This software is licensed to bgold@natera.com by Sentieon Inc.
cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1136_3MV-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 2221.647 CPU sec, 86.383 real sec
[M::process] read 683768 sequences (100000113 bp) in 1.281 CPU sec, 1.290 real sec...
[M::process] read 683628 sequences (100000230 bp) in 1.715 CPU sec, 1.757 real sec...
[M::process] read 683160 sequences (100000227 bp) in 1.612 CPU sec, 1.688 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 283363, 9, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 280, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 677)
[M::mem_pestat] mean and std.dev: (289.04, 112.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 829)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 307, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 909)
[M::mem_pestat] mean and std.dev: (328.87, 161.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1146)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (261, 421, 539)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1095)
[M::mem_pestat] mean and std.dev: (396.66, 182.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1373)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683078 sequences (100000000 bp) in 1.530 CPU sec, 1.541 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 282546, 16, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 273, 416)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 842)
[M::mem_pestat] mean and std.dev: (280.98, 115.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1055)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 310, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 917)
[M::mem_pestat] mean and std.dev: (331.13, 162.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1156)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 953, 2466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7042)
[M::mem_pestat] mean and std.dev: (1930.25, 2441.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11694)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 413, 960)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2390)
[M::mem_pestat] mean and std.dev: (575.25, 595.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3105)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 282431, 6, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 418, 788)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1960)
[M::mem_pestat] mean and std.dev: (542.69, 458.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2546)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 309, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 911)
[M::mem_pestat] mean and std.dev: (329.89, 160.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1148)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 266, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 881)
[M::mem_pestat] mean and std.dev: (283.71, 104.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1101)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683768 reads in 284.573 CPU sec, 9.322 real sec
[M::mem_process_seqs] Processed 683628 reads in 193.952 CPU sec, 6.378 real sec
[M::mem_process_seqs] Processed 683160 reads in 211.919 CPU sec, 6.994 real sec
sorting block 0, #reads = 1078146 mem = 536880714 peak = 572776448
[M::process] read 682940 sequences (100000116 bp) in 2.117 CPU sec, 2.433 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 282612, 11, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 198, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1024)
[M::mem_pestat] mean and std.dev: (279.23, 175.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1317)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 311, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 915)
[M::mem_pestat] mean and std.dev: (331.17, 161.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1153)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (679, 757, 2810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7072)
[M::mem_pestat] mean and std.dev: (1513.91, 1201.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9203)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 314, 1048)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2680)
[M::mem_pestat] mean and std.dev: (628.18, 686.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3496)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682642 sequences (100000237 bp) in 1.860 CPU sec, 2.129 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 282659, 13, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 280, 415)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 881)
[M::mem_pestat] mean and std.dev: (277.71, 123.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1114)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 315, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 931)
[M::mem_pestat] mean and std.dev: (335.30, 163.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1174)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (397, 770, 1488)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3670)
[M::mem_pestat] mean and std.dev: (889.67, 659.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4761)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (296, 455, 567)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1109)
[M::mem_pestat] mean and std.dev: (383.94, 160.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1380)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683078 reads in 182.634 CPU sec, 5.946 real sec
[M::process] read 682380 sequences (100000231 bp) in 1.702 CPU sec, 1.757 real sec...
sorting block 1, #reads = 1077730 mem = 536877165 peak = 874766336
[M::mem_process_seqs] Processed 682940 reads in 118.802 CPU sec, 3.885 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 282807, 12, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 208, 702)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1734)
[M::mem_pestat] mean and std.dev: (315.00, 212.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2250)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 316, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 933)
[M::mem_pestat] mean and std.dev: (336.47, 163.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1176)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (409, 549, 1006)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2200)
[M::mem_pestat] mean and std.dev: (641.50, 530.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2797)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 318, 738)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1770)
[M::mem_pestat] mean and std.dev: (449.21, 401.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2286)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 2, #reads = 1077923 mem = 536877586 peak = 913436672
[M::process] read 683840 sequences (100000114 bp) in 1.901 CPU sec, 2.236 real sec...
[M::process] read 681372 sequences (100000124 bp) in 1.853 CPU sec, 1.889 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 282435, 17, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 392, 1493)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4147)
[M::mem_pestat] mean and std.dev: (793.85, 918.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5474)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 319, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 948)
[M::mem_pestat] mean and std.dev: (339.78, 166.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1196)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 519, 1045)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2641)
[M::mem_pestat] mean and std.dev: (546.40, 416.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3439)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 252, 597)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1447)
[M::mem_pestat] mean and std.dev: (334.42, 246.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1872)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682642 reads in 182.246 CPU sec, 6.030 real sec
[M::mem_process_seqs] Processed 682380 reads in 119.148 CPU sec, 3.903 real sec
sorting block 3, #reads = 1078034 mem = 536879933 peak = 913436672
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 282820, 11, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 270, 540)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1326)
[M::mem_pestat] mean and std.dev: (309.85, 170.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1719)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 307, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 923)
[M::mem_pestat] mean and std.dev: (330.00, 163.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1165)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 433, 1851)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5101)
[M::mem_pestat] mean and std.dev: (921.00, 1120.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6726)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 351, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 935)
[M::mem_pestat] mean and std.dev: (323.66, 179.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1183)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681072 sequences (100000105 bp) in 2.491 CPU sec, 2.775 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 282281, 18, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 304, 707)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1701)
[M::mem_pestat] mean and std.dev: (393.41, 261.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2198)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 326, 460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 962)
[M::mem_pestat] mean and std.dev: (345.61, 167.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1213)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (42, 638, 1309)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3843)
[M::mem_pestat] mean and std.dev: (840.17, 833.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5110)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (281, 303, 490)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 908)
[M::mem_pestat] mean and std.dev: (316.12, 125.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1117)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680616 sequences (100000202 bp) in 1.825 CPU sec, 1.879 real sec...
[M::mem_process_seqs] Processed 683840 reads in 185.894 CPU sec, 6.144 real sec
[M::mem_process_seqs] Processed 681372 reads in 120.287 CPU sec, 4.000 real sec
sorting block 4, #reads = 1077128 mem = 536879752 peak = 913436672
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281447, 10, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 339, 481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1113)
[M::mem_pestat] mean and std.dev: (286.19, 137.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1429)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 328, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 963)
[M::mem_pestat] mean and std.dev: (347.53, 168.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1214)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 616, 4247)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12275)
[M::mem_pestat] mean and std.dev: (1900.30, 1922.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16289)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 361, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 846)
[M::mem_pestat] mean and std.dev: (337.10, 115.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1045)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680522 sequences (100000180 bp) in 2.297 CPU sec, 2.632 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 281525, 19, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 354, 990)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2504)
[M::mem_pestat] mean and std.dev: (526.05, 440.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3261)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 333, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 973)
[M::mem_pestat] mean and std.dev: (351.41, 169.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1226)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (321, 1168, 4006)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11376)
[M::mem_pestat] mean and std.dev: (1960.26, 1717.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 15061)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 302, 570)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1330)
[M::mem_pestat] mean and std.dev: (417.91, 316.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1710)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680584 sequences (100000182 bp) in 1.633 CPU sec, 1.660 real sec...
[M::mem_process_seqs] Processed 681072 reads in 182.706 CPU sec, 6.094 real sec
sorting block 5, #reads = 1076996 mem = 536878855 peak = 913436672
[M::mem_process_seqs] Processed 680616 reads in 118.808 CPU sec, 3.963 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 281146, 5, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 284, 502)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1092)
[M::mem_pestat] mean and std.dev: (297.46, 150.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1387)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 333, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 973)
[M::mem_pestat] mean and std.dev: (351.30, 169.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1226)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 267, 525)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1125)
[M::mem_pestat] mean and std.dev: (357.05, 229.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1425)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680490 sequences (100000261 bp) in 2.475 CPU sec, 2.730 real sec...
sorting block 6, #reads = 1076134 mem = 536876876 peak = 913436672
[M::process] read 681072 sequences (100000100 bp) in 1.708 CPU sec, 1.780 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 281064, 8, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 242, 399)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 837)
[M::mem_pestat] mean and std.dev: (287.68, 153.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1056)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 332, 464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 964)
[M::mem_pestat] mean and std.dev: (350.09, 167.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1214)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 273, 515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1169)
[M::mem_pestat] mean and std.dev: (274.90, 116.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1496)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680522 reads in 183.701 CPU sec, 6.072 real sec
[M::mem_process_seqs] Processed 680584 reads in 120.234 CPU sec, 3.932 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281595, 6, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 445, 671)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1595)
[M::mem_pestat] mean and std.dev: (446.24, 357.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2057)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 332, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 967)
[M::mem_pestat] mean and std.dev: (350.63, 168.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1218)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 451, 583)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1357)
[M::mem_pestat] mean and std.dev: (382.86, 218.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1744)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 7, #reads = 1076406 mem = 536883287 peak = 913436672
[M::process] read 680740 sequences (100000049 bp) in 2.196 CPU sec, 2.667 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 282067, 10, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 250, 514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1222)
[M::mem_pestat] mean and std.dev: (278.00, 147.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1576)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 327, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 949)
[M::mem_pestat] mean and std.dev: (345.49, 166.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1195)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (246, 253, 253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (232, 267)
[M::mem_pestat] mean and std.dev: (250.67, 3.30)
[M::mem_pestat] low and high boundaries for proper pairs: (225, 274)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 253, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 628)
[M::mem_pestat] mean and std.dev: (269.73, 109.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 766)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 679926 sequences (100000299 bp) in 1.686 CPU sec, 1.707 real sec...
[M::mem_process_seqs] Processed 680490 reads in 183.725 CPU sec, 6.040 real sec
[M::mem_process_seqs] Processed 681072 reads in 121.165 CPU sec, 3.932 real sec
sorting block 8, #reads = 1076128 mem = 536879921 peak = 913436672
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 281686, 15, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 351, 644)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1484)
[M::mem_pestat] mean and std.dev: (402.06, 262.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1904)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 327, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 949)
[M::mem_pestat] mean and std.dev: (345.54, 166.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1195)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (90, 453, 857)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2391)
[M::mem_pestat] mean and std.dev: (326.50, 288.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3158)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 329, 570)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1260)
[M::mem_pestat] mean and std.dev: (370.86, 200.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1605)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 679938 sequences (100000270 bp) in 2.646 CPU sec, 3.130 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 280716, 22, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (276, 338, 485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 903)
[M::mem_pestat] mean and std.dev: (336.56, 126.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1112)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 333, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 961)
[M::mem_pestat] mean and std.dev: (351.26, 167.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1209)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (30, 231, 231)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 633)
[M::mem_pestat] mean and std.dev: (139.65, 99.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 294, 548)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1250)
[M::mem_pestat] mean and std.dev: (326.88, 209.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1601)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 679620 sequences (100000298 bp) in 1.720 CPU sec, 1.750 real sec...
[M::mem_process_seqs] Processed 680740 reads in 184.115 CPU sec, 6.073 real sec
[M::mem_process_seqs] Processed 679926 reads in 119.776 CPU sec, 3.938 real sec
sorting block 9, #reads = 1076524 mem = 536881068 peak = 913436672
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 281023, 9, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 239, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 722)
[M::mem_pestat] mean and std.dev: (250.81, 112.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 910)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 335, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 964)
[M::mem_pestat] mean and std.dev: (352.08, 167.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1213)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 287, 503)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1089)
[M::mem_pestat] mean and std.dev: (309.89, 172.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1382)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 679220 sequences (100000134 bp) in 2.323 CPU sec, 2.657 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 281210, 6, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (330, 399, 753)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1599)
[M::mem_pestat] mean and std.dev: (434.51, 231.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2022)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 336, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 965)
[M::mem_pestat] mean and std.dev: (353.67, 168.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1214)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 287, 597)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1433)
[M::mem_pestat] mean and std.dev: (353.00, 210.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1851)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 679176 sequences (100000143 bp) in 1.794 CPU sec, 1.821 real sec...
[M::mem_process_seqs] Processed 679938 reads in 190.168 CPU sec, 6.385 real sec
sorting block 10, #reads = 1075850 mem = 536879028 peak = 913436672
[M::mem_process_seqs] Processed 679620 reads in 122.612 CPU sec, 4.062 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 281313, 12, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 357, 782)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1878)
[M::mem_pestat] mean and std.dev: (555.91, 452.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2426)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 336, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 963)
[M::mem_pestat] mean and std.dev: (353.35, 166.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1211)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (80, 494, 2290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6710)
[M::mem_pestat] mean and std.dev: (880.33, 968.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8920)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 321, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 616)
[M::mem_pestat] mean and std.dev: (255.16, 92.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 756)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 11, #reads = 1076170 mem = 536878362 peak = 913436672
[M::process] read 679586 sequences (100000050 bp) in 2.724 CPU sec, 3.015 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 280860, 11, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 237, 376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 744)
[M::mem_pestat] mean and std.dev: (281.29, 141.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 928)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 335, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 957)
[M::mem_pestat] mean and std.dev: (352.57, 166.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1203)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 1741, 2059)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5761)
[M::mem_pestat] mean and std.dev: (1251.64, 961.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7612)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (260, 352, 516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1028)
[M::mem_pestat] mean and std.dev: (396.60, 217.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1284)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 679698 sequences (100000288 bp) in 1.749 CPU sec, 1.881 real sec...
[M::mem_process_seqs] Processed 679220 reads in 182.826 CPU sec, 5.961 real sec
[M::mem_process_seqs] Processed 679176 reads in 117.397 CPU sec, 3.815 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 281163, 14, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 274, 637)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1537)
[M::mem_pestat] mean and std.dev: (427.64, 336.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1987)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 334, 464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 956)
[M::mem_pestat] mean and std.dev: (351.44, 166.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1202)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 950, 1512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4024)
[M::mem_pestat] mean and std.dev: (1083.79, 986.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5280)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (273, 387, 813)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1893)
[M::mem_pestat] mean and std.dev: (416.60, 282.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2433)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 12, #reads = 1075205 mem = 536881013 peak = 913436672
[M::process] read 679672 sequences (100000122 bp) in 2.710 CPU sec, 2.929 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 280710, 9, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 375, 579)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1369)
[M::mem_pestat] mean and std.dev: (390.03, 262.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1764)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 333, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 952)
[M::mem_pestat] mean and std.dev: (350.46, 166.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1197)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 286, 404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 816)
[M::mem_pestat] mean and std.dev: (294.54, 149.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1022)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 679586 reads in 191.144 CPU sec, 6.216 real sec
[M::process] read 680096 sequences (100000190 bp) in 1.885 CPU sec, 1.932 real sec...
[M::mem_process_seqs] Processed 679698 reads in 121.745 CPU sec, 3.984 real sec
sorting block 13, #reads = 1075358 mem = 536879873 peak = 913436672
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 280979, 9, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 355, 563)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1227)
[M::mem_pestat] mean and std.dev: (400.12, 233.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1559)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 331, 460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 948)
[M::mem_pestat] mean and std.dev: (348.90, 165.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1192)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 319, 391)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 739)
[M::mem_pestat] mean and std.dev: (295.93, 111.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 913)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 679452 sequences (100000101 bp) in 3.101 CPU sec, 3.343 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 281407, 6, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 331, 546)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1190)
[M::mem_pestat] mean and std.dev: (317.24, 135.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1512)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 330, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 939)
[M::mem_pestat] mean and std.dev: (346.96, 164.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1180)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 339, 881)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2205)
[M::mem_pestat] mean and std.dev: (476.61, 333.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2867)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 679672 reads in 185.230 CPU sec, 5.971 real sec
[M::process] read 679150 sequences (100000173 bp) in 1.799 CPU sec, 1.804 real sec...
