This software is licensed to bgold@natera.com by Sentieon Inc.
cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1136_6G2-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 2154.118 CPU sec, 86.568 real sec
[M::process] read 697074 sequences (100000217 bp) in 1.039 CPU sec, 1.040 real sec...
[M::process] read 693168 sequences (100000233 bp) in 1.300 CPU sec, 1.307 real sec...
[M::process] read 694072 sequences (100000010 bp) in 1.376 CPU sec, 1.385 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 284783, 29, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 326, 759)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1865)
[M::mem_pestat] mean and std.dev: (405.27, 329.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2418)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 254, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 781)
[M::mem_pestat] mean and std.dev: (279.97, 142.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 986)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 1013, 1453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4089)
[M::mem_pestat] mean and std.dev: (886.58, 1026.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5407)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 279, 564)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1354)
[M::mem_pestat] mean and std.dev: (429.55, 362.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1879)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696798 sequences (100000124 bp) in 1.246 CPU sec, 1.266 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 283577, 34, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 432, 691)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1617)
[M::mem_pestat] mean and std.dev: (475.35, 319.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2080)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 269, 392)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 826)
[M::mem_pestat] mean and std.dev: (294.39, 148.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1043)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (524, 817, 1371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3065)
[M::mem_pestat] mean and std.dev: (1054.79, 738.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4010)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (447, 499, 984)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2058)
[M::mem_pestat] mean and std.dev: (669.20, 418.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2595)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (88, 284253, 39, 108)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 268, 577)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1363)
[M::mem_pestat] mean and std.dev: (285.76, 187.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1756)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 267, 391)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 827)
[M::mem_pestat] mean and std.dev: (292.99, 149.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1045)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 659, 2388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6810)
[M::mem_pestat] mean and std.dev: (1020.79, 1494.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9021)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 289, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 973)
[M::mem_pestat] mean and std.dev: (304.43, 162.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1229)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697074 reads in 284.074 CPU sec, 9.191 real sec
[M::mem_process_seqs] Processed 693168 reads in 184.816 CPU sec, 6.056 real sec
[M::mem_process_seqs] Processed 694072 reads in 203.113 CPU sec, 6.647 real sec
sorting block 0, #reads = 1079666 mem = 536881163 peak = 605884416
[M::process] read 696786 sequences (100000225 bp) in 2.110 CPU sec, 2.270 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 285543, 24, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 309, 384)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 776)
[M::mem_pestat] mean and std.dev: (272.34, 113.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 972)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 255, 375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 791)
[M::mem_pestat] mean and std.dev: (281.95, 144.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 999)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (58, 314, 2229)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6571)
[M::mem_pestat] mean and std.dev: (1074.52, 1597.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8742)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 334, 739)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1781)
[M::mem_pestat] mean and std.dev: (360.83, 231.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2302)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697238 sequences (100000039 bp) in 1.341 CPU sec, 1.369 real sec...
[M::process] read 694138 sequences (100000084 bp) in 1.140 CPU sec, 1.139 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 284684, 27, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 392, 1168)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3104)
[M::mem_pestat] mean and std.dev: (696.38, 660.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4072)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 254, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 787)
[M::mem_pestat] mean and std.dev: (281.11, 143.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 994)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (505, 795, 1655)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3955)
[M::mem_pestat] mean and std.dev: (1070.85, 864.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5105)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (275, 422, 1239)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3167)
[M::mem_pestat] mean and std.dev: (602.14, 607.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4131)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696798 reads in 165.430 CPU sec, 5.263 real sec
sorting block 1, #reads = 1079620 mem = 536879342 peak = 821366784
[M::mem_process_seqs] Processed 696786 reads in 106.435 CPU sec, 3.389 real sec
sorting block 2, #reads = 1082268 mem = 536878438 peak = 884527104
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (85, 285168, 26, 84)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 407, 1692)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4534)
[M::mem_pestat] mean and std.dev: (966.74, 1000.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5955)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 252, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 778)
[M::mem_pestat] mean and std.dev: (279.49, 143.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 982)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (490, 596, 879)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1657)
[M::mem_pestat] mean and std.dev: (570.59, 290.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2046)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 426, 1246)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3314)
[M::mem_pestat] mean and std.dev: (698.73, 657.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4348)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693836 sequences (100000130 bp) in 2.651 CPU sec, 2.787 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 284167, 33, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 289, 951)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2447)
[M::mem_pestat] mean and std.dev: (530.76, 512.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3195)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 265, 387)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 817)
[M::mem_pestat] mean and std.dev: (291.15, 148.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1032)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (337, 917, 1588)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4090)
[M::mem_pestat] mean and std.dev: (1071.27, 975.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5341)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (262, 373, 1883)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5125)
[M::mem_pestat] mean and std.dev: (972.78, 1179.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6746)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696776 sequences (100000268 bp) in 1.700 CPU sec, 1.692 real sec...
[M::mem_process_seqs] Processed 697238 reads in 162.692 CPU sec, 5.151 real sec
[M::mem_process_seqs] Processed 694138 reads in 105.988 CPU sec, 3.357 real sec
sorting block 3, #reads = 1083013 mem = 536880488 peak = 884527104
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (107, 284005, 33, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 370, 763)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1891)
[M::mem_pestat] mean and std.dev: (562.38, 476.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2468)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 267, 391)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 827)
[M::mem_pestat] mean and std.dev: (293.37, 149.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1045)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (598, 977, 2954)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7666)
[M::mem_pestat] mean and std.dev: (1480.97, 1496.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10022)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 257, 747)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1821)
[M::mem_pestat] mean and std.dev: (453.14, 387.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2358)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696028 sequences (100000202 bp) in 2.495 CPU sec, 2.632 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 285140, 23, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 421, 941)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2389)
[M::mem_pestat] mean and std.dev: (522.63, 420.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3113)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 253, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 784)
[M::mem_pestat] mean and std.dev: (280.48, 143.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 990)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 690, 1407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3901)
[M::mem_pestat] mean and std.dev: (998.26, 1138.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5554)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 387, 643)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1509)
[M::mem_pestat] mean and std.dev: (447.50, 374.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1945)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695822 sequences (100000111 bp) in 1.729 CPU sec, 1.730 real sec...
[M::mem_process_seqs] Processed 693836 reads in 161.175 CPU sec, 5.113 real sec
[M::mem_process_seqs] Processed 696776 reads in 105.136 CPU sec, 3.325 real sec
sorting block 4, #reads = 1078551 mem = 536881232 peak = 884527104
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 285018, 26, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 252, 818)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2070)
[M::mem_pestat] mean and std.dev: (447.34, 413.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2696)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 257, 378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 798)
[M::mem_pestat] mean and std.dev: (284.47, 145.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1008)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (355, 765, 2432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6586)
[M::mem_pestat] mean and std.dev: (1565.27, 1759.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8663)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 297, 485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1107)
[M::mem_pestat] mean and std.dev: (313.27, 205.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1418)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695914 sequences (100000215 bp) in 2.278 CPU sec, 2.444 real sec...
[M::process] read 693236 sequences (100000038 bp) in 1.323 CPU sec, 1.332 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 284523, 40, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (286, 472, 1179)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2965)
[M::mem_pestat] mean and std.dev: (772.83, 704.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3858)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 257, 376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 792)
[M::mem_pestat] mean and std.dev: (283.72, 145.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1000)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 701, 1303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3581)
[M::mem_pestat] mean and std.dev: (730.87, 572.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4720)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (266, 382, 1251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3221)
[M::mem_pestat] mean and std.dev: (751.72, 715.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4206)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696028 reads in 161.327 CPU sec, 5.142 real sec
sorting block 5, #reads = 1083405 mem = 536878555 peak = 884527104
[M::mem_process_seqs] Processed 695822 reads in 104.751 CPU sec, 3.329 real sec
sorting block 6, #reads = 1081848 mem = 536877177 peak = 884527104
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 284480, 44, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 294, 569)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1369)
[M::mem_pestat] mean and std.dev: (357.32, 244.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1769)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 255, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 786)
[M::mem_pestat] mean and std.dev: (281.79, 143.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 992)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 465, 778)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1932)
[M::mem_pestat] mean and std.dev: (428.70, 309.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2509)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 303, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 908)
[M::mem_pestat] mean and std.dev: (313.40, 149.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1127)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694592 sequences (100000241 bp) in 2.383 CPU sec, 2.546 real sec...
[M::process] read 695936 sequences (100000044 bp) in 1.420 CPU sec, 1.421 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (85, 283642, 32, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 331, 621)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1505)
[M::mem_pestat] mean and std.dev: (387.80, 281.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1947)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 264, 384)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 804)
[M::mem_pestat] mean and std.dev: (290.26, 146.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1014)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (450, 774, 1589)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3867)
[M::mem_pestat] mean and std.dev: (923.10, 734.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5006)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 358, 728)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1742)
[M::mem_pestat] mean and std.dev: (414.97, 346.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2249)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695914 reads in 161.967 CPU sec, 5.147 real sec
[M::mem_process_seqs] Processed 693236 reads in 104.335 CPU sec, 3.321 real sec
sorting block 7, #reads = 1081181 mem = 536883178 peak = 884527104
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 283388, 22, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 260, 787)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2069)
[M::mem_pestat] mean and std.dev: (385.43, 412.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2710)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 259, 375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 783)
[M::mem_pestat] mean and std.dev: (284.55, 143.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 987)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 500, 1958)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5480)
[M::mem_pestat] mean and std.dev: (931.59, 921.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7241)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 374, 726)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1712)
[M::mem_pestat] mean and std.dev: (443.26, 281.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2205)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693048 sequences (100000296 bp) in 2.783 CPU sec, 2.957 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 284876, 19, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 278, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 967)
[M::mem_pestat] mean and std.dev: (300.12, 204.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1223)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 255, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 777)
[M::mem_pestat] mean and std.dev: (281.04, 142.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 980)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (109, 295, 1674)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4804)
[M::mem_pestat] mean and std.dev: (890.05, 1168.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6369)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 380, 537)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1115)
[M::mem_pestat] mean and std.dev: (390.51, 208.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1404)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694838 sequences (100000266 bp) in 1.560 CPU sec, 1.564 real sec...
[M::mem_process_seqs] Processed 694592 reads in 163.863 CPU sec, 5.208 real sec
[M::mem_process_seqs] Processed 695936 reads in 105.954 CPU sec, 3.350 real sec
sorting block 8, #reads = 1078973 mem = 536880732 peak = 884527104
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (90, 283573, 34, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 303, 598)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1382)
[M::mem_pestat] mean and std.dev: (343.20, 226.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1774)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 266, 387)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 813)
[M::mem_pestat] mean and std.dev: (291.20, 146.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1026)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 510, 742)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1826)
[M::mem_pestat] mean and std.dev: (451.06, 326.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2368)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 407, 802)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1946)
[M::mem_pestat] mean and std.dev: (521.07, 441.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2518)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694954 sequences (100000075 bp) in 2.963 CPU sec, 3.159 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 283811, 42, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 480, 727)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1781)
[M::mem_pestat] mean and std.dev: (392.11, 246.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2308)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 257, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 782)
[M::mem_pestat] mean and std.dev: (282.90, 142.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 986)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 314, 2116)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6078)
[M::mem_pestat] mean and std.dev: (1205.81, 1581.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8059)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 425, 819)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2061)
[M::mem_pestat] mean and std.dev: (476.31, 359.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2682)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693028 sequences (100000236 bp) in 1.500 CPU sec, 1.496 real sec...
[M::mem_process_seqs] Processed 693048 reads in 164.116 CPU sec, 5.206 real sec
sorting block 9, #reads = 1079639 mem = 536877510 peak = 884527104
[M::mem_process_seqs] Processed 694838 reads in 106.867 CPU sec, 3.384 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 284295, 46, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (307, 417, 861)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1969)
[M::mem_pestat] mean and std.dev: (534.58, 418.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2523)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 258, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 779)
[M::mem_pestat] mean and std.dev: (282.25, 141.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 982)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 959, 3102)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8892)
[M::mem_pestat] mean and std.dev: (1600.60, 1949.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11787)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 318, 694)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1652)
[M::mem_pestat] mean and std.dev: (397.00, 333.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2131)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 10, #reads = 1080257 mem = 536879684 peak = 884527104
[M::process] read 692950 sequences (100000038 bp) in 2.618 CPU sec, 2.801 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 283763, 18, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 408, 984)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2600)
[M::mem_pestat] mean and std.dev: (445.73, 457.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3408)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 265, 382)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 798)
[M::mem_pestat] mean and std.dev: (289.18, 144.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1006)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (507, 1788, 2093)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5265)
[M::mem_pestat] mean and std.dev: (1460.61, 1064.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6851)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 315, 1694)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4646)
[M::mem_pestat] mean and std.dev: (748.37, 781.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6122)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694954 reads in 163.169 CPU sec, 5.193 real sec
[M::process] read 695084 sequences (100000283 bp) in 1.975 CPU sec, 2.012 real sec...
[M::mem_process_seqs] Processed 693028 reads in 106.282 CPU sec, 3.347 real sec
sorting block 11, #reads = 1080332 mem = 536879322 peak = 884527104
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 283530, 36, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 304, 1058)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2822)
[M::mem_pestat] mean and std.dev: (570.60, 535.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3704)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 265, 381)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 795)
[M::mem_pestat] mean and std.dev: (288.80, 144.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1002)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 463, 1658)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4630)
[M::mem_pestat] mean and std.dev: (914.77, 1062.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6116)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 337, 541)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1127)
[M::mem_pestat] mean and std.dev: (340.43, 155.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1420)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695058 sequences (100000249 bp) in 2.522 CPU sec, 2.647 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 283973, 33, 92)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 520, 1329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3459)
[M::mem_pestat] mean and std.dev: (850.75, 803.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4524)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 256, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 775)
[M::mem_pestat] mean and std.dev: (280.95, 141.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 977)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (108, 860, 1853)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5343)
[M::mem_pestat] mean and std.dev: (1088.73, 1125.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7088)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 393, 1031)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2739)
[M::mem_pestat] mean and std.dev: (517.12, 461.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3593)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 692950 reads in 163.517 CPU sec, 5.194 real sec
[M::process] read 693328 sequences (100000035 bp) in 2.053 CPU sec, 2.065 real sec...
[M::mem_process_seqs] Processed 695084 reads in 115.223 CPU sec, 3.658 real sec
sorting block 12, #reads = 1079458 mem = 536877792 peak = 884527104
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 284160, 24, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 296, 968)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2538)
[M::mem_pestat] mean and std.dev: (571.11, 593.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3323)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 256, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 772)
[M::mem_pestat] mean and std.dev: (280.70, 141.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 973)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 482, 764)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1880)
[M::mem_pestat] mean and std.dev: (509.67, 362.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2438)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 378, 863)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2145)
[M::mem_pestat] mean and std.dev: (502.65, 453.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2786)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694784 sequences (100000184 bp) in 2.448 CPU sec, 2.620 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 284319, 38, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 316, 697)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1619)
[M::mem_pestat] mean and std.dev: (427.51, 312.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2080)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 263, 380)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 794)
[M::mem_pestat] mean and std.dev: (287.59, 143.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1001)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 310, 579)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1335)
[M::mem_pestat] mean and std.dev: (367.61, 265.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1713)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 419, 1118)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2922)
[M::mem_pestat] mean and std.dev: (672.94, 581.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3824)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694656 sequences (100000181 bp) in 1.630 CPU sec, 1.635 real sec...
[M::mem_process_seqs] Processed 695058 reads in 162.683 CPU sec, 5.174 real sec
[M::mem_process_seqs] Processed 693328 reads in 105.926 CPU sec, 3.357 real sec
sorting block 13, #reads = 1079346 mem = 536881939 peak = 884527104
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 284052, 29, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 388, 650)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1598)
[M::mem_pestat] mean and std.dev: (418.73, 280.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2072)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 258, 376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 788)
[M::mem_pestat] mean and std.dev: (284.57, 144.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 994)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (68, 478, 746)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2102)
[M::mem_pestat] mean and std.dev: (398.32, 403.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2780)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 281, 658)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1536)
[M::mem_pestat] mean and std.dev: (345.62, 285.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1975)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 692774 sequences (100000083 bp) in 2.814 CPU sec, 2.985 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 284133, 27, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 275, 1163)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3143)
[M::mem_pestat] mean and std.dev: (546.40, 603.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4133)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 260, 379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 795)
[M::mem_pestat] mean and std.dev: (286.14, 145.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1003)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (414, 687, 1373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3291)
[M::mem_pestat] mean and std.dev: (748.96, 514.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4250)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 329, 588)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1342)
[M::mem_pestat] mean and std.dev: (345.51, 189.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1719)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697098 sequences (100000021 bp) in 1.650 CPU sec, 1.657 real sec...
