This software is licensed to bgold@natera.com by Sentieon Inc.
cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1136_7GC-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 1572.576 CPU sec, 62.679 real sec
[M::process] read 711198 sequences (100000164 bp) in 1.586 CPU sec, 1.595 real sec...
[M::process] read 709574 sequences (100000185 bp) in 1.796 CPU sec, 2.247 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 289886, 24, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 320, 805)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2105)
[M::mem_pestat] mean and std.dev: (335.76, 267.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2755)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 211, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 619)
[M::mem_pestat] mean and std.dev: (232.75, 113.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 777)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (297, 676, 2040)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5526)
[M::mem_pestat] mean and std.dev: (1279.87, 1437.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7269)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 481, 950)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2378)
[M::mem_pestat] mean and std.dev: (534.02, 456.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3092)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708980 sequences (100000006 bp) in 1.817 CPU sec, 2.214 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 289065, 36, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 248, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1057)
[M::mem_pestat] mean and std.dev: (313.28, 227.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1354)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 214, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 629)
[M::mem_pestat] mean and std.dev: (235.92, 115.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 790)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (492, 1006, 1464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3408)
[M::mem_pestat] mean and std.dev: (1139.53, 866.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4607)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (286, 394, 1579)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4165)
[M::mem_pestat] mean and std.dev: (829.55, 914.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5458)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708326 sequences (100000082 bp) in 1.837 CPU sec, 2.292 real sec...
[M::mem_process_seqs] Processed 711198 reads in 192.265 CPU sec, 7.223 real sec
[M::mem_process_seqs] Processed 709574 reads in 132.865 CPU sec, 5.068 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (81, 288925, 36, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 300, 658)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1604)
[M::mem_pestat] mean and std.dev: (357.65, 259.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2077)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 216, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 642)
[M::mem_pestat] mean and std.dev: (239.13, 117.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 807)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (420, 776, 1113)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2499)
[M::mem_pestat] mean and std.dev: (803.47, 622.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3295)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 370, 827)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2027)
[M::mem_pestat] mean and std.dev: (493.41, 338.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2627)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 0, #reads = 1088881 mem = 536886595 peak = 573722624
[M::process] read 707772 sequences (100000292 bp) in 2.521 CPU sec, 3.090 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 289056, 33, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 286, 1213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3225)
[M::mem_pestat] mean and std.dev: (682.65, 805.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4231)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 219, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 652)
[M::mem_pestat] mean and std.dev: (241.45, 118.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 820)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (447, 985, 1581)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3849)
[M::mem_pestat] mean and std.dev: (1033.70, 821.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4983)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 425, 865)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2207)
[M::mem_pestat] mean and std.dev: (570.62, 594.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2950)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 708980 reads in 192.226 CPU sec, 6.879 real sec
[M::process] read 707352 sequences (100000239 bp) in 2.056 CPU sec, 2.460 real sec...
[M::mem_process_seqs] Processed 708326 reads in 133.905 CPU sec, 4.982 real sec
sorting block 1, #reads = 1087919 mem = 536883345 peak = 735727616
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 288245, 28, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 426, 1304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3542)
[M::mem_pestat] mean and std.dev: (766.41, 861.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4661)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 220, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 659)
[M::mem_pestat] mean and std.dev: (243.58, 120.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 829)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (407, 1043, 1358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3260)
[M::mem_pestat] mean and std.dev: (832.65, 599.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4211)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 269, 855)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2193)
[M::mem_pestat] mean and std.dev: (433.94, 395.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2862)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706930 sequences (100000295 bp) in 2.687 CPU sec, 3.527 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 288403, 37, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 410, 932)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2406)
[M::mem_pestat] mean and std.dev: (532.96, 477.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3143)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 222, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 665)
[M::mem_pestat] mean and std.dev: (245.02, 121.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 837)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (462, 623, 2311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6009)
[M::mem_pestat] mean and std.dev: (1096.88, 1065.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7858)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 230, 497)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1197)
[M::mem_pestat] mean and std.dev: (237.72, 154.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1547)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707772 reads in 190.069 CPU sec, 6.917 real sec
[M::process] read 707040 sequences (100000123 bp) in 2.292 CPU sec, 2.564 real sec...
[M::mem_process_seqs] Processed 707352 reads in 133.866 CPU sec, 5.084 real sec
sorting block 2, #reads = 1087842 mem = 536879344 peak = 882032640
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 288717, 28, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 265, 429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1007)
[M::mem_pestat] mean and std.dev: (308.63, 214.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1296)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 223, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 669)
[M::mem_pestat] mean and std.dev: (246.02, 121.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 842)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (318, 703, 1050)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2514)
[M::mem_pestat] mean and std.dev: (676.04, 457.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3246)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 396, 1590)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4442)
[M::mem_pestat] mean and std.dev: (1000.73, 1268.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6077)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706480 sequences (100000192 bp) in 2.991 CPU sec, 3.749 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 288504, 42, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 240, 870)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2244)
[M::mem_pestat] mean and std.dev: (433.14, 517.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2931)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 221, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 669)
[M::mem_pestat] mean and std.dev: (245.70, 122.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 842)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (129, 571, 1009)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2769)
[M::mem_pestat] mean and std.dev: (665.38, 674.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3649)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 318, 1183)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3257)
[M::mem_pestat] mean and std.dev: (579.34, 713.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4294)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706930 reads in 188.328 CPU sec, 6.929 real sec
sorting block 3, #reads = 1087622 mem = 536881015 peak = 882032640
[M::mem_process_seqs] Processed 707040 reads in 133.672 CPU sec, 5.035 real sec
[M::process] read 706184 sequences (100000299 bp) in 2.692 CPU sec, 3.279 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 288065, 32, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 336, 1079)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2841)
[M::mem_pestat] mean and std.dev: (506.03, 474.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3722)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 223, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 675)
[M::mem_pestat] mean and std.dev: (247.61, 123.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 850)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (494, 836, 1621)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3875)
[M::mem_pestat] mean and std.dev: (1183.44, 1026.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5288)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 404, 1012)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2614)
[M::mem_pestat] mean and std.dev: (508.59, 417.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3415)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 4, #reads = 1088273 mem = 536885693 peak = 882032640
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 288443, 45, 81)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 413, 1039)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2715)
[M::mem_pestat] mean and std.dev: (574.38, 420.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3553)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 224, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 676)
[M::mem_pestat] mean and std.dev: (248.20, 123.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 851)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 918, 1855)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5037)
[M::mem_pestat] mean and std.dev: (1136.23, 1060.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6628)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 274, 624)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1544)
[M::mem_pestat] mean and std.dev: (342.65, 266.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2004)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705720 sequences (100000253 bp) in 2.732 CPU sec, 3.366 real sec...
[M::mem_process_seqs] Processed 706480 reads in 189.629 CPU sec, 6.905 real sec
[M::mem_process_seqs] Processed 706184 reads in 134.279 CPU sec, 4.906 real sec
[M::process] read 704988 sequences (100000251 bp) in 2.444 CPU sec, 2.971 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 288034, 30, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 1083, 2196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6110)
[M::mem_pestat] mean and std.dev: (1114.65, 1010.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8067)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 226, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (249.38, 123.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 859)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 1421, 2730)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7736)
[M::mem_pestat] mean and std.dev: (1598.37, 1268.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10239)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 568, 1094)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2872)
[M::mem_pestat] mean and std.dev: (660.08, 578.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3761)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 5, #reads = 1086447 mem = 536878753 peak = 882032640
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 287476, 30, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 268, 408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 864)
[M::mem_pestat] mean and std.dev: (279.66, 158.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1092)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 227, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (250.45, 123.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 860)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (512, 959, 2317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5927)
[M::mem_pestat] mean and std.dev: (1441.31, 1182.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7732)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 335, 881)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2233)
[M::mem_pestat] mean and std.dev: (477.69, 398.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2909)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704724 sequences (100000037 bp) in 2.986 CPU sec, 3.973 real sec...
[M::mem_process_seqs] Processed 705720 reads in 185.709 CPU sec, 6.706 real sec
sorting block 6, #reads = 1088417 mem = 536882467 peak = 882032640
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 287519, 45, 84)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 480, 821)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2139)
[M::mem_pestat] mean and std.dev: (393.37, 301.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2798)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 704928 sequences (100000249 bp) in 2.972 CPU sec, 3.636 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (153, 228, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (251.81, 125.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 865)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 527, 1334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3594)
[M::mem_pestat] mean and std.dev: (807.20, 682.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4724)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 342, 624)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1432)
[M::mem_pestat] mean and std.dev: (405.18, 324.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1836)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704724 reads in 107.319 CPU sec, 4.255 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (85, 287502, 28, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 400, 1571)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4365)
[M::mem_pestat] mean and std.dev: (905.51, 1014.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5762)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 228, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (251.96, 125.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 872)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (635, 1651, 4044)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10862)
[M::mem_pestat] mean and std.dev: (2339.11, 2196.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14271)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 360, 1011)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2613)
[M::mem_pestat] mean and std.dev: (525.95, 447.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3414)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703872 sequences (100000243 bp) in 2.774 CPU sec, 3.681 real sec...
[M::mem_process_seqs] Processed 704928 reads in 105.582 CPU sec, 4.244 real sec
[M::mem_process_seqs] Processed 704988 reads in 343.341 CPU sec, 13.358 real sec
sorting block 7, #reads = 1086354 mem = 536883226 peak = 882032640
[M::process] read 704160 sequences (100000110 bp) in 3.084 CPU sec, 3.527 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 287007, 31, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 224, 1102)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2990)
[M::mem_pestat] mean and std.dev: (513.04, 596.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3934)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 229, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (253.25, 125.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (559, 795, 3026)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7960)
[M::mem_pestat] mean and std.dev: (2189.03, 2427.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11900)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 680, 1433)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3847)
[M::mem_pestat] mean and std.dev: (906.55, 894.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5054)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703872 reads in 108.202 CPU sec, 4.795 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 287476, 48, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 432, 746)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1876)
[M::mem_pestat] mean and std.dev: (474.09, 378.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2441)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 229, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (253.19, 125.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (363, 848, 1332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3270)
[M::mem_pestat] mean and std.dev: (896.64, 753.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4239)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 352, 1290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3468)
[M::mem_pestat] mean and std.dev: (729.38, 717.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4557)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704608 sequences (100000038 bp) in 2.885 CPU sec, 3.715 real sec...
sorting block 8, #reads = 1086399 mem = 536876150 peak = 882032640
[M::mem_process_seqs] Processed 704160 reads in 107.626 CPU sec, 4.169 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 287911, 23, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 297, 842)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2124)
[M::mem_pestat] mean and std.dev: (473.71, 407.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2765)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 228, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (252.68, 125.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 873)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (579, 771, 1406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3060)
[M::mem_pestat] mean and std.dev: (922.48, 644.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3887)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 337, 821)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2065)
[M::mem_pestat] mean and std.dev: (464.97, 401.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2687)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703636 sequences (100000109 bp) in 2.583 CPU sec, 3.378 real sec...
[M::mem_process_seqs] Processed 704608 reads in 106.733 CPU sec, 4.223 real sec
sorting block 9, #reads = 1086069 mem = 536879382 peak = 882032640
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 287240, 30, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 332, 478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 986)
[M::mem_pestat] mean and std.dev: (312.21, 159.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1240)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 230, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 694)
[M::mem_pestat] mean and std.dev: (254.14, 126.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 874)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (388, 604, 1469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3631)
[M::mem_pestat] mean and std.dev: (758.70, 600.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4712)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 296, 901)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2375)
[M::mem_pestat] mean and std.dev: (465.31, 434.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3112)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703492 sequences (100000095 bp) in 2.917 CPU sec, 4.191 real sec...
[M::mem_process_seqs] Processed 703636 reads in 106.970 CPU sec, 4.500 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 287280, 48, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 327, 522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1170)
[M::mem_pestat] mean and std.dev: (349.80, 209.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1494)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 231, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (255.06, 126.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (448, 891, 2175)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5629)
[M::mem_pestat] mean and std.dev: (1331.60, 1243.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7356)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 467, 1876)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5174)
[M::mem_pestat] mean and std.dev: (1069.08, 1192.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6823)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702732 sequences (100000133 bp) in 3.173 CPU sec, 4.103 real sec...
[M::mem_process_seqs] Processed 703492 reads in 107.144 CPU sec, 4.201 real sec
sorting block 10, #reads = 1086301 mem = 536879811 peak = 882032640
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 287881, 36, 91)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 401, 1376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3782)
[M::mem_pestat] mean and std.dev: (785.84, 865.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4985)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 233, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 702)
[M::mem_pestat] mean and std.dev: (256.71, 127.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 884)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (294, 1200, 1473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3831)
[M::mem_pestat] mean and std.dev: (863.78, 693.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5010)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 458, 1476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3958)
[M::mem_pestat] mean and std.dev: (750.79, 748.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5199)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702456 sequences (100000059 bp) in 2.945 CPU sec, 3.765 real sec...
[M::mem_process_seqs] Processed 702732 reads in 108.985 CPU sec, 4.580 real sec
sorting block 11, #reads = 1086901 mem = 536877947 peak = 882032640
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (84, 286000, 45, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 429, 1130)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3074)
[M::mem_pestat] mean and std.dev: (626.34, 629.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4046)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 233, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 702)
[M::mem_pestat] mean and std.dev: (256.43, 126.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 884)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (61, 606, 2429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7165)
[M::mem_pestat] mean and std.dev: (1205.07, 1638.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9533)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 521, 1183)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3057)
[M::mem_pestat] mean and std.dev: (610.80, 531.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3994)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702058 sequences (100000002 bp) in 2.751 CPU sec, 3.452 real sec...
[M::mem_process_seqs] Processed 702456 reads in 109.574 CPU sec, 4.217 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 286974, 39, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (270, 469, 1354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3522)
[M::mem_pestat] mean and std.dev: (799.65, 823.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4606)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 235, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (257.44, 126.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 881)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (333, 1150, 6157)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 17805)
[M::mem_pestat] mean and std.dev: (2914.56, 2894.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 23629)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 505, 1112)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2856)
[M::mem_pestat] mean and std.dev: (614.75, 541.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3728)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700864 sequences (100000006 bp) in 2.770 CPU sec, 3.412 real sec...
sorting block 12, #reads = 1085244 mem = 536880052 peak = 882032640
[M::mem_process_seqs] Processed 702058 reads in 107.860 CPU sec, 4.263 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 286826, 35, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 295, 597)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1401)
[M::mem_pestat] mean and std.dev: (309.00, 176.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1803)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 236, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (257.26, 124.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 874)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (422, 920, 1330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3146)
[M::mem_pestat] mean and std.dev: (923.15, 684.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4054)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 729, 1551)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4159)
[M::mem_pestat] mean and std.dev: (795.95, 779.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5463)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701098 sequences (100000235 bp) in 2.763 CPU sec, 3.461 real sec...
[M::mem_process_seqs] Processed 700864 reads in 107.252 CPU sec, 4.272 real sec
sorting block 13, #reads = 1085025 mem = 536880974 peak = 882032640
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 286344, 37, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 331, 1041)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2751)
[M::mem_pestat] mean and std.dev: (527.27, 538.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3606)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 237, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (258.37, 125.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (547, 1099, 1413)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3145)
[M::mem_pestat] mean and std.dev: (1053.08, 622.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4011)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 398, 958)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2544)
[M::mem_pestat] mean and std.dev: (533.87, 519.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3337)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701194 sequences (100000078 bp) in 2.804 CPU sec, 3.709 real sec...
[M::mem_process_seqs] Processed 701098 reads in 109.714 CPU sec, 4.267 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (79, 285776, 30, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 274, 581)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1407)
[M::mem_pestat] mean and std.dev: (386.01, 336.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1820)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (257.42, 125.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 878)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (388, 1257, 1804)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4636)
[M::mem_pestat] mean and std.dev: (1208.32, 1101.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6052)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 406, 1238)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3328)
[M::mem_pestat] mean and std.dev: (612.61, 649.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4373)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701648 sequences (100000062 bp) in 2.924 CPU sec, 3.578 real sec...
[M::mem_process_seqs] Processed 701194 reads in 111.031 CPU sec, 4.435 real sec
sorting block 14, #reads = 1083963 mem = 536878670 peak = 882032640
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 286679, 43, 87)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 512, 1084)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2800)
[M::mem_pestat] mean and std.dev: (620.00, 607.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3658)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 234, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 694)
[M::mem_pestat] mean and std.dev: (256.58, 125.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 873)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (405, 803, 2215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5835)
[M::mem_pestat] mean and std.dev: (1231.53, 1100.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7645)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 279, 572)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1304)
[M::mem_pestat] mean and std.dev: (374.85, 263.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1670)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701070 sequences (100000218 bp) in 3.030 CPU sec, 3.558 real sec...
[M::mem_process_seqs] Processed 701648 reads in 111.646 CPU sec, 4.368 real sec
sorting block 15, #reads = 1082235 mem = 536879683 peak = 882032640
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (84, 286175, 48, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 297, 631)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1499)
[M::mem_pestat] mean and std.dev: (369.79, 250.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1933)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 234, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 686)
[M::mem_pestat] mean and std.dev: (255.13, 123.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 862)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 474, 1435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3979)
[M::mem_pestat] mean and std.dev: (618.00, 689.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5251)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 366, 1328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3584)
[M::mem_pestat] mean and std.dev: (777.52, 817.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4712)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701266 sequences (100000070 bp) in 3.037 CPU sec, 3.502 real sec...
[M::mem_process_seqs] Processed 701070 reads in 109.933 CPU sec, 4.042 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 286709, 22, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 363, 686)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1708)
[M::mem_pestat] mean and std.dev: (420.74, 342.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2219)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 233, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (254.53, 122.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (464, 583, 1320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3032)
[M::mem_pestat] mean and std.dev: (775.57, 540.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3888)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 395, 2437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6977)
[M::mem_pestat] mean and std.dev: (1070.19, 1629.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9247)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701290 sequences (100000192 bp) in 2.909 CPU sec, 3.559 real sec...
[M::mem_process_seqs] Processed 701266 reads in 110.031 CPU sec, 4.004 real sec
sorting block 16, #reads = 1081969 mem = 536878678 peak = 882032640
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 286172, 28, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 307, 1071)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2833)
[M::mem_pestat] mean and std.dev: (579.80, 598.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3714)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 234, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 686)
[M::mem_pestat] mean and std.dev: (255.18, 123.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 862)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 497, 1879)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5365)
[M::mem_pestat] mean and std.dev: (1042.43, 1156.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7108)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 272, 1101)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2999)
[M::mem_pestat] mean and std.dev: (676.78, 822.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3968)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701196 sequences (100000111 bp) in 2.749 CPU sec, 3.216 real sec...
[M::mem_process_seqs] Processed 701290 reads in 111.360 CPU sec, 4.083 real sec
sorting block 17, #reads = 1082130 mem = 536877964 peak = 882032640
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (81, 286005, 37, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 471, 1327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3613)
[M::mem_pestat] mean and std.dev: (749.14, 744.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4756)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 233, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (254.50, 123.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 861)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (399, 590, 1875)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4827)
[M::mem_pestat] mean and std.dev: (1059.20, 988.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6303)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 389, 611)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1483)
[M::mem_pestat] mean and std.dev: (427.78, 353.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1919)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700746 sequences (100000287 bp) in 3.034 CPU sec, 3.458 real sec...
[M::mem_process_seqs] Processed 701196 reads in 111.606 CPU sec, 3.992 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 285703, 55, 92)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 432, 1125)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2939)
[M::mem_pestat] mean and std.dev: (556.39, 487.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3846)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 236, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (258.25, 125.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 875)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 645, 1985)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5497)
[M::mem_pestat] mean and std.dev: (1092.92, 1146.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7253)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 399, 1057)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2813)
[M::mem_pestat] mean and std.dev: (691.78, 759.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3730)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701368 sequences (100000249 bp) in 2.954 CPU sec, 3.295 real sec...
[M::mem_process_seqs] Processed 700746 reads in 113.321 CPU sec, 3.984 real sec
sorting block 18, #reads = 1081451 mem = 536881808 peak = 882032640
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 286454, 37, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 275, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 996)
[M::mem_pestat] mean and std.dev: (292.33, 201.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1270)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 234, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (256.84, 125.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 874)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (354, 742, 1410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3522)
[M::mem_pestat] mean and std.dev: (686.61, 558.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4578)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 300, 886)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2216)
[M::mem_pestat] mean and std.dev: (431.50, 325.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2881)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700958 sequences (100000094 bp) in 2.989 CPU sec, 3.413 real sec...
[M::mem_process_seqs] Processed 701368 reads in 110.236 CPU sec, 3.794 real sec
[M::process] read 700928 sequences (100000022 bp) in 2.574 CPU sec, 2.901 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (83, 286393, 33, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 324, 770)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1926)
[M::mem_pestat] mean and std.dev: (435.07, 392.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2504)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 234, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (257.35, 126.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 878)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (404, 937, 1968)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5096)
[M::mem_pestat] mean and std.dev: (1190.12, 1167.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6660)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 326, 718)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1746)
[M::mem_pestat] mean and std.dev: (418.03, 335.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2260)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 19, #reads = 1079266 mem = 536880835 peak = 882032640
[M::mem_process_seqs] Processed 700958 reads in 112.215 CPU sec, 3.883 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 286930, 44, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 378, 1205)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3185)
[M::mem_pestat] mean and std.dev: (653.88, 657.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4175)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701)
[M::mem_pestat] mean and std.dev: (258.20, 127.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 882)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 500, 1000)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2568)
[M::mem_pestat] mean and std.dev: (505.74, 430.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3352)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 347, 555)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1155)
[M::mem_pestat] mean and std.dev: (319.55, 131.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1455)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705194 sequences (100000173 bp) in 2.816 CPU sec, 3.102 real sec...
