This software is licensed to bgold@natera.com by Sentieon Inc.
cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1029_HTI-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 1739.362 CPU sec, 64.619 real sec
[M::process] read 702442 sequences (100000238 bp) in 1.125 CPU sec, 1.132 real sec...
[M::process] read 701664 sequences (100000298 bp) in 1.652 CPU sec, 1.699 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 282920, 32, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 516, 1959)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5405)
[M::mem_pestat] mean and std.dev: (1111.77, 1244.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7128)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 222, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 654)
[M::mem_pestat] mean and std.dev: (245.65, 118.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 821)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (111, 890, 1571)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4491)
[M::mem_pestat] mean and std.dev: (911.78, 851.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5951)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 470, 1567)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4213)
[M::mem_pestat] mean and std.dev: (819.81, 740.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5536)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701360 sequences (100000159 bp) in 1.527 CPU sec, 1.562 real sec...
[M::process] read 701532 sequences (100000153 bp) in 1.450 CPU sec, 1.452 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 282849, 29, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 239, 555)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1323)
[M::mem_pestat] mean and std.dev: (348.35, 241.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1707)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 224, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 658)
[M::mem_pestat] mean and std.dev: (247.36, 119.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 826)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (396, 695, 1474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3630)
[M::mem_pestat] mean and std.dev: (999.54, 902.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4708)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (277, 470, 877)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2077)
[M::mem_pestat] mean and std.dev: (554.38, 398.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2677)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702442 reads in 196.687 CPU sec, 6.286 real sec
[M::mem_process_seqs] Processed 701664 reads in 124.507 CPU sec, 4.003 real sec
sorting block 0, #reads = 1076424 mem = 536879012 peak = 599592960
[M::process] read 700464 sequences (100000092 bp) in 1.860 CPU sec, 1.907 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 282789, 21, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 380, 979)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2597)
[M::mem_pestat] mean and std.dev: (378.92, 341.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3406)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 225, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (248.31, 120.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (690, 1808, 2946)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7458)
[M::mem_pestat] mean and std.dev: (1588.10, 1207.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9714)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 840, 2198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6240)
[M::mem_pestat] mean and std.dev: (1288.64, 1644.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8261)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700282 sequences (100000240 bp) in 1.650 CPU sec, 1.656 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 282904, 21, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (302, 674, 2268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6200)
[M::mem_pestat] mean and std.dev: (1361.02, 1621.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8166)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 224, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (247.88, 120.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 830)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (44, 336, 1283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3761)
[M::mem_pestat] mean and std.dev: (380.78, 598.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5000)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 212, 523)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1253)
[M::mem_pestat] mean and std.dev: (336.87, 298.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1618)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 282686, 32, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 347, 1039)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2751)
[M::mem_pestat] mean and std.dev: (551.10, 563.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3607)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 226, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 665)
[M::mem_pestat] mean and std.dev: (249.19, 120.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 835)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (347, 553, 1216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2954)
[M::mem_pestat] mean and std.dev: (801.10, 780.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3925)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 374, 1490)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4000)
[M::mem_pestat] mean and std.dev: (782.64, 937.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5255)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701360 reads in 255.172 CPU sec, 8.214 real sec
[M::mem_process_seqs] Processed 701532 reads in 207.520 CPU sec, 6.734 real sec
[M::mem_process_seqs] Processed 700464 reads in 230.994 CPU sec, 7.519 real sec
sorting block 1, #reads = 1073406 mem = 536877663 peak = 753164288
[M::process] read 699648 sequences (100000267 bp) in 2.200 CPU sec, 2.312 real sec...