[M::mem_process_seqs] Processed 694784 reads in 180.219 CPU sec, 5.984 real sec
sorting block 14, #reads = 1079846 mem = 536878429 peak = 884527104
[M::mem_process_seqs] Processed 694656 reads in 114.715 CPU sec, 3.646 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 283303, 19, 81)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 346, 923)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2307)
[M::mem_pestat] mean and std.dev: (518.79, 402.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2999)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 268, 389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 817)
[M::mem_pestat] mean and std.dev: (293.38, 148.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1031)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (417, 435, 892)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1842)
[M::mem_pestat] mean and std.dev: (481.47, 316.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2317)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 405, 714)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1670)
[M::mem_pestat] mean and std.dev: (434.41, 288.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2148)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 15, #reads = 1079824 mem = 536881257 peak = 909242368
[M::process] read 695794 sequences (100000031 bp) in 2.921 CPU sec, 3.090 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 285110, 34, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 314, 509)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1095)
[M::mem_pestat] mean and std.dev: (363.80, 220.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1388)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 254, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 778)
[M::mem_pestat] mean and std.dev: (279.34, 142.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 982)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (465, 764, 1670)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4080)
[M::mem_pestat] mean and std.dev: (959.06, 856.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5285)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 488, 1326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3522)
[M::mem_pestat] mean and std.dev: (729.39, 721.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4620)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 692774 reads in 167.634 CPU sec, 5.405 real sec
[M::mem_process_seqs] Processed 697098 reads in 110.546 CPU sec, 3.486 real sec
[M::process] read 694684 sequences (100000056 bp) in 2.166 CPU sec, 2.207 real sec...
sorting block 16, #reads = 1079351 mem = 536878476 peak = 909242368
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 284784, 34, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 337, 1547)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4231)
[M::mem_pestat] mean and std.dev: (736.19, 885.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5573)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 259, 377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 793)
[M::mem_pestat] mean and std.dev: (284.01, 143.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1001)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 412, 1111)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2993)
[M::mem_pestat] mean and std.dev: (488.33, 518.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3934)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 279, 684)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1680)
[M::mem_pestat] mean and std.dev: (332.19, 250.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2178)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695754 sequences (100000002 bp) in 3.198 CPU sec, 3.367 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 284512, 38, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 370, 791)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1959)
[M::mem_pestat] mean and std.dev: (517.12, 507.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2548)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 266, 388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 820)
[M::mem_pestat] mean and std.dev: (290.98, 147.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1036)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (130, 362, 688)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1804)
[M::mem_pestat] mean and std.dev: (467.12, 477.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2378)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 408, 1233)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3259)
[M::mem_pestat] mean and std.dev: (702.04, 734.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4272)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695794 reads in 163.676 CPU sec, 5.211 real sec
[M::mem_process_seqs] Processed 694684 reads in 108.854 CPU sec, 3.434 real sec
[M::process] read 695084 sequences (100000091 bp) in 2.320 CPU sec, 2.432 real sec...
sorting block 17, #reads = 1081996 mem = 536882799 peak = 909242368
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 284630, 18, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 329, 396)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 838)
[M::mem_pestat] mean and std.dev: (285.84, 140.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1059)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 259, 378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 798)
[M::mem_pestat] mean and std.dev: (284.54, 145.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1008)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 831, 1155)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3039)
[M::mem_pestat] mean and std.dev: (636.50, 510.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3981)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 277, 791)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2005)
[M::mem_pestat] mean and std.dev: (410.80, 347.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2612)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695202 sequences (100000065 bp) in 2.600 CPU sec, 2.809 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (81, 284883, 22, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 362, 783)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2015)
[M::mem_pestat] mean and std.dev: (484.93, 453.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2631)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 262, 383)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 809)
[M::mem_pestat] mean and std.dev: (288.06, 147.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1022)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (518, 1193, 1760)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4244)
[M::mem_pestat] mean and std.dev: (1290.05, 1115.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5752)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 316, 585)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1347)
[M::mem_pestat] mean and std.dev: (376.73, 263.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1728)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695754 reads in 160.297 CPU sec, 5.121 real sec
sorting block 18, #reads = 1082183 mem = 536878170 peak = 909242368
[M::process] read 695756 sequences (100000064 bp) in 2.172 CPU sec, 2.308 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 285002, 51, 87)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 416, 873)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2277)
[M::mem_pestat] mean and std.dev: (634.30, 555.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2979)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 262, 381)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 803)
[M::mem_pestat] mean and std.dev: (286.63, 145.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1014)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (296, 533, 1159)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2885)
[M::mem_pestat] mean and std.dev: (624.77, 487.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3748)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 429, 608)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1326)
[M::mem_pestat] mean and std.dev: (407.63, 245.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1685)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695202 reads in 86.691 CPU sec, 2.740 real sec
[M::process] read 693608 sequences (100000238 bp) in 1.472 CPU sec, 1.479 real sec...
sorting block 19, #reads = 1082502 mem = 536879002 peak = 909242368
[M::mem_process_seqs] Processed 695084 reads in 228.120 CPU sec, 7.231 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 285015, 41, 106)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (268, 435, 1166)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2962)
[M::mem_pestat] mean and std.dev: (754.20, 703.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3860)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 259, 379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 799)
[M::mem_pestat] mean and std.dev: (285.44, 145.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1009)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (537, 816, 2066)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5124)
[M::mem_pestat] mean and std.dev: (1146.84, 1138.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6653)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 375, 892)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2230)
[M::mem_pestat] mean and std.dev: (589.00, 574.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2899)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695674 sequences (100000002 bp) in 2.594 CPU sec, 2.807 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 284513, 26, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 343, 822)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2050)
[M::mem_pestat] mean and std.dev: (496.48, 414.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2664)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 270, 391)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 825)
[M::mem_pestat] mean and std.dev: (294.06, 149.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1042)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (132, 437, 1162)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3222)
[M::mem_pestat] mean and std.dev: (656.04, 714.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4252)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 326, 737)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1833)
[M::mem_pestat] mean and std.dev: (446.62, 408.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2381)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695756 reads in 174.179 CPU sec, 5.527 real sec
[M::mem_process_seqs] Processed 693608 reads in 105.412 CPU sec, 3.333 real sec
sorting block 20, #reads = 1083151 mem = 536880429 peak = 909242368
[M::process] read 695498 sequences (100000082 bp) in 1.911 CPU sec, 2.020 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 284462, 49, 92)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 405, 933)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2341)
[M::mem_pestat] mean and std.dev: (537.68, 459.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3045)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 259, 378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 796)
[M::mem_pestat] mean and std.dev: (284.59, 144.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1005)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (432, 898, 1463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3525)
[M::mem_pestat] mean and std.dev: (849.16, 662.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4556)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 355, 1023)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2673)
[M::mem_pestat] mean and std.dev: (668.45, 687.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3498)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 21, #reads = 1081354 mem = 536878033 peak = 909242368
[M::process] read 695364 sequences (100000061 bp) in 2.232 CPU sec, 2.402 real sec...
[M::process] read 695196 sequences (100000205 bp) in 1.390 CPU sec, 1.386 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 284551, 25, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 362, 1334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3568)
[M::mem_pestat] mean and std.dev: (686.24, 627.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4685)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 260, 381)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 803)
[M::mem_pestat] mean and std.dev: (286.05, 145.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1014)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 576, 2154)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6036)
[M::mem_pestat] mean and std.dev: (1139.68, 1243.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7977)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 435, 1030)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2634)
[M::mem_pestat] mean and std.dev: (533.42, 411.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3436)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695674 reads in 163.280 CPU sec, 5.214 real sec
[M::mem_process_seqs] Processed 695498 reads in 107.270 CPU sec, 3.413 real sec
sorting block 22, #reads = 1082342 mem = 536881008 peak = 909242368
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 285140, 43, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 386, 933)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2325)
[M::mem_pestat] mean and std.dev: (447.79, 366.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3021)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 259, 378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 796)
[M::mem_pestat] mean and std.dev: (284.82, 144.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1005)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 791, 2350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6624)
[M::mem_pestat] mean and std.dev: (1321.56, 1552.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8761)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 281, 730)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1850)
[M::mem_pestat] mean and std.dev: (403.19, 368.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2410)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693580 sequences (100000117 bp) in 2.428 CPU sec, 2.644 real sec...
[M::process] read 692030 sequences (100000227 bp) in 1.383 CPU sec, 1.392 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 284448, 41, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 356, 1217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3221)
[M::mem_pestat] mean and std.dev: (644.85, 694.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4223)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 260, 379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 797)
[M::mem_pestat] mean and std.dev: (285.72, 145.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1006)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (670, 879, 2049)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4807)
[M::mem_pestat] mean and std.dev: (1134.29, 922.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6186)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (297, 425, 1431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3699)
[M::mem_pestat] mean and std.dev: (676.82, 706.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4833)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695364 reads in 168.738 CPU sec, 5.470 real sec
[M::mem_process_seqs] Processed 695196 reads in 108.070 CPU sec, 3.452 real sec
sorting block 23, #reads = 1082316 mem = 536879105 peak = 909242368
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 283484, 40, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 444, 784)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1962)
[M::mem_pestat] mean and std.dev: (470.51, 368.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2551)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 264, 383)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 801)
[M::mem_pestat] mean and std.dev: (289.06, 145.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1010)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 1221, 3419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9873)
[M::mem_pestat] mean and std.dev: (1867.88, 2050.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13100)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 416, 747)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1913)
[M::mem_pestat] mean and std.dev: (424.15, 342.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2496)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695314 sequences (100000059 bp) in 2.488 CPU sec, 2.675 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 283710, 37, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (276, 470, 607)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1269)
[M::mem_pestat] mean and std.dev: (420.96, 213.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1600)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 273, 394)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 826)
[M::mem_pestat] mean and std.dev: (296.71, 148.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1042)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (356, 965, 1404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3500)
[M::mem_pestat] mean and std.dev: (829.49, 649.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4548)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 310, 506)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1082)
[M::mem_pestat] mean and std.dev: (314.55, 164.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1370)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694698 sequences (100000091 bp) in 1.800 CPU sec, 1.801 real sec...
[M::mem_process_seqs] Processed 693580 reads in 162.805 CPU sec, 5.178 real sec
[M::mem_process_seqs] Processed 692030 reads in 106.927 CPU sec, 3.388 real sec
sorting block 24, #reads = 1080493 mem = 536879446 peak = 909242368
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 284565, 33, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 285, 639)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1555)
[M::mem_pestat] mean and std.dev: (384.85, 303.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2013)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 258, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 782)
[M::mem_pestat] mean and std.dev: (282.91, 143.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 986)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (351, 494, 1414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3540)
[M::mem_pestat] mean and std.dev: (854.62, 811.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4603)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 238, 545)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1247)
[M::mem_pestat] mean and std.dev: (319.42, 248.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1598)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695198 sequences (100000088 bp) in 2.402 CPU sec, 2.591 real sec...
[M::process] read 694906 sequences (100000077 bp) in 1.460 CPU sec, 1.461 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 284027, 24, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 251, 659)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1663)
[M::mem_pestat] mean and std.dev: (382.37, 352.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2165)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 260, 378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 792)
[M::mem_pestat] mean and std.dev: (285.73, 145.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 999)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (274, 427, 863)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2041)
[M::mem_pestat] mean and std.dev: (562.95, 479.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2630)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 339, 502)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1110)
[M::mem_pestat] mean and std.dev: (345.08, 213.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1414)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695314 reads in 171.548 CPU sec, 5.719 real sec
sorting block 25, #reads = 1080332 mem = 536879825 peak = 909242368
[M::mem_process_seqs] Processed 694698 reads in 108.137 CPU sec, 3.441 real sec
sorting block 26, #reads = 1080867 mem = 536876577 peak = 985157632
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 284881, 27, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 401, 1122)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2888)
[M::mem_pestat] mean and std.dev: (699.35, 648.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3771)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 256, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 784)
[M::mem_pestat] mean and std.dev: (282.44, 143.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 989)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (283, 1224, 1665)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4429)
[M::mem_pestat] mean and std.dev: (1201.36, 1004.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5811)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 465, 1337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3627)
[M::mem_pestat] mean and std.dev: (817.43, 894.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4772)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694516 sequences (100000123 bp) in 2.855 CPU sec, 3.037 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 284131, 40, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 304, 669)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1583)
[M::mem_pestat] mean and std.dev: (367.38, 257.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2040)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 258, 376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 788)
[M::mem_pestat] mean and std.dev: (283.68, 143.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 994)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (361, 590, 1589)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4045)
[M::mem_pestat] mean and std.dev: (812.97, 609.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5273)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 296, 1019)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2665)
[M::mem_pestat] mean and std.dev: (511.53, 515.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3488)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 692260 sequences (100000010 bp) in 1.450 CPU sec, 1.445 real sec...
[M::mem_process_seqs] Processed 695198 reads in 167.087 CPU sec, 5.316 real sec
[M::mem_process_seqs] Processed 694906 reads in 109.091 CPU sec, 3.463 real sec
sorting block 27, #reads = 1080197 mem = 536880373 peak = 985157632
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 284022, 28, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 319, 686)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1632)
[M::mem_pestat] mean and std.dev: (470.25, 380.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2105)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 258, 375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 785)
[M::mem_pestat] mean and std.dev: (283.46, 142.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 990)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 547, 1407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3851)
[M::mem_pestat] mean and std.dev: (880.36, 1012.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5073)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 339, 621)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1535)
[M::mem_pestat] mean and std.dev: (373.02, 292.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1992)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694980 sequences (100000170 bp) in 2.566 CPU sec, 2.710 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (98, 282988, 47, 85)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 269, 622)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1526)
[M::mem_pestat] mean and std.dev: (342.51, 263.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1978)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 269, 386)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 806)
[M::mem_pestat] mean and std.dev: (292.44, 146.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1016)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (419, 642, 1156)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2630)
[M::mem_pestat] mean and std.dev: (630.85, 445.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3367)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (272, 371, 864)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2048)
[M::mem_pestat] mean and std.dev: (557.28, 418.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2640)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695052 sequences (100000134 bp) in 1.692 CPU sec, 1.704 real sec...
[M::mem_process_seqs] Processed 694516 reads in 166.392 CPU sec, 5.308 real sec
[M::mem_process_seqs] Processed 692260 reads in 108.833 CPU sec, 3.462 real sec
sorting block 28, #reads = 1080826 mem = 536879989 peak = 985157632
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 284108, 29, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 370, 981)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2479)
[M::mem_pestat] mean and std.dev: (618.38, 606.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3228)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 256, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 776)
[M::mem_pestat] mean and std.dev: (281.55, 141.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 978)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (70, 601, 1865)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5455)
[M::mem_pestat] mean and std.dev: (961.75, 825.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7250)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 358, 803)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1933)
[M::mem_pestat] mean and std.dev: (438.95, 323.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2498)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695082 sequences (100000051 bp) in 2.901 CPU sec, 3.068 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 284762, 24, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 272, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1009)
[M::mem_pestat] mean and std.dev: (256.47, 147.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1292)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 258, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 782)
[M::mem_pestat] mean and std.dev: (283.13, 142.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 986)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (326, 862, 1213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2987)
[M::mem_pestat] mean and std.dev: (822.33, 535.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3874)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 310, 401)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 743)
[M::mem_pestat] mean and std.dev: (301.75, 116.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 914)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695410 sequences (100000224 bp) in 1.903 CPU sec, 1.905 real sec...
[M::mem_process_seqs] Processed 694980 reads in 176.014 CPU sec, 5.844 real sec
sorting block 29, #reads = 1079299 mem = 536880923 peak = 985157632
[M::mem_process_seqs] Processed 695052 reads in 112.399 CPU sec, 3.552 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 284138, 19, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 235, 427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 913)
[M::mem_pestat] mean and std.dev: (271.57, 156.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1156)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 257, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 778)
[M::mem_pestat] mean and std.dev: (282.05, 142.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 981)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (995, 1333, 3183)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7559)
[M::mem_pestat] mean and std.dev: (1500.76, 1144.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9747)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 444, 1194)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3072)
[M::mem_pestat] mean and std.dev: (798.46, 759.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4011)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 30, #reads = 1080723 mem = 536881967 peak = 985157632
[M::process] read 695532 sequences (100000271 bp) in 2.331 CPU sec, 2.498 real sec...
