cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1136_253-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 1981.620 CPU sec, 79.081 real sec
[M::process] read 687112 sequences (100000105 bp) in 0.993 CPU sec, 0.994 real sec...
[M::process] read 686642 sequences (100000197 bp) in 1.480 CPU sec, 1.483 real sec...
[M::process] read 686486 sequences (100000093 bp) in 1.553 CPU sec, 1.572 real sec...
[M::process] read 686262 sequences (100000086 bp) in 1.587 CPU sec, 1.601 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 279646, 4, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 277, 538)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1196)
[M::mem_pestat] mean and std.dev: (356.42, 214.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1525)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 299, 426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 892)
[M::mem_pestat] mean and std.dev: (320.85, 158.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1125)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 314, 1307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3457)
[M::mem_pestat] mean and std.dev: (587.27, 589.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4532)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 686642 reads in 105.621 CPU sec, 3.366 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 279856, 12, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 334, 754)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1984)
[M::mem_pestat] mean and std.dev: (421.61, 421.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2599)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 296, 422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 884)
[M::mem_pestat] mean and std.dev: (318.33, 158.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1115)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (646, 723, 1290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2578)
[M::mem_pestat] mean and std.dev: (852.17, 492.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3222)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (259, 336, 639)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1399)
[M::mem_pestat] mean and std.dev: (430.78, 293.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1779)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 685868 sequences (100000206 bp) in 1.429 CPU sec, 1.439 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 279430, 14, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 345, 513)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1067)
[M::mem_pestat] mean and std.dev: (344.74, 201.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1344)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 298, 424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 886)
[M::mem_pestat] mean and std.dev: (319.95, 157.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1117)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 973, 1781)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4987)
[M::mem_pestat] mean and std.dev: (955.38, 783.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6590)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 329, 596)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1392)
[M::mem_pestat] mean and std.dev: (384.09, 280.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1790)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 687112 reads in 291.578 CPU sec, 9.259 real sec
sorting block 0, #reads = 1071558 mem = 536881348 peak = 603377664
[M::mem_process_seqs] Processed 686486 reads in 147.982 CPU sec, 4.755 real sec
[M::process] read 685450 sequences (100000217 bp) in 1.860 CPU sec, 1.945 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 279400, 5, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 300, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 623)
[M::mem_pestat] mean and std.dev: (262.72, 98.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 761)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 300, 427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 893)
[M::mem_pestat] mean and std.dev: (321.31, 158.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1126)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 311, 630)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1552)
[M::mem_pestat] mean and std.dev: (352.35, 221.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2013)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 684810 sequences (100000043 bp) in 1.727 CPU sec, 1.728 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 279423, 18, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 300, 634)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1584)
[M::mem_pestat] mean and std.dev: (442.74, 415.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2105)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 301, 429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 897)
[M::mem_pestat] mean and std.dev: (323.05, 158.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1131)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 368, 504)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1242)
[M::mem_pestat] mean and std.dev: (306.71, 196.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1611)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 358, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 976)
[M::mem_pestat] mean and std.dev: (339.97, 191.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1237)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 686262 reads in 192.487 CPU sec, 6.125 real sec
sorting block 1, #reads = 1069839 mem = 536877078 peak = 784171008
[M::mem_process_seqs] Processed 685868 reads in 215.208 CPU sec, 6.869 real sec
sorting block 2, #reads = 1070086 mem = 536877497 peak = 878919680
[M::process] read 684416 sequences (100000278 bp) in 2.105 CPU sec, 2.204 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 278624, 12, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 267, 766)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1908)
[M::mem_pestat] mean and std.dev: (369.23, 364.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2479)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 305, 434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 908)
[M::mem_pestat] mean and std.dev: (326.65, 160.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1145)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (579, 747, 910)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1572)
[M::mem_pestat] mean and std.dev: (651.09, 259.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1903)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 339, 403)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 789)
[M::mem_pestat] mean and std.dev: (303.97, 134.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 982)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 684206 sequences (100000086 bp) in 1.757 CPU sec, 1.768 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 279206, 17, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 286, 842)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2150)
[M::mem_pestat] mean and std.dev: (380.62, 285.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2804)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 309, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 917)
[M::mem_pestat] mean and std.dev: (330.40, 162.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1156)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (355, 802, 3965)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11185)
[M::mem_pestat] mean and std.dev: (1923.24, 2340.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14795)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 344, 961)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2527)
[M::mem_pestat] mean and std.dev: (571.67, 597.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3310)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 278937, 7, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 309, 539)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1257)
[M::mem_pestat] mean and std.dev: (375.77, 253.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1616)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 312, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 930)
[M::mem_pestat] mean and std.dev: (333.43, 163.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1173)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (259, 374, 451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 835)
[M::mem_pestat] mean and std.dev: (312.44, 105.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1027)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 685450 reads in 273.186 CPU sec, 8.737 real sec
[M::mem_process_seqs] Processed 684810 reads in 206.797 CPU sec, 6.658 real sec
[M::mem_process_seqs] Processed 684416 reads in 228.837 CPU sec, 7.380 real sec
sorting block 3, #reads = 1069614 mem = 536877922 peak = 878919680
[M::process] read 683648 sequences (100000077 bp) in 2.545 CPU sec, 2.717 real sec...
sorting block 4, #reads = 1069308 mem = 536883598 peak = 878919680
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 278602, 3, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 397, 484)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1066)
[M::mem_pestat] mean and std.dev: (341.38, 153.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1357)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 313, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 931)
[M::mem_pestat] mean and std.dev: (334.77, 164.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1174)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 317, 807)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2007)
[M::mem_pestat] mean and std.dev: (482.50, 368.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2607)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683690 sequences (100000190 bp) in 1.979 CPU sec, 2.033 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 278479, 22, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 771, 1599)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4371)
[M::mem_pestat] mean and std.dev: (948.33, 743.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5757)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 316, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 936)
[M::mem_pestat] mean and std.dev: (337.05, 164.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1180)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 631, 1904)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5264)
[M::mem_pestat] mean and std.dev: (1051.41, 981.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6944)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 284, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 916)
[M::mem_pestat] mean and std.dev: (305.56, 119.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1148)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683564 sequences (100000244 bp) in 1.780 CPU sec, 1.777 real sec...
[M::mem_process_seqs] Processed 684206 reads in 194.860 CPU sec, 6.183 real sec
[M::mem_process_seqs] Processed 683648 reads in 127.552 CPU sec, 4.039 real sec
sorting block 5, #reads = 1070466 mem = 536879736 peak = 878919680
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 278661, 16, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 294, 572)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1358)
[M::mem_pestat] mean and std.dev: (308.37, 195.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1751)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 317, 451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 945)
[M::mem_pestat] mean and std.dev: (338.60, 166.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1192)
[M::process] read 683180 sequences (100000241 bp) in 2.337 CPU sec, 2.497 real sec...
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (364, 580, 887)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1933)
[M::mem_pestat] mean and std.dev: (716.56, 466.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2583)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (258, 362, 641)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1407)
[M::mem_pestat] mean and std.dev: (484.56, 317.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1790)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683284 sequences (100000258 bp) in 1.241 CPU sec, 1.344 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 278546, 9, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 381, 419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 729)
[M::mem_pestat] mean and std.dev: (337.82, 126.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 884)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 317, 451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 945)
[M::mem_pestat] mean and std.dev: (338.42, 166.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1192)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 421, 742)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1866)
[M::mem_pestat] mean and std.dev: (413.22, 291.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2428)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683690 reads in 187.904 CPU sec, 5.995 real sec
[M::mem_process_seqs] Processed 683564 reads in 123.344 CPU sec, 3.953 real sec
sorting block 6, #reads = 1071058 mem = 536880647 peak = 878919680
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 278251, 10, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 235, 1715)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4795)
[M::mem_pestat] mean and std.dev: (660.71, 712.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6335)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 318, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 937)
[M::mem_pestat] mean and std.dev: (338.12, 164.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1181)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1776, 3861, 7125)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 17823)
[M::mem_pestat] mean and std.dev: (3554.80, 2588.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 23172)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 284, 795)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2011)
[M::mem_pestat] mean and std.dev: (399.40, 325.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2619)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683068 sequences (100000091 bp) in 2.271 CPU sec, 2.393 real sec...
[M::process] read 683374 sequences (100000188 bp) in 1.815 CPU sec, 1.817 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 277889, 22, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 428, 1005)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2551)
[M::mem_pestat] mean and std.dev: (620.79, 494.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3324)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 315, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 933)
[M::mem_pestat] mean and std.dev: (336.76, 164.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1176)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (318, 1172, 1467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3765)
[M::mem_pestat] mean and std.dev: (971.59, 710.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4914)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 248, 523)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1197)
[M::mem_pestat] mean and std.dev: (297.71, 161.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1534)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683180 reads in 192.174 CPU sec, 6.124 real sec
sorting block 7, #reads = 1069731 mem = 536881400 peak = 878919680
[M::process] read 683522 sequences (100000101 bp) in 1.953 CPU sec, 1.973 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 278075, 8, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 258, 530)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1208)
[M::mem_pestat] mean and std.dev: (314.23, 195.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1547)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 316, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 931)
[M::mem_pestat] mean and std.dev: (336.92, 163.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1173)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (277, 723, 1252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3202)
[M::mem_pestat] mean and std.dev: (757.29, 535.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4177)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683068 reads in 112.477 CPU sec, 3.815 real sec
sorting block 8, #reads = 1068801 mem = 536879972 peak = 878919680
[M::mem_process_seqs] Processed 683284 reads in 270.996 CPU sec, 8.877 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 278133, 15, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 273, 545)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1233)
[M::mem_pestat] mean and std.dev: (299.69, 204.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1577)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 315, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 927)
[M::mem_pestat] mean and std.dev: (335.33, 162.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1168)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 649, 4664)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13530)
[M::mem_pestat] mean and std.dev: (1626.80, 1889.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17963)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 258, 918)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2410)
[M::mem_pestat] mean and std.dev: (479.50, 524.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3156)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683602 sequences (100000023 bp) in 2.226 CPU sec, 2.405 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 278208, 11, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 289, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 958)
[M::mem_pestat] mean and std.dev: (300.59, 181.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1215)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 314, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 924)
[M::mem_pestat] mean and std.dev: (334.89, 163.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1164)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1044, 1804, 4409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11139)
[M::mem_pestat] mean and std.dev: (2078.27, 1622.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14504)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (262, 425, 1182)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3022)
[M::mem_pestat] mean and std.dev: (547.00, 531.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3942)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683336 sequences (100000058 bp) in 1.999 CPU sec, 2.002 real sec...
[M::mem_process_seqs] Processed 683374 reads in 212.961 CPU sec, 6.779 real sec
sorting block 9, #reads = 1067859 mem = 536878717 peak = 878919680
[M::mem_process_seqs] Processed 683522 reads in 127.022 CPU sec, 4.034 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 278249, 13, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 276, 766)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1872)
[M::mem_pestat] mean and std.dev: (418.46, 371.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2425)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 313, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 926)
[M::mem_pestat] mean and std.dev: (334.18, 163.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1167)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1547, 1547, 2705)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5021)
[M::mem_pestat] mean and std.dev: (1786.92, 931.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6179)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 306, 420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 834)
[M::mem_pestat] mean and std.dev: (334.25, 164.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1041)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683344 sequences (100000196 bp) in 2.308 CPU sec, 2.452 real sec...
[M::process] read 682988 sequences (100000191 bp) in 1.890 CPU sec, 1.886 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 277702, 18, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 358, 526)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1160)
[M::mem_pestat] mean and std.dev: (360.06, 214.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1477)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 312, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 929)
[M::mem_pestat] mean and std.dev: (334.50, 163.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1171)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (603, 1168, 1290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2664)
[M::mem_pestat] mean and std.dev: (951.31, 484.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3351)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 338, 505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1157)
[M::mem_pestat] mean and std.dev: (373.72, 238.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1483)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683602 reads in 192.034 CPU sec, 6.125 real sec
sorting block 10, #reads = 1068534 mem = 536878762 peak = 878919680
[M::mem_process_seqs] Processed 683336 reads in 133.598 CPU sec, 4.277 real sec
sorting block 11, #reads = 1069341 mem = 536880291 peak = 878919680
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 278255, 8, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 259, 483)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1099)
[M::mem_pestat] mean and std.dev: (279.39, 155.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1407)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 315, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 936)
[M::mem_pestat] mean and std.dev: (336.81, 164.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1180)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (312, 409, 573)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1095)
[M::mem_pestat] mean and std.dev: (420.83, 162.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1356)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682472 sequences (100000153 bp) in 2.424 CPU sec, 2.587 real sec...
[M::process] read 682768 sequences (100000121 bp) in 2.130 CPU sec, 2.134 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 278046, 9, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 360, 607)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1441)
[M::mem_pestat] mean and std.dev: (407.67, 293.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1858)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 315, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 931)
[M::mem_pestat] mean and std.dev: (336.71, 164.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1173)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (266, 446, 647)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1409)
[M::mem_pestat] mean and std.dev: (456.79, 284.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1790)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683344 reads in 194.267 CPU sec, 6.187 real sec
[M::mem_process_seqs] Processed 682988 reads in 126.571 CPU sec, 4.019 real sec
sorting block 12, #reads = 1069356 mem = 536878483 peak = 878919680
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 277816, 10, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 287, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 970)
[M::mem_pestat] mean and std.dev: (300.40, 156.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1234)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 320, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 945)
[M::mem_pestat] mean and std.dev: (340.38, 165.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1191)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (94, 493, 830)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2302)
[M::mem_pestat] mean and std.dev: (465.44, 331.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3038)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 339, 420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 890)
[M::mem_pestat] mean and std.dev: (319.88, 153.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1125)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682000 sequences (100000081 bp) in 2.896 CPU sec, 3.140 real sec...
[M::process] read 682094 sequences (100000227 bp) in 1.850 CPU sec, 1.853 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 277412, 9, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (291, 571, 1016)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2466)
[M::mem_pestat] mean and std.dev: (633.45, 375.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3191)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 316, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 926)
[M::mem_pestat] mean and std.dev: (336.61, 163.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1166)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 285, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 982)
[M::mem_pestat] mean and std.dev: (316.43, 188.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1245)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682472 reads in 195.846 CPU sec, 6.250 real sec
sorting block 13, #reads = 1068605 mem = 536879810 peak = 878919680
[M::process] read 682326 sequences (100000101 bp) in 1.553 CPU sec, 1.554 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 277778, 5, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (337, 366, 521)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 889)
[M::mem_pestat] mean and std.dev: (385.80, 189.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1145)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 321, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 932)
[M::mem_pestat] mean and std.dev: (340.39, 163.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1173)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 275, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1035)
[M::mem_pestat] mean and std.dev: (276.19, 133.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1335)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682000 reads in 111.731 CPU sec, 3.572 real sec
[M::mem_process_seqs] Processed 682768 reads in 275.415 CPU sec, 8.824 real sec
sorting block 14, #reads = 1069075 mem = 536880696 peak = 878919680
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 278036, 13, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 342, 816)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2090)
[M::mem_pestat] mean and std.dev: (431.60, 345.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2727)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 321, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 930)
[M::mem_pestat] mean and std.dev: (340.59, 163.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1170)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (66, 414, 2362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6954)
[M::mem_pestat] mean and std.dev: (1045.42, 1288.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9250)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 349, 953)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2391)
[M::mem_pestat] mean and std.dev: (631.58, 590.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3110)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681684 sequences (100000218 bp) in 2.802 CPU sec, 2.949 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 278280, 7, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 312, 547)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1325)
[M::mem_pestat] mean and std.dev: (320.49, 211.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1714)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 321, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 929)
[M::mem_pestat] mean and std.dev: (339.44, 162.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1169)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 362, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 867)
[M::mem_pestat] mean and std.dev: (313.72, 140.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1080)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681658 sequences (100000064 bp) in 1.805 CPU sec, 1.807 real sec...
[M::mem_process_seqs] Processed 682094 reads in 219.980 CPU sec, 7.011 real sec
[M::mem_process_seqs] Processed 682326 reads in 131.008 CPU sec, 4.156 real sec
sorting block 15, #reads = 1067521 mem = 536881987 peak = 878919680
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 277523, 15, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (255, 381, 620)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1350)
[M::mem_pestat] mean and std.dev: (392.89, 241.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1715)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 324, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 937)
[M::mem_pestat] mean and std.dev: (342.87, 164.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1179)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (379, 852, 2221)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5905)
[M::mem_pestat] mean and std.dev: (1414.20, 1236.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7747)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 305, 552)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1182)
[M::mem_pestat] mean and std.dev: (315.83, 155.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1497)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681606 sequences (100000275 bp) in 2.614 CPU sec, 2.826 real sec...
[M::process] read 681084 sequences (100000166 bp) in 1.758 CPU sec, 1.761 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 277085, 16, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 353, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 961)
[M::mem_pestat] mean and std.dev: (341.42, 190.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1221)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 327, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 950)
[M::mem_pestat] mean and std.dev: (345.89, 167.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1196)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (492, 515, 1662)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4002)
[M::mem_pestat] mean and std.dev: (919.50, 874.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5172)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 273, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 629)
[M::mem_pestat] mean and std.dev: (264.96, 99.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 773)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681684 reads in 196.896 CPU sec, 6.305 real sec
sorting block 16, #reads = 1068401 mem = 536878493 peak = 878919680
[M::mem_process_seqs] Processed 681658 reads in 130.036 CPU sec, 4.167 real sec
sorting block 17, #reads = 1068477 mem = 536883669 peak = 878919680
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 277655, 8, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 295, 509)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1211)
[M::mem_pestat] mean and std.dev: (261.92, 134.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1562)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 327, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 953)
[M::mem_pestat] mean and std.dev: (346.60, 167.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1200)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (319, 470, 1233)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3061)
[M::mem_pestat] mean and std.dev: (594.77, 545.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3975)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681448 sequences (100000088 bp) in 2.907 CPU sec, 3.103 real sec...
