066 CPU sec, 3.941 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 282106, 37, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (309, 764, 1234)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3084)
[M::mem_pestat] mean and std.dev: (767.60, 621.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4009)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 256, 376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 790)
[M::mem_pestat] mean and std.dev: (283.98, 144.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 997)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (272, 375, 919)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2213)
[M::mem_pestat] mean and std.dev: (422.90, 280.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2860)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 274, 538)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1126)
[M::mem_pestat] mean and std.dev: (334.18, 186.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1420)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 8, #reads = 1074841 mem = 536878098 peak = 889749504
[M::process] read 694548 sequences (100000162 bp) in 2.741 CPU sec, 2.940 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 282902, 21, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 291, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 901)
[M::mem_pestat] mean and std.dev: (315.79, 152.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1122)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 252, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 770)
[M::mem_pestat] mean and std.dev: (279.00, 141.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 971)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (423, 601, 1538)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3768)
[M::mem_pestat] mean and std.dev: (871.90, 722.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4883)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (290, 333, 598)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1214)
[M::mem_pestat] mean and std.dev: (377.77, 199.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1522)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694480 sequences (100000188 bp) in 1.767 CPU sec, 1.772 real sec...
[M::mem_process_seqs] Processed 693726 reads in 178.213 CPU sec, 5.665 real sec
[M::mem_process_seqs] Processed 694520 reads in 130.058 CPU sec, 4.153 real sec
sorting block 9, #reads = 1074640 mem = 536878866 peak = 889749504
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 283126, 30, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (253, 318, 762)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1780)
[M::mem_pestat] mean and std.dev: (446.77, 395.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2289)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 251, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 759)
[M::mem_pestat] mean and std.dev: (277.37, 139.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 956)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (83, 628, 2465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7229)
[M::mem_pestat] mean and std.dev: (1501.24, 1939.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9611)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (345, 494, 980)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2250)
[M::mem_pestat] mean and std.dev: (629.18, 403.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2885)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 692050 sequences (100000041 bp) in 2.702 CPU sec, 2.882 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 282876, 23, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 285, 1964)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5420)
[M::mem_pestat] mean and std.dev: (816.17, 895.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7148)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 252, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (279.45, 141.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 975)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (13, 349, 726)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2152)
[M::mem_pestat] mean and std.dev: (374.62, 394.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2865)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 252, 724)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1828)
[M::mem_pestat] mean and std.dev: (456.46, 497.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2447)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695174 sequences (100000105 bp) in 1.801 CPU sec, 1.808 real sec...
[M::mem_process_seqs] Processed 694548 reads in 176.506 CPU sec, 5.612 real sec
[M::mem_process_seqs] Processed 694480 reads in 119.806 CPU sec, 3.895 real sec
sorting block 10, #reads = 1075856 mem = 536879640 peak = 889749504
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 281678, 34, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 421, 567)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1303)
[M::mem_pestat] mean and std.dev: (355.66, 206.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1671)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 261, 379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 791)
[M::mem_pestat] mean and std.dev: (286.77, 143.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 997)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (793, 1157, 1415)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2659)
[M::mem_pestat] mean and std.dev: (1042.79, 426.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3281)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 425, 719)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1727)
[M::mem_pestat] mean and std.dev: (511.97, 428.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2231)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695346 sequences (100000090 bp) in 2.589 CPU sec, 2.758 real sec...
[M::process] read 693692 sequences (100000283 bp) in 1.767 CPU sec, 1.776 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 283557, 18, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 285, 607)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1553)
[M::mem_pestat] mean and std.dev: (331.63, 283.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2026)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 250, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (275.90, 138.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (326, 757, 1267)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3149)
[M::mem_pestat] mean and std.dev: (588.13, 435.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4090)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 277, 858)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2202)
[M::mem_pestat] mean and std.dev: (471.58, 487.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2874)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 692050 reads in 181.680 CPU sec, 5.885 real sec
sorting block 11, #reads = 1075401 mem = 536880813 peak = 889749504
[M::mem_process_seqs] Processed 695174 reads in 119.712 CPU sec, 3.918 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 283408, 41, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 326, 559)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1309)
[M::mem_pestat] mean and std.dev: (351.95, 244.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1684)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 248, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (275.52, 139.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 383, 1478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4124)
[M::mem_pestat] mean and std.dev: (804.97, 1075.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5447)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 243, 1122)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3076)
[M::mem_pestat] mean and std.dev: (610.82, 651.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4053)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 12, #reads = 1075720 mem = 536878955 peak = 889749504
[M::process] read 695418 sequences (100000130 bp) in 2.789 CPU sec, 2.966 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 282536, 15, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (302, 677, 997)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2387)
[M::mem_pestat] mean and std.dev: (701.53, 536.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3082)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 255, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 776)
[M::mem_pestat] mean and std.dev: (281.80, 141.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 978)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 458, 1244)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3288)
[M::mem_pestat] mean and std.dev: (610.33, 460.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4310)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 303, 1124)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2974)
[M::mem_pestat] mean and std.dev: (448.53, 360.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3899)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694772 sequences (100000300 bp) in 1.712 CPU sec, 1.719 real sec...
[M::mem_process_seqs] Processed 695346 reads in 182.186 CPU sec, 5.906 real sec
[M::mem_process_seqs] Processed 693692 reads in 121.381 CPU sec, 3.950 real sec
sorting block 13, #reads = 1076047 mem = 536879437 peak = 889749504
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 283354, 26, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 353, 1056)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2756)
[M::mem_pestat] mean and std.dev: (495.00, 441.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3606)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 249, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (276.91, 141.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 962)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 833, 1771)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5023)
[M::mem_pestat] mean and std.dev: (1225.35, 1161.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6649)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 288, 429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 863)
[M::mem_pestat] mean and std.dev: (264.18, 88.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1080)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694164 sequences (100000168 bp) in 2.801 CPU sec, 2.971 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 282718, 28, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 374, 1759)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4801)
[M::mem_pestat] mean and std.dev: (969.56, 1217.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6322)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 251, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (279.02, 141.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 975)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (326, 860, 1462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3734)
[M::mem_pestat] mean and std.dev: (960.92, 865.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4870)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (364, 523, 1764)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4564)
[M::mem_pestat] mean and std.dev: (1168.28, 1088.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5964)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695568 sequences (100000203 bp) in 1.820 CPU sec, 1.813 real sec...
[M::mem_process_seqs] Processed 695418 reads in 182.736 CPU sec, 5.902 real sec
[M::mem_process_seqs] Processed 694772 reads in 121.855 CPU sec, 3.858 real sec
sorting block 14, #reads = 1074977 mem = 536881750 peak = 889749504
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (15, 283196, 29, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 600, 1377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3831)
[M::mem_pestat] mean and std.dev: (695.53, 553.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5058)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 255, 375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 789)
[M::mem_pestat] mean and std.dev: (283.24, 144.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 996)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (479, 954, 1445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3377)
[M::mem_pestat] mean and std.dev: (859.70, 478.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4343)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 264, 907)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2349)
[M::mem_pestat] mean and std.dev: (477.71, 486.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3070)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696434 sequences (100000039 bp) in 2.756 CPU sec, 2.936 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 283552, 25, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (257, 367, 1380)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3626)
[M::mem_pestat] mean and std.dev: (776.21, 759.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4749)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 694514 sequences (100000274 bp) in 1.877 CPU sec, 1.882 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (166, 253, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 781)
[M::mem_pestat] mean and std.dev: (279.89, 142.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 986)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 338, 1766)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4970)
[M::mem_pestat] mean and std.dev: (927.33, 1050.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6572)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (456, 857, 2359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6165)
[M::mem_pestat] mean and std.dev: (1419.12, 1315.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8068)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694164 reads in 182.649 CPU sec, 5.938 real sec
sorting block 15, #reads = 1075323 mem = 536877899 peak = 889749504
[M::mem_process_seqs] Processed 695568 reads in 126.706 CPU sec, 4.042 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 283700, 20, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 387, 481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 953)
[M::mem_pestat] mean and std.dev: (321.50, 122.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1189)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 249, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (276.69, 141.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 976)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (299, 578, 1427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3683)
[M::mem_pestat] mean and std.dev: (910.55, 1059.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5149)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 524, 806)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1914)
[M::mem_pestat] mean and std.dev: (518.33, 404.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2468)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696052 sequences (100000224 bp) in 3.007 CPU sec, 3.191 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 282466, 9, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 339, 592)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1374)
[M::mem_pestat] mean and std.dev: (421.77, 288.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1765)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 259, 379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 799)
[M::mem_pestat] mean and std.dev: (285.63, 145.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1009)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 265, 1219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3275)
[M::mem_pestat] mean and std.dev: (556.50, 557.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4303)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696434 reads in 170.579 CPU sec, 5.421 real sec
sorting block 16, #reads = 1075084 mem = 536877899 peak = 889749504
[M::process] read 695758 sequences (100000104 bp) in 1.990 CPU sec, 2.007 real sec...
[M::mem_process_seqs] Processed 694514 reads in 119.075 CPU sec, 4.011 real sec
sorting block 17, #reads = 1077533 mem = 536885051 peak = 930910208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 283255, 18, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 245, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 545)
[M::mem_pestat] mean and std.dev: (246.10, 81.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 664)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 252, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 783)
[M::mem_pestat] mean and std.dev: (279.58, 143.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 989)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (307, 643, 2195)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5971)
[M::mem_pestat] mean and std.dev: (1112.12, 1306.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7859)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 345, 414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 906)
[M::mem_pestat] mean and std.dev: (293.00, 159.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1152)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695554 sequences (100000136 bp) in 2.753 CPU sec, 2.920 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 283535, 19, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 291, 1250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3342)
[M::mem_pestat] mean and std.dev: (692.35, 845.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4388)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 253, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 790)
[M::mem_pestat] mean and std.dev: (281.53, 144.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 998)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (494, 591, 1553)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3671)
[M::mem_pestat] mean and std.dev: (760.65, 549.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4730)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (303, 445, 919)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2151)
[M::mem_pestat] mean and std.dev: (629.16, 533.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2767)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696048 sequences (100000135 bp) in 1.717 CPU sec, 1.720 real sec...
[M::mem_process_seqs] Processed 696052 reads in 176.039 CPU sec, 5.830 real sec
[M::mem_process_seqs] Processed 695758 reads in 116.386 CPU sec, 3.686 real sec
sorting block 18, #reads = 1077780 mem = 536878938 peak = 930910208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 283491, 27, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (337, 697, 1236)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3034)
[M::mem_pestat] mean and std.dev: (772.00, 535.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3933)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 254, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 788)
[M::mem_pestat] mean and std.dev: (281.45, 144.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 995)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 565, 1876)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5328)
[M::mem_pestat] mean and std.dev: (1004.58, 1178.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7054)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (305, 348, 685)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1445)
[M::mem_pestat] mean and std.dev: (496.17, 352.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1908)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693548 sequences (100000036 bp) in 2.563 CPU sec, 2.695 real sec...
[M::process] read 695644 sequences (100000103 bp) in 1.611 CPU sec, 1.625 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 283543, 36, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 321, 729)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1707)
[M::mem_pestat] mean and std.dev: (292.54, 146.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2196)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 250, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 780)
[M::mem_pestat] mean and std.dev: (278.58, 142.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 985)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 382, 1166)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3218)
[M::mem_pestat] mean and std.dev: (544.03, 713.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4244)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (140, 215, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 827)
[M::mem_pestat] mean and std.dev: (274.69, 175.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1056)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695554 reads in 169.580 CPU sec, 5.392 real sec
[M::mem_process_seqs] Processed 696048 reads in 115.924 CPU sec, 3.683 real sec
sorting block 19, #reads = 1077819 mem = 536877455 peak = 930910208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 282881, 26, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 362, 1303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3503)
[M::mem_pestat] mean and std.dev: (759.61, 891.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4603)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 261, 382)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 806)
[M::mem_pestat] mean and std.dev: (287.82, 146.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1018)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 852, 1589)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4463)
[M::mem_pestat] mean and std.dev: (825.26, 677.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5900)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 369, 733)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1693)
[M::mem_pestat] mean and std.dev: (408.45, 327.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2173)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695540 sequences (100000216 bp) in 2.733 CPU sec, 2.912 real sec...
[M::process] read 695366 sequences (100000279 bp) in 1.459 CPU sec, 1.465 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 283169, 15, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 232, 747)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1955)
[M::mem_pestat] mean and std.dev: (451.68, 443.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2559)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 252, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 781)
[M::mem_pestat] mean and std.dev: (279.59, 142.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 986)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (433, 1201, 1508)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3658)
[M::mem_pestat] mean and std.dev: (915.23, 625.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4733)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (323, 508, 1143)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2783)
[M::mem_pestat] mean and std.dev: (666.09, 539.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3603)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 693548 reads in 172.629 CPU sec, 5.677 real sec
sorting block 20, #reads = 1077794 mem = 536878330 peak = 930910208
[M::mem_process_seqs] Processed 695644 reads in 116.958 CPU sec, 3.731 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 284204, 36, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 305, 678)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1538)
[M::mem_pestat] mean and std.dev: (415.00, 301.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1968)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 253, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 781)
[M::mem_pestat] mean and std.dev: (280.32, 143.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 986)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 2068, 2671)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7561)
[M::mem_pestat] mean and std.dev: (1534.03, 1438.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10006)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (280, 364, 1133)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2839)
[M::mem_pestat] mean and std.dev: (680.00, 620.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3692)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 21, #reads = 1077511 mem = 536879966 peak = 930910208
[M::process] read 695034 sequences (100000184 bp) in 2.523 CPU sec, 2.673 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 283337, 19, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (296, 379, 709)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1535)
[M::mem_pestat] mean and std.dev: (504.03, 353.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1948)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 251, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 778)
[M::mem_pestat] mean and std.dev: (279.11, 142.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 982)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (592, 636, 867)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (42, 1417)
[M::mem_pestat] mean and std.dev: (646.56, 248.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1692)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (276, 417, 2162)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5934)
[M::mem_pestat] mean and std.dev: (1049.62, 1286.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7820)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693030 sequences (100000165 bp) in 1.846 CPU sec, 1.848 real sec...