[M::mem_process_seqs] Processed 700928 reads in 111.766 CPU sec, 3.936 real sec
sorting block 20, #reads = 1081121 mem = 536878460 peak = 882032640
[M::process] read 710420 sequences (100000259 bp) in 2.662 CPU sec, 2.873 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 287414, 34, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 227, 516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1252)
[M::mem_pestat] mean and std.dev: (315.78, 283.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1620)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 225, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (248.69, 123.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 848)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (447, 896, 1929)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4893)
[M::mem_pestat] mean and std.dev: (1117.71, 836.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6375)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 395, 871)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2109)
[M::mem_pestat] mean and std.dev: (622.57, 490.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2728)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705194 reads in 116.587 CPU sec, 3.946 real sec
sorting block 21, #reads = 1081424 mem = 536879707 peak = 882032640
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 289473, 21, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 306, 882)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2276)
[M::mem_pestat] mean and std.dev: (469.41, 402.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2973)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 213, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 629)
[M::mem_pestat] mean and std.dev: (235.75, 116.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 790)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (350, 434, 1066)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2498)
[M::mem_pestat] mean and std.dev: (614.33, 458.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3214)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 266, 738)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1874)
[M::mem_pestat] mean and std.dev: (449.56, 405.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2442)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 709020 sequences (100000236 bp) in 3.285 CPU sec, 3.572 real sec...
[M::mem_process_seqs] Processed 710420 reads in 106.926 CPU sec, 3.573 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 288463, 30, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 238, 727)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1837)
[M::mem_pestat] mean and std.dev: (424.13, 406.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2392)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 216, 311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 639)
[M::mem_pestat] mean and std.dev: (238.23, 117.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 803)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (344, 747, 1828)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4796)
[M::mem_pestat] mean and std.dev: (1201.90, 1178.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6280)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 276, 577)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1393)
[M::mem_pestat] mean and std.dev: (383.02, 323.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1801)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708046 sequences (100000101 bp) in 3.088 CPU sec, 3.383 real sec...
[M::mem_process_seqs] Processed 709020 reads in 103.123 CPU sec, 3.433 real sec
sorting block 22, #reads = 1082830 mem = 536876625 peak = 882032640
[M::process] read 706962 sequences (100000198 bp) in 2.473 CPU sec, 2.663 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 288834, 48, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 333, 1088)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2898)
[M::mem_pestat] mean and std.dev: (605.30, 615.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3803)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 219, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 655)
[M::mem_pestat] mean and std.dev: (242.46, 120.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 824)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (342, 480, 1188)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2880)
[M::mem_pestat] mean and std.dev: (761.00, 644.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3726)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 354, 1066)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2780)
[M::mem_pestat] mean and std.dev: (555.28, 538.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3637)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 23, #reads = 1088275 mem = 536884224 peak = 882032640
[M::process] read 706802 sequences (100000283 bp) in 2.441 CPU sec, 2.578 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 288396, 33, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 306, 516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1106)
[M::mem_pestat] mean and std.dev: (345.10, 181.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1401)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 221, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 663)
[M::mem_pestat] mean and std.dev: (244.74, 120.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (629, 1168, 2369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5849)
[M::mem_pestat] mean and std.dev: (1372.57, 1167.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7589)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 359, 889)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2217)
[M::mem_pestat] mean and std.dev: (408.24, 336.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2881)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 708046 reads in 178.119 CPU sec, 5.703 real sec
[M::mem_process_seqs] Processed 706962 reads in 124.288 CPU sec, 3.934 real sec
[M::process] read 707118 sequences (100000036 bp) in 2.848 CPU sec, 3.028 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 288132, 30, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 343, 487)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 919)
[M::mem_pestat] mean and std.dev: (335.57, 147.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1135)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 222, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 663)
[M::mem_pestat] mean and std.dev: (244.93, 120.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (579, 1433, 3325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8817)
[M::mem_pestat] mean and std.dev: (2051.70, 2048.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11563)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 333, 725)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1797)
[M::mem_pestat] mean and std.dev: (460.75, 361.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2333)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 24, #reads = 1088438 mem = 536881314 peak = 882032640
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 288294, 26, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 350, 778)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1910)
[M::mem_pestat] mean and std.dev: (481.19, 424.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2476)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 221, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 669)
[M::mem_pestat] mean and std.dev: (245.64, 122.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 842)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (386, 628, 2021)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5291)
[M::mem_pestat] mean and std.dev: (1141.35, 983.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6926)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 392, 638)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1486)
[M::mem_pestat] mean and std.dev: (400.44, 282.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1910)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706862 sequences (100000246 bp) in 2.894 CPU sec, 3.085 real sec...
[M::mem_process_seqs] Processed 706802 reads in 172.305 CPU sec, 5.507 real sec
[M::mem_process_seqs] Processed 707118 reads in 120.146 CPU sec, 3.798 real sec
sorting block 25, #reads = 1089471 mem = 536880228 peak = 882032640
[M::process] read 706570 sequences (100000071 bp) in 2.637 CPU sec, 2.771 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 288537, 50, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 479, 1528)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4216)
[M::mem_pestat] mean and std.dev: (865.33, 885.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5560)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 222, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 672)
[M::mem_pestat] mean and std.dev: (246.46, 122.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 846)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (815, 1451, 2355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5435)
[M::mem_pestat] mean and std.dev: (1483.37, 942.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6975)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 258, 552)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1330)
[M::mem_pestat] mean and std.dev: (293.24, 227.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1719)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706164 sequences (100000019 bp) in 2.662 CPU sec, 2.821 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 288842, 22, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 402, 1130)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2970)
[M::mem_pestat] mean and std.dev: (673.43, 671.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3890)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 223, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 672)
[M::mem_pestat] mean and std.dev: (246.81, 122.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 846)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (458, 1909, 3653)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10043)
[M::mem_pestat] mean and std.dev: (2275.18, 2126.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13238)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 407, 743)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1861)
[M::mem_pestat] mean and std.dev: (437.22, 354.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2420)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706862 reads in 168.196 CPU sec, 5.357 real sec
sorting block 26, #reads = 1088479 mem = 536881180 peak = 882032640
[M::process] read 705592 sequences (100000097 bp) in 2.337 CPU sec, 2.410 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 288151, 32, 87)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 299, 749)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1933)
[M::mem_pestat] mean and std.dev: (335.18, 301.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2525)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 224, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 673)
[M::mem_pestat] mean and std.dev: (247.63, 123.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 847)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (538, 985, 2235)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5629)
[M::mem_pestat] mean and std.dev: (1252.35, 1024.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7326)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 391, 1043)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2653)
[M::mem_pestat] mean and std.dev: (643.74, 558.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3458)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706164 reads in 96.493 CPU sec, 3.052 real sec
[M::process] read 705650 sequences (100000001 bp) in 1.827 CPU sec, 1.839 real sec...
sorting block 27, #reads = 1088520 mem = 536879181 peak = 882032640
[M::mem_process_seqs] Processed 706570 reads in 246.986 CPU sec, 7.830 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 287685, 41, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (330, 598, 757)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1611)
[M::mem_pestat] mean and std.dev: (441.27, 243.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2038)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 225, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (248.81, 124.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 855)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (458, 1022, 1922)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4850)
[M::mem_pestat] mean and std.dev: (1138.70, 893.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6314)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 312, 661)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1639)
[M::mem_pestat] mean and std.dev: (401.10, 315.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2128)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705002 sequences (100000263 bp) in 2.824 CPU sec, 2.908 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 288347, 23, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 288, 497)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1157)
[M::mem_pestat] mean and std.dev: (322.86, 231.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1487)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 225, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (249.38, 124.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 859)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (341, 497, 1120)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2678)
[M::mem_pestat] mean and std.dev: (549.10, 387.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3457)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 368, 918)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2312)
[M::mem_pestat] mean and std.dev: (590.76, 561.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3009)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705592 reads in 180.017 CPU sec, 5.704 real sec
[M::mem_process_seqs] Processed 705650 reads in 110.004 CPU sec, 3.466 real sec
sorting block 28, #reads = 1087831 mem = 536878692 peak = 882032640
[M::process] read 704448 sequences (100000162 bp) in 2.827 CPU sec, 3.001 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 287232, 30, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (275, 412, 834)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1952)
[M::mem_pestat] mean and std.dev: (417.98, 238.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2511)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 227, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (249.88, 123.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 856)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (323, 611, 1211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2987)
[M::mem_pestat] mean and std.dev: (902.80, 744.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3882)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 370, 725)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1749)
[M::mem_pestat] mean and std.dev: (484.62, 377.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2261)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 29, #reads = 1087252 mem = 536877683 peak = 882032640
[M::process] read 704224 sequences (100000102 bp) in 2.101 CPU sec, 2.199 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 287601, 27, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 319, 1095)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2863)
[M::mem_pestat] mean and std.dev: (582.53, 619.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3747)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 228, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684)
[M::mem_pestat] mean and std.dev: (251.12, 124.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 861)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (516, 1106, 2450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6318)
[M::mem_pestat] mean and std.dev: (1737.48, 1510.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8252)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 259, 630)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1530)
[M::mem_pestat] mean and std.dev: (412.67, 367.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1980)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705002 reads in 157.875 CPU sec, 5.022 real sec
[M::process] read 704218 sequences (100000170 bp) in 1.520 CPU sec, 1.522 real sec...
[M::mem_process_seqs] Processed 704448 reads in 108.667 CPU sec, 3.442 real sec
sorting block 30, #reads = 1086551 mem = 536876195 peak = 882032640
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 286851, 47, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 313, 541)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1261)
[M::mem_pestat] mean and std.dev: (409.16, 332.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1737)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 229, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (251.96, 124.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 862)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (532, 919, 2635)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6841)
[M::mem_pestat] mean and std.dev: (1981.21, 2166.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10648)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 302, 1257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3395)
[M::mem_pestat] mean and std.dev: (738.21, 796.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4464)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703984 sequences (100000245 bp) in 2.466 CPU sec, 2.567 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 287665, 31, 81)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 281, 750)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1878)
[M::mem_pestat] mean and std.dev: (400.24, 349.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2442)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (252.39, 125.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (426, 609, 1021)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2211)
[M::mem_pestat] mean and std.dev: (628.93, 453.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2806)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (281, 612, 1064)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2630)
[M::mem_pestat] mean and std.dev: (644.71, 441.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3413)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704112 sequences (100000163 bp) in 1.660 CPU sec, 1.659 real sec...
[M::mem_process_seqs] Processed 704224 reads in 152.669 CPU sec, 4.853 real sec
[M::mem_process_seqs] Processed 704218 reads in 108.453 CPU sec, 3.457 real sec
sorting block 31, #reads = 1086501 mem = 536878714 peak = 882032640
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 287580, 65, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 342, 1330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3542)
[M::mem_pestat] mean and std.dev: (634.30, 665.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4648)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 229, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (252.61, 124.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (424, 1047, 2610)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6982)
[M::mem_pestat] mean and std.dev: (1421.98, 1591.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9168)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 290, 584)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1422)
[M::mem_pestat] mean and std.dev: (379.35, 265.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1841)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703774 sequences (100000125 bp) in 2.108 CPU sec, 2.196 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 287767, 37, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 380, 695)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1685)
[M::mem_pestat] mean and std.dev: (416.12, 267.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2180)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 229, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (252.53, 125.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 235, 1116)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3040)
[M::mem_pestat] mean and std.dev: (452.72, 516.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4002)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 336, 1237)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3295)
[M::mem_pestat] mean and std.dev: (581.77, 554.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4324)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703830 sequences (100000198 bp) in 1.620 CPU sec, 1.615 real sec...
[M::mem_process_seqs] Processed 703984 reads in 151.832 CPU sec, 4.834 real sec
sorting block 32, #reads = 1086668 mem = 536879534 peak = 882032640
[M::mem_process_seqs] Processed 704112 reads in 103.788 CPU sec, 3.299 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 287189, 35, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 325, 805)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2069)
[M::mem_pestat] mean and std.dev: (407.05, 402.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2701)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 230, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (253.42, 125.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 460, 1586)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4400)
[M::mem_pestat] mean and std.dev: (840.53, 1040.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5807)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 328, 635)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1569)
[M::mem_pestat] mean and std.dev: (411.30, 344.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2036)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703642 sequences (100000108 bp) in 2.291 CPU sec, 2.391 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 286864, 33, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 332, 2152)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6012)
[M::mem_pestat] mean and std.dev: (1281.68, 1621.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7942)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 229, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (253.02, 125.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (270, 473, 1241)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3183)
[M::mem_pestat] mean and std.dev: (515.10, 410.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4154)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 448, 854)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2086)
[M::mem_pestat] mean and std.dev: (506.02, 440.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2702)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703302 sequences (100000186 bp) in 1.485 CPU sec, 1.480 real sec...
[M::mem_process_seqs] Processed 703774 reads in 144.581 CPU sec, 4.598 real sec
sorting block 33, #reads = 1085919 mem = 536879907 peak = 882032640
[M::mem_process_seqs] Processed 703830 reads in 98.144 CPU sec, 3.119 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 287242, 19, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 269, 752)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1822)
[M::mem_pestat] mean and std.dev: (365.28, 322.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2357)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 230, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 694)
[M::mem_pestat] mean and std.dev: (253.63, 125.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 874)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (383, 702, 945)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2069)
[M::mem_pestat] mean and std.dev: (673.26, 473.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2631)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (258, 346, 606)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1302)
[M::mem_pestat] mean and std.dev: (368.91, 201.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1650)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 34, #reads = 1085096 mem = 536877527 peak = 996634624
[M::process] read 702552 sequences (100000020 bp) in 2.647 CPU sec, 2.853 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 287221, 34, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 319, 889)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2267)
[M::mem_pestat] mean and std.dev: (476.51, 466.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2956)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 231, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (254.18, 125.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 708, 1156)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2996)
[M::mem_pestat] mean and std.dev: (670.13, 523.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3916)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 319, 545)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1153)
[M::mem_pestat] mean and std.dev: (335.62, 196.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1457)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703642 reads in 145.818 CPU sec, 4.632 real sec
[M::process] read 702254 sequences (100000233 bp) in 1.601 CPU sec, 1.626 real sec...
[M::mem_process_seqs] Processed 703302 reads in 100.976 CPU sec, 3.196 real sec
sorting block 35, #reads = 1084757 mem = 536884198 peak = 996634624
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 287043, 26, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 434, 917)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2305)
[M::mem_pestat] mean and std.dev: (577.49, 482.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2999)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 232, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (254.98, 125.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 872)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (334, 681, 1097)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2623)
[M::mem_pestat] mean and std.dev: (556.62, 369.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3386)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (262, 489, 908)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2200)
[M::mem_pestat] mean and std.dev: (598.94, 455.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2846)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701844 sequences (100000110 bp) in 2.415 CPU sec, 2.555 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 286441, 47, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 271, 569)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1299)
[M::mem_pestat] mean and std.dev: (388.14, 296.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1664)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 233, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (255.34, 125.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 872)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (340, 724, 1312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3256)
[M::mem_pestat] mean and std.dev: (859.89, 655.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4228)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 544, 1171)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3013)
[M::mem_pestat] mean and std.dev: (631.53, 532.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3934)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702176 sequences (100000165 bp) in 1.600 CPU sec, 1.600 real sec...
[M::mem_process_seqs] Processed 702552 reads in 145.910 CPU sec, 4.635 real sec
[M::mem_process_seqs] Processed 702254 reads in 97.466 CPU sec, 3.093 real sec
sorting block 36, #reads = 1085475 mem = 536876776 peak = 996634624
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 286158, 31, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 252, 560)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1370)
[M::mem_pestat] mean and std.dev: (304.93, 236.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1775)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 233, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (255.24, 124.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 865)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (321, 489, 678)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1392)
[M::mem_pestat] mean and std.dev: (501.38, 368.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1976)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 331, 584)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1330)
[M::mem_pestat] mean and std.dev: (361.30, 228.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1703)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702046 sequences (100000207 bp) in 2.245 CPU sec, 2.338 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 286364, 49, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 243, 892)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2316)
[M::mem_pestat] mean and std.dev: (435.53, 456.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3028)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 232, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (254.63, 124.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 930, 2371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6625)
[M::mem_pestat] mean and std.dev: (1363.62, 1361.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8752)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 374, 743)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1777)
[M::mem_pestat] mean and std.dev: (513.11, 403.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2294)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702322 sequences (100000030 bp) in 1.509 CPU sec, 1.505 real sec...
[M::mem_process_seqs] Processed 701844 reads in 142.096 CPU sec, 4.515 real sec
sorting block 37, #reads = 1083908 mem = 536879207 peak = 996634624
[M::mem_process_seqs] Processed 702176 reads in 100.845 CPU sec, 3.219 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 286581, 32, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (132, 213, 515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1281)
[M::mem_pestat] mean and std.dev: (273.57, 205.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1664)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 232, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684)
[M::mem_pestat] mean and std.dev: (253.92, 123.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 860)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (390, 752, 1426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3498)
[M::mem_pestat] mean and std.dev: (950.83, 951.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4757)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 463, 1449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3993)
[M::mem_pestat] mean and std.dev: (765.06, 803.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5265)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 38, #reads = 1083809 mem = 536880179 peak = 996634624
[M::process] read 702096 sequences (100000081 bp) in 1.997 CPU sec, 2.098 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 286460, 36, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 366, 1169)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3211)
[M::mem_pestat] mean and std.dev: (630.38, 630.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4232)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 230, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 681)
[M::mem_pestat] mean and std.dev: (252.85, 123.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 856)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (543, 841, 1502)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3420)
[M::mem_pestat] mean and std.dev: (854.13, 530.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4379)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (300, 589, 2803)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7809)
[M::mem_pestat] mean and std.dev: (1625.43, 1947.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10312)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701698 sequences (100000149 bp) in 1.430 CPU sec, 1.429 real sec...
[M::mem_process_seqs] Processed 702046 reads in 139.583 CPU sec, 4.447 real sec
[M::mem_process_seqs] Processed 702322 reads in 93.932 CPU sec, 2.984 real sec
sorting block 39, #reads = 1083290 mem = 536880592 peak = 996634624
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 286566, 39, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 321, 1509)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4137)
[M::mem_pestat] mean and std.dev: (726.59, 887.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5451)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 232, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684)
[M::mem_pestat] mean and std.dev: (253.88, 124.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 860)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (390, 669, 1358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3294)
[M::mem_pestat] mean and std.dev: (804.94, 732.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4262)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 343, 583)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1291)
[M::mem_pestat] mean and std.dev: (310.86, 160.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1645)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701860 sequences (100000253 bp) in 2.504 CPU sec, 2.705 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 286890, 32, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 403, 856)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2146)
[M::mem_pestat] mean and std.dev: (465.79, 410.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2791)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 232, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (253.83, 122.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 857)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 786, 1954)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5412)
[M::mem_pestat] mean and std.dev: (1199.94, 1321.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7141)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 439, 784)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1944)
[M::mem_pestat] mean and std.dev: (502.38, 384.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2524)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702096 reads in 137.636 CPU sec, 4.382 real sec
[M::mem_process_seqs] Processed 701698 reads in 93.310 CPU sec, 2.950 real sec
[M::process] read 701184 sequences (100000009 bp) in 1.933 CPU sec, 2.006 real sec...
sorting block 40, #reads = 1082813 mem = 536877302 peak = 996634624
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 285823, 25, 86)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 340, 1034)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2668)
[M::mem_pestat] mean and std.dev: (599.48, 519.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3485)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 233, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (254.84, 124.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 865)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 1196, 4764)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13974)
[M::mem_pestat] mean and std.dev: (2222.88, 2410.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 18579)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 363, 744)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1740)
[M::mem_pestat] mean and std.dev: (450.41, 336.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2238)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701632 sequences (100000078 bp) in 2.313 CPU sec, 2.530 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 286273, 24, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 303, 703)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1675)
[M::mem_pestat] mean and std.dev: (395.79, 311.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2161)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 233, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (255.64, 124.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 869)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (462, 863, 2617)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6927)
[M::mem_pestat] mean and std.dev: (1220.78, 1076.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9082)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 299, 1203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3243)
[M::mem_pestat] mean and std.dev: (698.24, 806.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4263)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701860 reads in 137.313 CPU sec, 4.389 real sec
[M::mem_process_seqs] Processed 701184 reads in 92.918 CPU sec, 2.940 real sec
sorting block 41, #reads = 1082870 mem = 536879943 peak = 996634624
[M::process] read 701150 sequences (100000278 bp) in 1.682 CPU sec, 1.741 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 286372, 44, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 461, 1466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3998)
[M::mem_pestat] mean and std.dev: (873.00, 923.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5264)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 233, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697)
[M::mem_pestat] mean and std.dev: (256.54, 126.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 877)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 615, 1328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3612)
[M::mem_pestat] mean and std.dev: (770.69, 666.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4754)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 310, 778)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1888)
[M::mem_pestat] mean and std.dev: (422.79, 360.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2443)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 42, #reads = 1082001 mem = 536886987 peak = 996634624
[M::process] read 701404 sequences (100000214 bp) in 2.031 CPU sec, 2.116 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 286425, 34, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 371, 943)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2501)
[M::mem_pestat] mean and std.dev: (499.13, 504.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3280)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 234, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (257.06, 126.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 874)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (379, 628, 2337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6253)
[M::mem_pestat] mean and std.dev: (1406.53, 1596.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8211)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 256, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 974)
[M::mem_pestat] mean and std.dev: (275.16, 145.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1234)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701632 reads in 133.459 CPU sec, 4.246 real sec
[M::process] read 706882 sequences (100000139 bp) in 1.460 CPU sec, 1.458 real sec...