[M::process] read 687414 sequences (100000228 bp) in 1.866 CPU sec, 1.868 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 277553, 17, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 504, 1196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3116)
[M::mem_pestat] mean and std.dev: (794.30, 774.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4076)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 330, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 961)
[M::mem_pestat] mean and std.dev: (349.17, 168.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1210)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (384, 1424, 4714)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13374)
[M::mem_pestat] mean and std.dev: (2249.82, 2459.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17704)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (284, 413, 751)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1685)
[M::mem_pestat] mean and std.dev: (455.69, 239.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2152)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681606 reads in 193.446 CPU sec, 6.168 real sec
[M::mem_process_seqs] Processed 681084 reads in 123.884 CPU sec, 3.954 real sec
sorting block 18, #reads = 1070202 mem = 536880851 peak = 878919680
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 278348, 19, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 236, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 525)
[M::mem_pestat] mean and std.dev: (233.65, 86.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 637)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 330, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 958)
[M::mem_pestat] mean and std.dev: (348.94, 168.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1206)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1389, 2377, 3929)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9009)
[M::mem_pestat] mean and std.dev: (2653.95, 2149.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11549)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 511, 733)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1745)
[M::mem_pestat] mean and std.dev: (398.79, 214.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2251)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 686634 sequences (100000035 bp) in 2.536 CPU sec, 2.719 real sec...
[M::process] read 686162 sequences (100000203 bp) in 1.851 CPU sec, 1.854 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 279622, 7, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 386, 621)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1485)
[M::mem_pestat] mean and std.dev: (377.59, 210.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1917)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 297, 427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 899)
[M::mem_pestat] mean and std.dev: (320.43, 159.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1135)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (280, 338, 532)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1036)
[M::mem_pestat] mean and std.dev: (356.53, 160.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1288)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681448 reads in 193.690 CPU sec, 6.229 real sec
[M::mem_process_seqs] Processed 687414 reads in 131.571 CPU sec, 4.246 real sec
sorting block 19, #reads = 1068173 mem = 536879212 peak = 878919680
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 278948, 6, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (275, 360, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 818)
[M::mem_pestat] mean and std.dev: (334.31, 131.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 999)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 302, 434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 914)
[M::mem_pestat] mean and std.dev: (324.57, 161.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1154)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 278, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 581)
[M::mem_pestat] mean and std.dev: (233.07, 67.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 708)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 686272 sequences (100000114 bp) in 2.560 CPU sec, 3.066 real sec...
[M::process] read 685804 sequences (100000159 bp) in 1.980 CPU sec, 1.992 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 279694, 5, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 238, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 802)
[M::mem_pestat] mean and std.dev: (208.91, 90.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1025)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 304, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 918)
[M::mem_pestat] mean and std.dev: (326.70, 162.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1159)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 335, 575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1301)
[M::mem_pestat] mean and std.dev: (347.89, 267.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1664)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 686634 reads in 197.586 CPU sec, 6.598 real sec
[M::mem_process_seqs] Processed 686162 reads in 131.421 CPU sec, 4.269 real sec
sorting block 20, #reads = 1073053 mem = 536880382 peak = 878919680
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 279048, 12, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 296, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 986)
[M::mem_pestat] mean and std.dev: (308.72, 176.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1246)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 304, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 915)
[M::mem_pestat] mean and std.dev: (326.43, 162.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1155)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (944, 1117, 1837)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3623)
[M::mem_pestat] mean and std.dev: (1159.25, 828.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4516)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 260, 387)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 783)
[M::mem_pestat] mean and std.dev: (272.88, 117.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 981)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 685660 sequences (100000233 bp) in 2.570 CPU sec, 2.708 real sec...
[M::process] read 685244 sequences (100000099 bp) in 1.810 CPU sec, 1.816 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 279465, 10, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 259, 399)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 855)
[M::mem_pestat] mean and std.dev: (288.43, 163.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1083)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 305, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 916)
[M::mem_pestat] mean and std.dev: (327.32, 162.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1156)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (671, 757, 760)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (493, 938)
[M::mem_pestat] mean and std.dev: (720.57, 42.94)
[M::mem_pestat] low and high boundaries for proper pairs: (404, 1027)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 360, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 868)
[M::mem_pestat] mean and std.dev: (355.07, 163.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1082)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 686272 reads in 199.995 CPU sec, 6.657 real sec
sorting block 21, #reads = 1072100 mem = 536880725 peak = 878919680
[M::mem_process_seqs] Processed 685804 reads in 131.799 CPU sec, 4.571 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 279201, 4, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 279, 495)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1133)
[M::mem_pestat] mean and std.dev: (274.50, 174.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1452)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 307, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 920)
[M::mem_pestat] mean and std.dev: (329.08, 162.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1161)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 413, 726)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1752)
[M::mem_pestat] mean and std.dev: (587.18, 526.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2692)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 22, #reads = 1072557 mem = 536883789 peak = 913903616
[M::process] read 684550 sequences (100000228 bp) in 2.663 CPU sec, 2.887 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 278826, 15, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (130, 231, 510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1270)
[M::mem_pestat] mean and std.dev: (314.04, 255.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1650)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 310, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 928)
[M::mem_pestat] mean and std.dev: (331.99, 164.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1171)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (412, 496, 1441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3499)
[M::mem_pestat] mean and std.dev: (877.67, 821.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4528)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 265, 484)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1148)
[M::mem_pestat] mean and std.dev: (291.10, 202.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1480)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 684368 sequences (100000249 bp) in 2.042 CPU sec, 2.107 real sec...
[M::mem_process_seqs] Processed 685660 reads in 204.779 CPU sec, 6.803 real sec
[M::mem_process_seqs] Processed 685244 reads in 135.772 CPU sec, 4.538 real sec
sorting block 23, #reads = 1072656 mem = 536880703 peak = 913903616
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 278419, 13, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (254, 464, 624)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1364)
[M::mem_pestat] mean and std.dev: (467.26, 295.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1734)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 312, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 933)
[M::mem_pestat] mean and std.dev: (333.80, 164.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1177)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (583, 583, 1253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2593)
[M::mem_pestat] mean and std.dev: (830.23, 495.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3263)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 263, 476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1016)
[M::mem_pestat] mean and std.dev: (302.65, 141.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1286)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683944 sequences (100000036 bp) in 3.051 CPU sec, 3.310 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 278346, 2, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 279, 400)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 888)
[M::mem_pestat] mean and std.dev: (295.92, 177.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1132)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 316, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 938)
[M::mem_pestat] mean and std.dev: (336.33, 165.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1183)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 299, 895)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2279)
[M::mem_pestat] mean and std.dev: (554.85, 546.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2971)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683882 sequences (100000175 bp) in 2.078 CPU sec, 2.078 real sec...
[M::mem_process_seqs] Processed 684550 reads in 208.677 CPU sec, 6.812 real sec
[M::mem_process_seqs] Processed 684368 reads in 135.423 CPU sec, 4.409 real sec
sorting block 24, #reads = 1071282 mem = 536880307 peak = 913903616
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 278676, 8, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 273, 565)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1275)
[M::mem_pestat] mean and std.dev: (341.11, 192.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1630)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 318, 451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 945)
[M::mem_pestat] mean and std.dev: (338.16, 166.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1192)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 379, 489)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 971)
[M::mem_pestat] mean and std.dev: (394.23, 226.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1299)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683736 sequences (100000019 bp) in 2.657 CPU sec, 2.924 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 279221, 9, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 415, 647)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1451)
[M::mem_pestat] mean and std.dev: (437.73, 283.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1853)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 320, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 955)
[M::mem_pestat] mean and std.dev: (340.37, 167.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1205)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 235, 557)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1345)
[M::mem_pestat] mean and std.dev: (295.20, 182.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1739)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683718 sequences (100000280 bp) in 1.948 CPU sec, 1.953 real sec...
[M::mem_process_seqs] Processed 683944 reads in 200.421 CPU sec, 6.489 real sec
sorting block 25, #reads = 1071362 mem = 536878352 peak = 913903616
[M::mem_process_seqs] Processed 683882 reads in 134.292 CPU sec, 4.341 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 278454, 14, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 356, 535)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1209)
[M::mem_pestat] mean and std.dev: (307.35, 156.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1546)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 318, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 950)
[M::mem_pestat] mean and std.dev: (338.85, 166.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1199)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (373, 755, 1236)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2962)
[M::mem_pestat] mean and std.dev: (915.86, 645.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3825)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 385, 622)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1358)
[M::mem_pestat] mean and std.dev: (399.35, 215.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1726)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683538 sequences (100000065 bp) in 2.537 CPU sec, 2.816 real sec...
sorting block 26, #reads = 1069741 mem = 536880766 peak = 915091456
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 278606, 16, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 259, 479)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1127)
[M::mem_pestat] mean and std.dev: (326.61, 233.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1451)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 320, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 955)
[M::mem_pestat] mean and std.dev: (340.97, 167.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1205)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (431, 1484, 2149)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5585)
[M::mem_pestat] mean and std.dev: (1365.19, 847.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7303)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 309, 503)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1045)
[M::mem_pestat] mean and std.dev: (317.24, 164.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1316)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683744 sequences (100000292 bp) in 1.807 CPU sec, 1.827 real sec...
[M::mem_process_seqs] Processed 683736 reads in 202.950 CPU sec, 6.559 real sec
[M::mem_process_seqs] Processed 683718 reads in 136.731 CPU sec, 4.412 real sec
sorting block 27, #reads = 1070374 mem = 536883614 peak = 915091456
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 278342, 17, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 411, 742)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1888)
[M::mem_pestat] mean and std.dev: (462.86, 394.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2461)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 318, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 951)
[M::mem_pestat] mean and std.dev: (339.65, 167.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1200)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (254, 254, 929)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2279)
[M::mem_pestat] mean and std.dev: (451.19, 496.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2954)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 364, 866)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2192)
[M::mem_pestat] mean and std.dev: (579.21, 583.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2913)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683606 sequences (100000060 bp) in 3.040 CPU sec, 3.252 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 277674, 20, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (261, 362, 767)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1779)
[M::mem_pestat] mean and std.dev: (470.05, 353.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2285)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 315, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 944)
[M::mem_pestat] mean and std.dev: (337.84, 167.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1191)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (337, 444, 1109)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2653)
[M::mem_pestat] mean and std.dev: (594.37, 537.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3425)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (275, 336, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 860)
[M::mem_pestat] mean and std.dev: (314.50, 136.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1055)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683584 sequences (100000114 bp) in 1.898 CPU sec, 1.906 real sec...
[M::mem_process_seqs] Processed 683538 reads in 199.808 CPU sec, 6.395 real sec
[M::mem_process_seqs] Processed 683744 reads in 135.593 CPU sec, 4.316 real sec
sorting block 28, #reads = 1069608 mem = 536879705 peak = 915091456
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 278550, 25, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 299, 578)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1234)
[M::mem_pestat] mean and std.dev: (357.39, 193.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1562)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 317, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 951)
[M::mem_pestat] mean and std.dev: (339.18, 167.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1200)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (55, 278, 982)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2836)
[M::mem_pestat] mean and std.dev: (735.04, 867.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4203)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 577, 1525)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4077)
[M::mem_pestat] mean and std.dev: (730.37, 618.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5353)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 684100 sequences (100000080 bp) in 2.906 CPU sec, 3.021 real sec...
[M::process] read 683860 sequences (100000202 bp) in 1.870 CPU sec, 1.874 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 278768, 14, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (125, 222, 535)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1355)
[M::mem_pestat] mean and std.dev: (269.28, 179.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1765)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 314, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 932)
[M::mem_pestat] mean and std.dev: (335.50, 164.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1175)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (832, 4981, 7589)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 21103)
[M::mem_pestat] mean and std.dev: (3876.57, 2892.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 27860)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (270, 378, 484)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 912)
[M::mem_pestat] mean and std.dev: (342.79, 122.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1126)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683606 reads in 188.191 CPU sec, 5.973 real sec
sorting block 29, #reads = 1068881 mem = 536882318 peak = 915091456
[M::mem_process_seqs] Processed 683584 reads in 124.796 CPU sec, 3.958 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 278613, 16, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 308, 876)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2162)
[M::mem_pestat] mean and std.dev: (444.69, 394.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2805)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 311, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 919)
[M::mem_pestat] mean and std.dev: (332.11, 162.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1158)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (585, 910, 1994)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4812)
[M::mem_pestat] mean and std.dev: (1170.88, 835.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6221)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 296, 557)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1213)
[M::mem_pestat] mean and std.dev: (354.00, 247.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1541)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683604 sequences (100000072 bp) in 2.724 CPU sec, 2.870 real sec...
[M::process] read 683526 sequences (100000262 bp) in 1.888 CPU sec, 1.893 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 277917, 11, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 337, 748)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1824)
[M::mem_pestat] mean and std.dev: (511.59, 404.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2362)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 310, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 919)
[M::mem_pestat] mean and std.dev: (331.71, 161.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1158)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (741, 823, 1244)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2250)
[M::mem_pestat] mean and std.dev: (840.80, 430.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2753)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (280, 403, 508)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 964)
[M::mem_pestat] mean and std.dev: (392.95, 185.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1192)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684100 reads in 191.569 CPU sec, 6.089 real sec
sorting block 30, #reads = 1071412 mem = 536879624 peak = 915091456
[M::mem_process_seqs] Processed 683860 reads in 128.378 CPU sec, 4.073 real sec
sorting block 31, #reads = 1069310 mem = 536878748 peak = 998510592
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 278073, 7, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 236, 510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1166)
[M::mem_pestat] mean and std.dev: (274.50, 166.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1494)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 311, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 919)
[M::mem_pestat] mean and std.dev: (332.50, 162.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1158)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 350, 559)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1203)
[M::mem_pestat] mean and std.dev: (424.91, 264.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1525)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683312 sequences (100000136 bp) in 2.535 CPU sec, 2.640 real sec...
[M::process] read 683146 sequences (100000012 bp) in 1.920 CPU sec, 1.923 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 278009, 17, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 396, 630)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1438)
[M::mem_pestat] mean and std.dev: (374.04, 242.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1842)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 313, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 920)
[M::mem_pestat] mean and std.dev: (333.86, 162.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1159)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (479, 540, 1876)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4670)
[M::mem_pestat] mean and std.dev: (1225.35, 1350.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6628)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 369, 515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1119)
[M::mem_pestat] mean and std.dev: (351.00, 160.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1421)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683604 reads in 197.946 CPU sec, 6.396 real sec
[M::mem_process_seqs] Processed 683526 reads in 132.119 CPU sec, 4.210 real sec
sorting block 32, #reads = 1068931 mem = 536878766 peak = 998510592
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 278489, 11, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (282, 450, 532)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1032)
[M::mem_pestat] mean and std.dev: (420.39, 176.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1282)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 314, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 921)
[M::mem_pestat] mean and std.dev: (334.68, 162.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1160)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (417, 417, 632)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1062)
[M::mem_pestat] mean and std.dev: (467.91, 187.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1277)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 288, 571)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1265)
[M::mem_pestat] mean and std.dev: (430.92, 305.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1654)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683204 sequences (100000164 bp) in 2.505 CPU sec, 2.654 real sec...
[M::process] read 682520 sequences (100000113 bp) in 1.897 CPU sec, 1.901 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 277857, 15, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 286, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 629)
[M::mem_pestat] mean and std.dev: (273.03, 129.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 793)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 313, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 913)
[M::mem_pestat] mean and std.dev: (333.89, 161.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1149)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (345, 528, 773)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1629)
[M::mem_pestat] mean and std.dev: (564.36, 452.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2373)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (271, 305, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 829)
[M::mem_pestat] mean and std.dev: (300.39, 109.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1015)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683312 reads in 197.160 CPU sec, 6.294 real sec
[M::mem_process_seqs] Processed 683146 reads in 131.557 CPU sec, 4.194 real sec
sorting block 33, #reads = 1068794 mem = 536880533 peak = 998510592
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 279156, 14, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 333, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 933)
[M::mem_pestat] mean and std.dev: (321.36, 193.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1184)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 315, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 928)
[M::mem_pestat] mean and std.dev: (336.36, 163.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1169)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (707, 1445, 2286)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5444)
[M::mem_pestat] mean and std.dev: (1142.75, 784.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7023)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 351, 481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1017)
[M::mem_pestat] mean and std.dev: (374.50, 212.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1285)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682622 sequences (100000069 bp) in 2.811 CPU sec, 2.937 real sec...
[M::process] read 682248 sequences (100000236 bp) in 1.936 CPU sec, 1.943 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 277786, 7, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 315, 582)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1290)
[M::mem_pestat] mean and std.dev: (366.73, 194.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1644)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 319, 451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 939)
[M::mem_pestat] mean and std.dev: (339.96, 165.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1183)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 289, 422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 876)
[M::mem_pestat] mean and std.dev: (259.94, 122.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1103)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683204 reads in 196.169 CPU sec, 6.250 real sec
sorting block 34, #reads = 1068951 mem = 536882103 peak = 998510592
[M::mem_process_seqs] Processed 682520 reads in 132.003 CPU sec, 4.193 real sec
sorting block 35, #reads = 1068867 mem = 536880473 peak = 998510592
[M::process] read 682262 sequences (100000105 bp) in 2.760 CPU sec, 2.900 real sec...