[M::mem_process_seqs] Processed 680096 reads in 118.009 CPU sec, 3.786 real sec
sorting block 14, #reads = 1076752 mem = 536881560 peak = 913436672
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 281331, 6, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 391, 980)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2474)
[M::mem_pestat] mean and std.dev: (406.93, 293.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3221)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 331, 460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 946)
[M::mem_pestat] mean and std.dev: (349.54, 165.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1189)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 219, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 660)
[M::mem_pestat] mean and std.dev: (270.03, 143.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 845)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 679090 sequences (100000081 bp) in 2.578 CPU sec, 3.011 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281300, 8, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 227, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 581)
[M::mem_pestat] mean and std.dev: (251.94, 92.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 704)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 336, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 960)
[M::mem_pestat] mean and std.dev: (353.39, 167.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1207)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 334, 396)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 744)
[M::mem_pestat] mean and std.dev: (305.64, 115.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 918)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 679452 reads in 187.689 CPU sec, 6.159 real sec
[M::process] read 679022 sequences (100000238 bp) in 1.964 CPU sec, 1.989 real sec...
sorting block 15, #reads = 1075744 mem = 536880041 peak = 913436672
[M::mem_process_seqs] Processed 679150 reads in 122.504 CPU sec, 4.085 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 281393, 10, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 223, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 714)
[M::mem_pestat] mean and std.dev: (249.67, 88.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 888)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 334, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 951)
[M::mem_pestat] mean and std.dev: (351.97, 166.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1195)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (429, 549, 695)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1227)
[M::mem_pestat] mean and std.dev: (471.50, 154.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1493)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 292, 656)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1580)
[M::mem_pestat] mean and std.dev: (374.33, 248.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2042)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 16, #reads = 1075787 mem = 536879746 peak = 928673792
[M::process] read 678948 sequences (100000159 bp) in 2.805 CPU sec, 3.278 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 281275, 6, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 317, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 720)
[M::mem_pestat] mean and std.dev: (265.13, 103.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 898)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 336, 464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 952)
[M::mem_pestat] mean and std.dev: (353.34, 166.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1196)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 317, 510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1022)
[M::mem_pestat] mean and std.dev: (350.74, 151.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1278)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 679090 reads in 182.547 CPU sec, 6.119 real sec
[M::mem_process_seqs] Processed 679022 reads in 119.270 CPU sec, 3.982 real sec
[M::process] read 682112 sequences (100000213 bp) in 2.191 CPU sec, 2.388 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 281192, 7, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 325, 411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 887)
[M::mem_pestat] mean and std.dev: (279.87, 120.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1125)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 338, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 956)
[M::mem_pestat] mean and std.dev: (354.14, 166.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1201)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 328, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 985)
[M::mem_pestat] mean and std.dev: (295.97, 165.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1253)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 17, #reads = 1075825 mem = 536878884 peak = 928673792
[M::process] read 683538 sequences (100000133 bp) in 2.401 CPU sec, 2.812 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 282035, 10, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 341, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 875)
[M::mem_pestat] mean and std.dev: (267.42, 111.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1108)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 318, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 934)
[M::mem_pestat] mean and std.dev: (338.15, 164.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1177)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (14, 301, 610)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1802)
[M::mem_pestat] mean and std.dev: (259.67, 293.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2398)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 459, 712)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1642)
[M::mem_pestat] mean and std.dev: (498.08, 341.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2107)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 678948 reads in 189.210 CPU sec, 6.359 real sec
[M::process] read 682810 sequences (100000231 bp) in 2.350 CPU sec, 2.649 real sec...
sorting block 18, #reads = 1075220 mem = 536879840 peak = 928673792
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 282167, 8, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (128, 225, 518)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1298)
[M::mem_pestat] mean and std.dev: (312.31, 244.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1688)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 310, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 931)
[M::mem_pestat] mean and std.dev: (333.24, 165.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1175)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 271, 418)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 860)
[M::mem_pestat] mean and std.dev: (264.36, 98.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1081)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683538 reads in 106.106 CPU sec, 3.488 real sec
[M::process] read 683158 sequences (100000223 bp) in 2.352 CPU sec, 2.605 real sec...
[M::mem_process_seqs] Processed 682112 reads in 309.264 CPU sec, 10.356 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 281546, 12, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 342, 634)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1478)
[M::mem_pestat] mean and std.dev: (350.29, 179.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1900)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 313, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 931)
[M::mem_pestat] mean and std.dev: (335.05, 164.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1174)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (308, 768, 2040)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5504)
[M::mem_pestat] mean and std.dev: (899.18, 782.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7236)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 215, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 710)
[M::mem_pestat] mean and std.dev: (224.46, 106.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 888)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 19, #reads = 1077482 mem = 536879039 peak = 928673792
[M::process] read 682692 sequences (100000126 bp) in 2.421 CPU sec, 2.843 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 282464, 12, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 346, 393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 741)
[M::mem_pestat] mean and std.dev: (274.79, 96.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 915)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 316, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 940)
[M::mem_pestat] mean and std.dev: (336.49, 165.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1186)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1319, 6729, 7878)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 20996)
[M::mem_pestat] mean and std.dev: (4337.58, 3384.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 27555)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 319, 712)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1864)
[M::mem_pestat] mean and std.dev: (387.16, 342.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2440)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682810 reads in 206.231 CPU sec, 6.886 real sec
[M::process] read 682476 sequences (100000125 bp) in 2.604 CPU sec, 3.100 real sec...
sorting block 20, #reads = 1077776 mem = 536877022 peak = 928673792
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 282085, 14, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 264, 460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1080)
[M::mem_pestat] mean and std.dev: (266.23, 158.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1390)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 317, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 935)
[M::mem_pestat] mean and std.dev: (336.99, 164.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1179)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (387, 919, 2062)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5412)
[M::mem_pestat] mean and std.dev: (1270.43, 1297.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7087)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 359, 451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 865)
[M::mem_pestat] mean and std.dev: (346.78, 142.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1072)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682692 reads in 104.445 CPU sec, 3.481 real sec
[M::process] read 682286 sequences (100000116 bp) in 2.545 CPU sec, 2.804 real sec...
[M::mem_process_seqs] Processed 683158 reads in 309.471 CPU sec, 10.358 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 281688, 10, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 304, 646)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1570)
[M::mem_pestat] mean and std.dev: (395.80, 345.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2032)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 320, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 946)
[M::mem_pestat] mean and std.dev: (340.13, 166.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1193)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (805, 1365, 1412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2626)
[M::mem_pestat] mean and std.dev: (1115.25, 359.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3233)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 391, 591)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1259)
[M::mem_pestat] mean and std.dev: (343.65, 157.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1593)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 21, #reads = 1078617 mem = 536878277 peak = 928673792
[M::process] read 681804 sequences (100000106 bp) in 2.272 CPU sec, 2.685 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 282517, 18, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 322, 1080)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2848)
[M::mem_pestat] mean and std.dev: (607.42, 645.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3732)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 320, 451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 943)
[M::mem_pestat] mean and std.dev: (339.61, 165.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1189)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (362, 496, 1162)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2762)
[M::mem_pestat] mean and std.dev: (768.17, 614.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3562)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 286, 473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1005)
[M::mem_pestat] mean and std.dev: (297.14, 137.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1271)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682476 reads in 207.925 CPU sec, 7.034 real sec
[M::mem_process_seqs] Processed 682286 reads in 122.411 CPU sec, 4.116 real sec
[M::process] read 681812 sequences (100000118 bp) in 2.507 CPU sec, 2.779 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 281558, 10, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 349, 562)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1340)
[M::mem_pestat] mean and std.dev: (354.87, 199.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1729)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 323, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 954)
[M::mem_pestat] mean and std.dev: (342.68, 166.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1203)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 1218, 2575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7457)
[M::mem_pestat] mean and std.dev: (1280.20, 1330.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9898)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 298, 851)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2103)
[M::mem_pestat] mean and std.dev: (454.40, 323.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2729)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 22, #reads = 1078319 mem = 536879317 peak = 928673792
[M::process] read 681312 sequences (100000246 bp) in 2.583 CPU sec, 2.912 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 282333, 14, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 258, 520)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1096)
[M::mem_pestat] mean and std.dev: (324.66, 217.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1384)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 326, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 972)
[M::mem_pestat] mean and std.dev: (346.13, 169.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1227)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (124, 4054, 4054)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11914)
[M::mem_pestat] mean and std.dev: (2158.64, 2003.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 15844)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 269, 397)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 737)
[M::mem_pestat] mean and std.dev: (284.11, 121.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 907)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681804 reads in 186.266 CPU sec, 6.224 real sec
[M::mem_process_seqs] Processed 681812 reads in 121.840 CPU sec, 4.074 real sec
[M::process] read 680794 sequences (100000031 bp) in 2.527 CPU sec, 2.880 real sec...
sorting block 23, #reads = 1078275 mem = 536878162 peak = 928673792
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 282079, 17, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 307, 418)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 912)
[M::mem_pestat] mean and std.dev: (269.22, 103.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1159)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 330, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 975)
[M::mem_pestat] mean and std.dev: (348.95, 169.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1230)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (470, 626, 767)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1361)
[M::mem_pestat] mean and std.dev: (494.57, 257.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1658)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (261, 388, 738)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1692)
[M::mem_pestat] mean and std.dev: (524.68, 383.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2169)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680552 sequences (100000012 bp) in 2.508 CPU sec, 2.963 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 282167, 8, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 288, 548)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1212)
[M::mem_pestat] mean and std.dev: (292.63, 137.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1544)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 334, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 978)
[M::mem_pestat] mean and std.dev: (351.86, 170.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1233)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 297, 504)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1204)
[M::mem_pestat] mean and std.dev: (320.14, 222.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1554)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681312 reads in 188.370 CPU sec, 6.321 real sec
[M::mem_process_seqs] Processed 680794 reads in 123.589 CPU sec, 4.120 real sec
sorting block 24, #reads = 1078076 mem = 536879093 peak = 928673792
[M::process] read 680416 sequences (100000125 bp) in 2.595 CPU sec, 3.012 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 281421, 8, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 240, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 655)
[M::mem_pestat] mean and std.dev: (263.33, 97.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 805)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 336, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 985)
[M::mem_pestat] mean and std.dev: (354.05, 171.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1242)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 326, 664)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1528)
[M::mem_pestat] mean and std.dev: (359.00, 217.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1960)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680470 sequences (100000059 bp) in 2.376 CPU sec, 2.638 real sec...
sorting block 25, #reads = 1077552 mem = 536880219 peak = 928673792
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 281435, 6, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 347, 707)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1731)
[M::mem_pestat] mean and std.dev: (447.38, 388.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2243)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 338, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 984)
[M::mem_pestat] mean and std.dev: (354.75, 170.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1240)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 416, 642)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1412)
[M::mem_pestat] mean and std.dev: (445.79, 318.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1797)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680552 reads in 186.687 CPU sec, 6.303 real sec
[M::mem_process_seqs] Processed 680416 reads in 123.001 CPU sec, 4.160 real sec
[M::process] read 679998 sequences (100000258 bp) in 2.654 CPU sec, 2.886 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 282255, 12, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 317, 741)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1847)
[M::mem_pestat] mean and std.dev: (384.92, 291.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2400)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 336, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 977)
[M::mem_pestat] mean and std.dev: (353.40, 170.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1231)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1590, 1590, 2647)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4761)
[M::mem_pestat] mean and std.dev: (2015.58, 694.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5818)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 341, 406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 796)
[M::mem_pestat] mean and std.dev: (330.23, 147.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 991)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 26, #reads = 1077185 mem = 536884275 peak = 928673792
[M::process] read 680210 sequences (100000079 bp) in 2.410 CPU sec, 2.849 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 281080, 26, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (268, 504, 1285)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3319)
[M::mem_pestat] mean and std.dev: (797.42, 870.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4336)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 338, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 979)
[M::mem_pestat] mean and std.dev: (354.74, 169.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1233)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (432, 952, 1156)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2604)
[M::mem_pestat] mean and std.dev: (718.13, 610.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3328)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 353, 499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1083)
[M::mem_pestat] mean and std.dev: (349.40, 146.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1375)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680470 reads in 187.445 CPU sec, 6.279 real sec
[M::mem_process_seqs] Processed 679998 reads in 124.037 CPU sec, 4.184 real sec
[M::process] read 679828 sequences (100000139 bp) in 2.472 CPU sec, 2.849 real sec...
sorting block 27, #reads = 1076700 mem = 536880092 peak = 928673792
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 281709, 7, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 342, 564)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1216)
[M::mem_pestat] mean and std.dev: (343.67, 206.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1542)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 334, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 963)
[M::mem_pestat] mean and std.dev: (350.73, 166.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1212)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 379, 706)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1652)
[M::mem_pestat] mean and std.dev: (391.88, 230.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2125)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 679638 sequences (100000090 bp) in 2.471 CPU sec, 2.962 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 280946, 10, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 275, 710)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1778)
[M::mem_pestat] mean and std.dev: (433.40, 319.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2312)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 338, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 971)
[M::mem_pestat] mean and std.dev: (354.34, 168.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1222)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 633, 633)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1539)
[M::mem_pestat] mean and std.dev: (416.00, 235.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1992)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 290, 396)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 778)
[M::mem_pestat] mean and std.dev: (303.13, 120.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 969)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680210 reads in 190.181 CPU sec, 6.317 real sec
[M::mem_process_seqs] Processed 679828 reads in 123.671 CPU sec, 4.151 real sec
[M::process] read 679628 sequences (100000171 bp) in 2.166 CPU sec, 2.356 real sec...
sorting block 28, #reads = 1075270 mem = 536879512 peak = 928673792
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 280836, 11, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 364, 819)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1977)
[M::mem_pestat] mean and std.dev: (452.57, 332.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2556)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 338, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 969)
[M::mem_pestat] mean and std.dev: (354.24, 167.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1219)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 585, 2853)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8259)
[M::mem_pestat] mean and std.dev: (1467.45, 1658.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10962)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 289, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 856)
[M::mem_pestat] mean and std.dev: (297.82, 126.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1066)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 679456 sequences (100000042 bp) in 2.142 CPU sec, 2.436 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 280647, 14, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 252, 571)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1397)
[M::mem_pestat] mean and std.dev: (274.10, 189.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1810)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 336, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 959)
[M::mem_pestat] mean and std.dev: (352.75, 166.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1206)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 256, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (172, 312)
[M::mem_pestat] mean and std.dev: (249.00, 12.12)
[M::mem_pestat] low and high boundaries for proper pairs: (144, 340)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 382, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 831)
[M::mem_pestat] mean and std.dev: (337.47, 143.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1025)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 679638 reads in 190.207 CPU sec, 6.363 real sec
sorting block 29, #reads = 1075698 mem = 536880075 peak = 928673792
[M::mem_process_seqs] Processed 679628 reads in 123.852 CPU sec, 4.113 real sec
[M::process] read 679384 sequences (100000249 bp) in 2.458 CPU sec, 2.657 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 281294, 10, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 375, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 919)
[M::mem_pestat] mean and std.dev: (343.71, 196.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1163)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 337, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 969)
[M::mem_pestat] mean and std.dev: (354.48, 168.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1219)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (24, 345, 605)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1767)
[M::mem_pestat] mean and std.dev: (467.50, 456.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2348)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 520, 876)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2120)
[M::mem_pestat] mean and std.dev: (658.16, 492.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2742)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 679234 sequences (100000251 bp) in 2.754 CPU sec, 3.016 real sec...
sorting block 30, #reads = 1075001 mem = 536879933 peak = 928673792
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 281638, 17, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 259, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 807)
[M::mem_pestat] mean and std.dev: (271.00, 156.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1028)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 340, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 967)
[M::mem_pestat] mean and std.dev: (355.56, 167.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1216)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 134, 2029)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5819)
[M::mem_pestat] mean and std.dev: (889.00, 1173.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7714)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 314, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 898)
[M::mem_pestat] mean and std.dev: (330.22, 144.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1123)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 679456 reads in 187.843 CPU sec, 6.290 real sec
[M::mem_process_seqs] Processed 679384 reads in 122.616 CPU sec, 4.170 real sec
[M::process] read 679566 sequences (100000290 bp) in 2.658 CPU sec, 3.236 real sec...
sorting block 31, #reads = 1076647 mem = 536878656 peak = 928673792
[M::process] read 679410 sequences (100000261 bp) in 2.136 CPU sec, 2.444 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 281495, 5, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (131, 251, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 656)
[M::mem_pestat] mean and std.dev: (228.43, 110.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 831)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 333, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 952)
[M::mem_pestat] mean and std.dev: (350.16, 165.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1197)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 354, 553)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1219)
[M::mem_pestat] mean and std.dev: (344.76, 193.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1552)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 679566 reads in 103.586 CPU sec, 3.622 real sec
[M::process] read 679548 sequences (100000073 bp) in 2.572 CPU sec, 2.864 real sec...
sorting block 32, #reads = 1074560 mem = 536880349 peak = 928673792
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 280832, 11, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 237, 495)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1109)
[M::mem_pestat] mean and std.dev: (303.47, 172.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1416)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 333, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 950)
[M::mem_pestat] mean and std.dev: (350.24, 165.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1194)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (482, 713, 821)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1499)
[M::mem_pestat] mean and std.dev: (597.70, 322.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1889)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 293, 492)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1038)
[M::mem_pestat] mean and std.dev: (312.33, 168.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1311)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 280815, 11, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 269, 534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1162)
[M::mem_pestat] mean and std.dev: (366.50, 246.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1476)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 336, 464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 954)
[M::mem_pestat] mean and std.dev: (351.98, 165.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1199)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 1083, 1248)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3338)
[M::mem_pestat] mean and std.dev: (756.27, 520.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4383)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 327, 672)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1596)
[M::mem_pestat] mean and std.dev: (350.94, 283.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2058)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 679410 reads in 101.685 CPU sec, 3.471 real sec
[M::mem_process_seqs] Processed 679234 reads in 307.377 CPU sec, 10.626 real sec
[M::process] read 679732 sequences (100000159 bp) in 2.384 CPU sec, 2.668 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 281655, 7, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 253, 501)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1121)
[M::mem_pestat] mean and std.dev: (269.31, 140.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1431)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 334, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 953)
[M::mem_pestat] mean and std.dev: (350.78, 165.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1198)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 318, 420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 778)
[M::mem_pestat] mean and std.dev: (313.83, 120.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 957)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 33, #reads = 1074390 mem = 536880375 peak = 928673792
[M::process] read 679878 sequences (100000085 bp) in 2.328 CPU sec, 2.728 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 281945, 13, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 307, 795)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1901)
[M::mem_pestat] mean and std.dev: (529.22, 434.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2454)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 332, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 952)
[M::mem_pestat] mean and std.dev: (350.15, 166.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1197)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 251, 594)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1368)
[M::mem_pestat] mean and std.dev: (339.00, 156.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1755)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 295, 533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1215)
[M::mem_pestat] mean and std.dev: (327.64, 195.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1556)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 679548 reads in 182.709 CPU sec, 6.245 real sec
[M::mem_process_seqs] Processed 679732 reads in 116.810 CPU sec, 4.054 real sec
[M::process] read 679722 sequences (100000069 bp) in 2.180 CPU sec, 2.378 real sec...
