cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1136_4GR-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 1917.811 CPU sec, 69.285 real sec
[M::process] read 699054 sequences (100000067 bp) in 0.998 CPU sec, 1.003 real sec...
[M::process] read 698038 sequences (100000105 bp) in 1.282 CPU sec, 1.342 real sec...
[M::process] read 696756 sequences (100000009 bp) in 1.248 CPU sec, 1.264 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 283831, 24, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (321, 943, 2111)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5691)
[M::mem_pestat] mean and std.dev: (1054.92, 881.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7481)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 240, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 739)
[M::mem_pestat] mean and std.dev: (267.62, 136.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 932)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 444, 734)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1898)
[M::mem_pestat] mean and std.dev: (365.05, 283.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2480)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 392, 1223)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3211)
[M::mem_pestat] mean and std.dev: (751.55, 774.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4205)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696320 sequences (100000152 bp) in 1.389 CPU sec, 1.384 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 284058, 15, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (285, 406, 1410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3660)
[M::mem_pestat] mean and std.dev: (575.76, 467.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4785)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 243, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (271.61, 138.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (58, 284, 512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1420)
[M::mem_pestat] mean and std.dev: (321.13, 275.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1874)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 490, 569)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1303)
[M::mem_pestat] mean and std.dev: (380.08, 194.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1670)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 284108, 22, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 315, 946)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2542)
[M::mem_pestat] mean and std.dev: (503.88, 456.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3340)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 247, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 772)
[M::mem_pestat] mean and std.dev: (275.62, 141.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 975)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (82, 212, 494)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1318)
[M::mem_pestat] mean and std.dev: (297.05, 317.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1730)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 220, 545)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1247)
[M::mem_pestat] mean and std.dev: (377.30, 256.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1598)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699054 reads in 266.147 CPU sec, 8.518 real sec
[M::mem_process_seqs] Processed 698038 reads in 179.904 CPU sec, 5.792 real sec
[M::mem_process_seqs] Processed 696756 reads in 197.341 CPU sec, 6.358 real sec
sorting block 0, #reads = 1077430 mem = 536877970 peak = 597622784
[M::process] read 696304 sequences (100000294 bp) in 2.104 CPU sec, 2.244 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 283460, 29, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 501, 663)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1659)
[M::mem_pestat] mean and std.dev: (411.24, 304.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2157)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 250, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 779)
[M::mem_pestat] mean and std.dev: (277.93, 142.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 984)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 356, 823)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2145)
[M::mem_pestat] mean and std.dev: (446.00, 375.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2806)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 247, 424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 894)
[M::mem_pestat] mean and std.dev: (319.58, 191.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1129)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695474 sequences (100000232 bp) in 1.770 CPU sec, 1.793 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 283657, 27, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 182, 424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 992)
[M::mem_pestat] mean and std.dev: (199.71, 95.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1276)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 251, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 780)
[M::mem_pestat] mean and std.dev: (278.70, 142.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 985)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 264, 1093)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2751)
[M::mem_pestat] mean and std.dev: (622.33, 677.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3580)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 441, 1010)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2546)
[M::mem_pestat] mean and std.dev: (605.90, 507.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3314)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696320 reads in 160.532 CPU sec, 5.076 real sec
[M::process] read 695318 sequences (100000130 bp) in 1.644 CPU sec, 1.655 real sec...
sorting block 1, #reads = 1075595 mem = 536879265 peak = 784793600
[M::mem_process_seqs] Processed 696304 reads in 107.061 CPU sec, 3.382 real sec
sorting block 2, #reads = 1076288 mem = 536880835 peak = 881782784
[M::process] read 695190 sequences (100000125 bp) in 1.951 CPU sec, 2.046 real sec...
[M::process] read 696292 sequences (100000082 bp) in 1.704 CPU sec, 1.706 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 283417, 21, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 282, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 937)
[M::mem_pestat] mean and std.dev: (307.55, 159.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1171)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 255, 375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 793)
[M::mem_pestat] mean and std.dev: (282.52, 144.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1002)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (65, 382, 1471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4283)
[M::mem_pestat] mean and std.dev: (676.48, 818.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5689)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 354, 764)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1832)
[M::mem_pestat] mean and std.dev: (498.17, 373.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2366)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695318 reads in 84.325 CPU sec, 2.699 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 283075, 24, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (305, 422, 693)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1469)
[M::mem_pestat] mean and std.dev: (417.42, 277.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1857)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 252, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 781)
[M::mem_pestat] mean and std.dev: (279.74, 142.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 986)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (454, 1061, 2055)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5257)
[M::mem_pestat] mean and std.dev: (1027.55, 952.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6858)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 320, 1252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3352)
[M::mem_pestat] mean and std.dev: (689.48, 645.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4402)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 282610, 35, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (367, 501, 1551)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3919)
[M::mem_pestat] mean and std.dev: (672.23, 598.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5103)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 256, 380)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 804)
[M::mem_pestat] mean and std.dev: (285.31, 146.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1016)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (281, 865, 1523)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4007)
[M::mem_pestat] mean and std.dev: (868.91, 621.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5249)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 361, 979)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2565)
[M::mem_pestat] mean and std.dev: (505.31, 499.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3358)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696360 sequences (100000014 bp) in 1.791 CPU sec, 1.797 real sec...
[M::mem_process_seqs] Processed 695474 reads in 246.905 CPU sec, 7.873 real sec
sorting block 3, #reads = 1077484 mem = 536885319 peak = 881782784
[M::mem_process_seqs] Processed 695190 reads in 123.233 CPU sec, 4.032 real sec
sorting block 4, #reads = 1077204 mem = 536878481 peak = 895361024
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 283437, 24, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 304, 918)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2412)
[M::mem_pestat] mean and std.dev: (638.00, 625.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3159)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 250, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 785)
[M::mem_pestat] mean and std.dev: (279.11, 143.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 992)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (365, 1009, 1421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3533)
[M::mem_pestat] mean and std.dev: (798.95, 670.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4589)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (288, 455, 929)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2211)
[M::mem_pestat] mean and std.dev: (655.92, 453.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2852)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695862 sequences (100000056 bp) in 2.208 CPU sec, 2.350 real sec...
[M::process] read 695792 sequences (100000030 bp) in 1.720 CPU sec, 1.715 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 283508, 11, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (283, 463, 1057)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2605)
[M::mem_pestat] mean and std.dev: (584.82, 401.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3379)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 250, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 780)
[M::mem_pestat] mean and std.dev: (278.86, 143.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 985)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (301, 462, 1405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3613)
[M::mem_pestat] mean and std.dev: (645.36, 524.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4717)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 343, 958)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2402)
[M::mem_pestat] mean and std.dev: (574.58, 515.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3124)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696292 reads in 166.404 CPU sec, 5.352 real sec
[M::mem_process_seqs] Processed 696360 reads in 107.968 CPU sec, 3.429 real sec
sorting block 5, #reads = 1077227 mem = 536881862 peak = 895361024
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 283025, 25, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 524, 880)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2196)
[M::mem_pestat] mean and std.dev: (542.52, 358.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2854)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 252, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 781)
[M::mem_pestat] mean and std.dev: (280.20, 143.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 986)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 920, 1324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3486)
[M::mem_pestat] mean and std.dev: (815.00, 630.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4567)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 375, 928)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2352)
[M::mem_pestat] mean and std.dev: (593.50, 547.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3064)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695682 sequences (100000059 bp) in 2.053 CPU sec, 2.188 real sec...
[M::process] read 695018 sequences (100000067 bp) in 1.314 CPU sec, 1.315 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 282823, 20, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 364, 531)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1159)
[M::mem_pestat] mean and std.dev: (371.13, 187.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1473)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 251, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 780)
[M::mem_pestat] mean and std.dev: (279.23, 142.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 985)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 257, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1023)
[M::mem_pestat] mean and std.dev: (251.83, 178.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1315)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 347, 591)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1483)
[M::mem_pestat] mean and std.dev: (327.05, 222.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1929)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695862 reads in 162.232 CPU sec, 5.244 real sec
[M::mem_process_seqs] Processed 695792 reads in 104.426 CPU sec, 3.405 real sec
sorting block 6, #reads = 1077233 mem = 536878636 peak = 895361024
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 283312, 24, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 417, 1235)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3217)
[M::mem_pestat] mean and std.dev: (480.71, 370.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4208)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 251, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 775)
[M::mem_pestat] mean and std.dev: (278.87, 142.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 978)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (128, 566, 2443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7073)
[M::mem_pestat] mean and std.dev: (1061.71, 1335.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9388)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (274, 517, 1139)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2869)
[M::mem_pestat] mean and std.dev: (513.39, 320.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3734)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694974 sequences (100000222 bp) in 2.473 CPU sec, 2.652 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 282760, 16, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 297, 673)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1691)
[M::mem_pestat] mean and std.dev: (346.40, 319.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2200)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 252, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (279.14, 141.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 975)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (96, 388, 1427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4089)
[M::mem_pestat] mean and std.dev: (509.73, 578.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5420)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 377, 852)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2190)
[M::mem_pestat] mean and std.dev: (487.98, 451.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2859)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695388 sequences (100000041 bp) in 1.760 CPU sec, 1.769 real sec...
[M::mem_process_seqs] Processed 695682 reads in 163.466 CPU sec, 5.263 real sec
sorting block 7, #reads = 1076837 mem = 536880949 peak = 895361024
[M::mem_process_seqs] Processed 695018 reads in 107.645 CPU sec, 3.481 real sec
sorting block 8, #reads = 1076337 mem = 536876577 peak = 895361024
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 283036, 18, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 290, 578)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1338)
[M::mem_pestat] mean and std.dev: (350.48, 243.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1718)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 251, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 767)
[M::mem_pestat] mean and std.dev: (277.94, 139.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 967)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (132, 427, 1284)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3588)
[M::mem_pestat] mean and std.dev: (590.88, 551.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4740)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 418, 603)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1381)
[M::mem_pestat] mean and std.dev: (375.48, 239.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1770)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697778 sequences (100000237 bp) in 2.451 CPU sec, 2.579 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 282998, 18, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 312, 622)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1506)
[M::mem_pestat] mean and std.dev: (421.00, 323.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1948)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 249, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (275.13, 137.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 950)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 535, 915)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2323)
[M::mem_pestat] mean and std.dev: (683.35, 562.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3027)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 274, 601)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1409)
[M::mem_pestat] mean and std.dev: (362.72, 251.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1813)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695144 sequences (100000253 bp) in 1.800 CPU sec, 1.796 real sec...
[M::mem_process_seqs] Processed 694974 reads in 166.905 CPU sec, 5.375 real sec
[M::mem_process_seqs] Processed 695388 reads in 112.799 CPU sec, 3.579 real sec
sorting block 9, #reads = 1076910 mem = 536881538 peak = 895361024
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 283269, 25, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 233, 802)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2122)
[M::mem_pestat] mean and std.dev: (386.79, 436.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2782)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 243, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 735)
[M::mem_pestat] mean and std.dev: (267.86, 133.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 926)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 346, 1326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3630)
[M::mem_pestat] mean and std.dev: (609.12, 619.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4782)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (272, 356, 717)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1607)
[M::mem_pestat] mean and std.dev: (505.28, 379.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2052)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694868 sequences (100000218 bp) in 2.418 CPU sec, 2.576 real sec...
[M::process] read 694976 sequences (100000067 bp) in 1.780 CPU sec, 1.777 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 282499, 22, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 436, 1096)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2746)
[M::mem_pestat] mean and std.dev: (534.64, 456.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3571)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 249, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (274.54, 137.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 946)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 1395, 5953)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 17461)
[M::mem_pestat] mean and std.dev: (2523.68, 2565.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 23215)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 337, 1011)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2611)
[M::mem_pestat] mean and std.dev: (473.83, 433.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3411)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697778 reads in 168.568 CPU sec, 5.343 real sec
[M::mem_process_seqs] Processed 695144 reads in 108.018 CPU sec, 3.441 real sec
sorting block 10, #reads = 1072131 mem = 536881169 peak = 895361024
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 282358, 29, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 413, 655)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1597)
[M::mem_pestat] mean and std.dev: (397.81, 259.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2068)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 250, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (275.31, 137.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 950)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (321, 731, 1785)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4713)
[M::mem_pestat] mean and std.dev: (891.26, 823.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6177)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 445, 2433)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6947)
[M::mem_pestat] mean and std.dev: (1065.64, 1080.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9204)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694838 sequences (100000222 bp) in 2.406 CPU sec, 2.550 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 283064, 23, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 298, 1057)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2773)
[M::mem_pestat] mean and std.dev: (712.33, 701.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3631)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 249, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (274.91, 137.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 950)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (277, 391, 1333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3445)
[M::mem_pestat] mean and std.dev: (830.57, 717.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4501)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (415, 789, 1310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3100)
[M::mem_pestat] mean and std.dev: (882.56, 696.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3995)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694316 sequences (100000231 bp) in 1.760 CPU sec, 1.763 real sec...
[M::mem_process_seqs] Processed 694868 reads in 166.213 CPU sec, 5.290 real sec
sorting block 11, #reads = 1074090 mem = 536877899 peak = 895361024
[M::mem_process_seqs] Processed 694976 reads in 108.265 CPU sec, 3.423 real sec
sorting block 12, #reads = 1074785 mem = 536878811 peak = 895361024
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 282334, 24, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 392, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1003)
[M::mem_pestat] mean and std.dev: (333.43, 192.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1269)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 250, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (275.75, 137.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 951)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (80, 576, 1695)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4925)
[M::mem_pestat] mean and std.dev: (830.86, 1065.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6540)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 256, 1254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3324)
[M::mem_pestat] mean and std.dev: (586.44, 750.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4359)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694198 sequences (100000133 bp) in 2.495 CPU sec, 2.640 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 283170, 26, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 283, 880)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2264)
[M::mem_pestat] mean and std.dev: (497.52, 499.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2956)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 252, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 762)
[M::mem_pestat] mean and std.dev: (278.05, 139.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 960)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (128, 654, 1464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4136)
[M::mem_pestat] mean and std.dev: (905.15, 900.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5472)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (323, 689, 2008)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5378)
[M::mem_pestat] mean and std.dev: (1044.00, 847.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7063)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694036 sequences (100000035 bp) in 1.710 CPU sec, 1.712 real sec...
[M::mem_process_seqs] Processed 694838 reads in 169.234 CPU sec, 5.415 real sec
[M::mem_process_seqs] Processed 694316 reads in 110.389 CPU sec, 3.497 real sec
sorting block 13, #reads = 1075323 mem = 536879555 peak = 895361024
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 282496, 38, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 322, 1230)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3388)
[M::mem_pestat] mean and std.dev: (605.00, 630.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4467)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 252, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 759)
[M::mem_pestat] mean and std.dev: (277.54, 138.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 956)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (274, 845, 1771)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4765)
[M::mem_pestat] mean and std.dev: (1232.61, 1186.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6262)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (308, 621, 1088)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2648)
[M::mem_pestat] mean and std.dev: (522.68, 299.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3428)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693982 sequences (100000133 bp) in 2.680 CPU sec, 2.838 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 282188, 34, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 844, 1277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3433)
[M::mem_pestat] mean and std.dev: (712.92, 577.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4511)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 253, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 762)
[M::mem_pestat] mean and std.dev: (278.02, 138.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 960)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (484, 1175, 3419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9289)
[M::mem_pestat] mean and std.dev: (2100.74, 2280.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12224)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 489, 951)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2421)
[M::mem_pestat] mean and std.dev: (498.07, 336.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3156)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696950 sequences (100000179 bp) in 1.810 CPU sec, 1.818 real sec...