[M::process] read 695038 sequences (100000257 bp) in 1.469 CPU sec, 1.478 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 284633, 30, 94)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 407, 1549)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4273)
[M::mem_pestat] mean and std.dev: (785.03, 819.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5635)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 256, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 784)
[M::mem_pestat] mean and std.dev: (282.57, 143.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 989)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (255, 940, 1790)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4860)
[M::mem_pestat] mean and std.dev: (1091.30, 1173.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6395)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 305, 628)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1528)
[M::mem_pestat] mean and std.dev: (380.90, 299.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1978)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695082 reads in 166.346 CPU sec, 5.308 real sec
[M::mem_process_seqs] Processed 695410 reads in 107.581 CPU sec, 3.415 real sec
sorting block 31, #reads = 1079369 mem = 536878589 peak = 985157632
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (94, 284336, 25, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 304, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 905)
[M::mem_pestat] mean and std.dev: (306.78, 147.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1139)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 257, 376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 790)
[M::mem_pestat] mean and std.dev: (283.63, 144.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 997)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (428, 781, 1686)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4202)
[M::mem_pestat] mean and std.dev: (1073.44, 847.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5460)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (264, 373, 821)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1935)
[M::mem_pestat] mean and std.dev: (473.97, 351.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2492)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697586 sequences (100000008 bp) in 2.981 CPU sec, 3.155 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 283898, 51, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 541, 867)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2225)
[M::mem_pestat] mean and std.dev: (564.49, 510.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2904)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 258, 376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 788)
[M::mem_pestat] mean and std.dev: (284.06, 144.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 994)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 627, 1323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3481)
[M::mem_pestat] mean and std.dev: (734.61, 609.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4560)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 343, 635)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1437)
[M::mem_pestat] mean and std.dev: (395.95, 279.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1838)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695532 reads in 171.454 CPU sec, 5.458 real sec
[M::mem_process_seqs] Processed 695038 reads in 112.636 CPU sec, 3.555 real sec
[M::process] read 696908 sequences (100000054 bp) in 2.415 CPU sec, 2.475 real sec...
sorting block 32, #reads = 1079165 mem = 536881402 peak = 985157632
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 285723, 30, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 332, 908)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2326)
[M::mem_pestat] mean and std.dev: (510.84, 538.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3035)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 252, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 771)
[M::mem_pestat] mean and std.dev: (277.49, 140.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 973)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (318, 948, 1900)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5064)
[M::mem_pestat] mean and std.dev: (988.56, 873.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6646)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 403, 1110)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2900)
[M::mem_pestat] mean and std.dev: (516.64, 531.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3795)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696924 sequences (100000286 bp) in 3.294 CPU sec, 3.492 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 285182, 36, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 291, 660)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1532)
[M::mem_pestat] mean and std.dev: (372.77, 296.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1968)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 256, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 779)
[M::mem_pestat] mean and std.dev: (279.40, 140.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 983)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (254, 462, 502)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 998)
[M::mem_pestat] mean and std.dev: (373.91, 203.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1246)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 279, 1263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3377)
[M::mem_pestat] mean and std.dev: (627.82, 741.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4434)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697586 reads in 173.615 CPU sec, 5.535 real sec
[M::mem_process_seqs] Processed 696908 reads in 113.104 CPU sec, 3.571 real sec
sorting block 33, #reads = 1079654 mem = 536880317 peak = 985157632
[M::process] read 695992 sequences (100000142 bp) in 2.491 CPU sec, 2.609 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 284866, 38, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 327, 622)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1502)
[M::mem_pestat] mean and std.dev: (393.78, 275.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1942)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 255, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 776)
[M::mem_pestat] mean and std.dev: (279.36, 140.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 979)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (259, 1606, 1989)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5449)
[M::mem_pestat] mean and std.dev: (1249.08, 971.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7179)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (294, 382, 1555)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4077)
[M::mem_pestat] mean and std.dev: (789.28, 842.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5338)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 34, #reads = 1080451 mem = 536878365 peak = 985157632
[M::process] read 695408 sequences (100000174 bp) in 3.105 CPU sec, 3.300 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (83, 284726, 15, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (255, 367, 925)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2265)
[M::mem_pestat] mean and std.dev: (620.28, 575.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2935)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 258, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 778)
[M::mem_pestat] mean and std.dev: (281.30, 140.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 981)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (372, 711, 1516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3804)
[M::mem_pestat] mean and std.dev: (1070.79, 1047.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5262)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 397, 855)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2219)
[M::mem_pestat] mean and std.dev: (447.67, 312.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2901)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696924 reads in 175.418 CPU sec, 5.593 real sec
[M::mem_process_seqs] Processed 695992 reads in 115.472 CPU sec, 3.647 real sec
[M::process] read 693374 sequences (100000145 bp) in 2.076 CPU sec, 2.151 real sec...
sorting block 35, #reads = 1080186 mem = 536879023 peak = 985157632
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 284546, 34, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 330, 509)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1049)
[M::mem_pestat] mean and std.dev: (348.65, 227.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1319)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 261, 378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 794)
[M::mem_pestat] mean and std.dev: (284.95, 143.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1002)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (977, 1883, 3296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7934)
[M::mem_pestat] mean and std.dev: (1820.39, 1186.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10253)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 337, 1347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3621)
[M::mem_pestat] mean and std.dev: (791.69, 947.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4758)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694122 sequences (100000204 bp) in 2.759 CPU sec, 2.964 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 283959, 34, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 266, 637)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1525)
[M::mem_pestat] mean and std.dev: (332.68, 263.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1969)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 272, 394)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 832)
[M::mem_pestat] mean and std.dev: (295.44, 148.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1051)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (418, 1618, 4704)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13276)
[M::mem_pestat] mean and std.dev: (2002.03, 1763.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17562)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 356, 1055)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2661)
[M::mem_pestat] mean and std.dev: (504.02, 478.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3464)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696488 sequences (100000142 bp) in 1.770 CPU sec, 1.771 real sec...
[M::mem_process_seqs] Processed 695408 reads in 176.895 CPU sec, 5.638 real sec
[M::mem_process_seqs] Processed 693374 reads in 114.862 CPU sec, 3.634 real sec
sorting block 36, #reads = 1081185 mem = 536877605 peak = 985157632
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 284364, 40, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 450, 962)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2592)
[M::mem_pestat] mean and std.dev: (568.05, 491.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3407)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 266, 385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 809)
[M::mem_pestat] mean and std.dev: (289.61, 145.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1021)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (457, 675, 2042)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5212)
[M::mem_pestat] mean and std.dev: (1011.11, 1047.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6797)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 412, 797)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1891)
[M::mem_pestat] mean and std.dev: (439.53, 269.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2438)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696192 sequences (100000060 bp) in 2.943 CPU sec, 3.124 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 284993, 26, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 303, 994)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2598)
[M::mem_pestat] mean and std.dev: (587.68, 623.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3400)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 256, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 783)
[M::mem_pestat] mean and std.dev: (281.30, 142.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 988)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 973, 3583)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10329)
[M::mem_pestat] mean and std.dev: (1899.15, 2282.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13702)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 330, 830)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2042)
[M::mem_pestat] mean and std.dev: (352.49, 233.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2648)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695862 sequences (100000022 bp) in 1.570 CPU sec, 1.569 real sec...
[M::mem_process_seqs] Processed 694122 reads in 171.073 CPU sec, 5.452 real sec
sorting block 37, #reads = 1079556 mem = 536881818 peak = 985157632
[M::mem_process_seqs] Processed 696488 reads in 112.995 CPU sec, 3.588 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 285060, 29, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 265, 389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 767)
[M::mem_pestat] mean and std.dev: (252.35, 100.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 956)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 258, 376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 792)
[M::mem_pestat] mean and std.dev: (283.28, 143.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1000)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 525, 730)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1832)
[M::mem_pestat] mean and std.dev: (530.44, 435.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2383)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 317, 814)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2064)
[M::mem_pestat] mean and std.dev: (503.58, 500.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2689)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695350 sequences (100000160 bp) in 2.710 CPU sec, 2.886 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 284669, 43, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 374, 1167)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3139)
[M::mem_pestat] mean and std.dev: (737.34, 755.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4125)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 258, 376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 790)
[M::mem_pestat] mean and std.dev: (283.15, 143.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 997)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (394, 735, 3453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9571)
[M::mem_pestat] mean and std.dev: (2214.07, 2617.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12685)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 323, 484)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 992)
[M::mem_pestat] mean and std.dev: (301.40, 120.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1246)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696192 reads in 167.731 CPU sec, 5.329 real sec
[M::process] read 695788 sequences (100000233 bp) in 1.915 CPU sec, 1.917 real sec...
sorting block 38, #reads = 1082049 mem = 536879334 peak = 985157632
[M::mem_process_seqs] Processed 695862 reads in 108.665 CPU sec, 3.427 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 285051, 36, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 292, 735)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1849)
[M::mem_pestat] mean and std.dev: (536.60, 510.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2578)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 259, 376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 788)
[M::mem_pestat] mean and std.dev: (283.76, 142.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 994)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (72, 547, 1796)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5244)
[M::mem_pestat] mean and std.dev: (966.40, 1184.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6968)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 359, 1000)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2594)
[M::mem_pestat] mean and std.dev: (574.79, 511.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3391)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 39, #reads = 1082110 mem = 536877589 peak = 985157632
[M::process] read 694828 sequences (100000074 bp) in 2.894 CPU sec, 3.064 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 285090, 32, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 388, 801)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1995)
[M::mem_pestat] mean and std.dev: (455.79, 403.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2592)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 258, 378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 796)
[M::mem_pestat] mean and std.dev: (284.22, 144.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1005)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 889, 2142)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5944)
[M::mem_pestat] mean and std.dev: (1162.93, 1311.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7845)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (270, 386, 645)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1395)
[M::mem_pestat] mean and std.dev: (418.02, 299.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1770)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695350 reads in 169.524 CPU sec, 5.404 real sec
[M::process] read 691888 sequences (100000055 bp) in 2.112 CPU sec, 2.158 real sec...
[M::mem_process_seqs] Processed 695788 reads in 112.945 CPU sec, 3.560 real sec
sorting block 40, #reads = 1082456 mem = 536879010 peak = 985157632
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 284159, 26, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 424, 557)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1233)
[M::mem_pestat] mean and std.dev: (359.70, 205.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1571)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 261, 380)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 798)
[M::mem_pestat] mean and std.dev: (286.53, 145.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1007)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (124, 514, 1396)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3940)
[M::mem_pestat] mean and std.dev: (830.64, 873.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5212)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (296, 391, 800)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1808)
[M::mem_pestat] mean and std.dev: (506.09, 397.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2312)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694472 sequences (100000161 bp) in 2.725 CPU sec, 2.919 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 283467, 27, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 763, 1482)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4012)
[M::mem_pestat] mean and std.dev: (951.49, 967.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5277)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 272, 391)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 819)
[M::mem_pestat] mean and std.dev: (295.11, 146.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1033)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 598, 2068)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5772)
[M::mem_pestat] mean and std.dev: (947.88, 884.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7624)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 361, 653)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1541)
[M::mem_pestat] mean and std.dev: (421.43, 323.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1985)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694728 sequences (100000127 bp) in 1.590 CPU sec, 1.589 real sec...
[M::mem_process_seqs] Processed 694828 reads in 173.704 CPU sec, 5.541 real sec
[M::mem_process_seqs] Processed 691888 reads in 112.227 CPU sec, 3.557 real sec
sorting block 41, #reads = 1082075 mem = 536878243 peak = 985157632
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 284289, 32, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 296, 506)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1070)
[M::mem_pestat] mean and std.dev: (328.21, 176.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1352)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 262, 378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 792)
[M::mem_pestat] mean and std.dev: (285.91, 143.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 999)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (285, 503, 2087)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5691)
[M::mem_pestat] mean and std.dev: (1193.61, 1560.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7493)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 292, 510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1084)
[M::mem_pestat] mean and std.dev: (345.40, 198.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1371)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695102 sequences (100000261 bp) in 2.985 CPU sec, 3.171 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 283972, 24, 89)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 487, 957)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2469)
[M::mem_pestat] mean and std.dev: (582.47, 527.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3225)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 260, 377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 789)
[M::mem_pestat] mean and std.dev: (285.11, 144.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 995)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (282, 734, 2119)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5793)
[M::mem_pestat] mean and std.dev: (1144.29, 1036.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7630)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 396, 834)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2038)
[M::mem_pestat] mean and std.dev: (569.37, 480.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2640)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694926 sequences (100000069 bp) in 1.439 CPU sec, 1.439 real sec...
[M::mem_process_seqs] Processed 694472 reads in 168.883 CPU sec, 5.382 real sec
sorting block 42, #reads = 1079936 mem = 536880184 peak = 985157632
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 284000, 26, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 340, 984)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2670)
[M::mem_pestat] mean and std.dev: (462.32, 427.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3513)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 259, 376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 788)
[M::mem_pestat] mean and std.dev: (284.42, 144.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 994)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (405, 677, 960)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2070)
[M::mem_pestat] mean and std.dev: (678.61, 540.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2839)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (271, 502, 1097)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2749)
[M::mem_pestat] mean and std.dev: (664.06, 574.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3575)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694906 sequences (100000056 bp) in 1.973 CPU sec, 1.977 real sec...
[M::mem_process_seqs] Processed 695102 reads in 100.715 CPU sec, 3.229 real sec
sorting block 43, #reads = 1081411 mem = 536878197 peak = 985157632
[M::mem_process_seqs] Processed 694728 reads in 244.724 CPU sec, 7.829 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 284215, 18, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 408, 1069)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2849)
[M::mem_pestat] mean and std.dev: (568.55, 544.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3739)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 259, 377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 791)
[M::mem_pestat] mean and std.dev: (284.40, 144.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 998)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (328, 839, 1706)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4462)
[M::mem_pestat] mean and std.dev: (1003.00, 831.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5840)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 297, 1105)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2841)
[M::mem_pestat] mean and std.dev: (507.20, 432.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3709)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695020 sequences (100000247 bp) in 2.794 CPU sec, 3.194 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 283968, 31, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 342, 769)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1979)
[M::mem_pestat] mean and std.dev: (468.48, 463.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2584)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 258, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (281.82, 141.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 974)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (336, 846, 1614)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4170)
[M::mem_pestat] mean and std.dev: (828.00, 628.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5448)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 453, 832)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2070)
[M::mem_pestat] mean and std.dev: (519.82, 372.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2689)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694926 reads in 186.233 CPU sec, 5.939 real sec
[M::mem_process_seqs] Processed 694906 reads in 110.606 CPU sec, 3.511 real sec
sorting block 44, #reads = 1081115 mem = 536883161 peak = 985157632
[M::process] read 695320 sequences (100000118 bp) in 2.121 CPU sec, 2.251 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 284047, 30, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 393, 1064)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2804)
[M::mem_pestat] mean and std.dev: (671.78, 670.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3674)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 257, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 779)
[M::mem_pestat] mean and std.dev: (282.36, 142.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 982)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 598, 1085)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2809)
[M::mem_pestat] mean and std.dev: (630.07, 574.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3671)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (260, 384, 1037)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2591)
[M::mem_pestat] mean and std.dev: (645.44, 588.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3368)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 45, #reads = 1080293 mem = 536880182 peak = 985157632
[M::process] read 695146 sequences (100000139 bp) in 2.662 CPU sec, 2.863 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 284055, 17, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 391, 1231)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3323)
[M::mem_pestat] mean and std.dev: (640.60, 615.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4369)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 255, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 777)
[M::mem_pestat] mean and std.dev: (280.77, 141.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 980)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 624, 904)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2430)
[M::mem_pestat] mean and std.dev: (568.12, 461.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3193)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 305, 836)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2094)
[M::mem_pestat] mean and std.dev: (526.85, 459.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2723)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694900 sequences (100000163 bp) in 1.690 CPU sec, 1.685 real sec...