sorting block 34, #reads = 1074920 mem = 536878920 peak = 928673792
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 281447, 19, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 217, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 842)
[M::mem_pestat] mean and std.dev: (213.33, 91.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1076)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 331, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 945)
[M::mem_pestat] mean and std.dev: (347.97, 164.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1188)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (679, 759, 2341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5665)
[M::mem_pestat] mean and std.dev: (1161.53, 874.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7327)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (263, 307, 525)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1049)
[M::mem_pestat] mean and std.dev: (338.24, 178.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1311)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 679954 sequences (100000088 bp) in 2.597 CPU sec, 2.850 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 281719, 10, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 261, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 936)
[M::mem_pestat] mean and std.dev: (303.05, 134.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1185)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 333, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 955)
[M::mem_pestat] mean and std.dev: (350.64, 166.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1201)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (761, 2470, 4056)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10646)
[M::mem_pestat] mean and std.dev: (2481.60, 1865.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13941)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 392, 536)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1230)
[M::mem_pestat] mean and std.dev: (360.67, 186.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1577)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 679878 reads in 184.029 CPU sec, 6.099 real sec
[M::mem_process_seqs] Processed 679722 reads in 117.251 CPU sec, 3.992 real sec
[M::process] read 679882 sequences (100000157 bp) in 2.073 CPU sec, 2.216 real sec...
sorting block 35, #reads = 1075428 mem = 536876962 peak = 928673792
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 281434, 23, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 304, 537)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1181)
[M::mem_pestat] mean and std.dev: (319.84, 144.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1503)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 332, 460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 948)
[M::mem_pestat] mean and std.dev: (349.10, 165.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1192)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (121, 220, 1843)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5287)
[M::mem_pestat] mean and std.dev: (967.00, 958.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7009)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (294, 425, 537)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1023)
[M::mem_pestat] mean and std.dev: (392.23, 155.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1266)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 679756 sequences (100000106 bp) in 2.437 CPU sec, 2.752 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281569, 7, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 226, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 525)
[M::mem_pestat] mean and std.dev: (244.65, 99.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 643)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 332, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 957)
[M::mem_pestat] mean and std.dev: (350.80, 167.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1204)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (321, 427, 592)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1134)
[M::mem_pestat] mean and std.dev: (398.91, 208.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1405)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 679954 reads in 182.424 CPU sec, 6.138 real sec
sorting block 36, #reads = 1075023 mem = 536877650 peak = 928673792
[M::mem_process_seqs] Processed 679882 reads in 118.155 CPU sec, 4.007 real sec
[M::process] read 683766 sequences (100000111 bp) in 2.451 CPU sec, 2.647 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 281438, 9, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 237, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 649)
[M::mem_pestat] mean and std.dev: (244.52, 91.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 804)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 333, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 957)
[M::mem_pestat] mean and std.dev: (350.75, 167.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1204)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 376, 1113)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2885)
[M::mem_pestat] mean and std.dev: (598.30, 633.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3771)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 37, #reads = 1075276 mem = 536878178 peak = 974811136
[M::process] read 683900 sequences (100000244 bp) in 2.714 CPU sec, 3.084 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 282956, 18, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 343, 516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1186)
[M::mem_pestat] mean and std.dev: (380.55, 244.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1521)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 311, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 926)
[M::mem_pestat] mean and std.dev: (332.36, 163.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1168)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 1096, 2054)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5806)
[M::mem_pestat] mean and std.dev: (1082.89, 906.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7682)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 320, 377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 787)
[M::mem_pestat] mean and std.dev: (273.38, 122.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 992)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 679756 reads in 186.170 CPU sec, 6.293 real sec
[M::process] read 683490 sequences (100000187 bp) in 1.891 CPU sec, 2.117 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 282268, 6, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 213, 502)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1190)
[M::mem_pestat] mean and std.dev: (276.46, 165.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1534)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 309, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 927)
[M::mem_pestat] mean and std.dev: (331.31, 163.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1170)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 337, 528)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1202)
[M::mem_pestat] mean and std.dev: (343.02, 226.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1539)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683900 reads in 105.374 CPU sec, 3.490 real sec
[M::process] read 682890 sequences (100000119 bp) in 2.170 CPU sec, 2.258 real sec...
sorting block 38, #reads = 1075284 mem = 536877663 peak = 974811136
[M::mem_process_seqs] Processed 683766 reads in 285.345 CPU sec, 9.638 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 283213, 8, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 218, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1007)
[M::mem_pestat] mean and std.dev: (330.02, 240.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1294)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 313, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 935)
[M::mem_pestat] mean and std.dev: (334.15, 164.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1180)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 319, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 720)
[M::mem_pestat] mean and std.dev: (299.19, 138.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 894)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 283172, 8, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 355, 789)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2005)
[M::mem_pestat] mean and std.dev: (444.76, 336.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2613)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 315, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 926)
[M::mem_pestat] mean and std.dev: (335.15, 163.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1167)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 296, 635)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1421)
[M::mem_pestat] mean and std.dev: (428.40, 302.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1814)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682744 sequences (100000070 bp) in 2.840 CPU sec, 3.305 real sec...
sorting block 39, #reads = 1076536 mem = 536878026 peak = 974811136
[M::mem_process_seqs] Processed 683490 reads in 197.724 CPU sec, 6.663 real sec
[M::mem_process_seqs] Processed 682890 reads in 119.079 CPU sec, 3.981 real sec
[M::process] read 682676 sequences (100000081 bp) in 2.687 CPU sec, 3.137 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 282707, 14, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 246, 493)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1101)
[M::mem_pestat] mean and std.dev: (288.66, 140.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1405)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 316, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 933)
[M::mem_pestat] mean and std.dev: (336.20, 163.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1176)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (356, 1224, 6413)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 18527)
[M::mem_pestat] mean and std.dev: (2604.29, 3030.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 24584)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 301, 646)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1572)
[M::mem_pestat] mean and std.dev: (365.92, 282.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2035)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 40, #reads = 1078210 mem = 536878297 peak = 974811136
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 283003, 8, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 387, 577)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1265)
[M::mem_pestat] mean and std.dev: (336.23, 166.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1609)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 317, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 936)
[M::mem_pestat] mean and std.dev: (337.38, 164.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1180)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 277, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1013)
[M::mem_pestat] mean and std.dev: (360.15, 225.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1285)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682232 sequences (100000288 bp) in 2.602 CPU sec, 2.911 real sec...
[M::mem_process_seqs] Processed 682744 reads in 182.168 CPU sec, 6.115 real sec
[M::mem_process_seqs] Processed 682676 reads in 121.373 CPU sec, 4.120 real sec
[M::process] read 681676 sequences (100000206 bp) in 2.570 CPU sec, 2.942 real sec...
sorting block 41, #reads = 1077818 mem = 536879002 peak = 974811136
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 282164, 22, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 266, 491)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1069)
[M::mem_pestat] mean and std.dev: (346.27, 213.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1358)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 321, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 944)
[M::mem_pestat] mean and std.dev: (339.80, 164.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1190)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (731, 1857, 4550)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12188)
[M::mem_pestat] mean and std.dev: (2375.36, 1703.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16007)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (264, 344, 534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1074)
[M::mem_pestat] mean and std.dev: (372.65, 179.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1344)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 282386, 18, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 263, 596)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1450)
[M::mem_pestat] mean and std.dev: (306.89, 180.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1877)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 325, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 956)
[M::mem_pestat] mean and std.dev: (344.21, 167.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1205)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 790, 1475)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3949)
[M::mem_pestat] mean and std.dev: (845.11, 801.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5186)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 374, 679)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1593)
[M::mem_pestat] mean and std.dev: (402.26, 246.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2050)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681526 sequences (100000098 bp) in 2.414 CPU sec, 2.940 real sec...
[M::mem_process_seqs] Processed 682232 reads in 181.159 CPU sec, 6.162 real sec
[M::mem_process_seqs] Processed 681676 reads in 117.396 CPU sec, 4.051 real sec
sorting block 42, #reads = 1077786 mem = 536878617 peak = 974811136
[M::process] read 681116 sequences (100000274 bp) in 2.837 CPU sec, 3.174 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 282300, 13, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 232, 401)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 871)
[M::mem_pestat] mean and std.dev: (282.47, 161.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1106)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 327, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 965)
[M::mem_pestat] mean and std.dev: (345.97, 168.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1217)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (587, 634, 1447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3167)
[M::mem_pestat] mean and std.dev: (834.77, 550.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4027)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 256, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 550)
[M::mem_pestat] mean and std.dev: (240.35, 88.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 674)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681526 reads in 105.279 CPU sec, 3.783 real sec
[M::process] read 680660 sequences (100000168 bp) in 2.661 CPU sec, 3.166 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 282269, 17, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 217, 611)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1509)
[M::mem_pestat] mean and std.dev: (320.68, 260.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1958)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 331, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 979)
[M::mem_pestat] mean and std.dev: (350.48, 170.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1235)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (746, 876, 2436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5816)
[M::mem_pestat] mean and std.dev: (1205.47, 943.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7506)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 273, 400)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 814)
[M::mem_pestat] mean and std.dev: (233.78, 77.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1021)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 43, #reads = 1075932 mem = 536884726 peak = 974811136
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 281523, 12, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 314, 672)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1586)
[M::mem_pestat] mean and std.dev: (388.08, 307.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2043)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 334, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 984)
[M::mem_pestat] mean and std.dev: (352.93, 171.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1241)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (501, 860, 1062)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2184)
[M::mem_pestat] mean and std.dev: (675.64, 343.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2745)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 319, 388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 774)
[M::mem_pestat] mean and std.dev: (268.31, 105.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 967)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680662 sequences (100000256 bp) in 2.567 CPU sec, 2.933 real sec...
[M::mem_process_seqs] Processed 680660 reads in 103.108 CPU sec, 3.418 real sec
sorting block 44, #reads = 1076993 mem = 536880794 peak = 974811136
[M::mem_process_seqs] Processed 681116 reads in 282.859 CPU sec, 9.419 real sec
[M::process] read 680536 sequences (100000169 bp) in 2.786 CPU sec, 3.041 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 281859, 17, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 297, 407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 879)
[M::mem_pestat] mean and std.dev: (323.98, 185.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1115)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 335, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 983)
[M::mem_pestat] mean and std.dev: (353.99, 171.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1239)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (469, 747, 1800)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4462)
[M::mem_pestat] mean and std.dev: (804.47, 703.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5793)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 384, 569)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1259)
[M::mem_pestat] mean and std.dev: (315.15, 161.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1604)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 282251, 12, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (267, 373, 822)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1932)
[M::mem_pestat] mean and std.dev: (425.72, 249.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2487)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 335, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 982)
[M::mem_pestat] mean and std.dev: (353.46, 170.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1238)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (794, 851, 859)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (664, 989)
[M::mem_pestat] mean and std.dev: (844.00, 20.60)
[M::mem_pestat] low and high boundaries for proper pairs: (599, 1054)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 317, 412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 844)
[M::mem_pestat] mean and std.dev: (296.30, 156.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1060)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680518 sequences (100000082 bp) in 2.931 CPU sec, 3.357 real sec...
[M::mem_process_seqs] Processed 680662 reads in 186.455 CPU sec, 6.076 real sec
[M::mem_process_seqs] Processed 680536 reads in 125.272 CPU sec, 4.117 real sec
sorting block 45, #reads = 1076021 mem = 536878486 peak = 974811136
[M::process] read 680476 sequences (100000120 bp) in 2.518 CPU sec, 2.728 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 281670, 17, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 216, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 785)
[M::mem_pestat] mean and std.dev: (222.07, 113.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 998)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 335, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 988)
[M::mem_pestat] mean and std.dev: (353.62, 170.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1246)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1067, 1429, 1442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (317, 2192)
[M::mem_pestat] mean and std.dev: (1199.55, 324.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2567)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 494, 745)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1731)
[M::mem_pestat] mean and std.dev: (518.79, 320.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2224)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 46, #reads = 1076092 mem = 536879706 peak = 978825216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 281862, 10, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 355, 549)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1173)
[M::mem_pestat] mean and std.dev: (342.34, 197.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1485)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 335, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 985)
[M::mem_pestat] mean and std.dev: (353.81, 170.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1242)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (275, 762, 3165)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8945)
[M::mem_pestat] mean and std.dev: (1822.67, 2575.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12125)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 297, 570)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1350)
[M::mem_pestat] mean and std.dev: (357.22, 294.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1740)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680266 sequences (100000100 bp) in 2.734 CPU sec, 3.084 real sec...
[M::mem_process_seqs] Processed 680518 reads in 187.540 CPU sec, 6.155 real sec
[M::mem_process_seqs] Processed 680476 reads in 123.926 CPU sec, 4.030 real sec
[M::process] read 680482 sequences (100000020 bp) in 3.019 CPU sec, 3.366 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 281233, 7, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 243, 573)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1335)
[M::mem_pestat] mean and std.dev: (312.00, 233.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1716)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 334, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 974)
[M::mem_pestat] mean and std.dev: (353.02, 170.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1227)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 463, 473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 913)
[M::mem_pestat] mean and std.dev: (371.41, 168.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1133)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 47, #reads = 1076642 mem = 536876784 peak = 978825216
[M::process] read 680220 sequences (100000300 bp) in 2.516 CPU sec, 2.829 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 281075, 10, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 360, 420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 830)
[M::mem_pestat] mean and std.dev: (297.05, 113.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1035)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 331, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 969)
[M::mem_pestat] mean and std.dev: (350.60, 169.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1221)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1046, 1596, 2103)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4217)
[M::mem_pestat] mean and std.dev: (1192.38, 707.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5274)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 357, 518)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1058)
[M::mem_pestat] mean and std.dev: (410.39, 237.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1361)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680266 reads in 186.679 CPU sec, 6.109 real sec
[M::mem_process_seqs] Processed 680482 reads in 124.421 CPU sec, 4.040 real sec
sorting block 48, #reads = 1076524 mem = 536886288 peak = 978825216
[M::process] read 680232 sequences (100000041 bp) in 2.796 CPU sec, 3.003 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 281801, 8, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 290, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 706)
[M::mem_pestat] mean and std.dev: (284.08, 121.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 877)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 332, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 973)
[M::mem_pestat] mean and std.dev: (352.05, 169.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1226)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 280, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 968)
[M::mem_pestat] mean and std.dev: (293.76, 161.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1228)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680500 sequences (100000289 bp) in 2.209 CPU sec, 2.655 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 281181, 10, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 190, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 792)
[M::mem_pestat] mean and std.dev: (267.00, 180.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1005)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 332, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 976)
[M::mem_pestat] mean and std.dev: (351.88, 169.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1230)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (103, 129, 640)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1714)
[M::mem_pestat] mean and std.dev: (294.40, 250.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2251)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 275, 596)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1380)
[M::mem_pestat] mean and std.dev: (282.83, 134.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1772)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680220 reads in 183.797 CPU sec, 6.038 real sec
[M::mem_process_seqs] Processed 680232 reads in 122.222 CPU sec, 4.009 real sec
sorting block 49, #reads = 1075853 mem = 536877556 peak = 978825216
[M::process] read 680508 sequences (100000054 bp) in 3.070 CPU sec, 3.333 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 281168, 12, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 307, 498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1028)
[M::mem_pestat] mean and std.dev: (330.89, 170.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1293)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 329, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 965)
[M::mem_pestat] mean and std.dev: (348.86, 168.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1216)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 573, 2940)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8438)
[M::mem_pestat] mean and std.dev: (1112.83, 1243.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11187)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 325, 689)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1613)
[M::mem_pestat] mean and std.dev: (459.00, 357.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2075)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680448 sequences (100000108 bp) in 2.377 CPU sec, 2.722 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 281591, 6, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 221, 408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 932)
[M::mem_pestat] mean and std.dev: (261.42, 170.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1194)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 327, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 950)
[M::mem_pestat] mean and std.dev: (346.48, 167.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1196)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (264, 323, 737)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1683)
[M::mem_pestat] mean and std.dev: (477.93, 351.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2156)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680500 reads in 186.795 CPU sec, 6.070 real sec
sorting block 50, #reads = 1076367 mem = 536879478 peak = 978825216
[M::mem_process_seqs] Processed 680508 reads in 122.193 CPU sec, 3.938 real sec
[M::process] read 680236 sequences (100000151 bp) in 2.729 CPU sec, 2.908 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 281549, 11, 84)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 247, 477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1081)
[M::mem_pestat] mean and std.dev: (334.07, 203.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1383)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 328, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 960)
[M::mem_pestat] mean and std.dev: (348.52, 168.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1209)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 1088, 3020)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8666)
[M::mem_pestat] mean and std.dev: (1571.36, 1642.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11489)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 362, 484)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1018)
[M::mem_pestat] mean and std.dev: (351.88, 184.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1285)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 51, #reads = 1075954 mem = 536880351 peak = 1021194240
[M::process] read 680480 sequences (100000300 bp) in 2.604 CPU sec, 3.045 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281736, 8, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 360, 553)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1259)
[M::mem_pestat] mean and std.dev: (355.75, 206.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1612)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 331, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 961)
[M::mem_pestat] mean and std.dev: (349.73, 168.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1210)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 334, 679)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1535)
[M::mem_pestat] mean and std.dev: (386.11, 227.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1963)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680448 reads in 186.494 CPU sec, 6.112 real sec
[M::mem_process_seqs] Processed 680236 reads in 121.352 CPU sec, 3.940 real sec
[M::process] read 680076 sequences (100000163 bp) in 2.805 CPU sec, 3.013 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 281886, 28, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 429, 918)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2224)
[M::mem_pestat] mean and std.dev: (577.62, 472.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2877)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 328, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 948)
[M::mem_pestat] mean and std.dev: (346.38, 165.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1193)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (57, 678, 1522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4452)
[M::mem_pestat] mean and std.dev: (695.11, 741.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5917)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 244, 489)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1073)
[M::mem_pestat] mean and std.dev: (299.98, 148.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1365)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 52, #reads = 1075430 mem = 536879294 peak = 1021194240
[M::process] read 680008 sequences (100000189 bp) in 2.750 CPU sec, 3.104 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 280956, 8, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 195, 387)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 839)
[M::mem_pestat] mean and std.dev: (258.14, 156.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1065)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 331, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 953)
[M::mem_pestat] mean and std.dev: (349.18, 166.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1199)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 301, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (51, 521)
[M::mem_pestat] mean and std.dev: (278.42, 84.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 616)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680480 reads in 188.462 CPU sec, 6.083 real sec
[M::mem_process_seqs] Processed 680076 reads in 121.868 CPU sec, 3.891 real sec
[M::process] read 679664 sequences (100000109 bp) in 2.444 CPU sec, 2.577 real sec...