sorting block 2, #reads = 1073901 mem = 536882196 peak = 831684608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 282789, 28, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 251, 1420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3874)
[M::mem_pestat] mean and std.dev: (517.05, 621.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5101)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 227, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 669)
[M::mem_pestat] mean and std.dev: (250.74, 121.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 840)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (334, 693, 2286)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6190)
[M::mem_pestat] mean and std.dev: (1036.11, 1116.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8142)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 347, 1763)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4887)
[M::mem_pestat] mean and std.dev: (757.55, 819.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6449)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699548 sequences (100000200 bp) in 2.082 CPU sec, 2.141 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 282894, 23, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 450, 2030)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5664)
[M::mem_pestat] mean and std.dev: (1128.32, 1376.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7481)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 229, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 673)
[M::mem_pestat] mean and std.dev: (252.79, 122.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 845)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (598, 1351, 1761)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4087)
[M::mem_pestat] mean and std.dev: (1264.14, 793.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5250)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 351, 832)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2016)
[M::mem_pestat] mean and std.dev: (511.98, 391.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2608)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698824 sequences (100000023 bp) in 1.719 CPU sec, 1.723 real sec...
[M::mem_process_seqs] Processed 700282 reads in 186.279 CPU sec, 5.912 real sec
[M::mem_process_seqs] Processed 699648 reads in 134.272 CPU sec, 4.279 real sec
sorting block 3, #reads = 1073227 mem = 536877341 peak = 831684608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 282496, 21, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (267, 385, 929)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2253)
[M::mem_pestat] mean and std.dev: (575.28, 432.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2915)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 229, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 676)
[M::mem_pestat] mean and std.dev: (253.45, 123.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 849)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (298, 621, 1033)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2503)
[M::mem_pestat] mean and std.dev: (683.25, 578.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3238)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 283, 645)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1511)
[M::mem_pestat] mean and std.dev: (331.08, 230.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1944)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698570 sequences (100000006 bp) in 2.500 CPU sec, 2.565 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 283019, 28, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 495, 1525)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4167)
[M::mem_pestat] mean and std.dev: (853.15, 789.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5488)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 230, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (255.02, 124.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 861)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (367, 870, 1356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3334)
[M::mem_pestat] mean and std.dev: (854.52, 697.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4323)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 599, 687)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1593)
[M::mem_pestat] mean and std.dev: (505.17, 319.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2046)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697898 sequences (100000128 bp) in 2.149 CPU sec, 2.147 real sec...
[M::mem_process_seqs] Processed 699548 reads in 176.847 CPU sec, 5.588 real sec
sorting block 4, #reads = 1073564 mem = 536884324 peak = 873889792
[M::mem_process_seqs] Processed 698824 reads in 123.984 CPU sec, 3.931 real sec
[M::process] read 697788 sequences (100000187 bp) in 2.039 CPU sec, 2.099 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 281971, 35, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 790, 1206)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3280)
[M::mem_pestat] mean and std.dev: (911.69, 740.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4317)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 233, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (258.03, 125.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 538, 854)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2192)
[M::mem_pestat] mean and std.dev: (392.66, 361.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2861)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 406, 807)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2029)
[M::mem_pestat] mean and std.dev: (439.69, 335.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2640)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697888 sequences (100000176 bp) in 1.500 CPU sec, 1.496 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 281926, 29, 19)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 480, 1650)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4422)
[M::mem_pestat] mean and std.dev: (837.76, 810.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5808)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 231, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 686)
[M::mem_pestat] mean and std.dev: (255.87, 124.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 862)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (549, 1333, 2913)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7641)
[M::mem_pestat] mean and std.dev: (1647.32, 1417.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10005)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 251, 1694)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4688)
[M::mem_pestat] mean and std.dev: (681.67, 870.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6185)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697898 reads in 163.289 CPU sec, 5.178 real sec
sorting block 5, #reads = 1073817 mem = 536881636 peak = 873889792
[M::mem_process_seqs] Processed 698570 reads in 188.612 CPU sec, 6.006 real sec
sorting block 6, #reads = 1074001 mem = 536882825 peak = 919343104
[M::process] read 697798 sequences (100000105 bp) in 2.629 CPU sec, 2.702 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 281950, 27, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (259, 344, 998)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2476)
[M::mem_pestat] mean and std.dev: (609.10, 562.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3215)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 233, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (258.14, 126.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 635, 1918)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5302)