[M::mem_process_seqs] Processed 695540 reads in 163.751 CPU sec, 5.206 real sec
[M::mem_process_seqs] Processed 695366 reads in 111.235 CPU sec, 3.777 real sec
sorting block 22, #reads = 1077515 mem = 536879974 peak = 930910208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 283293, 11, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 417, 630)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1422)
[M::mem_pestat] mean and std.dev: (439.24, 263.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1818)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 253, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 782)
[M::mem_pestat] mean and std.dev: (280.92, 143.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 987)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (448, 1747, 2254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5866)
[M::mem_pestat] mean and std.dev: (1115.20, 861.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7672)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 567, 1853)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5049)
[M::mem_pestat] mean and std.dev: (973.08, 1128.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6647)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 692494 sequences (100000151 bp) in 2.256 CPU sec, 2.377 real sec...
[M::process] read 694498 sequences (100000291 bp) in 1.455 CPU sec, 1.458 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 282412, 20, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 344, 868)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2194)
[M::mem_pestat] mean and std.dev: (398.45, 399.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2857)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 260, 378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 792)
[M::mem_pestat] mean and std.dev: (285.87, 144.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 999)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 534, 1148)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3038)
[M::mem_pestat] mean and std.dev: (652.68, 622.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3983)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 699, 1660)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4584)
[M::mem_pestat] mean and std.dev: (884.00, 888.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6046)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695034 reads in 160.269 CPU sec, 5.355 real sec
[M::mem_process_seqs] Processed 693030 reads in 101.605 CPU sec, 3.232 real sec
sorting block 23, #reads = 1077345 mem = 536878165 peak = 930910208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 282258, 12, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 673, 4368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12638)
[M::mem_pestat] mean and std.dev: (1888.61, 2376.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16773)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 263, 384)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 808)
[M::mem_pestat] mean and std.dev: (289.41, 146.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1020)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (132, 680, 8926)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 26514)
[M::mem_pestat] mean and std.dev: (3169.75, 3905.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 35308)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (370, 742, 1436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3568)
[M::mem_pestat] mean and std.dev: (949.84, 847.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4634)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694826 sequences (100000154 bp) in 2.410 CPU sec, 2.510 real sec...
[M::process] read 695590 sequences (100000159 bp) in 1.440 CPU sec, 1.441 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 282602, 24, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 384, 752)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1864)
[M::mem_pestat] mean and std.dev: (552.92, 490.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2515)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 252, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 771)
[M::mem_pestat] mean and std.dev: (279.37, 141.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 972)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (304, 1044, 1456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3760)
[M::mem_pestat] mean and std.dev: (1055.43, 922.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4912)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 290, 509)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1107)
[M::mem_pestat] mean and std.dev: (318.93, 136.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1406)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 692494 reads in 160.699 CPU sec, 5.166 real sec
sorting block 24, #reads = 1076478 mem = 536880791 peak = 930910208
[M::mem_process_seqs] Processed 694498 reads in 106.618 CPU sec, 3.386 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 282765, 16, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 406, 941)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2381)
[M::mem_pestat] mean and std.dev: (474.04, 477.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3101)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 251, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 776)
[M::mem_pestat] mean and std.dev: (279.60, 142.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 979)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (403, 601, 2351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6247)
[M::mem_pestat] mean and std.dev: (1263.25, 1376.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8195)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 290, 941)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2355)
[M::mem_pestat] mean and std.dev: (420.95, 346.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3062)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 25, #reads = 1076906 mem = 536880786 peak = 930910208
[M::process] read 694812 sequences (100000094 bp) in 2.490 CPU sec, 2.623 real sec...
[M::process] read 694070 sequences (100000205 bp) in 1.456 CPU sec, 1.457 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 283194, 25, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 537, 1390)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3840)
[M::mem_pestat] mean and std.dev: (587.90, 497.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5065)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 249, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 771)
[M::mem_pestat] mean and std.dev: (277.45, 141.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 973)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (270, 738, 1159)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2937)
[M::mem_pestat] mean and std.dev: (707.91, 573.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3826)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 309, 956)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2530)
[M::mem_pestat] mean and std.dev: (507.67, 462.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3317)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694826 reads in 162.599 CPU sec, 5.175 real sec
[M::mem_process_seqs] Processed 695590 reads in 108.075 CPU sec, 3.435 real sec
sorting block 26, #reads = 1076387 mem = 536881555 peak = 930910208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 282512, 11, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (258, 329, 664)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1476)
[M::mem_pestat] mean and std.dev: (462.79, 326.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1882)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 249, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 766)
[M::mem_pestat] mean and std.dev: (276.81, 140.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 966)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (459, 764, 1970)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4992)
[M::mem_pestat] mean and std.dev: (1230.73, 1028.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6503)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 222, 553)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1233)
[M::mem_pestat] mean and std.dev: (302.00, 208.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1573)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693718 sequences (100000067 bp) in 2.942 CPU sec, 3.105 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 282897, 40, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (261, 435, 729)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1665)
[M::mem_pestat] mean and std.dev: (399.36, 248.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2133)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 254, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 771)
[M::mem_pestat] mean and std.dev: (279.94, 140.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 972)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 840, 1401)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3731)
[M::mem_pestat] mean and std.dev: (806.59, 667.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4896)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 328, 716)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1698)
[M::mem_pestat] mean and std.dev: (334.84, 194.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2189)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695306 sequences (100000210 bp) in 1.837 CPU sec, 1.844 real sec...
[M::mem_process_seqs] Processed 694812 reads in 166.654 CPU sec, 5.291 real sec
[M::mem_process_seqs] Processed 694070 reads in 110.656 CPU sec, 3.771 real sec
sorting block 27, #reads = 1075814 mem = 536879653 peak = 930910208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 282847, 31, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 304, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 968)
[M::mem_pestat] mean and std.dev: (280.90, 169.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1234)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 257, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 784)
[M::mem_pestat] mean and std.dev: (283.21, 143.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 989)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (100, 397, 740)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2020)
[M::mem_pestat] mean and std.dev: (551.90, 564.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2808)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 297, 677)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1697)
[M::mem_pestat] mean and std.dev: (393.92, 290.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2207)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695446 sequences (100000183 bp) in 2.670 CPU sec, 2.812 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 283108, 18, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 482, 1181)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3055)
[M::mem_pestat] mean and std.dev: (591.86, 433.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3992)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 249, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (275.88, 139.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 958)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (418, 1028, 1542)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3790)
[M::mem_pestat] mean and std.dev: (772.27, 699.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4914)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 361, 1663)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4523)
[M::mem_pestat] mean and std.dev: (623.91, 584.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5953)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695020 sequences (100000021 bp) in 1.695 CPU sec, 1.695 real sec...
[M::mem_process_seqs] Processed 693718 reads in 176.043 CPU sec, 5.880 real sec
[M::mem_process_seqs] Processed 695306 reads in 115.321 CPU sec, 3.667 real sec
sorting block 28, #reads = 1077189 mem = 536878827 peak = 930910208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 283384, 28, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 331, 1016)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2610)
[M::mem_pestat] mean and std.dev: (548.75, 509.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3407)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 249, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (276.17, 139.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 958)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (859, 1373, 2359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5359)
[M::mem_pestat] mean and std.dev: (1209.32, 879.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6859)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (280, 432, 1190)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3010)
[M::mem_pestat] mean and std.dev: (632.79, 534.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3920)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695716 sequences (100000105 bp) in 3.013 CPU sec, 3.167 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 282996, 28, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 311, 1043)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2753)
[M::mem_pestat] mean and std.dev: (589.97, 544.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3608)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 249, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (276.34, 139.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 958)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (287, 451, 881)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2069)
[M::mem_pestat] mean and std.dev: (526.27, 395.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2663)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 271, 954)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2506)
[M::mem_pestat] mean and std.dev: (502.27, 463.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3282)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696004 sequences (100000127 bp) in 1.785 CPU sec, 1.788 real sec...
[M::mem_process_seqs] Processed 695446 reads in 171.677 CPU sec, 5.460 real sec
sorting block 29, #reads = 1074417 mem = 536877680 peak = 930910208
[M::mem_process_seqs] Processed 695020 reads in 117.796 CPU sec, 4.014 real sec
sorting block 30, #reads = 1076122 mem = 536882053 peak = 930910208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 282886, 18, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 315, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 918)
[M::mem_pestat] mean and std.dev: (277.93, 149.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1155)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (276.45, 141.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 965)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (319, 717, 2931)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8155)
[M::mem_pestat] mean and std.dev: (1283.22, 1262.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10767)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 334, 942)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2372)
[M::mem_pestat] mean and std.dev: (474.48, 390.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3087)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695974 sequences (100000260 bp) in 2.927 CPU sec, 3.072 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 283507, 21, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 338, 1204)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3284)
[M::mem_pestat] mean and std.dev: (548.00, 606.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4324)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 768)
[M::mem_pestat] mean and std.dev: (276.79, 141.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 969)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (382, 1085, 2246)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5974)
[M::mem_pestat] mean and std.dev: (1180.80, 1077.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7838)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 484, 1203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3095)
[M::mem_pestat] mean and std.dev: (481.08, 490.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4041)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697738 sequences (100000237 bp) in 1.825 CPU sec, 1.840 real sec...
[M::mem_process_seqs] Processed 695716 reads in 180.554 CPU sec, 6.017 real sec
[M::mem_process_seqs] Processed 696004 reads in 118.360 CPU sec, 3.755 real sec
sorting block 31, #reads = 1075276 mem = 536879299 peak = 930910208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 283356, 22, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 410, 854)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2184)
[M::mem_pestat] mean and std.dev: (436.57, 304.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2849)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 762)
[M::mem_pestat] mean and std.dev: (275.69, 141.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 961)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (365, 499, 634)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1172)
[M::mem_pestat] mean and std.dev: (450.45, 180.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1441)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (262, 508, 964)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2368)
[M::mem_pestat] mean and std.dev: (557.58, 413.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3070)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697156 sequences (100000257 bp) in 2.972 CPU sec, 3.132 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 283607, 18, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (281, 558, 873)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2057)
[M::mem_pestat] mean and std.dev: (597.25, 408.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2649)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 246, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (271.69, 137.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 947)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 387, 1603)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4307)
[M::mem_pestat] mean and std.dev: (626.12, 583.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5659)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (264, 452, 1248)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3216)
[M::mem_pestat] mean and std.dev: (705.58, 594.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4200)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697016 sequences (100000232 bp) in 1.874 CPU sec, 1.884 real sec...
[M::mem_process_seqs] Processed 695974 reads in 182.592 CPU sec, 5.851 real sec
[M::mem_process_seqs] Processed 697738 reads in 122.008 CPU sec, 3.862 real sec
sorting block 32, #reads = 1075061 mem = 536885035 peak = 930910208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 283789, 27, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (339, 423, 861)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1905)
[M::mem_pestat] mean and std.dev: (539.29, 423.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2427)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 248, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (273.72, 138.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 959)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (412, 634, 1278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3010)
[M::mem_pestat] mean and std.dev: (642.04, 457.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3876)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (297, 631, 1106)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2724)
[M::mem_pestat] mean and std.dev: (659.49, 481.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3533)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695666 sequences (100000175 bp) in 2.857 CPU sec, 3.019 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 283743, 24, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (385, 671, 1368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3334)
[M::mem_pestat] mean and std.dev: (882.82, 753.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4317)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 248, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (274.06, 138.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 960)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (359, 1119, 4311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12215)
[M::mem_pestat] mean and std.dev: (2023.17, 2288.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16167)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 442, 628)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1464)
[M::mem_pestat] mean and std.dev: (443.85, 292.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1882)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695290 sequences (100000202 bp) in 1.602 CPU sec, 1.609 real sec...
[M::mem_process_seqs] Processed 697156 reads in 175.655 CPU sec, 5.600 real sec
sorting block 33, #reads = 1074646 mem = 536879918 peak = 930910208
[M::mem_process_seqs] Processed 697016 reads in 126.650 CPU sec, 4.048 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 284156, 28, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 495, 755)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1723)
[M::mem_pestat] mean and std.dev: (482.25, 259.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2207)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 253, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 772)
[M::mem_pestat] mean and std.dev: (277.77, 139.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 974)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 396, 829)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2219)
[M::mem_pestat] mean and std.dev: (474.57, 339.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2914)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (568, 982, 1595)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3649)
[M::mem_pestat] mean and std.dev: (1136.47, 782.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4676)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 34, #reads = 1076098 mem = 536881357 peak = 945381376
[M::process] read 692528 sequences (100000249 bp) in 3.028 CPU sec, 3.184 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 282852, 20, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 307, 704)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1768)
[M::mem_pestat] mean and std.dev: (356.03, 311.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2300)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 255, 376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 794)
[M::mem_pestat] mean and std.dev: (282.47, 144.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1003)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (124, 447, 1199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3349)
[M::mem_pestat] mean and std.dev: (738.40, 855.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4424)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (271, 584, 1140)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2878)
[M::mem_pestat] mean and std.dev: (737.21, 694.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3747)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696546 sequences (100000075 bp) in 1.700 CPU sec, 1.709 real sec...
[M::mem_process_seqs] Processed 695666 reads in 171.584 CPU sec, 5.453 real sec
[M::mem_process_seqs] Processed 695290 reads in 117.779 CPU sec, 3.732 real sec
sorting block 35, #reads = 1076438 mem = 536877564 peak = 945381376
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 282902, 23, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 263, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 933)
[M::mem_pestat] mean and std.dev: (250.77, 102.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1178)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 267, 388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 818)
[M::mem_pestat] mean and std.dev: (292.22, 147.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1033)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (561, 755, 1035)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1983)
[M::mem_pestat] mean and std.dev: (780.00, 335.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2457)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (291, 550, 1801)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4821)
[M::mem_pestat] mean and std.dev: (876.83, 818.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6331)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696220 sequences (100000179 bp) in 2.952 CPU sec, 3.106 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283912, 20, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 335, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 936)
[M::mem_pestat] mean and std.dev: (313.36, 161.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1186)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 250, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 770)
[M::mem_pestat] mean and std.dev: (276.70, 140.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 972)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 964, 1221)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3207)
[M::mem_pestat] mean and std.dev: (637.41, 473.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4200)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 285, 951)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2493)
[M::mem_pestat] mean and std.dev: (418.77, 354.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3264)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695994 sequences (100000242 bp) in 1.654 CPU sec, 1.662 real sec...