[M::mem_process_seqs] Processed 695020 reads in 172.675 CPU sec, 5.515 real sec
[M::mem_process_seqs] Processed 695320 reads in 115.303 CPU sec, 3.713 real sec
sorting block 46, #reads = 1080526 mem = 536880364 peak = 985157632
[M::process] read 695284 sequences (100000003 bp) in 2.992 CPU sec, 3.337 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 284261, 30, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 354, 945)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2469)
[M::mem_pestat] mean and std.dev: (617.97, 650.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3231)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 256, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 778)
[M::mem_pestat] mean and std.dev: (281.95, 142.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 981)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (84, 650, 1456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4200)
[M::mem_pestat] mean and std.dev: (731.74, 850.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5572)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 302, 953)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2483)
[M::mem_pestat] mean and std.dev: (562.63, 566.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3248)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694900 reads in 103.433 CPU sec, 3.327 real sec
[M::process] read 695210 sequences (100000137 bp) in 2.067 CPU sec, 2.158 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 284516, 24, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 237, 503)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1153)
[M::mem_pestat] mean and std.dev: (266.94, 175.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1478)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 256, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 778)
[M::mem_pestat] mean and std.dev: (281.91, 142.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 981)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (372, 527, 1272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3072)
[M::mem_pestat] mean and std.dev: (538.10, 394.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3972)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 364, 856)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2122)
[M::mem_pestat] mean and std.dev: (543.17, 543.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2755)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 284482, 54, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 292, 707)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1749)
[M::mem_pestat] mean and std.dev: (420.44, 334.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2270)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 257, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 781)
[M::mem_pestat] mean and std.dev: (282.55, 143.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 985)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 758, 1668)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4462)
[M::mem_pestat] mean and std.dev: (969.56, 901.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5859)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 340, 556)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1272)
[M::mem_pestat] mean and std.dev: (328.79, 212.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1630)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695146 reads in 277.772 CPU sec, 8.997 real sec
sorting block 47, #reads = 1081060 mem = 536879967 peak = 985157632
[M::mem_process_seqs] Processed 695284 reads in 138.441 CPU sec, 4.512 real sec
[M::process] read 695420 sequences (100000162 bp) in 2.382 CPU sec, 2.513 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (98, 284699, 26, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (276, 453, 750)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1698)
[M::mem_pestat] mean and std.dev: (474.44, 300.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2172)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 257, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 784)
[M::mem_pestat] mean and std.dev: (283.06, 143.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 989)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (347, 474, 1597)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4097)
[M::mem_pestat] mean and std.dev: (904.64, 967.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5347)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 343, 2335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6595)
[M::mem_pestat] mean and std.dev: (1076.91, 1593.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8725)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 48, #reads = 1080792 mem = 536879404 peak = 1065750528
[M::process] read 695756 sequences (100000030 bp) in 2.997 CPU sec, 3.516 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 284164, 21, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 373, 780)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1884)
[M::mem_pestat] mean and std.dev: (421.66, 266.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2436)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 255, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 778)
[M::mem_pestat] mean and std.dev: (281.62, 143.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 981)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (334, 638, 1600)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4132)
[M::mem_pestat] mean and std.dev: (868.05, 896.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5398)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 339, 784)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1882)
[M::mem_pestat] mean and std.dev: (376.21, 259.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2431)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695210 reads in 184.239 CPU sec, 6.012 real sec
[M::mem_process_seqs] Processed 695420 reads in 124.251 CPU sec, 4.020 real sec
[M::process] read 693548 sequences (100000150 bp) in 2.389 CPU sec, 2.749 real sec...
sorting block 49, #reads = 1080346 mem = 536880155 peak = 1065750528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 284534, 49, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 304, 1645)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4543)
[M::mem_pestat] mean and std.dev: (853.83, 1075.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5992)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 257, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 781)
[M::mem_pestat] mean and std.dev: (281.85, 142.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 985)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (267, 1083, 1944)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5298)
[M::mem_pestat] mean and std.dev: (1062.80, 812.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6975)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (316, 460, 858)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1942)
[M::mem_pestat] mean and std.dev: (543.15, 360.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2484)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693478 sequences (100000059 bp) in 2.465 CPU sec, 2.882 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (81, 283487, 27, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 305, 678)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1678)
[M::mem_pestat] mean and std.dev: (364.36, 291.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2178)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 265, 378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 786)
[M::mem_pestat] mean and std.dev: (286.66, 141.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 990)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (434, 1459, 6815)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 19577)
[M::mem_pestat] mean and std.dev: (2813.19, 2667.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 25958)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 323, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 883)
[M::mem_pestat] mean and std.dev: (320.96, 140.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1093)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695756 reads in 184.217 CPU sec, 5.952 real sec
[M::mem_process_seqs] Processed 693548 reads in 120.284 CPU sec, 3.891 real sec
[M::process] read 693248 sequences (100000196 bp) in 2.113 CPU sec, 2.306 real sec...
sorting block 50, #reads = 1079407 mem = 536878636 peak = 1065750528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 283611, 35, 88)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 379, 680)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1678)
[M::mem_pestat] mean and std.dev: (379.38, 255.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2177)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 267, 382)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 798)
[M::mem_pestat] mean and std.dev: (288.63, 142.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1006)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (100, 444, 968)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2704)
[M::mem_pestat] mean and std.dev: (519.85, 485.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3572)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 271, 516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1208)
[M::mem_pestat] mean and std.dev: (358.99, 281.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1554)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694098 sequences (100000131 bp) in 2.796 CPU sec, 3.246 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 283810, 26, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 297, 1139)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3015)
[M::mem_pestat] mean and std.dev: (636.36, 787.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3953)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 266, 381)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 795)
[M::mem_pestat] mean and std.dev: (288.10, 142.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1002)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (399, 1184, 1364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3294)
[M::mem_pestat] mean and std.dev: (898.83, 529.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4259)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 270, 1324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3584)
[M::mem_pestat] mean and std.dev: (619.53, 696.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4714)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 693478 reads in 178.943 CPU sec, 5.786 real sec
sorting block 51, #reads = 1079953 mem = 536877656 peak = 1065750528
[M::mem_process_seqs] Processed 693248 reads in 119.930 CPU sec, 3.893 real sec
[M::process] read 694704 sequences (100000015 bp) in 2.057 CPU sec, 2.309 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 283888, 36, 91)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 328, 795)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2073)
[M::mem_pestat] mean and std.dev: (416.68, 291.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2712)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 263, 376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 784)
[M::mem_pestat] mean and std.dev: (284.81, 140.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 988)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (654, 2190, 2259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5469)
[M::mem_pestat] mean and std.dev: (1571.34, 1229.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7074)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 293, 875)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2255)
[M::mem_pestat] mean and std.dev: (430.02, 419.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2945)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 52, #reads = 1080799 mem = 536883030 peak = 1065750528
[M::process] read 691546 sequences (100000018 bp) in 2.853 CPU sec, 3.284 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 284585, 51, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 356, 847)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2061)
[M::mem_pestat] mean and std.dev: (531.97, 463.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2668)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 261, 377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 789)
[M::mem_pestat] mean and std.dev: (284.83, 142.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 995)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (410, 970, 1628)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4064)
[M::mem_pestat] mean and std.dev: (1158.33, 1015.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5282)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (297, 507, 1244)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3138)
[M::mem_pestat] mean and std.dev: (899.52, 885.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4440)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694098 reads in 178.754 CPU sec, 5.777 real sec
[M::mem_process_seqs] Processed 694704 reads in 120.791 CPU sec, 3.930 real sec
[M::process] read 694240 sequences (100000241 bp) in 2.039 CPU sec, 2.317 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 283425, 40, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 308, 558)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1296)
[M::mem_pestat] mean and std.dev: (382.08, 301.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1665)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 277, 397)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 831)
[M::mem_pestat] mean and std.dev: (299.07, 148.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1048)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (111, 518, 974)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2700)
[M::mem_pestat] mean and std.dev: (569.89, 535.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3563)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 346, 480)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 964)
[M::mem_pestat] mean and std.dev: (320.75, 141.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1206)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 53, #reads = 1081438 mem = 536879215 peak = 1065750528
[M::process] read 695944 sequences (100000279 bp) in 2.867 CPU sec, 3.254 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 284121, 46, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 264, 685)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1707)
[M::mem_pestat] mean and std.dev: (373.94, 242.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2218)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 265, 383)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 805)
[M::mem_pestat] mean and std.dev: (288.26, 144.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1016)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (476, 511, 2390)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6218)
[M::mem_pestat] mean and std.dev: (796.28, 858.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8132)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 402, 933)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2359)
[M::mem_pestat] mean and std.dev: (503.41, 404.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3072)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 691546 reads in 177.767 CPU sec, 5.787 real sec
[M::mem_process_seqs] Processed 694240 reads in 122.223 CPU sec, 4.056 real sec
[M::process] read 696682 sequences (100000124 bp) in 2.281 CPU sec, 2.800 real sec...
sorting block 54, #reads = 1081011 mem = 536878121 peak = 1065750528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 285257, 46, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 465, 1571)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4217)
[M::mem_pestat] mean and std.dev: (718.20, 663.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5540)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 259, 378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 798)
[M::mem_pestat] mean and std.dev: (284.26, 144.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1008)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (50, 403, 2884)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8552)
[M::mem_pestat] mean and std.dev: (1472.56, 2004.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11386)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 411, 1598)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4398)
[M::mem_pestat] mean and std.dev: (897.10, 900.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5798)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696644 sequences (100000031 bp) in 2.681 CPU sec, 3.169 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 285027, 29, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 294, 486)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1092)
[M::mem_pestat] mean and std.dev: (303.33, 153.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1395)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 255, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 782)
[M::mem_pestat] mean and std.dev: (280.44, 141.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 987)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 544, 3791)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10887)
[M::mem_pestat] mean and std.dev: (1957.34, 2115.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14435)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 416, 687)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1589)
[M::mem_pestat] mean and std.dev: (429.56, 329.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2040)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695944 reads in 185.206 CPU sec, 6.045 real sec
[M::mem_process_seqs] Processed 696682 reads in 124.083 CPU sec, 4.006 real sec
sorting block 55, #reads = 1080348 mem = 536880530 peak = 1065750528
[M::process] read 696850 sequences (100000006 bp) in 2.788 CPU sec, 3.125 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 285232, 41, 91)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 213, 399)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 857)
[M::mem_pestat] mean and std.dev: (274.52, 173.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1086)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 254, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (278.94, 140.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 975)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (354, 679, 1563)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3981)
[M::mem_pestat] mean and std.dev: (873.97, 786.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5190)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 435, 635)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1427)
[M::mem_pestat] mean and std.dev: (438.36, 294.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1823)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 56, #reads = 1081978 mem = 536882623 peak = 1065750528
[M::process] read 696394 sequences (100000242 bp) in 2.927 CPU sec, 3.199 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 285421, 27, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 369, 768)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1976)
[M::mem_pestat] mean and std.dev: (425.30, 364.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2580)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 255, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 785)
[M::mem_pestat] mean and std.dev: (280.81, 142.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 991)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (353, 480, 730)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1484)
[M::mem_pestat] mean and std.dev: (433.78, 283.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1861)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 342, 1495)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4003)
[M::mem_pestat] mean and std.dev: (780.52, 885.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5257)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696644 reads in 189.531 CPU sec, 6.153 real sec
[M::mem_process_seqs] Processed 696850 reads in 127.662 CPU sec, 4.127 real sec
[M::process] read 694944 sequences (100000058 bp) in 2.253 CPU sec, 2.388 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 284926, 40, 95)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 338, 1418)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3838)
[M::mem_pestat] mean and std.dev: (756.23, 838.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5048)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 256, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 783)
[M::mem_pestat] mean and std.dev: (281.67, 142.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 988)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (111, 573, 2117)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6129)
[M::mem_pestat] mean and std.dev: (1155.38, 1283.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8135)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 454, 970)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2404)
[M::mem_pestat] mean and std.dev: (598.77, 497.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3121)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 57, #reads = 1082933 mem = 536880780 peak = 1065750528
[M::process] read 693328 sequences (100000267 bp) in 3.043 CPU sec, 3.270 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 284033, 36, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 298, 550)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1260)
[M::mem_pestat] mean and std.dev: (324.09, 201.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1615)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 261, 379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 797)
[M::mem_pestat] mean and std.dev: (285.63, 143.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1006)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (441, 1222, 2053)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5277)
[M::mem_pestat] mean and std.dev: (1270.64, 934.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6889)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 355, 802)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1946)
[M::mem_pestat] mean and std.dev: (506.00, 452.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2518)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696394 reads in 190.032 CPU sec, 6.151 real sec
[M::mem_process_seqs] Processed 694944 reads in 128.072 CPU sec, 4.105 real sec
[M::process] read 695538 sequences (100000032 bp) in 2.453 CPU sec, 2.691 real sec...
sorting block 58, #reads = 1081464 mem = 536881619 peak = 1065750528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 283586, 41, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 369, 1409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3745)
[M::mem_pestat] mean and std.dev: (826.64, 908.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4913)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 269, 389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 817)
[M::mem_pestat] mean and std.dev: (293.23, 147.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1031)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 587, 1227)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3399)
[M::mem_pestat] mean and std.dev: (770.08, 793.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4485)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 505, 1591)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4271)
[M::mem_pestat] mean and std.dev: (948.04, 917.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5611)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695544 sequences (100000239 bp) in 2.894 CPU sec, 3.167 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 284810, 22, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 323, 1269)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3421)
[M::mem_pestat] mean and std.dev: (561.36, 600.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4497)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 258, 376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 790)
[M::mem_pestat] mean and std.dev: (283.40, 143.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 997)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (610, 1141, 1925)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4555)
[M::mem_pestat] mean and std.dev: (1188.41, 824.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5870)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (263, 463, 1216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3122)
[M::mem_pestat] mean and std.dev: (701.62, 707.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4075)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 693328 reads in 189.394 CPU sec, 6.099 real sec
[M::mem_process_seqs] Processed 695538 reads in 126.252 CPU sec, 4.035 real sec
[M::process] read 693886 sequences (100000189 bp) in 2.212 CPU sec, 2.293 real sec...
sorting block 59, #reads = 1080898 mem = 536877880 peak = 1065750528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 284431, 46, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 228, 499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1145)
[M::mem_pestat] mean and std.dev: (304.34, 193.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1468)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 258, 376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 790)
[M::mem_pestat] mean and std.dev: (283.81, 144.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 997)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 799, 2199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6199)
[M::mem_pestat] mean and std.dev: (1100.23, 1184.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8199)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 349, 1027)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2649)
[M::mem_pestat] mean and std.dev: (541.65, 543.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3460)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694962 sequences (100000061 bp) in 3.218 CPU sec, 3.688 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 284149, 26, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 329, 973)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2559)
[M::mem_pestat] mean and std.dev: (603.82, 634.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3352)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 266, 387)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 815)
[M::mem_pestat] mean and std.dev: (291.12, 147.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1029)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (97, 467, 1386)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3964)
[M::mem_pestat] mean and std.dev: (543.73, 659.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5253)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 438, 907)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2243)
[M::mem_pestat] mean and std.dev: (552.54, 451.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2911)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695544 reads in 188.029 CPU sec, 6.074 real sec
sorting block 60, #reads = 1080464 mem = 536880111 peak = 1065750528
[M::mem_process_seqs] Processed 693886 reads in 123.011 CPU sec, 3.922 real sec
[M::process] read 695140 sequences (100000068 bp) in 2.287 CPU sec, 2.457 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 283700, 20, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 434, 899)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2369)
[M::mem_pestat] mean and std.dev: (531.81, 461.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3104)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 260, 378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 794)
[M::mem_pestat] mean and std.dev: (285.04, 143.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1002)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (517, 995, 1627)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3847)
[M::mem_pestat] mean and std.dev: (859.29, 577.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4957)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 322, 678)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1648)
[M::mem_pestat] mean and std.dev: (401.56, 316.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2133)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 61, #reads = 1080824 mem = 536883465 peak = 1065750528
[M::process] read 695700 sequences (100000280 bp) in 2.997 CPU sec, 3.210 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 284423, 29, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 358, 559)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1259)
[M::mem_pestat] mean and std.dev: (391.30, 233.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1609)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 258, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 782)
[M::mem_pestat] mean and std.dev: (283.26, 142.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 986)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (87, 510, 1262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3612)
[M::mem_pestat] mean and std.dev: (722.31, 740.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4787)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 276, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 949)
[M::mem_pestat] mean and std.dev: (326.48, 208.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1205)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694962 reads in 190.073 CPU sec, 6.087 real sec
[M::process] read 695614 sequences (100000023 bp) in 2.084 CPU sec, 2.174 real sec...