[M::process] read 682188 sequences (100000104 bp) in 1.930 CPU sec, 1.940 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 278018, 15, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 307, 825)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2001)
[M::mem_pestat] mean and std.dev: (471.37, 391.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2589)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 321, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 941)
[M::mem_pestat] mean and std.dev: (342.23, 166.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1185)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 565, 1071)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2849)
[M::mem_pestat] mean and std.dev: (561.33, 366.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3738)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 259, 565)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1293)
[M::mem_pestat] mean and std.dev: (338.37, 234.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1657)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682262 reads in 104.900 CPU sec, 3.566 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 278297, 11, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (292, 363, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 766)
[M::mem_pestat] mean and std.dev: (350.62, 139.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 924)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 320, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 945)
[M::mem_pestat] mean and std.dev: (341.25, 166.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1191)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (670, 818, 2263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5449)
[M::mem_pestat] mean and std.dev: (1228.40, 1324.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7042)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 344, 522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1142)
[M::mem_pestat] mean and std.dev: (336.12, 172.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1452)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682248 reads in 222.373 CPU sec, 7.882 real sec
sorting block 36, #reads = 1068477 mem = 536878718 peak = 998510592
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 278206, 19, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 266, 379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 851)
[M::mem_pestat] mean and std.dev: (276.42, 170.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1087)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 320, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 945)
[M::mem_pestat] mean and std.dev: (341.06, 166.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1191)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 245, 1165)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3005)
[M::mem_pestat] mean and std.dev: (509.44, 418.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3925)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 350, 521)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1161)
[M::mem_pestat] mean and std.dev: (395.85, 275.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1499)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682140 sequences (100000114 bp) in 3.034 CPU sec, 3.195 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 278374, 6, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 265, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 934)
[M::mem_pestat] mean and std.dev: (296.85, 151.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1185)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 322, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 952)
[M::mem_pestat] mean and std.dev: (343.40, 167.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1200)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (260, 353, 493)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 959)
[M::mem_pestat] mean and std.dev: (358.33, 181.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1192)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682622 reads in 413.041 CPU sec, 13.952 real sec
[M::mem_process_seqs] Processed 682188 reads in 155.970 CPU sec, 4.933 real sec
[M::process] read 682216 sequences (100000275 bp) in 2.264 CPU sec, 2.341 real sec...
sorting block 37, #reads = 1069087 mem = 536877736 peak = 998510592
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 278256, 1, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 256, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 711)
[M::mem_pestat] mean and std.dev: (235.27, 89.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 891)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 323, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 959)
[M::mem_pestat] mean and std.dev: (344.95, 169.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1209)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 382, 816)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1950)
[M::mem_pestat] mean and std.dev: (412.62, 252.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2517)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 688180 sequences (100000195 bp) in 2.692 CPU sec, 2.838 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 278931, 7, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 309, 1644)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4448)
[M::mem_pestat] mean and std.dev: (896.50, 1025.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5850)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 326, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 971)
[M::mem_pestat] mean and std.dev: (347.70, 171.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1225)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 407, 1027)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2705)
[M::mem_pestat] mean and std.dev: (590.24, 517.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3544)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 687984 sequences (100000299 bp) in 1.919 CPU sec, 1.926 real sec...
[M::mem_process_seqs] Processed 682140 reads in 198.093 CPU sec, 6.310 real sec
[M::mem_process_seqs] Processed 682216 reads in 134.144 CPU sec, 4.256 real sec
sorting block 38, #reads = 1067908 mem = 536882648 peak = 998510592
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 279901, 13, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 245, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 759)
[M::mem_pestat] mean and std.dev: (252.44, 112.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 957)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 292, 420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 884)
[M::mem_pestat] mean and std.dev: (314.78, 156.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1116)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1284, 1921, 2212)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4068)
[M::mem_pestat] mean and std.dev: (1725.92, 542.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4996)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 364, 1676)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4612)
[M::mem_pestat] mean and std.dev: (743.51, 768.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6080)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 688218 sequences (100000189 bp) in 2.717 CPU sec, 2.846 real sec...
[M::process] read 687850 sequences (100000071 bp) in 1.824 CPU sec, 1.829 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 279450, 6, 19)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 351, 495)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1037)
[M::mem_pestat] mean and std.dev: (400.26, 244.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1379)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 295, 424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 894)
[M::mem_pestat] mean and std.dev: (316.89, 157.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1129)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 215, 282)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 546)
[M::mem_pestat] mean and std.dev: (210.47, 86.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 678)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 688180 reads in 199.045 CPU sec, 6.356 real sec
sorting block 39, #reads = 1068105 mem = 536881919 peak = 998510592
[M::mem_process_seqs] Processed 687984 reads in 132.836 CPU sec, 4.221 real sec
sorting block 40, #reads = 1072080 mem = 536879307 peak = 1054302208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 279116, 13, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 221, 681)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1679)
[M::mem_pestat] mean and std.dev: (418.13, 418.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2178)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 294, 422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 888)
[M::mem_pestat] mean and std.dev: (315.96, 156.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1121)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (84, 261, 1420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4092)
[M::mem_pestat] mean and std.dev: (396.00, 509.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5428)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 588, 1485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3989)
[M::mem_pestat] mean and std.dev: (971.03, 933.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5241)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 686842 sequences (100000214 bp) in 2.615 CPU sec, 2.768 real sec...
[M::process] read 686320 sequences (100000182 bp) in 1.897 CPU sec, 1.906 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 279667, 25, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 301, 428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 886)
[M::mem_pestat] mean and std.dev: (272.14, 107.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1115)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 295, 424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 892)
[M::mem_pestat] mean and std.dev: (317.16, 156.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1126)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (97, 1158, 2046)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5944)
[M::mem_pestat] mean and std.dev: (948.35, 851.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7893)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 374, 425)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 865)
[M::mem_pestat] mean and std.dev: (314.60, 123.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1085)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 688218 reads in 202.159 CPU sec, 6.450 real sec
[M::mem_process_seqs] Processed 687850 reads in 133.638 CPU sec, 4.257 real sec
sorting block 41, #reads = 1071519 mem = 536878090 peak = 1054302208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 279169, 10, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 267, 425)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 933)
[M::mem_pestat] mean and std.dev: (332.57, 215.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1193)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 299, 425)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 889)
[M::mem_pestat] mean and std.dev: (318.95, 155.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1121)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (307, 837, 2065)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5581)
[M::mem_pestat] mean and std.dev: (1033.50, 817.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7339)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 551, 804)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1934)
[M::mem_pestat] mean and std.dev: (535.12, 371.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2499)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 685830 sequences (100000120 bp) in 2.565 CPU sec, 2.761 real sec...
[M::process] read 685400 sequences (100000128 bp) in 1.477 CPU sec, 1.481 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 279160, 6, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 217, 283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 535)
[M::mem_pestat] mean and std.dev: (220.49, 104.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 661)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 303, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 900)
[M::mem_pestat] mean and std.dev: (322.82, 157.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1135)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (306, 692, 1123)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2757)
[M::mem_pestat] mean and std.dev: (629.09, 427.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3574)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 686842 reads in 201.085 CPU sec, 6.439 real sec
[M::mem_process_seqs] Processed 686320 reads in 134.032 CPU sec, 4.293 real sec
sorting block 42, #reads = 1072387 mem = 536887541 peak = 1054302208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 279358, 15, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 240, 395)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 849)
[M::mem_pestat] mean and std.dev: (293.72, 178.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1076)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 306, 433)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 905)
[M::mem_pestat] mean and std.dev: (325.13, 158.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1141)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (13, 127, 816)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2422)
[M::mem_pestat] mean and std.dev: (332.07, 365.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3225)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 496, 721)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1671)
[M::mem_pestat] mean and std.dev: (440.97, 248.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2146)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 685036 sequences (100000299 bp) in 2.544 CPU sec, 2.700 real sec...
[M::process] read 684628 sequences (100000191 bp) in 1.708 CPU sec, 1.719 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 278741, 7, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 485, 745)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1863)
[M::mem_pestat] mean and std.dev: (463.65, 363.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2422)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 308, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 909)
[M::mem_pestat] mean and std.dev: (326.88, 158.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1146)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (277, 518, 1503)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3955)
[M::mem_pestat] mean and std.dev: (730.44, 568.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5181)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 685830 reads in 197.327 CPU sec, 6.288 real sec
sorting block 43, #reads = 1070668 mem = 536879143 peak = 1054302208
[M::mem_process_seqs] Processed 685400 reads in 127.914 CPU sec, 4.071 real sec
sorting block 44, #reads = 1070417 mem = 536878912 peak = 1054302208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 278614, 5, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 326, 1007)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2539)
[M::mem_pestat] mean and std.dev: (387.60, 301.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3305)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 309, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 908)
[M::mem_pestat] mean and std.dev: (328.23, 158.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1144)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (275, 466, 752)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1706)
[M::mem_pestat] mean and std.dev: (496.54, 311.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2183)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683938 sequences (100000122 bp) in 2.592 CPU sec, 2.743 real sec...
[M::process] read 683972 sequences (100000023 bp) in 1.893 CPU sec, 1.900 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 278423, 7, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 346, 665)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1655)
[M::mem_pestat] mean and std.dev: (368.22, 226.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2150)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 310, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 918)
[M::mem_pestat] mean and std.dev: (329.92, 159.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1157)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 357, 718)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1694)
[M::mem_pestat] mean and std.dev: (446.52, 319.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2182)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 685036 reads in 191.951 CPU sec, 6.106 real sec
[M::process] read 684162 sequences (100000071 bp) in 2.253 CPU sec, 2.254 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 278226, 10, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 286, 880)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2162)
[M::mem_pestat] mean and std.dev: (353.21, 231.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2803)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 315, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 918)
[M::mem_pestat] mean and std.dev: (333.45, 160.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1156)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (35, 655, 1213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3569)
[M::mem_pestat] mean and std.dev: (611.10, 533.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4747)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 339, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 663)
[M::mem_pestat] mean and std.dev: (282.84, 103.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 811)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683938 reads in 112.973 CPU sec, 3.580 real sec
sorting block 45, #reads = 1071041 mem = 536879395 peak = 1054302208
[M::mem_process_seqs] Processed 684628 reads in 291.420 CPU sec, 9.283 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 278177, 31, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 220, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 721)
[M::mem_pestat] mean and std.dev: (249.46, 125.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 910)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 314, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 917)
[M::mem_pestat] mean and std.dev: (332.11, 159.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1155)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 1300, 2252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6326)
[M::mem_pestat] mean and std.dev: (1481.13, 1308.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8363)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 277, 399)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709)
[M::mem_pestat] mean and std.dev: (308.47, 122.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 46, #reads = 1071174 mem = 536880970 peak = 1054302208
[M::process] read 683530 sequences (100000057 bp) in 3.018 CPU sec, 3.223 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 278405, 14, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 207, 674)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1744)
[M::mem_pestat] mean and std.dev: (357.98, 386.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2279)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 315, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 928)
[M::mem_pestat] mean and std.dev: (333.54, 161.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1170)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (295, 747, 8975)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 26335)
[M::mem_pestat] mean and std.dev: (3104.29, 4060.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 35015)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (262, 324, 606)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1294)
[M::mem_pestat] mean and std.dev: (390.03, 205.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1638)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683972 reads in 226.237 CPU sec, 7.211 real sec
[M::process] read 683792 sequences (100000071 bp) in 2.107 CPU sec, 2.149 real sec...
[M::mem_process_seqs] Processed 684162 reads in 137.577 CPU sec, 4.346 real sec
sorting block 47, #reads = 1070285 mem = 536875545 peak = 1054302208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 278815, 8, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 272, 496)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1150)
[M::mem_pestat] mean and std.dev: (329.61, 183.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1477)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 316, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 930)
[M::mem_pestat] mean and std.dev: (335.69, 162.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1172)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 460, 644)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1474)
[M::mem_pestat] mean and std.dev: (443.46, 252.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1889)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 684234 sequences (100000159 bp) in 2.675 CPU sec, 2.848 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 278825, 11, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 339, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 966)
[M::mem_pestat] mean and std.dev: (288.91, 141.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1224)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 315, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 927)
[M::mem_pestat] mean and std.dev: (334.79, 162.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1168)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (46, 265, 5523)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 16477)
[M::mem_pestat] mean and std.dev: (1982.45, 2930.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 21954)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (301, 376, 495)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 883)
[M::mem_pestat] mean and std.dev: (367.36, 136.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1077)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683722 sequences (100000188 bp) in 2.027 CPU sec, 2.034 real sec...
[M::mem_process_seqs] Processed 683530 reads in 201.945 CPU sec, 6.444 real sec
[M::mem_process_seqs] Processed 683792 reads in 135.385 CPU sec, 4.297 real sec
sorting block 48, #reads = 1069958 mem = 536881231 peak = 1054302208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 278862, 14, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 349, 552)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1242)
[M::mem_pestat] mean and std.dev: (387.25, 221.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1587)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 310, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 915)
[M::mem_pestat] mean and std.dev: (330.79, 161.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1153)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (429, 998, 1366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3240)
[M::mem_pestat] mean and std.dev: (852.92, 515.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4177)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 312, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 932)
[M::mem_pestat] mean and std.dev: (347.51, 155.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1162)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683594 sequences (100000299 bp) in 2.614 CPU sec, 2.766 real sec...
[M::process] read 683832 sequences (100000012 bp) in 1.942 CPU sec, 1.948 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 278178, 11, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 217, 477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1157)
[M::mem_pestat] mean and std.dev: (292.83, 216.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1497)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 312, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 920)
[M::mem_pestat] mean and std.dev: (332.73, 161.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1159)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (914, 1897, 4692)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12248)
[M::mem_pestat] mean and std.dev: (2717.27, 2118.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16026)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 363, 677)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1547)
[M::mem_pestat] mean and std.dev: (434.14, 240.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1982)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684234 reads in 197.234 CPU sec, 6.283 real sec
[M::mem_process_seqs] Processed 683722 reads in 128.543 CPU sec, 4.077 real sec
sorting block 49, #reads = 1069456 mem = 536878464 peak = 1054302208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 278415, 15, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (129, 228, 390)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 912)
[M::mem_pestat] mean and std.dev: (243.74, 147.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1173)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 313, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 918)
[M::mem_pestat] mean and std.dev: (333.39, 161.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1156)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (289, 447, 665)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1417)
[M::mem_pestat] mean and std.dev: (445.62, 249.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1793)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 368, 991)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2527)
[M::mem_pestat] mean and std.dev: (618.78, 576.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3295)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683632 sequences (100000015 bp) in 2.516 CPU sec, 2.614 real sec...
[M::process] read 683266 sequences (100000045 bp) in 1.950 CPU sec, 1.945 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 277910, 8, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 260, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 721)
[M::mem_pestat] mean and std.dev: (239.00, 131.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 914)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 311, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 919)
[M::mem_pestat] mean and std.dev: (331.84, 161.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1158)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 281, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (276.54, 115.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683594 reads in 193.214 CPU sec, 6.141 real sec
sorting block 50, #reads = 1069254 mem = 536879448 peak = 1054302208
[M::mem_process_seqs] Processed 683832 reads in 128.163 CPU sec, 4.069 real sec
sorting block 51, #reads = 1069297 mem = 536877760 peak = 1063071744
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 277995, 5, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 311, 500)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1018)
[M::mem_pestat] mean and std.dev: (340.43, 190.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1277)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 312, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 920)
[M::mem_pestat] mean and std.dev: (332.47, 160.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1159)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 251, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 621)
[M::mem_pestat] mean and std.dev: (231.72, 92.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 768)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683474 sequences (100000067 bp) in 2.679 CPU sec, 2.818 real sec...
[M::process] read 682840 sequences (100000123 bp) in 1.900 CPU sec, 1.901 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 277953, 5, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 205, 568)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1364)
[M::mem_pestat] mean and std.dev: (349.03, 295.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1762)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 315, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 925)
[M::mem_pestat] mean and std.dev: (335.28, 162.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1165)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 270, 428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 874)
[M::mem_pestat] mean and std.dev: (304.65, 153.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1097)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683632 reads in 192.354 CPU sec, 6.111 real sec
[M::mem_process_seqs] Processed 683266 reads in 126.073 CPU sec, 4.000 real sec
sorting block 52, #reads = 1068858 mem = 536886688 peak = 1063071744
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 278343, 13, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 240, 420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 898)
[M::mem_pestat] mean and std.dev: (278.82, 152.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1137)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 314, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 918)
[M::mem_pestat] mean and std.dev: (333.94, 161.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1156)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (417, 675, 2775)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7491)
[M::mem_pestat] mean and std.dev: (1092.08, 979.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9849)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 346, 544)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1200)
[M::mem_pestat] mean and std.dev: (348.16, 206.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1528)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683206 sequences (100000244 bp) in 2.860 CPU sec, 3.006 real sec...
[M::process] read 683016 sequences (100000236 bp) in 1.840 CPU sec, 1.843 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 277805, 8, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 349, 567)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1315)
[M::mem_pestat] mean and std.dev: (310.11, 221.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1689)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 314, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 913)
[M::mem_pestat] mean and std.dev: (333.16, 159.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1149)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 297, 508)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1146)
[M::mem_pestat] mean and std.dev: (314.31, 149.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1465)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683474 reads in 190.873 CPU sec, 6.060 real sec
[M::mem_process_seqs] Processed 682840 reads in 126.884 CPU sec, 4.036 real sec
sorting block 53, #reads = 1068467 mem = 536878028 peak = 1063071744
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 277895, 13, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 307, 504)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1060)
[M::mem_pestat] mean and std.dev: (345.76, 234.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1338)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 315, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 919)
[M::mem_pestat] mean and std.dev: (334.79, 161.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1157)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (595, 1051, 1105)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2125)
[M::mem_pestat] mean and std.dev: (891.31, 414.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2635)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (294, 423, 518)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 966)
[M::mem_pestat] mean and std.dev: (362.00, 159.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1190)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683084 sequences (100000136 bp) in 2.733 CPU sec, 2.878 real sec...
[M::process] read 682692 sequences (100000266 bp) in 2.040 CPU sec, 2.040 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 278441, 15, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 216, 821)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2179)
[M::mem_pestat] mean and std.dev: (348.55, 343.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2858)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 317, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 938)
[M::mem_pestat] mean and std.dev: (338.26, 164.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1182)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (735, 995, 1498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3024)
[M::mem_pestat] mean and std.dev: (949.57, 619.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3787)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 273, 962)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2446)
[M::mem_pestat] mean and std.dev: (487.03, 413.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3188)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683206 reads in 197.698 CPU sec, 6.286 real sec
sorting block 54, #reads = 1067810 mem = 536883446 peak = 1063071744
[M::mem_process_seqs] Processed 683016 reads in 131.776 CPU sec, 4.182 real sec
sorting block 55, #reads = 1067475 mem = 536882404 peak = 1063071744
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 278189, 14, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 266, 923)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2345)
[M::mem_pestat] mean and std.dev: (459.14, 394.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3056)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 317, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 937)
[M::mem_pestat] mean and std.dev: (337.84, 165.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1181)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (63, 84, 747)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2115)
[M::mem_pestat] mean and std.dev: (402.93, 585.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2799)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 266, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 673)
[M::mem_pestat] mean and std.dev: (291.75, 143.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683138 sequences (100000299 bp) in 2.855 CPU sec, 2.975 real sec...