[M::mem_process_seqs] Processed 692528 reads in 173.756 CPU sec, 5.824 real sec
[M::mem_process_seqs] Processed 696546 reads in 116.077 CPU sec, 3.679 real sec
sorting block 36, #reads = 1075951 mem = 536878272 peak = 945381376
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 283589, 34, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 1055, 2111)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5985)
[M::mem_pestat] mean and std.dev: (1401.45, 1549.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7922)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 249, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 776)
[M::mem_pestat] mean and std.dev: (277.33, 141.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 980)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (683, 1150, 1643)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3563)
[M::mem_pestat] mean and std.dev: (1196.38, 832.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4527)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (383, 556, 1305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3149)
[M::mem_pestat] mean and std.dev: (829.64, 665.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4071)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695856 sequences (100000027 bp) in 2.678 CPU sec, 2.808 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 283325, 22, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 385, 719)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1767)
[M::mem_pestat] mean and std.dev: (405.35, 268.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2291)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 250, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 774)
[M::mem_pestat] mean and std.dev: (277.79, 141.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 977)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (327, 717, 2220)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6006)
[M::mem_pestat] mean and std.dev: (1282.00, 1266.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7899)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 410, 1318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3470)
[M::mem_pestat] mean and std.dev: (722.48, 655.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4546)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695362 sequences (100000250 bp) in 1.727 CPU sec, 1.729 real sec...
[M::mem_process_seqs] Processed 696220 reads in 169.472 CPU sec, 5.412 real sec
sorting block 37, #reads = 1077718 mem = 536880942 peak = 945381376
[M::mem_process_seqs] Processed 695994 reads in 115.580 CPU sec, 3.733 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 283698, 38, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (258, 379, 635)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1389)
[M::mem_pestat] mean and std.dev: (359.28, 156.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1766)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 251, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 771)
[M::mem_pestat] mean and std.dev: (277.82, 141.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 973)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (261, 495, 1032)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2574)
[M::mem_pestat] mean and std.dev: (536.26, 455.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3345)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (288, 344, 574)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1146)
[M::mem_pestat] mean and std.dev: (371.83, 205.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1432)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 38, #reads = 1076379 mem = 536885891 peak = 945381376
[M::process] read 695376 sequences (100000111 bp) in 2.756 CPU sec, 2.893 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 282881, 24, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 329, 1879)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5231)
[M::mem_pestat] mean and std.dev: (791.12, 946.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6907)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 251, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 775)
[M::mem_pestat] mean and std.dev: (278.89, 141.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 978)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (361, 720, 1326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3256)
[M::mem_pestat] mean and std.dev: (637.95, 492.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4221)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 258, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 999)
[M::mem_pestat] mean and std.dev: (307.48, 165.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1269)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 692494 sequences (100000288 bp) in 1.679 CPU sec, 1.686 real sec...
[M::mem_process_seqs] Processed 695856 reads in 175.318 CPU sec, 5.633 real sec
[M::mem_process_seqs] Processed 695362 reads in 115.571 CPU sec, 3.664 real sec
sorting block 39, #reads = 1076185 mem = 536879327 peak = 945381376
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 282853, 14, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 392, 778)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1852)
[M::mem_pestat] mean and std.dev: (430.91, 308.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2389)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 252, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 782)
[M::mem_pestat] mean and std.dev: (280.44, 143.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 987)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 264, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1110)
[M::mem_pestat] mean and std.dev: (254.17, 163.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1434)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 357, 775)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1951)
[M::mem_pestat] mean and std.dev: (407.90, 281.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2539)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693902 sequences (100000065 bp) in 2.777 CPU sec, 2.929 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 282649, 25, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 334, 1062)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2854)
[M::mem_pestat] mean and std.dev: (550.83, 458.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3750)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 265, 384)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 806)
[M::mem_pestat] mean and std.dev: (289.70, 145.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1017)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (120, 384, 1686)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4818)
[M::mem_pestat] mean and std.dev: (585.50, 640.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6384)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 520, 832)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2040)
[M::mem_pestat] mean and std.dev: (450.32, 309.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2644)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695014 sequences (100000083 bp) in 1.590 CPU sec, 1.607 real sec...
[M::mem_process_seqs] Processed 695376 reads in 168.798 CPU sec, 5.359 real sec
[M::mem_process_seqs] Processed 692494 reads in 112.972 CPU sec, 3.587 real sec
sorting block 40, #reads = 1075374 mem = 536878986 peak = 945381376
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 282655, 20, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 394, 1601)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4475)
[M::mem_pestat] mean and std.dev: (862.61, 1046.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5912)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 258, 377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 791)
[M::mem_pestat] mean and std.dev: (284.47, 143.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 998)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (577, 1401, 1401)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3049)
[M::mem_pestat] mean and std.dev: (950.50, 597.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3873)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 402, 1160)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3008)
[M::mem_pestat] mean and std.dev: (724.27, 670.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3932)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694918 sequences (100000158 bp) in 2.787 CPU sec, 2.930 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (18, 282720, 33, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 204, 675)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1683)
[M::mem_pestat] mean and std.dev: (393.67, 330.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2187)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 253, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 776)
[M::mem_pestat] mean and std.dev: (279.92, 142.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 979)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (448, 803, 2350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6154)
[M::mem_pestat] mean and std.dev: (1200.44, 1054.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8056)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 425, 822)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1990)
[M::mem_pestat] mean and std.dev: (392.97, 263.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2574)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694676 sequences (100000153 bp) in 1.656 CPU sec, 1.659 real sec...
[M::mem_process_seqs] Processed 693902 reads in 171.107 CPU sec, 5.703 real sec
[M::mem_process_seqs] Processed 695014 reads in 112.629 CPU sec, 3.572 real sec
sorting block 41, #reads = 1073187 mem = 536881198 peak = 945381376
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 283420, 22, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (336, 509, 1380)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3468)
[M::mem_pestat] mean and std.dev: (815.94, 724.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4512)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 252, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (279.37, 142.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 975)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 1349, 2827)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8163)
[M::mem_pestat] mean and std.dev: (1764.18, 2078.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10831)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 339, 1091)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2803)
[M::mem_pestat] mean and std.dev: (666.16, 612.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3659)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694858 sequences (100000210 bp) in 2.789 CPU sec, 2.922 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 283075, 36, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (268, 439, 1363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3553)
[M::mem_pestat] mean and std.dev: (750.39, 727.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4648)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 251, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 770)
[M::mem_pestat] mean and std.dev: (278.96, 141.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 971)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 536, 1572)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4330)
[M::mem_pestat] mean and std.dev: (945.63, 996.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5709)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 435, 1425)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3833)
[M::mem_pestat] mean and std.dev: (715.95, 582.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5037)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695412 sequences (100000006 bp) in 1.890 CPU sec, 1.884 real sec...
[M::mem_process_seqs] Processed 694918 reads in 166.705 CPU sec, 5.286 real sec
sorting block 42, #reads = 1075872 mem = 536876565 peak = 945381376
[M::mem_process_seqs] Processed 694676 reads in 119.469 CPU sec, 3.787 real sec
sorting block 43, #reads = 1076762 mem = 536878010 peak = 945381376
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 282356, 22, 19)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 334, 769)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1841)
[M::mem_pestat] mean and std.dev: (411.88, 303.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2377)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 250, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (276.73, 139.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 962)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (281, 656, 2573)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7157)
[M::mem_pestat] mean and std.dev: (1195.25, 1122.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9449)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 291, 479)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1153)
[M::mem_pestat] mean and std.dev: (329.00, 220.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1490)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695442 sequences (100000085 bp) in 2.660 CPU sec, 2.778 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 283001, 19, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (280, 337, 580)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1180)
[M::mem_pestat] mean and std.dev: (395.00, 196.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1480)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (275.00, 139.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 953)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (378, 490, 1221)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2907)
[M::mem_pestat] mean and std.dev: (871.84, 710.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3750)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 332, 2346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6660)
[M::mem_pestat] mean and std.dev: (1041.80, 1208.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8817)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695592 sequences (100000296 bp) in 1.810 CPU sec, 1.810 real sec...
[M::mem_process_seqs] Processed 694858 reads in 166.388 CPU sec, 5.293 real sec
[M::mem_process_seqs] Processed 695412 reads in 123.447 CPU sec, 3.930 real sec
sorting block 44, #reads = 1076617 mem = 536881946 peak = 945381376
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 283574, 30, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 330, 2448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6900)
[M::mem_pestat] mean and std.dev: (1320.00, 1851.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9126)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 759)
[M::mem_pestat] mean and std.dev: (275.67, 139.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 957)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 280, 1512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4230)
[M::mem_pestat] mean and std.dev: (715.30, 832.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5589)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 286, 493)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1055)
[M::mem_pestat] mean and std.dev: (290.25, 148.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1336)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695334 sequences (100000172 bp) in 2.855 CPU sec, 2.990 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 282757, 29, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 254, 672)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1718)
[M::mem_pestat] mean and std.dev: (296.36, 267.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2241)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (274.88, 138.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 953)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 805, 1094)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2798)
[M::mem_pestat] mean and std.dev: (782.93, 650.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3650)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 639, 1087)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2813)
[M::mem_pestat] mean and std.dev: (696.00, 513.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3676)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695442 reads in 165.229 CPU sec, 5.255 real sec
[M::process] read 695592 sequences (100000269 bp) in 2.138 CPU sec, 2.181 real sec...
[M::mem_process_seqs] Processed 695592 reads in 116.559 CPU sec, 3.693 real sec
sorting block 45, #reads = 1076287 mem = 536879153 peak = 945381376
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 282924, 21, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 239, 647)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1543)
[M::mem_pestat] mean and std.dev: (356.19, 336.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1991)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 249, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (275.77, 139.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (287, 534, 3566)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10124)
[M::mem_pestat] mean and std.dev: (1709.29, 2270.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13403)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 634, 1587)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4399)
[M::mem_pestat] mean and std.dev: (1082.50, 1123.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5805)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695370 sequences (100000087 bp) in 2.785 CPU sec, 2.927 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283194, 26, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 247, 509)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1211)
[M::mem_pestat] mean and std.dev: (281.81, 200.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1562)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 249, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (276.30, 140.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 965)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (486, 1077, 2675)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7053)
[M::mem_pestat] mean and std.dev: (1593.85, 1566.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9242)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 319, 1241)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3249)
[M::mem_pestat] mean and std.dev: (814.55, 950.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4616)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695334 reads in 166.435 CPU sec, 5.300 real sec
[M::process] read 695510 sequences (100000240 bp) in 1.829 CPU sec, 1.838 real sec...
sorting block 46, #reads = 1077082 mem = 536880353 peak = 945381376
[M::mem_process_seqs] Processed 695592 reads in 113.726 CPU sec, 3.603 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 283305, 21, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 378, 1132)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2934)
[M::mem_pestat] mean and std.dev: (547.63, 486.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3835)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 248, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (275.95, 140.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 958)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (337, 553, 1551)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3979)
[M::mem_pestat] mean and std.dev: (784.05, 710.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5193)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (270, 520, 2610)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7290)
[M::mem_pestat] mean and std.dev: (1683.74, 2072.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9973)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 47, #reads = 1076063 mem = 536881335 peak = 952418304
[M::process] read 696324 sequences (100000204 bp) in 2.886 CPU sec, 3.022 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 282688, 14, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 272, 1042)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2828)
[M::mem_pestat] mean and std.dev: (536.68, 596.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3721)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (274.75, 139.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 953)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (425, 942, 1794)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4532)
[M::mem_pestat] mean and std.dev: (1162.77, 997.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5901)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 238, 1147)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3115)
[M::mem_pestat] mean and std.dev: (618.84, 692.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4099)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694232 sequences (100000288 bp) in 1.629 CPU sec, 1.630 real sec...
[M::mem_process_seqs] Processed 695370 reads in 170.012 CPU sec, 5.404 real sec
[M::mem_process_seqs] Processed 695510 reads in 113.845 CPU sec, 3.869 real sec
sorting block 48, #reads = 1076092 mem = 536878030 peak = 952418304
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 282913, 29, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 312, 1099)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3003)
[M::mem_pestat] mean and std.dev: (647.41, 701.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3955)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 248, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (275.60, 140.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 964)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 800, 2160)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6144)
[M::mem_pestat] mean and std.dev: (1007.19, 1004.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8136)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 392, 1088)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2790)
[M::mem_pestat] mean and std.dev: (586.14, 521.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3641)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693476 sequences (100000077 bp) in 2.966 CPU sec, 3.119 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 282664, 20, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (292, 575, 1155)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2881)
[M::mem_pestat] mean and std.dev: (556.29, 556.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3744)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 256, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 772)
[M::mem_pestat] mean and std.dev: (280.04, 139.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 973)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 387, 789)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1967)
[M::mem_pestat] mean and std.dev: (494.63, 408.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2556)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (275, 580, 1232)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3146)
[M::mem_pestat] mean and std.dev: (752.44, 678.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4103)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693730 sequences (100000176 bp) in 1.850 CPU sec, 1.853 real sec...
[M::mem_process_seqs] Processed 696324 reads in 176.110 CPU sec, 5.840 real sec
[M::mem_process_seqs] Processed 694232 reads in 114.826 CPU sec, 3.630 real sec
sorting block 49, #reads = 1074873 mem = 536878149 peak = 952418304
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 282965, 37, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (293, 532, 724)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1586)
[M::mem_pestat] mean and std.dev: (544.03, 369.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2023)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 258, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 779)
[M::mem_pestat] mean and std.dev: (282.56, 140.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 982)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (349, 1876, 2092)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5578)
[M::mem_pestat] mean and std.dev: (1665.31, 1510.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7709)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (275, 497, 834)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1952)
[M::mem_pestat] mean and std.dev: (482.69, 335.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2511)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694538 sequences (100000278 bp) in 2.659 CPU sec, 2.772 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 282587, 33, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (290, 497, 831)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1913)
[M::mem_pestat] mean and std.dev: (670.27, 547.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2861)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 259, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 782)
[M::mem_pestat] mean and std.dev: (282.73, 140.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 986)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 772, 2898)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8418)
[M::mem_pestat] mean and std.dev: (1286.52, 1571.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11178)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (124, 368, 2333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6751)
[M::mem_pestat] mean and std.dev: (777.03, 1068.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8960)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694952 sequences (100000274 bp) in 1.696 CPU sec, 1.697 real sec...