[M::mem_process_seqs] Processed 694198 reads in 164.370 CPU sec, 5.216 real sec
[M::mem_process_seqs] Processed 694036 reads in 119.043 CPU sec, 3.783 real sec
sorting block 14, #reads = 1074640 mem = 536879836 peak = 895361024
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 282626, 23, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 295, 566)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1256)
[M::mem_pestat] mean and std.dev: (391.09, 285.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1601)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 253, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (278.55, 138.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 961)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (66, 763, 2588)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7632)
[M::mem_pestat] mean and std.dev: (1334.96, 1676.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10154)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 411, 1219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3145)
[M::mem_pestat] mean and std.dev: (699.78, 591.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4108)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696854 sequences (100000234 bp) in 2.574 CPU sec, 2.742 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 283702, 15, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 347, 695)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1743)
[M::mem_pestat] mean and std.dev: (452.42, 414.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2267)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 246, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (272.52, 137.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 951)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (257, 1057, 3783)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10835)
[M::mem_pestat] mean and std.dev: (1666.93, 1488.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14361)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 380, 1444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3910)
[M::mem_pestat] mean and std.dev: (653.83, 724.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5143)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696622 sequences (100000233 bp) in 1.830 CPU sec, 1.824 real sec...
[M::mem_process_seqs] Processed 693982 reads in 164.540 CPU sec, 5.215 real sec
sorting block 15, #reads = 1075294 mem = 536882017 peak = 895361024
[M::mem_process_seqs] Processed 696950 reads in 109.874 CPU sec, 3.469 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 283759, 18, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (275, 521, 1305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3365)
[M::mem_pestat] mean and std.dev: (836.59, 743.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4395)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 247, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 766)
[M::mem_pestat] mean and std.dev: (274.86, 140.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 967)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (22, 93, 688)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2020)
[M::mem_pestat] mean and std.dev: (380.94, 416.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2686)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 293, 660)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1608)
[M::mem_pestat] mean and std.dev: (393.93, 369.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2082)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696188 sequences (100000136 bp) in 2.576 CPU sec, 2.750 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283796, 21, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 387, 725)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1891)
[M::mem_pestat] mean and std.dev: (476.76, 474.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2474)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 249, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 779)
[M::mem_pestat] mean and std.dev: (277.73, 142.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 984)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (314, 1380, 1679)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4409)
[M::mem_pestat] mean and std.dev: (909.61, 654.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5774)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (423, 456, 1416)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3402)
[M::mem_pestat] mean and std.dev: (741.00, 493.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4395)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695814 sequences (100000254 bp) in 1.770 CPU sec, 1.769 real sec...
[M::mem_process_seqs] Processed 696854 reads in 164.921 CPU sec, 5.390 real sec
sorting block 16, #reads = 1075539 mem = 536884447 peak = 895361024
[M::mem_process_seqs] Processed 696622 reads in 107.466 CPU sec, 3.409 real sec
sorting block 17, #reads = 1078429 mem = 536880378 peak = 963772416
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 283691, 32, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 461, 521)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1227)
[M::mem_pestat] mean and std.dev: (355.05, 226.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1580)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 251, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 786)
[M::mem_pestat] mean and std.dev: (279.66, 143.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 993)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (543, 1538, 1893)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4593)
[M::mem_pestat] mean and std.dev: (1288.97, 872.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5943)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 382, 1695)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4623)
[M::mem_pestat] mean and std.dev: (746.20, 833.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6087)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695442 sequences (100000022 bp) in 2.400 CPU sec, 2.566 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 283654, 10, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (255, 284, 1055)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2655)
[M::mem_pestat] mean and std.dev: (559.21, 523.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3455)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 252, 375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 795)
[M::mem_pestat] mean and std.dev: (281.83, 146.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1005)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (307, 898, 2461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6769)
[M::mem_pestat] mean and std.dev: (1395.40, 1314.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8923)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (303, 676, 2707)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7515)
[M::mem_pestat] mean and std.dev: (1100.78, 1035.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9919)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694724 sequences (100000070 bp) in 1.410 CPU sec, 1.409 real sec...
[M::mem_process_seqs] Processed 696188 reads in 157.972 CPU sec, 5.032 real sec
[M::mem_process_seqs] Processed 695814 reads in 106.289 CPU sec, 3.375 real sec
sorting block 18, #reads = 1078705 mem = 536882403 peak = 963772416
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 283187, 38, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (266, 349, 1337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3479)
[M::mem_pestat] mean and std.dev: (708.26, 662.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4550)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 254, 376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 794)
[M::mem_pestat] mean and std.dev: (282.56, 145.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1003)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (252, 559, 1339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3513)
[M::mem_pestat] mean and std.dev: (863.75, 820.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4600)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 399, 898)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2202)
[M::mem_pestat] mean and std.dev: (546.91, 443.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2854)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694676 sequences (100000204 bp) in 2.480 CPU sec, 2.626 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 283107, 31, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (288, 373, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (4, 714)
[M::mem_pestat] mean and std.dev: (341.70, 128.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 856)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 257, 380)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 804)
[M::mem_pestat] mean and std.dev: (285.19, 146.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1016)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (402, 785, 1296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3084)
[M::mem_pestat] mean and std.dev: (667.15, 527.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3978)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 339, 963)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2485)
[M::mem_pestat] mean and std.dev: (537.93, 383.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3246)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694982 sequences (100000168 bp) in 1.820 CPU sec, 1.826 real sec...
[M::mem_process_seqs] Processed 695442 reads in 158.448 CPU sec, 5.021 real sec
[M::mem_process_seqs] Processed 694724 reads in 104.489 CPU sec, 3.294 real sec
sorting block 19, #reads = 1077552 mem = 536879686 peak = 963772416
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 283107, 33, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 334, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 960)
[M::mem_pestat] mean and std.dev: (320.22, 197.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1225)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 257, 382)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 810)
[M::mem_pestat] mean and std.dev: (286.55, 148.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1024)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (81, 228, 1277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3669)
[M::mem_pestat] mean and std.dev: (880.73, 1114.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5340)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (301, 1411, 3953)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11257)
[M::mem_pestat] mean and std.dev: (2585.59, 2801.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14909)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695930 sequences (100000009 bp) in 2.471 CPU sec, 2.614 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 283630, 17, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 189, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1075)
[M::mem_pestat] mean and std.dev: (243.65, 147.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1381)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 256, 381)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 809)
[M::mem_pestat] mean and std.dev: (285.78, 147.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1023)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (68, 449, 1439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4181)
[M::mem_pestat] mean and std.dev: (782.35, 791.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5552)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 285, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 942)
[M::mem_pestat] mean and std.dev: (297.65, 154.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1186)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695494 sequences (100000291 bp) in 1.830 CPU sec, 1.823 real sec...
[M::mem_process_seqs] Processed 694676 reads in 168.468 CPU sec, 5.430 real sec
sorting block 20, #reads = 1077361 mem = 536880707 peak = 963772416
[M::mem_process_seqs] Processed 694982 reads in 108.592 CPU sec, 3.424 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 283875, 22, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 683, 1483)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4139)
[M::mem_pestat] mean and std.dev: (985.35, 821.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5467)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 251, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 786)
[M::mem_pestat] mean and std.dev: (280.16, 144.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 993)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 557, 1548)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4254)
[M::mem_pestat] mean and std.dev: (726.10, 797.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5607)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 457, 1011)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2637)
[M::mem_pestat] mean and std.dev: (537.19, 457.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3450)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 21, #reads = 1076969 mem = 536878147 peak = 963772416
[M::process] read 695308 sequences (100000112 bp) in 2.516 CPU sec, 2.658 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 283394, 31, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 289, 770)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1906)
[M::mem_pestat] mean and std.dev: (480.93, 379.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2474)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 252, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 787)
[M::mem_pestat] mean and std.dev: (281.03, 144.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 994)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (372, 763, 1807)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4677)
[M::mem_pestat] mean and std.dev: (981.45, 799.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6112)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 399, 641)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1547)
[M::mem_pestat] mean and std.dev: (456.54, 320.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2000)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695144 sequences (100000057 bp) in 1.540 CPU sec, 1.542 real sec...
[M::mem_process_seqs] Processed 695930 reads in 169.080 CPU sec, 5.394 real sec
[M::mem_process_seqs] Processed 695494 reads in 109.697 CPU sec, 3.475 real sec
sorting block 22, #reads = 1077821 mem = 536877721 peak = 963772416
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 283143, 27, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 302, 532)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1252)
[M::mem_pestat] mean and std.dev: (337.32, 231.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1612)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 253, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 782)
[M::mem_pestat] mean and std.dev: (280.72, 143.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 987)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 437, 1094)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2988)
[M::mem_pestat] mean and std.dev: (494.08, 542.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3935)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 516, 939)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2479)
[M::mem_pestat] mean and std.dev: (413.47, 302.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3249)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694930 sequences (100000190 bp) in 2.660 CPU sec, 2.817 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 282789, 36, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 340, 644)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1604)
[M::mem_pestat] mean and std.dev: (406.47, 343.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2084)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 252, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 776)
[M::mem_pestat] mean and std.dev: (279.53, 142.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 979)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 709, 1098)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2806)
[M::mem_pestat] mean and std.dev: (689.09, 652.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3660)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (347, 467, 987)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2267)
[M::mem_pestat] mean and std.dev: (578.64, 479.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2907)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695274 sequences (100000290 bp) in 1.820 CPU sec, 1.820 real sec...
[M::mem_process_seqs] Processed 695308 reads in 162.535 CPU sec, 5.155 real sec
[M::mem_process_seqs] Processed 695144 reads in 106.776 CPU sec, 3.371 real sec
sorting block 23, #reads = 1076516 mem = 536884774 peak = 963772416
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 283521, 28, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 330, 1274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3514)
[M::mem_pestat] mean and std.dev: (649.57, 628.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4634)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 252, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (279.25, 141.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 975)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (67, 177, 1664)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4858)
[M::mem_pestat] mean and std.dev: (750.07, 1112.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6455)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (334, 1159, 2191)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5905)
[M::mem_pestat] mean and std.dev: (1406.04, 1434.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7762)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695800 sequences (100000176 bp) in 2.567 CPU sec, 2.693 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 282645, 34, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 727, 1507)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4039)
[M::mem_pestat] mean and std.dev: (765.97, 733.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5305)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 249, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (276.31, 139.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 962)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (257, 1130, 2670)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7496)
[M::mem_pestat] mean and std.dev: (1223.87, 1261.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9909)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 394, 1577)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4319)
[M::mem_pestat] mean and std.dev: (838.07, 927.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5690)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697970 sequences (100000269 bp) in 1.890 CPU sec, 1.891 real sec...
[M::mem_process_seqs] Processed 694930 reads in 160.303 CPU sec, 5.085 real sec
sorting block 24, #reads = 1075172 mem = 536880707 peak = 963772416
[M::mem_process_seqs] Processed 695274 reads in 107.339 CPU sec, 3.486 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 283618, 33, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 312, 1690)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4720)
[M::mem_pestat] mean and std.dev: (784.52, 989.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6235)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (274.53, 138.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 953)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (510, 930, 1982)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4926)
[M::mem_pestat] mean and std.dev: (1238.75, 951.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6398)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 226, 884)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2314)
[M::mem_pestat] mean and std.dev: (421.52, 418.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3029)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 25, #reads = 1076128 mem = 536879637 peak = 963772416
[M::process] read 696034 sequences (100000211 bp) in 2.573 CPU sec, 2.715 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 283567, 25, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 285, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 932)
[M::mem_pestat] mean and std.dev: (285.49, 133.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1170)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 242, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 743)
[M::mem_pestat] mean and std.dev: (269.24, 136.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 937)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (111, 549, 2111)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6111)
[M::mem_pestat] mean and std.dev: (1096.64, 1238.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8111)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 558, 915)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2273)
[M::mem_pestat] mean and std.dev: (562.65, 442.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2952)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695328 sequences (100000017 bp) in 1.839 CPU sec, 1.834 real sec...
[M::mem_process_seqs] Processed 695800 reads in 173.676 CPU sec, 5.613 real sec
[M::mem_process_seqs] Processed 697970 reads in 119.321 CPU sec, 3.863 real sec
sorting block 26, #reads = 1075585 mem = 536880830 peak = 963772416
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283436, 33, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 332, 750)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1822)
[M::mem_pestat] mean and std.dev: (417.15, 316.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2358)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (274.41, 138.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 953)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 1349, 1445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3863)
[M::mem_pestat] mean and std.dev: (1026.77, 898.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5072)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 452, 1188)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3056)
[M::mem_pestat] mean and std.dev: (656.38, 471.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3990)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695296 sequences (100000050 bp) in 2.540 CPU sec, 2.663 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 282894, 23, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 324, 986)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2638)
[M::mem_pestat] mean and std.dev: (529.80, 536.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3464)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 762)
[M::mem_pestat] mean and std.dev: (275.84, 139.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 961)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (363, 879, 1631)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4167)
[M::mem_pestat] mean and std.dev: (906.77, 740.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5435)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (268, 388, 1007)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2485)
[M::mem_pestat] mean and std.dev: (594.79, 565.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3224)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694920 sequences (100000115 bp) in 1.850 CPU sec, 1.855 real sec...
[M::mem_process_seqs] Processed 696034 reads in 167.929 CPU sec, 5.392 real sec
[M::mem_process_seqs] Processed 695328 reads in 108.209 CPU sec, 3.419 real sec
sorting block 27, #reads = 1072262 mem = 536880159 peak = 963772416
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 282512, 30, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 322, 920)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2344)
[M::mem_pestat] mean and std.dev: (512.10, 518.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3056)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 249, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (275.70, 139.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 958)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (355, 643, 1247)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3031)
[M::mem_pestat] mean and std.dev: (726.78, 612.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3923)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (318, 682, 1104)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2676)
[M::mem_pestat] mean and std.dev: (689.03, 499.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3462)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694766 sequences (100000163 bp) in 2.380 CPU sec, 2.688 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 282841, 29, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 350, 477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1101)
[M::mem_pestat] mean and std.dev: (263.10, 148.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1413)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 251, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (276.70, 139.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 959)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 360, 2356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6600)
[M::mem_pestat] mean and std.dev: (978.04, 1187.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8722)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (295, 426, 653)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1369)
[M::mem_pestat] mean and std.dev: (461.90, 230.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1727)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694306 sequences (100000272 bp) in 1.820 CPU sec, 1.821 real sec...
[M::mem_process_seqs] Processed 695296 reads in 159.671 CPU sec, 5.061 real sec
[M::mem_process_seqs] Processed 694920 reads in 107.029 CPU sec, 3.376 real sec
sorting block 28, #reads = 1074800 mem = 536881350 peak = 963772416
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 283241, 34, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (259, 354, 585)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1237)
[M::mem_pestat] mean and std.dev: (369.12, 203.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1563)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 251, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (276.77, 138.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 955)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (69, 1263, 2376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6990)
[M::mem_pestat] mean and std.dev: (1502.47, 1711.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9297)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 283, 508)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1166)
[M::mem_pestat] mean and std.dev: (326.70, 180.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1495)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694632 sequences (100000234 bp) in 2.400 CPU sec, 2.531 real sec...