[M::process] read 682546 sequences (100000002 bp) in 1.466 CPU sec, 1.473 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 278061, 15, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 267, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (294.64, 156.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 938)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 320, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 945)
[M::mem_pestat] mean and std.dev: (341.06, 166.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1191)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (823, 1311, 2222)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5020)
[M::mem_pestat] mean and std.dev: (1257.87, 873.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6419)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 292, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 902)
[M::mem_pestat] mean and std.dev: (351.57, 172.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1128)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683084 reads in 197.039 CPU sec, 6.275 real sec
[M::mem_process_seqs] Processed 682692 reads in 131.355 CPU sec, 4.192 real sec
sorting block 56, #reads = 1066328 mem = 536878706 peak = 1063071744
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 278091, 22, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 309, 559)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1299)
[M::mem_pestat] mean and std.dev: (376.08, 323.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1669)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 317, 451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 943)
[M::mem_pestat] mean and std.dev: (339.41, 166.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1189)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (367, 1065, 3339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9283)
[M::mem_pestat] mean and std.dev: (2050.86, 2163.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12255)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 399, 541)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1159)
[M::mem_pestat] mean and std.dev: (350.06, 182.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1468)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682988 sequences (100000240 bp) in 2.568 CPU sec, 2.672 real sec...
[M::process] read 687520 sequences (100000114 bp) in 1.897 CPU sec, 1.907 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 278725, 11, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 393, 654)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1478)
[M::mem_pestat] mean and std.dev: (397.50, 234.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1890)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 318, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 942)
[M::mem_pestat] mean and std.dev: (341.00, 168.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1187)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 483, 696)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1782)
[M::mem_pestat] mean and std.dev: (433.45, 284.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2325)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 389, 510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1096)
[M::mem_pestat] mean and std.dev: (357.29, 140.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1389)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683138 reads in 188.939 CPU sec, 6.000 real sec
[M::mem_process_seqs] Processed 682546 reads in 124.693 CPU sec, 3.961 real sec
sorting block 57, #reads = 1067071 mem = 536879165 peak = 1063071744
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 278769, 6, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 237, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1053)
[M::mem_pestat] mean and std.dev: (307.61, 192.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1346)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 317, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 946)
[M::mem_pestat] mean and std.dev: (340.09, 167.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1193)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (297, 384, 771)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1719)
[M::mem_pestat] mean and std.dev: (508.39, 332.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2193)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 687226 sequences (100000005 bp) in 2.843 CPU sec, 2.950 real sec...
[M::process] read 686780 sequences (100000193 bp) in 1.845 CPU sec, 1.849 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 279392, 16, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 287, 425)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 843)
[M::mem_pestat] mean and std.dev: (288.90, 130.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1052)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 296, 423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 887)
[M::mem_pestat] mean and std.dev: (317.77, 157.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1119)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (410, 758, 1051)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2333)
[M::mem_pestat] mean and std.dev: (590.31, 362.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2974)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 325, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 929)
[M::mem_pestat] mean and std.dev: (305.11, 151.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1171)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682988 reads in 196.329 CPU sec, 6.234 real sec
[M::mem_process_seqs] Processed 687520 reads in 132.512 CPU sec, 4.212 real sec
sorting block 58, #reads = 1067296 mem = 536886190 peak = 1063071744
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 279503, 18, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 343, 1327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3583)
[M::mem_pestat] mean and std.dev: (753.65, 806.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4711)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 299, 427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 897)
[M::mem_pestat] mean and std.dev: (320.32, 158.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1132)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (113, 498, 1354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3836)
[M::mem_pestat] mean and std.dev: (732.72, 711.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5077)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 286, 524)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1194)
[M::mem_pestat] mean and std.dev: (340.81, 241.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1529)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 686964 sequences (100000042 bp) in 2.513 CPU sec, 2.619 real sec...
[M::process] read 686090 sequences (100000281 bp) in 1.910 CPU sec, 1.909 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 279536, 15, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 416, 702)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1688)
[M::mem_pestat] mean and std.dev: (519.25, 397.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2181)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 300, 428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 898)
[M::mem_pestat] mean and std.dev: (321.56, 158.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1133)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (623, 1753, 4451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12107)
[M::mem_pestat] mean and std.dev: (2035.00, 1663.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 15935)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 418, 810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2000)
[M::mem_pestat] mean and std.dev: (448.62, 339.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2595)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 687226 reads in 186.840 CPU sec, 5.944 real sec
sorting block 59, #reads = 1069142 mem = 536879887 peak = 1063071744
[M::mem_process_seqs] Processed 686780 reads in 122.941 CPU sec, 3.900 real sec
sorting block 60, #reads = 1072827 mem = 536877826 peak = 1063071744
[M::process] read 685840 sequences (100000120 bp) in 2.190 CPU sec, 2.282 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 278895, 11, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 307, 675)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1735)
[M::mem_pestat] mean and std.dev: (373.52, 271.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2265)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 302, 429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 899)
[M::mem_pestat] mean and std.dev: (322.38, 158.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1134)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (996, 4834, 6187)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 16569)
[M::mem_pestat] mean and std.dev: (4221.18, 3144.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 21760)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 233, 505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1195)
[M::mem_pestat] mean and std.dev: (362.14, 278.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1540)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 685992 sequences (100000020 bp) in 1.506 CPU sec, 1.513 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 278818, 9, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 287, 958)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2492)
[M::mem_pestat] mean and std.dev: (539.68, 552.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3259)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 305, 433)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 907)
[M::mem_pestat] mean and std.dev: (325.31, 159.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1144)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 283, 547)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1257)
[M::mem_pestat] mean and std.dev: (318.24, 168.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1612)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 278851, 10, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (283, 388, 565)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1129)
[M::mem_pestat] mean and std.dev: (325.02, 146.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1411)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 305, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 904)
[M::mem_pestat] mean and std.dev: (324.58, 158.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1140)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (901, 3115, 4828)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12682)
[M::mem_pestat] mean and std.dev: (2876.00, 1806.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16609)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 257, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 992)
[M::mem_pestat] mean and std.dev: (332.74, 195.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1255)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 686964 reads in 262.486 CPU sec, 8.398 real sec
[M::mem_process_seqs] Processed 686090 reads in 198.365 CPU sec, 6.362 real sec
[M::mem_process_seqs] Processed 685840 reads in 220.093 CPU sec, 7.085 real sec
sorting block 61, #reads = 1071706 mem = 536878278 peak = 1063071744
[M::process] read 685226 sequences (100000251 bp) in 2.166 CPU sec, 2.292 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 279131, 6, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 282, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1085)
[M::mem_pestat] mean and std.dev: (309.00, 205.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1394)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 306, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 916)
[M::mem_pestat] mean and std.dev: (326.49, 160.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1156)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 323, 565)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1287)
[M::mem_pestat] mean and std.dev: (296.19, 173.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1648)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 62, #reads = 1072486 mem = 536877840 peak = 1063071744
[M::process] read 684730 sequences (100000244 bp) in 2.063 CPU sec, 2.212 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 278281, 15, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 304, 588)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1370)
[M::mem_pestat] mean and std.dev: (367.49, 233.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1761)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 309, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 919)
[M::mem_pestat] mean and std.dev: (329.39, 160.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1159)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (374, 515, 1071)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2465)
[M::mem_pestat] mean and std.dev: (528.64, 368.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3162)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (313, 415, 1522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3940)
[M::mem_pestat] mean and std.dev: (726.86, 588.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5149)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 684650 sequences (100000248 bp) in 1.440 CPU sec, 1.437 real sec...
[M::mem_process_seqs] Processed 685992 reads in 191.408 CPU sec, 6.113 real sec
[M::mem_process_seqs] Processed 685226 reads in 135.669 CPU sec, 4.313 real sec
sorting block 63, #reads = 1071481 mem = 536882800 peak = 1063071744
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 279191, 10, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 291, 553)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1283)
[M::mem_pestat] mean and std.dev: (362.00, 250.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1648)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 312, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 924)
[M::mem_pestat] mean and std.dev: (332.05, 161.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1165)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (25, 753, 932)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2746)
[M::mem_pestat] mean and std.dev: (637.89, 729.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3653)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 328, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 932)
[M::mem_pestat] mean and std.dev: (322.86, 146.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1170)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 684574 sequences (100000205 bp) in 2.361 CPU sec, 2.502 real sec...
[M::process] read 684290 sequences (100000206 bp) in 1.840 CPU sec, 1.847 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 278332, 9, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 343, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 961)
[M::mem_pestat] mean and std.dev: (317.18, 182.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1213)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 312, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 921)
[M::mem_pestat] mean and std.dev: (331.30, 160.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1161)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 298, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 923)
[M::mem_pestat] mean and std.dev: (332.20, 157.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1157)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684730 reads in 184.265 CPU sec, 5.856 real sec
[M::mem_process_seqs] Processed 684650 reads in 130.098 CPU sec, 4.149 real sec
sorting block 64, #reads = 1071082 mem = 536879640 peak = 1063071744
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 278211, 7, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 217, 614)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1560)
[M::mem_pestat] mean and std.dev: (204.09, 105.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2033)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 312, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 916)
[M::mem_pestat] mean and std.dev: (331.36, 160.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1154)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 252, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 776)
[M::mem_pestat] mean and std.dev: (281.17, 159.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 978)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683924 sequences (100000267 bp) in 2.522 CPU sec, 2.664 real sec...
[M::process] read 684220 sequences (100000058 bp) in 1.880 CPU sec, 1.883 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 278503, 15, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 255, 382)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 788)
[M::mem_pestat] mean and std.dev: (271.13, 125.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 991)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 314, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 928)
[M::mem_pestat] mean and std.dev: (333.54, 161.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1170)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (484, 1542, 1716)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4180)
[M::mem_pestat] mean and std.dev: (1200.53, 921.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5412)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 364, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 723)
[M::mem_pestat] mean and std.dev: (344.49, 140.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 905)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684574 reads in 182.442 CPU sec, 5.804 real sec
sorting block 65, #reads = 1070059 mem = 536879795 peak = 1063071744
[M::mem_process_seqs] Processed 684290 reads in 121.421 CPU sec, 3.929 real sec
sorting block 66, #reads = 1070351 mem = 536879972 peak = 1063071744
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 277945, 15, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 350, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1027)
[M::mem_pestat] mean and std.dev: (338.82, 187.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1314)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 314, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 926)
[M::mem_pestat] mean and std.dev: (333.45, 161.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1167)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (252, 674, 2501)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6999)
[M::mem_pestat] mean and std.dev: (1532.27, 1778.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9248)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (263, 377, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 845)
[M::mem_pestat] mean and std.dev: (349.26, 131.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1039)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 684368 sequences (100000027 bp) in 2.550 CPU sec, 2.672 real sec...
[M::process] read 685678 sequences (100000031 bp) in 1.890 CPU sec, 1.884 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 278172, 19, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 281, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 820)
[M::mem_pestat] mean and std.dev: (337.98, 172.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1026)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 314, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 926)
[M::mem_pestat] mean and std.dev: (333.29, 161.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1167)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 788, 3738)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10938)
[M::mem_pestat] mean and std.dev: (1656.42, 1827.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14538)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 239, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (235.94, 94.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 882)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683924 reads in 189.104 CPU sec, 6.074 real sec
[M::mem_process_seqs] Processed 684220 reads in 125.170 CPU sec, 3.980 real sec
sorting block 67, #reads = 1069437 mem = 536881962 peak = 1063071744
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 278041, 16, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 381, 907)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2281)
[M::mem_pestat] mean and std.dev: (548.24, 465.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2968)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 313, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 933)
[M::mem_pestat] mean and std.dev: (333.32, 162.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1177)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (316, 797, 797)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1759)
[M::mem_pestat] mean and std.dev: (610.47, 425.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2311)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (283, 330, 583)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1183)
[M::mem_pestat] mean and std.dev: (395.36, 248.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1483)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 685138 sequences (100000209 bp) in 2.561 CPU sec, 2.656 real sec...
[M::process] read 684464 sequences (100000143 bp) in 1.890 CPU sec, 1.892 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 279046, 5, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 253, 485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1063)
[M::mem_pestat] mean and std.dev: (299.55, 160.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1352)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 300, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 906)
[M::mem_pestat] mean and std.dev: (324.19, 160.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1143)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 311, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 827)
[M::mem_pestat] mean and std.dev: (303.66, 135.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1018)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684368 reads in 186.873 CPU sec, 5.935 real sec
[M::mem_process_seqs] Processed 685678 reads in 124.232 CPU sec, 3.934 real sec
sorting block 68, #reads = 1067901 mem = 536877646 peak = 1063071744
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 278956, 23, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 241, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 637)
[M::mem_pestat] mean and std.dev: (217.71, 72.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 799)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 303, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 896)
[M::mem_pestat] mean and std.dev: (324.12, 158.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1129)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (324, 715, 2274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6174)
[M::mem_pestat] mean and std.dev: (779.05, 768.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8124)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 330, 393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 723)
[M::mem_pestat] mean and std.dev: (281.56, 114.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 888)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 684500 sequences (100000296 bp) in 2.448 CPU sec, 2.543 real sec...
[M::process] read 684328 sequences (100000089 bp) in 1.889 CPU sec, 1.894 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 278419, 11, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 247, 613)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1549)
[M::mem_pestat] mean and std.dev: (323.21, 241.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2017)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 306, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 907)
[M::mem_pestat] mean and std.dev: (327.20, 158.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1143)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (444, 830, 1445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3447)
[M::mem_pestat] mean and std.dev: (1009.91, 832.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4448)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 298, 567)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1207)
[M::mem_pestat] mean and std.dev: (346.76, 177.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1527)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 685138 reads in 186.323 CPU sec, 5.917 real sec
sorting block 69, #reads = 1069302 mem = 536882822 peak = 1063071744
[M::mem_process_seqs] Processed 684464 reads in 123.260 CPU sec, 3.912 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 277900, 4, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 215, 397)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 873)
[M::mem_pestat] mean and std.dev: (250.33, 158.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1111)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 306, 433)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 899)
[M::mem_pestat] mean and std.dev: (326.86, 157.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1132)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 421, 933)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2445)
[M::mem_pestat] mean and std.dev: (406.54, 322.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3201)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683832 sequences (100000131 bp) in 2.659 CPU sec, 2.785 real sec...
[M::process] read 684066 sequences (100000219 bp) in 1.860 CPU sec, 1.854 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 278157, 8, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 287, 552)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1276)
[M::mem_pestat] mean and std.dev: (348.93, 240.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1638)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 307, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 896)
[M::mem_pestat] mean and std.dev: (326.07, 156.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1128)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 349, 730)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1718)
[M::mem_pestat] mean and std.dev: (378.19, 273.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2212)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684500 reads in 191.603 CPU sec, 6.322 real sec
sorting block 70, #reads = 1068020 mem = 536879270 peak = 1063071744
[M::mem_process_seqs] Processed 684328 reads in 122.022 CPU sec, 3.879 real sec
sorting block 71, #reads = 1068372 mem = 536880903 peak = 1063071744
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 278154, 14, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 329, 545)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1189)
[M::mem_pestat] mean and std.dev: (357.16, 209.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1511)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 308, 433)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 897)
[M::mem_pestat] mean and std.dev: (327.26, 156.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1129)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 541, 917)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2271)
[M::mem_pestat] mean and std.dev: (468.08, 319.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2948)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 537, 748)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1748)
[M::mem_pestat] mean and std.dev: (496.94, 328.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2248)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683602 sequences (100000296 bp) in 2.542 CPU sec, 2.664 real sec...
[M::process] read 683648 sequences (100000160 bp) in 1.880 CPU sec, 1.875 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 278488, 10, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 336, 538)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1236)
[M::mem_pestat] mean and std.dev: (326.45, 174.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1585)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 308, 434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 900)
[M::mem_pestat] mean and std.dev: (327.54, 157.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1133)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (482, 1222, 3023)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8105)
[M::mem_pestat] mean and std.dev: (1775.30, 1583.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10646)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 333, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 854)
[M::mem_pestat] mean and std.dev: (337.27, 173.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1054)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683832 reads in 185.922 CPU sec, 5.906 real sec
[M::mem_process_seqs] Processed 684066 reads in 121.362 CPU sec, 3.852 real sec
sorting block 72, #reads = 1068238 mem = 536883255 peak = 1063071744
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 278063, 21, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 315, 836)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2130)
[M::mem_pestat] mean and std.dev: (317.97, 203.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2777)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 307, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 892)
[M::mem_pestat] mean and std.dev: (326.85, 156.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1122)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 737, 937)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2395)
[M::mem_pestat] mean and std.dev: (744.52, 615.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3208)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 340, 513)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1153)
[M::mem_pestat] mean and std.dev: (349.29, 167.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1473)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683354 sequences (100000105 bp) in 2.848 CPU sec, 2.948 real sec...
[M::process] read 683110 sequences (100000223 bp) in 1.870 CPU sec, 1.876 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 277797, 14, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 420, 988)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2434)
[M::mem_pestat] mean and std.dev: (581.40, 411.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3157)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 308, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 886)
[M::mem_pestat] mean and std.dev: (326.15, 155.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1114)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (297, 534, 769)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1713)
[M::mem_pestat] mean and std.dev: (482.54, 294.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2185)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 357, 597)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1347)
[M::mem_pestat] mean and std.dev: (435.02, 280.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1722)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683602 reads in 187.945 CPU sec, 5.965 real sec
[M::mem_process_seqs] Processed 683648 reads in 124.500 CPU sec, 3.953 real sec
sorting block 73, #reads = 1067819 mem = 536880033 peak = 1063071744
[M::process] read 683280 sequences (100000163 bp) in 2.597 CPU sec, 2.752 real sec...