sorting block 53, #reads = 1075893 mem = 536876746 peak = 1021194240
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 281133, 8, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 254, 402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 820)
[M::mem_pestat] mean and std.dev: (269.39, 102.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1029)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 332, 464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 960)
[M::mem_pestat] mean and std.dev: (350.98, 168.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1208)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 263, 412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 846)
[M::mem_pestat] mean and std.dev: (275.79, 124.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1063)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 679766 sequences (100000038 bp) in 2.631 CPU sec, 2.976 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 281350, 22, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 260, 404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 890)
[M::mem_pestat] mean and std.dev: (297.57, 181.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1133)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 335, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 967)
[M::mem_pestat] mean and std.dev: (353.29, 168.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1217)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 837, 1437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3873)
[M::mem_pestat] mean and std.dev: (796.71, 593.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5091)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 262, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 736)
[M::mem_pestat] mean and std.dev: (251.75, 107.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 919)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680008 reads in 183.909 CPU sec, 5.978 real sec
[M::mem_process_seqs] Processed 679664 reads in 119.455 CPU sec, 3.874 real sec
[M::process] read 679672 sequences (100000132 bp) in 2.112 CPU sec, 2.255 real sec...
sorting block 54, #reads = 1074318 mem = 536876087 peak = 1021194240
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 282188, 8, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 288, 527)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1167)
[M::mem_pestat] mean and std.dev: (305.57, 174.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1487)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 335, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 959)
[M::mem_pestat] mean and std.dev: (352.72, 168.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1206)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 280, 417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 857)
[M::mem_pestat] mean and std.dev: (283.36, 144.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1077)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 55, #reads = 1075796 mem = 536878218 peak = 1021194240
[M::process] read 680224 sequences (100000172 bp) in 3.189 CPU sec, 3.549 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 281383, 9, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 335, 639)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1603)
[M::mem_pestat] mean and std.dev: (413.19, 364.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2085)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 333, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 952)
[M::mem_pestat] mean and std.dev: (350.89, 167.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1197)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (260, 381, 560)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1160)
[M::mem_pestat] mean and std.dev: (367.17, 165.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1460)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 679766 reads in 183.256 CPU sec, 5.972 real sec
[M::mem_process_seqs] Processed 679672 reads in 120.066 CPU sec, 3.886 real sec
[M::process] read 682976 sequences (100000218 bp) in 2.219 CPU sec, 2.425 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 281975, 3, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 216, 476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1142)
[M::mem_pestat] mean and std.dev: (298.45, 208.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1475)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 332, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 951)
[M::mem_pestat] mean and std.dev: (349.82, 167.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1196)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 371, 894)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2334)
[M::mem_pestat] mean and std.dev: (549.59, 489.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3054)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 56, #reads = 1076090 mem = 536883449 peak = 1021194240
[M::process] read 683314 sequences (100000255 bp) in 2.524 CPU sec, 2.827 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 282630, 12, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 308, 641)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1521)
[M::mem_pestat] mean and std.dev: (369.51, 310.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1961)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 316, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 938)
[M::mem_pestat] mean and std.dev: (337.86, 166.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1183)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 468, 3884)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11384)
[M::mem_pestat] mean and std.dev: (1866.42, 2801.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 15134)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 307, 460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 966)
[M::mem_pestat] mean and std.dev: (315.08, 155.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1219)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680224 reads in 184.368 CPU sec, 5.998 real sec
[M::mem_process_seqs] Processed 682976 reads in 122.859 CPU sec, 3.958 real sec
[M::process] read 682840 sequences (100000204 bp) in 2.133 CPU sec, 2.270 real sec...
sorting block 57, #reads = 1074877 mem = 536878121 peak = 1021194240
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 282190, 13, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 369, 692)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1652)
[M::mem_pestat] mean and std.dev: (424.65, 281.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2132)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 315, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 948)
[M::mem_pestat] mean and std.dev: (338.02, 168.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1197)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (323, 957, 1684)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4406)
[M::mem_pestat] mean and std.dev: (1052.08, 808.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5767)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 360, 613)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1355)
[M::mem_pestat] mean and std.dev: (422.57, 272.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1726)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682574 sequences (100000145 bp) in 2.474 CPU sec, 2.784 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 282735, 8, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 217, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1115)
[M::mem_pestat] mean and std.dev: (287.54, 183.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1439)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 317, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 953)
[M::mem_pestat] mean and std.dev: (340.03, 168.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1203)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 276, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 921)
[M::mem_pestat] mean and std.dev: (255.00, 119.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1177)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683314 reads in 180.155 CPU sec, 5.868 real sec
[M::process] read 682260 sequences (100000144 bp) in 2.151 CPU sec, 2.231 real sec...
[M::mem_process_seqs] Processed 682840 reads in 119.076 CPU sec, 3.866 real sec
sorting block 58, #reads = 1077551 mem = 536889593 peak = 1021194240
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 283013, 5, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 237, 428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 974)
[M::mem_pestat] mean and std.dev: (254.91, 139.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1247)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 320, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 955)
[M::mem_pestat] mean and std.dev: (342.25, 169.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1205)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 332, 484)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1028)
[M::mem_pestat] mean and std.dev: (319.25, 169.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1300)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682242 sequences (100000178 bp) in 2.625 CPU sec, 3.020 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 282737, 8, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 365, 1121)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2851)
[M::mem_pestat] mean and std.dev: (432.85, 305.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3716)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 322, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 959)
[M::mem_pestat] mean and std.dev: (343.74, 169.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1210)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 319, 603)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1371)
[M::mem_pestat] mean and std.dev: (364.54, 217.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1755)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682574 reads in 180.103 CPU sec, 5.904 real sec
[M::process] read 681700 sequences (100000011 bp) in 2.111 CPU sec, 2.170 real sec...
[M::mem_process_seqs] Processed 682260 reads in 118.671 CPU sec, 3.866 real sec
sorting block 59, #reads = 1078809 mem = 536878527 peak = 1021194240
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 282651, 15, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 448, 602)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1416)
[M::mem_pestat] mean and std.dev: (409.52, 209.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1823)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 323, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 959)
[M::mem_pestat] mean and std.dev: (343.64, 168.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1210)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (457, 1401, 2588)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6850)
[M::mem_pestat] mean and std.dev: (1195.23, 838.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8981)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (290, 343, 549)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1067)
[M::mem_pestat] mean and std.dev: (361.89, 207.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1326)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 60, #reads = 1079011 mem = 536883113 peak = 1021194240
[M::process] read 681270 sequences (100000250 bp) in 2.939 CPU sec, 3.389 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 282227, 8, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 259, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 645)
[M::mem_pestat] mean and std.dev: (265.14, 112.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 802)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 326, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 967)
[M::mem_pestat] mean and std.dev: (346.72, 170.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1220)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 281, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 609)
[M::mem_pestat] mean and std.dev: (260.85, 93.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 744)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682242 reads in 181.024 CPU sec, 5.944 real sec
[M::mem_process_seqs] Processed 681700 reads in 119.739 CPU sec, 3.890 real sec
[M::process] read 680996 sequences (100000161 bp) in 2.721 CPU sec, 2.965 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281835, 3, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 264, 377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 739)
[M::mem_pestat] mean and std.dev: (262.33, 94.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 920)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 327, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 957)
[M::mem_pestat] mean and std.dev: (346.78, 169.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1206)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (264, 400, 1100)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2772)
[M::mem_pestat] mean and std.dev: (440.44, 346.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3608)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 61, #reads = 1078319 mem = 536877057 peak = 1021194240
[M::process] read 681156 sequences (100000276 bp) in 2.423 CPU sec, 2.788 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 282258, 6, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 305, 830)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2106)
[M::mem_pestat] mean and std.dev: (497.20, 493.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2744)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 330, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 973)
[M::mem_pestat] mean and std.dev: (349.66, 170.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1227)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 205, 284)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 488)
[M::mem_pestat] mean and std.dev: (220.89, 52.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 590)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681270 reads in 184.958 CPU sec, 6.106 real sec
[M::process] read 680882 sequences (100000061 bp) in 2.603 CPU sec, 2.831 real sec...
sorting block 62, #reads = 1078691 mem = 536878335 peak = 1021194240
[M::process] read 680672 sequences (100000121 bp) in 2.037 CPU sec, 2.084 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 281572, 16, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 296, 388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 816)
[M::mem_pestat] mean and std.dev: (278.65, 154.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1030)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 332, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 984)
[M::mem_pestat] mean and std.dev: (352.25, 171.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1241)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1581, 1929, 2626)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4716)
[M::mem_pestat] mean and std.dev: (1746.50, 1035.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5888)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 314, 487)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1061)
[M::mem_pestat] mean and std.dev: (319.00, 160.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1348)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680882 reads in 99.290 CPU sec, 3.422 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281607, 8, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 258, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 713)
[M::mem_pestat] mean and std.dev: (280.98, 166.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 947)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 330, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 973)
[M::mem_pestat] mean and std.dev: (350.19, 170.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1227)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 282, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1052)
[M::mem_pestat] mean and std.dev: (276.16, 133.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1351)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681156 reads in 198.392 CPU sec, 7.260 real sec
sorting block 63, #reads = 1077377 mem = 536880956 peak = 1021194240
[M::process] read 680492 sequences (100000083 bp) in 2.843 CPU sec, 3.191 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 282188, 7, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 406, 499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1093)
[M::mem_pestat] mean and std.dev: (349.33, 179.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1390)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 336, 474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 994)
[M::mem_pestat] mean and std.dev: (355.35, 173.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1254)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (297, 341, 620)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1266)
[M::mem_pestat] mean and std.dev: (345.90, 134.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1589)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680996 reads in 414.966 CPU sec, 14.465 real sec
[M::mem_process_seqs] Processed 680672 reads in 116.527 CPU sec, 3.960 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 281842, 12, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 345, 761)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1867)
[M::mem_pestat] mean and std.dev: (384.31, 256.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2420)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 335, 473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 989)
[M::mem_pestat] mean and std.dev: (355.13, 173.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1247)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1217, 1875, 1875)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3191)
[M::mem_pestat] mean and std.dev: (1260.36, 663.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3915)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 319, 793)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2041)
[M::mem_pestat] mean and std.dev: (430.04, 387.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2665)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680330 sequences (100000091 bp) in 2.526 CPU sec, 3.052 real sec...
[M::mem_process_seqs] Processed 680492 reads in 99.691 CPU sec, 3.403 real sec
sorting block 64, #reads = 1077276 mem = 536877305 peak = 1021194240
[M::process] read 680570 sequences (100000166 bp) in 2.480 CPU sec, 2.807 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 281769, 18, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 287, 586)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1420)
[M::mem_pestat] mean and std.dev: (378.93, 273.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1837)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 335, 474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 994)
[M::mem_pestat] mean and std.dev: (356.14, 174.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1254)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (450, 1615, 2309)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6027)
[M::mem_pestat] mean and std.dev: (1521.28, 1464.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7886)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 275, 419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 813)
[M::mem_pestat] mean and std.dev: (308.98, 159.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1010)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 65, #reads = 1077579 mem = 536879136 peak = 1021194240
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 282229, 6, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 427, 660)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1572)
[M::mem_pestat] mean and std.dev: (413.61, 244.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2028)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 334, 474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 994)
[M::mem_pestat] mean and std.dev: (355.33, 174.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1254)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 342, 1849)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5145)
[M::mem_pestat] mean and std.dev: (916.77, 981.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6793)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680410 sequences (100000107 bp) in 2.425 CPU sec, 2.709 real sec...
[M::mem_process_seqs] Processed 680330 reads in 177.990 CPU sec, 5.923 real sec
[M::mem_process_seqs] Processed 680570 reads in 118.726 CPU sec, 3.929 real sec
[M::process] read 680752 sequences (100000182 bp) in 2.854 CPU sec, 3.137 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 281361, 8, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 197, 278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 504)
[M::mem_pestat] mean and std.dev: (199.59, 59.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 617)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 333, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 981)
[M::mem_pestat] mean and std.dev: (352.97, 171.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1237)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 281, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 878)
[M::mem_pestat] mean and std.dev: (320.32, 150.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1099)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 66, #reads = 1076932 mem = 536880447 peak = 1021194240
[M::process] read 680744 sequences (100000186 bp) in 2.143 CPU sec, 2.678 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 281870, 6, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 262, 394)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 838)
[M::mem_pestat] mean and std.dev: (251.50, 119.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1060)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 331, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 986)
[M::mem_pestat] mean and std.dev: (352.32, 172.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1244)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 308, 592)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1338)
[M::mem_pestat] mean and std.dev: (349.71, 224.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1711)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680410 reads in 181.131 CPU sec, 5.979 real sec
[M::mem_process_seqs] Processed 680752 reads in 118.374 CPU sec, 3.883 real sec
sorting block 67, #reads = 1077215 mem = 536880859 peak = 1021194240
[M::process] read 681000 sequences (100000160 bp) in 3.022 CPU sec, 3.413 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 281916, 5, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (292, 372, 1563)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4105)
[M::mem_pestat] mean and std.dev: (598.93, 573.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5376)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 329, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 976)
[M::mem_pestat] mean and std.dev: (350.12, 171.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1231)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 296, 403)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 807)
[M::mem_pestat] mean and std.dev: (295.54, 107.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1009)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 282107, 19, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 366, 484)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 988)
[M::mem_pestat] mean and std.dev: (382.63, 201.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1240)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 327, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 975)
[M::mem_pestat] mean and std.dev: (348.89, 171.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1230)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (298, 1668, 2284)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6256)
[M::mem_pestat] mean and std.dev: (1468.42, 1446.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8242)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 383, 646)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1500)
[M::mem_pestat] mean and std.dev: (415.92, 257.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1927)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681188 sequences (100000251 bp) in 2.503 CPU sec, 2.982 real sec...
[M::mem_process_seqs] Processed 680744 reads in 184.402 CPU sec, 6.040 real sec
[M::mem_process_seqs] Processed 681000 reads in 117.330 CPU sec, 3.808 real sec
sorting block 68, #reads = 1076048 mem = 536879300 peak = 1021194240
[M::process] read 680964 sequences (100000033 bp) in 2.784 CPU sec, 3.058 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 281735, 13, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 311, 518)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1144)
[M::mem_pestat] mean and std.dev: (323.54, 172.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1457)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 326, 464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 974)
[M::mem_pestat] mean and std.dev: (348.07, 171.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1229)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (324, 324, 1779)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4689)
[M::mem_pestat] mean and std.dev: (870.00, 937.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6144)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 318, 536)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1156)
[M::mem_pestat] mean and std.dev: (367.12, 203.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1466)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 69, #reads = 1077459 mem = 536883014 peak = 1021194240
[M::process] read 681284 sequences (100000085 bp) in 2.407 CPU sec, 2.597 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 281153, 18, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 405, 479)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 983)
[M::mem_pestat] mean and std.dev: (340.12, 155.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1235)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 325, 460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 960)
[M::mem_pestat] mean and std.dev: (346.89, 169.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1210)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 518, 1015)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2727)
[M::mem_pestat] mean and std.dev: (524.67, 487.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3583)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 412, 519)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1117)
[M::mem_pestat] mean and std.dev: (346.43, 158.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1416)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681188 reads in 186.011 CPU sec, 6.033 real sec
[M::mem_process_seqs] Processed 680964 reads in 118.915 CPU sec, 3.835 real sec
[M::process] read 681082 sequences (100000022 bp) in 2.314 CPU sec, 2.528 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281639, 7, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 343, 872)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2176)
[M::mem_pestat] mean and std.dev: (550.74, 503.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2828)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 323, 460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 964)
[M::mem_pestat] mean and std.dev: (345.70, 169.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1216)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 337, 529)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1207)
[M::mem_pestat] mean and std.dev: (344.52, 194.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1546)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 70, #reads = 1076396 mem = 536879494 peak = 1021194240
[M::process] read 681126 sequences (100000160 bp) in 2.931 CPU sec, 3.240 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281862, 5, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 331, 478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 994)
[M::mem_pestat] mean and std.dev: (320.77, 155.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1252)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 324, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 957)
[M::mem_pestat] mean and std.dev: (345.93, 169.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1206)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 325, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 933)
[M::mem_pestat] mean and std.dev: (300.38, 126.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1171)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681284 reads in 184.786 CPU sec, 6.024 real sec
[M::mem_process_seqs] Processed 681082 reads in 117.944 CPU sec, 3.806 real sec
[M::process] read 680856 sequences (100000161 bp) in 2.459 CPU sec, 2.736 real sec...
sorting block 71, #reads = 1076010 mem = 536880081 peak = 1021194240
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 282078, 5, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 342, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 910)
[M::mem_pestat] mean and std.dev: (334.48, 167.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1139)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 323, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 942)
[M::mem_pestat] mean and std.dev: (343.23, 166.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1186)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 312, 413)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (349.03, 183.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1082)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680500 sequences (100000200 bp) in 2.128 CPU sec, 2.312 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281733, 11, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 239, 411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 915)
[M::mem_pestat] mean and std.dev: (264.23, 147.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1167)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 325, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 952)
[M::mem_pestat] mean and std.dev: (345.44, 166.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1199)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (260, 1287, 7287)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 21341)
[M::mem_pestat] mean and std.dev: (2432.55, 3015.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 28368)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 248, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1013)
[M::mem_pestat] mean and std.dev: (288.16, 175.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1287)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681126 reads in 182.637 CPU sec, 5.941 real sec
[M::process] read 680464 sequences (100000047 bp) in 1.949 CPU sec, 2.065 real sec...