[M::process] read 694188 sequences (100000275 bp) in 1.750 CPU sec, 1.755 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 282497, 21, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 329, 508)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1068)
[M::mem_pestat] mean and std.dev: (336.30, 205.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1348)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 253, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 762)
[M::mem_pestat] mean and std.dev: (277.90, 138.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 960)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (431, 597, 3265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8933)
[M::mem_pestat] mean and std.dev: (1609.95, 2134.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11767)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 302, 636)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1484)
[M::mem_pestat] mean and std.dev: (397.65, 314.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1908)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694766 reads in 162.863 CPU sec, 5.221 real sec
sorting block 29, #reads = 1075427 mem = 536879886 peak = 963772416
[M::mem_process_seqs] Processed 694306 reads in 110.263 CPU sec, 3.492 real sec
sorting block 30, #reads = 1075031 mem = 536879546 peak = 969093120
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (16, 282720, 17, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (432, 2226, 3877)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10767)
[M::mem_pestat] mean and std.dev: (1948.56, 1606.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14212)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 253, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (279.03, 140.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 975)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (57, 148, 1466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4284)
[M::mem_pestat] mean and std.dev: (615.24, 628.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5693)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 285, 500)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1080)
[M::mem_pestat] mean and std.dev: (311.45, 142.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1370)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697396 sequences (100000149 bp) in 2.532 CPU sec, 2.658 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 282935, 22, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 263, 763)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1909)
[M::mem_pestat] mean and std.dev: (351.53, 284.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2482)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 254, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 771)
[M::mem_pestat] mean and std.dev: (279.87, 140.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 972)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (102, 776, 1658)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4770)
[M::mem_pestat] mean and std.dev: (904.14, 828.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6326)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (300, 430, 1374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3522)
[M::mem_pestat] mean and std.dev: (734.30, 683.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4596)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697742 sequences (100000227 bp) in 1.830 CPU sec, 1.828 real sec...
[M::mem_process_seqs] Processed 694632 reads in 168.301 CPU sec, 5.457 real sec
[M::mem_process_seqs] Processed 694188 reads in 107.902 CPU sec, 3.500 real sec
sorting block 31, #reads = 1074421 mem = 536879523 peak = 969093120
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 283873, 23, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 364, 661)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1605)
[M::mem_pestat] mean and std.dev: (434.82, 366.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2077)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 245, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (273.19, 139.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 959)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 563, 1192)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3244)
[M::mem_pestat] mean and std.dev: (498.86, 449.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4270)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (300, 754, 1492)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3876)
[M::mem_pestat] mean and std.dev: (988.33, 926.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5068)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696700 sequences (100000044 bp) in 2.588 CPU sec, 2.725 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 283752, 9, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (355, 450, 1084)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2542)
[M::mem_pestat] mean and std.dev: (611.27, 469.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3271)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 245, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 762)
[M::mem_pestat] mean and std.dev: (273.39, 140.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 962)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 197, 696)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1804)
[M::mem_pestat] mean and std.dev: (339.73, 370.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2358)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 695736 sequences (100000275 bp) in 1.820 CPU sec, 1.823 real sec...
[M::mem_process_seqs] Processed 697396 reads in 165.665 CPU sec, 5.354 real sec
[M::mem_process_seqs] Processed 697742 reads in 109.467 CPU sec, 3.469 real sec
sorting block 32, #reads = 1075717 mem = 536881664 peak = 969093120
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 284246, 24, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 297, 815)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2097)
[M::mem_pestat] mean and std.dev: (504.83, 442.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2738)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 249, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (276.91, 142.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 976)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 562, 980)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2608)
[M::mem_pestat] mean and std.dev: (636.58, 609.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3422)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (294, 542, 1498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3906)
[M::mem_pestat] mean and std.dev: (829.38, 787.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5110)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695160 sequences (100000100 bp) in 2.540 CPU sec, 2.682 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 282950, 24, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (325, 535, 1326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3328)
[M::mem_pestat] mean and std.dev: (804.89, 720.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4329)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 252, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 781)
[M::mem_pestat] mean and std.dev: (279.61, 142.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 986)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (323, 438, 1054)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2516)
[M::mem_pestat] mean and std.dev: (535.25, 403.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3247)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 328, 474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1022)
[M::mem_pestat] mean and std.dev: (342.02, 203.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1296)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694732 sequences (100000274 bp) in 1.810 CPU sec, 1.811 real sec...
[M::mem_process_seqs] Processed 696700 reads in 159.325 CPU sec, 5.058 real sec
sorting block 33, #reads = 1076914 mem = 536879922 peak = 969093120
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 283300, 11, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (301, 529, 1047)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2539)
[M::mem_pestat] mean and std.dev: (604.37, 373.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3285)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 254, 375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 791)
[M::mem_pestat] mean and std.dev: (282.27, 144.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 999)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (60, 134, 136)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 288)
[M::mem_pestat] mean and std.dev: (81.33, 53.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 364)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 292, 420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 862)
[M::mem_pestat] mean and std.dev: (332.33, 186.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1083)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694194 sequences (100000123 bp) in 1.925 CPU sec, 1.928 real sec...
[M::mem_process_seqs] Processed 695160 reads in 93.044 CPU sec, 3.009 real sec
sorting block 34, #reads = 1076573 mem = 536879232 peak = 969093120
[M::mem_process_seqs] Processed 695736 reads in 228.702 CPU sec, 7.312 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 283074, 22, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 383, 1117)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2975)
[M::mem_pestat] mean and std.dev: (603.30, 662.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3904)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 257, 379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 801)
[M::mem_pestat] mean and std.dev: (285.22, 146.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1012)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (340, 526, 1705)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4435)
[M::mem_pestat] mean and std.dev: (570.06, 479.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5800)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 368, 1215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3147)
[M::mem_pestat] mean and std.dev: (832.67, 863.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4287)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694224 sequences (100000037 bp) in 2.547 CPU sec, 2.903 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 283151, 25, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 207, 1104)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3046)
[M::mem_pestat] mean and std.dev: (593.14, 740.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4017)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 259, 382)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 808)
[M::mem_pestat] mean and std.dev: (287.10, 147.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1021)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (508, 1060, 1985)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4939)
[M::mem_pestat] mean and std.dev: (1465.52, 1080.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6416)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 525, 1148)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2956)
[M::mem_pestat] mean and std.dev: (550.17, 489.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3860)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694732 reads in 176.114 CPU sec, 5.596 real sec
sorting block 35, #reads = 1076519 mem = 536885505 peak = 969093120
[M::mem_process_seqs] Processed 694194 reads in 107.855 CPU sec, 3.422 real sec
[M::process] read 694504 sequences (100000206 bp) in 2.168 CPU sec, 2.277 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 282983, 28, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 301, 1086)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2938)
[M::mem_pestat] mean and std.dev: (738.90, 832.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4067)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 259, 386)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 820)
[M::mem_pestat] mean and std.dev: (289.14, 150.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1037)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (45, 313, 654)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1872)
[M::mem_pestat] mean and std.dev: (290.25, 390.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2481)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 278, 796)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1944)
[M::mem_pestat] mean and std.dev: (364.62, 289.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2518)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 36, #reads = 1075045 mem = 536878546 peak = 978354176
[M::process] read 696038 sequences (100000064 bp) in 2.487 CPU sec, 2.687 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 283046, 27, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 413, 1501)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4093)
[M::mem_pestat] mean and std.dev: (625.63, 680.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5389)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 257, 382)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 810)
[M::mem_pestat] mean and std.dev: (286.94, 148.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1024)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (249, 357, 1757)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4773)
[M::mem_pestat] mean and std.dev: (1037.70, 1195.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6281)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 825, 1675)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4567)
[M::mem_pestat] mean and std.dev: (918.69, 893.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6013)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694224 reads in 160.377 CPU sec, 5.104 real sec
[M::process] read 695262 sequences (100000002 bp) in 1.930 CPU sec, 1.949 real sec...
[M::mem_process_seqs] Processed 694504 reads in 108.945 CPU sec, 3.581 real sec
sorting block 37, #reads = 1076264 mem = 536880100 peak = 978354176
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 283984, 25, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 340, 983)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2557)
[M::mem_pestat] mean and std.dev: (496.54, 442.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3344)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 249, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 777)
[M::mem_pestat] mean and std.dev: (278.59, 143.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 981)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (118, 494, 986)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2722)
[M::mem_pestat] mean and std.dev: (489.54, 419.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3590)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 482, 1113)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2863)
[M::mem_pestat] mean and std.dev: (606.89, 443.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3738)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694776 sequences (100000227 bp) in 2.365 CPU sec, 2.522 real sec...
[M::process] read 695044 sequences (100000232 bp) in 1.430 CPU sec, 1.426 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 283328, 31, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 224, 709)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1737)
[M::mem_pestat] mean and std.dev: (365.10, 315.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2251)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 253, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 782)
[M::mem_pestat] mean and std.dev: (280.91, 143.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 987)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 580, 1373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3791)
[M::mem_pestat] mean and std.dev: (597.85, 530.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5000)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 459, 1070)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2724)
[M::mem_pestat] mean and std.dev: (750.54, 707.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3579)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696038 reads in 168.549 CPU sec, 5.517 real sec
[M::mem_process_seqs] Processed 695262 reads in 110.117 CPU sec, 3.495 real sec
sorting block 38, #reads = 1076273 mem = 536879273 peak = 978354176
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 283171, 16, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (287, 404, 898)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2120)
[M::mem_pestat] mean and std.dev: (571.79, 501.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2731)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 254, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 785)
[M::mem_pestat] mean and std.dev: (281.63, 143.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 991)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (53, 374, 610)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1724)
[M::mem_pestat] mean and std.dev: (345.69, 288.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2281)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 357, 576)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1322)
[M::mem_pestat] mean and std.dev: (396.68, 233.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1695)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694806 sequences (100000207 bp) in 2.470 CPU sec, 2.613 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 283103, 18, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 355, 1785)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4881)
[M::mem_pestat] mean and std.dev: (735.72, 924.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6429)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 251, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 776)
[M::mem_pestat] mean and std.dev: (279.94, 143.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 979)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (395, 521, 2130)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5600)
[M::mem_pestat] mean and std.dev: (1105.31, 1463.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7335)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (299, 499, 969)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2309)
[M::mem_pestat] mean and std.dev: (563.18, 464.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2979)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695086 sequences (100000204 bp) in 1.875 CPU sec, 1.876 real sec...
[M::mem_process_seqs] Processed 694776 reads in 168.974 CPU sec, 5.397 real sec
sorting block 39, #reads = 1076856 mem = 536877012 peak = 978354176
[M::mem_process_seqs] Processed 695044 reads in 109.826 CPU sec, 3.473 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 282434, 20, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 219, 384)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 780)
[M::mem_pestat] mean and std.dev: (256.35, 100.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 978)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 251, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 775)
[M::mem_pestat] mean and std.dev: (279.01, 142.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 978)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (768, 974, 1545)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3099)
[M::mem_pestat] mean and std.dev: (1058.58, 568.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3876)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (288, 476, 2170)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5934)
[M::mem_pestat] mean and std.dev: (1156.48, 1214.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7816)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 40, #reads = 1074813 mem = 536879400 peak = 1011167232
[M::process] read 695502 sequences (100000236 bp) in 2.735 CPU sec, 2.918 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 283059, 29, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 454, 586)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1276)
[M::mem_pestat] mean and std.dev: (392.59, 211.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1621)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 250, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 769)
[M::mem_pestat] mean and std.dev: (277.75, 141.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 970)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (855, 1071, 2594)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6072)
[M::mem_pestat] mean and std.dev: (1197.68, 914.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7811)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 491, 926)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2352)
[M::mem_pestat] mean and std.dev: (582.67, 502.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3065)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696294 sequences (100000071 bp) in 1.890 CPU sec, 1.896 real sec...
[M::mem_process_seqs] Processed 694806 reads in 166.444 CPU sec, 5.284 real sec
[M::mem_process_seqs] Processed 695086 reads in 115.140 CPU sec, 3.653 real sec
sorting block 41, #reads = 1074468 mem = 536881056 peak = 1011167232
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 283649, 20, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 290, 578)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1376)
[M::mem_pestat] mean and std.dev: (375.61, 295.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1775)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 249, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (276.79, 140.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 962)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 724, 1390)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3714)
[M::mem_pestat] mean and std.dev: (1014.80, 991.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4980)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 256, 530)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1158)
[M::mem_pestat] mean and std.dev: (300.95, 176.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1472)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695620 sequences (100000049 bp) in 2.542 CPU sec, 2.703 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 283751, 15, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 376, 615)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1523)
[M::mem_pestat] mean and std.dev: (364.52, 261.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1977)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 247, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (273.74, 138.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 952)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (576, 1390, 2158)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5322)
[M::mem_pestat] mean and std.dev: (1395.43, 1223.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6904)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (304, 1438, 2088)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5656)
[M::mem_pestat] mean and std.dev: (1497.16, 1345.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7440)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695362 sequences (100000102 bp) in 1.840 CPU sec, 1.847 real sec...
[M::mem_process_seqs] Processed 695502 reads in 163.169 CPU sec, 5.188 real sec
[M::mem_process_seqs] Processed 696294 reads in 110.649 CPU sec, 3.600 real sec
sorting block 42, #reads = 1075768 mem = 536879638 peak = 1011167232
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 282684, 17, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 336, 759)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1929)
[M::mem_pestat] mean and std.dev: (455.81, 355.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2514)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 249, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (276.30, 140.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 962)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (324, 621, 1610)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4182)
[M::mem_pestat] mean and std.dev: (1036.24, 1016.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5468)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 371, 539)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1139)
[M::mem_pestat] mean and std.dev: (409.82, 219.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1439)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695130 sequences (100000256 bp) in 2.558 CPU sec, 2.706 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 283434, 31, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 353, 4282)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12394)
[M::mem_pestat] mean and std.dev: (1603.75, 2190.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16450)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 250, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 769)
[M::mem_pestat] mean and std.dev: (277.81, 141.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 970)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (548, 862, 2255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5669)
[M::mem_pestat] mean and std.dev: (1385.39, 1203.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7376)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 353, 1178)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3188)
[M::mem_pestat] mean and std.dev: (727.88, 758.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4193)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695074 sequences (100000088 bp) in 1.860 CPU sec, 1.860 real sec...
[M::mem_process_seqs] Processed 695620 reads in 168.508 CPU sec, 5.431 real sec
[M::mem_process_seqs] Processed 695362 reads in 110.615 CPU sec, 3.493 real sec
sorting block 43, #reads = 1075030 mem = 536880987 peak = 1011167232
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 283385, 17, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 403, 928)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2328)
[M::mem_pestat] mean and std.dev: (486.27, 435.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3028)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 250, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 769)
[M::mem_pestat] mean and std.dev: (277.74, 141.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 970)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (116, 304, 2522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7334)
[M::mem_pestat] mean and std.dev: (1122.12, 1525.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9740)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 372, 652)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1504)
[M::mem_pestat] mean and std.dev: (387.54, 279.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1930)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694958 sequences (100000206 bp) in 2.578 CPU sec, 2.738 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 282560, 16, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 502, 1064)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2692)
[M::mem_pestat] mean and std.dev: (646.68, 524.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3506)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 250, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 766)
[M::mem_pestat] mean and std.dev: (277.48, 141.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 966)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (590, 1211, 2470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6230)
[M::mem_pestat] mean and std.dev: (1702.25, 1384.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8110)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 764, 2298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6494)
[M::mem_pestat] mean and std.dev: (921.63, 1262.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8592)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694594 sequences (100000030 bp) in 1.870 CPU sec, 1.866 real sec...