[M::process] read 682990 sequences (100000209 bp) in 1.810 CPU sec, 1.806 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 278273, 30, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 307, 597)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1461)
[M::mem_pestat] mean and std.dev: (344.16, 249.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1893)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 313, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 915)
[M::mem_pestat] mean and std.dev: (332.73, 160.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1152)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (403, 3612, 4047)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11335)
[M::mem_pestat] mean and std.dev: (2609.97, 2191.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14979)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 310, 582)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1298)
[M::mem_pestat] mean and std.dev: (389.49, 275.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1656)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683110 reads in 106.065 CPU sec, 3.357 real sec
sorting block 74, #reads = 1066068 mem = 536879247 peak = 1063071744
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 278206, 9, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 255, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1042)
[M::mem_pestat] mean and std.dev: (301.92, 181.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1330)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 310, 434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 894)
[M::mem_pestat] mean and std.dev: (328.81, 156.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1124)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 460, 786)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1896)
[M::mem_pestat] mean and std.dev: (511.02, 373.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2451)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 278017, 12, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 332, 767)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1931)
[M::mem_pestat] mean and std.dev: (448.39, 418.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2513)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 314, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 924)
[M::mem_pestat] mean and std.dev: (334.48, 161.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1164)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (318, 2522, 4460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12744)
[M::mem_pestat] mean and std.dev: (2425.67, 2387.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16886)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 509, 1268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3304)
[M::mem_pestat] mean and std.dev: (804.42, 863.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4322)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682848 sequences (100000135 bp) in 2.059 CPU sec, 2.068 real sec...
[M::mem_process_seqs] Processed 683354 reads in 286.584 CPU sec, 9.115 real sec
[M::mem_process_seqs] Processed 683280 reads in 144.305 CPU sec, 4.608 real sec
sorting block 75, #reads = 1067353 mem = 536878683 peak = 1063071744
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 278280, 21, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 391, 582)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1430)
[M::mem_pestat] mean and std.dev: (303.76, 160.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1854)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 315, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 925)
[M::mem_pestat] mean and std.dev: (335.89, 163.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1165)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (374, 971, 1712)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4388)
[M::mem_pestat] mean and std.dev: (885.78, 586.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5726)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 302, 528)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1110)
[M::mem_pestat] mean and std.dev: (372.21, 216.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1401)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682474 sequences (100000044 bp) in 2.566 CPU sec, 2.700 real sec...
[M::process] read 691192 sequences (100000226 bp) in 1.920 CPU sec, 1.921 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 277943, 12, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 368, 543)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1301)
[M::mem_pestat] mean and std.dev: (334.32, 215.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1680)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 317, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 935)
[M::mem_pestat] mean and std.dev: (338.13, 164.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1178)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (110, 407, 530)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1370)
[M::mem_pestat] mean and std.dev: (258.30, 213.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1790)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (284, 382, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 815)
[M::mem_pestat] mean and std.dev: (339.86, 115.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 992)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682990 reads in 184.196 CPU sec, 5.847 real sec
sorting block 76, #reads = 1067181 mem = 536884904 peak = 1063071744
[M::mem_process_seqs] Processed 682848 reads in 123.530 CPU sec, 3.919 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 278039, 5, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 250, 518)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1190)
[M::mem_pestat] mean and std.dev: (283.39, 167.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1526)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 320, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 945)
[M::mem_pestat] mean and std.dev: (341.25, 166.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1191)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 388, 649)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1461)
[M::mem_pestat] mean and std.dev: (460.83, 319.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1867)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 690910 sequences (100000221 bp) in 2.697 CPU sec, 2.858 real sec...
[M::process] read 689300 sequences (100000015 bp) in 1.925 CPU sec, 1.930 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 281189, 16, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 252, 722)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1820)
[M::mem_pestat] mean and std.dev: (352.87, 249.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2369)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 272, 400)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 844)
[M::mem_pestat] mean and std.dev: (301.49, 154.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1066)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (486, 879, 1568)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3732)
[M::mem_pestat] mean and std.dev: (747.08, 450.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4814)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 303, 495)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1027)
[M::mem_pestat] mean and std.dev: (338.83, 191.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1293)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682474 reads in 190.053 CPU sec, 6.023 real sec
sorting block 77, #reads = 1066306 mem = 536878977 peak = 1063071744
[M::mem_process_seqs] Processed 691192 reads in 131.235 CPU sec, 4.168 real sec
sorting block 78, #reads = 1066247 mem = 536883609 peak = 1063071744
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 281300, 7, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 282, 538)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1314)
[M::mem_pestat] mean and std.dev: (329.00, 215.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1702)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 274, 404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 854)
[M::mem_pestat] mean and std.dev: (303.34, 155.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1079)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (282, 482, 570)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1146)
[M::mem_pestat] mean and std.dev: (416.70, 213.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1434)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 687466 sequences (100000244 bp) in 2.714 CPU sec, 2.861 real sec...
[M::process] read 686760 sequences (100000032 bp) in 1.700 CPU sec, 1.700 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 281183, 6, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 212, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (235.85, 144.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 968)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 283, 417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 883)
[M::mem_pestat] mean and std.dev: (311.67, 159.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1116)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 330, 483)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 983)
[M::mem_pestat] mean and std.dev: (372.57, 196.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1233)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 690910 reads in 191.018 CPU sec, 6.078 real sec
[M::mem_process_seqs] Processed 689300 reads in 123.826 CPU sec, 3.932 real sec
sorting block 79, #reads = 1070219 mem = 536880147 peak = 1063071744
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 280668, 12, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 272, 427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 911)
[M::mem_pestat] mean and std.dev: (294.38, 134.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1153)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 294, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 910)
[M::mem_pestat] mean and std.dev: (321.02, 163.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1150)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (325, 673, 958)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2224)
[M::mem_pestat] mean and std.dev: (683.82, 557.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2913)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 418, 649)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1471)
[M::mem_pestat] mean and std.dev: (399.69, 238.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1882)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 686366 sequences (100000216 bp) in 2.717 CPU sec, 2.827 real sec...
[M::process] read 686114 sequences (100000241 bp) in 1.480 CPU sec, 1.473 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 280766, 5, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 396, 428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 958)
[M::mem_pestat] mean and std.dev: (336.05, 168.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1223)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 297, 434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 920)
[M::mem_pestat] mean and std.dev: (324.10, 164.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1163)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 272, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 713)
[M::mem_pestat] mean and std.dev: (258.76, 89.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 888)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 687466 reads in 182.186 CPU sec, 5.793 real sec
[M::mem_process_seqs] Processed 686760 reads in 118.765 CPU sec, 3.781 real sec
sorting block 80, #reads = 1070731 mem = 536877971 peak = 1063071744
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 280373, 15, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (282, 455, 542)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1062)
[M::mem_pestat] mean and std.dev: (385.44, 163.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1322)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 300, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 925)
[M::mem_pestat] mean and std.dev: (326.06, 164.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1169)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 1284, 4339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12577)
[M::mem_pestat] mean and std.dev: (1707.93, 1669.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16696)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 383, 726)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1700)
[M::mem_pestat] mean and std.dev: (514.67, 409.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2187)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 685492 sequences (100000019 bp) in 2.387 CPU sec, 2.483 real sec...
[M::process] read 685566 sequences (100000181 bp) in 1.850 CPU sec, 1.852 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 279944, 10, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (296, 410, 949)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2255)
[M::mem_pestat] mean and std.dev: (563.43, 421.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2908)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 302, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 929)
[M::mem_pestat] mean and std.dev: (327.41, 164.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1174)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 435, 1239)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3271)
[M::mem_pestat] mean and std.dev: (850.00, 877.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4362)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 296, 542)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1128)
[M::mem_pestat] mean and std.dev: (330.42, 129.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1421)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 686366 reads in 182.352 CPU sec, 5.793 real sec
sorting block 81, #reads = 1071598 mem = 536878167 peak = 1063071744
[M::mem_process_seqs] Processed 686114 reads in 121.257 CPU sec, 3.850 real sec
sorting block 82, #reads = 1070229 mem = 536875622 peak = 1063071744
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 279498, 8, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 236, 399)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 825)
[M::mem_pestat] mean and std.dev: (276.08, 155.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1038)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 304, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 928)
[M::mem_pestat] mean and std.dev: (328.80, 164.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1172)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 416, 416)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 838)
[M::mem_pestat] mean and std.dev: (324.33, 148.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1049)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 685180 sequences (100000280 bp) in 2.700 CPU sec, 2.840 real sec...
[M::process] read 684874 sequences (100000179 bp) in 1.890 CPU sec, 1.891 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 279479, 15, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 258, 391)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 867)
[M::mem_pestat] mean and std.dev: (280.05, 171.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1105)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 305, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 934)
[M::mem_pestat] mean and std.dev: (329.71, 164.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1180)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (464, 899, 6141)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 17495)
[M::mem_pestat] mean and std.dev: (2579.40, 2934.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 23172)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 292, 670)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1684)
[M::mem_pestat] mean and std.dev: (382.43, 241.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2191)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 685492 reads in 186.737 CPU sec, 5.932 real sec
[M::mem_process_seqs] Processed 685566 reads in 132.106 CPU sec, 4.225 real sec
sorting block 83, #reads = 1068788 mem = 536880281 peak = 1063071744
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 279302, 5, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 335, 510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1172)
[M::mem_pestat] mean and std.dev: (356.54, 265.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1503)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 308, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 938)
[M::mem_pestat] mean and std.dev: (331.62, 165.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1185)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 437, 735)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1765)
[M::mem_pestat] mean and std.dev: (411.26, 308.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2280)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 684680 sequences (100000298 bp) in 2.676 CPU sec, 2.826 real sec...
[M::process] read 684612 sequences (100000164 bp) in 1.890 CPU sec, 1.888 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 278833, 8, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 288, 385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 733)
[M::mem_pestat] mean and std.dev: (269.32, 120.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 907)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 308, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 936)
[M::mem_pestat] mean and std.dev: (331.65, 164.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1182)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 369, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 858)
[M::mem_pestat] mean and std.dev: (331.62, 141.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1067)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 685180 reads in 190.965 CPU sec, 6.069 real sec
[M::mem_process_seqs] Processed 684874 reads in 127.357 CPU sec, 4.043 real sec
sorting block 84, #reads = 1069091 mem = 536879818 peak = 1063071744
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 279290, 12, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 241, 493)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1187)
[M::mem_pestat] mean and std.dev: (270.34, 213.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1534)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 310, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 934)
[M::mem_pestat] mean and std.dev: (332.53, 164.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1179)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1077, 2574, 2703)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5955)
[M::mem_pestat] mean and std.dev: (1666.70, 845.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7581)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 260, 406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 890)
[M::mem_pestat] mean and std.dev: (304.28, 170.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1132)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 684552 sequences (100000277 bp) in 2.771 CPU sec, 2.873 real sec...
[M::process] read 684306 sequences (100000041 bp) in 1.900 CPU sec, 1.901 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 278540, 6, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 348, 682)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1628)
[M::mem_pestat] mean and std.dev: (487.53, 381.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2101)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 310, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 929)
[M::mem_pestat] mean and std.dev: (332.03, 163.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1172)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (319, 486, 855)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1927)
[M::mem_pestat] mean and std.dev: (479.24, 384.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2463)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684680 reads in 197.155 CPU sec, 6.256 real sec
sorting block 85, #reads = 1067399 mem = 536880882 peak = 1063071744
[M::mem_process_seqs] Processed 684612 reads in 131.517 CPU sec, 4.181 real sec
sorting block 86, #reads = 1066027 mem = 536879610 peak = 1063071744
[M::process] read 683936 sequences (100000007 bp) in 2.326 CPU sec, 2.426 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 279028, 9, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 392, 1262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3468)
[M::mem_pestat] mean and std.dev: (541.15, 458.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4571)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 310, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 932)
[M::mem_pestat] mean and std.dev: (332.48, 163.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1176)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 297, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 882)
[M::mem_pestat] mean and std.dev: (271.00, 101.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1102)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 684098 sequences (100000155 bp) in 1.570 CPU sec, 1.573 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 278901, 17, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 298, 596)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1448)
[M::mem_pestat] mean and std.dev: (385.00, 298.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1874)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 311, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 927)
[M::mem_pestat] mean and std.dev: (333.00, 163.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1169)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1374, 1595, 2809)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5679)
[M::mem_pestat] mean and std.dev: (1909.12, 1463.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7765)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 340, 592)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1306)
[M::mem_pestat] mean and std.dev: (391.55, 219.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1663)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 279012, 14, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 493, 1717)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4687)
[M::mem_pestat] mean and std.dev: (894.63, 912.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6172)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 312, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 934)
[M::mem_pestat] mean and std.dev: (334.30, 164.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1178)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (132, 1208, 1579)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4473)
[M::mem_pestat] mean and std.dev: (1238.79, 1235.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6181)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 343, 486)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1072)
[M::mem_pestat] mean and std.dev: (339.81, 172.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1365)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684552 reads in 275.739 CPU sec, 9.063 real sec
[M::mem_process_seqs] Processed 684306 reads in 206.889 CPU sec, 6.633 real sec
[M::mem_process_seqs] Processed 683936 reads in 229.130 CPU sec, 7.364 real sec
sorting block 87, #reads = 1066126 mem = 536884030 peak = 1063071744
[M::process] read 684202 sequences (100000044 bp) in 2.956 CPU sec, 3.127 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 278817, 8, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 336, 537)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1189)
[M::mem_pestat] mean and std.dev: (348.09, 221.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1515)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 311, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 933)
[M::mem_pestat] mean and std.dev: (333.45, 163.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1177)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 250, 581)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1367)
[M::mem_pestat] mean and std.dev: (408.59, 317.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1760)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683916 sequences (100000079 bp) in 2.088 CPU sec, 2.174 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 278357, 12, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 337, 588)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1348)
[M::mem_pestat] mean and std.dev: (362.52, 230.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1728)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 310, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 927)
[M::mem_pestat] mean and std.dev: (331.98, 162.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1169)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 716, 2971)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8449)
[M::mem_pestat] mean and std.dev: (1367.25, 1560.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11188)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (279, 379, 548)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1086)
[M::mem_pestat] mean and std.dev: (387.82, 198.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1355)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683620 sequences (100000228 bp) in 1.420 CPU sec, 1.416 real sec...
[M::mem_process_seqs] Processed 684098 reads in 202.482 CPU sec, 6.447 real sec
sorting block 88, #reads = 1066434 mem = 536881577 peak = 1063071744
[M::mem_process_seqs] Processed 684202 reads in 135.748 CPU sec, 4.297 real sec
sorting block 89, #reads = 1065981 mem = 536880315 peak = 1127305216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 278554, 13, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 366, 790)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1934)
[M::mem_pestat] mean and std.dev: (432.79, 266.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2506)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 311, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 925)
[M::mem_pestat] mean and std.dev: (332.77, 162.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1166)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (112, 945, 1608)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4600)
[M::mem_pestat] mean and std.dev: (1133.38, 1126.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6096)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 275, 504)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1142)
[M::mem_pestat] mean and std.dev: (287.36, 175.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1461)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683650 sequences (100000241 bp) in 2.812 CPU sec, 2.951 real sec...
[M::process] read 683780 sequences (100000186 bp) in 1.510 CPU sec, 1.507 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 278538, 13, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 258, 416)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 840)
[M::mem_pestat] mean and std.dev: (288.52, 130.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1052)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 312, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 928)
[M::mem_pestat] mean and std.dev: (333.39, 162.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1170)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 901, 1920)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5380)
[M::mem_pestat] mean and std.dev: (804.92, 739.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7110)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 213, 410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 878)
[M::mem_pestat] mean and std.dev: (253.39, 124.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1112)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683916 reads in 201.843 CPU sec, 6.418 real sec
[M::mem_process_seqs] Processed 683620 reads in 143.562 CPU sec, 4.597 real sec
sorting block 90, #reads = 1064786 mem = 536878933 peak = 1127305216
[M::process] read 683614 sequences (100000015 bp) in 2.287 CPU sec, 2.393 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 277930, 5, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (261, 387, 753)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1737)
[M::mem_pestat] mean and std.dev: (543.98, 430.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2265)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 311, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 928)
[M::mem_pestat] mean and std.dev: (332.94, 162.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1170)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (271, 350, 557)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1129)
[M::mem_pestat] mean and std.dev: (335.30, 160.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1415)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683428 sequences (100000123 bp) in 1.440 CPU sec, 1.440 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 278406, 7, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 224, 298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 572)
[M::mem_pestat] mean and std.dev: (219.13, 80.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 709)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 310, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 919)
[M::mem_pestat] mean and std.dev: (331.60, 161.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1158)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (261, 401, 486)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 936)
[M::mem_pestat] mean and std.dev: (346.15, 148.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1161)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683650 reads in 195.271 CPU sec, 6.225 real sec
sorting block 91, #reads = 1065432 mem = 536880086 peak = 1127305216
[M::mem_process_seqs] Processed 683780 reads in 136.343 CPU sec, 4.370 real sec
[M::process] read 683266 sequences (100000118 bp) in 2.092 CPU sec, 2.200 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 278546, 22, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 289, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 940)
[M::mem_pestat] mean and std.dev: (357.95, 214.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1217)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 311, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 923)
[M::mem_pestat] mean and std.dev: (333.13, 162.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1163)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (323, 366, 858)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1928)
[M::mem_pestat] mean and std.dev: (558.25, 449.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2463)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 329, 599)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1381)
[M::mem_pestat] mean and std.dev: (323.61, 181.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1772)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683516 sequences (100000188 bp) in 1.477 CPU sec, 1.479 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 278485, 13, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 217, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (253.50, 114.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 942)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 313, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 926)
[M::mem_pestat] mean and std.dev: (334.03, 162.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1167)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (347, 365, 1609)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4133)
[M::mem_pestat] mean and std.dev: (921.46, 1044.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5395)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 425, 632)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1478)
[M::mem_pestat] mean and std.dev: (382.17, 288.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1901)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 278303, 11, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 564, 1139)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3019)
[M::mem_pestat] mean and std.dev: (711.00, 594.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3959)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 313, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 929)
[M::mem_pestat] mean and std.dev: (334.66, 162.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1171)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (985, 985, 1488)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2494)
[M::mem_pestat] mean and std.dev: (1045.33, 371.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2997)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 295, 510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1144)
[M::mem_pestat] mean and std.dev: (302.70, 144.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1461)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683614 reads in 278.968 CPU sec, 8.937 real sec
sorting block 92, #reads = 1063946 mem = 536877587 peak = 1127305216
[M::mem_process_seqs] Processed 683428 reads in 211.552 CPU sec, 6.797 real sec
[M::mem_process_seqs] Processed 683266 reads in 233.535 CPU sec, 7.522 real sec
sorting block 93, #reads = 1065352 mem = 536885960 peak = 1127305216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 278749, 17, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 234, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 996)
[M::mem_pestat] mean and std.dev: (275.75, 197.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1265)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 312, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 931)
[M::mem_pestat] mean and std.dev: (334.39, 163.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1174)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (334, 837, 1757)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4603)
[M::mem_pestat] mean and std.dev: (918.73, 738.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6026)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (259, 308, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 892)
[M::mem_pestat] mean and std.dev: (331.37, 183.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1103)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683170 sequences (100000279 bp) in 3.284 CPU sec, 3.490 real sec...