[M::mem_process_seqs] Processed 695140 reads in 127.218 CPU sec, 4.039 real sec
sorting block 62, #reads = 1080406 mem = 536880157 peak = 1065750528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 284255, 29, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 362, 963)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2565)
[M::mem_pestat] mean and std.dev: (567.24, 544.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3366)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 255, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 771)
[M::mem_pestat] mean and std.dev: (279.50, 140.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 972)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (476, 719, 1747)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4289)
[M::mem_pestat] mean and std.dev: (889.04, 661.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5560)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 433, 1995)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5535)
[M::mem_pestat] mean and std.dev: (939.85, 1097.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7305)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695824 sequences (100000059 bp) in 3.138 CPU sec, 3.382 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 284463, 42, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 355, 676)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1586)
[M::mem_pestat] mean and std.dev: (448.65, 348.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2041)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 255, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 772)
[M::mem_pestat] mean and std.dev: (280.30, 141.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 973)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (83, 704, 1169)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3341)
[M::mem_pestat] mean and std.dev: (665.82, 527.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4427)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 319, 536)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1146)
[M::mem_pestat] mean and std.dev: (362.04, 210.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1451)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695368 sequences (100000052 bp) in 1.698 CPU sec, 1.721 real sec...
[M::mem_process_seqs] Processed 695700 reads in 187.039 CPU sec, 5.981 real sec
[M::mem_process_seqs] Processed 695614 reads in 124.849 CPU sec, 3.967 real sec
sorting block 63, #reads = 1079860 mem = 536880472 peak = 1065750528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 284360, 31, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 368, 767)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1897)
[M::mem_pestat] mean and std.dev: (387.60, 308.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2462)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 254, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 771)
[M::mem_pestat] mean and std.dev: (279.74, 141.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 972)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (71, 174, 1476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4286)
[M::mem_pestat] mean and std.dev: (587.10, 760.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5691)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 384, 1226)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3196)
[M::mem_pestat] mean and std.dev: (613.86, 530.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4181)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695546 sequences (100000096 bp) in 2.899 CPU sec, 3.100 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 284313, 27, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (267, 449, 801)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1869)
[M::mem_pestat] mean and std.dev: (513.15, 394.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2403)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 256, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 775)
[M::mem_pestat] mean and std.dev: (281.00, 141.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 977)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (451, 970, 2648)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7042)
[M::mem_pestat] mean and std.dev: (1452.74, 1455.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9239)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 544, 1077)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2839)
[M::mem_pestat] mean and std.dev: (597.29, 543.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3720)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695330 sequences (100000065 bp) in 1.796 CPU sec, 1.833 real sec...
[M::mem_process_seqs] Processed 695824 reads in 187.407 CPU sec, 5.994 real sec
sorting block 64, #reads = 1080008 mem = 536878032 peak = 1065750528
[M::mem_process_seqs] Processed 695368 reads in 122.983 CPU sec, 3.919 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 284582, 28, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 359, 828)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2106)
[M::mem_pestat] mean and std.dev: (395.84, 294.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2745)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 255, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 783)
[M::mem_pestat] mean and std.dev: (281.82, 143.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 988)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (371, 720, 1366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3356)
[M::mem_pestat] mean and std.dev: (697.73, 503.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4351)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 294, 460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 966)
[M::mem_pestat] mean and std.dev: (271.77, 119.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1219)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 65, #reads = 1080357 mem = 536880630 peak = 1065750528
[M::process] read 697794 sequences (100000117 bp) in 2.921 CPU sec, 3.142 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 284741, 26, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 517, 1557)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4271)
[M::mem_pestat] mean and std.dev: (719.81, 709.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5628)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 255, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 775)
[M::mem_pestat] mean and std.dev: (281.01, 142.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 977)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 657, 1957)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5485)
[M::mem_pestat] mean and std.dev: (951.13, 1059.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7249)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 330, 1278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3356)
[M::mem_pestat] mean and std.dev: (736.37, 819.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4395)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695546 reads in 178.564 CPU sec, 5.691 real sec
[M::process] read 700226 sequences (100000144 bp) in 2.006 CPU sec, 2.029 real sec...
[M::mem_process_seqs] Processed 695330 reads in 120.767 CPU sec, 3.806 real sec
sorting block 66, #reads = 1079134 mem = 536883238 peak = 1065750528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (81, 285203, 29, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 419, 1023)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2579)
[M::mem_pestat] mean and std.dev: (720.70, 699.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3520)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 247, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (274.26, 140.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 956)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (115, 217, 2723)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7939)
[M::mem_pestat] mean and std.dev: (1099.72, 1363.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10547)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 316, 586)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1368)
[M::mem_pestat] mean and std.dev: (345.51, 210.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1759)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697982 sequences (100000275 bp) in 2.896 CPU sec, 3.096 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 286833, 34, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 254, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 972)
[M::mem_pestat] mean and std.dev: (296.19, 184.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1233)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 241, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 768)
[M::mem_pestat] mean and std.dev: (272.80, 144.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 971)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (369, 1467, 4090)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11532)
[M::mem_pestat] mean and std.dev: (2804.68, 3208.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 15637)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 309, 800)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2056)
[M::mem_pestat] mean and std.dev: (446.55, 386.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2684)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699324 sequences (100000207 bp) in 2.005 CPU sec, 2.011 real sec...
[M::mem_process_seqs] Processed 697794 reads in 195.879 CPU sec, 6.246 real sec
[M::mem_process_seqs] Processed 700226 reads in 130.907 CPU sec, 4.153 real sec
sorting block 67, #reads = 1080016 mem = 536881185 peak = 1065750528
[M::process] read 699596 sequences (100000175 bp) in 3.227 CPU sec, 3.435 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 286814, 26, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 497, 1343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3557)
[M::mem_pestat] mean and std.dev: (676.02, 701.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4664)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 244, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 776)
[M::mem_pestat] mean and std.dev: (275.43, 144.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 981)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 471, 1802)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5046)
[M::mem_pestat] mean and std.dev: (943.12, 941.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6668)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 427, 830)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2010)
[M::mem_pestat] mean and std.dev: (537.89, 444.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2600)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699826 sequences (100000227 bp) in 2.116 CPU sec, 2.127 real sec...
[M::mem_process_seqs] Processed 699324 reads in 109.893 CPU sec, 3.457 real sec
sorting block 68, #reads = 1079469 mem = 536879428 peak = 1065750528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (81, 285435, 23, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (267, 414, 1317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3417)
[M::mem_pestat] mean and std.dev: (856.01, 881.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4467)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 251, 377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 801)
[M::mem_pestat] mean and std.dev: (282.39, 148.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1013)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (919, 1594, 2307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5083)
[M::mem_pestat] mean and std.dev: (1355.80, 775.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6471)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 338, 484)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1044)
[M::mem_pestat] mean and std.dev: (323.55, 199.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1324)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 286566, 14, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (272, 397, 653)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1415)
[M::mem_pestat] mean and std.dev: (411.50, 236.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1796)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 244, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 767)
[M::mem_pestat] mean and std.dev: (273.47, 142.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 969)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (369, 369, 898)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1956)
[M::mem_pestat] mean and std.dev: (573.57, 496.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2558)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 281, 645)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1541)
[M::mem_pestat] mean and std.dev: (330.69, 196.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1989)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697982 reads in 301.258 CPU sec, 9.571 real sec
[M::process] read 697794 sequences (100000295 bp) in 2.666 CPU sec, 2.692 real sec...
[M::mem_process_seqs] Processed 699596 reads in 149.550 CPU sec, 4.742 real sec
sorting block 69, #reads = 1080018 mem = 536880515 peak = 1065750528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 286035, 18, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 326, 951)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2565)
[M::mem_pestat] mean and std.dev: (474.58, 497.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3372)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 242, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (271.24, 140.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 952)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 743, 1087)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2885)
[M::mem_pestat] mean and std.dev: (603.53, 627.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3784)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 311, 1056)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2766)
[M::mem_pestat] mean and std.dev: (578.58, 602.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3621)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696710 sequences (100000237 bp) in 3.297 CPU sec, 3.571 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 286242, 29, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 296, 570)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1304)
[M::mem_pestat] mean and std.dev: (320.33, 213.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1671)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 251, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 791)
[M::mem_pestat] mean and std.dev: (280.46, 146.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1000)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 742, 1611)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4527)
[M::mem_pestat] mean and std.dev: (797.46, 646.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5985)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 420, 1563)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4243)
[M::mem_pestat] mean and std.dev: (872.68, 869.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5583)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699826 reads in 191.810 CPU sec, 6.133 real sec
[M::mem_process_seqs] Processed 697794 reads in 127.990 CPU sec, 4.045 real sec
[M::process] read 699746 sequences (100000258 bp) in 2.454 CPU sec, 2.526 real sec...
sorting block 70, #reads = 1082095 mem = 536878837 peak = 1065750528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 285616, 19, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 410, 583)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1367)
[M::mem_pestat] mean and std.dev: (386.23, 280.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1759)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 256, 378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 800)
[M::mem_pestat] mean and std.dev: (284.26, 147.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1011)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (270, 753, 1720)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4620)
[M::mem_pestat] mean and std.dev: (1117.53, 1059.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6070)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 343, 516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1148)
[M::mem_pestat] mean and std.dev: (358.91, 194.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1464)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700224 sequences (100000151 bp) in 2.884 CPU sec, 3.084 real sec...
sorting block 71, #reads = 1081650 mem = 536881286 peak = 1065750528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 286328, 26, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 291, 668)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1634)
[M::mem_pestat] mean and std.dev: (383.04, 310.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2117)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 242, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (271.63, 141.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 960)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (393, 1328, 2064)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5406)
[M::mem_pestat] mean and std.dev: (1059.04, 740.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7077)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (264, 366, 628)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1356)
[M::mem_pestat] mean and std.dev: (416.16, 258.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1720)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696710 reads in 195.658 CPU sec, 6.241 real sec
[M::process] read 699178 sequences (100000205 bp) in 2.130 CPU sec, 2.189 real sec...
[M::mem_process_seqs] Processed 699746 reads in 130.987 CPU sec, 4.153 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 286584, 20, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 367, 1234)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3338)
[M::mem_pestat] mean and std.dev: (595.34, 580.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4390)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 241, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (269.88, 139.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 952)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (476, 906, 1653)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4007)
[M::mem_pestat] mean and std.dev: (991.70, 746.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5184)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 451, 1102)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2872)
[M::mem_pestat] mean and std.dev: (645.18, 673.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3757)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 72, #reads = 1079317 mem = 536881876 peak = 1065750528
[M::process] read 697102 sequences (100000138 bp) in 3.050 CPU sec, 3.328 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 285911, 41, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 301, 1145)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3029)
[M::mem_pestat] mean and std.dev: (603.22, 647.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3971)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 245, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 776)
[M::mem_pestat] mean and std.dev: (275.33, 143.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 981)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (640, 901, 1532)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3316)
[M::mem_pestat] mean and std.dev: (1091.97, 785.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4234)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (293, 498, 947)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2255)
[M::mem_pestat] mean and std.dev: (619.20, 545.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2909)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700224 reads in 198.503 CPU sec, 6.347 real sec
[M::process] read 695352 sequences (100000012 bp) in 2.124 CPU sec, 2.142 real sec...
[M::mem_process_seqs] Processed 699178 reads in 132.148 CPU sec, 4.185 real sec
sorting block 73, #reads = 1079734 mem = 536878574 peak = 1065750528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 284922, 23, 93)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 258, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 986)
[M::mem_pestat] mean and std.dev: (309.79, 178.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1243)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 253, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 790)
[M::mem_pestat] mean and std.dev: (281.62, 145.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 998)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (305, 1110, 2168)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5894)
[M::mem_pestat] mean and std.dev: (1303.26, 1313.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7757)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 338, 898)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2274)
[M::mem_pestat] mean and std.dev: (484.80, 486.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2962)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698408 sequences (100000214 bp) in 3.018 CPU sec, 3.247 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 284471, 22, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (246, 528, 1211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3141)
[M::mem_pestat] mean and std.dev: (639.25, 500.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4106)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 259, 383)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 811)
[M::mem_pestat] mean and std.dev: (287.76, 148.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1025)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (73, 415, 1189)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3421)
[M::mem_pestat] mean and std.dev: (742.27, 892.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4537)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 523, 1214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3190)
[M::mem_pestat] mean and std.dev: (777.10, 790.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4178)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695270 sequences (100000239 bp) in 1.956 CPU sec, 1.963 real sec...
[M::mem_process_seqs] Processed 697102 reads in 195.724 CPU sec, 6.256 real sec
[M::mem_process_seqs] Processed 695352 reads in 130.079 CPU sec, 4.122 real sec
sorting block 74, #reads = 1079336 mem = 536878427 peak = 1065750528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 285494, 28, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 325, 664)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1516)
[M::mem_pestat] mean and std.dev: (391.94, 264.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1942)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 248, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 779)
[M::mem_pestat] mean and std.dev: (277.47, 143.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 984)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (130, 576, 1747)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4981)
[M::mem_pestat] mean and std.dev: (1074.96, 1174.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6598)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 470, 2022)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5564)
[M::mem_pestat] mean and std.dev: (1023.63, 1074.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7335)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696020 sequences (100000291 bp) in 2.942 CPU sec, 3.186 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 284617, 27, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 325, 807)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2051)
[M::mem_pestat] mean and std.dev: (368.25, 284.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2673)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 259, 381)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 805)
[M::mem_pestat] mean and std.dev: (286.43, 146.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1017)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 582, 3206)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9246)
[M::mem_pestat] mean and std.dev: (1572.30, 1864.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12266)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 403, 660)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1576)
[M::mem_pestat] mean and std.dev: (380.85, 261.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2034)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696012 sequences (100000036 bp) in 2.132 CPU sec, 2.140 real sec...
[M::mem_process_seqs] Processed 698408 reads in 201.667 CPU sec, 6.482 real sec
sorting block 75, #reads = 1076642 mem = 536877759 peak = 1065750528
[M::mem_process_seqs] Processed 695270 reads in 130.751 CPU sec, 4.143 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 284409, 33, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 442, 937)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2483)
[M::mem_pestat] mean and std.dev: (593.40, 547.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3256)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 253, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 779)
[M::mem_pestat] mean and std.dev: (280.28, 141.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 983)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (470, 1015, 2675)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7085)
[M::mem_pestat] mean and std.dev: (1415.83, 1367.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9290)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 315, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 885)
[M::mem_pestat] mean and std.dev: (339.30, 172.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1101)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 76, #reads = 1078743 mem = 536879393 peak = 1065750528
[M::process] read 694628 sequences (100000196 bp) in 3.035 CPU sec, 3.252 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 284143, 33, 90)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 315, 933)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2321)
[M::mem_pestat] mean and std.dev: (510.93, 484.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3015)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 254, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 783)
[M::mem_pestat] mean and std.dev: (281.31, 143.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 988)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (378, 782, 1224)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2916)
[M::mem_pestat] mean and std.dev: (675.43, 485.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3762)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 430, 1014)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2586)
[M::mem_pestat] mean and std.dev: (678.26, 659.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3372)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695412 sequences (100000244 bp) in 2.047 CPU sec, 2.051 real sec...
[M::mem_process_seqs] Processed 696020 reads in 196.717 CPU sec, 6.279 real sec
[M::mem_process_seqs] Processed 696012 reads in 131.040 CPU sec, 4.161 real sec
sorting block 77, #reads = 1076503 mem = 536883117 peak = 1065750528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (83, 284300, 24, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 783, 1310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3436)
[M::mem_pestat] mean and std.dev: (837.46, 727.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4499)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 261, 384)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 810)
[M::mem_pestat] mean and std.dev: (288.80, 147.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1023)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (611, 1425, 1991)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4751)
[M::mem_pestat] mean and std.dev: (1336.32, 875.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6131)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 326, 1019)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2677)
[M::mem_pestat] mean and std.dev: (535.85, 554.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3506)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696522 sequences (100000111 bp) in 3.133 CPU sec, 3.358 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 284425, 36, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 295, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1012)
[M::mem_pestat] mean and std.dev: (308.00, 171.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1287)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 256, 376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 790)
[M::mem_pestat] mean and std.dev: (284.04, 145.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 997)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (290, 988, 1364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3512)
[M::mem_pestat] mean and std.dev: (925.23, 572.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4586)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (306, 476, 929)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2175)
[M::mem_pestat] mean and std.dev: (682.84, 579.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3002)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694980 sequences (100000038 bp) in 1.941 CPU sec, 1.950 real sec...