[M::mem_process_seqs] Processed 693476 reads in 164.894 CPU sec, 5.237 real sec
sorting block 50, #reads = 1076687 mem = 536881935 peak = 952418304
[M::mem_process_seqs] Processed 693730 reads in 112.464 CPU sec, 3.564 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 283068, 27, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 440, 1288)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3502)
[M::mem_pestat] mean and std.dev: (449.87, 355.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4609)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 254, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (278.37, 138.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 964)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (387, 734, 2381)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6369)
[M::mem_pestat] mean and std.dev: (1576.30, 1785.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8719)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (348, 487, 2640)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7224)
[M::mem_pestat] mean and std.dev: (941.66, 1030.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9516)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 51, #reads = 1077142 mem = 536880492 peak = 952418304
[M::process] read 691738 sequences (100000245 bp) in 2.601 CPU sec, 2.713 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 283875, 12, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 235, 591)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1423)
[M::mem_pestat] mean and std.dev: (388.83, 365.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1851)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 255, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 776)
[M::mem_pestat] mean and std.dev: (279.77, 140.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 979)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (609, 609, 1092)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2058)
[M::mem_pestat] mean and std.dev: (571.20, 293.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2541)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (271, 386, 894)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2140)
[M::mem_pestat] mean and std.dev: (615.90, 460.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2763)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695668 sequences (100000182 bp) in 1.681 CPU sec, 1.689 real sec...
[M::mem_process_seqs] Processed 694538 reads in 168.472 CPU sec, 5.622 real sec
[M::mem_process_seqs] Processed 694952 reads in 109.401 CPU sec, 3.469 real sec
sorting block 52, #reads = 1077600 mem = 536882092 peak = 952418304
[M::process] read 696058 sequences (100000171 bp) in 2.834 CPU sec, 2.954 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 283062, 37, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 324, 840)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2220)
[M::mem_pestat] mean and std.dev: (460.22, 381.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2910)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 253, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 778)
[M::mem_pestat] mean and std.dev: (279.38, 141.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 982)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 570, 2272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6434)
[M::mem_pestat] mean and std.dev: (1162.95, 1083.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8515)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 381, 1500)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4100)
[M::mem_pestat] mean and std.dev: (836.87, 897.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5400)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696714 sequences (100000016 bp) in 1.606 CPU sec, 1.607 real sec...
[M::mem_process_seqs] Processed 695668 reads in 100.413 CPU sec, 3.166 real sec
sorting block 53, #reads = 1077670 mem = 536881735 peak = 952418304
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 282236, 40, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (288, 571, 1576)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4152)
[M::mem_pestat] mean and std.dev: (807.48, 717.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5440)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 270, 389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 817)
[M::mem_pestat] mean and std.dev: (293.29, 146.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1031)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 497, 699)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1701)
[M::mem_pestat] mean and std.dev: (498.87, 332.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2202)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 286, 387)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (297.44, 84.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 813)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 283346, 28, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (310, 986, 2304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6292)
[M::mem_pestat] mean and std.dev: (1380.80, 1396.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8286)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 251, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 777)
[M::mem_pestat] mean and std.dev: (278.21, 141.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 981)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (83, 470, 603)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1643)
[M::mem_pestat] mean and std.dev: (421.64, 343.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2163)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (281, 599, 1733)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4637)
[M::mem_pestat] mean and std.dev: (1063.20, 1144.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6089)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 691738 reads in 258.255 CPU sec, 8.275 real sec
[M::process] read 696322 sequences (100000080 bp) in 2.518 CPU sec, 2.537 real sec...
[M::mem_process_seqs] Processed 696058 reads in 143.161 CPU sec, 4.546 real sec
sorting block 54, #reads = 1076537 mem = 536884381 peak = 952418304
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283755, 22, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 247, 976)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2566)
[M::mem_pestat] mean and std.dev: (443.06, 432.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3361)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 248, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 767)
[M::mem_pestat] mean and std.dev: (275.47, 139.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 968)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (31, 789, 2307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6859)
[M::mem_pestat] mean and std.dev: (1124.29, 1309.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9135)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 451, 993)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2499)
[M::mem_pestat] mean and std.dev: (494.83, 308.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3252)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696554 sequences (100000112 bp) in 2.826 CPU sec, 3.012 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 283973, 12, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 307, 1165)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3043)
[M::mem_pestat] mean and std.dev: (558.22, 674.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3982)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 759)
[M::mem_pestat] mean and std.dev: (275.20, 139.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 957)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (380, 1092, 2470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6650)
[M::mem_pestat] mean and std.dev: (1252.73, 1372.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8740)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 424, 659)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1519)
[M::mem_pestat] mean and std.dev: (398.24, 327.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1949)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696714 reads in 170.676 CPU sec, 5.425 real sec
[M::process] read 696202 sequences (100000184 bp) in 1.847 CPU sec, 1.841 real sec...
[M::mem_process_seqs] Processed 696322 reads in 115.480 CPU sec, 3.647 real sec
sorting block 55, #reads = 1077292 mem = 536877565 peak = 952418304
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 283424, 23, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 301, 580)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1334)
[M::mem_pestat] mean and std.dev: (305.15, 165.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1711)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 248, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 772)
[M::mem_pestat] mean and std.dev: (275.74, 140.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 975)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (466, 599, 1054)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2230)
[M::mem_pestat] mean and std.dev: (621.60, 402.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2818)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 276, 1032)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2744)
[M::mem_pestat] mean and std.dev: (537.86, 716.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3600)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694050 sequences (100000169 bp) in 2.522 CPU sec, 2.705 real sec...
[M::process] read 694050 sequences (100000183 bp) in 1.640 CPU sec, 1.638 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 283851, 29, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 502, 1704)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4644)
[M::mem_pestat] mean and std.dev: (951.84, 1136.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6114)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 249, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 768)
[M::mem_pestat] mean and std.dev: (277.03, 141.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 969)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (370, 610, 1832)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4756)
[M::mem_pestat] mean and std.dev: (922.27, 856.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6218)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (263, 432, 503)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 983)
[M::mem_pestat] mean and std.dev: (414.71, 238.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1369)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696554 reads in 176.059 CPU sec, 5.833 real sec
[M::mem_process_seqs] Processed 696202 reads in 115.918 CPU sec, 3.798 real sec
sorting block 56, #reads = 1077854 mem = 536880169 peak = 952418304
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 282875, 22, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 298, 1702)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4688)
[M::mem_pestat] mean and std.dev: (852.71, 818.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6181)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 257, 377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 793)
[M::mem_pestat] mean and std.dev: (284.39, 144.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1001)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (311, 956, 2378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6512)
[M::mem_pestat] mean and std.dev: (1821.82, 1884.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9358)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 386, 982)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2490)
[M::mem_pestat] mean and std.dev: (556.71, 455.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3244)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695804 sequences (100000137 bp) in 2.923 CPU sec, 3.082 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 283033, 20, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (387, 829, 1851)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4779)
[M::mem_pestat] mean and std.dev: (1033.46, 930.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6243)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 257, 377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 793)
[M::mem_pestat] mean and std.dev: (284.35, 144.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1001)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (619, 781, 3615)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9607)
[M::mem_pestat] mean and std.dev: (1593.10, 1406.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12603)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (260, 535, 599)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1277)
[M::mem_pestat] mean and std.dev: (462.77, 272.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1616)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695682 sequences (100000137 bp) in 1.571 CPU sec, 1.572 real sec...
[M::mem_process_seqs] Processed 694050 reads in 174.827 CPU sec, 5.653 real sec
sorting block 57, #reads = 1077019 mem = 536879837 peak = 952418304
[M::mem_process_seqs] Processed 694050 reads in 115.249 CPU sec, 3.654 real sec
sorting block 58, #reads = 1075858 mem = 536876172 peak = 1048264704
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 283326, 25, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 259, 966)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2498)
[M::mem_pestat] mean and std.dev: (522.41, 461.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3264)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 250, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 768)
[M::mem_pestat] mean and std.dev: (276.87, 140.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 969)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (281, 685, 1800)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4838)
[M::mem_pestat] mean and std.dev: (654.62, 531.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6357)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (319, 483, 891)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2035)
[M::mem_pestat] mean and std.dev: (570.32, 374.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2607)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694338 sequences (100000253 bp) in 2.525 CPU sec, 2.665 real sec...
[M::process] read 695264 sequences (100000012 bp) in 1.680 CPU sec, 1.681 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 283258, 26, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 394, 744)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1876)
[M::mem_pestat] mean and std.dev: (427.42, 371.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2442)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 251, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 772)
[M::mem_pestat] mean and std.dev: (278.67, 142.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 974)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (752, 953, 3366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8594)
[M::mem_pestat] mean and std.dev: (1727.38, 1787.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11208)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 408, 1289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3563)
[M::mem_pestat] mean and std.dev: (617.67, 553.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4700)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695804 reads in 174.151 CPU sec, 5.546 real sec
[M::mem_process_seqs] Processed 695682 reads in 126.732 CPU sec, 4.049 real sec
sorting block 59, #reads = 1076180 mem = 536879729 peak = 1048264704
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 282990, 29, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 356, 909)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2263)
[M::mem_pestat] mean and std.dev: (511.59, 482.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2940)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 257, 377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 793)
[M::mem_pestat] mean and std.dev: (284.66, 145.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1001)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 439, 1685)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4689)
[M::mem_pestat] mean and std.dev: (753.26, 964.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6191)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (380, 453, 912)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1976)
[M::mem_pestat] mean and std.dev: (531.42, 306.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2508)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695476 sequences (100000107 bp) in 2.656 CPU sec, 2.787 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 282899, 16, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 241, 513)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1255)
[M::mem_pestat] mean and std.dev: (379.49, 312.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1629)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 251, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 769)
[M::mem_pestat] mean and std.dev: (278.01, 140.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 970)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (341, 1128, 2208)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5942)
[M::mem_pestat] mean and std.dev: (1072.73, 1028.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7809)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (265, 497, 1802)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4876)
[M::mem_pestat] mean and std.dev: (1013.92, 1257.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6413)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695670 sequences (100000046 bp) in 1.649 CPU sec, 1.652 real sec...
[M::mem_process_seqs] Processed 694338 reads in 175.129 CPU sec, 5.573 real sec
sorting block 60, #reads = 1075745 mem = 536879905 peak = 1048264704
[M::mem_process_seqs] Processed 695264 reads in 122.033 CPU sec, 4.180 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 283865, 21, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 362, 1567)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4299)
[M::mem_pestat] mean and std.dev: (705.10, 645.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5665)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 249, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (276.59, 139.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 962)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (52, 634, 2089)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6163)
[M::mem_pestat] mean and std.dev: (957.67, 1195.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8200)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (355, 426, 662)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1276)
[M::mem_pestat] mean and std.dev: (421.39, 144.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1583)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695636 sequences (100000233 bp) in 2.415 CPU sec, 2.587 real sec...
[M::process] read 695626 sequences (100000191 bp) in 1.630 CPU sec, 1.632 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 282857, 35, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 315, 721)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1763)
[M::mem_pestat] mean and std.dev: (353.86, 277.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2284)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (274.36, 138.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 566, 1079)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2879)
[M::mem_pestat] mean and std.dev: (641.03, 628.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3779)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (325, 863, 1677)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4381)
[M::mem_pestat] mean and std.dev: (985.91, 867.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5733)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695476 reads in 178.453 CPU sec, 6.001 real sec
sorting block 61, #reads = 1075913 mem = 536888959 peak = 1048264704
[M::mem_process_seqs] Processed 695670 reads in 115.152 CPU sec, 3.670 real sec
sorting block 62, #reads = 1076334 mem = 536879219 peak = 1048264704
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 282811, 17, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (312, 357, 1053)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2535)
[M::mem_pestat] mean and std.dev: (456.36, 327.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3276)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (274.17, 138.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (292, 1166, 1216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3064)
[M::mem_pestat] mean and std.dev: (1042.65, 805.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4263)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 392, 869)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2217)
[M::mem_pestat] mean and std.dev: (666.59, 668.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3342)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695330 sequences (100000171 bp) in 2.671 CPU sec, 2.790 real sec...
[M::process] read 695112 sequences (100000279 bp) in 1.619 CPU sec, 1.620 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283138, 18, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 364, 977)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2595)
[M::mem_pestat] mean and std.dev: (410.00, 395.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3404)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (274.36, 138.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 744, 1300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3428)
[M::mem_pestat] mean and std.dev: (839.59, 692.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4492)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 615, 1348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3632)
[M::mem_pestat] mean and std.dev: (719.47, 622.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4774)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695636 reads in 176.668 CPU sec, 5.612 real sec
[M::mem_process_seqs] Processed 695626 reads in 118.411 CPU sec, 3.762 real sec
sorting block 63, #reads = 1074161 mem = 536878364 peak = 1048264704
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 283206, 21, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 332, 565)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1231)
[M::mem_pestat] mean and std.dev: (347.63, 240.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1564)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 759)
[M::mem_pestat] mean and std.dev: (275.61, 139.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 957)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 504, 882)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2318)
[M::mem_pestat] mean and std.dev: (521.10, 371.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3036)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 338, 2317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6511)
[M::mem_pestat] mean and std.dev: (1093.50, 1032.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8608)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695912 sequences (100000289 bp) in 2.364 CPU sec, 2.548 real sec...
[M::process] read 700680 sequences (100000198 bp) in 1.600 CPU sec, 1.599 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 282948, 23, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 350, 670)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1610)
[M::mem_pestat] mean and std.dev: (453.00, 325.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2080)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 249, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (276.59, 140.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 962)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (120, 723, 1349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3807)
[M::mem_pestat] mean and std.dev: (594.75, 511.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5036)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (280, 356, 1048)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2584)
[M::mem_pestat] mean and std.dev: (611.02, 489.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3352)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695330 reads in 168.951 CPU sec, 5.381 real sec
[M::mem_process_seqs] Processed 695112 reads in 120.889 CPU sec, 3.863 real sec
sorting block 64, #reads = 1074901 mem = 536879523 peak = 1048264704
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 283304, 21, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 496, 889)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2241)
[M::mem_pestat] mean and std.dev: (640.96, 539.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2917)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 246, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (274.52, 139.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 956)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (305, 770, 2911)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8123)
[M::mem_pestat] mean and std.dev: (1465.11, 2244.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10729)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 414, 1502)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4076)
[M::mem_pestat] mean and std.dev: (853.82, 869.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5363)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697918 sequences (100000255 bp) in 2.562 CPU sec, 2.661 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 285250, 14, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 386, 831)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2151)
[M::mem_pestat] mean and std.dev: (520.91, 453.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2811)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 231, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 723)
[M::mem_pestat] mean and std.dev: (261.70, 135.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 912)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 538, 672)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1536)
[M::mem_pestat] mean and std.dev: (440.69, 299.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1968)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 391, 1668)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4716)
[M::mem_pestat] mean and std.dev: (765.43, 854.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6240)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698352 sequences (100000270 bp) in 1.658 CPU sec, 1.658 real sec...