[M::mem_process_seqs] Processed 695130 reads in 169.426 CPU sec, 5.402 real sec
sorting block 44, #reads = 1074437 mem = 536878709 peak = 1026043904
[M::mem_process_seqs] Processed 695074 reads in 109.617 CPU sec, 3.557 real sec
sorting block 45, #reads = 1075201 mem = 536881695 peak = 1026043904
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 283237, 18, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 518, 1305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3565)
[M::mem_pestat] mean and std.dev: (709.79, 642.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4695)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 252, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (279.09, 141.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 975)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (395, 1571, 2680)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7250)
[M::mem_pestat] mean and std.dev: (1961.39, 2009.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10000)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 278, 557)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1189)
[M::mem_pestat] mean and std.dev: (394.03, 245.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1505)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694904 sequences (100000057 bp) in 2.483 CPU sec, 2.635 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 282415, 32, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (416, 606, 1204)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2780)
[M::mem_pestat] mean and std.dev: (783.13, 588.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3568)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 252, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (279.12, 141.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 975)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (309, 590, 1130)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2772)
[M::mem_pestat] mean and std.dev: (699.48, 701.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3593)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (301, 503, 1740)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4618)
[M::mem_pestat] mean and std.dev: (980.81, 908.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6057)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694552 sequences (100000197 bp) in 1.850 CPU sec, 1.848 real sec...
[M::mem_process_seqs] Processed 694958 reads in 162.199 CPU sec, 5.237 real sec
[M::mem_process_seqs] Processed 694594 reads in 108.929 CPU sec, 3.622 real sec
sorting block 46, #reads = 1075383 mem = 536881154 peak = 1026043904
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 283260, 33, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 631, 1144)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2988)
[M::mem_pestat] mean and std.dev: (811.71, 761.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3910)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 251, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 772)
[M::mem_pestat] mean and std.dev: (278.58, 141.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 974)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (384, 726, 1354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3294)
[M::mem_pestat] mean and std.dev: (859.56, 737.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4264)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (340, 451, 1793)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4699)
[M::mem_pestat] mean and std.dev: (1056.71, 1299.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6255)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695440 sequences (100000000 bp) in 2.597 CPU sec, 2.722 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 283096, 18, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 312, 573)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1283)
[M::mem_pestat] mean and std.dev: (324.51, 207.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1638)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 253, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 776)
[M::mem_pestat] mean and std.dev: (280.29, 142.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 979)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (757, 1319, 1863)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4075)
[M::mem_pestat] mean and std.dev: (1267.06, 974.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5181)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 387, 1427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3967)
[M::mem_pestat] mean and std.dev: (645.47, 632.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5237)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696750 sequences (100000173 bp) in 1.840 CPU sec, 1.836 real sec...
[M::mem_process_seqs] Processed 694904 reads in 166.411 CPU sec, 5.459 real sec
[M::mem_process_seqs] Processed 694552 reads in 108.709 CPU sec, 3.442 real sec
sorting block 47, #reads = 1074747 mem = 536878722 peak = 1026043904
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 282882, 12, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 323, 972)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2504)
[M::mem_pestat] mean and std.dev: (538.73, 529.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3270)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 250, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 766)
[M::mem_pestat] mean and std.dev: (277.11, 140.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 966)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (469, 957, 1810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4492)
[M::mem_pestat] mean and std.dev: (1125.67, 1057.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5833)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 244, 602)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1428)
[M::mem_pestat] mean and std.dev: (393.51, 296.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1841)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696324 sequences (100000225 bp) in 2.516 CPU sec, 2.664 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 283110, 19, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (319, 891, 5031)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 14455)
[M::mem_pestat] mean and std.dev: (2182.20, 2372.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 19167)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 247, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 769)
[M::mem_pestat] mean and std.dev: (275.08, 140.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 971)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (269, 443, 1365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3557)
[M::mem_pestat] mean and std.dev: (713.83, 813.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4653)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 331, 752)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1836)
[M::mem_pestat] mean and std.dev: (453.50, 340.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2378)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695400 sequences (100000081 bp) in 1.560 CPU sec, 1.566 real sec...
[M::mem_process_seqs] Processed 695440 reads in 164.635 CPU sec, 5.224 real sec
sorting block 48, #reads = 1074722 mem = 536881479 peak = 1026043904
[M::mem_process_seqs] Processed 696750 reads in 108.544 CPU sec, 3.439 real sec
sorting block 49, #reads = 1075053 mem = 536879117 peak = 1028964352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 283848, 18, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 350, 613)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1417)
[M::mem_pestat] mean and std.dev: (391.23, 302.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1819)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 250, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 783)
[M::mem_pestat] mean and std.dev: (279.20, 144.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 989)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (77, 702, 1223)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3515)
[M::mem_pestat] mean and std.dev: (704.12, 660.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4661)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 419, 798)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2002)
[M::mem_pestat] mean and std.dev: (442.88, 367.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2604)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694902 sequences (100000210 bp) in 2.575 CPU sec, 2.693 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 283147, 18, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 270, 670)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1744)
[M::mem_pestat] mean and std.dev: (332.37, 304.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2281)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 252, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 790)
[M::mem_pestat] mean and std.dev: (281.74, 145.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 998)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (71, 846, 2820)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8318)
[M::mem_pestat] mean and std.dev: (1643.24, 2361.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11088)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 374, 1150)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2992)
[M::mem_pestat] mean and std.dev: (508.50, 448.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3913)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694534 sequences (100000245 bp) in 1.799 CPU sec, 1.800 real sec...
[M::mem_process_seqs] Processed 696324 reads in 164.447 CPU sec, 5.302 real sec
[M::mem_process_seqs] Processed 695400 reads in 109.107 CPU sec, 3.459 real sec
sorting block 50, #reads = 1078183 mem = 536880016 peak = 1028964352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 282941, 23, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (403, 555, 941)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2017)
[M::mem_pestat] mean and std.dev: (679.55, 404.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2555)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 255, 377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 797)
[M::mem_pestat] mean and std.dev: (283.40, 145.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1007)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 285, 1568)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4308)
[M::mem_pestat] mean and std.dev: (783.74, 783.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5678)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (287, 430, 833)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1925)
[M::mem_pestat] mean and std.dev: (464.50, 291.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2471)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694024 sequences (100000272 bp) in 2.789 CPU sec, 2.906 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 283048, 30, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 253, 657)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1601)
[M::mem_pestat] mean and std.dev: (340.73, 224.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2073)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 256, 379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 801)
[M::mem_pestat] mean and std.dev: (285.41, 147.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1012)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (698, 1647, 3011)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7637)
[M::mem_pestat] mean and std.dev: (1670.80, 1107.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9950)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 344, 714)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1730)
[M::mem_pestat] mean and std.dev: (438.55, 382.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2238)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694902 reads in 160.664 CPU sec, 5.105 real sec
[M::process] read 693400 sequences (100000169 bp) in 2.230 CPU sec, 2.267 real sec...
sorting block 51, #reads = 1077960 mem = 536877350 peak = 1028964352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 282806, 22, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 475, 1216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3190)
[M::mem_pestat] mean and std.dev: (610.50, 494.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4177)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 259, 384)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 814)
[M::mem_pestat] mean and std.dev: (287.97, 148.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1029)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (104, 397, 2187)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6353)
[M::mem_pestat] mean and std.dev: (1000.95, 1086.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8436)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 362, 530)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1192)
[M::mem_pestat] mean and std.dev: (356.64, 204.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1523)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693122 sequences (100000002 bp) in 2.018 CPU sec, 2.027 real sec...
[M::mem_process_seqs] Processed 694024 reads in 94.529 CPU sec, 2.988 real sec
[M::mem_process_seqs] Processed 694534 reads in 238.847 CPU sec, 7.561 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 282371, 22, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 436, 645)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1541)
[M::mem_pestat] mean and std.dev: (537.94, 370.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2021)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 261, 385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 813)
[M::mem_pestat] mean and std.dev: (289.38, 148.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1027)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (448, 988, 1032)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2200)
[M::mem_pestat] mean and std.dev: (721.00, 428.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2784)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 366, 484)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1036)
[M::mem_pestat] mean and std.dev: (326.62, 158.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1312)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 52, #reads = 1076641 mem = 536878665 peak = 1028964352
[M::process] read 695286 sequences (100000002 bp) in 2.654 CPU sec, 2.792 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 282256, 55, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 443, 792)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1990)
[M::mem_pestat] mean and std.dev: (424.40, 322.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2589)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 263, 389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 823)
[M::mem_pestat] mean and std.dev: (291.86, 150.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1040)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (348, 746, 1925)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5079)
[M::mem_pestat] mean and std.dev: (1137.77, 1012.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6656)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 392, 1674)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4524)
[M::mem_pestat] mean and std.dev: (730.51, 905.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5949)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 693400 reads in 178.490 CPU sec, 5.662 real sec
[M::mem_process_seqs] Processed 693122 reads in 109.211 CPU sec, 3.447 real sec
[M::process] read 695258 sequences (100000181 bp) in 2.387 CPU sec, 2.516 real sec...
sorting block 53, #reads = 1077076 mem = 536886066 peak = 1028964352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 283190, 41, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 302, 812)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2024)
[M::mem_pestat] mean and std.dev: (412.52, 329.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2630)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 253, 375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 793)
[M::mem_pestat] mean and std.dev: (282.74, 146.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1002)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 1522, 3516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10164)
[M::mem_pestat] mean and std.dev: (1703.20, 1451.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13488)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 429, 1951)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5427)
[M::mem_pestat] mean and std.dev: (833.06, 775.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7165)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694478 sequences (100000098 bp) in 2.546 CPU sec, 2.672 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 283515, 25, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 479, 886)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2262)
[M::mem_pestat] mean and std.dev: (651.11, 646.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3238)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 252, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 784)
[M::mem_pestat] mean and std.dev: (281.01, 144.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 990)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 540, 1160)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3088)
[M::mem_pestat] mean and std.dev: (637.96, 494.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4052)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (260, 412, 532)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1076)
[M::mem_pestat] mean and std.dev: (348.84, 139.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1348)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695286 reads in 161.594 CPU sec, 5.130 real sec
[M::mem_process_seqs] Processed 695258 reads in 108.017 CPU sec, 3.406 real sec
[M::process] read 694946 sequences (100000220 bp) in 2.120 CPU sec, 2.160 real sec...
sorting block 54, #reads = 1076584 mem = 536880837 peak = 1028964352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 283283, 28, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (258, 512, 1530)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4074)
[M::mem_pestat] mean and std.dev: (1045.34, 1168.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5720)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 254, 376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 792)
[M::mem_pestat] mean and std.dev: (283.28, 145.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1000)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 393, 2222)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6400)
[M::mem_pestat] mean and std.dev: (1472.04, 2167.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10143)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 607, 1161)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3051)
[M::mem_pestat] mean and std.dev: (648.94, 533.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3996)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 55, #reads = 1076896 mem = 536879098 peak = 1028964352
[M::process] read 694824 sequences (100000122 bp) in 2.517 CPU sec, 2.681 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 282650, 24, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 238, 612)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1558)
[M::mem_pestat] mean and std.dev: (383.90, 342.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2031)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 251, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (279.47, 142.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 975)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (89, 333, 580)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1562)
[M::mem_pestat] mean and std.dev: (334.77, 304.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2053)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 305, 550)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1160)
[M::mem_pestat] mean and std.dev: (333.46, 160.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1465)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694478 reads in 162.027 CPU sec, 5.154 real sec
[M::process] read 694826 sequences (100000219 bp) in 1.899 CPU sec, 1.904 real sec...
[M::mem_process_seqs] Processed 694946 reads in 108.422 CPU sec, 3.639 real sec
sorting block 56, #reads = 1075994 mem = 536876291 peak = 1028964352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 282826, 15, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 332, 1715)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4703)
[M::mem_pestat] mean and std.dev: (874.00, 858.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6197)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 251, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (279.66, 142.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 975)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (472, 704, 5763)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 16345)
[M::mem_pestat] mean and std.dev: (2906.27, 3564.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 21636)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 317, 642)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1512)
[M::mem_pestat] mean and std.dev: (440.53, 303.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1947)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694800 sequences (100000260 bp) in 2.609 CPU sec, 2.755 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 282791, 15, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 380, 1272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3384)
[M::mem_pestat] mean and std.dev: (835.23, 871.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4440)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 250, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 769)
[M::mem_pestat] mean and std.dev: (278.17, 141.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 970)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (612, 732, 1414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3018)
[M::mem_pestat] mean and std.dev: (1029.20, 695.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3820)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (427, 790, 1157)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2617)
[M::mem_pestat] mean and std.dev: (830.47, 563.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3347)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694866 sequences (100000223 bp) in 1.850 CPU sec, 1.854 real sec...
[M::mem_process_seqs] Processed 694824 reads in 167.520 CPU sec, 5.538 real sec
[M::mem_process_seqs] Processed 694826 reads in 109.946 CPU sec, 3.477 real sec
sorting block 57, #reads = 1075362 mem = 536883605 peak = 1028964352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 282750, 27, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (291, 411, 871)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2031)
[M::mem_pestat] mean and std.dev: (491.33, 308.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2611)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 251, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 767)
[M::mem_pestat] mean and std.dev: (278.16, 140.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 967)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (269, 1091, 1886)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5120)
[M::mem_pestat] mean and std.dev: (1094.54, 1060.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6737)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 386, 800)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1920)
[M::mem_pestat] mean and std.dev: (510.20, 359.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2480)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694456 sequences (100000048 bp) in 2.109 CPU sec, 2.239 real sec...
[M::process] read 695074 sequences (100000222 bp) in 1.430 CPU sec, 1.438 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 282981, 25, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 407, 767)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1931)
[M::mem_pestat] mean and std.dev: (449.50, 321.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2513)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 251, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 770)
[M::mem_pestat] mean and std.dev: (278.78, 141.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 971)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 1016, 3353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9685)
[M::mem_pestat] mean and std.dev: (1569.67, 1672.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12851)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 736, 1275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3387)
[M::mem_pestat] mean and std.dev: (707.77, 664.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4443)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694800 reads in 159.421 CPU sec, 5.081 real sec
sorting block 58, #reads = 1075662 mem = 536880716 peak = 1028964352
[M::mem_process_seqs] Processed 694866 reads in 107.122 CPU sec, 3.402 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 283216, 22, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (289, 915, 1810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4852)
[M::mem_pestat] mean and std.dev: (1152.37, 1169.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6373)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 252, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 776)
[M::mem_pestat] mean and std.dev: (279.54, 141.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 979)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 556, 1248)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3442)
[M::mem_pestat] mean and std.dev: (645.19, 594.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4539)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 482, 1158)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3030)
[M::mem_pestat] mean and std.dev: (597.10, 535.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3966)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695464 sequences (100000135 bp) in 2.533 CPU sec, 2.707 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 282763, 30, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 315, 631)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1515)
[M::mem_pestat] mean and std.dev: (361.70, 294.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1957)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 250, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 769)
[M::mem_pestat] mean and std.dev: (277.87, 141.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 970)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 441, 1048)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2750)
[M::mem_pestat] mean and std.dev: (569.90, 503.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3601)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (325, 606, 1408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3574)
[M::mem_pestat] mean and std.dev: (793.27, 688.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4657)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695316 sequences (100000058 bp) in 1.810 CPU sec, 1.814 real sec...