[M::mem_process_seqs] Processed 694628 reads in 196.429 CPU sec, 6.264 real sec
[M::mem_process_seqs] Processed 695412 reads in 131.628 CPU sec, 4.178 real sec
sorting block 78, #reads = 1076109 mem = 536883377 peak = 1065750528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 284672, 43, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 264, 591)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1483)
[M::mem_pestat] mean and std.dev: (303.98, 212.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1929)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 251, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 772)
[M::mem_pestat] mean and std.dev: (278.28, 141.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 974)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (467, 1352, 2584)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6818)
[M::mem_pestat] mean and std.dev: (1503.33, 1532.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8935)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 272, 412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 792)
[M::mem_pestat] mean and std.dev: (271.20, 88.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 982)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695742 sequences (100000099 bp) in 3.037 CPU sec, 3.243 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 284215, 23, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 327, 1183)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3147)
[M::mem_pestat] mean and std.dev: (574.98, 612.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4129)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 258, 379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 799)
[M::mem_pestat] mean and std.dev: (285.76, 146.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1009)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (578, 875, 1990)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4814)
[M::mem_pestat] mean and std.dev: (978.95, 624.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6226)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 363, 704)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1600)
[M::mem_pestat] mean and std.dev: (428.23, 302.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2048)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696106 sequences (100000246 bp) in 2.149 CPU sec, 2.153 real sec...
[M::mem_process_seqs] Processed 696522 reads in 197.445 CPU sec, 6.286 real sec
sorting block 79, #reads = 1077391 mem = 536877308 peak = 1065750528
[M::mem_process_seqs] Processed 694980 reads in 130.707 CPU sec, 4.141 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 284058, 28, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 380, 1262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3368)
[M::mem_pestat] mean and std.dev: (751.10, 775.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4421)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 254, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 783)
[M::mem_pestat] mean and std.dev: (281.63, 143.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 988)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 571, 1200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3072)
[M::mem_pestat] mean and std.dev: (714.50, 636.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4008)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 552, 1089)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2885)
[M::mem_pestat] mean and std.dev: (692.48, 671.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3783)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 80, #reads = 1076580 mem = 536880895 peak = 1065750528
[M::process] read 695178 sequences (100000059 bp) in 2.933 CPU sec, 3.121 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 284558, 32, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 332, 545)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1291)
[M::mem_pestat] mean and std.dev: (382.98, 251.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1664)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 253, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 782)
[M::mem_pestat] mean and std.dev: (281.04, 144.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 987)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 500, 1886)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5242)
[M::mem_pestat] mean and std.dev: (1108.16, 1448.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6920)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (271, 498, 1182)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3004)
[M::mem_pestat] mean and std.dev: (670.51, 680.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3915)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702694 sequences (100000009 bp) in 2.174 CPU sec, 2.176 real sec...
[M::mem_process_seqs] Processed 695742 reads in 201.987 CPU sec, 6.642 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 283863, 43, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 332, 555)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1291)
[M::mem_pestat] mean and std.dev: (342.23, 209.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1659)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 257, 379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 799)
[M::mem_pestat] mean and std.dev: (285.30, 147.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1009)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (385, 524, 1290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3100)
[M::mem_pestat] mean and std.dev: (620.24, 515.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4005)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (258, 432, 981)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2427)
[M::mem_pestat] mean and std.dev: (646.06, 581.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3150)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703526 sequences (100000069 bp) in 2.249 CPU sec, 2.265 real sec...
[M::mem_process_seqs] Processed 695178 reads in 113.360 CPU sec, 3.596 real sec
sorting block 81, #reads = 1077723 mem = 536884473 peak = 1065750528
[M::mem_process_seqs] Processed 696106 reads in 296.850 CPU sec, 9.447 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 287584, 18, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 268, 760)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1964)
[M::mem_pestat] mean and std.dev: (396.94, 429.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2566)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 236, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 741)
[M::mem_pestat] mean and std.dev: (264.71, 137.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 936)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (63, 462, 720)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2034)
[M::mem_pestat] mean and std.dev: (299.67, 271.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2691)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 376, 907)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2217)
[M::mem_pestat] mean and std.dev: (478.72, 372.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2872)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 82, #reads = 1075968 mem = 536882201 peak = 1065750528
[M::process] read 701686 sequences (100000104 bp) in 2.851 CPU sec, 3.037 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 287742, 28, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 486, 946)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2374)
[M::mem_pestat] mean and std.dev: (612.44, 555.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3088)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 233, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 731)
[M::mem_pestat] mean and std.dev: (262.45, 136.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 923)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 751, 2702)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7682)
[M::mem_pestat] mean and std.dev: (1390.19, 1665.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10172)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 395, 1029)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2643)
[M::mem_pestat] mean and std.dev: (601.40, 614.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3450)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700868 sequences (100000123 bp) in 2.063 CPU sec, 2.071 real sec...
[M::mem_process_seqs] Processed 702694 reads in 249.004 CPU sec, 7.926 real sec
[M::mem_process_seqs] Processed 703526 reads in 154.682 CPU sec, 4.916 real sec
sorting block 83, #reads = 1075046 mem = 536880262 peak = 1065750528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 287495, 32, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 309, 747)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1843)
[M::mem_pestat] mean and std.dev: (393.70, 355.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2391)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 239, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 746)
[M::mem_pestat] mean and std.dev: (266.68, 136.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 942)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 1095, 2928)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8368)
[M::mem_pestat] mean and std.dev: (1944.59, 2280.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11088)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (265, 337, 1400)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3670)
[M::mem_pestat] mean and std.dev: (647.23, 669.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4805)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700828 sequences (100000274 bp) in 3.011 CPU sec, 3.256 real sec...
[M::process] read 699810 sequences (100000129 bp) in 2.118 CPU sec, 2.127 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 287148, 21, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 248, 741)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1863)
[M::mem_pestat] mean and std.dev: (472.31, 442.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2424)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 241, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (269.01, 138.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 955)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (293, 649, 2100)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5714)
[M::mem_pestat] mean and std.dev: (1173.05, 1419.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7521)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (288, 496, 1777)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4755)
[M::mem_pestat] mean and std.dev: (1038.91, 1032.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6244)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701686 reads in 223.255 CPU sec, 7.433 real sec
[M::mem_process_seqs] Processed 700868 reads in 143.754 CPU sec, 4.578 real sec
sorting block 84, #reads = 1073959 mem = 536882119 peak = 1065750528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 287238, 23, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 418, 1014)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2604)
[M::mem_pestat] mean and std.dev: (558.63, 482.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3399)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 242, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (268.48, 137.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 947)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 569, 1036)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2684)
[M::mem_pestat] mean and std.dev: (507.89, 567.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3508)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (259, 477, 1640)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4402)
[M::mem_pestat] mean and std.dev: (952.51, 1189.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5783)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698706 sequences (100000270 bp) in 2.802 CPU sec, 3.056 real sec...
[M::process] read 700112 sequences (100000150 bp) in 1.909 CPU sec, 1.916 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 286067, 39, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 293, 581)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1323)
[M::mem_pestat] mean and std.dev: (341.56, 228.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1694)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 244, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (271.48, 138.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 957)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 418, 1734)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4830)
[M::mem_pestat] mean and std.dev: (728.30, 785.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6378)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 288, 506)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1132)
[M::mem_pestat] mean and std.dev: (330.75, 200.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1445)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700828 reads in 211.988 CPU sec, 6.781 real sec
[M::mem_process_seqs] Processed 699810 reads in 142.511 CPU sec, 4.537 real sec
sorting block 85, #reads = 1075592 mem = 536878759 peak = 1065750528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 285955, 29, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 425, 1203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3129)
[M::mem_pestat] mean and std.dev: (615.18, 501.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4092)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 248, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 772)
[M::mem_pestat] mean and std.dev: (275.32, 141.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 975)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (282, 739, 1827)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4917)
[M::mem_pestat] mean and std.dev: (1031.96, 1105.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6462)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 304, 419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 879)
[M::mem_pestat] mean and std.dev: (298.34, 150.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1109)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 86, #reads = 1076171 mem = 536881731 peak = 1065750528
[M::process] read 700184 sequences (100000019 bp) in 3.040 CPU sec, 3.250 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 286961, 35, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 294, 906)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2316)
[M::mem_pestat] mean and std.dev: (556.07, 540.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3021)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 242, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (269.35, 137.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 948)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (742, 1207, 1939)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4333)
[M::mem_pestat] mean and std.dev: (1328.12, 1009.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5530)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 365, 737)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1733)
[M::mem_pestat] mean and std.dev: (436.38, 374.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2231)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699408 sequences (100000096 bp) in 2.088 CPU sec, 2.090 real sec...
[M::mem_process_seqs] Processed 698706 reads in 205.971 CPU sec, 6.573 real sec
[M::mem_process_seqs] Processed 700112 reads in 136.153 CPU sec, 4.322 real sec
sorting block 87, #reads = 1078252 mem = 536881846 peak = 1065750528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 286523, 44, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 350, 773)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1905)
[M::mem_pestat] mean and std.dev: (394.15, 280.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2471)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 240, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (268.77, 138.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 947)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (310, 755, 1594)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4162)
[M::mem_pestat] mean and std.dev: (982.31, 960.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5446)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 285, 658)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1544)
[M::mem_pestat] mean and std.dev: (350.77, 247.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1987)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696854 sequences (100000260 bp) in 2.885 CPU sec, 3.076 real sec...
[M::process] read 696814 sequences (100000088 bp) in 1.849 CPU sec, 1.859 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 286794, 40, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 289, 913)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2393)
[M::mem_pestat] mean and std.dev: (427.48, 402.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3133)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 245, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (272.69, 140.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 961)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (330, 758, 3742)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10566)
[M::mem_pestat] mean and std.dev: (2161.70, 2416.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13978)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 342, 602)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1468)
[M::mem_pestat] mean and std.dev: (366.97, 277.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1901)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700184 reads in 208.505 CPU sec, 6.657 real sec
[M::mem_process_seqs] Processed 699408 reads in 137.718 CPU sec, 4.389 real sec
sorting block 88, #reads = 1078185 mem = 536878874 peak = 1065750528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 285804, 18, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (277, 429, 1187)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3007)
[M::mem_pestat] mean and std.dev: (652.38, 548.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3917)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 254, 377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 799)
[M::mem_pestat] mean and std.dev: (282.08, 145.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1010)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1062, 4447, 4540)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11496)
[M::mem_pestat] mean and std.dev: (2914.50, 2312.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14974)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 525, 1099)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2819)
[M::mem_pestat] mean and std.dev: (580.68, 452.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3679)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697656 sequences (100000063 bp) in 3.405 CPU sec, 3.631 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (84, 285296, 23, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 334, 1622)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4436)
[M::mem_pestat] mean and std.dev: (908.37, 1002.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5843)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 255, 380)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 806)
[M::mem_pestat] mean and std.dev: (284.26, 147.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1019)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (362, 816, 1883)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4925)
[M::mem_pestat] mean and std.dev: (970.25, 723.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6446)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 379, 843)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2083)
[M::mem_pestat] mean and std.dev: (467.67, 410.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2703)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696848 sequences (100000228 bp) in 2.013 CPU sec, 2.023 real sec...
[M::mem_process_seqs] Processed 696854 reads in 199.064 CPU sec, 6.334 real sec
[M::mem_process_seqs] Processed 696814 reads in 133.357 CPU sec, 4.224 real sec
sorting block 89, #reads = 1078770 mem = 536879083 peak = 1065750528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 285579, 34, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 301, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 928)
[M::mem_pestat] mean and std.dev: (280.65, 115.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1168)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 250, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 780)
[M::mem_pestat] mean and std.dev: (278.59, 143.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 985)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (473, 734, 2241)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5777)
[M::mem_pestat] mean and std.dev: (1416.41, 1392.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7545)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 573, 788)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1874)
[M::mem_pestat] mean and std.dev: (616.27, 501.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2621)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696698 sequences (100000041 bp) in 2.930 CPU sec, 3.141 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 284902, 41, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 371, 1912)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5294)
[M::mem_pestat] mean and std.dev: (1056.67, 1270.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6985)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 252, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 790)
[M::mem_pestat] mean and std.dev: (281.05, 145.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 998)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 676, 970)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2554)
[M::mem_pestat] mean and std.dev: (598.81, 495.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3346)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (259, 547, 1620)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4342)
[M::mem_pestat] mean and std.dev: (956.58, 1110.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5703)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696124 sequences (100000257 bp) in 1.890 CPU sec, 1.901 real sec...
[M::mem_process_seqs] Processed 697656 reads in 205.491 CPU sec, 6.608 real sec
sorting block 90, #reads = 1077089 mem = 536878181 peak = 1065750528
[M::mem_process_seqs] Processed 696848 reads in 133.204 CPU sec, 4.237 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 285059, 32, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 340, 1439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3907)
[M::mem_pestat] mean and std.dev: (623.04, 680.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5141)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 253, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 788)
[M::mem_pestat] mean and std.dev: (281.95, 145.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 995)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 427, 942)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2516)
[M::mem_pestat] mean and std.dev: (659.13, 753.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3674)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 333, 702)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1688)
[M::mem_pestat] mean and std.dev: (460.01, 381.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2181)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 91, #reads = 1077835 mem = 536878315 peak = 1083678720
[M::process] read 693720 sequences (100000174 bp) in 3.018 CPU sec, 3.232 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 284540, 29, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 455, 1312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3534)
[M::mem_pestat] mean and std.dev: (740.86, 697.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4645)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 254, 375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 791)
[M::mem_pestat] mean and std.dev: (282.68, 145.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 999)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (278, 1033, 1822)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4910)
[M::mem_pestat] mean and std.dev: (1065.26, 1061.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6454)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 411, 865)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2199)
[M::mem_pestat] mean and std.dev: (519.09, 460.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2866)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696754 sequences (100000026 bp) in 1.981 CPU sec, 1.986 real sec...
[M::mem_process_seqs] Processed 696698 reads in 200.182 CPU sec, 6.401 real sec
[M::mem_process_seqs] Processed 696124 reads in 135.552 CPU sec, 4.311 real sec
sorting block 92, #reads = 1078054 mem = 536879851 peak = 1083678720
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 283997, 33, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 332, 810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2028)
[M::mem_pestat] mean and std.dev: (476.42, 459.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2637)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 265, 391)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 827)
[M::mem_pestat] mean and std.dev: (293.61, 150.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1045)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (313, 473, 826)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1852)
[M::mem_pestat] mean and std.dev: (459.04, 367.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2365)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 326, 856)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2112)
[M::mem_pestat] mean and std.dev: (432.86, 363.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2740)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696870 sequences (100000102 bp) in 2.881 CPU sec, 3.079 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 284872, 28, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 277, 908)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2420)
[M::mem_pestat] mean and std.dev: (487.05, 530.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3176)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 253, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 787)
[M::mem_pestat] mean and std.dev: (281.48, 145.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 994)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (372, 583, 1621)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4119)
[M::mem_pestat] mean and std.dev: (754.21, 843.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5368)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 335, 864)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2098)
[M::mem_pestat] mean and std.dev: (553.61, 503.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2715)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696236 sequences (100000139 bp) in 1.964 CPU sec, 1.970 real sec...
[M::mem_process_seqs] Processed 693720 reads in 193.384 CPU sec, 6.177 real sec
[M::mem_process_seqs] Processed 696754 reads in 129.550 CPU sec, 4.108 real sec
sorting block 93, #reads = 1076860 mem = 536879208 peak = 1083678720
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 285360, 22, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 455, 946)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2402)
[M::mem_pestat] mean and std.dev: (588.90, 522.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3130)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 251, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 784)
[M::mem_pestat] mean and std.dev: (280.05, 144.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 990)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 447, 1332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3686)
[M::mem_pestat] mean and std.dev: (761.10, 862.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4863)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 328, 714)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1724)
[M::mem_pestat] mean and std.dev: (447.60, 414.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2229)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697084 sequences (100000146 bp) in 2.822 CPU sec, 3.003 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 284853, 24, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 337, 499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1097)
[M::mem_pestat] mean and std.dev: (375.22, 247.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1396)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 254, 376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 794)
[M::mem_pestat] mean and std.dev: (283.47, 147.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1003)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (273, 765, 2215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6099)
[M::mem_pestat] mean and std.dev: (1242.23, 1459.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8041)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 409, 1069)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2713)
[M::mem_pestat] mean and std.dev: (628.02, 641.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3535)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696870 sequences (100000106 bp) in 1.798 CPU sec, 1.808 real sec...