[M::mem_process_seqs] Processed 701150 reads in 90.150 CPU sec, 2.860 real sec
sorting block 43, #reads = 1082789 mem = 536878877 peak = 996634624
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 286641, 31, 84)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 276, 946)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2502)
[M::mem_pestat] mean and std.dev: (434.65, 468.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3280)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 234, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (257.61, 127.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 881)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (539, 1184, 2178)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5456)
[M::mem_pestat] mean and std.dev: (1193.22, 851.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7095)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 373, 686)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1602)
[M::mem_pestat] mean and std.dev: (461.62, 306.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2060)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 710608 sequences (100000150 bp) in 2.159 CPU sec, 2.269 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 288213, 29, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 554, 1242)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3312)
[M::mem_pestat] mean and std.dev: (686.20, 673.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4347)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 221, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 657)
[M::mem_pestat] mean and std.dev: (243.94, 120.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 826)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (781, 1504, 3164)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7930)
[M::mem_pestat] mean and std.dev: (1859.45, 1464.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10313)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 441, 1101)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2849)
[M::mem_pestat] mean and std.dev: (657.40, 606.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3723)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 709440 sequences (100000156 bp) in 1.440 CPU sec, 1.443 real sec...
[M::mem_process_seqs] Processed 701404 reads in 135.330 CPU sec, 4.302 real sec
[M::mem_process_seqs] Processed 706882 reads in 91.179 CPU sec, 2.894 real sec
sorting block 44, #reads = 1082815 mem = 536877629 peak = 996634624
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 289341, 30, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 248, 527)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1235)
[M::mem_pestat] mean and std.dev: (276.47, 163.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1589)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 212, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 625)
[M::mem_pestat] mean and std.dev: (234.26, 114.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 785)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (314, 874, 1405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3587)
[M::mem_pestat] mean and std.dev: (675.54, 465.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4678)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 280, 541)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1321)
[M::mem_pestat] mean and std.dev: (336.57, 276.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1711)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707168 sequences (100000267 bp) in 2.528 CPU sec, 2.714 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 288982, 26, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 290, 758)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1940)
[M::mem_pestat] mean and std.dev: (382.55, 373.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2531)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 215, 310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 638)
[M::mem_pestat] mean and std.dev: (237.73, 116.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 802)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (531, 1340, 2773)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7257)
[M::mem_pestat] mean and std.dev: (1808.04, 1842.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9499)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 305, 823)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2039)
[M::mem_pestat] mean and std.dev: (465.20, 400.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2647)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 710608 reads in 135.022 CPU sec, 4.289 real sec
[M::process] read 706770 sequences (100000078 bp) in 1.536 CPU sec, 1.556 real sec...
[M::mem_process_seqs] Processed 709440 reads in 90.493 CPU sec, 2.867 real sec
sorting block 45, #reads = 1086438 mem = 536886036 peak = 996634624
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 288283, 30, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 481, 1824)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5058)
[M::mem_pestat] mean and std.dev: (995.14, 1158.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6675)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 221, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653)
[M::mem_pestat] mean and std.dev: (242.99, 119.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 821)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (469, 726, 2299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5959)
[M::mem_pestat] mean and std.dev: (1618.60, 1888.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9173)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 355, 670)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1582)
[M::mem_pestat] mean and std.dev: (440.15, 378.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2038)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 46, #reads = 1088976 mem = 536878020 peak = 996634624
[M::process] read 705892 sequences (100000205 bp) in 2.576 CPU sec, 2.787 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 287892, 34, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 228, 480)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1082)
[M::mem_pestat] mean and std.dev: (359.53, 292.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1529)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 222, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (245.30, 121.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 838)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (46, 610, 1905)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5623)
[M::mem_pestat] mean and std.dev: (1022.68, 1225.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7482)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 423, 1527)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4247)
[M::mem_pestat] mean and std.dev: (868.30, 924.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5607)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707168 reads in 132.828 CPU sec, 4.230 real sec
[M::mem_process_seqs] Processed 706770 reads in 89.564 CPU sec, 2.836 real sec
[M::process] read 706038 sequences (100000064 bp) in 1.644 CPU sec, 1.678 real sec...
sorting block 47, #reads = 1087452 mem = 536881018 peak = 996634624
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 287961, 30, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 458, 1454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3970)
[M::mem_pestat] mean and std.dev: (831.86, 912.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5228)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 223, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667)
[M::mem_pestat] mean and std.dev: (246.21, 121.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 839)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 1117, 1645)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4393)
[M::mem_pestat] mean and std.dev: (1018.27, 859.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5767)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 299, 1176)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3102)
[M::mem_pestat] mean and std.dev: (664.60, 759.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4065)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705756 sequences (100000110 bp) in 1.946 CPU sec, 2.035 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 288236, 25, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 396, 521)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1127)
[M::mem_pestat] mean and std.dev: (347.74, 190.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1430)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 223, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667)
[M::mem_pestat] mean and std.dev: (246.66, 121.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 839)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 709, 2532)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7190)
[M::mem_pestat] mean and std.dev: (1311.12, 1374.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9519)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 397, 877)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2181)
[M::mem_pestat] mean and std.dev: (510.55, 458.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2833)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705396 sequences (100000205 bp) in 1.410 CPU sec, 1.409 real sec...
[M::mem_process_seqs] Processed 705892 reads in 130.235 CPU sec, 4.147 real sec
[M::mem_process_seqs] Processed 706038 reads in 94.825 CPU sec, 3.029 real sec
sorting block 48, #reads = 1086569 mem = 536880158 peak = 996634624
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (94, 287782, 24, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 351, 1088)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2914)
[M::mem_pestat] mean and std.dev: (552.52, 563.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3827)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 225, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (248.96, 123.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 855)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (352, 634, 2039)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5413)
[M::mem_pestat] mean and std.dev: (1018.59, 1047.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7100)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (268, 458, 996)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2452)
[M::mem_pestat] mean and std.dev: (595.76, 525.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3180)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704948 sequences (100000151 bp) in 2.375 CPU sec, 2.568 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 287505, 35, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 457, 1021)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2703)
[M::mem_pestat] mean and std.dev: (612.01, 602.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3544)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 225, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (248.66, 123.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 848)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 508, 1368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3724)
[M::mem_pestat] mean and std.dev: (740.85, 845.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4902)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 360, 1085)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2847)
[M::mem_pestat] mean and std.dev: (531.40, 539.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3728)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705756 reads in 128.831 CPU sec, 4.113 real sec
[M::mem_process_seqs] Processed 705396 reads in 86.792 CPU sec, 2.747 real sec
sorting block 49, #reads = 1087578 mem = 536879149 peak = 996634624
[M::process] read 704680 sequences (100000049 bp) in 2.007 CPU sec, 2.139 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 287831, 35, 84)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 442, 2393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6741)
[M::mem_pestat] mean and std.dev: (1115.29, 1336.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8915)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 227, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 681)
[M::mem_pestat] mean and std.dev: (250.58, 124.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 857)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 320, 2111)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6037)
[M::mem_pestat] mean and std.dev: (1055.49, 1427.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8000)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 334, 1163)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3073)
[M::mem_pestat] mean and std.dev: (640.14, 603.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4028)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704960 sequences (100000094 bp) in 1.779 CPU sec, 1.846 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 287694, 38, 86)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 333, 743)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1875)
[M::mem_pestat] mean and std.dev: (470.44, 408.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2441)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 226, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684)
[M::mem_pestat] mean and std.dev: (251.12, 125.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 861)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 1216, 2231)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6393)
[M::mem_pestat] mean and std.dev: (1608.89, 1707.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8474)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 362, 625)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1435)
[M::mem_pestat] mean and std.dev: (355.89, 209.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1840)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704948 reads in 125.588 CPU sec, 4.018 real sec
sorting block 50, #reads = 1086273 mem = 536879579 peak = 1052655616
[M::mem_process_seqs] Processed 704680 reads in 85.043 CPU sec, 2.691 real sec
[M::process] read 704538 sequences (100000222 bp) in 1.620 CPU sec, 1.663 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (88, 287629, 47, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 322, 1175)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3137)
[M::mem_pestat] mean and std.dev: (615.80, 603.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4118)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 226, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (250.66, 125.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 860)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (275, 707, 2918)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8204)
[M::mem_pestat] mean and std.dev: (1596.98, 1641.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10847)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 465, 1696)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4604)
[M::mem_pestat] mean and std.dev: (891.43, 887.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6058)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 51, #reads = 1086933 mem = 536880433 peak = 1065852928
[M::process] read 704132 sequences (100000100 bp) in 2.479 CPU sec, 2.693 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 287160, 38, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 465, 1050)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2774)
[M::mem_pestat] mean and std.dev: (619.79, 569.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3636)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 228, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (252.19, 125.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 869)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (87, 317, 906)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2544)
[M::mem_pestat] mean and std.dev: (454.67, 536.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3363)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (266, 377, 1251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3221)
[M::mem_pestat] mean and std.dev: (775.13, 888.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4329)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704960 reads in 126.377 CPU sec, 4.033 real sec
[M::mem_process_seqs] Processed 704538 reads in 85.933 CPU sec, 2.722 real sec
[M::process] read 703538 sequences (100000255 bp) in 2.308 CPU sec, 2.500 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 287583, 26, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 284, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 768)
[M::mem_pestat] mean and std.dev: (256.51, 136.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 969)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 229, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (253.53, 126.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (318, 592, 1417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3615)
[M::mem_pestat] mean and std.dev: (801.42, 756.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4714)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 414, 1001)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2589)
[M::mem_pestat] mean and std.dev: (510.57, 431.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3383)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 52, #reads = 1086723 mem = 536878432 peak = 1065852928
[M::process] read 703500 sequences (100000065 bp) in 2.040 CPU sec, 2.118 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 286575, 39, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 400, 903)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2359)
[M::mem_pestat] mean and std.dev: (506.15, 456.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3087)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 230, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (254.79, 127.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 882)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (453, 760, 1548)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3738)
[M::mem_pestat] mean and std.dev: (864.37, 596.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4833)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 349, 706)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1684)
[M::mem_pestat] mean and std.dev: (444.50, 340.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2173)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704132 reads in 125.944 CPU sec, 4.033 real sec
[M::mem_process_seqs] Processed 703538 reads in 86.164 CPU sec, 2.731 real sec
sorting block 53, #reads = 1085350 mem = 536876767 peak = 1065852928
[M::process] read 705266 sequences (100000206 bp) in 2.430 CPU sec, 2.620 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 287638, 27, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 343, 1068)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2766)
[M::mem_pestat] mean and std.dev: (617.08, 619.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3615)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 229, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 694)
[M::mem_pestat] mean and std.dev: (253.86, 126.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 874)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (605, 782, 2064)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4982)
[M::mem_pestat] mean and std.dev: (1334.48, 1251.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6441)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 540, 830)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2048)
[M::mem_pestat] mean and std.dev: (534.09, 404.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2657)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 287986, 27, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 273, 1205)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3303)
[M::mem_pestat] mean and std.dev: (691.60, 830.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4352)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (247.89, 123.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 844)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 464, 1453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3905)
[M::mem_pestat] mean and std.dev: (928.96, 1004.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5131)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 457, 1265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3305)
[M::mem_pestat] mean and std.dev: (672.24, 658.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4325)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703500 reads in 126.628 CPU sec, 4.069 real sec
[M::process] read 703024 sequences (100000064 bp) in 2.363 CPU sec, 2.587 real sec...
[M::mem_process_seqs] Processed 705266 reads in 86.576 CPU sec, 2.756 real sec
sorting block 54, #reads = 1084804 mem = 536880937 peak = 1065852928
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (85, 286976, 32, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 360, 1725)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4717)
[M::mem_pestat] mean and std.dev: (812.28, 929.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6213)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 230, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (254.41, 126.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (365, 825, 1437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3581)
[M::mem_pestat] mean and std.dev: (806.64, 573.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4653)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 387, 673)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1619)
[M::mem_pestat] mean and std.dev: (403.15, 277.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2092)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703018 sequences (100000160 bp) in 2.433 CPU sec, 2.700 real sec...
[M::mem_process_seqs] Processed 703024 reads in 72.309 CPU sec, 2.402 real sec
sorting block 55, #reads = 1086677 mem = 536875975 peak = 1065852928
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (90, 287257, 43, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 274, 407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 847)
[M::mem_pestat] mean and std.dev: (279.86, 158.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1067)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 232, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (255.71, 127.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (613, 1499, 1695)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3859)
[M::mem_pestat] mean and std.dev: (1226.32, 742.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4941)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 391, 697)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1691)
[M::mem_pestat] mean and std.dev: (435.62, 332.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2188)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702222 sequences (100000167 bp) in 2.221 CPU sec, 2.401 real sec...
[M::mem_process_seqs] Processed 703018 reads in 72.263 CPU sec, 2.399 real sec
sorting block 56, #reads = 1084647 mem = 536879555 peak = 1065852928
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 286684, 35, 84)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 321, 1221)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3283)
[M::mem_pestat] mean and std.dev: (751.90, 870.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4314)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 233, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (255.39, 125.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 872)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (411, 531, 1379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3315)
[M::mem_pestat] mean and std.dev: (770.33, 722.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4283)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 322, 838)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2026)
[M::mem_pestat] mean and std.dev: (498.82, 391.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2620)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702060 sequences (100000208 bp) in 2.124 CPU sec, 2.290 real sec...
[M::mem_process_seqs] Processed 702222 reads in 71.752 CPU sec, 2.368 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 287120, 30, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 417, 818)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2108)
[M::mem_pestat] mean and std.dev: (511.10, 458.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2753)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 234, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697)
[M::mem_pestat] mean and std.dev: (256.66, 126.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 877)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (464, 802, 2258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5846)
[M::mem_pestat] mean and std.dev: (976.12, 814.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7640)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 401, 1145)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2941)
[M::mem_pestat] mean and std.dev: (634.51, 651.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3839)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 57, #reads = 1085317 mem = 536878132 peak = 1065852928
[M::process] read 701912 sequences (100000277 bp) in 1.972 CPU sec, 2.128 real sec...
[M::mem_process_seqs] Processed 702060 reads in 72.303 CPU sec, 2.367 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 286425, 35, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 335, 1111)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2939)
[M::mem_pestat] mean and std.dev: (606.46, 647.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3853)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 234, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697)
[M::mem_pestat] mean and std.dev: (256.90, 126.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 877)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (450, 736, 1815)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4545)
[M::mem_pestat] mean and std.dev: (1162.15, 950.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5910)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 393, 715)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1805)
[M::mem_pestat] mean and std.dev: (455.93, 381.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2350)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701368 sequences (100000042 bp) in 2.295 CPU sec, 2.536 real sec...
[M::process] read 701852 sequences (100000135 bp) in 1.269 CPU sec, 1.267 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 286297, 31, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 259, 844)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2224)
[M::mem_pestat] mean and std.dev: (404.75, 430.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2914)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 233, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 694)
[M::mem_pestat] mean and std.dev: (255.95, 125.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 873)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 474, 1082)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2960)
[M::mem_pestat] mean and std.dev: (600.48, 554.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3899)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 437, 825)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2063)
[M::mem_pestat] mean and std.dev: (507.92, 389.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2682)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701368 reads in 69.815 CPU sec, 2.207 real sec
[M::process] read 702124 sequences (100000056 bp) in 1.318 CPU sec, 1.334 real sec...
sorting block 58, #reads = 1084562 mem = 536880073 peak = 1065852928
[M::mem_process_seqs] Processed 701912 reads in 167.437 CPU sec, 5.362 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (79, 286340, 37, 91)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 293, 585)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1419)
[M::mem_pestat] mean and std.dev: (344.69, 301.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1836)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 232, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (254.44, 124.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 861)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 579, 1465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4087)
[M::mem_pestat] mean and std.dev: (811.77, 900.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5398)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 375, 863)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2163)
[M::mem_pestat] mean and std.dev: (512.68, 415.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2813)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 59, #reads = 1083489 mem = 536879399 peak = 1065852928
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 286548, 24, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 329, 825)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2115)
[M::mem_pestat] mean and std.dev: (496.38, 434.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2760)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 231, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (254.52, 125.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (460, 1014, 2078)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5314)
[M::mem_pestat] mean and std.dev: (1185.30, 992.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6932)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 298, 882)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2272)
[M::mem_pestat] mean and std.dev: (433.00, 403.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2967)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702304 sequences (100000067 bp) in 2.670 CPU sec, 2.894 real sec...
[M::mem_process_seqs] Processed 701852 reads in 140.882 CPU sec, 4.481 real sec
[M::mem_process_seqs] Processed 702124 reads in 85.636 CPU sec, 2.718 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 286641, 32, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 299, 832)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2068)
[M::mem_pestat] mean and std.dev: (505.48, 493.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2686)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 231, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 681)
[M::mem_pestat] mean and std.dev: (253.02, 123.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 856)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (587, 1242, 2521)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6389)
[M::mem_pestat] mean and std.dev: (1455.71, 1250.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8323)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 391, 942)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2398)
[M::mem_pestat] mean and std.dev: (553.29, 537.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3126)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702438 sequences (100000110 bp) in 2.528 CPU sec, 2.796 real sec...
sorting block 60, #reads = 1083514 mem = 536893569 peak = 1065852928
[M::mem_process_seqs] Processed 702304 reads in 73.059 CPU sec, 2.404 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 286471, 56, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 324, 508)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1144)
[M::mem_pestat] mean and std.dev: (328.70, 221.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1462)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 230, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (252.83, 124.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 859)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (569, 683, 2025)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4937)
[M::mem_pestat] mean and std.dev: (1117.61, 877.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6393)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 357, 1173)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3135)
[M::mem_pestat] mean and std.dev: (677.10, 703.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4116)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702844 sequences (100000075 bp) in 2.243 CPU sec, 2.493 real sec...
[M::mem_process_seqs] Processed 702438 reads in 73.244 CPU sec, 2.396 real sec
sorting block 61, #reads = 1084167 mem = 536879816 peak = 1065852928
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 286449, 39, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 287, 1023)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2711)
[M::mem_pestat] mean and std.dev: (484.58, 534.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3555)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 229, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (252.53, 124.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 859)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 791, 1297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3501)
[M::mem_pestat] mean and std.dev: (832.92, 686.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4603)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 397, 797)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1987)
[M::mem_pestat] mean and std.dev: (512.11, 416.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2582)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702844 reads in 73.763 CPU sec, 2.417 real sec
[M::process] read 702298 sequences (100000188 bp) in 2.390 CPU sec, 2.660 real sec...
sorting block 62, #reads = 1082805 mem = 536882026 peak = 1065852928
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 286849, 28, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 268, 509)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1155)
[M::mem_pestat] mean and std.dev: (298.62, 179.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1478)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 232, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (254.85, 125.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 578, 1196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3226)
[M::mem_pestat] mean and std.dev: (746.86, 728.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4241)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 313, 972)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2458)
[M::mem_pestat] mean and std.dev: (525.78, 466.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3201)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701430 sequences (100000221 bp) in 1.937 CPU sec, 2.058 real sec...
[M::mem_process_seqs] Processed 702298 reads in 72.296 CPU sec, 2.362 real sec
sorting block 63, #reads = 1083388 mem = 536878201 peak = 1065852928
[M::process] read 701412 sequences (100000199 bp) in 1.733 CPU sec, 1.826 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 286359, 40, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 299, 596)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1394)
[M::mem_pestat] mean and std.dev: (381.84, 279.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1793)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 234, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 694)
[M::mem_pestat] mean and std.dev: (256.01, 125.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 873)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (427, 630, 1321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3109)
[M::mem_pestat] mean and std.dev: (789.33, 508.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4003)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 333, 1348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3636)
[M::mem_pestat] mean and std.dev: (618.29, 636.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4780)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701670 sequences (100000274 bp) in 1.310 CPU sec, 1.303 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 286554, 36, 94)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 218, 484)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1122)
[M::mem_pestat] mean and std.dev: (277.31, 198.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1441)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 234, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697)
[M::mem_pestat] mean and std.dev: (256.43, 125.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 877)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (308, 531, 1375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3509)
[M::mem_pestat] mean and std.dev: (772.94, 727.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4576)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 448, 1503)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4093)
[M::mem_pestat] mean and std.dev: (802.12, 888.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5388)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701132 sequences (100000145 bp) in 1.190 CPU sec, 1.193 real sec...