[M::mem_process_seqs] Processed 694456 reads in 163.211 CPU sec, 5.187 real sec
sorting block 59, #reads = 1075595 mem = 536879707 peak = 1028964352
[M::mem_process_seqs] Processed 695074 reads in 121.238 CPU sec, 3.874 real sec
sorting block 60, #reads = 1075319 mem = 536877047 peak = 1083936768
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 283580, 27, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (260, 468, 2460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6860)
[M::mem_pestat] mean and std.dev: (1243.36, 1421.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9060)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 771)
[M::mem_pestat] mean and std.dev: (277.50, 142.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 973)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 535, 867)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2153)
[M::mem_pestat] mean and std.dev: (522.39, 407.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2796)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 466, 573)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1293)
[M::mem_pestat] mean and std.dev: (387.05, 261.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1653)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694698 sequences (100000266 bp) in 2.601 CPU sec, 2.733 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 283182, 23, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (288, 463, 2336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6432)
[M::mem_pestat] mean and std.dev: (1062.33, 1283.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8480)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 249, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (276.62, 140.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 962)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (336, 498, 1639)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4245)
[M::mem_pestat] mean and std.dev: (813.59, 716.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5548)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 317, 1255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3367)
[M::mem_pestat] mean and std.dev: (925.21, 959.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4763)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694408 sequences (100000019 bp) in 1.800 CPU sec, 1.805 real sec...
[M::mem_process_seqs] Processed 695464 reads in 169.689 CPU sec, 5.397 real sec
[M::mem_process_seqs] Processed 695316 reads in 114.908 CPU sec, 3.650 real sec
sorting block 61, #reads = 1075322 mem = 536877415 peak = 1083936768
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 283010, 14, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (316, 528, 1193)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2947)
[M::mem_pestat] mean and std.dev: (757.13, 729.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3824)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 252, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (279.25, 141.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 975)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (11, 1417, 1682)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5024)
[M::mem_pestat] mean and std.dev: (728.25, 729.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6695)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (326, 444, 1038)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2462)
[M::mem_pestat] mean and std.dev: (713.00, 584.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3174)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694194 sequences (100000270 bp) in 2.745 CPU sec, 2.934 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 283158, 27, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 466, 1807)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4975)
[M::mem_pestat] mean and std.dev: (932.93, 807.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6559)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 253, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 774)
[M::mem_pestat] mean and std.dev: (280.08, 141.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 976)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (88, 631, 1091)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3097)
[M::mem_pestat] mean and std.dev: (717.85, 767.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4100)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 340, 1735)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4727)
[M::mem_pestat] mean and std.dev: (854.62, 975.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6223)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694404 sequences (100000076 bp) in 1.861 CPU sec, 1.865 real sec...
[M::mem_process_seqs] Processed 694698 reads in 182.906 CPU sec, 5.962 real sec
[M::mem_process_seqs] Processed 694408 reads in 120.909 CPU sec, 3.921 real sec
sorting block 62, #reads = 1075116 mem = 536879637 peak = 1083936768
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 282750, 16, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (334, 474, 893)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2011)
[M::mem_pestat] mean and std.dev: (544.62, 378.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2570)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 255, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 778)
[M::mem_pestat] mean and std.dev: (281.65, 142.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 981)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (277, 579, 974)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2368)
[M::mem_pestat] mean and std.dev: (549.53, 340.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3065)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 514, 1541)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4221)
[M::mem_pestat] mean and std.dev: (753.53, 626.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5561)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694892 sequences (100000200 bp) in 2.700 CPU sec, 3.132 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 282907, 31, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (267, 446, 579)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1203)
[M::mem_pestat] mean and std.dev: (449.68, 258.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1515)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 254, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 780)
[M::mem_pestat] mean and std.dev: (280.97, 142.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 984)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (432, 717, 1117)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2487)
[M::mem_pestat] mean and std.dev: (649.86, 511.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3172)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 368, 987)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2629)
[M::mem_pestat] mean and std.dev: (539.74, 467.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3450)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694194 reads in 177.708 CPU sec, 5.689 real sec
[M::process] read 702768 sequences (100000026 bp) in 1.947 CPU sec, 1.956 real sec...
sorting block 63, #reads = 1073754 mem = 536880928 peak = 1083936768
[M::mem_process_seqs] Processed 694404 reads in 123.280 CPU sec, 3.922 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 282803, 9, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 437, 633)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1497)
[M::mem_pestat] mean and std.dev: (386.96, 266.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1929)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 252, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 776)
[M::mem_pestat] mean and std.dev: (279.70, 141.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 979)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 407, 1198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3170)
[M::mem_pestat] mean and std.dev: (817.07, 776.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4156)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 64, #reads = 1075626 mem = 536881500 peak = 1083936768
[M::process] read 700986 sequences (100000289 bp) in 2.724 CPU sec, 2.871 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 286283, 18, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (279, 386, 652)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1398)
[M::mem_pestat] mean and std.dev: (426.85, 245.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1771)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 226, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 708)
[M::mem_pestat] mean and std.dev: (257.27, 134.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 893)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 736, 839)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2215)
[M::mem_pestat] mean and std.dev: (589.56, 513.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2903)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 738, 2411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6791)
[M::mem_pestat] mean and std.dev: (1306.68, 1626.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8981)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701030 sequences (100000082 bp) in 1.905 CPU sec, 1.910 real sec...
[M::mem_process_seqs] Processed 694892 reads in 195.611 CPU sec, 6.344 real sec
[M::mem_process_seqs] Processed 702768 reads in 132.212 CPU sec, 4.203 real sec
sorting block 65, #reads = 1074539 mem = 536882661 peak = 1083936768
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 285573, 19, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (281, 893, 1918)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5192)
[M::mem_pestat] mean and std.dev: (1086.22, 947.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6829)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 231, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 729)
[M::mem_pestat] mean and std.dev: (263.05, 137.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 920)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 569, 1374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3706)
[M::mem_pestat] mean and std.dev: (748.06, 799.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4872)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 288, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 992)
[M::mem_pestat] mean and std.dev: (278.15, 137.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1259)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700140 sequences (100000165 bp) in 2.713 CPU sec, 3.112 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 285530, 18, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 424, 807)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2005)
[M::mem_pestat] mean and std.dev: (522.61, 456.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2604)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 232, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 735)
[M::mem_pestat] mean and std.dev: (264.02, 138.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 928)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (116, 869, 1532)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4364)
[M::mem_pestat] mean and std.dev: (1101.50, 1264.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6161)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 222, 684)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1700)
[M::mem_pestat] mean and std.dev: (447.34, 421.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2208)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698860 sequences (100000224 bp) in 1.975 CPU sec, 1.981 real sec...
[M::mem_process_seqs] Processed 700986 reads in 190.038 CPU sec, 6.087 real sec
[M::mem_process_seqs] Processed 701030 reads in 129.220 CPU sec, 4.104 real sec
sorting block 66, #reads = 1077720 mem = 536877253 peak = 1083936768
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 285280, 27, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 309, 1043)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2717)
[M::mem_pestat] mean and std.dev: (624.39, 661.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3554)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 234, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 742)
[M::mem_pestat] mean and std.dev: (266.33, 138.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 937)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (31, 323, 1290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3808)
[M::mem_pestat] mean and std.dev: (509.84, 568.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5067)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 448, 1500)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4094)
[M::mem_pestat] mean and std.dev: (1039.65, 1236.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5984)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697546 sequences (100000231 bp) in 2.696 CPU sec, 3.030 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 285144, 14, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 477, 1221)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3213)
[M::mem_pestat] mean and std.dev: (655.12, 592.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4209)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 240, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (271.10, 140.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 964)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (253, 1079, 1310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3424)
[M::mem_pestat] mean and std.dev: (1007.86, 816.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4481)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (306, 683, 1652)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4344)
[M::mem_pestat] mean and std.dev: (915.74, 862.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5690)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697892 sequences (100000145 bp) in 1.867 CPU sec, 1.877 real sec...
[M::mem_process_seqs] Processed 700140 reads in 197.676 CPU sec, 6.622 real sec
sorting block 67, #reads = 1076675 mem = 536879738 peak = 1083936768
[M::mem_process_seqs] Processed 698860 reads in 128.558 CPU sec, 4.123 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 284384, 12, 16)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 283, 761)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1981)
[M::mem_pestat] mean and std.dev: (365.82, 346.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2591)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 243, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 770)
[M::mem_pestat] mean and std.dev: (274.43, 142.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 973)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (357, 727, 1118)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2640)
[M::mem_pestat] mean and std.dev: (702.64, 397.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3401)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 314, 671)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1677)
[M::mem_pestat] mean and std.dev: (388.38, 294.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2180)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 68, #reads = 1076749 mem = 536878969 peak = 1083936768
[M::process] read 699964 sequences (100000075 bp) in 2.535 CPU sec, 2.891 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 284499, 15, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 278, 724)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1798)
[M::mem_pestat] mean and std.dev: (409.62, 381.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2335)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 243, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 770)
[M::mem_pestat] mean and std.dev: (273.95, 142.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 973)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (414, 751, 1886)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4830)
[M::mem_pestat] mean and std.dev: (926.31, 863.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6302)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 424, 968)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2398)
[M::mem_pestat] mean and std.dev: (585.00, 472.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3113)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700992 sequences (100000242 bp) in 2.050 CPU sec, 2.063 real sec...
[M::mem_process_seqs] Processed 697546 reads in 187.255 CPU sec, 6.035 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 285486, 15, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 451, 1005)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2661)
[M::mem_pestat] mean and std.dev: (563.31, 523.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3489)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 743)
[M::mem_pestat] mean and std.dev: (266.51, 138.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 938)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (325, 362, 1505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3865)
[M::mem_pestat] mean and std.dev: (1059.00, 1084.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5396)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (273, 358, 483)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 903)
[M::mem_pestat] mean and std.dev: (327.17, 145.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1113)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701154 sequences (100000277 bp) in 2.340 CPU sec, 2.364 real sec...
[M::mem_process_seqs] Processed 699964 reads in 109.852 CPU sec, 3.572 real sec
sorting block 69, #reads = 1075981 mem = 536880655 peak = 1083936768
[M::mem_process_seqs] Processed 697892 reads in 274.750 CPU sec, 8.855 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 285777, 16, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 329, 608)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1472)
[M::mem_pestat] mean and std.dev: (359.35, 221.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1904)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 231, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 723)
[M::mem_pestat] mean and std.dev: (261.78, 135.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 912)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 745, 1608)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4496)
[M::mem_pestat] mean and std.dev: (670.00, 652.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5940)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 283, 561)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1179)
[M::mem_pestat] mean and std.dev: (333.39, 185.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1488)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701410 sequences (100000123 bp) in 3.116 CPU sec, 3.588 real sec...
sorting block 70, #reads = 1075527 mem = 536880612 peak = 1083936768
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 285535, 31, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 418, 1323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3601)
[M::mem_pestat] mean and std.dev: (589.56, 551.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4740)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 231, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 723)
[M::mem_pestat] mean and std.dev: (261.42, 134.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 912)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 494, 868)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2168)
[M::mem_pestat] mean and std.dev: (511.10, 474.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2818)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 298, 816)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2102)
[M::mem_pestat] mean and std.dev: (455.47, 428.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2745)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700992 reads in 220.178 CPU sec, 7.070 real sec
[M::mem_process_seqs] Processed 701154 reads in 138.419 CPU sec, 4.426 real sec
[M::process] read 700304 sequences (100000272 bp) in 2.675 CPU sec, 2.817 real sec...
sorting block 71, #reads = 1075225 mem = 536878112 peak = 1083936768
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 285642, 16, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 325, 616)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1442)
[M::mem_pestat] mean and std.dev: (334.62, 202.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1855)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 230, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 722)
[M::mem_pestat] mean and std.dev: (260.89, 134.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 911)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (61, 892, 1859)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5455)
[M::mem_pestat] mean and std.dev: (736.43, 781.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7253)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 289, 1057)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2739)
[M::mem_pestat] mean and std.dev: (560.06, 565.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3580)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698926 sequences (100000043 bp) in 2.796 CPU sec, 2.995 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 285337, 23, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (536, 575, 1557)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3599)
[M::mem_pestat] mean and std.dev: (932.37, 756.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4620)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 234, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 736)
[M::mem_pestat] mean and std.dev: (264.87, 136.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 929)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (780, 1231, 2400)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5640)
[M::mem_pestat] mean and std.dev: (1195.84, 813.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7260)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 326, 1667)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4609)
[M::mem_pestat] mean and std.dev: (746.35, 782.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6080)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699132 sequences (100000219 bp) in 1.996 CPU sec, 2.002 real sec...
[M::mem_process_seqs] Processed 701410 reads in 208.121 CPU sec, 6.633 real sec
[M::mem_process_seqs] Processed 700304 reads in 138.072 CPU sec, 4.384 real sec
sorting block 72, #reads = 1071779 mem = 536881034 peak = 1083936768
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 284801, 26, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (314, 367, 640)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1292)
[M::mem_pestat] mean and std.dev: (360.97, 202.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1618)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 238, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 747)
[M::mem_pestat] mean and std.dev: (268.58, 138.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 943)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (350, 1606, 2691)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7373)
[M::mem_pestat] mean and std.dev: (1674.84, 1549.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9714)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (315, 561, 1372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3486)
[M::mem_pestat] mean and std.dev: (666.96, 463.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4543)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702538 sequences (100000266 bp) in 3.005 CPU sec, 3.421 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 284138, 28, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 408, 718)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1796)
[M::mem_pestat] mean and std.dev: (458.95, 391.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2335)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 236, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 738)
[M::mem_pestat] mean and std.dev: (266.81, 137.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 931)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (368, 455, 1934)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5066)
[M::mem_pestat] mean and std.dev: (901.07, 872.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6632)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 383, 1044)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2744)
[M::mem_pestat] mean and std.dev: (679.91, 658.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3594)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700080 sequences (100000049 bp) in 2.078 CPU sec, 2.085 real sec...
[M::mem_process_seqs] Processed 698926 reads in 206.318 CPU sec, 6.669 real sec
sorting block 73, #reads = 1072850 mem = 536884371 peak = 1083936768
[M::mem_process_seqs] Processed 699132 reads in 139.219 CPU sec, 4.467 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (17, 285592, 25, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 300, 509)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1203)
[M::mem_pestat] mean and std.dev: (321.25, 176.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1550)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 227, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 708)
[M::mem_pestat] mean and std.dev: (256.73, 131.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 893)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 403, 1328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3528)
[M::mem_pestat] mean and std.dev: (600.61, 527.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4628)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (277, 340, 549)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1093)
[M::mem_pestat] mean and std.dev: (364.54, 181.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1365)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 74, #reads = 1074556 mem = 536880076 peak = 1083936768
[M::process] read 698018 sequences (100000270 bp) in 2.955 CPU sec, 3.078 real sec...
[M::process] read 698558 sequences (100000043 bp) in 2.196 CPU sec, 2.199 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 284707, 22, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 358, 1646)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4408)
[M::mem_pestat] mean and std.dev: (811.14, 844.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5789)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 235, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 727)
[M::mem_pestat] mean and std.dev: (263.56, 134.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 917)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 421, 2540)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7334)
[M::mem_pestat] mean and std.dev: (1087.68, 1459.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9731)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 482, 887)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2219)
[M::mem_pestat] mean and std.dev: (632.51, 572.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2922)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702538 reads in 233.790 CPU sec, 7.503 real sec
[M::mem_process_seqs] Processed 700080 reads in 153.958 CPU sec, 4.897 real sec
sorting block 75, #reads = 1066208 mem = 536877950 peak = 1083936768
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 283537, 23, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 357, 780)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1938)
[M::mem_pestat] mean and std.dev: (563.77, 473.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2517)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 240, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 740)
[M::mem_pestat] mean and std.dev: (268.82, 137.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 933)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (121, 288, 663)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1747)
[M::mem_pestat] mean and std.dev: (404.86, 397.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2289)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 261, 1243)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3305)
[M::mem_pestat] mean and std.dev: (582.97, 611.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4336)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698080 sequences (100000031 bp) in 2.981 CPU sec, 3.126 real sec...