[M::mem_process_seqs] Processed 695912 reads in 172.370 CPU sec, 5.480 real sec
sorting block 65, #reads = 1074247 mem = 536882341 peak = 1048264704
[M::mem_process_seqs] Processed 700680 reads in 122.007 CPU sec, 3.874 real sec
sorting block 66, #reads = 1074661 mem = 536879174 peak = 1048264704
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 284953, 21, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 169, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 454)
[M::mem_pestat] mean and std.dev: (186.52, 60.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 552)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 242, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 776)
[M::mem_pestat] mean and std.dev: (275.85, 145.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 981)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (458, 707, 859)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1661)
[M::mem_pestat] mean and std.dev: (650.37, 368.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2125)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 298, 938)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2416)
[M::mem_pestat] mean and std.dev: (529.25, 462.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3155)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699424 sequences (100000074 bp) in 2.558 CPU sec, 2.703 real sec...
[M::process] read 699316 sequences (100000144 bp) in 1.879 CPU sec, 1.879 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 284981, 28, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 292, 488)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1188)
[M::mem_pestat] mean and std.dev: (314.29, 235.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1538)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 241, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 766)
[M::mem_pestat] mean and std.dev: (273.55, 143.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 968)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 768, 1405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3827)
[M::mem_pestat] mean and std.dev: (732.27, 697.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5038)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (271, 451, 869)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2065)
[M::mem_pestat] mean and std.dev: (495.45, 295.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2663)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697918 reads in 183.603 CPU sec, 5.861 real sec
[M::mem_process_seqs] Processed 698352 reads in 126.253 CPU sec, 4.028 real sec
sorting block 67, #reads = 1074843 mem = 536880716 peak = 1048264704
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 285094, 22, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 211, 433)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 941)
[M::mem_pestat] mean and std.dev: (273.57, 132.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1195)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 236, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 740)
[M::mem_pestat] mean and std.dev: (266.71, 138.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 934)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 385, 741)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1835)
[M::mem_pestat] mean and std.dev: (545.24, 518.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2619)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (287, 541, 1452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3782)
[M::mem_pestat] mean and std.dev: (747.93, 734.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4947)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698572 sequences (100000104 bp) in 2.598 CPU sec, 2.696 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 285192, 13, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 333, 949)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2387)
[M::mem_pestat] mean and std.dev: (601.53, 551.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3106)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 237, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 747)
[M::mem_pestat] mean and std.dev: (268.16, 139.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 943)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (638, 919, 6085)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 16979)
[M::mem_pestat] mean and std.dev: (2555.46, 3010.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 22426)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 221, 547)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1303)
[M::mem_pestat] mean and std.dev: (335.29, 241.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1681)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695998 sequences (100000197 bp) in 2.108 CPU sec, 2.104 real sec...
[M::mem_process_seqs] Processed 699424 reads in 181.899 CPU sec, 5.765 real sec
[M::mem_process_seqs] Processed 699316 reads in 120.154 CPU sec, 3.801 real sec
sorting block 68, #reads = 1076949 mem = 536880800 peak = 1048264704
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 284755, 21, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 332, 614)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1436)
[M::mem_pestat] mean and std.dev: (382.29, 348.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1847)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 239, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (269.66, 140.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 951)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (437, 1199, 4241)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11849)
[M::mem_pestat] mean and std.dev: (1803.48, 1696.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 15653)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 343, 1288)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3440)
[M::mem_pestat] mean and std.dev: (693.40, 713.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4516)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699914 sequences (100000149 bp) in 2.547 CPU sec, 2.664 real sec...
[M::process] read 699804 sequences (100000294 bp) in 2.009 CPU sec, 2.012 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 284478, 21, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 324, 426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 934)
[M::mem_pestat] mean and std.dev: (318.77, 188.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1188)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 249, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 791)
[M::mem_pestat] mean and std.dev: (280.63, 146.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1000)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 324, 1148)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3156)
[M::mem_pestat] mean and std.dev: (454.53, 418.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4160)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 424, 2746)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7808)
[M::mem_pestat] mean and std.dev: (1587.85, 2071.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10339)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698572 reads in 183.380 CPU sec, 6.114 real sec
sorting block 69, #reads = 1075874 mem = 536881058 peak = 1048264704
[M::mem_process_seqs] Processed 695998 reads in 118.907 CPU sec, 3.776 real sec
sorting block 70, #reads = 1075482 mem = 536881116 peak = 1048264704
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 285295, 14, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 381, 703)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1579)
[M::mem_pestat] mean and std.dev: (432.84, 301.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2017)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 235, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 739)
[M::mem_pestat] mean and std.dev: (265.97, 138.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 933)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 365, 688)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1788)
[M::mem_pestat] mean and std.dev: (283.82, 176.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2338)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 345, 727)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1737)
[M::mem_pestat] mean and std.dev: (488.61, 414.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2242)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698292 sequences (100000235 bp) in 2.616 CPU sec, 2.716 real sec...
[M::process] read 696314 sequences (100000088 bp) in 1.560 CPU sec, 1.560 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 285503, 18, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 329, 1115)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2969)
[M::mem_pestat] mean and std.dev: (671.65, 742.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3896)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 734)
[M::mem_pestat] mean and std.dev: (265.49, 137.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 926)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (99, 272, 941)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2625)
[M::mem_pestat] mean and std.dev: (309.00, 342.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3467)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 470, 759)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1957)
[M::mem_pestat] mean and std.dev: (418.10, 380.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2556)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699914 reads in 184.957 CPU sec, 5.877 real sec
[M::mem_process_seqs] Processed 699804 reads in 124.585 CPU sec, 3.962 real sec
sorting block 71, #reads = 1076020 mem = 536879277 peak = 1048264704
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 284865, 19, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 547, 847)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2099)
[M::mem_pestat] mean and std.dev: (576.67, 455.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2725)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 240, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (271.76, 141.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 960)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (382, 856, 2817)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7687)
[M::mem_pestat] mean and std.dev: (1639.11, 1722.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10122)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 286, 969)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2425)
[M::mem_pestat] mean and std.dev: (533.21, 642.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3153)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695840 sequences (100000291 bp) in 2.545 CPU sec, 2.656 real sec...
[M::process] read 697218 sequences (100000102 bp) in 1.730 CPU sec, 1.733 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 283747, 23, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 318, 799)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2027)
[M::mem_pestat] mean and std.dev: (480.42, 407.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2641)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 248, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 782)
[M::mem_pestat] mean and std.dev: (279.35, 145.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 988)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 628, 2701)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7689)
[M::mem_pestat] mean and std.dev: (1398.59, 1834.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10183)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 263, 594)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1456)
[M::mem_pestat] mean and std.dev: (356.75, 272.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1887)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698292 reads in 192.489 CPU sec, 6.313 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 283518, 30, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 326, 745)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1877)
[M::mem_pestat] mean and std.dev: (487.25, 387.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2443)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 250, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 784)
[M::process] read 694976 sequences (100000027 bp) in 2.171 CPU sec, 2.174 real sec...
[M::mem_pestat] mean and std.dev: (280.73, 145.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 990)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (476, 695, 1164)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2540)
[M::mem_pestat] mean and std.dev: (805.66, 687.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3555)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 414, 1323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3547)
[M::mem_pestat] mean and std.dev: (447.70, 389.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4659)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695840 reads in 103.515 CPU sec, 3.313 real sec
sorting block 72, #reads = 1074984 mem = 536876520 peak = 1048264704
[M::mem_process_seqs] Processed 696314 reads in 256.444 CPU sec, 8.190 real sec
sorting block 73, #reads = 1071756 mem = 536879480 peak = 1099161600
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 283384, 19, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 490, 1430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3880)
[M::mem_pestat] mean and std.dev: (779.37, 769.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5105)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 244, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 768)
[M::mem_pestat] mean and std.dev: (274.84, 142.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 970)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 465, 694)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1658)
[M::mem_pestat] mean and std.dev: (432.47, 316.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2140)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 458, 1339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3545)
[M::mem_pestat] mean and std.dev: (664.81, 678.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4648)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695180 sequences (100000036 bp) in 2.697 CPU sec, 2.811 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 283070, 27, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 928, 1466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3920)
[M::mem_pestat] mean and std.dev: (747.38, 571.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5147)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 252, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 785)
[M::mem_pestat] mean and std.dev: (281.24, 144.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 991)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (119, 491, 2747)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8003)
[M::mem_pestat] mean and std.dev: (1486.81, 1867.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10631)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 267, 667)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1669)
[M::mem_pestat] mean and std.dev: (316.29, 221.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2170)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695450 sequences (100000019 bp) in 1.730 CPU sec, 1.733 real sec...
[M::mem_process_seqs] Processed 697218 reads in 217.247 CPU sec, 6.944 real sec
[M::process] read 693820 sequences (100000097 bp) in 1.812 CPU sec, 1.815 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 282985, 41, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 318, 868)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2158)
[M::mem_pestat] mean and std.dev: (482.45, 433.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2803)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 250, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 772)
[M::mem_pestat] mean and std.dev: (278.15, 141.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 974)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (383, 664, 968)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2138)
[M::mem_pestat] mean and std.dev: (563.79, 280.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2723)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (327, 517, 1355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3411)
[M::mem_pestat] mean and std.dev: (702.71, 571.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4439)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695180 reads in 109.816 CPU sec, 3.556 real sec
sorting block 74, #reads = 1072189 mem = 536882784 peak = 1099161600
[M::mem_process_seqs] Processed 694976 reads in 270.924 CPU sec, 8.683 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 282997, 22, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (286, 421, 552)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1084)
[M::mem_pestat] mean and std.dev: (447.28, 221.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1350)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 249, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 769)
[M::mem_pestat] mean and std.dev: (277.78, 141.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 970)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 708, 1711)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4655)
[M::mem_pestat] mean and std.dev: (711.89, 732.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6127)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 360, 1258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3318)
[M::mem_pestat] mean and std.dev: (603.73, 561.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4348)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 75, #reads = 1072096 mem = 536880978 peak = 1099161600
[M::process] read 696738 sequences (100000046 bp) in 2.557 CPU sec, 2.679 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 282506, 22, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 509, 935)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2433)
[M::mem_pestat] mean and std.dev: (643.14, 518.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3182)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 256, 379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 801)
[M::mem_pestat] mean and std.dev: (285.46, 146.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1012)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 607, 1074)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2820)
[M::mem_pestat] mean and std.dev: (606.00, 551.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3693)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 407, 1385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3729)
[M::mem_pestat] mean and std.dev: (747.98, 763.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4901)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695534 sequences (100000265 bp) in 1.640 CPU sec, 1.635 real sec...
[M::mem_process_seqs] Processed 695450 reads in 211.827 CPU sec, 6.738 real sec
[M::mem_process_seqs] Processed 693820 reads in 128.190 CPU sec, 4.067 real sec
sorting block 76, #reads = 1071914 mem = 536886838 peak = 1099161600
[M::process] read 695002 sequences (100000278 bp) in 2.458 CPU sec, 2.629 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 283112, 18, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 377, 767)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1891)
[M::mem_pestat] mean and std.dev: (478.91, 364.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2453)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 243, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (273.03, 139.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 951)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 382, 986)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2474)
[M::mem_pestat] mean and std.dev: (497.59, 403.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3218)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (258, 513, 1491)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3957)
[M::mem_pestat] mean and std.dev: (765.39, 677.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5190)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696106 sequences (100000146 bp) in 1.783 CPU sec, 1.796 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 282603, 23, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 348, 1133)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3001)
[M::mem_pestat] mean and std.dev: (670.74, 673.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3935)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 250, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 778)
[M::mem_pestat] mean and std.dev: (279.84, 143.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 982)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (122, 219, 919)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2513)
[M::mem_pestat] mean and std.dev: (528.04, 558.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3310)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 346, 1937)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5397)
[M::mem_pestat] mean and std.dev: (745.24, 1055.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7127)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 282832, 28, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 285, 570)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1346)
[M::mem_pestat] mean and std.dev: (395.70, 282.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1734)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 246, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 762)
[M::mem_pestat] mean and std.dev: (275.73, 140.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 961)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (740, 1569, 1984)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4472)
[M::mem_pestat] mean and std.dev: (1419.44, 1159.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6059)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (286, 625, 1451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3781)
[M::mem_pestat] mean and std.dev: (671.68, 535.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4946)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696738 reads in 275.090 CPU sec, 9.086 real sec
[M::mem_process_seqs] Processed 695002 reads in 205.534 CPU sec, 6.582 real sec
sorting block 77, #reads = 1071962 mem = 536881861 peak = 1099161600
[M::mem_process_seqs] Processed 695534 reads in 228.581 CPU sec, 7.339 real sec
sorting block 78, #reads = 1071154 mem = 536877483 peak = 1099161600
[M::process] read 696042 sequences (100000011 bp) in 2.711 CPU sec, 2.905 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 282790, 29, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (274, 516, 924)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2224)
[M::mem_pestat] mean and std.dev: (510.06, 370.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2874)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 245, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (275.26, 141.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 964)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (452, 781, 900)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1796)
[M::mem_pestat] mean and std.dev: (707.31, 377.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2244)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 308, 778)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1942)
[M::mem_pestat] mean and std.dev: (471.78, 370.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2524)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696106 reads in 105.460 CPU sec, 3.467 real sec
[M::process] read 699162 sequences (100000156 bp) in 2.883 CPU sec, 3.111 real sec...
sorting block 79, #reads = 1071426 mem = 536879185 peak = 1099161600
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 283009, 17, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 298, 691)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1655)
[M::mem_pestat] mean and std.dev: (393.45, 295.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2137)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 245, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (275.58, 142.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 964)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 957)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2563)
[M::mem_pestat] mean and std.dev: (485.06, 492.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3366)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 375, 1030)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2576)
[M::mem_pestat] mean and std.dev: (715.26, 628.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3349)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703700 sequences (100000095 bp) in 1.996 CPU sec, 2.017 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 284683, 23, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 386, 762)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1858)
[M::mem_pestat] mean and std.dev: (498.69, 373.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2406)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 238, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (268.92, 139.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 947)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 638, 1301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3375)
[M::mem_pestat] mean and std.dev: (719.36, 644.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4412)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 267, 391)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 823)
[M::mem_pestat] mean and std.dev: (234.79, 91.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1039)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701210 sequences (100000002 bp) in 1.580 CPU sec, 1.584 real sec...