[M::mem_process_seqs] Processed 696870 reads in 194.804 CPU sec, 6.214 real sec
sorting block 94, #reads = 1076134 mem = 536879315 peak = 1083678720
[M::mem_process_seqs] Processed 696236 reads in 129.343 CPU sec, 4.109 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 284887, 18, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (266, 498, 1330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3458)
[M::mem_pestat] mean and std.dev: (671.74, 571.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4522)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 250, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 783)
[M::mem_pestat] mean and std.dev: (280.01, 145.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 989)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (382, 543, 916)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1984)
[M::mem_pestat] mean and std.dev: (527.33, 323.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2518)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 382, 747)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1811)
[M::mem_pestat] mean and std.dev: (403.11, 303.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2343)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 95, #reads = 1078641 mem = 536878329 peak = 1083678720
[M::process] read 700148 sequences (100000235 bp) in 3.412 CPU sec, 3.571 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 284412, 20, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 335, 1270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3404)
[M::mem_pestat] mean and std.dev: (606.50, 608.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4471)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 251, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 787)
[M::mem_pestat] mean and std.dev: (280.90, 146.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 994)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (319, 959, 2118)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5716)
[M::mem_pestat] mean and std.dev: (966.78, 847.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7515)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 315, 799)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2047)
[M::mem_pestat] mean and std.dev: (465.56, 401.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2671)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699986 sequences (100000274 bp) in 1.978 CPU sec, 1.986 real sec...
[M::mem_process_seqs] Processed 697084 reads in 201.268 CPU sec, 6.400 real sec
[M::mem_process_seqs] Processed 696870 reads in 136.552 CPU sec, 4.330 real sec
sorting block 96, #reads = 1076697 mem = 536877148 peak = 1083678720
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 285708, 35, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 319, 717)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1773)
[M::mem_pestat] mean and std.dev: (402.39, 343.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2301)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 241, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (270.97, 140.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 956)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 816, 2882)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8166)
[M::mem_pestat] mean and std.dev: (1668.91, 1951.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10808)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 305, 674)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1682)
[M::mem_pestat] mean and std.dev: (368.15, 277.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2186)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699272 sequences (100000249 bp) in 2.787 CPU sec, 2.948 real sec...
[M::process] read 698338 sequences (100000280 bp) in 2.419 CPU sec, 2.421 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (103, 286295, 42, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 359, 1050)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2654)
[M::mem_pestat] mean and std.dev: (689.63, 628.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3456)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 245, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 767)
[M::mem_pestat] mean and std.dev: (273.10, 140.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 969)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 724, 1540)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4178)
[M::mem_pestat] mean and std.dev: (804.29, 712.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5497)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (269, 422, 1249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3209)
[M::mem_pestat] mean and std.dev: (745.91, 734.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4189)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700148 reads in 220.501 CPU sec, 7.044 real sec
[M::mem_process_seqs] Processed 699986 reads in 131.064 CPU sec, 4.154 real sec
sorting block 97, #reads = 1068937 mem = 536876328 peak = 1083678720
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 285988, 30, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 330, 636)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1576)
[M::mem_pestat] mean and std.dev: (414.82, 335.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2046)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 245, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 768)
[M::mem_pestat] mean and std.dev: (273.69, 140.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 970)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 583, 1069)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2763)
[M::mem_pestat] mean and std.dev: (787.07, 717.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3658)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (265, 467, 817)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1921)
[M::mem_pestat] mean and std.dev: (588.45, 445.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2473)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698370 sequences (100000206 bp) in 3.147 CPU sec, 3.309 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 286195, 22, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 296, 752)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1880)
[M::mem_pestat] mean and std.dev: (463.41, 461.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2444)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 248, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 770)
[M::mem_pestat] mean and std.dev: (275.55, 140.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 972)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 908, 1460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4108)
[M::mem_pestat] mean and std.dev: (967.95, 874.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5432)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 338, 556)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1322)
[M::mem_pestat] mean and std.dev: (377.66, 240.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1705)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699272 reads in 182.408 CPU sec, 5.803 real sec
[M::process] read 695854 sequences (100000260 bp) in 2.162 CPU sec, 2.189 real sec...
sorting block 98, #reads = 1080407 mem = 536878621 peak = 1083678720
[M::mem_process_seqs] Processed 698338 reads in 118.520 CPU sec, 3.735 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 286631, 31, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (132, 261, 551)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1389)
[M::mem_pestat] mean and std.dev: (292.83, 226.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1808)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 249, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 779)
[M::mem_pestat] mean and std.dev: (277.38, 142.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 984)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 641, 1963)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5475)
[M::mem_pestat] mean and std.dev: (841.36, 758.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7231)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 284, 393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 793)
[M::mem_pestat] mean and std.dev: (306.59, 143.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 993)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 99, #reads = 1082345 mem = 536877466 peak = 1083678720
[M::process] read 696024 sequences (100000278 bp) in 2.996 CPU sec, 3.143 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 285030, 35, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 283, 1001)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2625)
[M::mem_pestat] mean and std.dev: (347.27, 377.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3437)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 261, 383)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 809)
[M::mem_pestat] mean and std.dev: (286.97, 145.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1022)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (916, 1377, 2001)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4171)
[M::mem_pestat] mean and std.dev: (1649.29, 1027.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5758)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 267, 556)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1330)
[M::mem_pestat] mean and std.dev: (360.56, 295.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1717)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699054 sequences (100000232 bp) in 1.740 CPU sec, 1.741 real sec...
[M::mem_process_seqs] Processed 698370 reads in 174.148 CPU sec, 5.535 real sec
[M::mem_process_seqs] Processed 695854 reads in 113.869 CPU sec, 3.603 real sec
sorting block 100, #reads = 1082134 mem = 536878093 peak = 1083678720
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 285194, 47, 88)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 385, 557)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1337)
[M::mem_pestat] mean and std.dev: (333.62, 206.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1727)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 257, 379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 801)
[M::mem_pestat] mean and std.dev: (283.82, 144.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1012)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 427, 683)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1695)
[M::mem_pestat] mean and std.dev: (430.60, 358.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2201)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 456, 791)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1959)
[M::mem_pestat] mean and std.dev: (529.16, 437.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2543)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699722 sequences (100000245 bp) in 3.053 CPU sec, 3.219 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 286154, 32, 84)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 314, 887)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2355)
[M::mem_pestat] mean and std.dev: (448.91, 412.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3089)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 245, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 759)
[M::mem_pestat] mean and std.dev: (272.32, 138.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 958)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 437, 1376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3776)
[M::mem_pestat] mean and std.dev: (768.27, 927.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4976)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 350, 877)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2163)
[M::mem_pestat] mean and std.dev: (552.53, 444.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2806)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699548 sequences (100000124 bp) in 1.890 CPU sec, 1.891 real sec...
[M::mem_process_seqs] Processed 696024 reads in 176.349 CPU sec, 5.597 real sec
[M::mem_process_seqs] Processed 699054 reads in 117.014 CPU sec, 3.700 real sec
sorting block 101, #reads = 1078594 mem = 536877994 peak = 1083678720
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 286297, 15, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 321, 595)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1323)
[M::mem_pestat] mean and std.dev: (389.18, 240.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1687)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 243, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 749)
[M::mem_pestat] mean and std.dev: (269.70, 136.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 945)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1197, 2642, 4599)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11403)
[M::mem_pestat] mean and std.dev: (3397.07, 3039.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 15555)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (305, 407, 526)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 968)
[M::mem_pestat] mean and std.dev: (365.18, 152.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1189)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698330 sequences (100000146 bp) in 2.804 CPU sec, 2.962 real sec...
[M::process] read 698198 sequences (100000114 bp) in 1.563 CPU sec, 1.568 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 286893, 23, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 305, 534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1244)
[M::mem_pestat] mean and std.dev: (368.90, 271.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1599)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 245, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (270.81, 137.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 953)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (456, 845, 1092)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2364)
[M::mem_pestat] mean and std.dev: (787.23, 449.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3000)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (299, 984, 2181)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5945)
[M::mem_pestat] mean and std.dev: (1184.37, 1185.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7827)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699722 reads in 183.602 CPU sec, 5.849 real sec
sorting block 102, #reads = 1080331 mem = 536886669 peak = 1083678720
[M::mem_process_seqs] Processed 699548 reads in 119.272 CPU sec, 3.786 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 286031, 24, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 271, 512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1078)
[M::mem_pestat] mean and std.dev: (321.30, 173.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1361)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 249, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (274.99, 139.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 964)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (352, 501, 697)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1387)
[M::mem_pestat] mean and std.dev: (405.68, 175.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1732)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 375, 820)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2034)
[M::mem_pestat] mean and std.dev: (504.35, 434.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2641)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 103, #reads = 1080356 mem = 536884919 peak = 1083678720
[M::process] read 696818 sequences (100000196 bp) in 2.615 CPU sec, 2.748 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 285719, 36, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 333, 696)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1694)
[M::mem_pestat] mean and std.dev: (386.73, 303.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2193)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 249, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 770)
[M::mem_pestat] mean and std.dev: (275.85, 140.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 972)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (64, 566, 1189)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3439)
[M::mem_pestat] mean and std.dev: (658.20, 634.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4564)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (298, 357, 604)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1216)
[M::mem_pestat] mean and std.dev: (376.93, 150.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1522)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695832 sequences (100000183 bp) in 1.810 CPU sec, 1.807 real sec...
[M::mem_process_seqs] Processed 698330 reads in 176.202 CPU sec, 5.604 real sec
[M::mem_process_seqs] Processed 698198 reads in 114.821 CPU sec, 3.642 real sec
sorting block 104, #reads = 1080221 mem = 536879144 peak = 1083678720
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 284996, 21, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 492, 929)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2399)
[M::mem_pestat] mean and std.dev: (567.30, 451.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3134)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 253, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 787)
[M::mem_pestat] mean and std.dev: (280.54, 143.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 994)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (131, 812, 1383)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3887)
[M::mem_pestat] mean and std.dev: (900.90, 900.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5139)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 560, 739)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1743)
[M::mem_pestat] mean and std.dev: (560.77, 338.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2245)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698264 sequences (100000047 bp) in 2.831 CPU sec, 2.963 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (84, 284932, 37, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 337, 833)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2037)
[M::mem_pestat] mean and std.dev: (515.93, 432.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2639)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 258, 379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 801)
[M::mem_pestat] mean and std.dev: (285.01, 145.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1012)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (385, 456, 1078)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2464)
[M::mem_pestat] mean and std.dev: (615.52, 549.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3157)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 397, 884)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2160)
[M::mem_pestat] mean and std.dev: (540.02, 476.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2798)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696818 reads in 172.168 CPU sec, 5.468 real sec
[M::process] read 698100 sequences (100000228 bp) in 1.932 CPU sec, 1.934 real sec...
[M::mem_process_seqs] Processed 695832 reads in 112.421 CPU sec, 3.545 real sec
sorting block 105, #reads = 1079073 mem = 536878015 peak = 1083678720
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 285987, 27, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 362, 726)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1712)
[M::mem_pestat] mean and std.dev: (424.14, 357.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2205)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 249, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (275.31, 140.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 964)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 464, 1145)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3149)
[M::mem_pestat] mean and std.dev: (447.14, 481.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4151)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 299, 1152)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3154)
[M::mem_pestat] mean and std.dev: (586.18, 549.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4155)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697900 sequences (100000011 bp) in 2.549 CPU sec, 2.660 real sec...
[M::process] read 697570 sequences (100000011 bp) in 1.550 CPU sec, 1.550 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 285822, 25, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (252, 411, 1206)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3114)
[M::mem_pestat] mean and std.dev: (653.37, 638.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4068)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 249, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (276.27, 141.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 976)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 700, 932)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2424)
[M::mem_pestat] mean and std.dev: (621.29, 477.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3170)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 469, 1137)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2983)
[M::mem_pestat] mean and std.dev: (647.21, 559.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3906)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698264 reads in 173.909 CPU sec, 5.543 real sec
[M::mem_process_seqs] Processed 698100 reads in 114.270 CPU sec, 3.625 real sec
sorting block 106, #reads = 1080222 mem = 536878151 peak = 1083678720
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 285422, 43, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (252, 415, 564)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1188)
[M::mem_pestat] mean and std.dev: (347.39, 166.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1500)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 249, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 776)
[M::mem_pestat] mean and std.dev: (276.75, 141.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 980)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (297, 770, 1210)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3036)
[M::mem_pestat] mean and std.dev: (777.90, 627.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3949)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 402, 1008)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2544)
[M::mem_pestat] mean and std.dev: (633.73, 555.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3312)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697292 sequences (100000229 bp) in 2.896 CPU sec, 3.014 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 285524, 27, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 329, 1216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3286)
[M::mem_pestat] mean and std.dev: (529.79, 562.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4321)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 250, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 785)
[M::mem_pestat] mean and std.dev: (278.93, 143.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 992)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (430, 874, 1598)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3934)
[M::mem_pestat] mean and std.dev: (1077.26, 894.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5102)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 351, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 941)
[M::mem_pestat] mean and std.dev: (277.42, 126.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1196)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697788 sequences (100000193 bp) in 1.710 CPU sec, 1.712 real sec...
[M::mem_process_seqs] Processed 697900 reads in 180.672 CPU sec, 5.748 real sec
sorting block 107, #reads = 1081030 mem = 536878695 peak = 1083678720
[M::mem_process_seqs] Processed 697570 reads in 120.882 CPU sec, 3.826 real sec
sorting block 108, #reads = 1079581 mem = 536884767 peak = 1083678720
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 285649, 22, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 319, 1115)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2981)
[M::mem_pestat] mean and std.dev: (565.14, 555.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3914)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 250, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 777)
[M::mem_pestat] mean and std.dev: (278.09, 142.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 981)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (313, 603, 989)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2341)
[M::mem_pestat] mean and std.dev: (659.00, 407.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3017)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 454, 712)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1690)
[M::mem_pestat] mean and std.dev: (453.00, 308.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2179)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697892 sequences (100000252 bp) in 2.873 CPU sec, 3.008 real sec...
[M::process] read 697420 sequences (100000170 bp) in 1.630 CPU sec, 1.631 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 285509, 26, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 339, 1022)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2764)
[M::mem_pestat] mean and std.dev: (457.11, 396.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3635)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 249, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 782)
[M::mem_pestat] mean and std.dev: (278.80, 144.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 988)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 469, 833)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2189)
[M::mem_pestat] mean and std.dev: (529.42, 514.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2867)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 346, 497)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1139)
[M::mem_pestat] mean and std.dev: (363.18, 229.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1460)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697292 reads in 182.816 CPU sec, 5.819 real sec
[M::mem_process_seqs] Processed 697788 reads in 129.034 CPU sec, 4.128 real sec
sorting block 109, #reads = 1078785 mem = 536878938 peak = 1083678720
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 285435, 35, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 274, 385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 829)
[M::mem_pestat] mean and std.dev: (297.05, 192.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1065)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 248, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 776)
[M::mem_pestat] mean and std.dev: (277.53, 143.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 980)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (403, 730, 1993)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5173)
[M::mem_pestat] mean and std.dev: (1016.18, 996.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6763)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 273, 1147)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3059)
[M::mem_pestat] mean and std.dev: (516.02, 506.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4015)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698202 sequences (100000238 bp) in 2.626 CPU sec, 2.771 real sec...
[M::process] read 698704 sequences (100000149 bp) in 1.760 CPU sec, 1.766 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 284800, 28, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 329, 1178)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3092)
[M::mem_pestat] mean and std.dev: (602.29, 712.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4049)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 249, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 782)
[M::mem_pestat] mean and std.dev: (279.00, 144.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 988)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (521, 899, 1857)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4529)
[M::mem_pestat] mean and std.dev: (1195.96, 902.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5865)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (267, 398, 886)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2124)
[M::mem_pestat] mean and std.dev: (491.61, 344.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2743)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697892 reads in 186.100 CPU sec, 5.926 real sec
[M::mem_process_seqs] Processed 697420 reads in 122.800 CPU sec, 3.898 real sec
sorting block 110, #reads = 1076880 mem = 536882211 peak = 1083678720
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 285927, 25, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 337, 856)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2244)
[M::mem_pestat] mean and std.dev: (512.13, 547.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2938)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 246, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 766)
[M::mem_pestat] mean and std.dev: (274.68, 142.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 967)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 869, 1519)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4163)
[M::mem_pestat] mean and std.dev: (880.39, 870.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5485)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 351, 1322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3558)
[M::mem_pestat] mean and std.dev: (691.60, 711.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4676)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702618 sequences (100000038 bp) in 2.610 CPU sec, 2.726 real sec...