[M::mem_process_seqs] Processed 701430 reads in 128.169 CPU sec, 4.029 real sec
[M::mem_process_seqs] Processed 701412 reads in 85.987 CPU sec, 2.718 real sec
sorting block 64, #reads = 1082194 mem = 536878019 peak = 1065852928
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 286228, 34, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 457, 1218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3282)
[M::mem_pestat] mean and std.dev: (706.88, 766.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4314)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 234, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (257.09, 126.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 881)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (282, 790, 1148)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2880)
[M::mem_pestat] mean and std.dev: (734.94, 486.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3746)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 340, 1192)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3212)
[M::mem_pestat] mean and std.dev: (627.04, 569.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4222)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701268 sequences (100000033 bp) in 1.884 CPU sec, 1.985 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 286097, 28, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 388, 1268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3364)
[M::mem_pestat] mean and std.dev: (704.18, 722.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4412)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 236, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701)
[M::mem_pestat] mean and std.dev: (258.07, 126.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 882)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (477, 868, 3131)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8439)
[M::mem_pestat] mean and std.dev: (1937.64, 2062.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11093)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 319, 635)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1509)
[M::mem_pestat] mean and std.dev: (451.99, 328.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1946)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705940 sequences (100000003 bp) in 1.410 CPU sec, 1.411 real sec...
[M::mem_process_seqs] Processed 701670 reads in 129.099 CPU sec, 4.108 real sec
[M::mem_process_seqs] Processed 701132 reads in 86.613 CPU sec, 2.751 real sec
sorting block 65, #reads = 1081350 mem = 536881433 peak = 1065852928
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 285932, 36, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 336, 694)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1712)
[M::mem_pestat] mean and std.dev: (405.03, 339.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2221)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 234, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701)
[M::mem_pestat] mean and std.dev: (257.69, 126.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 882)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (283, 655, 1316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3382)
[M::mem_pestat] mean and std.dev: (770.24, 711.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4415)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 338, 581)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1361)
[M::mem_pestat] mean and std.dev: (347.96, 217.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1751)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 711064 sequences (100000185 bp) in 2.039 CPU sec, 2.169 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 287336, 50, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 562, 2185)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6177)
[M::mem_pestat] mean and std.dev: (1107.86, 1313.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8173)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 225, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (249.06, 124.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 855)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (540, 1208, 1977)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4851)
[M::mem_pestat] mean and std.dev: (1174.74, 969.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6288)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 304, 813)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2093)
[M::mem_pestat] mean and std.dev: (440.11, 398.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2733)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 710206 sequences (100000116 bp) in 1.320 CPU sec, 1.324 real sec...
[M::mem_process_seqs] Processed 701268 reads in 133.693 CPU sec, 4.251 real sec
[M::mem_process_seqs] Processed 705940 reads in 92.074 CPU sec, 2.930 real sec
sorting block 66, #reads = 1081686 mem = 536877648 peak = 1065852928
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 289878, 18, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 357, 916)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2294)
[M::mem_pestat] mean and std.dev: (435.89, 347.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2983)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 212, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 625)
[M::mem_pestat] mean and std.dev: (234.17, 115.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 785)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (82, 452, 785)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2191)
[M::mem_pestat] mean and std.dev: (443.24, 355.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2894)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 326, 1177)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3057)
[M::mem_pestat] mean and std.dev: (691.78, 721.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3997)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708000 sequences (100000145 bp) in 1.797 CPU sec, 1.880 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 289387, 27, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 328, 534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1294)
[M::mem_pestat] mean and std.dev: (338.39, 217.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1674)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 212, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 625)
[M::mem_pestat] mean and std.dev: (234.64, 114.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 785)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (494, 1211, 1994)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4994)
[M::mem_pestat] mean and std.dev: (1291.73, 911.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6494)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 369, 958)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2400)
[M::mem_pestat] mean and std.dev: (629.88, 573.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3121)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706674 sequences (100000298 bp) in 1.390 CPU sec, 1.392 real sec...
[M::mem_process_seqs] Processed 711064 reads in 131.246 CPU sec, 4.392 real sec
sorting block 67, #reads = 1080792 mem = 536882454 peak = 1065852928
[M::mem_process_seqs] Processed 710206 reads in 84.135 CPU sec, 2.678 real sec
sorting block 68, #reads = 1090350 mem = 536878590 peak = 1143111680
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 288394, 33, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 413, 864)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2152)
[M::mem_pestat] mean and std.dev: (528.12, 419.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2796)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 219, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 655)
[M::mem_pestat] mean and std.dev: (242.47, 120.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 824)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 591, 1388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3748)
[M::mem_pestat] mean and std.dev: (814.52, 687.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4928)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 322, 1069)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2801)
[M::mem_pestat] mean and std.dev: (603.81, 624.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3667)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706102 sequences (100000013 bp) in 1.907 CPU sec, 1.984 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 287768, 21, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 372, 820)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2068)
[M::mem_pestat] mean and std.dev: (496.70, 445.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2692)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 222, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 660)
[M::mem_pestat] mean and std.dev: (244.95, 121.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 830)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (278, 506, 919)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2201)
[M::mem_pestat] mean and std.dev: (520.45, 346.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2842)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 299, 576)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1292)
[M::mem_pestat] mean and std.dev: (393.04, 273.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1650)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705986 sequences (100000003 bp) in 1.400 CPU sec, 1.399 real sec...
[M::mem_process_seqs] Processed 708000 reads in 125.701 CPU sec, 4.000 real sec
[M::mem_process_seqs] Processed 706674 reads in 84.384 CPU sec, 2.682 real sec
sorting block 69, #reads = 1087900 mem = 536877608 peak = 1143111680
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 288298, 25, 90)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 436, 803)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1943)
[M::mem_pestat] mean and std.dev: (456.73, 289.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2513)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 223, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 670)
[M::mem_pestat] mean and std.dev: (246.94, 122.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 843)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 644, 2765)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8015)
[M::mem_pestat] mean and std.dev: (1408.42, 1603.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10640)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 304, 734)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1778)
[M::mem_pestat] mean and std.dev: (360.99, 302.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2300)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705406 sequences (100000131 bp) in 1.836 CPU sec, 1.913 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 288008, 22, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 355, 885)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2205)
[M::mem_pestat] mean and std.dev: (474.89, 398.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2865)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 224, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 676)
[M::mem_pestat] mean and std.dev: (248.38, 123.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 851)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (285, 689, 822)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1896)
[M::mem_pestat] mean and std.dev: (516.78, 317.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2433)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 392, 1037)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2693)
[M::mem_pestat] mean and std.dev: (487.60, 491.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3521)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706102 reads in 124.556 CPU sec, 3.967 real sec
[M::process] read 705236 sequences (100000075 bp) in 1.400 CPU sec, 1.405 real sec...
[M::mem_process_seqs] Processed 705986 reads in 83.631 CPU sec, 2.653 real sec
sorting block 70, #reads = 1087302 mem = 536879599 peak = 1143111680
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 287654, 41, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 393, 1113)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2959)
[M::mem_pestat] mean and std.dev: (514.75, 463.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3882)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 226, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (249.57, 124.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 856)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (288, 639, 1781)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4767)
[M::mem_pestat] mean and std.dev: (874.18, 794.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6260)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 386, 781)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1885)
[M::mem_pestat] mean and std.dev: (504.61, 397.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2437)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704814 sequences (100000155 bp) in 2.039 CPU sec, 2.127 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 288192, 34, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 277, 1601)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4399)
[M::mem_pestat] mean and std.dev: (923.59, 1160.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5798)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 225, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (250.52, 125.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 860)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 1059, 2100)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5884)
[M::mem_pestat] mean and std.dev: (1336.56, 1256.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7776)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 337, 896)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2388)
[M::mem_pestat] mean and std.dev: (409.16, 369.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3134)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705406 reads in 124.201 CPU sec, 3.947 real sec
[M::process] read 704140 sequences (100000051 bp) in 1.420 CPU sec, 1.417 real sec...
sorting block 71, #reads = 1087318 mem = 536877862 peak = 1143111680
[M::mem_process_seqs] Processed 705236 reads in 84.068 CPU sec, 2.668 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (84, 287448, 25, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 264, 1030)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2758)
[M::mem_pestat] mean and std.dev: (500.69, 535.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3622)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 227, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 681)
[M::mem_pestat] mean and std.dev: (250.69, 124.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 857)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (261, 285, 1760)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4758)
[M::mem_pestat] mean and std.dev: (885.79, 935.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6257)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 388, 1737)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4783)
[M::mem_pestat] mean and std.dev: (779.25, 864.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6306)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 72, #reads = 1087611 mem = 536878079 peak = 1143111680
[M::process] read 703994 sequences (100000228 bp) in 2.205 CPU sec, 2.406 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 287219, 34, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 326, 1007)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2713)
[M::mem_pestat] mean and std.dev: (581.03, 641.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3566)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 228, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (252.93, 126.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 873)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 829, 1005)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2743)
[M::mem_pestat] mean and std.dev: (640.86, 500.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3612)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 287, 580)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1288)
[M::mem_pestat] mean and std.dev: (346.03, 238.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1642)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704814 reads in 124.142 CPU sec, 3.958 real sec
[M::mem_process_seqs] Processed 704140 reads in 84.272 CPU sec, 2.667 real sec
[M::process] read 703760 sequences (100000172 bp) in 1.704 CPU sec, 1.749 real sec...
sorting block 73, #reads = 1086250 mem = 536882929 peak = 1143111680
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 287076, 26, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 376, 1321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3587)
[M::mem_pestat] mean and std.dev: (792.49, 821.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4720)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (252.71, 126.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (446, 903, 2011)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5141)
[M::mem_pestat] mean and std.dev: (1366.24, 1330.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6706)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 432, 595)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1405)
[M::mem_pestat] mean and std.dev: (456.51, 272.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1810)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703498 sequences (100000176 bp) in 1.929 CPU sec, 2.064 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 287084, 29, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 478, 2136)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5938)
[M::mem_pestat] mean and std.dev: (1242.96, 1457.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7839)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 229, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (253.29, 126.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 573, 1507)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4067)
[M::mem_pestat] mean and std.dev: (790.12, 930.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5347)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 274, 1293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3499)
[M::mem_pestat] mean and std.dev: (588.96, 699.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4602)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703994 reads in 126.044 CPU sec, 4.018 real sec
[M::process] read 703306 sequences (100000256 bp) in 1.512 CPU sec, 1.530 real sec...
[M::mem_process_seqs] Processed 703760 reads in 85.223 CPU sec, 2.697 real sec
sorting block 74, #reads = 1086739 mem = 536878327 peak = 1143111680
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 287490, 26, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 263, 936)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2426)
[M::mem_pestat] mean and std.dev: (501.12, 425.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3171)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 230, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697)
[M::mem_pestat] mean and std.dev: (254.51, 127.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 878)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (47, 302, 1527)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4487)
[M::mem_pestat] mean and std.dev: (876.32, 1200.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5967)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 359, 684)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1626)
[M::mem_pestat] mean and std.dev: (439.70, 317.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2097)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703292 sequences (100000123 bp) in 1.880 CPU sec, 1.966 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (84, 287277, 22, 86)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 297, 605)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1479)
[M::mem_pestat] mean and std.dev: (320.55, 248.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1916)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 231, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (255.25, 127.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (130, 516, 771)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2053)
[M::mem_pestat] mean and std.dev: (438.65, 429.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2694)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 254, 971)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2511)
[M::mem_pestat] mean and std.dev: (454.29, 434.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3281)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703498 reads in 125.377 CPU sec, 4.156 real sec
[M::process] read 705204 sequences (100000269 bp) in 1.400 CPU sec, 1.407 real sec...
[M::mem_process_seqs] Processed 703306 reads in 84.274 CPU sec, 2.673 real sec
sorting block 75, #reads = 1086870 mem = 536877851 peak = 1143111680
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 286712, 33, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 458, 1050)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2660)
[M::mem_pestat] mean and std.dev: (514.69, 430.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3465)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 231, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (255.49, 127.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (392, 633, 1119)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2573)
[M::mem_pestat] mean and std.dev: (719.32, 509.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3300)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 293, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 978)
[M::mem_pestat] mean and std.dev: (303.02, 143.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1234)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 76, #reads = 1085221 mem = 536878441 peak = 1143111680
[M::process] read 702872 sequences (100000185 bp) in 2.328 CPU sec, 2.532 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 287764, 36, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 342, 1205)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3131)
[M::mem_pestat] mean and std.dev: (734.97, 820.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4094)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 225, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (248.53, 123.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 848)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (527, 1251, 2191)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5519)
[M::mem_pestat] mean and std.dev: (1192.47, 997.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7183)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 312, 1019)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2665)
[M::mem_pestat] mean and std.dev: (510.39, 486.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3488)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703292 reads in 127.355 CPU sec, 4.065 real sec
[M::mem_process_seqs] Processed 705204 reads in 86.588 CPU sec, 2.744 real sec
[M::process] read 702140 sequences (100000278 bp) in 1.661 CPU sec, 1.714 real sec...
sorting block 77, #reads = 1086121 mem = 536879237 peak = 1143111680
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (87, 286956, 23, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 473, 1312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3462)
[M::mem_pestat] mean and std.dev: (720.13, 664.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4537)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 231, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (255.19, 126.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 875)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (557, 2050, 3530)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9476)
[M::mem_pestat] mean and std.dev: (2388.00, 2220.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12449)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 326, 800)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1978)
[M::mem_pestat] mean and std.dev: (426.46, 336.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2567)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701712 sequences (100000092 bp) in 1.779 CPU sec, 1.856 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 286542, 47, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 288, 715)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1785)
[M::mem_pestat] mean and std.dev: (402.37, 371.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2320)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 233, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 705)
[M::mem_pestat] mean and std.dev: (257.60, 128.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 888)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (364, 1097, 2581)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7015)
[M::mem_pestat] mean and std.dev: (1362.67, 1222.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9232)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (302, 353, 886)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2054)
[M::mem_pestat] mean and std.dev: (420.57, 312.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2638)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702872 reads in 125.881 CPU sec, 4.013 real sec
[M::process] read 701476 sequences (100000259 bp) in 1.503 CPU sec, 1.521 real sec...
[M::mem_process_seqs] Processed 702140 reads in 84.870 CPU sec, 2.687 real sec
sorting block 78, #reads = 1086473 mem = 536883977 peak = 1143111680
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 286551, 22, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 300, 720)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1856)
[M::mem_pestat] mean and std.dev: (440.39, 401.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2424)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 234, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (257.30, 127.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 881)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 464, 810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2002)
[M::mem_pestat] mean and std.dev: (392.67, 312.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2598)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 434, 1170)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3120)
[M::mem_pestat] mean and std.dev: (692.85, 685.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4095)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701056 sequences (100000237 bp) in 2.411 CPU sec, 2.645 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 286771, 29, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 355, 514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1156)
[M::mem_pestat] mean and std.dev: (370.25, 226.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1477)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 234, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (256.21, 125.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (336, 989, 2547)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6969)
[M::mem_pestat] mean and std.dev: (1476.54, 1515.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9180)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 288, 583)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1383)
[M::mem_pestat] mean and std.dev: (315.48, 184.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1783)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701712 reads in 126.998 CPU sec, 4.070 real sec
[M::mem_process_seqs] Processed 701476 reads in 86.570 CPU sec, 2.746 real sec
sorting block 79, #reads = 1085746 mem = 536880748 peak = 1143111680
[M::process] read 700998 sequences (100000192 bp) in 2.425 CPU sec, 2.612 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 286209, 52, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 289, 709)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1745)
[M::mem_pestat] mean and std.dev: (447.49, 399.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2263)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 234, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (256.39, 125.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 728, 1662)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4516)
[M::mem_pestat] mean and std.dev: (997.84, 876.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5943)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 465, 1171)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3089)
[M::mem_pestat] mean and std.dev: (662.47, 675.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4048)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701544 sequences (100000130 bp) in 1.771 CPU sec, 1.851 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 285831, 30, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 384, 1069)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2783)
[M::mem_pestat] mean and std.dev: (594.63, 558.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3640)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 234, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (255.99, 124.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (488, 1237, 1780)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4364)
[M::mem_pestat] mean and std.dev: (1135.24, 775.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5656)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 366, 701)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1617)
[M::mem_pestat] mean and std.dev: (426.81, 297.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2075)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701056 reads in 127.646 CPU sec, 4.087 real sec
sorting block 80, #reads = 1083479 mem = 536879032 peak = 1143111680
[M::process] read 701288 sequences (100000218 bp) in 1.750 CPU sec, 1.827 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 286311, 30, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 482, 1319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3513)
[M::mem_pestat] mean and std.dev: (709.55, 702.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4610)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 232, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (253.95, 123.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 857)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (384, 717, 1997)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5223)
[M::mem_pestat] mean and std.dev: (1276.87, 1204.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6836)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 379, 632)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1496)
[M::mem_pestat] mean and std.dev: (401.43, 269.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1928)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701544 reads in 72.316 CPU sec, 2.289 real sec
[M::process] read 701782 sequences (100000067 bp) in 1.372 CPU sec, 1.379 real sec...
sorting block 81, #reads = 1082726 mem = 536880908 peak = 1145303040
[M::mem_process_seqs] Processed 700998 reads in 190.248 CPU sec, 6.036 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 286667, 23, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 384, 1431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3899)
[M::mem_pestat] mean and std.dev: (774.77, 872.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5133)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 232, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (254.29, 123.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 857)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (465, 657, 1289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2937)
[M::mem_pestat] mean and std.dev: (758.95, 571.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3761)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 396, 926)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2318)
[M::mem_pestat] mean and std.dev: (588.98, 555.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3014)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701276 sequences (100000218 bp) in 2.220 CPU sec, 2.405 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 286179, 55, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 312, 1147)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3009)
[M::mem_pestat] mean and std.dev: (539.73, 588.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3940)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 232, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (254.53, 124.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (322, 718, 1940)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5176)
[M::mem_pestat] mean and std.dev: (1254.55, 1209.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6794)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 382, 1389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3731)
[M::mem_pestat] mean and std.dev: (730.55, 773.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4902)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701288 reads in 143.040 CPU sec, 4.543 real sec
sorting block 82, #reads = 1082785 mem = 536879496 peak = 1145303040
[M::mem_process_seqs] Processed 701782 reads in 87.038 CPU sec, 2.760 real sec
[M::process] read 701660 sequences (100000280 bp) in 1.832 CPU sec, 1.909 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 285895, 20, 89)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 340, 1107)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2847)
[M::mem_pestat] mean and std.dev: (670.87, 680.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3717)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 233, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (254.96, 124.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 865)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 508, 1779)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4999)
[M::mem_pestat] mean and std.dev: (1045.25, 1264.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6609)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (274, 477, 880)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2092)
[M::mem_pestat] mean and std.dev: (540.58, 400.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2698)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 83, #reads = 1082126 mem = 536876998 peak = 1160380416
[M::process] read 701228 sequences (100000035 bp) in 2.097 CPU sec, 2.297 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 286929, 41, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 291, 1182)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3218)
[M::mem_pestat] mean and std.dev: (547.74, 627.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4236)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 233, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (255.53, 124.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 869)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (333, 597, 962)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2220)
[M::mem_pestat] mean and std.dev: (637.00, 507.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2849)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 354, 630)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1456)
[M::mem_pestat] mean and std.dev: (416.39, 320.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1869)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701276 reads in 128.378 CPU sec, 4.098 real sec
[M::mem_process_seqs] Processed 701660 reads in 86.890 CPU sec, 2.752 real sec
[M::process] read 701046 sequences (100000129 bp) in 2.075 CPU sec, 2.210 real sec...
sorting block 84, #reads = 1083041 mem = 536880451 peak = 1160380416
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 285988, 41, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 369, 828)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2076)
[M::mem_pestat] mean and std.dev: (592.42, 491.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2700)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 233, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (255.36, 124.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 869)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (350, 762, 1417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3551)
[M::mem_pestat] mean and std.dev: (763.44, 636.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4618)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 374, 1145)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2995)
[M::mem_pestat] mean and std.dev: (647.62, 591.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3920)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 286258, 35, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 327, 770)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1894)
[M::mem_pestat] mean and std.dev: (554.61, 477.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2465)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 701358 sequences (100000000 bp) in 2.324 CPU sec, 2.493 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (158, 234, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (256.38, 125.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (736, 1318, 2389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5695)
[M::mem_pestat] mean and std.dev: (1235.97, 817.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7348)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 346, 709)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1671)
[M::mem_pestat] mean and std.dev: (408.47, 273.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2152)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701228 reads in 128.030 CPU sec, 4.098 real sec
[M::mem_process_seqs] Processed 701046 reads in 87.194 CPU sec, 2.770 real sec
sorting block 85, #reads = 1083132 mem = 536879565 peak = 1160380416
[M::process] read 701140 sequences (100000045 bp) in 1.904 CPU sec, 1.992 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 286077, 45, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 256, 760)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1956)
[M::mem_pestat] mean and std.dev: (423.65, 401.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2554)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 234, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (257.12, 126.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 878)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (683, 1220, 2035)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4739)
[M::mem_pestat] mean and std.dev: (1340.95, 1093.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6091)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 432, 954)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2414)
[M::mem_pestat] mean and std.dev: (551.95, 492.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3144)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701090 sequences (100000144 bp) in 1.841 CPU sec, 1.943 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 285871, 38, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 395, 1365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3753)
[M::mem_pestat] mean and std.dev: (783.36, 886.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4947)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (257.65, 126.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 878)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (344, 948, 2058)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5486)
[M::mem_pestat] mean and std.dev: (1224.03, 1237.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7200)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 405, 1071)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2791)
[M::mem_pestat] mean and std.dev: (642.46, 614.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3651)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701358 reads in 129.535 CPU sec, 4.128 real sec
sorting block 86, #reads = 1082423 mem = 536879796 peak = 1160380416
[M::mem_process_seqs] Processed 701140 reads in 86.973 CPU sec, 2.750 real sec
[M::process] read 700844 sequences (100000299 bp) in 1.839 CPU sec, 1.909 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 286394, 43, 106)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 334, 524)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1212)
[M::mem_pestat] mean and std.dev: (311.02, 199.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1556)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701)
[M::mem_pestat] mean and std.dev: (258.30, 127.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 882)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 497, 2309)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6501)
[M::mem_pestat] mean and std.dev: (1182.20, 1385.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8597)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 362, 739)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1821)
[M::mem_pestat] mean and std.dev: (458.11, 428.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2362)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 87, #reads = 1082675 mem = 536879571 peak = 1160380416
[M::process] read 701144 sequences (100000238 bp) in 2.233 CPU sec, 2.317 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 286236, 26, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (283, 405, 1264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3226)
[M::mem_pestat] mean and std.dev: (651.41, 589.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4207)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 236, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 704)
[M::mem_pestat] mean and std.dev: (258.73, 127.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 886)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (599, 923, 1522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3368)
[M::mem_pestat] mean and std.dev: (739.85, 501.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4291)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 336, 622)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1438)
[M::mem_pestat] mean and std.dev: (346.28, 217.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1846)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701090 reads in 127.714 CPU sec, 4.067 real sec
[M::mem_process_seqs] Processed 700844 reads in 86.810 CPU sec, 2.747 real sec
[M::process] read 713666 sequences (100000188 bp) in 2.075 CPU sec, 2.172 real sec...