[M::process] read 698450 sequences (100000260 bp) in 2.015 CPU sec, 2.019 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 283569, 26, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 383, 1045)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2709)
[M::mem_pestat] mean and std.dev: (543.22, 496.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3541)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 239, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 745)
[M::mem_pestat] mean and std.dev: (268.77, 138.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 940)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (263, 476, 1936)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5282)
[M::mem_pestat] mean and std.dev: (1128.92, 1369.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6955)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (273, 384, 557)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1125)
[M::mem_pestat] mean and std.dev: (406.93, 209.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1409)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698018 reads in 207.318 CPU sec, 6.594 real sec
[M::mem_process_seqs] Processed 698558 reads in 138.190 CPU sec, 4.392 real sec
sorting block 76, #reads = 1067948 mem = 536885254 peak = 1083936768
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 284314, 23, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 411, 992)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2604)
[M::mem_pestat] mean and std.dev: (597.57, 634.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3410)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 239, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (269.77, 138.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 944)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (302, 600, 829)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1883)
[M::mem_pestat] mean and std.dev: (519.85, 374.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2410)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 338, 883)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2229)
[M::mem_pestat] mean and std.dev: (558.72, 523.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2902)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698236 sequences (100000264 bp) in 2.683 CPU sec, 2.814 real sec...
[M::process] read 704390 sequences (100000234 bp) in 2.058 CPU sec, 2.061 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 283732, 16, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 517, 1009)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2585)
[M::mem_pestat] mean and std.dev: (605.10, 508.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3373)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 238, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 736)
[M::mem_pestat] mean and std.dev: (267.26, 136.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 928)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (379, 666, 1177)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2773)
[M::mem_pestat] mean and std.dev: (537.69, 278.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3571)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 351, 733)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1759)
[M::mem_pestat] mean and std.dev: (454.83, 372.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2272)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698080 reads in 215.236 CPU sec, 6.907 real sec
sorting block 77, #reads = 1069537 mem = 536886470 peak = 1083936768
[M::mem_process_seqs] Processed 698450 reads in 145.229 CPU sec, 4.681 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 284345, 28, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 367, 877)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2275)
[M::mem_pestat] mean and std.dev: (418.55, 313.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2974)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 239, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 745)
[M::mem_pestat] mean and std.dev: (268.93, 138.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 940)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (279, 741, 1355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3507)
[M::mem_pestat] mean and std.dev: (730.17, 686.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4583)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (292, 361, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (14, 709)
[M::mem_pestat] mean and std.dev: (312.77, 94.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 848)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704974 sequences (100000111 bp) in 3.004 CPU sec, 3.176 real sec...
[M::process] read 702164 sequences (100000061 bp) in 2.211 CPU sec, 2.212 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 286071, 25, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (258, 310, 931)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2277)
[M::mem_pestat] mean and std.dev: (492.97, 459.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2950)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 221, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (251.67, 129.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 867)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 277, 2572)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7422)
[M::mem_pestat] mean and std.dev: (1393.64, 1853.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9847)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 305, 932)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2468)
[M::mem_pestat] mean and std.dev: (461.45, 382.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3236)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698236 reads in 223.421 CPU sec, 7.151 real sec
sorting block 78, #reads = 1069222 mem = 536880366 peak = 1083936768
[M::mem_process_seqs] Processed 704390 reads in 153.570 CPU sec, 4.885 real sec
sorting block 79, #reads = 1067840 mem = 536880449 peak = 1163698176
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 286542, 17, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 539, 1300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3540)
[M::mem_pestat] mean and std.dev: (550.52, 458.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4660)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 221, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684)
[M::mem_pestat] mean and std.dev: (250.04, 128.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 862)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (430, 1636, 1639)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4057)
[M::mem_pestat] mean and std.dev: (1250.69, 958.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5266)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 441, 1050)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2658)
[M::mem_pestat] mean and std.dev: (671.10, 547.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3462)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701980 sequences (100000250 bp) in 2.766 CPU sec, 2.944 real sec...
[M::process] read 700014 sequences (100000162 bp) in 2.012 CPU sec, 2.017 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 286273, 21, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 257, 1888)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5340)
[M::mem_pestat] mean and std.dev: (874.27, 1232.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7066)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 715)
[M::mem_pestat] mean and std.dev: (258.94, 133.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 902)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 558, 1182)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3206)
[M::mem_pestat] mean and std.dev: (732.29, 666.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4218)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 294, 1270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3312)
[M::mem_pestat] mean and std.dev: (581.67, 545.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4333)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704974 reads in 219.090 CPU sec, 6.985 real sec
[M::mem_process_seqs] Processed 702164 reads in 143.394 CPU sec, 4.561 real sec
sorting block 80, #reads = 1068343 mem = 536879191 peak = 1163698176
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 285091, 24, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 342, 1009)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2653)
[M::mem_pestat] mean and std.dev: (589.83, 610.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3475)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 229, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 721)
[M::mem_pestat] mean and std.dev: (259.86, 134.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 910)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 909, 1627)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4547)
[M::mem_pestat] mean and std.dev: (835.43, 873.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6007)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 279, 429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 789)
[M::mem_pestat] mean and std.dev: (284.27, 122.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 969)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699346 sequences (100000240 bp) in 2.773 CPU sec, 2.904 real sec...
[M::process] read 699108 sequences (100000199 bp) in 2.041 CPU sec, 2.041 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 285621, 27, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 313, 1507)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4165)
[M::mem_pestat] mean and std.dev: (719.50, 770.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5494)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 740)
[M::mem_pestat] mean and std.dev: (265.84, 136.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 934)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 722, 1958)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5484)
[M::mem_pestat] mean and std.dev: (921.35, 943.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7247)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (315, 426, 1242)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3096)
[M::mem_pestat] mean and std.dev: (697.70, 640.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4023)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701980 reads in 213.523 CPU sec, 6.810 real sec
[M::mem_process_seqs] Processed 700014 reads in 142.389 CPU sec, 4.524 real sec
sorting block 81, #reads = 1071753 mem = 536878932 peak = 1163698176
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 284710, 30, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (318, 692, 1041)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2487)
[M::mem_pestat] mean and std.dev: (678.90, 496.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3210)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 237, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 747)
[M::mem_pestat] mean and std.dev: (267.96, 138.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 943)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 917, 1357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3559)
[M::mem_pestat] mean and std.dev: (952.10, 1078.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5266)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (374, 686, 1487)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3713)
[M::mem_pestat] mean and std.dev: (864.40, 679.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4826)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699952 sequences (100000046 bp) in 2.477 CPU sec, 2.619 real sec...
[M::process] read 699474 sequences (100000114 bp) in 1.614 CPU sec, 1.620 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 285292, 32, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (128, 211, 1972)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5660)
[M::mem_pestat] mean and std.dev: (982.38, 1230.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7504)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 238, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (268.70, 138.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 947)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (253, 709, 1793)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4873)
[M::mem_pestat] mean and std.dev: (1028.12, 989.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6413)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 394, 748)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1734)
[M::mem_pestat] mean and std.dev: (461.11, 324.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2227)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699346 reads in 205.798 CPU sec, 6.632 real sec
sorting block 82, #reads = 1071738 mem = 536879653 peak = 1163698176
[M::mem_process_seqs] Processed 699108 reads in 132.585 CPU sec, 4.248 real sec
sorting block 83, #reads = 1072253 mem = 536879997 peak = 1163698176
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 285790, 22, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 511, 925)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2351)
[M::mem_pestat] mean and std.dev: (611.48, 517.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3064)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 234, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 733)
[M::mem_pestat] mean and std.dev: (264.47, 136.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 925)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (49, 217, 532)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1498)
[M::mem_pestat] mean and std.dev: (276.47, 293.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1981)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 238, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1050)
[M::mem_pestat] mean and std.dev: (247.44, 107.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1339)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699112 sequences (100000205 bp) in 2.885 CPU sec, 3.027 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 284833, 24, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 240, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 982)
[M::mem_pestat] mean and std.dev: (299.00, 205.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1252)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 734)
[M::mem_pestat] mean and std.dev: (265.73, 136.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 926)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (102, 549, 1115)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3141)
[M::mem_pestat] mean and std.dev: (629.17, 727.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4154)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 364, 789)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1903)
[M::mem_pestat] mean and std.dev: (476.20, 323.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2460)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699838 sequences (100000155 bp) in 2.002 CPU sec, 2.003 real sec...
[M::mem_process_seqs] Processed 699952 reads in 197.602 CPU sec, 6.297 real sec
[M::mem_process_seqs] Processed 699474 reads in 132.853 CPU sec, 4.490 real sec
sorting block 84, #reads = 1075538 mem = 536880821 peak = 1163698176
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 284997, 29, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 543, 1362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3608)
[M::mem_pestat] mean and std.dev: (873.76, 730.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4731)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 236, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 738)
[M::mem_pestat] mean and std.dev: (266.54, 137.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 931)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (376, 913, 2913)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7987)
[M::mem_pestat] mean and std.dev: (1237.21, 1199.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10524)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 225, 872)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2174)
[M::mem_pestat] mean and std.dev: (453.30, 377.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2825)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699746 sequences (100000138 bp) in 2.962 CPU sec, 3.117 real sec...
[M::process] read 699946 sequences (100000120 bp) in 1.967 CPU sec, 1.970 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 285346, 24, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 426, 1121)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2949)
[M::mem_pestat] mean and std.dev: (742.03, 703.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3863)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 734)
[M::mem_pestat] mean and std.dev: (265.50, 136.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 926)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (444, 579, 1455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3477)
[M::mem_pestat] mean and std.dev: (611.16, 438.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4488)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (267, 598, 1694)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4548)
[M::mem_pestat] mean and std.dev: (900.61, 836.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5975)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699112 reads in 198.358 CPU sec, 6.584 real sec
[M::mem_process_seqs] Processed 699838 reads in 134.583 CPU sec, 4.272 real sec
sorting block 85, #reads = 1074813 mem = 536886573 peak = 1163698176
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 284799, 21, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 315, 791)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1929)
[M::mem_pestat] mean and std.dev: (440.82, 409.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2498)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 234, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 731)
[M::mem_pestat] mean and std.dev: (264.52, 136.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 922)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (345, 1079, 4815)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13755)
[M::mem_pestat] mean and std.dev: (2419.86, 2290.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 18225)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (282, 641, 1067)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2637)
[M::mem_pestat] mean and std.dev: (721.75, 490.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3422)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700972 sequences (100000103 bp) in 3.243 CPU sec, 3.368 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 284304, 21, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 400, 1569)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4401)
[M::mem_pestat] mean and std.dev: (564.00, 562.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5817)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 234, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 733)
[M::mem_pestat] mean and std.dev: (264.56, 136.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 925)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (342, 626, 1407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3537)
[M::mem_pestat] mean and std.dev: (545.47, 407.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4602)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (287, 516, 1637)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4337)
[M::mem_pestat] mean and std.dev: (790.90, 720.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5687)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697084 sequences (100000060 bp) in 1.957 CPU sec, 1.962 real sec...
[M::mem_process_seqs] Processed 699746 reads in 213.011 CPU sec, 6.861 real sec
sorting block 86, #reads = 1074285 mem = 536877964 peak = 1163698176
[M::mem_process_seqs] Processed 699946 reads in 141.623 CPU sec, 4.611 real sec
sorting block 87, #reads = 1070713 mem = 536878430 peak = 1163698176
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 284781, 26, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 311, 735)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1789)
[M::mem_pestat] mean and std.dev: (402.05, 348.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2316)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 231, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 723)
[M::mem_pestat] mean and std.dev: (261.58, 135.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 912)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (125, 393, 1176)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3278)
[M::mem_pestat] mean and std.dev: (689.88, 812.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4329)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 441, 990)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2700)
[M::mem_pestat] mean and std.dev: (570.75, 562.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3555)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697222 sequences (100000202 bp) in 2.804 CPU sec, 2.945 real sec...
[M::process] read 696722 sequences (100000129 bp) in 1.846 CPU sec, 1.853 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 283292, 28, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 430, 783)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1939)
[M::mem_pestat] mean and std.dev: (422.69, 269.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2517)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 243, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (274.74, 142.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 966)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (81, 336, 1156)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3306)
[M::mem_pestat] mean and std.dev: (526.12, 614.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4381)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 347, 869)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2163)
[M::mem_pestat] mean and std.dev: (488.32, 409.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2810)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700972 reads in 215.356 CPU sec, 6.970 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 283710, 16, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 328, 542)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1170)
[M::mem_pestat] mean and std.dev: (393.21, 268.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1484)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 242, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 759)
[M::process] read 696738 sequences (100000032 bp) in 2.120 CPU sec, 2.124 real sec...
[M::mem_pestat] mean and std.dev: (273.34, 141.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 958)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 718, 1240)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3328)
[M::mem_pestat] mean and std.dev: (524.15, 376.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4372)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 394, 594)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1418)
[M::mem_pestat] mean and std.dev: (373.27, 256.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1830)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697222 reads in 116.342 CPU sec, 3.770 real sec
sorting block 88, #reads = 1066480 mem = 536877680 peak = 1163698176
[M::mem_process_seqs] Processed 697084 reads in 295.115 CPU sec, 9.491 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 283841, 27, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 293, 727)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1765)
[M::mem_pestat] mean and std.dev: (506.12, 464.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2364)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 769)
[M::mem_pestat] mean and std.dev: (276.25, 144.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 971)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (446, 1333, 1588)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3872)
[M::mem_pestat] mean and std.dev: (961.16, 706.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5014)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 354, 429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 903)
[M::mem_pestat] mean and std.dev: (357.89, 215.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1219)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 89, #reads = 1073202 mem = 536879424 peak = 1163698176
[M::process] read 696418 sequences (100000215 bp) in 2.999 CPU sec, 3.384 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 283939, 20, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 294, 1179)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3251)
[M::mem_pestat] mean and std.dev: (407.74, 400.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4287)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 775)
[M::mem_pestat] mean and std.dev: (276.81, 145.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 979)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (452, 684, 4221)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11759)
[M::mem_pestat] mean and std.dev: (1887.55, 2259.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 15528)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 412, 1330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3620)
[M::mem_pestat] mean and std.dev: (739.32, 661.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4765)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696722 reads in 218.188 CPU sec, 6.953 real sec
[M::mem_process_seqs] Processed 696738 reads in 131.983 CPU sec, 4.175 real sec
[M::process] read 696130 sequences (100000006 bp) in 2.301 CPU sec, 2.390 real sec...
sorting block 90, #reads = 1072160 mem = 536879393 peak = 1163698176
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 283407, 17, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 411, 1016)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2572)
[M::mem_pestat] mean and std.dev: (735.88, 725.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3637)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 246, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 776)
[M::mem_pestat] mean and std.dev: (277.86, 145.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 980)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (268, 311, 829)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1951)
[M::mem_pestat] mean and std.dev: (502.06, 426.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2512)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 349, 506)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1038)
[M::mem_pestat] mean and std.dev: (381.15, 216.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1304)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698850 sequences (100000131 bp) in 2.885 CPU sec, 3.079 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 283184, 25, 9)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (277, 642, 2068)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5650)
[M::mem_pestat] mean and std.dev: (1141.26, 1103.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7441)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 245, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (277.40, 145.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 976)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (468, 1589, 2636)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6972)
[M::mem_pestat] mean and std.dev: (1649.54, 1405.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9140)
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::process] read 701028 sequences (100000080 bp) in 2.019 CPU sec, 2.016 real sec...