[M::mem_process_seqs] Processed 696042 reads in 223.323 CPU sec, 7.120 real sec
[M::mem_process_seqs] Processed 699162 reads in 138.330 CPU sec, 4.376 real sec
sorting block 80, #reads = 1071871 mem = 536877750 peak = 1099161600
[M::process] read 700744 sequences (100000023 bp) in 2.395 CPU sec, 2.514 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 286073, 17, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (302, 370, 727)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1577)
[M::mem_pestat] mean and std.dev: (487.12, 319.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2002)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 226, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 711)
[M::mem_pestat] mean and std.dev: (256.30, 132.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 897)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 770, 1507)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4097)
[M::mem_pestat] mean and std.dev: (972.00, 919.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5392)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 329, 570)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1268)
[M::mem_pestat] mean and std.dev: (378.60, 206.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1617)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700444 sequences (100000094 bp) in 1.647 CPU sec, 1.649 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 285908, 25, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 364, 1187)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3133)
[M::mem_pestat] mean and std.dev: (556.73, 517.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4106)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 233, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 732)
[M::mem_pestat] mean and std.dev: (263.08, 135.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 924)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 546, 815)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2017)
[M::mem_pestat] mean and std.dev: (503.39, 369.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2618)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 630, 1013)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2605)
[M::mem_pestat] mean and std.dev: (639.44, 431.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3401)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703700 reads in 210.484 CPU sec, 6.715 real sec
sorting block 81, #reads = 1068299 mem = 536886544 peak = 1099161600
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 285812, 33, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 735, 883)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2191)
[M::mem_pestat] mean and std.dev: (533.57, 387.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2845)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 234, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 736)
[M::mem_pestat] mean and std.dev: (263.93, 135.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 929)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (272, 585, 651)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1409)
[M::mem_pestat] mean and std.dev: (444.53, 270.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1788)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (263, 691, 2532)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7070)
[M::mem_pestat] mean and std.dev: (1314.09, 1476.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9339)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698870 sequences (100000102 bp) in 2.152 CPU sec, 2.153 real sec...
[M::mem_process_seqs] Processed 701210 reads in 223.841 CPU sec, 7.109 real sec
[M::mem_process_seqs] Processed 700744 reads in 248.248 CPU sec, 8.181 real sec
sorting block 82, #reads = 1067694 mem = 536881114 peak = 1099161600
[M::process] read 698722 sequences (100000019 bp) in 2.319 CPU sec, 2.733 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 285594, 24, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (319, 833, 1078)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2596)
[M::mem_pestat] mean and std.dev: (796.20, 544.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3355)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 235, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 730)
[M::mem_pestat] mean and std.dev: (263.12, 134.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 921)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (305, 441, 2208)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6014)
[M::mem_pestat] mean and std.dev: (982.87, 1014.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7917)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (260, 273, 381)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (18, 623)
[M::mem_pestat] mean and std.dev: (281.78, 100.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 744)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699840 sequences (100000174 bp) in 1.910 CPU sec, 1.915 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 285304, 25, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (288, 442, 2495)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6909)
[M::mem_pestat] mean and std.dev: (1128.77, 1056.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9116)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 240, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (269.26, 137.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 948)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (488, 1286, 2090)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5294)
[M::mem_pestat] mean and std.dev: (1376.67, 1084.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6896)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (140, 211, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1094)
[M::mem_pestat] mean and std.dev: (252.85, 160.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1412)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700444 reads in 196.355 CPU sec, 6.500 real sec
[M::mem_process_seqs] Processed 698870 reads in 215.817 CPU sec, 7.255 real sec
sorting block 83, #reads = 1070633 mem = 536879490 peak = 1099161600
[M::process] read 699862 sequences (100000073 bp) in 2.226 CPU sec, 2.344 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 284846, 13, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 320, 1374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3730)
[M::mem_pestat] mean and std.dev: (856.42, 994.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4908)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 239, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 742)
[M::mem_pestat] mean and std.dev: (268.14, 137.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 936)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (319, 385, 1877)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4993)
[M::mem_pestat] mean and std.dev: (737.25, 823.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6551)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 414, 2593)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7353)
[M::mem_pestat] mean and std.dev: (1070.53, 1397.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9733)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698248 sequences (100000006 bp) in 1.546 CPU sec, 1.554 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 285441, 25, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 213, 420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 962)
[M::mem_pestat] mean and std.dev: (271.04, 165.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1233)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 236, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 740)
[M::mem_pestat] mean and std.dev: (265.73, 136.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 934)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 516, 1144)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2976)
[M::mem_pestat] mean and std.dev: (681.24, 608.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3892)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 271, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 931)
[M::mem_pestat] mean and std.dev: (260.54, 114.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1179)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 285393, 24, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (125, 251, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1127)
[M::mem_pestat] mean and std.dev: (269.46, 211.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1461)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 734)
[M::mem_pestat] mean and std.dev: (264.87, 135.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 926)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 919, 3016)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8582)
[M::mem_pestat] mean and std.dev: (2061.54, 2427.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11771)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 417, 1451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3899)
[M::mem_pestat] mean and std.dev: (603.23, 702.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5123)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698722 reads in 272.591 CPU sec, 8.842 real sec
sorting block 84, #reads = 1072315 mem = 536880124 peak = 1099161600
[M::mem_process_seqs] Processed 699862 reads in 212.968 CPU sec, 6.841 real sec
[M::mem_process_seqs] Processed 699840 reads in 232.383 CPU sec, 7.480 real sec
sorting block 85, #reads = 1072588 mem = 536883430 peak = 1099161600
[M::process] read 695012 sequences (100000134 bp) in 2.598 CPU sec, 2.776 real sec...
[M::process] read 697880 sequences (100000181 bp) in 1.992 CPU sec, 2.067 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 282877, 18, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 743, 2428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6870)
[M::mem_pestat] mean and std.dev: (1109.61, 1043.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9091)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 253, 378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 800)
[M::mem_pestat] mean and std.dev: (283.55, 146.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1011)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (351, 766, 1799)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4695)
[M::mem_pestat] mean and std.dev: (1359.11, 1391.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6925)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 369, 665)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1597)
[M::mem_pestat] mean and std.dev: (430.66, 349.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2063)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695012 reads in 105.417 CPU sec, 3.310 real sec
[M::process] read 696480 sequences (100000025 bp) in 1.795 CPU sec, 1.798 real sec...
sorting block 86, #reads = 1071931 mem = 536884119 peak = 1099161600
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 284998, 16, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 318, 685)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1569)
[M::mem_pestat] mean and std.dev: (453.81, 295.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2011)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 240, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 752)
[M::mem_pestat] mean and std.dev: (270.03, 138.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (268, 336, 933)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2263)
[M::mem_pestat] mean and std.dev: (379.08, 248.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2928)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 350, 743)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1821)
[M::mem_pestat] mean and std.dev: (442.74, 348.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2360)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 284574, 22, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (273, 405, 1258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3228)
[M::mem_pestat] mean and std.dev: (508.56, 452.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4213)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 243, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (272.91, 141.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 965)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (585, 1073, 1631)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3723)
[M::mem_pestat] mean and std.dev: (1021.80, 449.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4769)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (282, 358, 818)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1890)
[M::mem_pestat] mean and std.dev: (583.00, 488.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2537)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696442 sequences (100000289 bp) in 1.779 CPU sec, 1.779 real sec...
[M::mem_process_seqs] Processed 698248 reads in 299.437 CPU sec, 9.530 real sec
[M::mem_process_seqs] Processed 697880 reads in 149.850 CPU sec, 4.868 real sec
sorting block 87, #reads = 1070900 mem = 536878241 peak = 1099161600
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 283392, 14, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 454, 675)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1613)
[M::mem_pestat] mean and std.dev: (358.65, 233.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2082)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 247, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 779)
[M::mem_pestat] mean and std.dev: (277.60, 144.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 984)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 388, 803)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2027)
[M::mem_pestat] mean and std.dev: (549.00, 436.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2639)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 293, 822)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1978)
[M::mem_pestat] mean and std.dev: (505.24, 459.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2556)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695932 sequences (100000261 bp) in 2.431 CPU sec, 2.590 real sec...
[M::process] read 693524 sequences (100000167 bp) in 1.809 CPU sec, 1.811 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 283308, 27, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 363, 835)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2155)
[M::mem_pestat] mean and std.dev: (511.24, 447.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2815)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 247, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 776)
[M::mem_pestat] mean and std.dev: (277.33, 143.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 980)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (301, 732, 2043)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5527)
[M::mem_pestat] mean and std.dev: (1216.41, 1178.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7269)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 360, 691)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1737)
[M::mem_pestat] mean and std.dev: (423.60, 299.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2260)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696480 reads in 190.265 CPU sec, 6.166 real sec
sorting block 88, #reads = 1072948 mem = 536879892 peak = 1099161600
[M::mem_process_seqs] Processed 696442 reads in 124.516 CPU sec, 4.081 real sec
sorting block 89, #reads = 1071516 mem = 536881281 peak = 1099161600
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 283098, 22, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 392, 731)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1733)
[M::mem_pestat] mean and std.dev: (431.33, 326.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2234)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 774)
[M::mem_pestat] mean and std.dev: (277.75, 143.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 977)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (320, 614, 1281)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3203)
[M::mem_pestat] mean and std.dev: (785.76, 709.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4164)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (298, 821, 1396)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3592)
[M::mem_pestat] mean and std.dev: (873.30, 764.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4690)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695872 sequences (100000216 bp) in 2.509 CPU sec, 2.651 real sec...
[M::process] read 696580 sequences (100000089 bp) in 1.719 CPU sec, 1.719 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 282441, 23, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (298, 674, 886)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2062)
[M::mem_pestat] mean and std.dev: (581.03, 344.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2650)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 257, 381)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 805)
[M::mem_pestat] mean and std.dev: (286.95, 148.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1017)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (294, 294, 747)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1653)
[M::mem_pestat] mean and std.dev: (480.81, 396.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2106)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (268, 754, 1099)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2761)
[M::mem_pestat] mean and std.dev: (610.70, 471.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3592)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695932 reads in 189.310 CPU sec, 6.126 real sec
[M::mem_process_seqs] Processed 693524 reads in 125.332 CPU sec, 4.111 real sec
sorting block 90, #reads = 1071746 mem = 536885631 peak = 1099161600
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 282681, 20, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 421, 763)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1815)
[M::mem_pestat] mean and std.dev: (414.65, 287.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2341)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 771)
[M::mem_pestat] mean and std.dev: (277.07, 142.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 973)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (286, 539, 1282)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3274)
[M::mem_pestat] mean and std.dev: (539.82, 510.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4270)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 509, 975)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2511)
[M::mem_pestat] mean and std.dev: (527.78, 411.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3279)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696024 sequences (100000269 bp) in 2.517 CPU sec, 2.633 real sec...
[M::process] read 696548 sequences (100000148 bp) in 1.740 CPU sec, 1.737 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 283263, 20, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 417, 883)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2229)
[M::mem_pestat] mean and std.dev: (498.23, 441.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2902)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 246, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 767)
[M::mem_pestat] mean and std.dev: (275.89, 142.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 968)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (47, 225, 709)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2033)
[M::mem_pestat] mean and std.dev: (429.37, 552.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2695)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 350, 1184)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3176)
[M::mem_pestat] mean and std.dev: (572.21, 507.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4172)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695872 reads in 192.785 CPU sec, 6.250 real sec
[M::mem_process_seqs] Processed 696580 reads in 125.971 CPU sec, 4.009 real sec
sorting block 91, #reads = 1071271 mem = 536878840 peak = 1099161600
[M::process] read 696686 sequences (100000190 bp) in 2.534 CPU sec, 2.666 real sec...
[M::process] read 699742 sequences (100000172 bp) in 1.868 CPU sec, 1.866 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 283064, 35, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 292, 495)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1155)
[M::mem_pestat] mean and std.dev: (290.22, 169.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1485)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 769)
[M::mem_pestat] mean and std.dev: (275.96, 143.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 971)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (718, 732, 826)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (502, 1042)
[M::mem_pestat] mean and std.dev: (725.54, 70.28)
[M::mem_pestat] low and high boundaries for proper pairs: (394, 1150)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (260, 731, 2375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6605)
[M::mem_pestat] mean and std.dev: (1125.11, 1291.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8720)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696548 reads in 108.193 CPU sec, 3.455 real sec
sorting block 92, #reads = 1071407 mem = 536879799 peak = 1099161600
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 283098, 24, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (322, 387, 1261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3139)
[M::mem_pestat] mean and std.dev: (714.68, 627.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4078)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 247, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 776)
[M::mem_pestat] mean and std.dev: (277.98, 144.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 980)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (530, 971, 1585)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3695)
[M::mem_pestat] mean and std.dev: (1044.22, 741.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4750)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (456, 825, 1853)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4647)
[M::mem_pestat] mean and std.dev: (1278.66, 1261.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6326)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 282675, 34, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 400, 1014)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2568)
[M::mem_pestat] mean and std.dev: (621.38, 552.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3345)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 243, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (274.59, 142.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 963)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (81, 470, 1005)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2853)
[M::mem_pestat] mean and std.dev: (618.28, 611.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3777)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 521, 913)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2227)
[M::mem_pestat] mean and std.dev: (610.39, 538.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2884)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699192 sequences (100000215 bp) in 1.891 CPU sec, 1.897 real sec...
[M::mem_process_seqs] Processed 696024 reads in 309.144 CPU sec, 9.965 real sec
[M::mem_process_seqs] Processed 696686 reads in 160.110 CPU sec, 5.277 real sec
sorting block 93, #reads = 1070343 mem = 536879622 peak = 1099161600
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 283761, 21, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 549, 1096)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2838)
[M::mem_pestat] mean and std.dev: (697.46, 651.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3709)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 234, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 731)
[M::mem_pestat] mean and std.dev: (264.37, 136.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 922)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (268, 850, 1116)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2812)
[M::mem_pestat] mean and std.dev: (712.90, 513.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3660)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 293, 658)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1570)
[M::mem_pestat] mean and std.dev: (376.83, 227.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2026)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698478 sequences (100000066 bp) in 2.779 CPU sec, 3.013 real sec...
[M::process] read 697998 sequences (100000157 bp) in 1.807 CPU sec, 1.809 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 284956, 23, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 308, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 978)
[M::mem_pestat] mean and std.dev: (315.47, 147.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1236)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 238, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 744)
[M::mem_pestat] mean and std.dev: (267.65, 137.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 939)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (396, 573, 1109)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2535)
[M::mem_pestat] mean and std.dev: (791.96, 638.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3347)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 607, 1544)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4184)
[M::mem_pestat] mean and std.dev: (996.48, 786.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5504)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699742 reads in 210.485 CPU sec, 6.810 real sec
sorting block 94, #reads = 1062763 mem = 536879547 peak = 1099161600
[M::mem_process_seqs] Processed 699192 reads in 129.443 CPU sec, 4.120 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 285239, 21, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 335, 487)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1061)
[M::mem_pestat] mean and std.dev: (345.09, 180.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1348)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 240, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (270.32, 139.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 952)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 375, 612)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1416)
[M::mem_pestat] mean and std.dev: (393.05, 329.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1818)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 381, 883)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2231)
[M::mem_pestat] mean and std.dev: (607.71, 569.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2905)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697652 sequences (100000063 bp) in 2.570 CPU sec, 2.744 real sec...