sorting block 88, #reads = 1081782 mem = 536876012 peak = 1160380416
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 286427, 31, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 299, 1846)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5144)
[M::mem_pestat] mean and std.dev: (1008.03, 1276.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6793)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701)
[M::mem_pestat] mean and std.dev: (258.02, 127.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 882)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (569, 805, 1215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2507)
[M::mem_pestat] mean and std.dev: (966.69, 648.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3561)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 374, 847)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2063)
[M::mem_pestat] mean and std.dev: (464.15, 403.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2671)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 713150 sequences (100000274 bp) in 2.151 CPU sec, 2.318 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 290310, 31, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 260, 503)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1177)
[M::mem_pestat] mean and std.dev: (300.76, 190.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1514)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 205, 294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 598)
[M::mem_pestat] mean and std.dev: (227.19, 111.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 750)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (395, 791, 1252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2966)
[M::mem_pestat] mean and std.dev: (826.87, 535.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3823)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 327, 844)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2144)
[M::mem_pestat] mean and std.dev: (448.44, 456.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2794)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701144 reads in 136.731 CPU sec, 4.365 real sec
[M::mem_process_seqs] Processed 713666 reads in 97.022 CPU sec, 3.066 real sec
[M::process] read 711500 sequences (100000113 bp) in 1.943 CPU sec, 2.034 real sec...
sorting block 89, #reads = 1080080 mem = 536878716 peak = 1160380416
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 290297, 27, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 326, 1212)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3302)
[M::mem_pestat] mean and std.dev: (642.59, 753.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4347)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 206, 296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 604)
[M::mem_pestat] mean and std.dev: (228.62, 112.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 758)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (298, 713, 1955)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5269)
[M::mem_pestat] mean and std.dev: (1071.96, 1092.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6926)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 319, 1442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3940)
[M::mem_pestat] mean and std.dev: (640.02, 726.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5189)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 711546 sequences (100000071 bp) in 2.423 CPU sec, 2.611 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 290079, 32, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 391, 763)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1799)
[M::mem_pestat] mean and std.dev: (460.50, 320.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2317)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 209, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 621)
[M::mem_pestat] mean and std.dev: (232.94, 115.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 780)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (359, 598, 1198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2876)
[M::mem_pestat] mean and std.dev: (639.14, 432.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3715)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 299, 582)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1434)
[M::mem_pestat] mean and std.dev: (348.13, 299.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1860)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 713150 reads in 138.079 CPU sec, 4.402 real sec
[M::mem_process_seqs] Processed 711500 reads in 91.936 CPU sec, 2.907 real sec
sorting block 90, #reads = 1083329 mem = 536885599 peak = 1160380416
[M::process] read 711362 sequences (100000191 bp) in 1.966 CPU sec, 2.078 real sec...
sorting block 91, #reads = 1085761 mem = 536877265 peak = 1160380416
[M::process] read 710350 sequences (100000024 bp) in 2.384 CPU sec, 2.585 real sec...
[M::process] read 709408 sequences (100000284 bp) in 1.438 CPU sec, 1.441 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 289812, 33, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 309, 875)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2167)
[M::mem_pestat] mean and std.dev: (502.82, 415.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2813)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 213, 310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 640)
[M::mem_pestat] mean and std.dev: (237.60, 118.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 805)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (361, 920, 2409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6505)
[M::mem_pestat] mean and std.dev: (1466.42, 1486.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8553)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 428, 1027)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2639)
[M::mem_pestat] mean and std.dev: (702.74, 647.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3445)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 710350 reads in 71.728 CPU sec, 2.541 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 290609, 28, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 368, 944)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2558)
[M::mem_pestat] mean and std.dev: (540.59, 584.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3365)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 210, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 633)
[M::mem_pestat] mean and std.dev: (235.11, 117.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 796)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 752, 1426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3906)
[M::mem_pestat] mean and std.dev: (704.12, 625.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5146)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 374, 1305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3453)
[M::mem_pestat] mean and std.dev: (691.70, 725.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4527)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 711362 reads in 145.947 CPU sec, 5.510 real sec
sorting block 92, #reads = 1087262 mem = 536879071 peak = 1160380416
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 289515, 36, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 274, 781)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1943)
[M::mem_pestat] mean and std.dev: (482.35, 412.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2524)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 215, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 647)
[M::mem_pestat] mean and std.dev: (239.43, 119.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 814)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (391, 635, 1071)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2431)
[M::mem_pestat] mean and std.dev: (746.20, 465.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3111)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 518, 1224)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3246)
[M::mem_pestat] mean and std.dev: (712.65, 698.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4257)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 290768, 33, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 284, 688)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1740)
[M::mem_pestat] mean and std.dev: (431.42, 356.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2266)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 210, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 630)
[M::mem_pestat] mean and std.dev: (234.85, 117.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 792)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (54, 784, 2043)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6021)
[M::mem_pestat] mean and std.dev: (1047.61, 1086.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8010)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 287, 933)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2393)
[M::mem_pestat] mean and std.dev: (479.09, 452.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3123)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708522 sequences (100000170 bp) in 2.620 CPU sec, 2.851 real sec...
[M::mem_process_seqs] Processed 709408 reads in 90.670 CPU sec, 2.967 real sec
[M::mem_process_seqs] Processed 711546 reads in 295.999 CPU sec, 10.380 real sec
sorting block 93, #reads = 1088079 mem = 536880772 peak = 1160380416
[M::process] read 708400 sequences (100000115 bp) in 2.016 CPU sec, 2.124 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 289290, 23, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 312, 767)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1871)
[M::mem_pestat] mean and std.dev: (380.08, 301.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2423)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 217, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 655)
[M::mem_pestat] mean and std.dev: (242.17, 121.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 824)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (118, 378, 1320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3724)
[M::mem_pestat] mean and std.dev: (761.23, 812.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4926)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 264, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1005)
[M::mem_pestat] mean and std.dev: (313.92, 194.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1278)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 289918, 32, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 245, 509)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1173)
[M::mem_pestat] mean and std.dev: (273.41, 151.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1505)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 218, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (243.92, 122.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 836)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (515, 1356, 1875)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4595)
[M::mem_pestat] mean and std.dev: (1244.90, 1102.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5955)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 275, 389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 815)
[M::mem_pestat] mean and std.dev: (271.07, 129.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1028)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707864 sequences (100000144 bp) in 2.124 CPU sec, 2.301 real sec...
[M::mem_process_seqs] Processed 708522 reads in 129.956 CPU sec, 4.146 real sec
[M::mem_process_seqs] Processed 708400 reads in 87.301 CPU sec, 2.764 real sec
sorting block 94, #reads = 1088221 mem = 536889071 peak = 1160380416
[M::process] read 707630 sequences (100000018 bp) in 1.964 CPU sec, 2.091 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (87, 288714, 41, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 355, 671)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1587)
[M::mem_pestat] mean and std.dev: (435.32, 314.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2045)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 219, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667)
[M::mem_pestat] mean and std.dev: (244.64, 122.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 840)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (304, 1025, 1695)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4477)
[M::mem_pestat] mean and std.dev: (936.00, 701.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5868)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 519, 1916)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5364)
[M::mem_pestat] mean and std.dev: (1059.46, 1201.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7088)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 95, #reads = 1087549 mem = 536879288 peak = 1160380416
[M::process] read 707332 sequences (100000220 bp) in 1.827 CPU sec, 1.891 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 288882, 32, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 287, 914)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2402)
[M::mem_pestat] mean and std.dev: (516.06, 523.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3146)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 220, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (245.48, 123.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 841)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (267, 715, 1196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3054)
[M::mem_pestat] mean and std.dev: (719.63, 584.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3983)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (269, 479, 1260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3242)
[M::mem_pestat] mean and std.dev: (645.30, 712.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4233)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707864 reads in 130.430 CPU sec, 4.163 real sec
[M::mem_process_seqs] Processed 707630 reads in 86.931 CPU sec, 2.752 real sec
[M::process] read 707152 sequences (100000085 bp) in 1.905 CPU sec, 1.997 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 289290, 34, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 321, 890)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2316)
[M::mem_pestat] mean and std.dev: (482.15, 443.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3029)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 220, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (246.04, 124.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 845)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (523, 894, 1739)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4171)
[M::mem_pestat] mean and std.dev: (1185.91, 1033.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5387)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 415, 1171)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3059)
[M::mem_pestat] mean and std.dev: (718.88, 714.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4003)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 96, #reads = 1086286 mem = 536879334 peak = 1160380416
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 288600, 33, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 264, 688)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1710)
[M::mem_pestat] mean and std.dev: (333.94, 263.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2221)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 221, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (245.98, 123.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 841)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 576, 1064)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2662)
[M::mem_pestat] mean and std.dev: (626.16, 541.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3461)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 317, 964)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2436)
[M::mem_pestat] mean and std.dev: (595.94, 584.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3172)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706406 sequences (100000014 bp) in 2.460 CPU sec, 2.674 real sec...
[M::mem_process_seqs] Processed 707332 reads in 128.271 CPU sec, 4.108 real sec
[M::mem_process_seqs] Processed 707152 reads in 86.352 CPU sec, 2.743 real sec
[M::process] read 707664 sequences (100000161 bp) in 1.808 CPU sec, 1.891 real sec...
sorting block 97, #reads = 1086463 mem = 536878173 peak = 1160380416
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 289094, 26, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 406, 1565)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4225)
[M::mem_pestat] mean and std.dev: (944.19, 1076.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5555)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 223, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 675)
[M::mem_pestat] mean and std.dev: (247.45, 123.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 850)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (329, 935, 1135)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2747)
[M::mem_pestat] mean and std.dev: (842.58, 681.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3570)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 347, 778)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1886)
[M::mem_pestat] mean and std.dev: (521.47, 454.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2440)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706874 sequences (100000216 bp) in 2.246 CPU sec, 2.439 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 288850, 39, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 281, 1235)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3253)
[M::mem_pestat] mean and std.dev: (740.81, 810.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4262)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 219, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (245.24, 123.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 841)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (735, 1337, 2150)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4980)
[M::mem_pestat] mean and std.dev: (1347.00, 928.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6395)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 416, 1402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3798)
[M::mem_pestat] mean and std.dev: (762.33, 709.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4996)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706406 reads in 130.400 CPU sec, 4.159 real sec
[M::mem_process_seqs] Processed 707664 reads in 88.517 CPU sec, 2.805 real sec
sorting block 98, #reads = 1086883 mem = 536879072 peak = 1160380416
[M::process] read 706680 sequences (100000043 bp) in 1.735 CPU sec, 1.786 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 288479, 53, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 756, 2505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7127)
[M::mem_pestat] mean and std.dev: (1617.47, 1989.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9576)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 221, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (246.62, 124.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 845)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (101, 438, 979)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2735)
[M::mem_pestat] mean and std.dev: (616.47, 644.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3613)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (275, 556, 1498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3944)
[M::mem_pestat] mean and std.dev: (887.09, 944.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5167)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706710 sequences (100000162 bp) in 1.804 CPU sec, 1.882 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 288309, 34, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 325, 694)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1772)
[M::mem_pestat] mean and std.dev: (416.32, 356.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2311)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 221, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 675)
[M::mem_pestat] mean and std.dev: (247.44, 124.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 850)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (462, 566, 1154)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2538)
[M::mem_pestat] mean and std.dev: (691.63, 613.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3230)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 300, 841)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2169)
[M::mem_pestat] mean and std.dev: (465.81, 493.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2833)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706462 sequences (100000253 bp) in 1.330 CPU sec, 1.330 real sec...
[M::mem_process_seqs] Processed 706874 reads in 131.344 CPU sec, 4.183 real sec
sorting block 99, #reads = 1086493 mem = 536880329 peak = 1184526336
[M::mem_process_seqs] Processed 706680 reads in 89.055 CPU sec, 2.828 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 288786, 23, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 292, 616)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1522)
[M::mem_pestat] mean and std.dev: (374.44, 288.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1975)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 222, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 675)
[M::mem_pestat] mean and std.dev: (247.74, 124.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 850)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (539, 975, 3555)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9587)
[M::mem_pestat] mean and std.dev: (1794.43, 1591.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12603)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 257, 861)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2197)
[M::mem_pestat] mean and std.dev: (516.71, 453.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2865)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 100, #reads = 1086400 mem = 536881480 peak = 1184731136
[M::process] read 706842 sequences (100000221 bp) in 2.361 CPU sec, 2.566 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 288380, 37, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 287, 631)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1627)
[M::mem_pestat] mean and std.dev: (318.80, 264.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2125)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 222, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 675)
[M::mem_pestat] mean and std.dev: (247.68, 124.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 850)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 523, 1129)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2859)
[M::mem_pestat] mean and std.dev: (560.91, 408.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3724)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 350, 717)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1727)
[M::mem_pestat] mean and std.dev: (429.07, 309.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2232)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706710 reads in 130.863 CPU sec, 4.169 real sec
[M::mem_process_seqs] Processed 706462 reads in 88.456 CPU sec, 2.794 real sec
[M::process] read 706108 sequences (100000175 bp) in 1.881 CPU sec, 1.978 real sec...
sorting block 101, #reads = 1085120 mem = 536879904 peak = 1184731136
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 288720, 30, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 247, 490)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1056)
[M::mem_pestat] mean and std.dev: (303.90, 179.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1339)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 221, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 669)
[M::mem_pestat] mean and std.dev: (246.75, 123.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 842)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 558, 1095)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2839)
[M::mem_pestat] mean and std.dev: (611.15, 527.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3711)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (263, 707, 1408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3698)
[M::mem_pestat] mean and std.dev: (917.55, 914.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4843)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706154 sequences (100000050 bp) in 2.218 CPU sec, 2.416 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 288314, 29, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 325, 676)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1590)
[M::mem_pestat] mean and std.dev: (429.39, 332.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2047)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 223, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 681)
[M::mem_pestat] mean and std.dev: (248.70, 125.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (377, 1220, 2360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6326)
[M::mem_pestat] mean and std.dev: (1478.34, 1297.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8309)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 247, 502)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1132)
[M::mem_pestat] mean and std.dev: (344.56, 261.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1447)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706842 reads in 129.553 CPU sec, 4.140 real sec
[M::mem_process_seqs] Processed 706108 reads in 87.642 CPU sec, 2.775 real sec
sorting block 102, #reads = 1085325 mem = 536877881 peak = 1184731136
[M::process] read 705450 sequences (100000084 bp) in 2.164 CPU sec, 2.318 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 288581, 25, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 418, 874)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2160)
[M::mem_pestat] mean and std.dev: (440.65, 306.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2803)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 223, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (248.73, 124.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 855)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 1501, 6307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 18609)
[M::mem_pestat] mean and std.dev: (2906.48, 3397.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 24760)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 286, 771)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2025)
[M::mem_pestat] mean and std.dev: (451.05, 465.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2652)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705134 sequences (100000229 bp) in 2.008 CPU sec, 2.088 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 288238, 30, 86)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 560, 2338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6580)
[M::mem_pestat] mean and std.dev: (1294.51, 1405.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8701)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 224, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (249.33, 124.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 855)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (322, 948, 2453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6715)
[M::mem_pestat] mean and std.dev: (1374.13, 1235.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8846)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 426, 1739)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4789)
[M::mem_pestat] mean and std.dev: (897.44, 1149.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6314)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706154 reads in 130.925 CPU sec, 4.190 real sec
sorting block 103, #reads = 1084966 mem = 536878839 peak = 1184731136
[M::mem_process_seqs] Processed 705450 reads in 88.827 CPU sec, 2.814 real sec
[M::process] read 704260 sequences (100000008 bp) in 2.166 CPU sec, 2.340 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 288117, 23, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 263, 899)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2359)
[M::mem_pestat] mean and std.dev: (486.41, 561.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3089)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 225, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (249.94, 124.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 856)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (360, 767, 968)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2184)
[M::mem_pestat] mean and std.dev: (689.45, 409.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2792)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 258, 676)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1676)
[M::mem_pestat] mean and std.dev: (384.04, 318.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2176)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 104, #reads = 1085456 mem = 536877845 peak = 1184731136
[M::process] read 703678 sequences (100000110 bp) in 2.394 CPU sec, 2.578 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 287148, 23, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 312, 610)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1494)
[M::mem_pestat] mean and std.dev: (434.00, 410.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2075)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 227, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 681)
[M::mem_pestat] mean and std.dev: (250.73, 124.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 857)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (468, 618, 2226)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5742)
[M::mem_pestat] mean and std.dev: (1387.52, 1227.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7500)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 389, 747)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1823)
[M::mem_pestat] mean and std.dev: (486.87, 372.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2361)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705134 reads in 134.935 CPU sec, 4.315 real sec
[M::mem_process_seqs] Processed 704260 reads in 91.405 CPU sec, 2.898 real sec
[M::process] read 703814 sequences (100000215 bp) in 2.261 CPU sec, 2.443 real sec...
sorting block 105, #reads = 1084373 mem = 536877440 peak = 1184731136
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 286421, 31, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (262, 433, 1673)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4495)
[M::mem_pestat] mean and std.dev: (750.25, 817.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5906)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 229, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (251.96, 124.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (590, 1153, 3351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8873)
[M::mem_pestat] mean and std.dev: (1874.77, 1829.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11634)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 452, 1411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3843)
[M::mem_pestat] mean and std.dev: (645.54, 619.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5059)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703140 sequences (100000080 bp) in 2.030 CPU sec, 2.097 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 287862, 21, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 311, 1203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3229)
[M::mem_pestat] mean and std.dev: (546.76, 546.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4242)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (251.56, 124.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 689, 1544)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4196)
[M::mem_pestat] mean and std.dev: (842.43, 833.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5522)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 331, 661)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1489)
[M::mem_pestat] mean and std.dev: (412.50, 336.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1903)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703678 reads in 134.269 CPU sec, 4.287 real sec
[M::mem_process_seqs] Processed 703814 reads in 91.316 CPU sec, 2.889 real sec
sorting block 106, #reads = 1081151 mem = 536879477 peak = 1184731136
[M::process] read 702928 sequences (100000030 bp) in 2.361 CPU sec, 2.483 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (81, 286557, 31, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 355, 721)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1777)
[M::mem_pestat] mean and std.dev: (430.17, 387.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2305)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 230, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (253.75, 125.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 867)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (122, 432, 1690)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4826)
[M::mem_pestat] mean and std.dev: (894.83, 1102.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6394)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 278, 902)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2392)
[M::mem_pestat] mean and std.dev: (469.10, 495.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3137)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 287077, 32, 97)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 316, 848)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2160)
[M::mem_pestat] mean and std.dev: (501.91, 480.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2816)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 230, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (254.15, 125.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (619, 1070, 2277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5593)
[M::mem_pestat] mean and std.dev: (1397.66, 1081.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7251)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 328, 1634)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4442)
[M::mem_pestat] mean and std.dev: (826.60, 873.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5846)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702692 sequences (100000150 bp) in 2.658 CPU sec, 2.881 real sec...
[M::mem_process_seqs] Processed 703140 reads in 133.669 CPU sec, 4.279 real sec
[M::mem_process_seqs] Processed 702928 reads in 90.981 CPU sec, 2.883 real sec
sorting block 107, #reads = 1082652 mem = 536880745 peak = 1184731136
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 286800, 26, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 491, 888)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2216)
[M::mem_pestat] mean and std.dev: (497.46, 369.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2880)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 231, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (254.70, 125.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (335, 775, 1031)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2423)
[M::mem_pestat] mean and std.dev: (708.25, 465.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3119)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 304, 1472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3940)
[M::mem_pestat] mean and std.dev: (818.28, 856.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5174)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703044 sequences (100000045 bp) in 2.784 CPU sec, 3.071 real sec...
[M::mem_process_seqs] Processed 702692 reads in 76.025 CPU sec, 2.504 real sec
sorting block 108, #reads = 1080848 mem = 536878808 peak = 1184731136
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 286648, 45, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 249, 424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 900)
[M::mem_pestat] mean and std.dev: (277.88, 169.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1138)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 230, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (254.52, 126.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (262, 919, 1973)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5395)
[M::mem_pestat] mean and std.dev: (1051.45, 969.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7106)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 375, 791)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1991)
[M::mem_pestat] mean and std.dev: (468.14, 393.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2591)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702692 sequences (100000030 bp) in 2.238 CPU sec, 2.422 real sec...