[M::mem_process_seqs] Processed 696418 reads in 200.635 CPU sec, 6.408 real sec
[M::mem_process_seqs] Processed 696130 reads in 137.398 CPU sec, 4.364 real sec
sorting block 91, #reads = 1073262 mem = 536879501 peak = 1163698176
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 283728, 17, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 431, 1156)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3082)
[M::mem_pestat] mean and std.dev: (706.23, 705.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4045)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 237, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (269.39, 141.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 947)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (285, 700, 1005)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2445)
[M::mem_pestat] mean and std.dev: (668.88, 497.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3165)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 409, 897)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2301)
[M::mem_pestat] mean and std.dev: (536.52, 457.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3003)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698932 sequences (100000138 bp) in 2.904 CPU sec, 3.081 real sec...
[M::process] read 698884 sequences (100000224 bp) in 2.043 CPU sec, 2.046 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 285592, 21, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 308, 836)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2082)
[M::mem_pestat] mean and std.dev: (521.73, 488.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2705)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 231, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 732)
[M::mem_pestat] mean and std.dev: (263.86, 139.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 924)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (393, 1007, 4019)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11271)
[M::mem_pestat] mean and std.dev: (1799.05, 1990.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14897)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 335, 646)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1522)
[M::mem_pestat] mean and std.dev: (402.08, 293.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1960)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698850 reads in 214.357 CPU sec, 6.832 real sec
sorting block 92, #reads = 1070054 mem = 536880374 peak = 1163698176
[M::mem_process_seqs] Processed 701028 reads in 133.824 CPU sec, 4.521 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 284851, 35, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 388, 1058)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2808)
[M::mem_pestat] mean and std.dev: (604.18, 605.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3683)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 238, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 759)
[M::mem_pestat] mean and std.dev: (270.96, 142.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 959)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (289, 739, 1191)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2995)
[M::mem_pestat] mean and std.dev: (698.15, 471.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3897)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (301, 372, 607)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1219)
[M::mem_pestat] mean and std.dev: (376.85, 183.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1525)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 93, #reads = 1068413 mem = 536878090 peak = 1163698176
[M::process] read 697260 sequences (100000229 bp) in 2.674 CPU sec, 2.837 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 285350, 27, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 243, 514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1170)
[M::mem_pestat] mean and std.dev: (280.63, 180.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1498)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 240, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (271.75, 142.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 960)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (440, 1349, 1349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3167)
[M::mem_pestat] mean and std.dev: (852.91, 664.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4076)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 321, 581)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1309)
[M::mem_pestat] mean and std.dev: (446.48, 314.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1706)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695850 sequences (100000186 bp) in 1.964 CPU sec, 1.974 real sec...
[M::mem_process_seqs] Processed 698932 reads in 189.986 CPU sec, 6.316 real sec
[M::mem_process_seqs] Processed 698884 reads in 124.328 CPU sec, 3.936 real sec
sorting block 94, #reads = 1078536 mem = 536878985 peak = 1163698176
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 284469, 28, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 329, 787)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1967)
[M::mem_pestat] mean and std.dev: (514.93, 441.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2557)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 244, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 774)
[M::mem_pestat] mean and std.dev: (275.74, 143.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 978)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (546, 702, 2360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5988)
[M::mem_pestat] mean and std.dev: (1361.33, 1552.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7802)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (272, 383, 725)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1631)
[M::mem_pestat] mean and std.dev: (407.38, 236.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2084)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695976 sequences (100000299 bp) in 2.759 CPU sec, 2.996 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 283893, 29, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 524, 1298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3366)
[M::mem_pestat] mean and std.dev: (734.21, 602.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4400)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 250, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 786)
[M::mem_pestat] mean and std.dev: (280.22, 145.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 993)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (270, 852, 3850)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11010)
[M::mem_pestat] mean and std.dev: (2182.10, 2286.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14590)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 306, 868)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2288)
[M::mem_pestat] mean and std.dev: (423.51, 394.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2998)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697260 reads in 184.635 CPU sec, 5.921 real sec
[M::process] read 696196 sequences (100000266 bp) in 1.962 CPU sec, 2.037 real sec...
[M::mem_process_seqs] Processed 695850 reads in 125.714 CPU sec, 4.027 real sec
sorting block 95, #reads = 1077196 mem = 536879391 peak = 1163698176
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 284443, 26, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 214, 1166)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3196)
[M::mem_pestat] mean and std.dev: (638.96, 704.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4211)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 250, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 792)
[M::mem_pestat] mean and std.dev: (280.94, 146.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1001)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 387, 1633)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4585)
[M::mem_pestat] mean and std.dev: (958.85, 1066.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6061)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (269, 408, 666)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1460)
[M::mem_pestat] mean and std.dev: (423.46, 259.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1857)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698090 sequences (100000301 bp) in 2.533 CPU sec, 2.872 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 284270, 21, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (274, 373, 651)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1405)
[M::mem_pestat] mean and std.dev: (488.94, 339.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1847)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 249, 375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 797)
[M::mem_pestat] mean and std.dev: (280.93, 147.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1008)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 280, 2359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6549)
[M::mem_pestat] mean and std.dev: (1069.19, 1459.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8644)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 540, 1037)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2697)
[M::mem_pestat] mean and std.dev: (631.19, 574.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3527)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699580 sequences (100000276 bp) in 2.094 CPU sec, 2.130 real sec...
[M::mem_process_seqs] Processed 695976 reads in 190.856 CPU sec, 6.383 real sec
[M::mem_process_seqs] Processed 696196 reads in 126.176 CPU sec, 4.007 real sec
sorting block 96, #reads = 1076744 mem = 536880972 peak = 1163698176
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 284994, 23, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (314, 483, 911)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2105)
[M::mem_pestat] mean and std.dev: (508.21, 375.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2702)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 241, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (272.48, 141.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 961)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (408, 1010, 2231)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5877)
[M::mem_pestat] mean and std.dev: (1248.76, 1274.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7700)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 303, 864)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2166)
[M::mem_pestat] mean and std.dev: (396.62, 307.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2817)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697622 sequences (100000267 bp) in 2.859 CPU sec, 3.337 real sec...
sorting block 97, #reads = 1076819 mem = 536878154 peak = 1163698176
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 285469, 19, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (268, 370, 582)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1210)
[M::mem_pestat] mean and std.dev: (404.88, 204.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1524)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 234, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 737)
[M::mem_pestat] mean and std.dev: (265.90, 138.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 930)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (591, 688, 1223)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2487)
[M::mem_pestat] mean and std.dev: (695.19, 373.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3119)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 435, 1559)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4183)
[M::mem_pestat] mean and std.dev: (955.14, 1132.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5495)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698090 reads in 189.780 CPU sec, 6.086 real sec
[M::process] read 697454 sequences (100000226 bp) in 2.013 CPU sec, 2.025 real sec...
[M::mem_process_seqs] Processed 699580 reads in 129.636 CPU sec, 4.240 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 284622, 27, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 299, 678)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1590)
[M::mem_pestat] mean and std.dev: (367.94, 263.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2046)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 243, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (274.57, 143.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 977)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (821, 899, 1565)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3053)
[M::mem_pestat] mean and std.dev: (982.23, 592.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3797)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 342, 627)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1517)
[M::mem_pestat] mean and std.dev: (428.83, 305.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1962)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 98, #reads = 1078581 mem = 536879434 peak = 1163698176
[M::process] read 696854 sequences (100000128 bp) in 2.785 CPU sec, 3.304 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 284268, 34, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 299, 773)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2005)
[M::mem_pestat] mean and std.dev: (413.50, 441.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2621)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 242, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 768)
[M::mem_pestat] mean and std.dev: (274.56, 143.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 970)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (434, 783, 1044)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2264)
[M::mem_pestat] mean and std.dev: (697.38, 379.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2874)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 295, 584)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1366)
[M::mem_pestat] mean and std.dev: (367.06, 247.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1757)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696344 sequences (100000053 bp) in 1.874 CPU sec, 1.907 real sec...
[M::mem_process_seqs] Processed 697622 reads in 197.422 CPU sec, 6.502 real sec
[M::mem_process_seqs] Processed 697454 reads in 132.788 CPU sec, 4.285 real sec
sorting block 99, #reads = 1077708 mem = 536877737 peak = 1163698176
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 284502, 23, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 357, 513)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1173)
[M::mem_pestat] mean and std.dev: (332.82, 163.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1503)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 246, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 781)
[M::mem_pestat] mean and std.dev: (277.70, 145.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 987)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (364, 597, 2386)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6430)
[M::mem_pestat] mean and std.dev: (1154.00, 1209.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8452)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 349, 804)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1926)
[M::mem_pestat] mean and std.dev: (409.00, 320.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2487)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696308 sequences (100000252 bp) in 2.953 CPU sec, 3.151 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 283540, 22, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (279, 543, 1000)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2442)
[M::mem_pestat] mean and std.dev: (631.44, 387.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3163)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 246, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 782)
[M::mem_pestat] mean and std.dev: (278.46, 145.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 988)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 475, 1369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3821)
[M::mem_pestat] mean and std.dev: (803.48, 922.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5047)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 302, 628)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1522)
[M::mem_pestat] mean and std.dev: (319.44, 176.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1969)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696854 reads in 194.884 CPU sec, 6.288 real sec
[M::process] read 697846 sequences (100000276 bp) in 2.342 CPU sec, 2.450 real sec...
[M::mem_process_seqs] Processed 696344 reads in 133.723 CPU sec, 4.269 real sec
sorting block 100, #reads = 1074235 mem = 536878253 peak = 1163698176
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 283262, 28, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 477, 1069)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2811)
[M::mem_pestat] mean and std.dev: (652.46, 581.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3682)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 246, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 778)
[M::mem_pestat] mean and std.dev: (277.87, 145.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 983)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (406, 839, 1958)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5062)
[M::mem_pestat] mean and std.dev: (1241.57, 1183.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6614)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (279, 398, 547)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1083)
[M::mem_pestat] mean and std.dev: (389.58, 174.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1351)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697266 sequences (100000142 bp) in 2.622 CPU sec, 3.151 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 283577, 26, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 258, 1205)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3223)
[M::mem_pestat] mean and std.dev: (569.41, 645.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4232)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 240, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 752)
[M::mem_pestat] mean and std.dev: (270.74, 140.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 526, 770)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1962)
[M::mem_pestat] mean and std.dev: (504.21, 420.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2558)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 367, 987)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2481)
[M::mem_pestat] mean and std.dev: (520.63, 426.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3228)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696890 sequences (100000042 bp) in 1.842 CPU sec, 1.858 real sec...
[M::mem_process_seqs] Processed 696308 reads in 210.296 CPU sec, 7.003 real sec
sorting block 101, #reads = 1074425 mem = 536879496 peak = 1163698176
[M::mem_process_seqs] Processed 697846 reads in 146.893 CPU sec, 4.773 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 283771, 20, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 270, 411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 831)
[M::mem_pestat] mean and std.dev: (306.00, 159.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1041)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 241, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (272.80, 142.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (75, 324, 1811)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5283)
[M::mem_pestat] mean and std.dev: (702.47, 855.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7019)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (366, 586, 1812)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4704)
[M::mem_pestat] mean and std.dev: (993.20, 905.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6150)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 102, #reads = 1071237 mem = 536878670 peak = 1166696448
[M::process] read 697154 sequences (100000020 bp) in 2.617 CPU sec, 3.122 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (18, 283619, 22, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 307, 666)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1682)
[M::mem_pestat] mean and std.dev: (444.83, 344.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2190)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 243, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 769)
[M::mem_pestat] mean and std.dev: (275.47, 144.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 971)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 512, 757)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1919)
[M::mem_pestat] mean and std.dev: (438.89, 405.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2500)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 478, 1527)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4095)
[M::mem_pestat] mean and std.dev: (716.90, 661.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5379)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697242 sequences (100000203 bp) in 2.088 CPU sec, 2.102 real sec...
[M::mem_process_seqs] Processed 697266 reads in 207.995 CPU sec, 6.766 real sec
[M::mem_process_seqs] Processed 696890 reads in 135.907 CPU sec, 4.343 real sec
sorting block 103, #reads = 1071227 mem = 536881974 peak = 1166696448
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 283596, 20, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 445, 1180)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3050)
[M::mem_pestat] mean and std.dev: (662.37, 574.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3985)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 242, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 759)
[M::mem_pestat] mean and std.dev: (273.44, 142.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 958)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (343, 878, 2187)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5875)
[M::mem_pestat] mean and std.dev: (876.39, 848.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7719)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 302, 1485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4001)
[M::mem_pestat] mean and std.dev: (674.32, 682.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5259)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697150 sequences (100000025 bp) in 2.999 CPU sec, 3.284 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 283571, 15, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 632, 1099)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2885)
[M::mem_pestat] mean and std.dev: (618.53, 490.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3778)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 240, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (272.21, 142.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 950)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (396, 577, 1876)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4836)
[M::mem_pestat] mean and std.dev: (1162.87, 1218.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6316)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 281, 581)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1375)
[M::mem_pestat] mean and std.dev: (386.98, 309.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1772)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698098 sequences (100000153 bp) in 1.965 CPU sec, 2.013 real sec...
[M::mem_process_seqs] Processed 697154 reads in 210.185 CPU sec, 6.757 real sec
[M::mem_process_seqs] Processed 697242 reads in 139.608 CPU sec, 4.500 real sec
sorting block 104, #reads = 1073926 mem = 536880856 peak = 1166696448
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 283767, 24, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 276, 486)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1102)
[M::mem_pestat] mean and std.dev: (364.41, 249.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1410)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 240, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 752)
[M::mem_pestat] mean and std.dev: (271.65, 141.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (269, 979, 2096)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5750)
[M::mem_pestat] mean and std.dev: (1135.78, 1234.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7577)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (294, 419, 646)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1350)
[M::mem_pestat] mean and std.dev: (433.22, 262.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1702)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699350 sequences (100000281 bp) in 3.009 CPU sec, 3.249 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 283643, 23, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 341, 743)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1901)
[M::mem_pestat] mean and std.dev: (432.63, 434.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2480)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 238, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 739)
[M::mem_pestat] mean and std.dev: (268.23, 139.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 932)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 556, 1587)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4271)
[M::mem_pestat] mean and std.dev: (530.21, 515.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5613)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (391, 693, 2755)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7483)
[M::mem_pestat] mean and std.dev: (1708.65, 1961.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9847)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704276 sequences (100000102 bp) in 2.141 CPU sec, 2.221 real sec...
[M::mem_process_seqs] Processed 697150 reads in 215.887 CPU sec, 6.985 real sec
sorting block 105, #reads = 1073548 mem = 536885776 peak = 1166696448
[M::mem_process_seqs] Processed 698098 reads in 148.077 CPU sec, 4.732 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 284351, 29, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 333, 717)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1729)
[M::mem_pestat] mean and std.dev: (448.05, 377.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2235)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 234, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 728)
[M::mem_pestat] mean and std.dev: (264.59, 137.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 918)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (255, 874, 1771)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4803)
[M::mem_pestat] mean and std.dev: (1021.41, 919.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6319)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (288, 448, 1545)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4059)
[M::mem_pestat] mean and std.dev: (766.23, 715.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5316)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 106, #reads = 1071660 mem = 536879495 peak = 1168121856
[M::process] read 700710 sequences (100000123 bp) in 2.928 CPU sec, 3.232 real sec...