[M::mem_process_seqs] Processed 680856 reads in 119.251 CPU sec, 3.849 real sec
sorting block 72, #reads = 1076709 mem = 536880451 peak = 1021194240
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 281948, 19, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 258, 499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1061)
[M::mem_pestat] mean and std.dev: (356.91, 240.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1342)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 327, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 959)
[M::mem_pestat] mean and std.dev: (347.81, 168.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1208)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (757, 999, 1155)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1951)
[M::mem_pestat] mean and std.dev: (824.82, 443.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2601)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 333, 692)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1688)
[M::mem_pestat] mean and std.dev: (416.70, 309.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2186)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680290 sequences (100000114 bp) in 2.761 CPU sec, 3.413 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 281955, 4, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 219, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 717)
[M::mem_pestat] mean and std.dev: (249.25, 135.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 900)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 329, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 957)
[M::mem_pestat] mean and std.dev: (348.30, 167.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1205)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 293, 398)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 832)
[M::mem_pestat] mean and std.dev: (298.70, 151.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1049)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680500 reads in 180.944 CPU sec, 5.957 real sec
[M::mem_process_seqs] Processed 680464 reads in 118.987 CPU sec, 3.852 real sec
sorting block 73, #reads = 1075386 mem = 536878520 peak = 1021194240
[M::process] read 680274 sequences (100000180 bp) in 2.472 CPU sec, 2.711 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281880, 9, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 297, 486)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1100)
[M::mem_pestat] mean and std.dev: (291.88, 165.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1407)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 331, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 967)
[M::mem_pestat] mean and std.dev: (350.97, 169.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1218)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 296, 491)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1005)
[M::mem_pestat] mean and std.dev: (334.84, 190.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1262)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 74, #reads = 1076931 mem = 536884845 peak = 1033940992
[M::process] read 680258 sequences (100000275 bp) in 2.400 CPU sec, 2.759 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 282170, 11, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 309, 412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 818)
[M::mem_pestat] mean and std.dev: (315.05, 179.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1034)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 331, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 967)
[M::mem_pestat] mean and std.dev: (350.68, 169.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1218)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (118, 553, 1625)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4639)
[M::mem_pestat] mean and std.dev: (1149.73, 1363.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6606)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 317, 676)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1582)
[M::mem_pestat] mean and std.dev: (389.83, 257.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2035)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680290 reads in 179.193 CPU sec, 5.849 real sec
[M::mem_process_seqs] Processed 680274 reads in 118.117 CPU sec, 3.790 real sec
[M::process] read 680632 sequences (100000131 bp) in 2.333 CPU sec, 2.458 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 281859, 6, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 346, 492)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1146)
[M::mem_pestat] mean and std.dev: (351.26, 231.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1473)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 329, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 955)
[M::mem_pestat] mean and std.dev: (348.78, 168.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1202)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 278, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 948)
[M::mem_pestat] mean and std.dev: (308.95, 179.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1207)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 75, #reads = 1076217 mem = 536880619 peak = 1033940992
[M::process] read 686358 sequences (100000033 bp) in 2.857 CPU sec, 3.171 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 282119, 14, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 230, 428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 916)
[M::mem_pestat] mean and std.dev: (259.33, 140.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1160)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 327, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 950)
[M::mem_pestat] mean and std.dev: (346.20, 166.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1196)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1039, 1410, 2481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5365)
[M::mem_pestat] mean and std.dev: (1525.46, 789.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6807)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 209, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1121)
[M::mem_pestat] mean and std.dev: (262.03, 159.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1447)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680258 reads in 176.835 CPU sec, 5.754 real sec
[M::mem_process_seqs] Processed 680632 reads in 117.421 CPU sec, 3.786 real sec
[M::process] read 686314 sequences (100000164 bp) in 2.476 CPU sec, 2.697 real sec...
sorting block 76, #reads = 1076145 mem = 536878144 peak = 1033940992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 284027, 5, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 243, 482)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1126)
[M::mem_pestat] mean and std.dev: (275.73, 151.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1448)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 294, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 929)
[M::mem_pestat] mean and std.dev: (324.83, 169.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1176)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 396, 520)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1156)
[M::mem_pestat] mean and std.dev: (400.61, 224.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1474)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 685842 sequences (100000164 bp) in 2.411 CPU sec, 2.814 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 283990, 7, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 235, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 634)
[M::mem_pestat] mean and std.dev: (222.31, 94.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 792)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 292, 433)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 923)
[M::mem_pestat] mean and std.dev: (323.20, 167.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1168)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 468, 1189)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3101)
[M::mem_pestat] mean and std.dev: (628.63, 589.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4057)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 686358 reads in 201.827 CPU sec, 6.583 real sec
[M::process] read 684560 sequences (100000164 bp) in 2.003 CPU sec, 2.017 real sec...
[M::mem_process_seqs] Processed 686314 reads in 129.247 CPU sec, 4.219 real sec
sorting block 77, #reads = 1074256 mem = 536880203 peak = 1033940992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 284041, 9, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 266, 412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 904)
[M::mem_pestat] mean and std.dev: (277.48, 156.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1150)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 298, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 935)
[M::mem_pestat] mean and std.dev: (327.09, 167.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1183)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 318, 434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 838)
[M::mem_pestat] mean and std.dev: (324.67, 138.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1040)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 684226 sequences (100000245 bp) in 2.724 CPU sec, 3.086 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 283158, 11, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 336, 565)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1377)
[M::mem_pestat] mean and std.dev: (342.13, 233.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1783)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 304, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 953)
[M::mem_pestat] mean and std.dev: (332.21, 169.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1206)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (976, 1320, 1696)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3136)
[M::mem_pestat] mean and std.dev: (1086.60, 561.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3856)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (261, 335, 549)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1125)
[M::mem_pestat] mean and std.dev: (364.37, 168.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1413)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683906 sequences (100000225 bp) in 1.947 CPU sec, 1.969 real sec...
[M::mem_process_seqs] Processed 685842 reads in 193.851 CPU sec, 6.283 real sec
sorting block 78, #reads = 1076671 mem = 536880038 peak = 1037131776
[M::mem_process_seqs] Processed 684560 reads in 126.766 CPU sec, 4.096 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 282948, 8, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 241, 410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 894)
[M::mem_pestat] mean and std.dev: (303.73, 205.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1136)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 306, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 960)
[M::mem_pestat] mean and std.dev: (334.20, 169.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1215)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (271, 448, 532)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1054)
[M::mem_pestat] mean and std.dev: (379.71, 176.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1315)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 79, #reads = 1075737 mem = 536879621 peak = 1054408704
[M::process] read 685546 sequences (100000247 bp) in 2.578 CPU sec, 3.129 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 283195, 9, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 344, 1132)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3020)
[M::mem_pestat] mean and std.dev: (431.88, 372.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3964)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 308, 451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 959)
[M::mem_pestat] mean and std.dev: (335.60, 169.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1213)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 337, 639)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1431)
[M::mem_pestat] mean and std.dev: (421.98, 309.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1827)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684226 reads in 193.515 CPU sec, 6.294 real sec
[M::process] read 683578 sequences (100000235 bp) in 2.017 CPU sec, 2.033 real sec...
[M::mem_process_seqs] Processed 683906 reads in 126.296 CPU sec, 4.058 real sec
sorting block 80, #reads = 1076819 mem = 536879221 peak = 1054408704
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 284536, 15, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 267, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1036)
[M::mem_pestat] mean and std.dev: (292.26, 171.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1329)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 294, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 916)
[M::mem_pestat] mean and std.dev: (323.60, 165.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1158)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (779, 779, 2204)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5054)
[M::mem_pestat] mean and std.dev: (1084.69, 824.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6479)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 267, 400)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 886)
[M::mem_pestat] mean and std.dev: (281.32, 161.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1129)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683070 sequences (100000251 bp) in 2.892 CPU sec, 3.429 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 283532, 3, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 387, 628)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1488)
[M::mem_pestat] mean and std.dev: (283.54, 157.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1918)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 314, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 970)
[M::mem_pestat] mean and std.dev: (338.61, 169.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1227)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 342, 723)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1677)
[M::mem_pestat] mean and std.dev: (552.12, 438.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2307)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 685546 reads in 193.160 CPU sec, 6.246 real sec
[M::process] read 682962 sequences (100000022 bp) in 1.955 CPU sec, 1.973 real sec...
[M::mem_process_seqs] Processed 683578 reads in 125.350 CPU sec, 4.037 real sec
sorting block 81, #reads = 1078038 mem = 536880336 peak = 1054408704
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 282872, 4, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 273, 484)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1118)
[M::mem_pestat] mean and std.dev: (301.05, 155.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1435)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 316, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 974)
[M::mem_pestat] mean and std.dev: (340.65, 170.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1232)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (292, 395, 610)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1246)
[M::mem_pestat] mean and std.dev: (408.10, 206.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1564)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682318 sequences (100000027 bp) in 2.861 CPU sec, 3.211 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 282887, 16, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 262, 542)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1282)
[M::mem_pestat] mean and std.dev: (420.88, 376.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1928)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 318, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 975)
[M::mem_pestat] mean and std.dev: (341.50, 169.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1233)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (622, 1091, 1176)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2284)
[M::mem_pestat] mean and std.dev: (858.38, 551.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3064)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 494, 1000)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2558)
[M::mem_pestat] mean and std.dev: (502.14, 399.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3337)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683070 reads in 189.813 CPU sec, 6.178 real sec
[M::process] read 682700 sequences (100000268 bp) in 2.269 CPU sec, 2.342 real sec...
[M::mem_process_seqs] Processed 682962 reads in 123.746 CPU sec, 3.974 real sec
sorting block 82, #reads = 1076836 mem = 536878669 peak = 1054408704
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 282253, 18, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 269, 850)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2136)
[M::mem_pestat] mean and std.dev: (455.85, 437.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2779)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 322, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 987)
[M::mem_pestat] mean and std.dev: (345.23, 171.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1248)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 585, 2427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7015)
[M::mem_pestat] mean and std.dev: (1399.67, 1529.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9309)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 433, 562)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1280)
[M::mem_pestat] mean and std.dev: (328.32, 164.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1639)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 83, #reads = 1076297 mem = 536881735 peak = 1054408704
[M::process] read 682460 sequences (100000028 bp) in 3.012 CPU sec, 3.593 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 282181, 9, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 393, 1384)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3796)
[M::mem_pestat] mean and std.dev: (561.54, 563.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5002)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 320, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 982)
[M::mem_pestat] mean and std.dev: (343.18, 170.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1242)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 252, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 881)
[M::mem_pestat] mean and std.dev: (272.00, 109.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1106)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682318 reads in 196.857 CPU sec, 6.454 real sec
[M::mem_process_seqs] Processed 682700 reads in 127.877 CPU sec, 4.198 real sec
[M::process] read 684440 sequences (100000225 bp) in 2.166 CPU sec, 2.318 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 282915, 4, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 244, 558)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1372)
[M::mem_pestat] mean and std.dev: (315.32, 242.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1779)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 322, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 981)
[M::mem_pestat] mean and std.dev: (344.15, 169.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1240)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 370, 427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 907)
[M::mem_pestat] mean and std.dev: (325.67, 151.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1147)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 84, #reads = 1072925 mem = 536878914 peak = 1054408704
[M::process] read 681852 sequences (100000160 bp) in 2.746 CPU sec, 3.203 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 283940, 12, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 292, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1011)
[M::mem_pestat] mean and std.dev: (311.96, 165.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1281)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 300, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 926)
[M::mem_pestat] mean and std.dev: (327.33, 164.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1170)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 483, 1197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3239)
[M::mem_pestat] mean and std.dev: (507.10, 466.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4260)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 354, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 978)
[M::mem_pestat] mean and std.dev: (330.47, 177.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1234)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682460 reads in 191.330 CPU sec, 6.270 real sec
[M::mem_process_seqs] Processed 684440 reads in 124.668 CPU sec, 4.055 real sec
[M::process] read 681918 sequences (100000092 bp) in 2.180 CPU sec, 2.300 real sec...
sorting block 85, #reads = 1075604 mem = 536877436 peak = 1054408704
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 282532, 15, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 303, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1066)
[M::mem_pestat] mean and std.dev: (365.62, 227.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1363)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 323, 464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 980)
[M::mem_pestat] mean and std.dev: (345.20, 169.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1238)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (59, 316, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 830)
[M::mem_pestat] mean and std.dev: (248.13, 194.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1087)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 368, 500)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1046)
[M::mem_pestat] mean and std.dev: (352.45, 162.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1319)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682370 sequences (100000106 bp) in 2.937 CPU sec, 3.391 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 282655, 7, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 504, 773)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1857)
[M::mem_pestat] mean and std.dev: (463.67, 351.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2399)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 326, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 989)
[M::mem_pestat] mean and std.dev: (347.38, 171.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1250)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 329, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 631)
[M::mem_pestat] mean and std.dev: (277.05, 91.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 771)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681852 reads in 194.643 CPU sec, 6.383 real sec
[M::mem_process_seqs] Processed 681918 reads in 125.409 CPU sec, 4.099 real sec
[M::process] read 681174 sequences (100000126 bp) in 2.476 CPU sec, 2.702 real sec...
sorting block 86, #reads = 1076060 mem = 536878763 peak = 1054408704
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 282408, 15, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 352, 555)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1289)
[M::mem_pestat] mean and std.dev: (379.20, 259.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1656)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 322, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 978)
[M::mem_pestat] mean and std.dev: (343.40, 168.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1236)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1532, 1532, 2303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3845)
[M::mem_pestat] mean and std.dev: (1481.33, 668.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4616)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 377, 1000)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2562)
[M::mem_pestat] mean and std.dev: (510.70, 407.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3343)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680984 sequences (100000109 bp) in 2.461 CPU sec, 2.811 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 282876, 4, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 341, 607)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1391)
[M::mem_pestat] mean and std.dev: (393.35, 271.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1783)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 330, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 981)
[M::mem_pestat] mean and std.dev: (348.92, 168.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1238)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 295, 516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1110)
[M::mem_pestat] mean and std.dev: (346.34, 180.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1407)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682370 reads in 195.958 CPU sec, 6.437 real sec
sorting block 87, #reads = 1074695 mem = 536878667 peak = 1054408704
[M::mem_process_seqs] Processed 681174 reads in 127.426 CPU sec, 4.139 real sec
[M::process] read 680580 sequences (100000031 bp) in 2.489 CPU sec, 2.638 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 282788, 8, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (269, 341, 813)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1901)
[M::mem_pestat] mean and std.dev: (507.10, 407.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2445)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 328, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 961)
[M::mem_pestat] mean and std.dev: (346.45, 166.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1211)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 330, 515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1193)
[M::mem_pestat] mean and std.dev: (428.35, 312.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1677)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 88, #reads = 1073484 mem = 536876509 peak = 1061134336
[M::process] read 680646 sequences (100000215 bp) in 2.706 CPU sec, 3.229 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281600, 4, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 333, 558)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1328)
[M::mem_pestat] mean and std.dev: (422.65, 364.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1880)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 332, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 975)
[M::mem_pestat] mean and std.dev: (350.24, 167.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1229)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 387, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 915)
[M::mem_pestat] mean and std.dev: (356.40, 170.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1151)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680984 reads in 196.743 CPU sec, 6.474 real sec
[M::mem_process_seqs] Processed 680580 reads in 130.501 CPU sec, 4.235 real sec
[M::process] read 680068 sequences (100000021 bp) in 2.379 CPU sec, 2.496 real sec...
sorting block 89, #reads = 1072751 mem = 536881867 peak = 1061134336
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 281832, 9, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 291, 512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1210)
[M::mem_pestat] mean and std.dev: (330.20, 220.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1559)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 331, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 965)
[M::mem_pestat] mean and std.dev: (348.32, 166.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1216)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 356, 796)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1908)
[M::mem_pestat] mean and std.dev: (512.57, 421.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2464)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680196 sequences (100000185 bp) in 2.531 CPU sec, 2.911 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 281600, 7, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 318, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 891)
[M::mem_pestat] mean and std.dev: (273.57, 92.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1113)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 334, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 974)
[M::mem_pestat] mean and std.dev: (351.89, 168.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1227)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 300, 473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1087)
[M::mem_pestat] mean and std.dev: (282.39, 174.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1394)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680646 reads in 200.474 CPU sec, 6.526 real sec
[M::process] read 680184 sequences (100000088 bp) in 1.968 CPU sec, 2.045 real sec...