[M::mem_process_seqs] Processed 703044 reads in 77.163 CPU sec, 2.533 real sec
sorting block 109, #reads = 1081101 mem = 536881708 peak = 1184731136
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 286724, 26, 92)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 394, 1201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3243)
[M::mem_pestat] mean and std.dev: (670.38, 724.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4264)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 230, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (254.15, 125.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (460, 2465, 2878)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7714)
[M::mem_pestat] mean and std.dev: (1795.00, 1369.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10132)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 427, 956)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2430)
[M::mem_pestat] mean and std.dev: (498.59, 429.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3167)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703660 sequences (100000224 bp) in 2.057 CPU sec, 2.199 real sec...
[M::mem_process_seqs] Processed 702692 reads in 78.432 CPU sec, 2.551 real sec
sorting block 110, #reads = 1079972 mem = 536879276 peak = 1184731136
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 287056, 38, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 349, 891)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2239)
[M::mem_pestat] mean and std.dev: (498.73, 441.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2913)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (252.06, 125.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 862)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (269, 855, 1991)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5435)
[M::mem_pestat] mean and std.dev: (1156.65, 1129.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7157)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 316, 783)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2045)
[M::mem_pestat] mean and std.dev: (440.19, 403.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2676)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717260 sequences (100000252 bp) in 2.331 CPU sec, 2.509 real sec...
[M::mem_process_seqs] Processed 703660 reads in 78.524 CPU sec, 2.524 real sec
[M::process] read 718694 sequences (100000196 bp) in 2.144 CPU sec, 2.255 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 291015, 32, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 304, 908)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2370)
[M::mem_pestat] mean and std.dev: (574.00, 596.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3101)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 199, 284)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 576)
[M::mem_pestat] mean and std.dev: (219.99, 106.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 722)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (371, 629, 1300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3158)
[M::mem_pestat] mean and std.dev: (642.81, 459.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4087)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 285, 979)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2595)
[M::mem_pestat] mean and std.dev: (505.29, 497.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3403)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717672 sequences (100000115 bp) in 1.450 CPU sec, 1.453 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 291638, 30, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 392, 1005)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2639)
[M::mem_pestat] mean and std.dev: (501.10, 460.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3456)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 196, 279)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 563)
[M::mem_pestat] mean and std.dev: (216.64, 103.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 705)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (530, 1377, 2128)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5324)
[M::mem_pestat] mean and std.dev: (1403.93, 1094.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6922)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 369, 737)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1835)
[M::mem_pestat] mean and std.dev: (489.31, 470.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2384)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 716080 sequences (100000274 bp) in 1.310 CPU sec, 1.305 real sec...
[M::mem_process_seqs] Processed 717260 reads in 159.907 CPU sec, 5.043 real sec
sorting block 111, #reads = 1081046 mem = 536881108 peak = 1184731136
[M::mem_process_seqs] Processed 718694 reads in 109.447 CPU sec, 3.475 real sec
sorting block 112, #reads = 1077105 mem = 536877723 peak = 1189416960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 291634, 41, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 333, 643)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1613)
[M::mem_pestat] mean and std.dev: (389.54, 331.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2098)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 199, 286)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 582)
[M::mem_pestat] mean and std.dev: (221.14, 108.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 730)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (431, 854, 1836)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4646)
[M::mem_pestat] mean and std.dev: (1093.34, 1003.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6051)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 386, 1388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3800)
[M::mem_pestat] mean and std.dev: (893.05, 975.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5006)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 715318 sequences (100000058 bp) in 2.259 CPU sec, 2.364 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 291378, 19, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (279, 366, 874)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2064)
[M::mem_pestat] mean and std.dev: (559.35, 495.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2659)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 201, 290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 592)
[M::mem_pestat] mean and std.dev: (224.38, 110.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 743)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (537, 935, 1813)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4365)
[M::mem_pestat] mean and std.dev: (1038.22, 717.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5641)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 399, 1187)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3169)
[M::mem_pestat] mean and std.dev: (576.32, 608.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4160)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 714330 sequences (100000099 bp) in 1.640 CPU sec, 1.638 real sec...
[M::mem_process_seqs] Processed 717672 reads in 156.458 CPU sec, 4.974 real sec
[M::mem_process_seqs] Processed 716080 reads in 104.031 CPU sec, 3.307 real sec
sorting block 113, #reads = 1079109 mem = 536882819 peak = 1189416960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 291220, 38, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 330, 730)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1792)
[M::mem_pestat] mean and std.dev: (418.30, 339.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2323)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (140, 202, 293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 599)
[M::mem_pestat] mean and std.dev: (225.82, 111.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 752)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (341, 692, 1739)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4535)
[M::mem_pestat] mean and std.dev: (969.22, 806.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5933)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 345, 1127)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2963)
[M::mem_pestat] mean and std.dev: (486.85, 548.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3881)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 713054 sequences (100000007 bp) in 1.975 CPU sec, 2.033 real sec...
[M::process] read 711336 sequences (100000009 bp) in 1.440 CPU sec, 1.431 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 291455, 27, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 224, 423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 917)
[M::mem_pestat] mean and std.dev: (245.57, 146.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1164)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (141, 204, 296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 606)
[M::mem_pestat] mean and std.dev: (228.22, 112.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 761)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (322, 501, 1402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3562)
[M::mem_pestat] mean and std.dev: (605.04, 609.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4642)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 376, 764)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1958)
[M::mem_pestat] mean and std.dev: (459.10, 411.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2555)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 715318 reads in 152.932 CPU sec, 4.904 real sec
[M::mem_process_seqs] Processed 714330 reads in 98.741 CPU sec, 3.151 real sec
sorting block 114, #reads = 1080816 mem = 536881927 peak = 1189416960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 290850, 30, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 231, 505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1207)
[M::mem_pestat] mean and std.dev: (255.49, 144.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1558)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 207, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 616)
[M::mem_pestat] mean and std.dev: (230.89, 114.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 774)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (447, 981, 1629)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3993)
[M::mem_pestat] mean and std.dev: (998.72, 844.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5175)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 301, 486)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1104)
[M::mem_pestat] mean and std.dev: (328.72, 201.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1413)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 711588 sequences (100000076 bp) in 2.278 CPU sec, 2.424 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 290380, 24, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 323, 550)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1356)
[M::mem_pestat] mean and std.dev: (337.02, 268.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1759)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 211, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 628)
[M::mem_pestat] mean and std.dev: (235.15, 116.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 789)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 277, 821)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2057)
[M::mem_pestat] mean and std.dev: (525.91, 568.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2802)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 277, 811)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2091)
[M::mem_pestat] mean and std.dev: (422.53, 322.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2731)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 710122 sequences (100000196 bp) in 1.480 CPU sec, 1.473 real sec...
[M::mem_process_seqs] Processed 713054 reads in 154.231 CPU sec, 4.985 real sec
sorting block 115, #reads = 1081223 mem = 536880123 peak = 1189416960
[M::mem_process_seqs] Processed 711336 reads in 100.371 CPU sec, 3.202 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 290654, 22, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 416, 1637)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4521)
[M::mem_pestat] mean and std.dev: (916.89, 986.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5963)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 210, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 627)
[M::mem_pestat] mean and std.dev: (234.51, 116.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 788)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (393, 681, 1109)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2541)
[M::mem_pestat] mean and std.dev: (723.53, 628.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3257)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 314, 775)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1933)
[M::mem_pestat] mean and std.dev: (408.24, 340.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2512)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 116, #reads = 1081188 mem = 536877266 peak = 1190023168
[M::process] read 709330 sequences (100000138 bp) in 2.264 CPU sec, 2.396 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 289682, 22, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 251, 790)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2092)
[M::mem_pestat] mean and std.dev: (483.79, 498.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2743)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 213, 310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 638)
[M::mem_pestat] mean and std.dev: (237.70, 118.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 802)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (438, 943, 1646)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4062)
[M::mem_pestat] mean and std.dev: (1036.24, 817.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5270)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 299, 741)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1853)
[M::mem_pestat] mean and std.dev: (301.12, 203.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2409)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 709368 sequences (100000007 bp) in 1.630 CPU sec, 1.635 real sec...
[M::mem_process_seqs] Processed 711588 reads in 145.882 CPU sec, 4.630 real sec
[M::mem_process_seqs] Processed 710122 reads in 95.721 CPU sec, 3.033 real sec
sorting block 117, #reads = 1081222 mem = 536876974 peak = 1190023168
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (92, 289297, 23, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 339, 672)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1564)
[M::mem_pestat] mean and std.dev: (393.45, 283.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2010)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 215, 311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 639)
[M::mem_pestat] mean and std.dev: (238.58, 117.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 803)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (458, 727, 1065)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2279)
[M::mem_pestat] mean and std.dev: (653.60, 344.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2886)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (283, 403, 924)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2206)
[M::mem_pestat] mean and std.dev: (557.09, 390.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2847)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708434 sequences (100000218 bp) in 2.339 CPU sec, 2.551 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 289780, 26, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 335, 527)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1235)
[M::mem_pestat] mean and std.dev: (331.49, 230.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1589)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 215, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 645)
[M::mem_pestat] mean and std.dev: (239.38, 118.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 811)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 762, 2177)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6153)
[M::mem_pestat] mean and std.dev: (1232.42, 1448.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8141)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 393, 1063)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2823)
[M::mem_pestat] mean and std.dev: (442.64, 421.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3703)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707996 sequences (100000068 bp) in 1.500 CPU sec, 1.504 real sec...
[M::mem_process_seqs] Processed 709330 reads in 148.755 CPU sec, 4.805 real sec
[M::mem_process_seqs] Processed 709368 reads in 98.898 CPU sec, 3.146 real sec
sorting block 118, #reads = 1082578 mem = 536879505 peak = 1190023168
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (96, 289433, 27, 81)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 268, 908)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2420)
[M::mem_pestat] mean and std.dev: (515.51, 558.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3176)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 216, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 651)
[M::mem_pestat] mean and std.dev: (241.14, 119.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 819)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (357, 644, 1483)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3735)
[M::mem_pestat] mean and std.dev: (974.92, 891.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4861)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 246, 802)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2078)
[M::mem_pestat] mean and std.dev: (350.12, 317.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2716)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708200 sequences (100000090 bp) in 2.317 CPU sec, 2.499 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 288947, 28, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 244, 981)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2627)
[M::mem_pestat] mean and std.dev: (597.47, 692.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3450)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 218, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 658)
[M::mem_pestat] mean and std.dev: (242.57, 120.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 828)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (512, 1513, 3264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8768)
[M::mem_pestat] mean and std.dev: (1820.71, 1681.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11520)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 330, 1001)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2655)
[M::mem_pestat] mean and std.dev: (508.53, 514.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3482)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 708434 reads in 141.086 CPU sec, 4.485 real sec
[M::process] read 707196 sequences (100000081 bp) in 1.555 CPU sec, 1.565 real sec...
sorting block 119, #reads = 1082140 mem = 536878360 peak = 1190023168
[M::mem_process_seqs] Processed 707996 reads in 93.451 CPU sec, 2.962 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 288998, 29, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 372, 905)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2341)
[M::mem_pestat] mean and std.dev: (490.78, 517.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3059)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 217, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 655)
[M::mem_pestat] mean and std.dev: (242.40, 120.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 824)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (376, 583, 1641)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4171)
[M::mem_pestat] mean and std.dev: (989.36, 982.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5436)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 343, 675)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1673)
[M::mem_pestat] mean and std.dev: (413.11, 324.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2172)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 120, #reads = 1083729 mem = 536878523 peak = 1190805504
[M::process] read 707688 sequences (100000209 bp) in 2.282 CPU sec, 2.450 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (91, 288981, 33, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 601, 1218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3206)
[M::mem_pestat] mean and std.dev: (698.58, 603.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4200)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 219, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 662)
[M::mem_pestat] mean and std.dev: (244.14, 121.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 833)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 504, 2110)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5932)
[M::mem_pestat] mean and std.dev: (1006.70, 1126.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7843)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 318, 530)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1228)
[M::mem_pestat] mean and std.dev: (363.76, 251.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1577)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707144 sequences (100000111 bp) in 1.510 CPU sec, 1.511 real sec...
[M::mem_process_seqs] Processed 708200 reads in 143.487 CPU sec, 4.740 real sec
[M::mem_process_seqs] Processed 707196 reads in 92.121 CPU sec, 2.921 real sec
sorting block 121, #reads = 1083042 mem = 536879728 peak = 1190805504
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 288869, 34, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 319, 1558)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4344)
[M::mem_pestat] mean and std.dev: (835.08, 1022.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5737)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 218, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 655)
[M::mem_pestat] mean and std.dev: (242.56, 120.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 824)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (566, 1070, 1318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2822)
[M::mem_pestat] mean and std.dev: (1027.00, 632.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3574)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 310, 902)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2274)
[M::mem_pestat] mean and std.dev: (572.64, 541.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2960)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706578 sequences (100000157 bp) in 2.102 CPU sec, 2.188 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 288796, 43, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 318, 1707)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4707)
[M::mem_pestat] mean and std.dev: (793.07, 969.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6207)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 219, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 659)
[M::mem_pestat] mean and std.dev: (243.81, 121.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 829)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (104, 349, 918)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2546)
[M::mem_pestat] mean and std.dev: (483.05, 458.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3360)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 294, 933)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2361)
[M::mem_pestat] mean and std.dev: (365.54, 293.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3075)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706248 sequences (100000224 bp) in 1.490 CPU sec, 1.485 real sec...
[M::mem_process_seqs] Processed 707688 reads in 140.851 CPU sec, 4.482 real sec
[M::mem_process_seqs] Processed 707144 reads in 93.192 CPU sec, 2.960 real sec
sorting block 122, #reads = 1083399 mem = 536877931 peak = 1190805504
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 289086, 41, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (246, 364, 777)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1839)
[M::mem_pestat] mean and std.dev: (459.64, 349.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2370)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 221, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (246.00, 122.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 838)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (288, 1622, 2148)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5868)
[M::mem_pestat] mean and std.dev: (1357.12, 1020.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7728)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 215, 967)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2583)
[M::mem_pestat] mean and std.dev: (532.16, 593.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3391)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705814 sequences (100000236 bp) in 2.121 CPU sec, 2.202 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 288317, 32, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 348, 1113)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2989)
[M::mem_pestat] mean and std.dev: (540.05, 473.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3927)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 221, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 669)
[M::mem_pestat] mean and std.dev: (246.64, 123.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 842)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (646, 955, 1453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3067)
[M::mem_pestat] mean and std.dev: (822.39, 518.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3874)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 226, 852)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2182)
[M::mem_pestat] mean and std.dev: (403.37, 327.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2847)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705616 sequences (100000186 bp) in 1.480 CPU sec, 1.477 real sec...
[M::mem_process_seqs] Processed 706578 reads in 141.150 CPU sec, 4.715 real sec
[M::mem_process_seqs] Processed 706248 reads in 89.583 CPU sec, 2.843 real sec
sorting block 123, #reads = 1083940 mem = 536879456 peak = 1190805504
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 288266, 34, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 306, 611)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1465)
[M::mem_pestat] mean and std.dev: (429.26, 373.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1925)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 221, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 672)
[M::mem_pestat] mean and std.dev: (247.43, 124.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 846)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (309, 827, 1481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3825)
[M::mem_pestat] mean and std.dev: (810.90, 781.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4997)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 282, 779)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1999)
[M::mem_pestat] mean and std.dev: (376.95, 292.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2609)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 124, #reads = 1083548 mem = 536878213 peak = 1191944192
[M::process] read 705340 sequences (100000099 bp) in 2.096 CPU sec, 2.167 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 287970, 27, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 361, 785)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1927)
[M::mem_pestat] mean and std.dev: (519.28, 497.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2511)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 223, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (249.29, 126.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 855)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 491, 1336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3660)
[M::mem_pestat] mean and std.dev: (916.33, 899.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4822)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 425, 813)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2087)
[M::mem_pestat] mean and std.dev: (527.88, 422.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2724)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704490 sequences (100000168 bp) in 1.480 CPU sec, 1.482 real sec...
[M::mem_process_seqs] Processed 705814 reads in 138.205 CPU sec, 4.460 real sec
[M::mem_process_seqs] Processed 705616 reads in 89.569 CPU sec, 2.842 real sec
sorting block 125, #reads = 1083883 mem = 536882526 peak = 1191944192
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 287760, 35, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 394, 705)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1615)
[M::mem_pestat] mean and std.dev: (454.17, 307.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2070)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 223, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 670)
[M::mem_pestat] mean and std.dev: (247.96, 123.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 843)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (622, 847, 1842)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4282)
[M::mem_pestat] mean and std.dev: (1170.31, 945.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5502)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (266, 589, 1464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3860)
[M::mem_pestat] mean and std.dev: (755.10, 725.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5058)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703876 sequences (100000291 bp) in 2.331 CPU sec, 2.502 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (86, 287701, 35, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 316, 1125)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3005)
[M::mem_pestat] mean and std.dev: (679.43, 738.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3945)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 225, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 678)
[M::mem_pestat] mean and std.dev: (250.35, 124.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 853)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 529, 1660)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4674)
[M::mem_pestat] mean and std.dev: (938.50, 1049.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6181)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 308, 1141)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2981)
[M::mem_pestat] mean and std.dev: (504.70, 543.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3901)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705340 reads in 134.215 CPU sec, 4.333 real sec
[M::process] read 703438 sequences (100000133 bp) in 1.678 CPU sec, 1.709 real sec...
[M::mem_process_seqs] Processed 704490 reads in 90.092 CPU sec, 2.845 real sec
sorting block 126, #reads = 1082688 mem = 536879476 peak = 1191944192
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 286676, 32, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 340, 635)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1545)
[M::mem_pestat] mean and std.dev: (404.24, 308.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2000)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 226, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 681)
[M::mem_pestat] mean and std.dev: (251.51, 125.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 857)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (492, 1208, 1843)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4545)
[M::mem_pestat] mean and std.dev: (1104.06, 807.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5896)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 362, 1065)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2819)
[M::mem_pestat] mean and std.dev: (656.48, 742.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3696)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703676 sequences (100000062 bp) in 2.659 CPU sec, 2.847 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 287100, 32, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 258, 676)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1684)
[M::mem_pestat] mean and std.dev: (478.18, 437.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2228)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (252.36, 125.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 862)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (588, 1124, 4568)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12528)
[M::mem_pestat] mean and std.dev: (2738.81, 3075.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16508)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 344, 1020)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2628)
[M::mem_pestat] mean and std.dev: (681.62, 699.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3480)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703876 reads in 133.231 CPU sec, 4.241 real sec
[M::mem_process_seqs] Processed 703438 reads in 90.258 CPU sec, 2.853 real sec
[M::process] read 703574 sequences (100000188 bp) in 1.701 CPU sec, 1.755 real sec...
sorting block 127, #reads = 1081849 mem = 536888241 peak = 1191944192
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 287232, 33, 105)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 304, 667)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1603)
[M::mem_pestat] mean and std.dev: (360.45, 280.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2071)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (252.85, 126.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 599, 1462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3844)
[M::mem_pestat] mean and std.dev: (942.19, 1047.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5131)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 392, 784)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1948)
[M::mem_pestat] mean and std.dev: (437.55, 335.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2530)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703134 sequences (100000085 bp) in 2.154 CPU sec, 2.244 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (84, 287098, 53, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 368, 1012)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2698)
[M::mem_pestat] mean and std.dev: (605.37, 621.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3541)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (252.65, 126.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 862)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 420, 1197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3229)
[M::mem_pestat] mean and std.dev: (680.53, 719.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4245)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 412, 747)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1755)
[M::mem_pestat] mean and std.dev: (482.86, 338.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2259)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703676 reads in 133.836 CPU sec, 4.264 real sec
sorting block 128, #reads = 1081747 mem = 536881687 peak = 1191944192
[M::process] read 703028 sequences (100000098 bp) in 1.490 CPU sec, 1.494 real sec...
[M::mem_process_seqs] Processed 703574 reads in 90.548 CPU sec, 2.866 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 287006, 36, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 271, 531)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1255)
[M::mem_pestat] mean and std.dev: (298.67, 185.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1617)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 229, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (254.02, 127.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 896, 2265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6487)
[M::mem_pestat] mean and std.dev: (1275.69, 1265.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8598)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 353, 1082)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2824)
[M::mem_pestat] mean and std.dev: (689.04, 686.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3695)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 129, #reads = 1080918 mem = 536878967 peak = 1198051328
[M::process] read 710720 sequences (100000066 bp) in 2.556 CPU sec, 2.755 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 286743, 23, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 435, 1808)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5008)
[M::mem_pestat] mean and std.dev: (829.11, 881.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6608)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 229, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (254.39, 127.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (634, 904, 3161)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8215)
[M::mem_pestat] mean and std.dev: (1857.17, 1821.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10742)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 267, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 974)
[M::mem_pestat] mean and std.dev: (285.08, 171.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1238)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703134 reads in 137.112 CPU sec, 4.361 real sec
[M::mem_process_seqs] Processed 703028 reads in 94.559 CPU sec, 2.987 real sec
[M::process] read 712796 sequences (100000173 bp) in 1.723 CPU sec, 1.786 real sec...
sorting block 130, #reads = 1080230 mem = 536881816 peak = 1198051328
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 289121, 25, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 355, 1532)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4118)
[M::mem_pestat] mean and std.dev: (772.41, 851.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5411)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 211, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 628)
[M::mem_pestat] mean and std.dev: (235.32, 117.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 789)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 507, 1392)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3648)
[M::mem_pestat] mean and std.dev: (923.72, 891.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4776)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 421, 786)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1950)
[M::mem_pestat] mean and std.dev: (499.02, 401.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2532)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 711774 sequences (100000044 bp) in 2.045 CPU sec, 2.111 real sec...