[M::mem_process_seqs] Processed 683516 reads in 110.286 CPU sec, 3.617 real sec
sorting block 94, #reads = 1065769 mem = 536877454 peak = 1127305216
[M::process] read 682816 sequences (100000280 bp) in 2.649 CPU sec, 2.866 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 278587, 11, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 316, 514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1124)
[M::mem_pestat] mean and std.dev: (318.68, 154.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1429)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 315, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 939)
[M::mem_pestat] mean and std.dev: (337.93, 165.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1184)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (539, 629, 1041)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2045)
[M::mem_pestat] mean and std.dev: (623.30, 471.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2547)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (294, 417, 774)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1734)
[M::mem_pestat] mean and std.dev: (442.77, 298.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2214)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683412 sequences (100000296 bp) in 1.924 CPU sec, 1.940 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 278109, 18, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 284, 650)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1610)
[M::mem_pestat] mean and std.dev: (362.64, 294.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2090)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 318, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 944)
[M::mem_pestat] mean and std.dev: (340.25, 166.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1190)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (99, 399, 2260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6582)
[M::mem_pestat] mean and std.dev: (1137.61, 1376.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8743)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (287, 461, 614)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1268)
[M::mem_pestat] mean and std.dev: (483.41, 267.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1595)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 692820 sequences (100000137 bp) in 1.910 CPU sec, 1.912 real sec...
[M::mem_process_seqs] Processed 683170 reads in 199.590 CPU sec, 6.314 real sec
[M::mem_process_seqs] Processed 682816 reads in 136.092 CPU sec, 4.295 real sec
sorting block 95, #reads = 1064039 mem = 536880861 peak = 1127305216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 278382, 15, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 253, 517)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1173)
[M::mem_pestat] mean and std.dev: (340.00, 226.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1501)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 316, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 948)
[M::mem_pestat] mean and std.dev: (339.15, 167.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1196)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 282, 869)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2339)
[M::mem_pestat] mean and std.dev: (431.57, 407.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3074)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 354, 867)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2121)
[M::mem_pestat] mean and std.dev: (461.81, 305.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2748)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693378 sequences (100000278 bp) in 2.380 CPU sec, 2.570 real sec...
[M::process] read 693240 sequences (100000292 bp) in 1.920 CPU sec, 1.922 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 281943, 11, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 240, 865)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2219)
[M::mem_pestat] mean and std.dev: (545.52, 595.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2929)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 264, 388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 816)
[M::mem_pestat] mean and std.dev: (292.56, 149.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1030)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (349, 531, 566)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1000)
[M::mem_pestat] mean and std.dev: (410.78, 162.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1217)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 326, 487)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1027)
[M::mem_pestat] mean and std.dev: (288.64, 107.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1297)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683412 reads in 202.987 CPU sec, 6.457 real sec
sorting block 96, #reads = 1064016 mem = 536882566 peak = 1127305216
[M::mem_process_seqs] Processed 692820 reads in 135.279 CPU sec, 4.308 real sec
sorting block 97, #reads = 1065145 mem = 536880471 peak = 1127305216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 282705, 6, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 181, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 734)
[M::mem_pestat] mean and std.dev: (211.04, 94.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 931)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 262, 386)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 812)
[M::mem_pestat] mean and std.dev: (290.77, 147.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1025)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 338, 530)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1124)
[M::mem_pestat] mean and std.dev: (344.68, 160.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1421)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 691714 sequences (100000016 bp) in 2.911 CPU sec, 3.045 real sec...
[M::process] read 690320 sequences (100000230 bp) in 1.940 CPU sec, 1.942 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 282366, 9, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 276, 480)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1108)
[M::mem_pestat] mean and std.dev: (299.97, 141.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1422)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 263, 385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 809)
[M::mem_pestat] mean and std.dev: (290.12, 146.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1021)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 339, 551)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1339)
[M::mem_pestat] mean and std.dev: (320.74, 208.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1733)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 693378 reads in 207.564 CPU sec, 6.585 real sec
[M::mem_process_seqs] Processed 693240 reads in 138.167 CPU sec, 4.404 real sec
sorting block 98, #reads = 1066751 mem = 536877256 peak = 1127305216
[M::process] read 689340 sequences (100000215 bp) in 2.618 CPU sec, 2.770 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 282322, 16, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 343, 639)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1527)
[M::mem_pestat] mean and std.dev: (382.74, 319.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1971)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 270, 395)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 831)
[M::mem_pestat] mean and std.dev: (296.28, 148.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1049)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (625, 1222, 2117)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5101)
[M::mem_pestat] mean and std.dev: (1199.93, 1063.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6593)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 318, 628)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1460)
[M::mem_pestat] mean and std.dev: (444.97, 327.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1876)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 689706 sequences (100000273 bp) in 1.948 CPU sec, 1.948 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 282633, 15, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (254, 490, 909)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2219)
[M::mem_pestat] mean and std.dev: (596.24, 481.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2874)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 277, 405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 853)
[M::mem_pestat] mean and std.dev: (303.02, 151.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1077)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (446, 631, 674)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1130)
[M::mem_pestat] mean and std.dev: (533.31, 176.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1358)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 421, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 968)
[M::mem_pestat] mean and std.dev: (335.21, 135.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1217)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 691714 reads in 214.084 CPU sec, 7.082 real sec
sorting block 99, #reads = 1065835 mem = 536879139 peak = 1127305216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281396, 8, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 381, 610)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1380)
[M::mem_pestat] mean and std.dev: (433.02, 267.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1765)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 280, 408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 858)
[M::mem_pestat] mean and std.dev: (305.76, 152.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1083)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 280, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 686)
[M::mem_pestat] mean and std.dev: (251.81, 101.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 856)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 688654 sequences (100000209 bp) in 2.258 CPU sec, 2.259 real sec...
[M::mem_process_seqs] Processed 690320 reads in 229.436 CPU sec, 7.277 real sec
[M::mem_process_seqs] Processed 689340 reads in 252.665 CPU sec, 8.287 real sec
sorting block 100, #reads = 1066701 mem = 536881861 peak = 1127305216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 281838, 6, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 269, 566)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1354)
[M::mem_pestat] mean and std.dev: (324.29, 228.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1748)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 281, 411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 867)
[M::mem_pestat] mean and std.dev: (306.95, 154.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1095)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 323, 488)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1112)
[M::mem_pestat] mean and std.dev: (347.07, 267.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1424)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 688056 sequences (100000297 bp) in 2.865 CPU sec, 3.066 real sec...
[M::process] read 688212 sequences (100000008 bp) in 2.040 CPU sec, 2.043 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 281200, 5, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 204, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (215.30, 73.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 845)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 288, 418)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 882)
[M::mem_pestat] mean and std.dev: (312.37, 155.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1114)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (315, 434, 495)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 855)
[M::mem_pestat] mean and std.dev: (377.46, 129.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1035)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 689706 reads in 209.326 CPU sec, 6.896 real sec
[M::mem_process_seqs] Processed 688654 reads in 135.147 CPU sec, 4.309 real sec
sorting block 101, #reads = 1065872 mem = 536884382 peak = 1127305216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 281062, 8, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 352, 542)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1214)
[M::mem_pestat] mean and std.dev: (351.65, 194.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1550)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 290, 421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 887)
[M::mem_pestat] mean and std.dev: (314.82, 156.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1120)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 284, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 644)
[M::mem_pestat] mean and std.dev: (292.52, 109.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 785)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 687780 sequences (100000061 bp) in 2.911 CPU sec, 3.088 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 281298, 13, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 354, 515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1263)
[M::mem_pestat] mean and std.dev: (302.88, 210.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1637)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 686942 sequences (100000214 bp) in 2.140 CPU sec, 2.137 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (187, 289, 421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 889)
[M::mem_pestat] mean and std.dev: (314.09, 156.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1123)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (56, 726, 1924)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5660)
[M::mem_pestat] mean and std.dev: (1200.23, 1467.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7528)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (323, 509, 668)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1358)
[M::mem_pestat] mean and std.dev: (434.46, 180.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1703)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 688056 reads in 199.263 CPU sec, 6.319 real sec
sorting block 102, #reads = 1065509 mem = 536881088 peak = 1127305216
[M::mem_process_seqs] Processed 688212 reads in 133.389 CPU sec, 4.226 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 280775, 15, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 285, 1385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3765)
[M::mem_pestat] mean and std.dev: (663.39, 743.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4955)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 293, 422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 888)
[M::mem_pestat] mean and std.dev: (315.61, 155.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1121)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (804, 1645, 1714)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3534)
[M::mem_pestat] mean and std.dev: (1152.14, 597.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4444)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 308, 880)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2148)
[M::mem_pestat] mean and std.dev: (424.42, 282.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2782)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 686708 sequences (100000230 bp) in 2.708 CPU sec, 2.852 real sec...
[M::process] read 686098 sequences (100000163 bp) in 1.690 CPU sec, 1.686 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 280014, 16, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 350, 975)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2489)
[M::mem_pestat] mean and std.dev: (533.50, 409.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3246)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 296, 426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 896)
[M::mem_pestat] mean and std.dev: (319.03, 157.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1131)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (25, 756, 4158)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12424)
[M::mem_pestat] mean and std.dev: (2461.25, 3494.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16557)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 284, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 996)
[M::mem_pestat] mean and std.dev: (283.36, 134.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1272)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 687780 reads in 198.943 CPU sec, 6.340 real sec
sorting block 103, #reads = 1066669 mem = 536878814 peak = 1127305216
[M::mem_process_seqs] Processed 686942 reads in 131.349 CPU sec, 4.434 real sec
sorting block 104, #reads = 1065950 mem = 536878155 peak = 1127305216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 279731, 11, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 417, 1325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3537)
[M::mem_pestat] mean and std.dev: (744.36, 728.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4643)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 299, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 909)
[M::mem_pestat] mean and std.dev: (322.01, 159.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1148)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (318, 830, 4256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12132)
[M::mem_pestat] mean and std.dev: (1513.18, 1709.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16070)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 236, 412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 784)
[M::mem_pestat] mean and std.dev: (257.74, 95.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 970)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 685418 sequences (100000116 bp) in 2.703 CPU sec, 2.829 real sec...
[M::process] read 684928 sequences (100000086 bp) in 2.010 CPU sec, 2.010 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 279289, 9, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 388, 784)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2030)
[M::mem_pestat] mean and std.dev: (462.10, 326.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2653)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 302, 433)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 911)
[M::mem_pestat] mean and std.dev: (324.24, 159.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1150)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (258, 406, 1328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3468)
[M::mem_pestat] mean and std.dev: (642.53, 581.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4538)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 686708 reads in 206.548 CPU sec, 6.796 real sec
[M::mem_process_seqs] Processed 686098 reads in 136.340 CPU sec, 4.343 real sec
sorting block 105, #reads = 1063785 mem = 536881860 peak = 1127305216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 279873, 5, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 265, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 956)
[M::mem_pestat] mean and std.dev: (308.02, 202.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1209)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 303, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 916)
[M::mem_pestat] mean and std.dev: (326.34, 160.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1156)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 265, 621)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1435)
[M::mem_pestat] mean and std.dev: (302.60, 245.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1842)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 684956 sequences (100000046 bp) in 3.134 CPU sec, 3.308 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 278640, 13, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 278, 810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2072)
[M::mem_pestat] mean and std.dev: (343.95, 304.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2703)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 684478 sequences (100000224 bp) in 2.140 CPU sec, 2.162 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (198, 305, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 918)
[M::mem_pestat] mean and std.dev: (328.11, 161.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1158)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 348, 737)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1911)
[M::mem_pestat] mean and std.dev: (387.75, 306.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2498)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 390, 540)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1148)
[M::mem_pestat] mean and std.dev: (387.78, 216.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1452)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 685418 reads in 212.417 CPU sec, 6.761 real sec
sorting block 106, #reads = 1063942 mem = 536878197 peak = 1127305216
[M::mem_process_seqs] Processed 684928 reads in 150.162 CPU sec, 4.786 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 279464, 14, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 294, 627)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1479)
[M::mem_pestat] mean and std.dev: (367.41, 272.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1905)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 306, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 918)
[M::mem_pestat] mean and std.dev: (328.62, 161.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1158)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (370, 582, 1336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3268)
[M::mem_pestat] mean and std.dev: (824.86, 684.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4234)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 271, 401)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 841)
[M::mem_pestat] mean and std.dev: (307.94, 173.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1061)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 684210 sequences (100000033 bp) in 2.559 CPU sec, 2.708 real sec...
[M::process] read 683836 sequences (100000200 bp) in 1.680 CPU sec, 1.687 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 278922, 11, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 303, 378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (251.66, 108.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 945)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 308, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 920)
[M::mem_pestat] mean and std.dev: (330.62, 162.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1160)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (78, 217, 1080)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3084)
[M::mem_pestat] mean and std.dev: (628.36, 771.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4086)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (309, 457, 711)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1515)
[M::mem_pestat] mean and std.dev: (470.56, 294.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1917)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684956 reads in 210.802 CPU sec, 6.724 real sec
sorting block 107, #reads = 1064586 mem = 536880266 peak = 1127305216
[M::mem_process_seqs] Processed 684478 reads in 139.440 CPU sec, 4.697 real sec
sorting block 108, #reads = 1065309 mem = 536880086 peak = 1127305216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 278808, 20, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 326, 379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 673)
[M::mem_pestat] mean and std.dev: (324.76, 129.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 844)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 308, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 929)
[M::mem_pestat] mean and std.dev: (331.79, 163.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1172)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 1184, 1254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3348)
[M::mem_pestat] mean and std.dev: (643.12, 516.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4395)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 464, 1013)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2547)
[M::mem_pestat] mean and std.dev: (602.82, 497.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3314)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 684138 sequences (100000275 bp) in 2.748 CPU sec, 2.885 real sec...
[M::process] read 684172 sequences (100000148 bp) in 1.820 CPU sec, 1.827 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 278436, 13, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 246, 994)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2664)
[M::mem_pestat] mean and std.dev: (484.79, 449.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3499)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 312, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 928)
[M::mem_pestat] mean and std.dev: (333.68, 163.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1170)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (538, 817, 2706)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7042)
[M::mem_pestat] mean and std.dev: (1387.54, 1257.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9210)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 277, 400)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 784)
[M::mem_pestat] mean and std.dev: (313.79, 151.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 976)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684210 reads in 212.313 CPU sec, 6.999 real sec
[M::mem_process_seqs] Processed 683836 reads in 137.475 CPU sec, 4.386 real sec
sorting block 109, #reads = 1065205 mem = 536881294 peak = 1127305216
[M::process] read 683174 sequences (100000256 bp) in 2.838 CPU sec, 3.005 real sec...
[M::process] read 682962 sequences (100000099 bp) in 1.908 CPU sec, 1.917 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 279281, 15, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 241, 488)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1132)
[M::mem_pestat] mean and std.dev: (271.97, 146.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1454)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 309, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 926)
[M::mem_pestat] mean and std.dev: (331.53, 162.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1168)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (815, 1765, 2785)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6725)
[M::mem_pestat] mean and std.dev: (1915.00, 1473.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8695)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (287, 474, 587)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1187)
[M::mem_pestat] mean and std.dev: (459.09, 228.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1487)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684172 reads in 123.815 CPU sec, 3.933 real sec
sorting block 110, #reads = 1064507 mem = 536878965 peak = 1127305216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 278554, 9, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 241, 383)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 801)
[M::mem_pestat] mean and std.dev: (293.49, 164.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1010)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 310, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 926)
[M::mem_pestat] mean and std.dev: (331.93, 162.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1168)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 305, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 914)
[M::mem_pestat] mean and std.dev: (322.89, 146.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1137)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 278854, 4, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 442, 578)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1306)
[M::mem_pestat] mean and std.dev: (408.27, 251.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1670)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 315, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 936)
[M::mem_pestat] mean and std.dev: (337.24, 165.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1180)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 224, 380)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (248.89, 90.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 947)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682880 sequences (100000130 bp) in 2.119 CPU sec, 2.121 real sec...
[M::mem_process_seqs] Processed 684138 reads in 330.572 CPU sec, 10.611 real sec
[M::mem_process_seqs] Processed 683174 reads in 161.280 CPU sec, 5.151 real sec
sorting block 111, #reads = 1065022 mem = 536882012 peak = 1127305216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 278479, 12, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 384, 710)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1766)
[M::mem_pestat] mean and std.dev: (386.17, 276.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2294)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 316, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 934)
[M::mem_pestat] mean and std.dev: (337.94, 165.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1177)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (306, 643, 1021)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2451)
[M::mem_pestat] mean and std.dev: (793.67, 722.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3685)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (260, 344, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 863)
[M::mem_pestat] mean and std.dev: (341.00, 115.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1064)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682948 sequences (100000205 bp) in 2.885 CPU sec, 3.067 real sec...
[M::process] read 684002 sequences (100000208 bp) in 1.937 CPU sec, 1.942 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 278512, 5, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (254, 378, 966)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2390)
[M::mem_pestat] mean and std.dev: (572.10, 594.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3102)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 317, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 944)
[M::mem_pestat] mean and std.dev: (339.87, 167.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1190)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 242, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 994)
[M::mem_pestat] mean and std.dev: (285.62, 139.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1258)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682962 reads in 198.292 CPU sec, 6.307 real sec
[M::mem_process_seqs] Processed 682880 reads in 133.701 CPU sec, 4.252 real sec
sorting block 112, #reads = 1066936 mem = 536880638 peak = 1127305216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 278096, 7, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 250, 1063)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2909)
[M::mem_pestat] mean and std.dev: (344.17, 345.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3832)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 318, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 956)
[M::mem_pestat] mean and std.dev: (342.08, 169.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1206)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 318, 563)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1317)
[M::mem_pestat] mean and std.dev: (357.18, 219.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1694)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 691136 sequences (100000216 bp) in 2.723 CPU sec, 2.877 real sec...