[M::mem_process_seqs] Processed 680068 reads in 131.174 CPU sec, 4.248 real sec
sorting block 90, #reads = 1070868 mem = 536882221 peak = 1061134336
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 281510, 17, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 322, 485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 977)
[M::mem_pestat] mean and std.dev: (348.12, 213.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1223)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 333, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 968)
[M::mem_pestat] mean and std.dev: (351.57, 168.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1219)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (422, 468, 2229)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5843)
[M::mem_pestat] mean and std.dev: (989.06, 905.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7650)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 327, 464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 944)
[M::mem_pestat] mean and std.dev: (331.69, 168.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1184)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680244 sequences (100000041 bp) in 2.758 CPU sec, 3.255 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 281522, 3, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 277, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 983)
[M::mem_pestat] mean and std.dev: (315.36, 176.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1245)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 332, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 967)
[M::mem_pestat] mean and std.dev: (350.13, 167.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1218)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 341, 491)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1115)
[M::mem_pestat] mean and std.dev: (345.19, 194.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1427)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680196 reads in 201.446 CPU sec, 6.543 real sec
[M::process] read 680098 sequences (100000077 bp) in 2.092 CPU sec, 2.164 real sec...
sorting block 91, #reads = 1073132 mem = 536879211 peak = 1061134336
[M::mem_process_seqs] Processed 680184 reads in 134.630 CPU sec, 4.328 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281926, 14, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 285, 415)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 897)
[M::mem_pestat] mean and std.dev: (257.06, 110.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1138)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 332, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 970)
[M::mem_pestat] mean and std.dev: (350.69, 167.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1222)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1245, 1432, 1432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (871, 1806)
[M::mem_pestat] mean and std.dev: (1408.62, 61.84)
[M::mem_pestat] low and high boundaries for proper pairs: (684, 1993)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 297, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 934)
[M::mem_pestat] mean and std.dev: (330.55, 187.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1181)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680516 sequences (100000008 bp) in 2.602 CPU sec, 3.230 real sec...
sorting block 92, #reads = 1069671 mem = 536885757 peak = 1061134336
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 281770, 22, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 308, 506)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1150)
[M::mem_pestat] mean and std.dev: (411.25, 314.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1668)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 332, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 976)
[M::mem_pestat] mean and std.dev: (351.66, 169.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1230)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (894, 2056, 7290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 20082)
[M::mem_pestat] mean and std.dev: (3130.82, 2853.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 26478)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 364, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 856)
[M::mem_pestat] mean and std.dev: (362.05, 157.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1056)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680244 reads in 200.252 CPU sec, 6.586 real sec
[M::process] read 686212 sequences (100000243 bp) in 2.293 CPU sec, 2.321 real sec...
[M::mem_process_seqs] Processed 680098 reads in 132.386 CPU sec, 4.276 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 281780, 18, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 321, 701)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1573)
[M::mem_pestat] mean and std.dev: (333.08, 181.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2009)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 332, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 983)
[M::mem_pestat] mean and std.dev: (351.52, 170.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1240)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 719, 1021)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2663)
[M::mem_pestat] mean and std.dev: (630.44, 467.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3484)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 312, 556)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1224)
[M::mem_pestat] mean and std.dev: (303.62, 160.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1558)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 93, #reads = 1072129 mem = 536878799 peak = 1061134336
[M::process] read 688852 sequences (100000018 bp) in 3.386 CPU sec, 3.840 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283513, 4, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 276, 533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1129)
[M::mem_pestat] mean and std.dev: (300.81, 156.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1427)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 294, 429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 909)
[M::mem_pestat] mean and std.dev: (319.99, 161.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1149)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 277, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 564)
[M::mem_pestat] mean and std.dev: (257.43, 76.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 680)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680516 reads in 208.529 CPU sec, 6.787 real sec
[M::process] read 689260 sequences (100000072 bp) in 2.031 CPU sec, 2.045 real sec...
[M::mem_process_seqs] Processed 686212 reads in 141.975 CPU sec, 4.602 real sec
sorting block 94, #reads = 1071153 mem = 536880526 peak = 1061134336
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 285190, 4, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 248, 391)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 873)
[M::mem_pestat] mean and std.dev: (277.23, 155.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1114)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 278, 407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 859)
[M::mem_pestat] mean and std.dev: (305.15, 153.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1085)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 315, 505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1149)
[M::mem_pestat] mean and std.dev: (274.29, 155.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1471)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 687618 sequences (100000179 bp) in 2.795 CPU sec, 3.173 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 285615, 5, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 318, 561)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1333)
[M::mem_pestat] mean and std.dev: (333.42, 215.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1719)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 275, 402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 848)
[M::mem_pestat] mean and std.dev: (301.16, 149.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1071)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 333, 622)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1442)
[M::mem_pestat] mean and std.dev: (447.48, 319.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1852)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 686542 sequences (100000145 bp) in 2.127 CPU sec, 2.253 real sec...
[M::mem_process_seqs] Processed 688852 reads in 217.200 CPU sec, 7.061 real sec
[M::mem_process_seqs] Processed 689260 reads in 142.332 CPU sec, 4.583 real sec
sorting block 95, #reads = 1071545 mem = 536877558 peak = 1061134336
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 284949, 7, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 356, 992)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2612)
[M::mem_pestat] mean and std.dev: (535.32, 481.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3422)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 285, 414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 872)
[M::mem_pestat] mean and std.dev: (309.54, 153.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1101)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 341, 517)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1079)
[M::mem_pestat] mean and std.dev: (348.12, 181.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1360)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 685794 sequences (100000089 bp) in 3.194 CPU sec, 3.583 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 284437, 10, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 234, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1105)
[M::mem_pestat] mean and std.dev: (292.53, 223.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1424)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 292, 424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 896)
[M::mem_pestat] mean and std.dev: (316.00, 156.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1132)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (92, 521, 735)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2021)
[M::mem_pestat] mean and std.dev: (526.50, 469.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2664)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 269, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1038)
[M::mem_pestat] mean and std.dev: (307.05, 177.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1329)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 684398 sequences (100000229 bp) in 2.213 CPU sec, 2.237 real sec...
[M::mem_process_seqs] Processed 687618 reads in 214.165 CPU sec, 6.934 real sec
sorting block 96, #reads = 1071019 mem = 536887889 peak = 1061134336
[M::mem_process_seqs] Processed 686542 reads in 137.117 CPU sec, 4.415 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 284583, 4, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 244, 381)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 803)
[M::mem_pestat] mean and std.dev: (275.24, 153.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1014)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 296, 429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 907)
[M::mem_pestat] mean and std.dev: (319.98, 158.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1146)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 245, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 724)
[M::mem_pestat] mean and std.dev: (260.22, 107.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 906)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 97, #reads = 1071261 mem = 536877967 peak = 1071243264
[M::process] read 684086 sequences (100000232 bp) in 2.959 CPU sec, 3.444 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 284053, 7, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 300, 1041)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2715)
[M::mem_pestat] mean and std.dev: (484.70, 544.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3552)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 305, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 927)
[M::mem_pestat] mean and std.dev: (327.42, 161.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1171)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 367, 634)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1440)
[M::mem_pestat] mean and std.dev: (430.65, 267.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1843)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 685794 reads in 213.346 CPU sec, 6.947 real sec
[M::process] read 683862 sequences (100000002 bp) in 2.431 CPU sec, 2.476 real sec...
[M::mem_process_seqs] Processed 684398 reads in 138.027 CPU sec, 4.464 real sec
sorting block 98, #reads = 1071217 mem = 536879079 peak = 1071243264
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 283923, 9, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 307, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1045)
[M::mem_pestat] mean and std.dev: (319.22, 166.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1335)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 309, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 941)
[M::mem_pestat] mean and std.dev: (330.93, 162.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1189)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 240, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1021)
[M::mem_pestat] mean and std.dev: (361.48, 241.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1329)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683580 sequences (100000248 bp) in 3.309 CPU sec, 3.633 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 283891, 11, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 309, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 943)
[M::mem_pestat] mean and std.dev: (334.25, 155.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1183)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 311, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 945)
[M::mem_pestat] mean and std.dev: (333.14, 163.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1194)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (457, 1200, 1270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2896)
[M::mem_pestat] mean and std.dev: (875.60, 566.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3709)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 302, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 940)
[M::mem_pestat] mean and std.dev: (311.76, 157.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1191)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684086 reads in 200.623 CPU sec, 6.568 real sec
[M::process] read 683574 sequences (100000298 bp) in 2.220 CPU sec, 2.375 real sec...
[M::mem_process_seqs] Processed 683862 reads in 131.459 CPU sec, 4.315 real sec
sorting block 99, #reads = 1072498 mem = 536881353 peak = 1071243264
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 283554, 8, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 348, 991)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2529)
[M::mem_pestat] mean and std.dev: (646.79, 591.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3298)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 311, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 948)
[M::mem_pestat] mean and std.dev: (333.10, 163.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1198)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 254, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 634)
[M::mem_pestat] mean and std.dev: (278.30, 115.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 779)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683232 sequences (100000294 bp) in 2.811 CPU sec, 3.239 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 282868, 1, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 261, 382)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (251.97, 94.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 934)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 314, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 952)
[M::mem_pestat] mean and std.dev: (334.27, 163.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1203)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (300, 367, 499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 897)
[M::mem_pestat] mean and std.dev: (330.17, 102.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1096)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683266 sequences (100000206 bp) in 1.986 CPU sec, 2.019 real sec...
[M::mem_process_seqs] Processed 683580 reads in 213.280 CPU sec, 6.903 real sec
sorting block 100, #reads = 1073077 mem = 536884811 peak = 1071243264
[M::mem_process_seqs] Processed 683574 reads in 136.614 CPU sec, 4.370 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 283293, 8, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 280, 481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 967)
[M::mem_pestat] mean and std.dev: (333.09, 171.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1210)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 315, 451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 951)
[M::mem_pestat] mean and std.dev: (335.38, 163.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1201)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 329, 1171)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3069)
[M::mem_pestat] mean and std.dev: (691.12, 684.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4018)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 101, #reads = 1069774 mem = 536877073 peak = 1071243264
[M::process] read 682838 sequences (100000069 bp) in 3.240 CPU sec, 3.693 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 282835, 9, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 205, 267)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 527)
[M::mem_pestat] mean and std.dev: (213.92, 81.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 657)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 314, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 947)
[M::mem_pestat] mean and std.dev: (334.58, 163.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1196)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 321, 713)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1657)
[M::mem_pestat] mean and std.dev: (396.88, 222.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2129)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682268 sequences (100000268 bp) in 2.042 CPU sec, 2.065 real sec...
[M::mem_process_seqs] Processed 683232 reads in 201.216 CPU sec, 6.546 real sec
[M::mem_process_seqs] Processed 683266 reads in 129.060 CPU sec, 4.180 real sec
sorting block 102, #reads = 1071204 mem = 536880416 peak = 1071243264
[M::process] read 682608 sequences (100000034 bp) in 2.881 CPU sec, 3.148 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 282889, 5, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 273, 478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1076)
[M::mem_pestat] mean and std.dev: (293.45, 177.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1375)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 320, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 960)
[M::mem_pestat] mean and std.dev: (340.12, 165.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1212)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 328, 525)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1165)
[M::mem_pestat] mean and std.dev: (335.15, 160.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1485)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682322 sequences (100000200 bp) in 2.045 CPU sec, 2.054 real sec...
[M::mem_process_seqs] Processed 682268 reads in 117.481 CPU sec, 3.763 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 283282, 12, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 387, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 950)
[M::mem_pestat] mean and std.dev: (323.00, 129.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1190)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 316, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 952)
[M::mem_pestat] mean and std.dev: (337.03, 163.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1202)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (56, 2584, 7287)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 21749)
[M::mem_pestat] mean and std.dev: (3244.75, 3150.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 28980)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 333, 644)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1492)
[M::mem_pestat] mean and std.dev: (392.77, 222.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1916)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 282824, 10, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (259, 383, 651)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1435)
[M::mem_pestat] mean and std.dev: (431.88, 244.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1827)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 318, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 962)
[M::mem_pestat] mean and std.dev: (339.75, 166.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1215)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (337, 337, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (67, 742)
[M::mem_pestat] mean and std.dev: (305.25, 143.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 881)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 291, 480)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1034)
[M::mem_pestat] mean and std.dev: (305.67, 168.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1311)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682838 reads in 311.746 CPU sec, 10.062 real sec
sorting block 103, #reads = 1072629 mem = 536879793 peak = 1071243264
[M::mem_process_seqs] Processed 682608 reads in 150.133 CPU sec, 4.881 real sec
[M::process] read 681346 sequences (100000123 bp) in 2.586 CPU sec, 2.703 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 283163, 7, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 289, 575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1313)
[M::mem_pestat] mean and std.dev: (343.87, 234.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1682)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 320, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 966)
[M::mem_pestat] mean and std.dev: (340.93, 166.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1220)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 338, 534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1206)
[M::mem_pestat] mean and std.dev: (390.65, 243.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1542)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 104, #reads = 1072847 mem = 536877647 peak = 1071243264
[M::process] read 681006 sequences (100000262 bp) in 3.041 CPU sec, 3.419 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 282352, 13, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (259, 383, 754)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1744)
[M::mem_pestat] mean and std.dev: (456.24, 353.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2239)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 328, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 979)
[M::mem_pestat] mean and std.dev: (346.95, 168.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1236)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (683, 683, 2133)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5033)
[M::mem_pestat] mean and std.dev: (957.38, 722.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6483)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (306, 464, 515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 933)
[M::mem_pestat] mean and std.dev: (350.84, 135.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1142)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682322 reads in 199.963 CPU sec, 6.522 real sec
[M::process] read 680490 sequences (100000111 bp) in 2.199 CPU sec, 2.300 real sec...
[M::mem_process_seqs] Processed 681346 reads in 130.393 CPU sec, 4.226 real sec
sorting block 105, #reads = 1072188 mem = 536879089 peak = 1071243264
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 281883, 12, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 402, 556)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1230)
[M::mem_pestat] mean and std.dev: (401.34, 260.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1567)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 332, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 991)
[M::mem_pestat] mean and std.dev: (351.51, 170.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1251)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 1851, 4216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12276)
[M::mem_pestat] mean and std.dev: (2266.17, 2638.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16306)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 291, 507)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1147)
[M::mem_pestat] mean and std.dev: (310.06, 176.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1467)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680480 sequences (100000193 bp) in 3.001 CPU sec, 3.396 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 281934, 20, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 260, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1006)
[M::mem_pestat] mean and std.dev: (278.93, 122.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1285)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 336, 474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 994)
[M::mem_pestat] mean and std.dev: (354.09, 170.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1254)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 827, 1342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3622)
[M::mem_pestat] mean and std.dev: (973.20, 1071.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5260)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 390, 888)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2222)
[M::mem_pestat] mean and std.dev: (504.35, 356.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2889)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681006 reads in 197.285 CPU sec, 6.450 real sec
[M::mem_process_seqs] Processed 680490 reads in 129.659 CPU sec, 4.231 real sec
[M::process] read 680734 sequences (100000108 bp) in 2.270 CPU sec, 2.376 real sec...
sorting block 106, #reads = 1071843 mem = 536878365 peak = 1071243264
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 281806, 10, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 340, 485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 981)
[M::mem_pestat] mean and std.dev: (352.87, 167.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1229)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 334, 473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 995)
[M::mem_pestat] mean and std.dev: (353.44, 171.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1256)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (61, 1535, 1648)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4822)
[M::mem_pestat] mean and std.dev: (1071.44, 719.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6409)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (295, 448, 1297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3301)
[M::mem_pestat] mean and std.dev: (666.60, 539.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4303)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680726 sequences (100000226 bp) in 3.199 CPU sec, 3.566 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 281870, 10, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 306, 569)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1301)
[M::mem_pestat] mean and std.dev: (397.66, 287.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1667)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 333, 476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1004)
[M::mem_pestat] mean and std.dev: (354.83, 174.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1268)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (312, 497, 9504)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 27888)
[M::mem_pestat] mean and std.dev: (3136.50, 4172.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 37080)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 388, 772)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1804)
[M::mem_pestat] mean and std.dev: (425.84, 265.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2320)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680480 reads in 197.823 CPU sec, 6.395 real sec
[M::process] read 680758 sequences (100000153 bp) in 2.144 CPU sec, 2.214 real sec...
[M::mem_process_seqs] Processed 680734 reads in 128.756 CPU sec, 4.143 real sec
sorting block 107, #reads = 1072157 mem = 536877239 peak = 1071243264
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 281960, 14, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 246, 576)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1384)
[M::mem_pestat] mean and std.dev: (309.92, 217.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1788)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 331, 473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 995)
[M::mem_pestat] mean and std.dev: (353.30, 173.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1256)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (130, 1280, 2647)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7681)
[M::mem_pestat] mean and std.dev: (1101.36, 1007.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10198)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 376, 697)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1653)
[M::mem_pestat] mean and std.dev: (464.96, 357.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2131)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 108, #reads = 1071687 mem = 536879931 peak = 1071243264
[M::process] read 681712 sequences (100000110 bp) in 3.430 CPU sec, 3.784 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 281878, 9, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 290, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1036)
[M::mem_pestat] mean and std.dev: (325.27, 187.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1321)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 331, 473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 997)
[M::mem_pestat] mean and std.dev: (353.02, 173.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1259)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 495, 659)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1551)
[M::mem_pestat] mean and std.dev: (469.78, 341.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1997)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680726 reads in 202.332 CPU sec, 6.577 real sec
[M::process] read 681658 sequences (100000189 bp) in 2.033 CPU sec, 2.124 real sec...
[M::mem_process_seqs] Processed 680758 reads in 129.698 CPU sec, 4.203 real sec
sorting block 109, #reads = 1071113 mem = 536880702 peak = 1071243264
[M::process] read 686844 sequences (100000001 bp) in 3.274 CPU sec, 3.685 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 281835, 14, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 351, 590)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1356)
[M::mem_pestat] mean and std.dev: (331.80, 181.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1739)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 324, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 990)
[M::mem_pestat] mean and std.dev: (349.43, 174.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1251)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (102, 375, 2588)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7560)
[M::mem_pestat] mean and std.dev: (1348.50, 1604.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10046)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 315, 512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1078)
[M::mem_pestat] mean and std.dev: (349.14, 165.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1361)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 686806 sequences (100000287 bp) in 2.154 CPU sec, 2.308 real sec...