[M::process] read 709904 sequences (100000109 bp) in 1.380 CPU sec, 1.377 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 289732, 32, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 344, 713)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1807)
[M::mem_pestat] mean and std.dev: (461.77, 386.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2354)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 207, 298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 610)
[M::mem_pestat] mean and std.dev: (229.45, 112.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 766)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (386, 1257, 1922)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4994)
[M::mem_pestat] mean and std.dev: (1041.96, 755.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6530)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 359, 782)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1942)
[M::mem_pestat] mean and std.dev: (451.12, 371.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2522)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 710720 reads in 150.745 CPU sec, 4.804 real sec
[M::mem_process_seqs] Processed 712796 reads in 95.226 CPU sec, 3.033 real sec
sorting block 131, #reads = 1072645 mem = 536881307 peak = 1198051328
[M::process] read 708958 sequences (100000279 bp) in 2.430 CPU sec, 2.634 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 289843, 24, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 277, 712)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1802)
[M::mem_pestat] mean and std.dev: (458.45, 460.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2347)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 213, 310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 638)
[M::mem_pestat] mean and std.dev: (237.56, 117.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 802)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (350, 945, 1248)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3044)
[M::mem_pestat] mean and std.dev: (651.84, 403.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3942)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 270, 1072)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2824)
[M::mem_pestat] mean and std.dev: (521.25, 574.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3700)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 709904 reads in 74.160 CPU sec, 2.341 real sec
sorting block 132, #reads = 1085721 mem = 536879989 peak = 1198051328
[M::process] read 708590 sequences (100000135 bp) in 1.886 CPU sec, 1.964 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 289095, 37, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 385, 883)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2247)
[M::mem_pestat] mean and std.dev: (530.72, 522.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2929)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 210, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 621)
[M::mem_pestat] mean and std.dev: (233.07, 115.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 780)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (431, 967, 2436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6446)
[M::mem_pestat] mean and std.dev: (1439.22, 1290.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8451)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 319, 770)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1902)
[M::mem_pestat] mean and std.dev: (438.93, 382.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2468)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 289519, 41, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 360, 953)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2439)
[M::mem_pestat] mean and std.dev: (547.77, 463.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3182)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 216, 314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 648)
[M::mem_pestat] mean and std.dev: (239.82, 118.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 815)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (366, 626, 1155)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2733)
[M::mem_pestat] mean and std.dev: (720.74, 522.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3522)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 358, 851)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2079)
[M::mem_pestat] mean and std.dev: (552.30, 462.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2693)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 711774 reads in 206.696 CPU sec, 6.575 real sec
[M::mem_process_seqs] Processed 708958 reads in 105.241 CPU sec, 3.340 real sec
[M::process] read 708252 sequences (100000069 bp) in 1.897 CPU sec, 1.982 real sec...
sorting block 133, #reads = 1086416 mem = 536877999 peak = 1198051328
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 289528, 23, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 297, 617)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1489)
[M::mem_pestat] mean and std.dev: (312.81, 192.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1925)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 216, 314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 648)
[M::mem_pestat] mean and std.dev: (240.52, 119.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 815)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (433, 825, 1667)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4135)
[M::mem_pestat] mean and std.dev: (1143.61, 967.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5369)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 364, 1053)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2693)
[M::mem_pestat] mean and std.dev: (471.67, 380.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3513)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707388 sequences (100000122 bp) in 2.491 CPU sec, 2.697 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 288714, 38, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 338, 799)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2051)
[M::mem_pestat] mean and std.dev: (429.64, 368.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2677)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 217, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 652)
[M::mem_pestat] mean and std.dev: (241.74, 120.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 820)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (473, 913, 1145)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2489)
[M::mem_pestat] mean and std.dev: (930.57, 559.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3168)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 296, 451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 933)
[M::mem_pestat] mean and std.dev: (295.57, 161.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1174)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 708590 reads in 130.803 CPU sec, 4.178 real sec
[M::mem_process_seqs] Processed 708252 reads in 87.386 CPU sec, 2.774 real sec
sorting block 134, #reads = 1086182 mem = 536877582 peak = 1198051328
[M::process] read 706928 sequences (100000128 bp) in 2.123 CPU sec, 2.294 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 288919, 32, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 370, 1167)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3067)
[M::mem_pestat] mean and std.dev: (651.34, 677.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4017)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 219, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 656)
[M::mem_pestat] mean and std.dev: (243.27, 120.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 825)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (272, 625, 993)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2435)
[M::mem_pestat] mean and std.dev: (722.87, 577.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3156)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 313, 976)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2474)
[M::mem_pestat] mean and std.dev: (640.15, 603.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3223)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 135, #reads = 1087041 mem = 536879473 peak = 1198051328
[M::process] read 707012 sequences (100000104 bp) in 2.301 CPU sec, 2.504 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 288639, 33, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 378, 788)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2070)
[M::mem_pestat] mean and std.dev: (382.20, 337.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2711)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 220, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 665)
[M::mem_pestat] mean and std.dev: (244.65, 121.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 837)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (427, 626, 1610)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3976)
[M::mem_pestat] mean and std.dev: (824.10, 558.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5159)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 322, 706)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1692)
[M::mem_pestat] mean and std.dev: (375.32, 319.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2185)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707388 reads in 131.021 CPU sec, 4.194 real sec
[M::mem_process_seqs] Processed 706928 reads in 88.222 CPU sec, 2.798 real sec
[M::process] read 706532 sequences (100000096 bp) in 1.696 CPU sec, 1.760 real sec...
sorting block 136, #reads = 1085561 mem = 536878988 peak = 1198051328
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 289259, 44, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 350, 798)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1970)
[M::mem_pestat] mean and std.dev: (363.62, 289.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2556)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 221, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 657)
[M::mem_pestat] mean and std.dev: (244.40, 121.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 826)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 832, 1811)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5043)
[M::mem_pestat] mean and std.dev: (1033.36, 1044.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6659)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 612, 1331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3521)
[M::mem_pestat] mean and std.dev: (852.67, 821.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4616)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705510 sequences (100000042 bp) in 2.417 CPU sec, 2.649 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 288524, 22, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 443, 1351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3655)
[M::mem_pestat] mean and std.dev: (724.11, 720.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4807)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 221, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 663)
[M::mem_pestat] mean and std.dev: (245.26, 121.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 892, 1868)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5120)
[M::mem_pestat] mean and std.dev: (857.06, 688.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6746)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 310, 562)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1348)
[M::mem_pestat] mean and std.dev: (322.93, 211.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1741)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707012 reads in 131.262 CPU sec, 4.187 real sec
[M::mem_process_seqs] Processed 706532 reads in 88.217 CPU sec, 2.796 real sec
[M::process] read 705780 sequences (100000231 bp) in 2.077 CPU sec, 2.245 real sec...
sorting block 137, #reads = 1087005 mem = 536875785 peak = 1198051328
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 288450, 22, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 298, 1171)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3149)
[M::mem_pestat] mean and std.dev: (450.30, 501.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4138)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 224, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 673)
[M::mem_pestat] mean and std.dev: (247.44, 122.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 847)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (916, 1646, 2216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4816)
[M::mem_pestat] mean and std.dev: (1854.23, 1279.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6971)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 340, 495)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 987)
[M::mem_pestat] mean and std.dev: (350.58, 184.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1233)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 287874, 42, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 483, 1136)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3026)
[M::mem_pestat] mean and std.dev: (649.50, 512.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3971)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 224, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 673)
[M::mem_pestat] mean and std.dev: (247.90, 123.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 847)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (302, 538, 1149)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2843)
[M::mem_pestat] mean and std.dev: (784.44, 796.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3970)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 322, 641)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1533)
[M::mem_pestat] mean and std.dev: (347.55, 238.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1979)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705560 sequences (100000034 bp) in 2.484 CPU sec, 2.674 real sec...
[M::mem_process_seqs] Processed 705510 reads in 128.845 CPU sec, 4.128 real sec
[M::mem_process_seqs] Processed 705780 reads in 86.828 CPU sec, 2.756 real sec
sorting block 138, #reads = 1086638 mem = 536879353 peak = 1198051328
[M::process] read 705336 sequences (100000200 bp) in 1.859 CPU sec, 1.943 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 288209, 26, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 313, 891)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2299)
[M::mem_pestat] mean and std.dev: (520.52, 515.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3003)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 224, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 676)
[M::mem_pestat] mean and std.dev: (248.56, 123.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 851)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (654, 1544, 3354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8754)
[M::mem_pestat] mean and std.dev: (1791.87, 1549.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11454)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 284, 551)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1285)
[M::mem_pestat] mean and std.dev: (363.54, 265.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1652)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 139, #reads = 1086122 mem = 536877338 peak = 1198051328
[M::process] read 706358 sequences (100000216 bp) in 1.871 CPU sec, 1.930 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (86, 288033, 28, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 403, 894)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2244)
[M::mem_pestat] mean and std.dev: (481.81, 407.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2919)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 225, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (249.77, 124.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 856)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (379, 508, 1451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3595)
[M::mem_pestat] mean and std.dev: (598.29, 454.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4667)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 354, 860)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2110)
[M::mem_pestat] mean and std.dev: (510.65, 403.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2735)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705560 reads in 128.827 CPU sec, 4.101 real sec
[M::mem_process_seqs] Processed 705336 reads in 86.448 CPU sec, 2.737 real sec
[M::process] read 706386 sequences (100000166 bp) in 1.715 CPU sec, 1.804 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 288509, 34, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 432, 1237)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3347)
[M::mem_pestat] mean and std.dev: (649.23, 647.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4402)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 222, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (245.63, 121.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 838)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 517, 727)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1707)
[M::mem_pestat] mean and std.dev: (491.24, 386.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2197)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 328, 1111)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2843)
[M::mem_pestat] mean and std.dev: (608.79, 562.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3709)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 140, #reads = 1086666 mem = 536877853 peak = 1198051328
[M::process] read 706124 sequences (100000014 bp) in 2.493 CPU sec, 2.684 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 288948, 28, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 355, 1975)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5515)
[M::mem_pestat] mean and std.dev: (1042.42, 1209.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7285)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 220, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 660)
[M::mem_pestat] mean and std.dev: (244.33, 120.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 830)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 516, 1934)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5406)
[M::mem_pestat] mean and std.dev: (725.58, 770.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7142)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 263, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 912)
[M::mem_pestat] mean and std.dev: (277.84, 171.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1152)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706358 reads in 131.253 CPU sec, 4.197 real sec
[M::mem_process_seqs] Processed 706386 reads in 88.046 CPU sec, 2.790 real sec
[M::process] read 706078 sequences (100000229 bp) in 1.888 CPU sec, 1.992 real sec...
sorting block 141, #reads = 1085473 mem = 536876857 peak = 1198051328
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 288943, 25, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 298, 539)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1295)
[M::mem_pestat] mean and std.dev: (340.12, 248.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1673)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 222, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 672)
[M::mem_pestat] mean and std.dev: (246.74, 122.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 846)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (317, 758, 2562)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7052)
[M::mem_pestat] mean and std.dev: (1391.44, 1503.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9297)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 427, 729)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1807)
[M::mem_pestat] mean and std.dev: (425.74, 327.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2346)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705292 sequences (100000294 bp) in 2.199 CPU sec, 2.391 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 288559, 23, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 347, 1304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3498)
[M::mem_pestat] mean and std.dev: (884.90, 899.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4595)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 222, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 673)
[M::mem_pestat] mean and std.dev: (247.41, 123.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 847)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1614, 1646, 5759)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 14049)
[M::mem_pestat] mean and std.dev: (2901.65, 2493.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 18194)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 244, 1160)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3104)
[M::mem_pestat] mean and std.dev: (626.82, 720.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4076)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706124 reads in 132.789 CPU sec, 4.233 real sec
[M::mem_process_seqs] Processed 706078 reads in 89.116 CPU sec, 2.820 real sec
sorting block 142, #reads = 1087104 mem = 536879088 peak = 1198051328
[M::process] read 704340 sequences (100000110 bp) in 1.578 CPU sec, 1.625 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 288067, 36, 81)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 409, 728)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1830)
[M::mem_pestat] mean and std.dev: (415.76, 301.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2381)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (248.54, 123.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 848)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (460, 814, 1688)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4144)
[M::mem_pestat] mean and std.dev: (1036.34, 826.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5372)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (263, 376, 804)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1886)
[M::mem_pestat] mean and std.dev: (518.13, 418.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2427)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 143, #reads = 1084603 mem = 536883540 peak = 1212628992
[M::process] read 704058 sequences (100000006 bp) in 2.005 CPU sec, 2.086 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 287775, 35, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 445, 1704)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4760)
[M::mem_pestat] mean and std.dev: (704.17, 718.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6288)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 225, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 675)
[M::mem_pestat] mean and std.dev: (249.82, 124.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 849)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (350, 836, 2453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6659)
[M::mem_pestat] mean and std.dev: (1615.20, 1720.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8762)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 454, 1490)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4090)
[M::mem_pestat] mean and std.dev: (930.99, 1054.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5390)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704434 sequences (100000105 bp) in 1.320 CPU sec, 1.316 real sec...
[M::mem_process_seqs] Processed 705292 reads in 132.336 CPU sec, 4.213 real sec
[M::mem_process_seqs] Processed 704340 reads in 87.834 CPU sec, 2.795 real sec
sorting block 144, #reads = 1085054 mem = 536884015 peak = 1212628992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (103, 287214, 28, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 422, 924)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2336)
[M::mem_pestat] mean and std.dev: (613.88, 561.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3042)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 226, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684)
[M::mem_pestat] mean and std.dev: (251.70, 125.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 861)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (367, 871, 3097)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8557)
[M::mem_pestat] mean and std.dev: (1671.07, 1641.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11287)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 316, 933)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2373)
[M::mem_pestat] mean and std.dev: (389.92, 356.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3093)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703868 sequences (100000142 bp) in 2.103 CPU sec, 2.174 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 287803, 32, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 274, 1346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3642)
[M::mem_pestat] mean and std.dev: (683.47, 733.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4790)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 226, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 681)
[M::mem_pestat] mean and std.dev: (250.92, 125.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 857)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (310, 489, 1370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3490)
[M::mem_pestat] mean and std.dev: (739.60, 702.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4550)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 257, 903)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2357)
[M::mem_pestat] mean and std.dev: (516.98, 504.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3084)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703810 sequences (100000025 bp) in 1.390 CPU sec, 1.387 real sec...
[M::mem_process_seqs] Processed 704058 reads in 131.738 CPU sec, 4.186 real sec
[M::mem_process_seqs] Processed 704434 reads in 88.323 CPU sec, 2.809 real sec
sorting block 145, #reads = 1083957 mem = 536887976 peak = 1212628992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (79, 287093, 29, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 410, 850)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2138)
[M::mem_pestat] mean and std.dev: (451.70, 338.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2782)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 226, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (250.97, 125.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (423, 502, 3317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9105)
[M::mem_pestat] mean and std.dev: (1480.32, 1879.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11999)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 341, 740)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1742)
[M::mem_pestat] mean and std.dev: (395.90, 297.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2243)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704086 sequences (100000053 bp) in 2.075 CPU sec, 2.155 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 287190, 42, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 224, 394)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 882)
[M::mem_pestat] mean and std.dev: (231.78, 128.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1126)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (251.35, 125.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 889, 2025)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5659)
[M::mem_pestat] mean and std.dev: (1377.02, 1375.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7476)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 300, 773)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1983)
[M::mem_pestat] mean and std.dev: (429.68, 388.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2588)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704520 sequences (100000264 bp) in 1.410 CPU sec, 1.410 real sec...
[M::mem_process_seqs] Processed 703868 reads in 134.294 CPU sec, 4.270 real sec
[M::mem_process_seqs] Processed 703810 reads in 89.686 CPU sec, 2.858 real sec
sorting block 146, #reads = 1083620 mem = 536882436 peak = 1219211264
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 287955, 36, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 443, 853)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2165)
[M::mem_pestat] mean and std.dev: (505.77, 404.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2821)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 225, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 675)
[M::mem_pestat] mean and std.dev: (250.07, 124.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 849)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 622, 2087)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5963)
[M::mem_pestat] mean and std.dev: (1175.74, 1225.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7901)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 533, 1723)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4709)
[M::mem_pestat] mean and std.dev: (1183.77, 1277.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6294)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703258 sequences (100000165 bp) in 2.496 CPU sec, 2.672 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 287864, 43, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 419, 1239)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3305)
[M::mem_pestat] mean and std.dev: (615.58, 552.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4338)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 225, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (248.99, 123.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 848)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 590, 1488)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4178)
[M::mem_pestat] mean and std.dev: (955.40, 898.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5523)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 407, 869)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2175)
[M::mem_pestat] mean and std.dev: (506.74, 378.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2828)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704086 reads in 135.718 CPU sec, 4.316 real sec
sorting block 147, #reads = 1081882 mem = 536879800 peak = 1219211264
[M::process] read 703060 sequences (100000079 bp) in 1.510 CPU sec, 1.517 real sec...
[M::mem_process_seqs] Processed 704520 reads in 90.978 CPU sec, 2.895 real sec
sorting block 148, #reads = 1082449 mem = 536878713 peak = 1219211264
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 287399, 50, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 299, 663)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1619)
[M::mem_pestat] mean and std.dev: (437.21, 373.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2097)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (252.54, 125.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 862)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 600, 1120)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2830)
[M::mem_pestat] mean and std.dev: (631.15, 434.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3685)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 307, 1316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3498)
[M::mem_pestat] mean and std.dev: (763.88, 756.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4589)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703394 sequences (100000210 bp) in 2.197 CPU sec, 2.363 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 286534, 31, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 326, 1107)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2863)
[M::mem_pestat] mean and std.dev: (651.33, 704.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3741)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 228, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (252.17, 124.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 859)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (735, 1483, 2678)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6564)
[M::mem_pestat] mean and std.dev: (2042.53, 2007.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10073)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 382, 926)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2386)
[M::mem_pestat] mean and std.dev: (546.07, 550.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3116)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703258 reads in 136.686 CPU sec, 4.347 real sec
[M::process] read 703568 sequences (100000217 bp) in 1.470 CPU sec, 1.468 real sec...
[M::mem_process_seqs] Processed 703060 reads in 91.003 CPU sec, 2.887 real sec
sorting block 149, #reads = 1082738 mem = 536881826 peak = 1219211264
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 286889, 33, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 368, 810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2048)
[M::mem_pestat] mean and std.dev: (489.86, 406.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2667)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (251.93, 125.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 896, 2191)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6031)
[M::mem_pestat] mean and std.dev: (1267.79, 1120.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7951)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 342, 1289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3477)
[M::mem_pestat] mean and std.dev: (694.67, 724.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4571)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703028 sequences (100000112 bp) in 2.175 CPU sec, 2.233 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 286881, 38, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 403, 776)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1960)
[M::mem_pestat] mean and std.dev: (434.00, 322.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2552)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (251.21, 124.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (262, 728, 1070)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2686)
[M::mem_pestat] mean and std.dev: (729.89, 562.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3494)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 355, 769)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1959)
[M::mem_pestat] mean and std.dev: (521.50, 503.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2554)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703432 sequences (100000089 bp) in 1.450 CPU sec, 1.456 real sec...
[M::mem_process_seqs] Processed 703394 reads in 140.393 CPU sec, 4.464 real sec
[M::mem_process_seqs] Processed 703568 reads in 94.928 CPU sec, 3.019 real sec
sorting block 150, #reads = 1080353 mem = 536885685 peak = 1219211264
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 286776, 41, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 289, 989)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2587)
[M::mem_pestat] mean and std.dev: (588.69, 628.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3386)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (252.72, 126.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 862)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (286, 1181, 3304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9340)
[M::mem_pestat] mean and std.dev: (2037.07, 2526.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12358)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 276, 1091)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2875)
[M::mem_pestat] mean and std.dev: (567.31, 648.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3767)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 709648 sequences (100000294 bp) in 2.355 CPU sec, 2.407 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 286677, 35, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 347, 1155)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3105)
[M::mem_pestat] mean and std.dev: (657.51, 717.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4080)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (252.03, 125.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (273, 431, 1420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3714)
[M::mem_pestat] mean and std.dev: (842.09, 820.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4861)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 279, 478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1058)
[M::mem_pestat] mean and std.dev: (292.70, 183.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1348)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720382 sequences (100000080 bp) in 1.580 CPU sec, 1.581 real sec...
[M::mem_process_seqs] Processed 703028 reads in 147.773 CPU sec, 4.692 real sec
sorting block 151, #reads = 1077829 mem = 536881931 peak = 1219211264
[M::mem_process_seqs] Processed 703432 reads in 104.760 CPU sec, 3.332 real sec
sorting block 152, #reads = 1077040 mem = 536880773 peak = 1219211264
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 288415, 29, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 516, 1397)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3707)
[M::mem_pestat] mean and std.dev: (858.21, 822.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4862)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 213, 310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 638)
[M::mem_pestat] mean and std.dev: (238.09, 118.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 802)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 664, 3195)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9113)
[M::mem_pestat] mean and std.dev: (2017.48, 2681.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12745)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 361, 766)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1902)
[M::mem_pestat] mean and std.dev: (493.76, 465.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2470)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718840 sequences (100000282 bp) in 2.938 CPU sec, 3.122 real sec...