[M::process] read 693908 sequences (100000065 bp) in 1.829 CPU sec, 1.829 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 284999, 18, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 466, 1087)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2781)
[M::mem_pestat] mean and std.dev: (725.00, 614.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3628)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 242, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (272.21, 140.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 961)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (550, 771, 1536)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3508)
[M::mem_pestat] mean and std.dev: (1003.53, 874.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4503)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 191, 922)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2466)
[M::mem_pestat] mean and std.dev: (550.64, 633.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3238)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698478 reads in 184.952 CPU sec, 6.005 real sec
sorting block 95, #reads = 1074106 mem = 536880818 peak = 1099161600
[M::mem_process_seqs] Processed 697998 reads in 122.225 CPU sec, 3.997 real sec
sorting block 96, #reads = 1076426 mem = 536877966 peak = 1099161600
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 284825, 17, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (259, 682, 1299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3379)
[M::mem_pestat] mean and std.dev: (1070.50, 1083.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5404)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 244, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (273.87, 141.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 966)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 646, 1424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3810)
[M::mem_pestat] mean and std.dev: (813.41, 598.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5003)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (323, 389, 485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 809)
[M::mem_pestat] mean and std.dev: (356.10, 151.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 971)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698596 sequences (100000108 bp) in 2.782 CPU sec, 2.959 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 283313, 22, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 391, 667)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1551)
[M::mem_pestat] mean and std.dev: (432.20, 267.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1993)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 261, 383)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 809)
[M::mem_pestat] mean and std.dev: (287.44, 145.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1022)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1204, 4208, 4208)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10216)
[M::mem_pestat] mean and std.dev: (3301.18, 2567.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13571)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 436, 1762)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4778)
[M::mem_pestat] mean and std.dev: (855.38, 751.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6286)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698760 sequences (100000042 bp) in 1.678 CPU sec, 1.681 real sec...
[M::mem_process_seqs] Processed 697652 reads in 183.338 CPU sec, 5.947 real sec
[M::mem_process_seqs] Processed 693908 reads in 119.042 CPU sec, 3.891 real sec
sorting block 97, #reads = 1076874 mem = 536876687 peak = 1099161600
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 285205, 22, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 258, 1038)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2710)
[M::mem_pestat] mean and std.dev: (530.81, 491.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3546)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 240, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (268.99, 137.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 944)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 437, 588)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1404)
[M::mem_pestat] mean and std.dev: (407.68, 320.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1812)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 360, 783)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2059)
[M::mem_pestat] mean and std.dev: (444.09, 327.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2697)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699160 sequences (100000114 bp) in 2.714 CPU sec, 2.871 real sec...
[M::process] read 698052 sequences (100000075 bp) in 1.860 CPU sec, 1.854 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 285540, 26, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 481, 1266)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3408)
[M::mem_pestat] mean and std.dev: (735.80, 767.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4479)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 239, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 741)
[M::mem_pestat] mean and std.dev: (266.79, 135.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 935)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (121, 1258, 3223)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9427)
[M::mem_pestat] mean and std.dev: (1707.92, 1668.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12529)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 251, 637)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1581)
[M::mem_pestat] mean and std.dev: (356.34, 286.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2053)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698596 reads in 186.079 CPU sec, 6.029 real sec
[M::mem_process_seqs] Processed 698760 reads in 122.241 CPU sec, 3.985 real sec
sorting block 98, #reads = 1075403 mem = 536879649 peak = 1099161600
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 284300, 25, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 323, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1044)
[M::mem_pestat] mean and std.dev: (346.09, 239.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1330)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 237, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 735)
[M::mem_pestat] mean and std.dev: (265.24, 134.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 927)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 797, 3096)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8826)
[M::mem_pestat] mean and std.dev: (1421.91, 1525.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11691)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 331, 706)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1730)
[M::mem_pestat] mean and std.dev: (416.70, 294.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2242)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697852 sequences (100000032 bp) in 2.752 CPU sec, 2.906 real sec...
[M::process] read 696816 sequences (100000003 bp) in 1.610 CPU sec, 1.605 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 284567, 12, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 310, 824)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2012)
[M::mem_pestat] mean and std.dev: (358.83, 244.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2606)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 241, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 746)
[M::mem_pestat] mean and std.dev: (268.81, 136.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 941)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (421, 800, 1823)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4627)
[M::mem_pestat] mean and std.dev: (968.18, 909.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6029)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (269, 503, 736)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1670)
[M::mem_pestat] mean and std.dev: (481.11, 272.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2137)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699160 reads in 186.065 CPU sec, 6.017 real sec
sorting block 99, #reads = 1077400 mem = 536879275 peak = 1099161600
[M::mem_process_seqs] Processed 698052 reads in 123.720 CPU sec, 4.073 real sec
sorting block 100, #reads = 1075026 mem = 536878850 peak = 1099161600
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 284370, 26, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 404, 838)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2160)
[M::mem_pestat] mean and std.dev: (415.91, 266.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2821)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 241, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 749)
[M::mem_pestat] mean and std.dev: (269.78, 137.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 945)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (333, 749, 1187)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2895)
[M::mem_pestat] mean and std.dev: (704.12, 496.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3749)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 260, 407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (252.38, 106.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 938)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696062 sequences (100000265 bp) in 2.651 CPU sec, 2.799 real sec...
[M::process] read 697784 sequences (100000058 bp) in 1.877 CPU sec, 1.878 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 284070, 26, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 595, 1745)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4937)
[M::mem_pestat] mean and std.dev: (894.05, 839.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6533)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 246, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 769)
[M::mem_pestat] mean and std.dev: (275.40, 141.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 971)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 424, 744)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1730)
[M::mem_pestat] mean and std.dev: (416.14, 237.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2223)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 385, 506)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1126)
[M::mem_pestat] mean and std.dev: (311.50, 184.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1436)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697852 reads in 185.198 CPU sec, 6.008 real sec
[M::mem_process_seqs] Processed 696816 reads in 120.879 CPU sec, 3.937 real sec
sorting block 101, #reads = 1076386 mem = 536878256 peak = 1099161600
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 283484, 22, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 287, 628)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1470)
[M::mem_pestat] mean and std.dev: (423.49, 306.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1891)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 250, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 783)
[M::mem_pestat] mean and std.dev: (279.19, 142.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 989)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (616, 880, 1345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2803)
[M::mem_pestat] mean and std.dev: (881.90, 578.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3532)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 321, 724)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1712)
[M::mem_pestat] mean and std.dev: (460.23, 344.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2206)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697298 sequences (100000206 bp) in 2.847 CPU sec, 2.977 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 284550, 31, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 251, 629)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1569)
[M::mem_pestat] mean and std.dev: (387.07, 285.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2039)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 242, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 752)
[M::mem_pestat] mean and std.dev: (270.68, 138.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (359, 1247, 3523)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9851)
[M::mem_pestat] mean and std.dev: (1928.39, 1921.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13015)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (261, 367, 930)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2268)
[M::mem_pestat] mean and std.dev: (547.68, 389.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2937)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697060 sequences (100000252 bp) in 1.970 CPU sec, 1.971 real sec...
[M::mem_process_seqs] Processed 696062 reads in 181.940 CPU sec, 5.863 real sec
[M::mem_process_seqs] Processed 697784 reads in 120.255 CPU sec, 3.795 real sec
sorting block 102, #reads = 1071974 mem = 536881539 peak = 1099161600
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 284148, 20, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 254, 526)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1288)
[M::mem_pestat] mean and std.dev: (323.86, 201.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1669)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 243, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (271.45, 138.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 950)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (100, 301, 1233)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3499)
[M::mem_pestat] mean and std.dev: (477.11, 543.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4632)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 314, 493)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1079)
[M::mem_pestat] mean and std.dev: (322.31, 187.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1372)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697162 sequences (100000205 bp) in 2.576 CPU sec, 2.729 real sec...
[M::process] read 696906 sequences (100000292 bp) in 1.589 CPU sec, 1.593 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 284098, 23, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 269, 538)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1234)
[M::mem_pestat] mean and std.dev: (289.03, 167.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1582)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 244, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 759)
[M::mem_pestat] mean and std.dev: (273.17, 139.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 958)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 528, 2543)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7325)
[M::mem_pestat] mean and std.dev: (1109.86, 1380.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9716)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (341, 362, 1206)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2936)
[M::mem_pestat] mean and std.dev: (626.73, 547.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3801)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697298 reads in 184.654 CPU sec, 5.980 real sec
sorting block 103, #reads = 1075229 mem = 536881591 peak = 1099161600
[M::mem_process_seqs] Processed 697060 reads in 118.899 CPU sec, 3.777 real sec
sorting block 104, #reads = 1075090 mem = 536877810 peak = 1099161600
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 283895, 27, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 350, 1610)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4466)
[M::mem_pestat] mean and std.dev: (925.95, 964.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5894)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 245, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 768)
[M::mem_pestat] mean and std.dev: (274.89, 142.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 970)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 529, 853)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2065)
[M::mem_pestat] mean and std.dev: (416.09, 327.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2671)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 447, 1003)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2535)
[M::mem_pestat] mean and std.dev: (527.50, 388.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3301)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697468 sequences (100000035 bp) in 2.693 CPU sec, 2.852 real sec...
[M::process] read 696932 sequences (100000226 bp) in 1.669 CPU sec, 1.668 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 283389, 22, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 262, 385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 817)
[M::mem_pestat] mean and std.dev: (255.30, 131.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1033)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 244, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (274.12, 140.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 966)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (430, 932, 1234)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2842)
[M::mem_pestat] mean and std.dev: (854.57, 558.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3646)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (333, 440, 818)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1788)
[M::mem_pestat] mean and std.dev: (495.76, 309.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2273)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697162 reads in 188.549 CPU sec, 6.104 real sec
[M::mem_process_seqs] Processed 696906 reads in 125.426 CPU sec, 4.140 real sec
sorting block 105, #reads = 1074073 mem = 536879224 peak = 1099161600
[M::process] read 697174 sequences (100000199 bp) in 2.414 CPU sec, 2.520 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 283852, 24, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (277, 514, 1192)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3022)
[M::mem_pestat] mean and std.dev: (648.65, 598.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3937)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 243, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (273.80, 142.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 966)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 545, 2104)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5850)
[M::mem_pestat] mean and std.dev: (659.71, 758.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7723)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 287, 747)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1823)
[M::mem_pestat] mean and std.dev: (381.20, 252.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2361)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697468 reads in 107.574 CPU sec, 3.601 real sec
sorting block 106, #reads = 1071959 mem = 536878833 peak = 1099161600
[M::process] read 697896 sequences (100000080 bp) in 2.668 CPU sec, 2.839 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 283724, 22, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (255, 481, 723)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1659)
[M::mem_pestat] mean and std.dev: (472.67, 298.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2127)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 243, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 762)
[M::mem_pestat] mean and std.dev: (273.85, 141.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 962)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (448, 978, 3374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9226)
[M::mem_pestat] mean and std.dev: (2013.64, 2363.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12152)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (284, 438, 1399)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3629)
[M::mem_pestat] mean and std.dev: (668.75, 621.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4744)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698648 sequences (100000063 bp) in 1.699 CPU sec, 1.698 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283360, 20, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 255, 664)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1568)
[M::mem_pestat] mean and std.dev: (353.24, 273.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2020)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 242, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (272.19, 140.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 950)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (388, 935, 1704)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4336)
[M::mem_pestat] mean and std.dev: (936.65, 744.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5652)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 429, 505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1055)
[M::mem_pestat] mean and std.dev: (387.75, 176.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1330)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696932 reads in 215.191 CPU sec, 6.868 real sec
[M::mem_process_seqs] Processed 697174 reads in 234.784 CPU sec, 7.521 real sec
sorting block 107, #reads = 1071184 mem = 536879383 peak = 1099161600
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 283647, 17, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 506, 625)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1453)
[M::mem_pestat] mean and std.dev: (385.74, 205.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1867)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 239, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 743)
[M::mem_pestat] mean and std.dev: (269.31, 138.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 937)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (92, 276, 514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1358)
[M::mem_pestat] mean and std.dev: (290.59, 211.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1780)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 317, 747)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1831)
[M::mem_pestat] mean and std.dev: (376.21, 311.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2373)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704388 sequences (100000013 bp) in 2.907 CPU sec, 3.102 real sec...