[M::process] read 691096 sequences (100000008 bp) in 1.961 CPU sec, 1.962 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 278306, 9, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 284, 478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1102)
[M::mem_pestat] mean and std.dev: (283.52, 137.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1414)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 309, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 936)
[M::mem_pestat] mean and std.dev: (335.25, 168.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1181)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 311, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 972)
[M::mem_pestat] mean and std.dev: (350.19, 214.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1231)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682948 reads in 210.011 CPU sec, 6.794 real sec
sorting block 113, #reads = 1065306 mem = 536878914 peak = 1127305216
[M::mem_process_seqs] Processed 684002 reads in 143.519 CPU sec, 4.571 real sec
[M::process] read 689832 sequences (100000267 bp) in 2.560 CPU sec, 2.694 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 281318, 8, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 325, 406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 930)
[M::mem_pestat] mean and std.dev: (293.37, 182.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1192)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 275, 404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 854)
[M::mem_pestat] mean and std.dev: (302.81, 154.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1079)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 324, 583)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1399)
[M::mem_pestat] mean and std.dev: (331.03, 212.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1807)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 691136 reads in 123.783 CPU sec, 4.012 real sec
sorting block 114, #reads = 1060661 mem = 536882157 peak = 1127305216
[M::process] read 689134 sequences (100000100 bp) in 2.342 CPU sec, 2.639 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 281216, 5, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 232, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 905)
[M::mem_pestat] mean and std.dev: (266.38, 128.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1142)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 275, 402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 848)
[M::mem_pestat] mean and std.dev: (301.73, 152.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1071)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (300, 367, 871)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2013)
[M::mem_pestat] mean and std.dev: (436.28, 264.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2584)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 688374 sequences (100000128 bp) in 1.977 CPU sec, 1.983 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 280876, 11, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 196, 407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 909)
[M::mem_pestat] mean and std.dev: (255.67, 174.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1160)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 281, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 863)
[M::mem_pestat] mean and std.dev: (306.36, 153.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1090)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (17, 139, 763)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2255)
[M::mem_pestat] mean and std.dev: (290.60, 335.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3001)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 293, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (289.95, 126.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 832)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 691096 reads in 227.406 CPU sec, 7.294 real sec
[M::mem_process_seqs] Processed 689832 reads in 247.730 CPU sec, 7.948 real sec
sorting block 115, #reads = 1067506 mem = 536878084 peak = 1127305216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 281011, 6, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 339, 509)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1093)
[M::mem_pestat] mean and std.dev: (323.39, 172.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1385)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 284, 414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 874)
[M::mem_pestat] mean and std.dev: (309.79, 155.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1104)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 309, 856)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2166)
[M::mem_pestat] mean and std.dev: (430.41, 387.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2821)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 687864 sequences (100000191 bp) in 2.777 CPU sec, 2.969 real sec...
[M::process] read 687104 sequences (100000109 bp) in 1.481 CPU sec, 1.488 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 280640, 14, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (260, 323, 546)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1118)
[M::mem_pestat] mean and std.dev: (382.19, 202.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1404)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 288, 416)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 874)
[M::mem_pestat] mean and std.dev: (311.94, 154.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1103)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 1557, 2542)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7320)
[M::mem_pestat] mean and std.dev: (1404.79, 1006.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9709)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 342, 393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 809)
[M::mem_pestat] mean and std.dev: (291.58, 123.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1017)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 689134 reads in 192.691 CPU sec, 6.142 real sec
sorting block 116, #reads = 1071916 mem = 536879478 peak = 1127305216
[M::mem_process_seqs] Processed 688374 reads in 125.809 CPU sec, 4.232 real sec
sorting block 117, #reads = 1073400 mem = 536878893 peak = 1127305216
[M::process] read 687052 sequences (100000272 bp) in 2.592 CPU sec, 2.733 real sec...
[M::process] read 686454 sequences (100000299 bp) in 1.862 CPU sec, 1.862 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 280060, 5, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 245, 390)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 832)
[M::mem_pestat] mean and std.dev: (283.24, 168.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1053)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 295, 423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 887)
[M::mem_pestat] mean and std.dev: (317.32, 155.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1119)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 499, 841)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2023)
[M::mem_pestat] mean and std.dev: (447.23, 276.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2614)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 687104 reads in 111.385 CPU sec, 3.535 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 280247, 18, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 286, 608)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1426)
[M::mem_pestat] mean and std.dev: (332.26, 204.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1835)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 292, 420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 884)
[M::mem_pestat] mean and std.dev: (314.79, 155.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1116)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 190, 909)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2449)
[M::mem_pestat] mean and std.dev: (620.56, 767.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3691)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (305, 431, 558)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1064)
[M::mem_pestat] mean and std.dev: (330.97, 132.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1317)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 280240, 7, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 332, 542)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1236)
[M::mem_pestat] mean and std.dev: (357.85, 231.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1583)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 297, 424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 888)
[M::mem_pestat] mean and std.dev: (318.27, 156.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1120)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 291, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 965)
[M::mem_pestat] mean and std.dev: (266.08, 118.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1226)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 687864 reads in 305.689 CPU sec, 9.954 real sec
[M::process] read 686376 sequences (100000150 bp) in 2.169 CPU sec, 2.186 real sec...
sorting block 118, #reads = 1070773 mem = 536878148 peak = 1127305216
[M::mem_process_seqs] Processed 687052 reads in 151.704 CPU sec, 4.845 real sec
sorting block 119, #reads = 1071400 mem = 536880072 peak = 1127305216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 280514, 13, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 326, 518)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1108)
[M::mem_pestat] mean and std.dev: (373.87, 250.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1403)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 300, 429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 899)
[M::mem_pestat] mean and std.dev: (321.51, 157.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1134)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (375, 967, 5644)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 16182)
[M::mem_pestat] mean and std.dev: (2391.46, 2307.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 21451)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 283, 413)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 863)
[M::mem_pestat] mean and std.dev: (280.82, 122.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1088)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 686902 sequences (100000283 bp) in 2.995 CPU sec, 3.137 real sec...
[M::process] read 686516 sequences (100000239 bp) in 1.890 CPU sec, 1.897 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 279529, 6, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 319, 410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 846)
[M::mem_pestat] mean and std.dev: (305.86, 143.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1064)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 301, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 902)
[M::mem_pestat] mean and std.dev: (322.35, 158.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1138)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 316, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 652)
[M::mem_pestat] mean and std.dev: (278.22, 91.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 802)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 686454 reads in 204.622 CPU sec, 6.503 real sec
[M::mem_process_seqs] Processed 686376 reads in 134.995 CPU sec, 4.295 real sec
sorting block 120, #reads = 1069221 mem = 536882073 peak = 1127305216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 280099, 9, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 200, 587)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1443)
[M::mem_pestat] mean and std.dev: (311.34, 257.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1871)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 297, 425)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 891)
[M::mem_pestat] mean and std.dev: (318.78, 156.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1124)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 378, 611)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1417)
[M::mem_pestat] mean and std.dev: (376.67, 212.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1820)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 686276 sequences (100000183 bp) in 3.039 CPU sec, 3.248 real sec...
[M::process] read 685846 sequences (100000242 bp) in 1.918 CPU sec, 1.925 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 280027, 7, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 347, 495)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1031)
[M::mem_pestat] mean and std.dev: (341.78, 175.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1299)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 300, 429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 901)
[M::mem_pestat] mean and std.dev: (321.25, 157.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1137)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 322, 846)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2054)
[M::mem_pestat] mean and std.dev: (561.37, 535.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2703)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 686902 reads in 198.764 CPU sec, 6.315 real sec
[M::mem_process_seqs] Processed 686516 reads in 130.816 CPU sec, 4.155 real sec
sorting block 121, #reads = 1069763 mem = 536880797 peak = 1127305216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 279686, 14, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (255, 340, 486)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 948)
[M::mem_pestat] mean and std.dev: (307.60, 118.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1179)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 300, 428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 896)
[M::mem_pestat] mean and std.dev: (320.99, 156.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1130)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (456, 2258, 2484)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6540)
[M::mem_pestat] mean and std.dev: (1530.79, 1031.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8568)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 244, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (263.24, 118.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 861)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 686228 sequences (100000154 bp) in 3.220 CPU sec, 3.416 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 279728, 21, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (358, 618, 1667)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4285)
[M::mem_pestat] mean and std.dev: (733.15, 618.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5594)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 303, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 900)
[M::mem_pestat] mean and std.dev: (323.14, 157.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1135)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 541, 817)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2139)
[M::mem_pestat] mean and std.dev: (550.00, 393.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2800)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 221, 412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 910)
[M::mem_pestat] mean and std.dev: (249.41, 132.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1159)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 686616 sequences (100000026 bp) in 1.930 CPU sec, 1.925 real sec...
[M::mem_process_seqs] Processed 686276 reads in 197.025 CPU sec, 6.260 real sec
sorting block 122, #reads = 1069195 mem = 536879255 peak = 1127305216
[M::mem_process_seqs] Processed 685846 reads in 131.462 CPU sec, 4.166 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 280151, 7, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 239, 476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1114)
[M::mem_pestat] mean and std.dev: (255.61, 134.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1433)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 299, 426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 890)
[M::mem_pestat] mean and std.dev: (320.25, 156.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1122)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 342, 506)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1068)
[M::mem_pestat] mean and std.dev: (365.58, 205.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1349)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 123, #reads = 1069248 mem = 536879763 peak = 1127305216
[M::process] read 685958 sequences (100000009 bp) in 2.954 CPU sec, 3.140 real sec...
[M::process] read 684826 sequences (100000128 bp) in 1.944 CPU sec, 1.953 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 279757, 5, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 230, 1138)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3038)
[M::mem_pestat] mean and std.dev: (410.75, 410.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3988)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 296, 423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 885)
[M::mem_pestat] mean and std.dev: (318.10, 156.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1116)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 339, 486)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1002)
[M::mem_pestat] mean and std.dev: (294.23, 123.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1260)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 686228 reads in 200.759 CPU sec, 6.381 real sec
[M::mem_process_seqs] Processed 686616 reads in 132.858 CPU sec, 4.214 real sec
sorting block 124, #reads = 1068902 mem = 536880212 peak = 1127305216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 279127, 12, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 438, 1601)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4291)
[M::mem_pestat] mean and std.dev: (1023.65, 1195.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5805)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 302, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 906)
[M::mem_pestat] mean and std.dev: (323.82, 158.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1143)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (534, 804, 804)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1344)
[M::mem_pestat] mean and std.dev: (656.50, 394.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2236)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 320, 507)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1021)
[M::mem_pestat] mean and std.dev: (364.60, 177.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1278)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 685110 sequences (100000238 bp) in 2.906 CPU sec, 3.081 real sec...
[M::process] read 684754 sequences (100000025 bp) in 1.980 CPU sec, 1.976 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 278869, 10, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 342, 491)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1031)
[M::mem_pestat] mean and std.dev: (396.83, 251.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1403)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 307, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 915)
[M::mem_pestat] mean and std.dev: (327.62, 159.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1154)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 2015, 4930)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 14434)
[M::mem_pestat] mean and std.dev: (2350.90, 1999.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 19186)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 471, 1104)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2838)
[M::mem_pestat] mean and std.dev: (496.14, 407.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3705)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 685958 reads in 212.314 CPU sec, 6.757 real sec
[M::mem_process_seqs] Processed 684826 reads in 143.189 CPU sec, 4.552 real sec
sorting block 125, #reads = 1068022 mem = 536884173 peak = 1127305216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 278653, 11, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 259, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 708)
[M::mem_pestat] mean and std.dev: (256.42, 101.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 887)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 306, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 912)
[M::mem_pestat] mean and std.dev: (326.55, 158.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1150)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (465, 929, 1815)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4515)
[M::mem_pestat] mean and std.dev: (1171.91, 982.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5865)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 370, 554)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1292)
[M::mem_pestat] mean and std.dev: (399.78, 323.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1692)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 684732 sequences (100000037 bp) in 3.094 CPU sec, 3.242 real sec...
[M::process] read 685304 sequences (100000154 bp) in 1.980 CPU sec, 1.984 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 278420, 14, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 260, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709)
[M::mem_pestat] mean and std.dev: (278.39, 158.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 911)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 308, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 922)
[M::mem_pestat] mean and std.dev: (329.39, 160.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1163)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (416, 591, 995)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2153)
[M::mem_pestat] mean and std.dev: (684.00, 390.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2732)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 343, 620)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1398)
[M::mem_pestat] mean and std.dev: (393.44, 280.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1787)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 685110 reads in 220.602 CPU sec, 7.013 real sec
sorting block 126, #reads = 1065816 mem = 536878942 peak = 1127305216
[M::mem_process_seqs] Processed 684754 reads in 154.684 CPU sec, 4.933 real sec
[M::process] read 684250 sequences (100000192 bp) in 2.481 CPU sec, 2.602 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 278882, 15, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 241, 394)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 900)
[M::mem_pestat] mean and std.dev: (237.70, 116.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1153)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 306, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 918)
[M::mem_pestat] mean and std.dev: (328.67, 161.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1158)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (381, 1150, 1400)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3438)
[M::mem_pestat] mean and std.dev: (910.50, 792.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4457)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 358, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 959)
[M::mem_pestat] mean and std.dev: (328.00, 165.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1205)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 684088 sequences (100000012 bp) in 1.515 CPU sec, 1.517 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 278906, 18, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 309, 428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 878)
[M::mem_pestat] mean and std.dev: (325.98, 162.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1103)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 301, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 901)
[M::mem_pestat] mean and std.dev: (324.03, 158.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1136)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (298, 639, 982)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2350)
[M::mem_pestat] mean and std.dev: (676.59, 523.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3034)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 276, 551)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1253)
[M::mem_pestat] mean and std.dev: (366.71, 272.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1604)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 278550, 17, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 375, 655)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1503)
[M::mem_pestat] mean and std.dev: (419.29, 293.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1927)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 306, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 908)
[M::mem_pestat] mean and std.dev: (327.83, 158.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1144)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (633, 1559, 2329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5721)
[M::mem_pestat] mean and std.dev: (1892.24, 1446.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7680)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 373, 530)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1160)
[M::mem_pestat] mean and std.dev: (359.77, 181.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1475)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684732 reads in 310.104 CPU sec, 9.938 real sec
sorting block 127, #reads = 1063508 mem = 536878477 peak = 1127305216
[M::mem_process_seqs] Processed 685304 reads in 233.063 CPU sec, 7.485 real sec
[M::mem_process_seqs] Processed 684250 reads in 254.470 CPU sec, 8.188 real sec
sorting block 128, #reads = 1062970 mem = 536880793 peak = 1127305216
[M::process] read 684220 sequences (100000092 bp) in 3.022 CPU sec, 3.208 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 278660, 22, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 321, 818)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2008)
[M::mem_pestat] mean and std.dev: (429.86, 336.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2603)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 309, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 929)
[M::mem_pestat] mean and std.dev: (331.70, 162.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1172)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (706, 1767, 2809)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7015)
[M::mem_pestat] mean and std.dev: (1787.91, 1281.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9118)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 245, 570)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1378)
[M::mem_pestat] mean and std.dev: (278.13, 183.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1782)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 684192 sequences (100000099 bp) in 2.300 CPU sec, 2.379 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 279071, 9, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 477, 646)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1466)
[M::mem_pestat] mean and std.dev: (423.77, 224.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1876)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 308, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 920)
[M::mem_pestat] mean and std.dev: (330.40, 161.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1160)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 407, 515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1133)
[M::mem_pestat] mean and std.dev: (321.67, 152.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1442)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684088 reads in 191.607 CPU sec, 6.109 real sec
sorting block 129, #reads = 1063596 mem = 536878787 peak = 1127305216
[M::mem_process_seqs] Processed 684220 reads in 131.410 CPU sec, 4.145 real sec
[M::process] read 683962 sequences (100000256 bp) in 2.325 CPU sec, 2.423 real sec...
sorting block 130, #reads = 1064174 mem = 536880113 peak = 1127305216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 279017, 12, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 374, 678)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1650)
[M::mem_pestat] mean and std.dev: (336.71, 203.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2136)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 309, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 926)
[M::mem_pestat] mean and std.dev: (331.59, 162.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1168)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (575, 829, 1863)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4439)
[M::mem_pestat] mean and std.dev: (929.50, 657.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5727)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 287, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (247.72, 131.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 973)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 684272 sequences (100000147 bp) in 2.651 CPU sec, 2.754 real sec...