[M::mem_process_seqs] Processed 681658 reads in 133.016 CPU sec, 4.252 real sec
sorting block 110, #reads = 1066257 mem = 536879664 peak = 1071243264
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 282660, 13, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 308, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 739)
[M::mem_pestat] mean and std.dev: (248.75, 114.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 927)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 321, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 983)
[M::mem_pestat] mean and std.dev: (347.42, 174.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1242)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 373, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 980)
[M::mem_pestat] mean and std.dev: (338.50, 222.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1245)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 305, 705)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1645)
[M::mem_pestat] mean and std.dev: (453.38, 396.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2115)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 284763, 23, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 250, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 729)
[M::mem_pestat] mean and std.dev: (267.26, 143.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 919)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 288, 422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 894)
[M::mem_pestat] mean and std.dev: (315.86, 159.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1130)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (390, 536, 893)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1899)
[M::mem_pestat] mean and std.dev: (536.53, 240.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2402)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 258, 524)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1158)
[M::mem_pestat] mean and std.dev: (311.85, 208.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1475)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681712 reads in 328.046 CPU sec, 10.641 real sec
[M::process] read 685668 sequences (100000175 bp) in 2.225 CPU sec, 2.558 real sec...
[M::mem_process_seqs] Processed 686844 reads in 159.991 CPU sec, 5.246 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 284712, 16, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 386, 595)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1361)
[M::mem_pestat] mean and std.dev: (414.76, 276.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1744)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 290, 424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 898)
[M::mem_pestat] mean and std.dev: (316.83, 159.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1135)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 2062, 2639)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7599)
[M::mem_pestat] mean and std.dev: (1584.80, 1277.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10079)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 300, 529)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1151)
[M::mem_pestat] mean and std.dev: (369.00, 203.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1462)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 111, #reads = 1070115 mem = 536877067 peak = 1071243264
[M::process] read 684486 sequences (100000142 bp) in 3.314 CPU sec, 3.656 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 284110, 12, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 339, 510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1110)
[M::mem_pestat] mean and std.dev: (359.26, 228.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1410)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 297, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 911)
[M::mem_pestat] mean and std.dev: (322.60, 162.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1151)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (589, 1485, 3882)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10468)
[M::mem_pestat] mean and std.dev: (1645.42, 1407.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13761)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 363, 584)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1418)
[M::mem_pestat] mean and std.dev: (382.25, 230.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1835)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 686806 reads in 195.111 CPU sec, 6.436 real sec
[M::mem_process_seqs] Processed 685668 reads in 124.087 CPU sec, 4.158 real sec
[M::process] read 684028 sequences (100000202 bp) in 2.522 CPU sec, 2.978 real sec...
sorting block 112, #reads = 1078027 mem = 536879830 peak = 1071243264
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 283201, 10, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 343, 752)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1808)
[M::mem_pestat] mean and std.dev: (485.84, 408.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2336)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 304, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 927)
[M::mem_pestat] mean and std.dev: (328.21, 162.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1171)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (77, 608, 690)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1916)
[M::mem_pestat] mean and std.dev: (347.00, 295.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2529)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 362, 673)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1625)
[M::mem_pestat] mean and std.dev: (326.70, 190.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2101)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683904 sequences (100000263 bp) in 2.788 CPU sec, 3.163 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 283320, 21, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 315, 537)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1199)
[M::mem_pestat] mean and std.dev: (344.48, 236.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1530)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 310, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 936)
[M::mem_pestat] mean and std.dev: (332.57, 164.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1182)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (783, 783, 1815)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3879)
[M::mem_pestat] mean and std.dev: (1100.05, 575.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4911)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 501, 1236)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3244)
[M::mem_pestat] mean and std.dev: (651.00, 517.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4248)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684486 reads in 194.282 CPU sec, 6.385 real sec
[M::mem_process_seqs] Processed 684028 reads in 120.798 CPU sec, 3.956 real sec
[M::process] read 683526 sequences (100000281 bp) in 2.527 CPU sec, 2.706 real sec...
sorting block 113, #reads = 1077457 mem = 536879690 peak = 1071243264
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 283805, 7, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 200, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1019)
[M::mem_pestat] mean and std.dev: (245.53, 150.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1304)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 310, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 945)
[M::mem_pestat] mean and std.dev: (333.60, 165.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1194)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 329, 415)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 807)
[M::mem_pestat] mean and std.dev: (322.44, 140.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1003)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683076 sequences (100000276 bp) in 3.049 CPU sec, 3.348 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 283394, 15, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 368, 541)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1179)
[M::mem_pestat] mean and std.dev: (351.35, 194.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1498)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 313, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 949)
[M::mem_pestat] mean and std.dev: (335.35, 165.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1199)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (112, 577, 1168)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3280)
[M::mem_pestat] mean and std.dev: (817.47, 777.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4336)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 288, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 720)
[M::mem_pestat] mean and std.dev: (267.05, 116.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 893)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683904 reads in 192.642 CPU sec, 6.328 real sec
[M::mem_process_seqs] Processed 683526 reads in 121.810 CPU sec, 4.012 real sec
sorting block 114, #reads = 1076807 mem = 536879633 peak = 1071243264
[M::process] read 682464 sequences (100000188 bp) in 2.583 CPU sec, 2.942 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 283309, 10, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 211, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1016)
[M::mem_pestat] mean and std.dev: (308.97, 189.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1296)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 317, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 960)
[M::mem_pestat] mean and std.dev: (338.45, 166.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1213)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (784, 1017, 2295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5317)
[M::mem_pestat] mean and std.dev: (1287.70, 717.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6828)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 289, 414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 840)
[M::mem_pestat] mean and std.dev: (298.68, 131.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1053)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 115, #reads = 1077425 mem = 536880939 peak = 1071243264
[M::process] read 682366 sequences (100000298 bp) in 3.216 CPU sec, 3.591 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 283535, 10, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 248, 577)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1339)
[M::mem_pestat] mean and std.dev: (352.33, 249.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1720)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 320, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 963)
[M::mem_pestat] mean and std.dev: (341.18, 167.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1216)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (119, 437, 1004)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2774)
[M::mem_pestat] mean and std.dev: (551.70, 409.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3659)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 314, 587)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1311)
[M::mem_pestat] mean and std.dev: (385.59, 196.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1673)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683076 reads in 192.527 CPU sec, 6.312 real sec
[M::mem_process_seqs] Processed 682464 reads in 125.301 CPU sec, 4.168 real sec
[M::process] read 682176 sequences (100000198 bp) in 2.095 CPU sec, 2.361 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 282773, 4, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 400, 637)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1495)
[M::mem_pestat] mean and std.dev: (399.32, 241.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1924)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 321, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 957)
[M::mem_pestat] mean and std.dev: (340.92, 166.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1208)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 329, 569)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1347)
[M::mem_pestat] mean and std.dev: (344.41, 185.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1736)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 116, #reads = 1076167 mem = 536880981 peak = 1071243264
[M::process] read 682436 sequences (100000163 bp) in 2.882 CPU sec, 3.328 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 282564, 10, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 216, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1104)
[M::mem_pestat] mean and std.dev: (271.17, 170.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1427)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 323, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 967)
[M::mem_pestat] mean and std.dev: (343.03, 167.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1221)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (889, 1466, 1629)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3109)
[M::mem_pestat] mean and std.dev: (1330.30, 551.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3849)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 324, 419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 783)
[M::mem_pestat] mean and std.dev: (311.34, 121.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 965)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682366 reads in 190.508 CPU sec, 6.307 real sec
[M::mem_process_seqs] Processed 682176 reads in 127.835 CPU sec, 4.195 real sec
[M::process] read 682096 sequences (100000069 bp) in 2.733 CPU sec, 2.969 real sec...
sorting block 117, #reads = 1075258 mem = 536878827 peak = 1071243264
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 282987, 4, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (266, 271, 874)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2090)
[M::mem_pestat] mean and std.dev: (422.75, 425.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2698)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 322, 460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 972)
[M::mem_pestat] mean and std.dev: (342.96, 168.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1228)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 259, 404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 778)
[M::mem_pestat] mean and std.dev: (309.47, 156.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 965)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681896 sequences (100000100 bp) in 2.830 CPU sec, 3.187 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 283280, 12, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 438, 550)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1166)
[M::mem_pestat] mean and std.dev: (416.16, 190.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1474)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 324, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 971)
[M::mem_pestat] mean and std.dev: (344.46, 168.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1226)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (102, 1109, 1109)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3123)
[M::mem_pestat] mean and std.dev: (878.08, 784.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4130)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 345, 375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 677)
[M::mem_pestat] mean and std.dev: (287.38, 85.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 828)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682436 reads in 194.262 CPU sec, 6.303 real sec
[M::mem_process_seqs] Processed 682096 reads in 129.114 CPU sec, 4.132 real sec
sorting block 118, #reads = 1074946 mem = 536880992 peak = 1071243264
[M::process] read 681606 sequences (100000163 bp) in 2.329 CPU sec, 2.440 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 282398, 6, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 213, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1090)
[M::mem_pestat] mean and std.dev: (271.02, 162.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1402)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 325, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 977)
[M::mem_pestat] mean and std.dev: (345.57, 169.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1234)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 351, 477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 969)
[M::mem_pestat] mean and std.dev: (345.72, 165.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1215)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681630 sequences (100000297 bp) in 2.957 CPU sec, 3.359 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 283220, 11, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 299, 545)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1177)
[M::mem_pestat] mean and std.dev: (410.72, 299.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1609)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 327, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 982)
[M::mem_pestat] mean and std.dev: (347.72, 170.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1240)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (871, 932, 1710)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3388)
[M::mem_pestat] mean and std.dev: (1321.91, 829.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4639)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 491)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1165)
[M::mem_pestat] mean and std.dev: (260.33, 170.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1502)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681896 reads in 189.917 CPU sec, 6.180 real sec
sorting block 119, #reads = 1074599 mem = 536880508 peak = 1071243264
[M::mem_process_seqs] Processed 681606 reads in 126.112 CPU sec, 4.071 real sec
[M::process] read 681758 sequences (100000152 bp) in 2.545 CPU sec, 2.763 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 281578, 12, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 232, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1016)
[M::mem_pestat] mean and std.dev: (273.02, 180.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1303)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 326, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 981)
[M::mem_pestat] mean and std.dev: (346.83, 169.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1239)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 320, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 596)
[M::mem_pestat] mean and std.dev: (227.70, 121.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 734)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (270, 328, 511)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 993)
[M::mem_pestat] mean and std.dev: (339.00, 131.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1234)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 120, #reads = 1073811 mem = 536879552 peak = 1098264576
[M::process] read 681496 sequences (100000065 bp) in 3.034 CPU sec, 3.315 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 282332, 11, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (309, 448, 960)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2262)
[M::mem_pestat] mean and std.dev: (457.38, 297.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2913)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 327, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 979)
[M::mem_pestat] mean and std.dev: (346.92, 169.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1236)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (870, 2375, 2478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5694)
[M::mem_pestat] mean and std.dev: (1630.73, 927.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7302)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 350, 477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 927)
[M::mem_pestat] mean and std.dev: (341.22, 157.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1152)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681630 reads in 200.939 CPU sec, 6.512 real sec
[M::process] read 681316 sequences (100000234 bp) in 1.843 CPU sec, 1.857 real sec...
[M::mem_process_seqs] Processed 681758 reads in 127.212 CPU sec, 4.113 real sec
sorting block 121, #reads = 1072364 mem = 536880742 peak = 1098264576
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 281974, 14, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 270, 1015)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2715)
[M::mem_pestat] mean and std.dev: (512.43, 481.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3565)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 326, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 970)
[M::mem_pestat] mean and std.dev: (345.56, 167.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1224)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (266, 451, 723)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1637)
[M::mem_pestat] mean and std.dev: (400.17, 257.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2094)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 255, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 970)
[M::mem_pestat] mean and std.dev: (345.26, 209.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1231)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681310 sequences (100000179 bp) in 2.948 CPU sec, 3.292 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 282297, 12, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 246, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 663)
[M::mem_pestat] mean and std.dev: (225.81, 81.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 820)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 326, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 959)
[M::mem_pestat] mean and std.dev: (344.99, 166.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1209)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (545, 797, 2327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5891)
[M::mem_pestat] mean and std.dev: (1075.08, 831.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7673)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 319, 501)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1191)
[M::mem_pestat] mean and std.dev: (340.33, 237.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1536)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681496 reads in 204.906 CPU sec, 6.606 real sec
[M::process] read 681442 sequences (100000220 bp) in 2.314 CPU sec, 2.375 real sec...
[M::mem_process_seqs] Processed 681316 reads in 129.322 CPU sec, 4.140 real sec
sorting block 122, #reads = 1072710 mem = 536877617 peak = 1098264576
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 282408, 9, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 255, 412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (255.91, 93.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 916)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 326, 460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 962)
[M::mem_pestat] mean and std.dev: (345.18, 166.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1213)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (273, 424, 914)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2196)
[M::mem_pestat] mean and std.dev: (522.22, 491.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2837)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681514 sequences (100000056 bp) in 3.103 CPU sec, 3.433 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 282277, 21, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 423, 719)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1807)
[M::mem_pestat] mean and std.dev: (486.37, 375.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2351)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 324, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 961)
[M::mem_pestat] mean and std.dev: (343.86, 166.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1212)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (91, 966, 5120)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 15178)
[M::mem_pestat] mean and std.dev: (2459.48, 2774.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 20207)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 329, 553)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1235)
[M::mem_pestat] mean and std.dev: (345.97, 181.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1576)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681466 sequences (100000268 bp) in 1.893 CPU sec, 1.921 real sec...
[M::mem_process_seqs] Processed 681310 reads in 201.285 CPU sec, 6.524 real sec
sorting block 123, #reads = 1071712 mem = 536879223 peak = 1098264576
[M::mem_process_seqs] Processed 681442 reads in 131.382 CPU sec, 4.216 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 282586, 24, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 241, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 670)
[M::mem_pestat] mean and std.dev: (232.71, 95.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 841)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 322, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 957)
[M::mem_pestat] mean and std.dev: (342.38, 165.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1207)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (267, 546, 2745)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7701)
[M::mem_pestat] mean and std.dev: (768.16, 810.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10179)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 250, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 993)
[M::mem_pestat] mean and std.dev: (337.27, 216.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1261)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 124, #reads = 1071462 mem = 536878119 peak = 1098264576
[M::process] read 681750 sequences (100000279 bp) in 3.255 CPU sec, 3.695 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 282617, 3, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 377, 702)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1734)
[M::mem_pestat] mean and std.dev: (435.92, 311.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2250)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 322, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 965)
[M::mem_pestat] mean and std.dev: (342.94, 166.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1218)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 298, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 861)
[M::mem_pestat] mean and std.dev: (320.15, 129.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1076)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681514 reads in 203.952 CPU sec, 6.595 real sec
[M::process] read 681682 sequences (100000270 bp) in 2.149 CPU sec, 2.175 real sec...
[M::mem_process_seqs] Processed 681466 reads in 133.448 CPU sec, 4.309 real sec
sorting block 125, #reads = 1071771 mem = 536878730 peak = 1098264576
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 282620, 10, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 376, 550)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1244)
[M::mem_pestat] mean and std.dev: (387.39, 213.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1591)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 322, 460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 968)
[M::mem_pestat] mean and std.dev: (343.77, 167.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1222)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (938, 2423, 4810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12554)
[M::mem_pestat] mean and std.dev: (2353.50, 1754.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16426)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 308, 478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1008)
[M::mem_pestat] mean and std.dev: (363.62, 224.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1273)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681432 sequences (100000021 bp) in 3.224 CPU sec, 3.547 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 282706, 10, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 279, 1672)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4606)
[M::mem_pestat] mean and std.dev: (776.40, 1098.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6073)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 322, 460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 968)
[M::mem_pestat] mean and std.dev: (344.17, 169.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1222)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (246, 762, 3670)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10518)
[M::mem_pestat] mean and std.dev: (1498.70, 1477.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13942)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 331, 526)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1076)
[M::mem_pestat] mean and std.dev: (327.36, 150.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1351)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681750 reads in 201.818 CPU sec, 6.479 real sec
[M::process] read 682076 sequences (100000160 bp) in 2.034 CPU sec, 2.074 real sec...
[M::mem_process_seqs] Processed 681682 reads in 133.615 CPU sec, 4.272 real sec
sorting block 126, #reads = 1071849 mem = 536878179 peak = 1098264576
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 282454, 8, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 353, 633)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1519)
[M::mem_pestat] mean and std.dev: (343.80, 267.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1962)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 322, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 969)
[M::mem_pestat] mean and std.dev: (345.03, 169.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1223)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (267, 361, 719)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1623)
[M::mem_pestat] mean and std.dev: (386.98, 301.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2075)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683626 sequences (100000110 bp) in 3.092 CPU sec, 3.335 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 282702, 5, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 272, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 918)
[M::mem_pestat] mean and std.dev: (271.00, 122.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1159)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 321, 460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 968)
[M::mem_pestat] mean and std.dev: (344.38, 170.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1222)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (261, 366, 600)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1278)
[M::mem_pestat] mean and std.dev: (382.03, 158.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1617)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 690678 sequences (100000266 bp) in 1.740 CPU sec, 1.739 real sec...