[M::process] read 699666 sequences (100000142 bp) in 1.854 CPU sec, 1.902 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 286237, 19, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (263, 514, 783)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1823)
[M::mem_pestat] mean and std.dev: (456.92, 292.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2343)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 222, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697)
[M::mem_pestat] mean and std.dev: (253.74, 132.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 421, 1113)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3025)
[M::mem_pestat] mean and std.dev: (608.37, 519.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3981)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 545, 1463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3881)
[M::mem_pestat] mean and std.dev: (935.70, 849.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5090)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699350 reads in 228.989 CPU sec, 7.363 real sec
[M::mem_process_seqs] Processed 704276 reads in 152.858 CPU sec, 5.059 real sec
sorting block 107, #reads = 1066258 mem = 536878891 peak = 1168121856
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 285309, 22, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 455, 1142)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3112)
[M::mem_pestat] mean and std.dev: (751.17, 824.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4097)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 232, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 739)
[M::mem_pestat] mean and std.dev: (265.53, 139.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 933)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (642, 1056, 1482)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3162)
[M::mem_pestat] mean and std.dev: (1109.45, 773.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4205)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 244, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1110)
[M::mem_pestat] mean and std.dev: (235.91, 118.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1430)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698808 sequences (100000248 bp) in 3.047 CPU sec, 3.266 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 284861, 28, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 440, 1285)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3475)
[M::mem_pestat] mean and std.dev: (681.90, 758.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4570)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 237, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (269.63, 141.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 955)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (518, 589, 742)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (70, 1190)
[M::mem_pestat] mean and std.dev: (594.32, 169.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1414)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 309, 1724)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4772)
[M::mem_pestat] mean and std.dev: (858.77, 959.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6296)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697258 sequences (100000073 bp) in 1.890 CPU sec, 1.888 real sec...
[M::mem_process_seqs] Processed 700710 reads in 202.621 CPU sec, 6.629 real sec
[M::mem_process_seqs] Processed 699666 reads in 135.192 CPU sec, 4.305 real sec
sorting block 108, #reads = 1071875 mem = 536883415 peak = 1168121856
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 284852, 21, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 465, 2024)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5650)
[M::mem_pestat] mean and std.dev: (1216.49, 1300.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7463)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 239, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (270.72, 141.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 956)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 410, 851)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2087)
[M::mem_pestat] mean and std.dev: (524.00, 351.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2705)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 393, 1144)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2960)
[M::mem_pestat] mean and std.dev: (816.61, 813.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4069)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696840 sequences (100000045 bp) in 3.060 CPU sec, 3.345 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 284350, 26, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (495, 935, 965)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1905)
[M::mem_pestat] mean and std.dev: (719.50, 331.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2375)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 246, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 784)
[M::mem_pestat] mean and std.dev: (277.58, 144.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 991)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (55, 516, 1242)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3616)
[M::mem_pestat] mean and std.dev: (663.58, 745.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4803)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (460, 747, 882)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1726)
[M::mem_pestat] mean and std.dev: (621.31, 308.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2148)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697344 sequences (100000278 bp) in 1.909 CPU sec, 1.910 real sec...
[M::mem_process_seqs] Processed 698808 reads in 198.715 CPU sec, 6.347 real sec
sorting block 109, #reads = 1074260 mem = 536876594 peak = 1168121856
[M::mem_process_seqs] Processed 697258 reads in 138.170 CPU sec, 4.696 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 284329, 21, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 425, 797)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1941)
[M::mem_pestat] mean and std.dev: (481.72, 315.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2513)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 247, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 785)
[M::mem_pestat] mean and std.dev: (278.80, 145.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 992)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (363, 733, 1166)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2772)
[M::mem_pestat] mean and std.dev: (799.81, 434.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3575)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 414, 1456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3894)
[M::mem_pestat] mean and std.dev: (691.90, 655.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5113)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 110, #reads = 1072027 mem = 536881110 peak = 1168121856
[M::process] read 697488 sequences (100000130 bp) in 2.836 CPU sec, 3.149 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 284113, 23, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 798, 2673)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7673)
[M::mem_pestat] mean and std.dev: (1336.17, 1317.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10173)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 244, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 777)
[M::mem_pestat] mean and std.dev: (276.31, 144.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 982)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (302, 636, 1269)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3203)
[M::mem_pestat] mean and std.dev: (817.10, 729.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4170)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 487, 1810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4976)
[M::mem_pestat] mean and std.dev: (866.64, 828.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6559)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696402 sequences (100000005 bp) in 2.070 CPU sec, 2.081 real sec...
[M::mem_process_seqs] Processed 696840 reads in 206.071 CPU sec, 6.888 real sec
[M::mem_process_seqs] Processed 697344 reads in 135.432 CPU sec, 4.322 real sec
sorting block 111, #reads = 1072697 mem = 536881226 peak = 1168121856
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 284910, 19, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (297, 464, 899)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2103)
[M::mem_pestat] mean and std.dev: (583.15, 455.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2705)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 242, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (272.14, 140.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 953)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (462, 526, 828)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1560)
[M::mem_pestat] mean and std.dev: (554.11, 370.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2037)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 361, 729)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1769)
[M::mem_pestat] mean and std.dev: (452.54, 359.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2289)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695600 sequences (100000037 bp) in 2.854 CPU sec, 3.035 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 283883, 24, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (267, 327, 680)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1506)
[M::mem_pestat] mean and std.dev: (410.19, 257.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1919)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 246, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (276.92, 143.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 976)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (497, 791, 2089)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5273)
[M::mem_pestat] mean and std.dev: (707.63, 510.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6865)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 443, 828)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2106)
[M::mem_pestat] mean and std.dev: (514.85, 450.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2745)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696044 sequences (100000273 bp) in 1.929 CPU sec, 1.939 real sec...
[M::mem_process_seqs] Processed 697488 reads in 201.061 CPU sec, 6.429 real sec
[M::mem_process_seqs] Processed 696402 reads in 136.660 CPU sec, 4.343 real sec
sorting block 112, #reads = 1074007 mem = 536878304 peak = 1168121856
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 283220, 38, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 448, 933)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2355)
[M::mem_pestat] mean and std.dev: (560.52, 460.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3066)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 774)
[M::mem_pestat] mean and std.dev: (277.93, 142.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 977)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (43, 663, 1609)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4741)
[M::mem_pestat] mean and std.dev: (860.61, 819.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6307)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 382, 1115)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2923)
[M::mem_pestat] mean and std.dev: (485.52, 371.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3827)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695742 sequences (100000265 bp) in 3.459 CPU sec, 3.701 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 282938, 19, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 411, 537)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1177)
[M::mem_pestat] mean and std.dev: (384.84, 235.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1497)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 247, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (275.77, 140.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 964)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 610, 1333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3615)
[M::mem_pestat] mean and std.dev: (699.33, 680.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4756)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 363, 1196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3166)
[M::mem_pestat] mean and std.dev: (641.73, 478.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4151)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695528 sequences (100000134 bp) in 2.104 CPU sec, 2.115 real sec...
[M::mem_process_seqs] Processed 695600 reads in 203.505 CPU sec, 6.501 real sec
sorting block 113, #reads = 1073740 mem = 536882465 peak = 1168121856
[M::mem_process_seqs] Processed 696044 reads in 150.229 CPU sec, 4.801 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 282832, 30, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 211, 803)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2095)
[M::mem_pestat] mean and std.dev: (422.86, 480.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2741)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 759)
[M::mem_pestat] mean and std.dev: (275.33, 139.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 957)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (334, 779, 1786)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4690)
[M::mem_pestat] mean and std.dev: (999.22, 924.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6142)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 336, 516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1108)
[M::mem_pestat] mean and std.dev: (349.94, 187.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1404)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 114, #reads = 1071122 mem = 536878703 peak = 1168121856
[M::process] read 695232 sequences (100000055 bp) in 3.093 CPU sec, 3.275 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 282606, 19, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (260, 449, 1297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3371)
[M::mem_pestat] mean and std.dev: (626.71, 600.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4408)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 248, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (275.46, 139.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (31, 669, 1221)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3601)
[M::mem_pestat] mean and std.dev: (645.82, 598.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4791)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 539, 1286)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3422)
[M::mem_pestat] mean and std.dev: (708.44, 603.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4490)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695008 sequences (100000252 bp) in 2.050 CPU sec, 2.053 real sec...
[M::mem_process_seqs] Processed 695742 reads in 203.346 CPU sec, 6.485 real sec
[M::mem_process_seqs] Processed 695528 reads in 137.532 CPU sec, 4.362 real sec
sorting block 115, #reads = 1070834 mem = 536878836 peak = 1168121856
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 282888, 16, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (270, 384, 814)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1902)
[M::mem_pestat] mean and std.dev: (538.32, 458.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2446)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 248, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (275.27, 138.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 950)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (726, 1426, 3323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8517)
[M::mem_pestat] mean and std.dev: (2018.06, 2162.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11114)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (302, 374, 1203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3005)
[M::mem_pestat] mean and std.dev: (614.91, 550.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3906)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694912 sequences (100000073 bp) in 2.867 CPU sec, 3.025 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 282625, 25, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 306, 553)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1367)
[M::mem_pestat] mean and std.dev: (382.12, 290.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1774)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 248, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (275.03, 138.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 946)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (304, 479, 1501)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3895)
[M::mem_pestat] mean and std.dev: (1001.32, 1032.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5131)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 510, 650)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1474)
[M::mem_pestat] mean and std.dev: (440.28, 217.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1886)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695192 sequences (100000185 bp) in 1.932 CPU sec, 1.939 real sec...
[M::mem_process_seqs] Processed 695232 reads in 193.062 CPU sec, 6.156 real sec
[M::mem_process_seqs] Processed 695008 reads in 130.192 CPU sec, 4.140 real sec
sorting block 116, #reads = 1072266 mem = 536880648 peak = 1168121856
[M::process] read 695044 sequences (100000076 bp) in 3.032 CPU sec, 3.247 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 282846, 22, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (367, 501, 594)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1048)
[M::mem_pestat] mean and std.dev: (393.78, 156.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1275)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 246, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 747)
[M::mem_pestat] mean and std.dev: (273.24, 137.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 941)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (291, 829, 2738)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7632)
[M::mem_pestat] mean and std.dev: (1381.35, 1522.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10079)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 503, 911)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2261)
[M::mem_pestat] mean and std.dev: (502.88, 391.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2936)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694828 sequences (100000191 bp) in 2.085 CPU sec, 2.092 real sec...
[M::mem_process_seqs] Processed 695192 reads in 112.465 CPU sec, 3.564 real sec
sorting block 117, #reads = 1073114 mem = 536879437 peak = 1168121856
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 282951, 21, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (275, 857, 1399)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3647)
[M::mem_pestat] mean and std.dev: (954.27, 817.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4771)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 247, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 745)
[M::mem_pestat] mean and std.dev: (273.79, 137.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 938)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (290, 442, 692)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1496)
[M::mem_pestat] mean and std.dev: (404.89, 252.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1898)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 433, 795)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1893)
[M::mem_pestat] mean and std.dev: (593.93, 432.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2442)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 282937, 35, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (127, 294, 2297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6637)
[M::mem_pestat] mean and std.dev: (814.90, 1053.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8807)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 248, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (275.33, 139.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 946)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (600, 1183, 2482)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6246)
[M::mem_pestat] mean and std.dev: (1534.80, 1105.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8128)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 378, 1664)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4530)
[M::mem_pestat] mean and std.dev: (801.42, 768.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5963)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694912 reads in 297.028 CPU sec, 9.744 real sec
[M::process] read 694740 sequences (100000229 bp) in 2.554 CPU sec, 2.589 real sec...
[M::mem_process_seqs] Processed 695044 reads in 158.033 CPU sec, 5.041 real sec
sorting block 118, #reads = 1073664 mem = 536879616 peak = 1168121856
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 282374, 34, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 310, 547)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1235)
[M::mem_pestat] mean and std.dev: (366.88, 273.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1579)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 249, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (275.21, 138.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 946)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (114, 304, 1730)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4962)
[M::mem_pestat] mean and std.dev: (689.31, 798.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6578)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 299, 499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1103)
[M::mem_pestat] mean and std.dev: (317.88, 212.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1405)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694928 sequences (100000063 bp) in 3.172 CPU sec, 3.324 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 282714, 25, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 541, 2122)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5948)
[M::mem_pestat] mean and std.dev: (966.08, 1123.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7861)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 249, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (275.97, 139.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 951)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (351, 659, 2643)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7227)
[M::mem_pestat] mean and std.dev: (1127.72, 1052.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9519)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (281, 369, 837)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1949)
[M::mem_pestat] mean and std.dev: (474.46, 431.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2505)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694828 reads in 180.546 CPU sec, 5.756 real sec
[M::mem_process_seqs] Processed 694740 reads in 121.107 CPU sec, 3.817 real sec
sorting block 119, #reads = 1074240 mem = 536878502 peak = 1168121856
[M::process] read 695226 sequences (100000167 bp) in 2.672 CPU sec, 2.781 real sec...
[M::process] read 204566 sequences (29357420 bp) in 1.093 CPU sec, 1.161 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 283647, 25, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 351, 695)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1681)
[M::mem_pestat] mean and std.dev: (373.59, 270.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2174)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 248, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (276.38, 140.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 958)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (435, 699, 925)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1905)
[M::mem_pestat] mean and std.dev: (615.70, 366.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2395)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 349, 782)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1926)
[M::mem_pestat] mean and std.dev: (499.05, 359.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2498)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694928 reads in 99.726 CPU sec, 3.290 real sec
sorting block 120, #reads = 1074291 mem = 536878334 peak = 1168121856
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 282736, 15, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 338, 958)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2514)
[M::mem_pestat] mean and std.dev: (429.28, 369.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3292)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 248, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (276.22, 140.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 958)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (417, 1223, 1598)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3960)
[M::mem_pestat] mean and std.dev: (1136.67, 950.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5141)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 610, 2720)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7788)
[M::mem_pestat] mean and std.dev: (1234.81, 1399.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10322)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (11, 83196, 5, 9)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (131, 173, 1721)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4901)
[M::mem_pestat] mean and std.dev: (788.64, 1162.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6491)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 241, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 744)
[M::mem_pestat] mean and std.dev: (270.13, 137.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 938)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::mem_process_seqs] Processed 695226 reads in 146.397 CPU sec, 4.789 real sec
[M::mem_process_seqs] Processed 204566 reads in 52.317 CPU sec, 1.688 real sec
sorting block 121, #reads = 1074462 mem = 536880342 peak = 1168121856
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 130493006
overall: 70016802816 mem 20372.771 user 428.967 sys 684.875 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1136_4GR-T1-TDNA-1_A23MHWWLT4_1.L001\tPU:L001\tSM:1136_4GR-T1-TDNA-1_A23MHWWLT4_1\tLB:1136_4GR-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1136_4GR-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1136_4GR-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 684.915 sec; CPU: 20801.741 sec
sorting block 122, #reads = 487935 mem = 244837671 peak = 1168121856
uniq header count 1
merging 123 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31 max 192
algo: util-sort
license: sentieon:util=1
output file size: 7350087198
output reads: 131581396
bam_mem_sort: 123 calls 72.171 user 0.968 sys 73.611 real
bam_write: 123 calls 49.460 user 2.904 sys 71.759 real
execute: 1 calls 37.018 user 1.632 sys 729.643 real
merge_files: 1 calls 37.005 user 1.598 sys 44.483 real
parse_chunk: 1960 calls 88.119 user 22.188 sys 117.844 real
read_chunk: 5300 calls 42.138 user 35.793 sys 626.671 real
sort_block: 1 calls 27.642 user 35.047 sys 606.327 real
write_chunk: 3338 calls 36.639 user 1.273 sys 43.502 real
overall: 3487584256 mem 1770.677 user 79.107 sys 729.666 real
ls: cannot access '*.cram': No such file or directory