[M::process] read 714712 sequences (100000130 bp) in 1.660 CPU sec, 1.658 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 292746, 30, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 291, 899)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2365)
[M::mem_pestat] mean and std.dev: (539.30, 520.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3098)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 193, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 552)
[M::mem_pestat] mean and std.dev: (212.83, 101.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 691)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 410, 1161)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3011)
[M::mem_pestat] mean and std.dev: (649.43, 597.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3936)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 320, 798)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1972)
[M::mem_pestat] mean and std.dev: (458.18, 403.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2559)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 709648 reads in 185.904 CPU sec, 5.905 real sec
[M::mem_process_seqs] Processed 720382 reads in 123.760 CPU sec, 3.939 real sec
sorting block 153, #reads = 1071774 mem = 536878243 peak = 1219211264
[M::process] read 713012 sequences (100000165 bp) in 2.254 CPU sec, 2.313 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 292402, 37, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 259, 694)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1724)
[M::mem_pestat] mean and std.dev: (388.05, 370.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2239)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 197, 283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 575)
[M::mem_pestat] mean and std.dev: (219.27, 107.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 721)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (374, 603, 1681)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4295)
[M::mem_pestat] mean and std.dev: (935.39, 748.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5602)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 366, 1081)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2759)
[M::mem_pestat] mean and std.dev: (558.43, 592.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3598)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 712244 sequences (100000019 bp) in 1.640 CPU sec, 1.641 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 290946, 30, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 253, 810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2096)
[M::mem_pestat] mean and std.dev: (405.13, 366.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2739)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (141, 204, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 609)
[M::mem_pestat] mean and std.dev: (228.41, 113.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 765)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (380, 896, 1247)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2981)
[M::mem_pestat] mean and std.dev: (759.62, 502.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3848)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 306, 1192)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3190)
[M::mem_pestat] mean and std.dev: (490.60, 602.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4189)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 718840 reads in 173.525 CPU sec, 5.522 real sec
[M::mem_process_seqs] Processed 714712 reads in 114.383 CPU sec, 3.947 real sec
sorting block 154, #reads = 1079975 mem = 536878989 peak = 1219211264
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 290621, 27, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (128, 221, 696)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1832)
[M::mem_pestat] mean and std.dev: (343.46, 342.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2400)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 207, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 616)
[M::mem_pestat] mean and std.dev: (230.86, 114.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 774)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (386, 643, 1488)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3692)
[M::mem_pestat] mean and std.dev: (852.40, 688.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4794)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 262, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 928)
[M::mem_pestat] mean and std.dev: (262.74, 144.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1176)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 711174 sequences (100000172 bp) in 2.727 CPU sec, 2.893 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 290354, 17, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 340, 614)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1442)
[M::mem_pestat] mean and std.dev: (385.19, 269.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1856)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 209, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 626)
[M::mem_pestat] mean and std.dev: (233.38, 116.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 787)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (430, 1037, 1757)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4411)
[M::mem_pestat] mean and std.dev: (1198.88, 980.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5738)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 424, 2349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6549)
[M::mem_pestat] mean and std.dev: (990.02, 959.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8649)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 709588 sequences (100000052 bp) in 1.840 CPU sec, 1.836 real sec...
[M::mem_process_seqs] Processed 713012 reads in 172.412 CPU sec, 5.762 real sec
sorting block 155, #reads = 1080450 mem = 536881214 peak = 1219211264
[M::mem_process_seqs] Processed 712244 reads in 110.607 CPU sec, 3.501 real sec
sorting block 156, #reads = 1080142 mem = 536880122 peak = 1226055680
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 290009, 44, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 282, 558)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1290)
[M::mem_pestat] mean and std.dev: (347.70, 262.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1656)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 211, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 631)
[M::mem_pestat] mean and std.dev: (235.43, 116.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 793)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 576, 1588)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4484)
[M::mem_pestat] mean and std.dev: (785.66, 865.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5932)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 529, 1035)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2675)
[M::mem_pestat] mean and std.dev: (638.22, 605.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3495)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 709406 sequences (100000264 bp) in 2.338 CPU sec, 2.404 real sec...
[M::process] read 709044 sequences (100000167 bp) in 1.640 CPU sec, 1.640 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (90, 289678, 37, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 365, 654)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1520)
[M::mem_pestat] mean and std.dev: (415.47, 302.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1953)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 215, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 647)
[M::mem_pestat] mean and std.dev: (239.62, 119.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 814)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (68, 662, 1556)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4532)
[M::mem_pestat] mean and std.dev: (834.58, 805.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6020)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 280, 532)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1158)
[M::mem_pestat] mean and std.dev: (327.21, 196.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1471)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 711174 reads in 162.371 CPU sec, 5.168 real sec
[M::mem_process_seqs] Processed 709588 reads in 107.606 CPU sec, 3.431 real sec
sorting block 157, #reads = 1080788 mem = 536877660 peak = 1226055680
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 289123, 40, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 224, 578)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1406)
[M::mem_pestat] mean and std.dev: (276.22, 217.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1820)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 216, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 651)
[M::mem_pestat] mean and std.dev: (241.12, 120.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 819)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (320, 588, 1139)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2777)
[M::mem_pestat] mean and std.dev: (752.82, 699.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3596)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 514, 1633)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4391)
[M::mem_pestat] mean and std.dev: (997.75, 1006.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5770)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708102 sequences (100000013 bp) in 2.580 CPU sec, 2.753 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (91, 289105, 38, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 511, 1458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3914)
[M::mem_pestat] mean and std.dev: (832.92, 880.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5142)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 217, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 657)
[M::mem_pestat] mean and std.dev: (242.02, 120.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 827)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 316, 1004)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2694)
[M::mem_pestat] mean and std.dev: (600.86, 652.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3539)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 295, 878)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2256)
[M::mem_pestat] mean and std.dev: (520.64, 498.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2945)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706886 sequences (100000070 bp) in 1.620 CPU sec, 1.623 real sec...
[M::mem_process_seqs] Processed 709406 reads in 167.403 CPU sec, 5.374 real sec
[M::mem_process_seqs] Processed 709044 reads in 108.945 CPU sec, 3.456 real sec
sorting block 158, #reads = 1081458 mem = 536879025 peak = 1226055680
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (92, 288540, 45, 91)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 486, 887)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2201)
[M::mem_pestat] mean and std.dev: (641.80, 534.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2858)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 218, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (243.79, 122.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 836)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (443, 900, 1779)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4451)
[M::mem_pestat] mean and std.dev: (1198.37, 1006.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5787)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 304, 641)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1561)
[M::mem_pestat] mean and std.dev: (348.94, 241.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2021)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706390 sequences (100000196 bp) in 2.556 CPU sec, 2.676 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 288306, 38, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 429, 1430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3910)
[M::mem_pestat] mean and std.dev: (637.62, 651.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5150)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 221, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 669)
[M::mem_pestat] mean and std.dev: (246.37, 123.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 842)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 621, 1226)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3260)
[M::mem_pestat] mean and std.dev: (744.11, 645.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4277)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 315, 1303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3571)
[M::mem_pestat] mean and std.dev: (743.22, 865.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4705)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707130 sequences (100000034 bp) in 1.640 CPU sec, 1.637 real sec...
[M::mem_process_seqs] Processed 708102 reads in 160.047 CPU sec, 5.083 real sec
sorting block 159, #reads = 1079652 mem = 536880485 peak = 1226055680
[M::mem_process_seqs] Processed 706886 reads in 107.393 CPU sec, 3.414 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 288600, 34, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 284, 762)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1948)
[M::mem_pestat] mean and std.dev: (441.86, 407.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2541)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 223, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 678)
[M::mem_pestat] mean and std.dev: (248.27, 124.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 861, 1464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3930)
[M::mem_pestat] mean and std.dev: (806.87, 612.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5163)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 291, 1039)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2709)
[M::mem_pestat] mean and std.dev: (456.64, 512.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3544)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 160, #reads = 1078643 mem = 536879237 peak = 1226055680
[M::process] read 706004 sequences (100000222 bp) in 2.566 CPU sec, 2.731 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (94, 287992, 32, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 291, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1047)
[M::mem_pestat] mean and std.dev: (294.35, 193.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1344)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 219, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 659)
[M::mem_pestat] mean and std.dev: (243.95, 121.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 829)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (354, 532, 1850)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4842)
[M::mem_pestat] mean and std.dev: (862.07, 841.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6338)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 323, 1100)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2818)
[M::mem_pestat] mean and std.dev: (560.38, 559.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3677)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705004 sequences (100000092 bp) in 1.630 CPU sec, 1.634 real sec...
[M::mem_process_seqs] Processed 706390 reads in 163.975 CPU sec, 5.324 real sec
[M::mem_process_seqs] Processed 707130 reads in 106.137 CPU sec, 3.364 real sec
sorting block 161, #reads = 1080181 mem = 536883656 peak = 1226055680
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (90, 287770, 35, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 342, 1452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3974)
[M::mem_pestat] mean and std.dev: (883.23, 1013.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5235)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 223, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 670)
[M::mem_pestat] mean and std.dev: (247.37, 123.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 843)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (312, 475, 893)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2055)
[M::mem_pestat] mean and std.dev: (491.77, 355.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2636)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 446, 1773)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4871)
[M::mem_pestat] mean and std.dev: (947.31, 928.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6420)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704724 sequences (100000011 bp) in 2.288 CPU sec, 2.421 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 288121, 30, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 237, 770)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1958)
[M::mem_pestat] mean and std.dev: (385.05, 353.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2552)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 225, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (250.83, 125.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 860)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (536, 1128, 2356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5996)
[M::mem_pestat] mean and std.dev: (1599.57, 1507.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7816)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 462, 1248)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3264)
[M::mem_pestat] mean and std.dev: (604.23, 631.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4272)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706004 reads in 145.152 CPU sec, 4.610 real sec
[M::process] read 704606 sequences (100000075 bp) in 1.804 CPU sec, 1.807 real sec...
[M::mem_process_seqs] Processed 705004 reads in 96.998 CPU sec, 3.069 real sec
sorting block 162, #reads = 1079472 mem = 536881885 peak = 1226055680
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (89, 287534, 24, 88)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 355, 788)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1928)
[M::mem_pestat] mean and std.dev: (462.39, 414.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2498)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 225, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684)
[M::mem_pestat] mean and std.dev: (251.35, 126.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 861)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 897, 1695)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4681)
[M::mem_pestat] mean and std.dev: (988.25, 842.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6174)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 326, 751)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1773)
[M::mem_pestat] mean and std.dev: (454.79, 346.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2284)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704250 sequences (100000131 bp) in 2.493 CPU sec, 2.652 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (92, 286701, 46, 86)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 345, 780)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1960)
[M::mem_pestat] mean and std.dev: (517.66, 471.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2550)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 225, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (250.88, 125.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 860)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 706, 1319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3505)
[M::mem_pestat] mean and std.dev: (740.93, 723.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4598)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 454, 798)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1882)
[M::mem_pestat] mean and std.dev: (514.79, 346.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2424)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704724 reads in 142.926 CPU sec, 4.762 real sec
[M::process] read 703748 sequences (100000228 bp) in 1.653 CPU sec, 1.662 real sec...
sorting block 163, #reads = 1080836 mem = 536891169 peak = 1226055680
[M::mem_process_seqs] Processed 704606 reads in 95.698 CPU sec, 3.019 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (81, 287116, 27, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 351, 825)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2015)
[M::mem_pestat] mean and std.dev: (543.62, 479.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2610)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 227, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684)
[M::mem_pestat] mean and std.dev: (251.68, 125.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 861)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (585, 671, 1760)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4110)
[M::mem_pestat] mean and std.dev: (1266.78, 1107.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5695)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 383, 856)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2228)
[M::mem_pestat] mean and std.dev: (484.70, 469.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2914)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 164, #reads = 1081154 mem = 536878285 peak = 1226055680
[M::process] read 703448 sequences (100000300 bp) in 2.630 CPU sec, 2.787 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 287145, 31, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 436, 1539)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4181)
[M::mem_pestat] mean and std.dev: (842.61, 853.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5502)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 676)
[M::mem_pestat] mean and std.dev: (250.61, 123.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 850)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 1152, 1608)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4554)
[M::mem_pestat] mean and std.dev: (907.26, 920.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6027)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 330, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 996)
[M::mem_pestat] mean and std.dev: (319.00, 210.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1270)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704250 reads in 140.670 CPU sec, 4.456 real sec
[M::process] read 703614 sequences (100000125 bp) in 1.743 CPU sec, 1.770 real sec...
[M::mem_process_seqs] Processed 703748 reads in 94.048 CPU sec, 2.960 real sec
sorting block 165, #reads = 1079950 mem = 536878336 peak = 1226055680
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 286804, 44, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 435, 1369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3721)
[M::mem_pestat] mean and std.dev: (781.76, 898.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4897)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (252.13, 125.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (347, 676, 1194)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2888)
[M::mem_pestat] mean and std.dev: (723.69, 609.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3735)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 372, 1166)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3046)
[M::mem_pestat] mean and std.dev: (577.38, 560.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3986)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702920 sequences (100000019 bp) in 2.378 CPU sec, 2.525 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 286575, 34, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 445, 695)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1661)
[M::mem_pestat] mean and std.dev: (480.47, 365.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2144)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (251.61, 125.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 982, 1776)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5010)
[M::mem_pestat] mean and std.dev: (1129.85, 1110.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6627)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 320, 1013)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2645)
[M::mem_pestat] mean and std.dev: (597.43, 612.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3461)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703448 reads in 138.893 CPU sec, 4.428 real sec
[M::mem_process_seqs] Processed 703614 reads in 94.160 CPU sec, 2.960 real sec
[M::process] read 703106 sequences (100000247 bp) in 1.998 CPU sec, 2.066 real sec...
sorting block 166, #reads = 1081692 mem = 536880255 peak = 1226055680
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 286405, 31, 84)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 216, 704)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1778)
[M::mem_pestat] mean and std.dev: (387.00, 417.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2315)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (251.78, 124.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (462, 675, 1882)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4722)
[M::mem_pestat] mean and std.dev: (960.28, 818.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6142)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 361, 886)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2198)
[M::mem_pestat] mean and std.dev: (470.77, 354.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2854)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702886 sequences (100000260 bp) in 2.491 CPU sec, 2.671 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 287025, 27, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 316, 1440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4008)
[M::mem_pestat] mean and std.dev: (876.78, 1082.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5292)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 228, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (251.88, 124.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 855)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 269, 559)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1321)
[M::mem_pestat] mean and std.dev: (311.92, 242.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1702)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 380, 1243)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3381)
[M::mem_pestat] mean and std.dev: (789.11, 916.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4454)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702920 reads in 137.997 CPU sec, 4.389 real sec
[M::mem_process_seqs] Processed 703106 reads in 93.300 CPU sec, 2.941 real sec
sorting block 167, #reads = 1081380 mem = 536880262 peak = 1226055680
[M::process] read 702198 sequences (100000166 bp) in 2.096 CPU sec, 2.194 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 286946, 39, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 372, 1156)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3076)
[M::mem_pestat] mean and std.dev: (691.32, 760.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4036)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 230, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (253.07, 124.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 859)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (465, 1038, 1732)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4266)
[M::mem_pestat] mean and std.dev: (1094.56, 931.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5533)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 351, 785)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1853)
[M::mem_pestat] mean and std.dev: (439.02, 335.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2387)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 168, #reads = 1080980 mem = 536876841 peak = 1226055680
[M::process] read 702124 sequences (100000207 bp) in 2.419 CPU sec, 2.584 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 286862, 33, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 276, 1136)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3048)
[M::mem_pestat] mean and std.dev: (649.36, 695.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4004)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 230, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (254.67, 126.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (587, 735, 1719)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3983)
[M::mem_pestat] mean and std.dev: (1238.45, 991.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5206)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 388, 1601)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4461)
[M::mem_pestat] mean and std.dev: (734.37, 825.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5891)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702886 reads in 136.446 CPU sec, 4.354 real sec
[M::mem_process_seqs] Processed 702198 reads in 93.026 CPU sec, 2.934 real sec
[M::process] read 702618 sequences (100000035 bp) in 2.322 CPU sec, 2.481 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 286864, 27, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 381, 1415)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3801)
[M::mem_pestat] mean and std.dev: (789.03, 835.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4994)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 230, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (254.14, 125.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 330, 1055)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2729)
[M::mem_pestat] mean and std.dev: (514.88, 558.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3566)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 336, 883)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2269)
[M::mem_pestat] mean and std.dev: (571.25, 638.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3123)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 169, #reads = 1082321 mem = 536878001 peak = 1226055680
[M::process] read 702390 sequences (100000132 bp) in 2.399 CPU sec, 2.573 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 287108, 26, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 293, 494)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1038)
[M::mem_pestat] mean and std.dev: (342.32, 182.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1310)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 229, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 686)
[M::mem_pestat] mean and std.dev: (253.45, 125.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 863)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 585, 1251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3277)
[M::mem_pestat] mean and std.dev: (768.46, 744.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4290)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 326, 806)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2054)
[M::mem_pestat] mean and std.dev: (384.51, 343.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2678)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702124 reads in 135.861 CPU sec, 4.341 real sec
[M::mem_process_seqs] Processed 702618 reads in 92.427 CPU sec, 2.923 real sec
sorting block 170, #reads = 1080886 mem = 536881934 peak = 1226055680
[M::process] read 701950 sequences (100000237 bp) in 2.383 CPU sec, 2.569 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 286576, 27, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 317, 1383)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3757)
[M::mem_pestat] mean and std.dev: (703.85, 752.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4944)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 231, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (254.66, 126.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (268, 536, 1049)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2611)
[M::mem_pestat] mean and std.dev: (634.83, 567.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3392)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 278, 591)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1419)
[M::mem_pestat] mean and std.dev: (392.75, 346.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1833)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (85, 286283, 36, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 385, 927)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2361)
[M::mem_pestat] mean and std.dev: (555.92, 504.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3078)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 231, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (255.27, 126.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 723, 1369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3629)
[M::mem_pestat] mean and std.dev: (880.09, 905.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4759)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (271, 554, 1970)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5368)
[M::mem_pestat] mean and std.dev: (1215.15, 1344.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7067)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701802 sequences (100000080 bp) in 2.305 CPU sec, 2.443 real sec...
[M::mem_process_seqs] Processed 702390 reads in 133.353 CPU sec, 4.261 real sec
[M::mem_process_seqs] Processed 701950 reads in 90.031 CPU sec, 2.841 real sec
sorting block 171, #reads = 1082078 mem = 536878978 peak = 1226055680
[M::process] read 398764 sequences (56541046 bp) in 1.500 CPU sec, 1.588 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 286692, 27, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 335, 686)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1668)
[M::mem_pestat] mean and std.dev: (424.63, 406.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2159)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 232, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (256.21, 127.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 876)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (336, 783, 1307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3249)
[M::mem_pestat] mean and std.dev: (783.44, 590.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4220)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 367, 943)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2375)
[M::mem_pestat] mean and std.dev: (567.11, 578.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3091)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 162340, 18, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 332, 716)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1740)
[M::mem_pestat] mean and std.dev: (464.25, 373.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2252)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 225, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 677)
[M::mem_pestat] mean and std.dev: (249.46, 124.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 852)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (633, 1154, 2301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5637)
[M::mem_pestat] mean and std.dev: (985.07, 630.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7305)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 313, 1145)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2985)
[M::mem_pestat] mean and std.dev: (664.58, 808.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3905)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701802 reads in 117.724 CPU sec, 3.828 real sec
[M::mem_process_seqs] Processed 398764 reads in 59.647 CPU sec, 1.928 real sec
sorting block 172, #reads = 1082020 mem = 536878854 peak = 1228353536
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000c06f2
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: INTEL(R) XEON(R) PLATINUM 8559C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 187352898
overall: 70169874432 mem 22763.456 user 485.293 sys 792.869 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1136_7GC-T1-TDNA-1_A23MHWWLT4_1.L005\tPU:L005\tSM:1136_7GC-T1-TDNA-1_A23MHWWLT4_1\tLB:1136_7GC-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1136_7GC-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1136_7GC-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 792.904 sec; CPU: 23248.751 sec
sorting block 173, #reads = 1067360 mem = 530180180 peak = 1231425536
uniq header count 1
merging 174 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000c06f2
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: INTEL(R) XEON(R) PLATINUM 8559C
threads: 31 max 192
algo: util-sort
license: sentieon:util=1
output file size: 10320997253
output reads: 188591826
bam_mem_sort: 174 calls 77.616 user 2.472 sys 81.381 real
bam_write: 174 calls 176.859 user 5.603 sys 203.700 real
execute: 1 calls 42.174 user 1.338 sys 854.511 real
merge_files: 1 calls 42.145 user 1.296 sys 60.074 real
parse_chunk: 2784 calls 110.319 user 31.106 sys 153.553 real
read_chunk: 7532 calls 68.413 user 53.866 sys 748.017 real
sort_block: 1 calls 50.367 user 53.401 sys 722.891 real
write_chunk: 4746 calls 41.847 user 0.893 sys 59.075 real
overall: 3695292416 mem 2361.502 user 105.539 sys 854.538 real
ls: cannot access '*.cram': No such file or directory