[M::process] read 688716 sequences (100000095 bp) in 1.940 CPU sec, 1.937 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 279015, 14, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 337, 671)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1523)
[M::mem_pestat] mean and std.dev: (366.85, 280.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1949)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 309, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 927)
[M::mem_pestat] mean and std.dev: (332.58, 163.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1169)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (502, 865, 941)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1819)
[M::mem_pestat] mean and std.dev: (729.00, 349.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2258)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 323, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 628)
[M::mem_pestat] mean and std.dev: (278.50, 130.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 802)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684192 reads in 218.762 CPU sec, 6.965 real sec
[M::mem_process_seqs] Processed 683962 reads in 143.865 CPU sec, 4.579 real sec
sorting block 131, #reads = 1062240 mem = 536887302 peak = 1127305216
[M::process] read 696538 sequences (100000286 bp) in 2.672 CPU sec, 2.804 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 278993, 19, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 321, 396)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 806)
[M::mem_pestat] mean and std.dev: (315.70, 142.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1011)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 308, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 926)
[M::mem_pestat] mean and std.dev: (331.91, 163.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1168)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (365, 585, 886)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1928)
[M::mem_pestat] mean and std.dev: (591.06, 380.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2449)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 269, 524)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1222)
[M::mem_pestat] mean and std.dev: (352.68, 266.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1571)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694590 sequences (100000017 bp) in 1.966 CPU sec, 1.973 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 282980, 9, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 222, 412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 894)
[M::mem_pestat] mean and std.dev: (276.04, 139.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1135)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 251, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (279.03, 141.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 975)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 270, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 650)
[M::mem_pestat] mean and std.dev: (254.26, 105.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 807)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 280050, 8, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 251, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 656)
[M::mem_pestat] mean and std.dev: (244.52, 103.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 825)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 284, 415)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 877)
[M::mem_pestat] mean and std.dev: (311.20, 158.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1108)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 326, 660)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1634)
[M::mem_pestat] mean and std.dev: (407.58, 311.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2121)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684272 reads in 314.678 CPU sec, 10.147 real sec
[M::mem_process_seqs] Processed 696538 reads in 234.543 CPU sec, 7.516 real sec
sorting block 132, #reads = 1059329 mem = 536880703 peak = 1127305216
[M::mem_process_seqs] Processed 688716 reads in 263.301 CPU sec, 8.450 real sec
[M::process] read 693104 sequences (100000113 bp) in 2.496 CPU sec, 2.639 real sec...
sorting block 133, #reads = 1060429 mem = 536878942 peak = 1127305216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 282977, 8, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 255, 422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 850)
[M::mem_pestat] mean and std.dev: (306.12, 170.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1064)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 260, 381)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 801)
[M::mem_pestat] mean and std.dev: (286.80, 144.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1011)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 348, 822)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2088)
[M::mem_pestat] mean and std.dev: (465.14, 447.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2721)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 691838 sequences (100000298 bp) in 2.305 CPU sec, 2.370 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 282413, 15, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 344, 499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1107)
[M::mem_pestat] mean and std.dev: (297.34, 161.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1411)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 266, 389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 819)
[M::mem_pestat] mean and std.dev: (291.66, 145.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1034)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (483, 663, 911)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1767)
[M::mem_pestat] mean and std.dev: (669.86, 419.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2350)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 386, 679)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1689)
[M::mem_pestat] mean and std.dev: (353.16, 208.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2194)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 691052 sequences (100000204 bp) in 1.964 CPU sec, 1.970 real sec...
[M::mem_process_seqs] Processed 694590 reads in 217.099 CPU sec, 6.899 real sec
[M::mem_process_seqs] Processed 693104 reads in 143.885 CPU sec, 4.788 real sec
sorting block 134, #reads = 1061211 mem = 536879901 peak = 1127305216
[M::process] read 690274 sequences (100000138 bp) in 2.630 CPU sec, 2.765 real sec...
[M::process] read 689684 sequences (100000127 bp) in 1.976 CPU sec, 1.985 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 280919, 13, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 237, 308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 558)
[M::mem_pestat] mean and std.dev: (239.00, 106.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 683)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 281, 407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 857)
[M::mem_pestat] mean and std.dev: (304.68, 150.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1082)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1282, 1752, 2848)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5980)
[M::mem_pestat] mean and std.dev: (2091.46, 1241.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7546)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 319, 602)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1378)
[M::mem_pestat] mean and std.dev: (363.92, 225.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1766)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 690274 reads in 127.537 CPU sec, 4.072 real sec
sorting block 135, #reads = 1065380 mem = 536880431 peak = 1127305216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 281659, 5, 19)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 256, 403)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 895)
[M::mem_pestat] mean and std.dev: (255.11, 153.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1141)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 272, 394)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 828)
[M::mem_pestat] mean and std.dev: (295.59, 146.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1045)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 328, 2949)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8353)
[M::mem_pestat] mean and std.dev: (1329.84, 1622.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11055)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281596, 8, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 352, 1315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3547)
[M::mem_pestat] mean and std.dev: (799.41, 983.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4735)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 276, 400)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 842)
[M::mem_pestat] mean and std.dev: (299.10, 147.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1063)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 287, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 745)
[M::mem_pestat] mean and std.dev: (273.19, 121.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 939)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 688596 sequences (100000069 bp) in 2.071 CPU sec, 2.077 real sec...
[M::mem_process_seqs] Processed 691838 reads in 348.672 CPU sec, 11.332 real sec
[M::mem_process_seqs] Processed 691052 reads in 272.691 CPU sec, 8.715 real sec
sorting block 136, #reads = 1063300 mem = 536879624 peak = 1127305216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281042, 7, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 242, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1003)
[M::mem_pestat] mean and std.dev: (237.74, 112.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1282)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 283, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 861)
[M::mem_pestat] mean and std.dev: (305.66, 150.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1087)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 245, 1116)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3006)
[M::mem_pestat] mean and std.dev: (577.71, 680.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3951)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 688598 sequences (100000262 bp) in 2.613 CPU sec, 2.723 real sec...
[M::process] read 688734 sequences (100000102 bp) in 1.994 CPU sec, 1.999 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 280693, 11, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 333, 1638)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4434)
[M::mem_pestat] mean and std.dev: (580.06, 917.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5832)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 291, 418)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 880)
[M::mem_pestat] mean and std.dev: (312.26, 153.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1111)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 441, 4615)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13515)
[M::mem_pestat] mean and std.dev: (1992.64, 2862.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17965)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 236, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 549)
[M::mem_pestat] mean and std.dev: (233.68, 82.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 667)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 689684 reads in 210.147 CPU sec, 6.682 real sec
sorting block 137, #reads = 1063750 mem = 536880767 peak = 1127305216
[M::mem_process_seqs] Processed 688596 reads in 139.079 CPU sec, 4.437 real sec
sorting block 138, #reads = 1063963 mem = 536886071 peak = 1127305216
[M::process] read 688028 sequences (100000029 bp) in 2.949 CPU sec, 3.113 real sec...
[M::process] read 687756 sequences (100000049 bp) in 1.980 CPU sec, 1.979 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 280743, 7, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 204, 581)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1439)
[M::mem_pestat] mean and std.dev: (298.31, 326.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1868)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 288, 417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 879)
[M::mem_pestat] mean and std.dev: (311.00, 153.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1110)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (281, 404, 787)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1799)
[M::mem_pestat] mean and std.dev: (502.90, 349.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2305)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 688734 reads in 122.694 CPU sec, 3.930 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 280118, 7, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 258, 1120)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3026)
[M::mem_pestat] mean and std.dev: (523.84, 565.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3979)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 288, 417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 879)
[M::mem_pestat] mean and std.dev: (311.21, 153.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1110)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 299, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 949)
[M::mem_pestat] mean and std.dev: (267.19, 111.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1199)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 688578 sequences (100000086 bp) in 1.902 CPU sec, 1.908 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 280281, 13, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 352, 506)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1080)
[M::mem_pestat] mean and std.dev: (331.63, 183.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1367)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 293, 423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 891)
[M::mem_pestat] mean and std.dev: (315.93, 155.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1125)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (384, 737, 1447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3573)
[M::mem_pestat] mean and std.dev: (663.27, 416.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4636)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (305, 382, 1577)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4121)
[M::mem_pestat] mean and std.dev: (616.76, 600.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5393)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 688598 reads in 332.208 CPU sec, 10.598 real sec
sorting block 139, #reads = 1063573 mem = 536880304 peak = 1127305216
[M::mem_process_seqs] Processed 688028 reads in 156.472 CPU sec, 5.284 real sec
[M::process] read 686476 sequences (100000083 bp) in 2.557 CPU sec, 2.677 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 279842, 13, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 304, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 883)
[M::mem_pestat] mean and std.dev: (309.52, 148.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1104)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 292, 421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 885)
[M::mem_pestat] mean and std.dev: (314.69, 154.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1117)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (97, 323, 2697)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7897)
[M::mem_pestat] mean and std.dev: (1282.31, 1552.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10497)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 340, 627)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1489)
[M::mem_pestat] mean and std.dev: (367.25, 259.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1920)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 685568 sequences (100000048 bp) in 1.878 CPU sec, 1.883 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 280315, 15, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 253, 625)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1581)
[M::mem_pestat] mean and std.dev: (372.79, 339.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2059)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 284, 410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 858)
[M::mem_pestat] mean and std.dev: (308.16, 152.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1082)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 922, 1600)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4452)
[M::mem_pestat] mean and std.dev: (764.15, 667.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5878)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 403, 818)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1978)
[M::mem_pestat] mean and std.dev: (461.42, 281.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2558)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 687756 reads in 204.547 CPU sec, 6.743 real sec
sorting block 140, #reads = 1063154 mem = 536877806 peak = 1127305216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 279128, 22, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 214, 379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 829)
[M::mem_pestat] mean and std.dev: (268.59, 157.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1054)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 294, 419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 873)
[M::mem_pestat] mean and std.dev: (315.21, 152.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1100)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (354, 574, 2404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6504)
[M::mem_pestat] mean and std.dev: (1559.81, 1852.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8968)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 295, 543)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1213)
[M::mem_pestat] mean and std.dev: (304.88, 173.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1548)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 685154 sequences (100000204 bp) in 2.150 CPU sec, 2.153 real sec...
[M::mem_process_seqs] Processed 688578 reads in 224.174 CPU sec, 7.113 real sec
sorting block 141, #reads = 1064378 mem = 536879789 peak = 1151111168
[M::mem_process_seqs] Processed 686476 reads in 247.895 CPU sec, 8.134 real sec
[M::process] read 684540 sequences (100000012 bp) in 2.593 CPU sec, 2.710 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 279175, 10, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 303, 551)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1367)
[M::mem_pestat] mean and std.dev: (309.93, 211.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1775)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 301, 428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 892)
[M::mem_pestat] mean and std.dev: (321.51, 155.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1124)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 657, 1960)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5528)
[M::mem_pestat] mean and std.dev: (888.80, 792.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7312)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 373, 621)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1445)
[M::mem_pestat] mean and std.dev: (424.45, 304.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1857)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 684522 sequences (100000048 bp) in 1.808 CPU sec, 1.808 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 278431, 11, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 294, 433)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 965)
[M::mem_pestat] mean and std.dev: (277.80, 149.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1231)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 305, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 892)
[M::mem_pestat] mean and std.dev: (324.06, 154.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1123)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 352, 1121)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3071)
[M::mem_pestat] mean and std.dev: (530.40, 410.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4046)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 320, 397)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 727)
[M::mem_pestat] mean and std.dev: (300.56, 115.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 892)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 278883, 11, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 234, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 713)
[M::mem_pestat] mean and std.dev: (227.50, 122.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 904)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 304, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 897)
[M::mem_pestat] mean and std.dev: (324.35, 156.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1130)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (328, 328, 1178)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2878)
[M::mem_pestat] mean and std.dev: (666.91, 512.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3728)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (274, 383, 566)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1150)
[M::mem_pestat] mean and std.dev: (448.94, 268.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1522)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 685568 reads in 290.856 CPU sec, 9.525 real sec
sorting block 142, #reads = 1061473 mem = 536879004 peak = 1151111168
[M::mem_process_seqs] Processed 684540 reads in 215.773 CPU sec, 6.913 real sec
[M::mem_process_seqs] Processed 685154 reads in 237.571 CPU sec, 7.631 real sec
sorting block 143, #reads = 1063256 mem = 536879105 peak = 1151111168
[M::process] read 684904 sequences (100000054 bp) in 2.199 CPU sec, 2.333 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 278368, 9, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 339, 647)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1547)
[M::mem_pestat] mean and std.dev: (409.64, 329.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1997)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 304, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 895)
[M::mem_pestat] mean and std.dev: (324.65, 156.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1127)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 319, 422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 808)
[M::mem_pestat] mean and std.dev: (318.84, 142.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1001)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 684192 sequences (100000085 bp) in 1.813 CPU sec, 1.906 real sec...
[M::process] read 683848 sequences (100000088 bp) in 1.380 CPU sec, 1.379 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 278445, 10, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 319, 492)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1080)
[M::mem_pestat] mean and std.dev: (321.56, 183.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1374)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 299, 424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 878)
[M::mem_pestat] mean and std.dev: (320.06, 153.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1105)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (540, 847, 3151)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8373)
[M::mem_pestat] mean and std.dev: (1390.20, 1190.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10984)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 271, 537)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1227)
[M::mem_pestat] mean and std.dev: (363.32, 251.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1572)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684522 reads in 193.854 CPU sec, 6.192 real sec
sorting block 144, #reads = 1065082 mem = 536878691 peak = 1151111168
[M::mem_process_seqs] Processed 684904 reads in 125.903 CPU sec, 4.007 real sec
sorting block 145, #reads = 1065112 mem = 536881017 peak = 1151111168
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 278195, 16, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 338, 634)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1470)
[M::mem_pestat] mean and std.dev: (409.76, 328.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1888)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 304, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 890)
[M::mem_pestat] mean and std.dev: (324.53, 155.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1120)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (123, 637, 2008)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5778)
[M::mem_pestat] mean and std.dev: (891.07, 892.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7663)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 376, 629)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1445)
[M::mem_pestat] mean and std.dev: (384.78, 200.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1853)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683472 sequences (100000037 bp) in 2.342 CPU sec, 2.453 real sec...
[M::process] read 683112 sequences (100000195 bp) in 1.690 CPU sec, 1.695 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 278781, 13, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 337, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 921)
[M::mem_pestat] mean and std.dev: (292.97, 129.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1162)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 307, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 891)
[M::mem_pestat] mean and std.dev: (326.46, 156.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1121)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (80, 482, 1547)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4481)
[M::mem_pestat] mean and std.dev: (847.17, 898.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5948)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 369, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 921)
[M::mem_pestat] mean and std.dev: (333.74, 168.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1154)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684192 reads in 184.877 CPU sec, 5.881 real sec
[M::mem_process_seqs] Processed 683848 reads in 124.001 CPU sec, 3.962 real sec
sorting block 146, #reads = 1064419 mem = 536881825 peak = 1151111168
[M::process] read 682766 sequences (100000001 bp) in 1.867 CPU sec, 1.959 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 278843, 21, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 259, 429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1007)
[M::mem_pestat] mean and std.dev: (297.15, 186.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1296)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 309, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 904)
[M::mem_pestat] mean and std.dev: (329.77, 159.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1138)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (486, 2204, 5695)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 16113)
[M::mem_pestat] mean and std.dev: (2482.95, 2094.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 21322)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 215, 1399)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3815)
[M::mem_pestat] mean and std.dev: (522.43, 524.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5023)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682600 sequences (100000030 bp) in 1.400 CPU sec, 1.405 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 278493, 6, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 352, 651)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1521)
[M::mem_pestat] mean and std.dev: (383.88, 282.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1956)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 315, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 930)
[M::mem_pestat] mean and std.dev: (335.93, 163.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1172)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 268, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1025)
[M::mem_pestat] mean and std.dev: (323.93, 201.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1302)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 278715, 5, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 252, 775)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2049)
[M::mem_pestat] mean and std.dev: (270.17, 220.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2686)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 316, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 926)
[M::mem_pestat] mean and std.dev: (337.09, 163.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1166)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 383, 519)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1069)
[M::mem_pestat] mean and std.dev: (362.71, 172.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1344)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683472 reads in 245.654 CPU sec, 7.852 real sec
[M::mem_process_seqs] Processed 683112 reads in 186.863 CPU sec, 6.005 real sec
sorting block 147, #reads = 1065856 mem = 536879703 peak = 1151111168
[M::mem_process_seqs] Processed 682766 reads in 201.963 CPU sec, 6.501 real sec
[M::process] read 682270 sequences (100000076 bp) in 2.268 CPU sec, 2.410 real sec...
sorting block 148, #reads = 1065640 mem = 536883283 peak = 1151111168
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 278246, 6, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 343, 1088)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2920)
[M::mem_pestat] mean and std.dev: (518.72, 469.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3836)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 319, 451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 939)
[M::mem_pestat] mean and std.dev: (340.15, 166.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1183)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 396, 1467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3893)
[M::mem_pestat] mean and std.dev: (640.34, 566.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5106)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 223236 sequences (32611286 bp) in 0.818 CPU sec, 0.858 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 277926, 14, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 316, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 942)
[M::mem_pestat] mean and std.dev: (325.57, 152.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1189)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 321, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 949)
[M::mem_pestat] mean and std.dev: (342.75, 168.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1196)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (621, 967, 1153)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2217)
[M::mem_pestat] mean and std.dev: (835.21, 352.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2749)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (282, 364, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 813)
[M::mem_pestat] mean and std.dev: (337.88, 115.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 990)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682600 reads in 168.467 CPU sec, 5.436 real sec
[M::mem_process_seqs] Processed 682270 reads in 109.676 CPU sec, 3.540 real sec
sorting block 149, #reads = 1066392 mem = 536876990 peak = 1151111168
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (13, 91058, 5, 8)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 227, 479)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1011)
[M::mem_pestat] mean and std.dev: (255.64, 89.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1277)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 307, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 916)
[M::mem_pestat] mean and std.dev: (329.62, 162.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1155)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::mem_process_seqs] Processed 223236 reads in 33.901 CPU sec, 1.145 real sec
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 159882536
overall: 70325878784 mem 27042.145 user 516.764 sys 908.473 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1136_253-T1-TDNA-1_A23MHWWLT4_1.L004\tPU:L004\tSM:1136_253-T1-TDNA-1_A23MHWWLT4_1\tLB:1136_253-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1136_253-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1136_253-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 908.508 sec; CPU: 27558.913 sec
sorting block 150, #reads = 948365 mem = 478801376 peak = 1186324480
uniq header count 1
merging 151 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31 max 192
algo: util-sort
license: sentieon:util=1
output file size: 9600820296
output reads: 161115046
bam_mem_sort: 151 calls 90.521 user 2.063 sys 93.072 real
bam_write: 151 calls 53.181 user 2.698 sys 63.634 real
execute: 1 calls 35.651 user 2.170 sys 964.237 real
merge_files: 1 calls 35.637 user 2.133 sys 54.880 real
parse_chunk: 2415 calls 107.126 user 27.654 sys 139.473 real
read_chunk: 6522 calls 52.754 user 47.696 sys 847.898 real
sort_block: 1 calls 35.544 user 46.942 sys 823.250 real
write_chunk: 4105 calls 35.246 user 1.782 sys 53.815 real
overall: 3475116032 mem 2190.079 user 102.536 sys 964.257 real
ls: cannot access '*.cram': No such file or directory