[M::process] read 703100 sequences (100000007 bp) in 1.550 CPU sec, 1.549 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 285216, 28, 92)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 413, 702)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1650)
[M::mem_pestat] mean and std.dev: (421.03, 303.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2124)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 243, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (272.26, 140.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (337, 1048, 3257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9097)
[M::mem_pestat] mean and std.dev: (1450.58, 1756.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12017)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 361, 671)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1511)
[M::mem_pestat] mean and std.dev: (453.20, 305.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1931)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698202 reads in 189.035 CPU sec, 6.027 real sec
sorting block 111, #reads = 1077391 mem = 536878697 peak = 1083678720
[M::mem_process_seqs] Processed 698704 reads in 126.041 CPU sec, 4.012 real sec
sorting block 112, #reads = 1075051 mem = 536879224 peak = 1083678720
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 287091, 23, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 342, 1264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3394)
[M::mem_pestat] mean and std.dev: (639.57, 702.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4459)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 235, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 735)
[M::mem_pestat] mean and std.dev: (264.12, 136.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 928)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (403, 1092, 2694)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7276)
[M::mem_pestat] mean and std.dev: (1457.57, 1266.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9567)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 311, 682)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1634)
[M::mem_pestat] mean and std.dev: (445.71, 386.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2110)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702636 sequences (100000123 bp) in 2.658 CPU sec, 2.789 real sec...
[M::process] read 703204 sequences (100000009 bp) in 1.910 CPU sec, 1.906 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 287404, 32, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (335, 554, 1166)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2828)
[M::mem_pestat] mean and std.dev: (726.40, 563.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3659)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 236, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (265.57, 137.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 952)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (122, 595, 1006)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2774)
[M::mem_pestat] mean and std.dev: (546.90, 443.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3658)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 258, 717)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1795)
[M::mem_pestat] mean and std.dev: (397.15, 292.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2334)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702618 reads in 205.451 CPU sec, 6.541 real sec
[M::mem_process_seqs] Processed 703100 reads in 134.503 CPU sec, 4.276 real sec
sorting block 113, #reads = 1071009 mem = 536876912 peak = 1083678720
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (83, 287542, 24, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 475, 846)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2106)
[M::mem_pestat] mean and std.dev: (527.24, 416.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2736)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 236, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 747)
[M::mem_pestat] mean and std.dev: (264.96, 136.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 944)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (306, 604, 987)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2349)
[M::mem_pestat] mean and std.dev: (652.78, 478.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3030)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 340, 700)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1612)
[M::mem_pestat] mean and std.dev: (413.72, 313.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2068)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699360 sequences (100000004 bp) in 3.119 CPU sec, 3.209 real sec...
[M::process] read 701742 sequences (100000106 bp) in 1.630 CPU sec, 1.635 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 287925, 26, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (277, 397, 1071)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2659)
[M::mem_pestat] mean and std.dev: (687.95, 598.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3453)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 233, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 728)
[M::mem_pestat] mean and std.dev: (260.80, 132.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 919)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (302, 977, 2174)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5918)
[M::mem_pestat] mean and std.dev: (1236.32, 1049.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7790)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 295, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1129)
[M::mem_pestat] mean and std.dev: (293.11, 175.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1458)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702636 reads in 196.369 CPU sec, 6.244 real sec
[M::mem_process_seqs] Processed 703204 reads in 127.325 CPU sec, 4.052 real sec
sorting block 114, #reads = 1073107 mem = 536879367 peak = 1083678720
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 285751, 43, 94)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 361, 965)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2509)
[M::mem_pestat] mean and std.dev: (435.04, 468.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3281)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 248, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 786)
[M::mem_pestat] mean and std.dev: (276.67, 142.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 994)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (320, 845, 1619)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4217)
[M::mem_pestat] mean and std.dev: (719.84, 547.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5516)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 394, 886)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2150)
[M::mem_pestat] mean and std.dev: (564.97, 515.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2782)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702288 sequences (100000205 bp) in 2.637 CPU sec, 2.750 real sec...
[M::process] read 703276 sequences (100000180 bp) in 2.060 CPU sec, 2.057 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 286987, 23, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 353, 726)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1830)
[M::mem_pestat] mean and std.dev: (396.64, 299.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2382)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 239, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (268.11, 138.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 651, 1550)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4214)
[M::mem_pestat] mean and std.dev: (1101.30, 1053.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5546)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 354, 988)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2532)
[M::mem_pestat] mean and std.dev: (596.31, 599.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3304)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699360 reads in 190.739 CPU sec, 6.062 real sec
sorting block 115, #reads = 1076677 mem = 536879454 peak = 1083678720
[M::mem_process_seqs] Processed 701742 reads in 125.065 CPU sec, 3.964 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 287468, 38, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 292, 1169)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3101)
[M::mem_pestat] mean and std.dev: (688.84, 830.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4067)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 236, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 744)
[M::mem_pestat] mean and std.dev: (265.40, 137.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 940)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (297, 655, 955)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2271)
[M::mem_pestat] mean and std.dev: (658.88, 531.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2929)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 502, 1617)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4501)
[M::mem_pestat] mean and std.dev: (709.75, 662.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5943)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 116, #reads = 1075376 mem = 536880135 peak = 1083678720
[M::process] read 701458 sequences (100000144 bp) in 3.208 CPU sec, 3.289 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 287446, 26, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 242, 689)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1695)
[M::mem_pestat] mean and std.dev: (420.33, 397.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2198)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 232, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 722)
[M::mem_pestat] mean and std.dev: (260.03, 132.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 911)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (345, 995, 1317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3261)
[M::mem_pestat] mean and std.dev: (772.13, 567.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4233)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 386, 1041)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2681)
[M::mem_pestat] mean and std.dev: (537.75, 504.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3501)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702288 reads in 186.150 CPU sec, 5.908 real sec
[M::process] read 700736 sequences (100000110 bp) in 2.175 CPU sec, 2.175 real sec...
[M::mem_process_seqs] Processed 703276 reads in 124.026 CPU sec, 3.910 real sec
sorting block 117, #reads = 1080471 mem = 536883345 peak = 1083678720
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 287036, 13, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 358, 620)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1478)
[M::mem_pestat] mean and std.dev: (427.77, 367.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1907)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 237, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 725)
[M::mem_pestat] mean and std.dev: (262.71, 132.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 914)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (330, 689, 911)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2073)
[M::mem_pestat] mean and std.dev: (603.15, 491.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2654)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 340, 1115)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2835)
[M::mem_pestat] mean and std.dev: (601.43, 555.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3695)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698522 sequences (100000033 bp) in 2.794 CPU sec, 2.894 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 286595, 32, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 434, 946)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2422)
[M::mem_pestat] mean and std.dev: (531.18, 443.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3160)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 240, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 741)
[M::mem_pestat] mean and std.dev: (266.41, 134.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 935)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 495, 959)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2433)
[M::mem_pestat] mean and std.dev: (506.52, 442.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3170)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 357, 521)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1151)
[M::mem_pestat] mean and std.dev: (331.62, 168.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1466)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698264 sequences (100000221 bp) in 2.040 CPU sec, 2.041 real sec...
[M::mem_process_seqs] Processed 701458 reads in 191.127 CPU sec, 6.078 real sec
[M::mem_process_seqs] Processed 700736 reads in 124.721 CPU sec, 3.951 real sec
sorting block 118, #reads = 1078008 mem = 536879248 peak = 1083678720
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 285910, 30, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 448, 769)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1833)
[M::mem_pestat] mean and std.dev: (501.54, 359.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2365)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 247, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (273.44, 138.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 963)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (355, 556, 1178)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2824)
[M::mem_pestat] mean and std.dev: (788.17, 666.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3647)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 371, 1283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3413)
[M::mem_pestat] mean and std.dev: (761.77, 713.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4478)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699742 sequences (100000292 bp) in 3.122 CPU sec, 3.210 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 285490, 38, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 263, 393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 801)
[M::mem_pestat] mean and std.dev: (262.83, 131.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1005)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 250, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 770)
[M::mem_pestat] mean and std.dev: (275.43, 139.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 972)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 611, 955)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2485)
[M::mem_pestat] mean and std.dev: (584.31, 432.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3250)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 396, 892)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2194)
[M::mem_pestat] mean and std.dev: (521.96, 469.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2845)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698522 reads in 176.863 CPU sec, 5.629 real sec
[M::mem_process_seqs] Processed 698264 reads in 112.258 CPU sec, 3.539 real sec
[M::process] read 699106 sequences (100000036 bp) in 2.186 CPU sec, 2.227 real sec...
sorting block 119, #reads = 1077579 mem = 536887885 peak = 1083678720
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 286126, 32, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 281, 391)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 829)
[M::mem_pestat] mean and std.dev: (288.44, 188.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1048)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 244, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 752)
[M::mem_pestat] mean and std.dev: (270.32, 137.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (443, 711, 1413)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3353)
[M::mem_pestat] mean and std.dev: (712.68, 415.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4323)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 319, 850)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2114)
[M::mem_pestat] mean and std.dev: (527.40, 427.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2746)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 120, #reads = 1076666 mem = 536881077 peak = 1083678720
[M::process] read 698558 sequences (100000007 bp) in 2.656 CPU sec, 2.800 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 285708, 31, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 325, 1237)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3411)
[M::mem_pestat] mean and std.dev: (695.31, 729.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4498)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 246, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (271.77, 137.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (473, 924, 1733)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4253)
[M::mem_pestat] mean and std.dev: (978.20, 765.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5513)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 379, 1241)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3383)
[M::mem_pestat] mean and std.dev: (500.64, 504.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4454)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699742 reads in 167.082 CPU sec, 5.315 real sec
[M::process] read 698362 sequences (100000139 bp) in 1.839 CPU sec, 1.835 real sec...
[M::mem_process_seqs] Processed 699106 reads in 106.041 CPU sec, 3.354 real sec
sorting block 121, #reads = 1078491 mem = 536879725 peak = 1083678720
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 285922, 42, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 289, 1059)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2787)
[M::mem_pestat] mean and std.dev: (577.31, 526.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3651)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 247, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (273.86, 138.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 963)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (410, 1033, 3654)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10142)
[M::mem_pestat] mean and std.dev: (2294.83, 2766.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13386)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 371, 1650)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4568)
[M::mem_pestat] mean and std.dev: (909.10, 1078.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6027)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698116 sequences (100000178 bp) in 2.806 CPU sec, 2.917 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 286049, 21, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 299, 1060)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2870)
[M::mem_pestat] mean and std.dev: (549.85, 634.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3775)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 247, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (273.23, 137.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 959)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (309, 646, 1435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3687)
[M::mem_pestat] mean and std.dev: (818.75, 591.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4813)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 600, 1686)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4582)
[M::mem_pestat] mean and std.dev: (928.80, 993.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6030)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698070 sequences (100000143 bp) in 1.890 CPU sec, 1.888 real sec...
[M::mem_process_seqs] Processed 698558 reads in 179.721 CPU sec, 5.713 real sec
[M::mem_process_seqs] Processed 698362 reads in 114.169 CPU sec, 3.610 real sec
sorting block 122, #reads = 1078125 mem = 536881527 peak = 1083678720
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 285663, 43, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 485, 830)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2036)
[M::mem_pestat] mean and std.dev: (495.74, 395.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2639)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 249, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 770)
[M::mem_pestat] mean and std.dev: (276.14, 141.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 972)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (383, 902, 1339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3251)
[M::mem_pestat] mean and std.dev: (757.50, 530.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4207)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (280, 394, 833)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1939)
[M::mem_pestat] mean and std.dev: (515.00, 402.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2492)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697906 sequences (100000246 bp) in 2.774 CPU sec, 2.912 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 285298, 30, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 226, 392)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 832)
[M::mem_pestat] mean and std.dev: (245.31, 141.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1052)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 248, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (274.59, 139.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 963)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (132, 231, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1050)
[M::mem_pestat] mean and std.dev: (197.88, 141.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1356)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 388, 873)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2187)
[M::mem_pestat] mean and std.dev: (467.39, 314.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2844)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698116 reads in 176.858 CPU sec, 5.618 real sec
[M::process] read 697530 sequences (100000238 bp) in 1.940 CPU sec, 1.939 real sec...
[M::mem_process_seqs] Processed 698070 reads in 117.928 CPU sec, 3.723 real sec
sorting block 123, #reads = 1079151 mem = 536886997 peak = 1083678720
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 285734, 31, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 300, 988)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2634)
[M::mem_pestat] mean and std.dev: (514.02, 513.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3457)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 249, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 770)
[M::mem_pestat] mean and std.dev: (275.95, 141.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 972)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (319, 877, 1539)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3979)
[M::mem_pestat] mean and std.dev: (946.90, 761.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5199)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 324, 1330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3516)
[M::mem_pestat] mean and std.dev: (581.73, 607.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4609)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697746 sequences (100000040 bp) in 2.536 CPU sec, 2.659 real sec...
[M::process] read 697106 sequences (100000083 bp) in 1.530 CPU sec, 1.530 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 285104, 33, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 332, 1127)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2981)
[M::mem_pestat] mean and std.dev: (501.80, 421.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3908)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 249, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 770)
[M::mem_pestat] mean and std.dev: (276.32, 141.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 972)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (333, 801, 1889)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5001)
[M::mem_pestat] mean and std.dev: (1294.03, 1258.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6557)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 411, 765)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1839)
[M::mem_pestat] mean and std.dev: (462.73, 333.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2376)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697906 reads in 177.852 CPU sec, 5.669 real sec
sorting block 124, #reads = 1077658 mem = 536882740 peak = 1083678720
[M::mem_process_seqs] Processed 697530 reads in 116.718 CPU sec, 3.710 real sec
sorting block 125, #reads = 1078860 mem = 536885933 peak = 1124118528
[M::process] read 366740 sequences (52454744 bp) in 1.760 CPU sec, 1.813 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 285011, 27, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 287, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 984)
[M::mem_pestat] mean and std.dev: (282.55, 183.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1251)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 248, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (276.88, 142.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 976)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (291, 605, 3293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9297)
[M::mem_pestat] mean and std.dev: (1503.41, 1801.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12299)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 267, 519)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1155)
[M::mem_pestat] mean and std.dev: (277.96, 177.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1473)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 284579, 31, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 351, 783)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2049)
[M::mem_pestat] mean and std.dev: (384.76, 309.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2682)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 250, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 774)
[M::mem_pestat] mean and std.dev: (278.14, 142.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 977)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (425, 972, 1978)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5084)
[M::mem_pestat] mean and std.dev: (1116.06, 830.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6637)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 427, 667)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1545)
[M::mem_pestat] mean and std.dev: (420.44, 246.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1984)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697746 reads in 174.699 CPU sec, 5.634 real sec
[M::mem_process_seqs] Processed 697106 reads in 112.704 CPU sec, 3.649 real sec
sorting block 126, #reads = 1078438 mem = 536882383 peak = 1124118528
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 150072, 11, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 284, 699)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1789)
[M::mem_pestat] mean and std.dev: (434.77, 460.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2334)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 242, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 749)
[M::mem_pestat] mean and std.dev: (270.09, 139.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 945)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 655, 1802)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4962)
[M::mem_pestat] mean and std.dev: (962.18, 827.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6542)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 349, 523)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1149)
[M::mem_pestat] mean and std.dev: (348.12, 182.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1462)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 366740 reads in 52.849 CPU sec, 1.773 real sec
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 136903518
overall: 70066946048 mem 21331.372 user 605.208 sys 730.014 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1136_6G2-T1-TDNA-1_A23MHWWLT4_1.L008\tPU:L008\tSM:1136_6G2-T1-TDNA-1_A23MHWWLT4_1\tLB:1136_6G2-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1136_6G2-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1136_6G2-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 730.087 sec; CPU: 21936.618 sec
sorting block 127, #reads = 1007500 mem = 501973383 peak = 1124118528
uniq header count 1
merging 128 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31 max 192
algo: util-sort
license: sentieon:util=1
output file size: 7629611950
output reads: 138093209
bam_mem_sort: 128 calls 79.197 user 2.026 sys 82.151 real
bam_write: 128 calls 45.173 user 2.743 sys 61.700 real
execute: 1 calls 36.076 user 1.377 sys 774.568 real
merge_files: 1 calls 36.061 user 1.348 sys 43.874 real
parse_chunk: 2047 calls 91.049 user 22.899 sys 120.192 real
read_chunk: 5533 calls 42.546 user 36.308 sys 653.252 real
sort_block: 1 calls 30.116 user 35.697 sys 633.865 real
write_chunk: 3484 calls 35.678 user 1.043 sys 42.855 real
overall: 3284045824 mem 1770.582 user 82.592 sys 774.590 real
ls: cannot access '*.cram': No such file or directory