[M::process] read 701884 sequences (100000220 bp) in 1.889 CPU sec, 1.897 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 283298, 27, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 266, 579)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1387)
[M::mem_pestat] mean and std.dev: (309.85, 231.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1791)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 237, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 735)
[M::mem_pestat] mean and std.dev: (266.23, 137.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 927)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 545, 1389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3783)
[M::mem_pestat] mean and std.dev: (769.48, 768.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4980)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 382, 1441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3911)
[M::mem_pestat] mean and std.dev: (801.75, 813.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5146)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697896 reads in 206.032 CPU sec, 6.566 real sec
[M::mem_process_seqs] Processed 698648 reads in 143.511 CPU sec, 4.572 real sec
sorting block 108, #reads = 1069854 mem = 536878328 peak = 1099161600
[M::process] read 702538 sequences (100000062 bp) in 2.482 CPU sec, 2.596 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 286130, 24, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 286, 1293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3561)
[M::mem_pestat] mean and std.dev: (606.04, 599.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4695)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 225, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 710)
[M::mem_pestat] mean and std.dev: (255.59, 131.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 896)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (69, 171, 743)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2091)
[M::mem_pestat] mean and std.dev: (381.14, 507.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2765)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (297, 996, 1550)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4056)
[M::mem_pestat] mean and std.dev: (1097.89, 979.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5309)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704388 reads in 120.582 CPU sec, 3.861 real sec
sorting block 109, #reads = 1062674 mem = 536878511 peak = 1099161600
[M::process] read 700554 sequences (100000213 bp) in 2.073 CPU sec, 2.171 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 285676, 22, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 479, 1968)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5404)
[M::mem_pestat] mean and std.dev: (1079.24, 1204.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7122)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709)
[M::mem_pestat] mean and std.dev: (256.79, 130.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 894)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (369, 617, 730)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1452)
[M::mem_pestat] mean and std.dev: (537.24, 283.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1813)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 329, 709)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1715)
[M::mem_pestat] mean and std.dev: (379.80, 321.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2218)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700430 sequences (100000033 bp) in 1.784 CPU sec, 1.791 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 285637, 17, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 257, 734)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1814)
[M::mem_pestat] mean and std.dev: (380.00, 375.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2354)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 231, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 731)
[M::mem_pestat] mean and std.dev: (261.47, 134.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 923)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (610, 907, 2088)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5044)
[M::mem_pestat] mean and std.dev: (1420.12, 1323.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6715)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 357, 928)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2410)
[M::mem_pestat] mean and std.dev: (454.22, 357.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3151)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702538 reads in 236.358 CPU sec, 7.562 real sec
[M::mem_process_seqs] Processed 701884 reads in 256.735 CPU sec, 8.348 real sec
sorting block 110, #reads = 1068047 mem = 536879528 peak = 1099161600
[M::process] read 701618 sequences (100000122 bp) in 2.427 CPU sec, 2.536 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 285003, 17, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 259, 485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1163)
[M::mem_pestat] mean and std.dev: (277.76, 229.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1502)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 236, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 745)
[M::mem_pestat] mean and std.dev: (265.27, 135.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 941)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (92, 296, 1388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3980)
[M::mem_pestat] mean and std.dev: (757.12, 830.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5276)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 382, 974)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2484)
[M::mem_pestat] mean and std.dev: (484.44, 333.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3239)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700554 reads in 112.110 CPU sec, 3.728 real sec
sorting block 111, #reads = 1067018 mem = 536878730 peak = 1099161600
[M::process] read 702600 sequences (100000004 bp) in 2.440 CPU sec, 2.727 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 285458, 22, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 275, 646)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1544)
[M::mem_pestat] mean and std.dev: (431.41, 343.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1993)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 236, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (266.85, 137.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 456, 816)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2160)
[M::mem_pestat] mean and std.dev: (645.05, 685.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3385)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 177, 896)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2380)
[M::mem_pestat] mean and std.dev: (499.87, 570.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3122)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701762 sequences (100000023 bp) in 1.520 CPU sec, 1.529 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 285608, 22, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 216, 592)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1426)
[M::mem_pestat] mean and std.dev: (319.96, 238.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1843)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 230, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 722)
[M::mem_pestat] mean and std.dev: (260.59, 134.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 911)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (72, 355, 803)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2265)
[M::mem_pestat] mean and std.dev: (486.82, 473.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2996)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 337, 979)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2577)
[M::mem_pestat] mean and std.dev: (512.70, 359.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3376)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700430 reads in 216.687 CPU sec, 6.928 real sec
[M::mem_process_seqs] Processed 701618 reads in 235.020 CPU sec, 7.639 real sec
sorting block 112, #reads = 1070846 mem = 536877666 peak = 1099161600
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 286138, 18, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 274, 791)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1993)
[M::mem_pestat] mean and std.dev: (493.82, 490.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2594)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 706)
[M::mem_pestat] mean and std.dev: (256.20, 130.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 890)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (439, 984, 1998)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5116)
[M::mem_pestat] mean and std.dev: (1135.59, 1125.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6675)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (410, 674, 1366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3278)
[M::mem_pestat] mean and std.dev: (871.41, 677.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4234)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700658 sequences (100000292 bp) in 2.528 CPU sec, 2.683 real sec...
[M::process] read 698636 sequences (100000150 bp) in 1.480 CPU sec, 1.487 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 285587, 15, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 366, 1105)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2905)
[M::mem_pestat] mean and std.dev: (455.70, 376.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3805)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 229, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (256.04, 128.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (66, 456, 1670)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4878)
[M::mem_pestat] mean and std.dev: (976.67, 1084.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6482)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (275, 419, 543)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1079)
[M::mem_pestat] mean and std.dev: (362.59, 139.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1347)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702600 reads in 195.590 CPU sec, 6.345 real sec
sorting block 113, #reads = 1072854 mem = 536879987 peak = 1099161600
[M::mem_process_seqs] Processed 701762 reads in 133.051 CPU sec, 4.254 real sec
sorting block 114, #reads = 1070972 mem = 536881035 peak = 1099161600
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 285789, 16, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 347, 759)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1871)
[M::mem_pestat] mean and std.dev: (460.45, 396.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2427)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 233, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 715)
[M::mem_pestat] mean and std.dev: (260.34, 131.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 901)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (86, 1150, 2123)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6197)
[M::mem_pestat] mean and std.dev: (939.43, 1165.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8234)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 489, 573)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1257)
[M::mem_pestat] mean and std.dev: (378.55, 174.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1599)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697790 sequences (100000150 bp) in 2.317 CPU sec, 2.458 real sec...
[M::process] read 699604 sequences (100000087 bp) in 1.570 CPU sec, 1.566 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 284451, 40, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 360, 779)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1877)
[M::mem_pestat] mean and std.dev: (478.57, 335.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2426)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 239, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 745)
[M::mem_pestat] mean and std.dev: (268.07, 136.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 940)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 546, 1412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3856)
[M::mem_pestat] mean and std.dev: (809.33, 768.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5078)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 576, 740)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1786)
[M::mem_pestat] mean and std.dev: (494.83, 308.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2309)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700658 reads in 162.018 CPU sec, 5.156 real sec
[M::mem_process_seqs] Processed 698636 reads in 105.292 CPU sec, 3.635 real sec
sorting block 115, #reads = 1074476 mem = 536882060 peak = 1099161600
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 284427, 21, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (368, 524, 1874)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4886)
[M::mem_pestat] mean and std.dev: (882.04, 931.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6392)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 243, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 749)
[M::mem_pestat] mean and std.dev: (270.15, 136.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 945)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (60, 622, 1768)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5184)
[M::mem_pestat] mean and std.dev: (1420.05, 1863.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8874)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 404, 1157)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3049)
[M::mem_pestat] mean and std.dev: (663.72, 640.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3995)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698804 sequences (100000183 bp) in 2.151 CPU sec, 2.258 real sec...
[M::process] read 698306 sequences (100000197 bp) in 1.617 CPU sec, 1.621 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 284852, 18, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 425, 1102)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2900)
[M::mem_pestat] mean and std.dev: (715.71, 697.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3799)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 236, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 731)
[M::mem_pestat] mean and std.dev: (264.63, 134.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 922)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 715, 1269)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3393)
[M::mem_pestat] mean and std.dev: (750.33, 594.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4455)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (270, 792, 2030)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5550)
[M::mem_pestat] mean and std.dev: (1219.21, 1149.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7310)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697790 reads in 168.843 CPU sec, 5.658 real sec
[M::mem_process_seqs] Processed 699604 reads in 113.376 CPU sec, 3.729 real sec
sorting block 116, #reads = 1071703 mem = 536883626 peak = 1099161600
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 284913, 25, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 374, 997)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2567)
[M::mem_pestat] mean and std.dev: (503.15, 448.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3352)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 239, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 739)
[M::mem_pestat] mean and std.dev: (267.13, 135.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 932)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (77, 591, 1384)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3998)
[M::mem_pestat] mean and std.dev: (717.58, 755.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5305)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 303, 750)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1864)
[M::mem_pestat] mean and std.dev: (412.37, 341.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2421)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698728 sequences (100000277 bp) in 2.434 CPU sec, 2.579 real sec...
[M::process] read 697974 sequences (100000164 bp) in 1.820 CPU sec, 1.818 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 284516, 24, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 300, 1296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3520)
[M::mem_pestat] mean and std.dev: (795.73, 762.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4632)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 240, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 742)
[M::mem_pestat] mean and std.dev: (268.14, 135.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 936)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (48, 678, 1883)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5553)
[M::mem_pestat] mean and std.dev: (634.48, 721.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7388)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (275, 382, 2152)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5906)
[M::mem_pestat] mean and std.dev: (1333.56, 1513.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7783)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698804 reads in 175.517 CPU sec, 5.676 real sec
sorting block 117, #reads = 1074204 mem = 536880968 peak = 1099161600
[M::mem_process_seqs] Processed 698306 reads in 111.794 CPU sec, 3.649 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 284495, 23, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 241, 494)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1090)
[M::mem_pestat] mean and std.dev: (245.91, 107.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1388)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 239, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 736)
[M::mem_pestat] mean and std.dev: (266.81, 135.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 928)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 360, 945)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2513)
[M::mem_pestat] mean and std.dev: (557.09, 566.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3297)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (306, 433, 645)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1323)
[M::mem_pestat] mean and std.dev: (407.46, 169.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1662)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697882 sequences (100000258 bp) in 2.700 CPU sec, 2.856 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 284147, 16, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 399, 3052)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8754)
[M::mem_pestat] mean and std.dev: (1514.81, 2005.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11605)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 241, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 749)
[M::mem_pestat] mean and std.dev: (270.65, 138.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 945)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (374, 508, 609)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1079)
[M::mem_pestat] mean and std.dev: (421.20, 193.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1314)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 413, 1022)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2554)
[M::mem_pestat] mean and std.dev: (545.80, 490.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3320)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697468 sequences (100000297 bp) in 1.820 CPU sec, 1.820 real sec...
[M::mem_process_seqs] Processed 698728 reads in 175.908 CPU sec, 5.692 real sec
sorting block 118, #reads = 1072688 mem = 536878518 peak = 1099161600
[M::mem_process_seqs] Processed 697974 reads in 113.401 CPU sec, 3.695 real sec
sorting block 119, #reads = 1074013 mem = 536881883 peak = 1108877312
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 284085, 26, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 287, 552)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1288)
[M::mem_pestat] mean and std.dev: (406.39, 294.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1656)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 241, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 743)
[M::mem_pestat] mean and std.dev: (269.30, 136.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 937)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (452, 1350, 1558)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3770)
[M::mem_pestat] mean and std.dev: (1102.92, 680.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4876)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (284, 848, 3055)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8597)
[M::mem_pestat] mean and std.dev: (1656.08, 1959.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11368)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697256 sequences (100000193 bp) in 2.510 CPU sec, 2.626 real sec...
[M::process] read 697392 sequences (100000087 bp) in 1.570 CPU sec, 1.571 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 284072, 24, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (297, 1303, 2592)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7182)
[M::mem_pestat] mean and std.dev: (1677.89, 1555.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9477)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 242, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 747)
[M::mem_pestat] mean and std.dev: (270.86, 138.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 942)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 373, 609)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1551)
[M::mem_pestat] mean and std.dev: (299.05, 306.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2022)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 339, 822)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2018)
[M::mem_pestat] mean and std.dev: (427.20, 324.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2616)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697882 reads in 178.151 CPU sec, 5.764 real sec
[M::mem_process_seqs] Processed 697468 reads in 113.461 CPU sec, 3.698 real sec
sorting block 120, #reads = 1073639 mem = 536886832 peak = 1108877312
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 284001, 25, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 503, 1592)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4282)
[M::mem_pestat] mean and std.dev: (943.72, 1034.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5627)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 242, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (271.68, 139.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 946)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (679, 884, 1842)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4168)
[M::mem_pestat] mean and std.dev: (997.86, 695.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5331)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 343, 1150)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3064)
[M::mem_pestat] mean and std.dev: (456.59, 399.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4021)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697060 sequences (100000104 bp) in 2.219 CPU sec, 2.326 real sec...
[M::process] read 281834 sequences (40307538 bp) in 0.918 CPU sec, 0.920 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 284235, 26, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 319, 1171)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3109)
[M::mem_pestat] mean and std.dev: (673.29, 775.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4078)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 241, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (271.13, 139.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 946)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (249, 539, 991)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2475)
[M::mem_pestat] mean and std.dev: (565.70, 471.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3217)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 282, 672)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1658)
[M::mem_pestat] mean and std.dev: (338.68, 232.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2151)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697256 reads in 172.246 CPU sec, 5.603 real sec
[M::mem_process_seqs] Processed 697392 reads in 115.740 CPU sec, 3.810 real sec
sorting block 121, #reads = 1073959 mem = 536882739 peak = 1108877312
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 283762, 31, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (275, 834, 1688)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4514)
[M::mem_pestat] mean and std.dev: (1286.55, 1261.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6332)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 242, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (272.03, 139.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 950)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (291, 654, 1605)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4233)
[M::mem_pestat] mean and std.dev: (1052.26, 942.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5547)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (300, 443, 626)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1278)
[M::mem_pestat] mean and std.dev: (454.84, 253.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1604)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (16, 114422, 9, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 441, 634)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1490)
[M::mem_pestat] mean and std.dev: (327.08, 164.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1918)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 725)
[M::mem_pestat] mean and std.dev: (264.15, 135.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 914)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 424, 2272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6378)
[M::mem_pestat] mean and std.dev: (1227.18, 1315.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8431)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697060 reads in 133.204 CPU sec, 4.418 real sec
[M::mem_process_seqs] Processed 281834 reads in 62.055 CPU sec, 2.004 real sec
sorting block 122, #reads = 1073275 mem = 536878847 peak = 1143975936
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 131921650
overall: 70132006912 mem 20061.401 user 508.607 sys 681.056 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1136_4GR-T1-TDNA-1_A23MHWWLT4_1.L008\tPU:L008\tSM:1136_4GR-T1-TDNA-1_A23MHWWLT4_1\tLB:1136_4GR-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1136_4GR-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1136_4GR-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 681.095 sec; CPU: 20570.011 sec
sorting block 123, #reads = 860888 mem = 431783333 peak = 1184116736
uniq header count 1
merging 124 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31 max 192
algo: util-sort
license: sentieon:util=1
output file size: 7460562638
output reads: 133019855
bam_mem_sort: 124 calls 67.912 user 2.389 sys 70.651 real
bam_write: 124 calls 31.020 user 2.695 sys 34.524 real
execute: 1 calls 34.779 user 1.514 sys 724.635 real
merge_files: 1 calls 34.744 user 1.497 sys 42.756 real
parse_chunk: 1981 calls 80.808 user 21.023 sys 103.741 real
read_chunk: 5357 calls 42.488 user 47.810 sys 629.530 real
sort_block: 1 calls 29.649 user 47.390 sys 610.650 real
write_chunk: 3374 calls 34.363 user 1.208 sys 41.801 real
overall: 3439841280 mem 1694.767 user 89.269 sys 724.659 real
ls: cannot access '*.cram': No such file or directory