[M::mem_process_seqs] Processed 681432 reads in 186.436 CPU sec, 5.963 real sec
[M::mem_process_seqs] Processed 682076 reads in 116.508 CPU sec, 3.703 real sec
sorting block 127, #reads = 1071182 mem = 536883114 peak = 1098264576
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 282655, 3, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 269, 396)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 776)
[M::mem_pestat] mean and std.dev: (275.47, 111.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 966)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 313, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 967)
[M::mem_pestat] mean and std.dev: (339.06, 171.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1223)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 366, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 872)
[M::mem_pestat] mean and std.dev: (339.98, 134.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1079)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 689832 sequences (100000091 bp) in 3.009 CPU sec, 3.138 real sec...
[M::process] read 688714 sequences (100000161 bp) in 1.600 CPU sec, 1.594 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 285989, 13, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 303, 525)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1279)
[M::mem_pestat] mean and std.dev: (364.43, 268.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1656)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 268, 395)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 835)
[M::mem_pestat] mean and std.dev: (297.11, 151.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1055)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (564, 1788, 2005)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4887)
[M::mem_pestat] mean and std.dev: (1310.00, 732.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6328)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 312, 393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 783)
[M::mem_pestat] mean and std.dev: (311.70, 133.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 978)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683626 reads in 197.827 CPU sec, 6.300 real sec
sorting block 128, #reads = 1069356 mem = 536878632 peak = 1098264576
[M::mem_process_seqs] Processed 690678 reads in 126.055 CPU sec, 4.033 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 285636, 4, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 237, 382)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 834)
[M::mem_pestat] mean and std.dev: (271.88, 135.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1060)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 273, 402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 850)
[M::mem_pestat] mean and std.dev: (301.20, 152.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1074)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 328, 535)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1165)
[M::mem_pestat] mean and std.dev: (405.87, 252.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1480)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 129, #reads = 1064787 mem = 536878703 peak = 1102696448
[M::process] read 687474 sequences (100000041 bp) in 3.028 CPU sec, 3.365 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 285078, 17, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 273, 641)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1613)
[M::mem_pestat] mean and std.dev: (362.83, 263.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2099)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 280, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 865)
[M::mem_pestat] mean and std.dev: (305.78, 153.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1093)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (501, 1058, 2965)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7893)
[M::mem_pestat] mean and std.dev: (1627.53, 1224.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10357)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 297, 473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1007)
[M::mem_pestat] mean and std.dev: (298.28, 140.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1274)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 686364 sequences (100000266 bp) in 2.092 CPU sec, 2.107 real sec...
[M::mem_process_seqs] Processed 689832 reads in 216.723 CPU sec, 7.016 real sec
[M::mem_process_seqs] Processed 688714 reads in 140.435 CPU sec, 4.515 real sec
sorting block 130, #reads = 1070999 mem = 536878163 peak = 1102696448
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 285128, 8, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 259, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (292.12, 192.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1062)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 288, 419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 887)
[M::mem_pestat] mean and std.dev: (312.89, 156.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1121)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 293, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 934)
[M::mem_pestat] mean and std.dev: (278.53, 116.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1175)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 685406 sequences (100000201 bp) in 3.540 CPU sec, 3.824 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 284687, 10, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 244, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1013)
[M::mem_pestat] mean and std.dev: (331.60, 197.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1290)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 294, 425)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 897)
[M::mem_pestat] mean and std.dev: (317.54, 157.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1133)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (20, 485, 832)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2456)
[M::mem_pestat] mean and std.dev: (519.00, 437.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3268)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 224, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 630)
[M::mem_pestat] mean and std.dev: (246.59, 94.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 772)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 684716 sequences (100000263 bp) in 2.118 CPU sec, 2.121 real sec...
[M::mem_process_seqs] Processed 687474 reads in 209.871 CPU sec, 6.719 real sec
[M::mem_process_seqs] Processed 686364 reads in 134.339 CPU sec, 4.285 real sec
sorting block 131, #reads = 1070665 mem = 536880906 peak = 1102696448
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 284017, 9, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 360, 539)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1299)
[M::mem_pestat] mean and std.dev: (296.61, 168.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1679)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 300, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 912)
[M::mem_pestat] mean and std.dev: (322.80, 159.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1152)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 286, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 586)
[M::mem_pestat] mean and std.dev: (276.95, 105.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 709)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 684242 sequences (100000074 bp) in 3.713 CPU sec, 3.999 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 284066, 14, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 258, 555)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1369)
[M::mem_pestat] mean and std.dev: (346.61, 208.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1776)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 306, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 928)
[M::mem_pestat] mean and std.dev: (328.06, 161.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1172)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (591, 1933, 2076)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5046)
[M::mem_pestat] mean and std.dev: (1352.07, 726.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6531)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 263, 404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 854)
[M::mem_pestat] mean and std.dev: (277.25, 159.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1079)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 685406 reads in 205.700 CPU sec, 6.586 real sec
[M::process] read 683904 sequences (100000005 bp) in 2.208 CPU sec, 2.231 real sec...
sorting block 132, #reads = 1072308 mem = 536879857 peak = 1102696448
[M::mem_process_seqs] Processed 684716 reads in 130.224 CPU sec, 4.134 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 283536, 15, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 368, 478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1052)
[M::mem_pestat] mean and std.dev: (356.82, 165.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1339)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 309, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 935)
[M::mem_pestat] mean and std.dev: (330.41, 161.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1181)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1815, 1815, 1983)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1479, 2319)
[M::mem_pestat] mean and std.dev: (1883.25, 69.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1311, 2487)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 250, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 592)
[M::mem_pestat] mean and std.dev: (272.68, 92.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 725)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 133, #reads = 1072568 mem = 536880095 peak = 1102696448
[M::process] read 683504 sequences (100000123 bp) in 3.534 CPU sec, 3.796 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 283455, 13, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 413, 578)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1262)
[M::mem_pestat] mean and std.dev: (440.49, 247.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1604)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 311, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 937)
[M::mem_pestat] mean and std.dev: (332.59, 162.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1183)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (535, 873, 1342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2956)
[M::mem_pestat] mean and std.dev: (648.73, 435.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3763)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (267, 319, 475)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 891)
[M::mem_pestat] mean and std.dev: (338.95, 159.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1099)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684242 reads in 203.391 CPU sec, 6.519 real sec
[M::process] read 683344 sequences (100000092 bp) in 2.142 CPU sec, 2.185 real sec...
[M::mem_process_seqs] Processed 683904 reads in 131.683 CPU sec, 4.178 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283352, 19, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 380, 1227)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3225)
[M::mem_pestat] mean and std.dev: (645.22, 585.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4224)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 316, 451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 951)
[M::mem_pestat] mean and std.dev: (336.36, 164.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1201)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 560, 1950)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5476)
[M::mem_pestat] mean and std.dev: (954.58, 932.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7239)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 271, 384)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 780)
[M::mem_pestat] mean and std.dev: (272.23, 138.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 978)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 134, #reads = 1072482 mem = 536880737 peak = 1102696448
[M::process] read 682972 sequences (100000224 bp) in 3.579 CPU sec, 3.850 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 283295, 11, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 310, 777)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1877)
[M::mem_pestat] mean and std.dev: (530.49, 520.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2614)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 316, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 954)
[M::mem_pestat] mean and std.dev: (337.11, 165.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1205)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (383, 536, 2300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6134)
[M::mem_pestat] mean and std.dev: (1173.73, 950.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8051)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 356, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 878)
[M::mem_pestat] mean and std.dev: (322.22, 145.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1101)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683504 reads in 206.692 CPU sec, 6.619 real sec
[M::process] read 683116 sequences (100000030 bp) in 2.197 CPU sec, 2.217 real sec...
[M::mem_process_seqs] Processed 683344 reads in 134.766 CPU sec, 4.277 real sec
sorting block 135, #reads = 1071441 mem = 536878468 peak = 1102696448
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 283301, 21, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 374, 1018)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2684)
[M::mem_pestat] mean and std.dev: (563.21, 530.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3517)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 316, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 963)
[M::mem_pestat] mean and std.dev: (338.60, 167.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1217)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (353, 665, 2493)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6773)
[M::mem_pestat] mean and std.dev: (1236.71, 1408.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8913)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 356, 664)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1556)
[M::mem_pestat] mean and std.dev: (398.65, 269.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2002)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682560 sequences (100000241 bp) in 3.472 CPU sec, 3.789 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 283194, 4, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 257, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 785)
[M::mem_pestat] mean and std.dev: (246.34, 116.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 993)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 317, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 964)
[M::mem_pestat] mean and std.dev: (339.50, 167.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1218)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 323, 540)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1282)
[M::mem_pestat] mean and std.dev: (334.46, 227.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1653)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682972 reads in 208.221 CPU sec, 6.668 real sec
[M::process] read 682402 sequences (100000132 bp) in 1.929 CPU sec, 1.937 real sec...
[M::mem_process_seqs] Processed 683116 reads in 135.401 CPU sec, 4.305 real sec
sorting block 136, #reads = 1070410 mem = 536881453 peak = 1102696448
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 282581, 8, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 215, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 822)
[M::mem_pestat] mean and std.dev: (223.59, 113.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1050)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 316, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 950)
[M::mem_pestat] mean and std.dev: (337.90, 165.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1199)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (286, 389, 514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 970)
[M::mem_pestat] mean and std.dev: (394.14, 177.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1198)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682520 sequences (100000284 bp) in 3.100 CPU sec, 3.347 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 283194, 7, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 243, 410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 876)
[M::mem_pestat] mean and std.dev: (270.51, 142.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1109)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 318, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 965)
[M::mem_pestat] mean and std.dev: (340.88, 168.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1219)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 301, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (301.29, 131.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 851)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682572 sequences (100000130 bp) in 2.213 CPU sec, 2.216 real sec...
[M::mem_process_seqs] Processed 682560 reads in 202.465 CPU sec, 6.472 real sec
sorting block 137, #reads = 1071428 mem = 536882512 peak = 1102696448
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 283209, 3, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 252, 876)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2252)
[M::mem_pestat] mean and std.dev: (450.14, 481.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2940)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 316, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 961)
[M::mem_pestat] mean and std.dev: (339.86, 167.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1214)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 304, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 903)
[M::mem_pestat] mean and std.dev: (330.47, 182.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1136)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682218 sequences (100000124 bp) in 2.309 CPU sec, 2.347 real sec...
[M::mem_process_seqs] Processed 682520 reads in 114.373 CPU sec, 3.912 real sec
sorting block 138, #reads = 1072145 mem = 536880700 peak = 1106235392
[M::mem_process_seqs] Processed 682402 reads in 288.960 CPU sec, 9.489 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 282429, 4, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (125, 263, 557)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1421)
[M::mem_pestat] mean and std.dev: (324.68, 250.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1853)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 315, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 961)
[M::mem_pestat] mean and std.dev: (338.90, 167.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1214)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 347, 936)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2458)
[M::mem_pestat] mean and std.dev: (550.82, 586.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3219)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682172 sequences (100000005 bp) in 2.905 CPU sec, 3.159 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 283030, 8, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 310, 1154)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3162)
[M::mem_pestat] mean and std.dev: (464.73, 406.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4166)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 321, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 973)
[M::mem_pestat] mean and std.dev: (344.15, 170.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1229)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 291, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 607)
[M::mem_pestat] mean and std.dev: (292.14, 114.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 751)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682572 reads in 208.149 CPU sec, 6.642 real sec
sorting block 139, #reads = 1071898 mem = 536881333 peak = 1106235392
[M::mem_process_seqs] Processed 682218 reads in 111.471 CPU sec, 3.522 real sec
[M::process] read 681650 sequences (100000091 bp) in 1.963 CPU sec, 2.030 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 282113, 11, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (249, 339, 474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 924)
[M::mem_pestat] mean and std.dev: (334.22, 157.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1149)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 321, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 973)
[M::mem_pestat] mean and std.dev: (344.16, 170.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1229)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (407, 548, 719)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1343)
[M::mem_pestat] mean and std.dev: (511.64, 229.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1655)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 322, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1057)
[M::mem_pestat] mean and std.dev: (278.40, 136.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1353)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 140, #reads = 1072672 mem = 536881383 peak = 1106235392
[M::process] read 681910 sequences (100000022 bp) in 2.785 CPU sec, 2.941 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 282588, 6, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 338, 426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 886)
[M::mem_pestat] mean and std.dev: (275.40, 117.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1116)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 321, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 962)
[M::mem_pestat] mean and std.dev: (343.31, 168.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1214)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 402, 722)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1656)
[M::mem_pestat] mean and std.dev: (511.45, 369.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2123)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681534 sequences (100000139 bp) in 1.620 CPU sec, 1.615 real sec...
[M::mem_process_seqs] Processed 682172 reads in 169.044 CPU sec, 5.369 real sec
[M::mem_process_seqs] Processed 681650 reads in 109.590 CPU sec, 3.463 real sec
sorting block 141, #reads = 1073555 mem = 536878088 peak = 1106235392
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 282571, 7, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 451, 975)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2457)
[M::mem_pestat] mean and std.dev: (660.03, 552.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3198)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 322, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 971)
[M::mem_pestat] mean and std.dev: (344.68, 170.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1226)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 319, 533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1175)
[M::mem_pestat] mean and std.dev: (381.16, 259.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1496)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681290 sequences (100000061 bp) in 2.994 CPU sec, 3.128 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 282520, 11, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 405, 543)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1255)
[M::mem_pestat] mean and std.dev: (383.78, 281.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1611)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 324, 464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 978)
[M::mem_pestat] mean and std.dev: (347.04, 171.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1235)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (46, 261, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1027)
[M::mem_pestat] mean and std.dev: (287.45, 253.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1354)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (279, 340, 473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 861)
[M::mem_pestat] mean and std.dev: (305.37, 105.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1055)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681910 reads in 154.570 CPU sec, 4.901 real sec
[M::mem_process_seqs] Processed 681534 reads in 98.471 CPU sec, 3.096 real sec
[M::process] read 681250 sequences (100000204 bp) in 2.220 CPU sec, 2.280 real sec...
sorting block 142, #reads = 1074281 mem = 536880222 peak = 1106235392
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 282304, 4, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 308, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 987)
[M::mem_pestat] mean and std.dev: (335.74, 212.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1250)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 326, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 982)
[M::mem_pestat] mean and std.dev: (348.79, 172.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1240)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 332, 560)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1302)
[M::mem_pestat] mean and std.dev: (394.72, 256.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1673)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681278 sequences (100000255 bp) in 2.718 CPU sec, 2.832 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 282224, 15, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 289, 532)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1214)
[M::mem_pestat] mean and std.dev: (342.51, 212.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1555)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 328, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 984)
[M::mem_pestat] mean and std.dev: (350.53, 173.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1242)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 519, 861)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2191)
[M::mem_pestat] mean and std.dev: (462.64, 368.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2856)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 264, 387)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 745)
[M::mem_pestat] mean and std.dev: (291.12, 126.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 924)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681290 reads in 157.654 CPU sec, 5.016 real sec
[M::process] read 512416 sequences (75093799 bp) in 1.872 CPU sec, 1.914 real sec...
[M::mem_process_seqs] Processed 681250 reads in 107.408 CPU sec, 3.384 real sec
sorting block 143, #reads = 1074702 mem = 536880821 peak = 1106235392
sorting block 144, #reads = 1074384 mem = 536884520 peak = 1106235392
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 282716, 13, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 306, 625)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1549)
[M::mem_pestat] mean and std.dev: (356.06, 269.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2011)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 328, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 995)
[M::mem_pestat] mean and std.dev: (351.83, 175.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1257)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 435, 918)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2468)
[M::mem_pestat] mean and std.dev: (632.38, 614.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3243)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 380, 612)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1376)
[M::mem_pestat] mean and std.dev: (443.00, 267.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1758)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 212689, 5, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 366, 1010)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2590)
[M::mem_pestat] mean and std.dev: (682.41, 704.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3501)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 321, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 973)
[M::mem_pestat] mean and std.dev: (344.25, 171.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1229)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 292, 422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 830)
[M::mem_pestat] mean and std.dev: (302.58, 134.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1034)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681278 reads in 151.580 CPU sec, 4.923 real sec
[M::mem_process_seqs] Processed 512416 reads in 87.942 CPU sec, 2.850 real sec
sorting block 145, #reads = 1072899 mem = 536880600 peak = 1106235392
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 155997548
overall: 69963288576 mem 25530.082 user 740.367 sys 886.009 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1136_3MV-T1-TDNA-1_A23MHWWLT4_1.L003\tPU:L003\tSM:1136_3MV-T1-TDNA-1_A23MHWWLT4_1\tLB:1136_3MV-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1136_3MV-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1136_3MV-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 886.054 sec; CPU: 26270.461 sec
sorting block 146, #reads = 152676 mem = 76702666 peak = 1106235392
uniq header count 1
merging 147 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31 max 192
algo: util-sort
license: sentieon:util=1
output file size: 8771716362
output reads: 157078492
bam_mem_sort: 147 calls 107.303 user 2.374 sys 113.902 real
bam_write: 147 calls 89.329 user 6.859 sys 194.232 real
execute: 1 calls 47.806 user 2.081 sys 943.497 real
merge_files: 1 calls 47.773 user 2.068 sys 57.379 real
parse_chunk: 2339 calls 107.529 user 30.090 sys 184.062 real
read_chunk: 6309 calls 56.537 user 34.211 sys 814.494 real
sort_block: 1 calls 38.311 user 33.446 sys 789.099 real
write_chunk: 3968 calls 47.387 user 1.795 sys 56.395 real
overall: 3361173504 mem 2283.148 user 96.957 sys 943.520 real
ls: cannot access '*.cram': No such file or directory