[M::mem_pestat] mean and std.dev: (1156.07, 1356.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6994)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 510, 1193)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3099)
[M::mem_pestat] mean and std.dev: (709.18, 680.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4052)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697612 sequences (100000052 bp) in 2.248 CPU sec, 2.248 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 281983, 23, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 364, 1448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3942)
[M::mem_pestat] mean and std.dev: (672.27, 815.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5189)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 233, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (257.88, 125.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (105, 664, 2094)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6072)
[M::mem_pestat] mean and std.dev: (1350.04, 1549.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8061)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 480, 1286)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3448)
[M::mem_pestat] mean and std.dev: (667.15, 586.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4529)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697788 reads in 210.768 CPU sec, 6.679 real sec
[M::mem_process_seqs] Processed 697888 reads in 234.450 CPU sec, 7.547 real sec
sorting block 7, #reads = 1072716 mem = 536884220 peak = 919343104
[M::process] read 697694 sequences (100000009 bp) in 2.220 CPU sec, 2.293 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 281313, 30, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 269, 757)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1977)
[M::mem_pestat] mean and std.dev: (402.91, 353.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2587)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 233, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (258.11, 126.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (357, 606, 1061)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2469)
[M::mem_pestat] mean and std.dev: (632.72, 502.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3173)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 488, 921)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2295)
[M::mem_pestat] mean and std.dev: (648.67, 530.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2982)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697374 sequences (100000027 bp) in 2.234 CPU sec, 2.241 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 281820, 17, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 378, 1167)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3143)
[M::mem_pestat] mean and std.dev: (646.92, 600.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4131)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 233, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (257.16, 124.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 863)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 514, 1311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3509)
[M::mem_pestat] mean and std.dev: (644.50, 517.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4608)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 462, 1266)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3350)
[M::mem_pestat] mean and std.dev: (766.58, 850.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4392)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 281786, 14, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 584, 1359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3639)
[M::mem_pestat] mean and std.dev: (837.48, 695.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4779)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 232, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (256.92, 124.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 863)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 451, 743)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1863)
[M::mem_pestat] mean and std.dev: (496.00, 457.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2423)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 293, 692)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1646)
[M::mem_pestat] mean and std.dev: (431.23, 316.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2123)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697798 reads in 298.662 CPU sec, 9.631 real sec
sorting block 8, #reads = 1072983 mem = 536878274 peak = 919343104
[M::mem_process_seqs] Processed 697694 reads in 235.885 CPU sec, 7.563 real sec
[M::mem_process_seqs] Processed 697612 reads in 263.600 CPU sec, 8.454 real sec
sorting block 9, #reads = 1072627 mem = 536878774 peak = 919343104
[M::process] read 697548 sequences (100000111 bp) in 3.135 CPU sec, 3.275 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 281419, 34, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 295, 525)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1253)
[M::mem_pestat] mean and std.dev: (271.00, 223.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1617)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 233, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (257.43, 124.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 762, 2023)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5667)
[M::mem_pestat] mean and std.dev: (1107.29, 1065.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7489)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 259, 551)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1319)
[M::mem_pestat] mean and std.dev: (349.03, 279.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1703)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697624 sequences (100000257 bp) in 2.558 CPU sec, 2.616 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 282110, 34, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 393, 971)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2599)
[M::mem_pestat] mean and std.dev: (476.70, 452.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3413)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 233, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (257.15, 124.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 863)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (129, 1488, 1854)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5304)
[M::mem_pestat] mean and std.dev: (1121.35, 814.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7029)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 266, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 904)
[M::mem_pestat] mean and std.dev: (309.15, 169.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1136)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697374 reads in 218.252 CPU sec, 6.928 real sec
[M::process] read 697472 sequences (100000291 bp) in 2.581 CPU sec, 2.620 real sec...
[M::mem_process_seqs] Processed 697548 reads in 151.511 CPU sec, 4.921 real sec
sorting block 10, #reads = 1072893 mem = 536884730 peak = 919343104
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281706, 19, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 344, 601)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1473)
[M::mem_pestat] mean and std.dev: (328.85, 282.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1909)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 233, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684)
[M::mem_pestat] mean and std.dev: (256.62, 124.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 859)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 459, 3228)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9322)
[M::mem_pestat] mean and std.dev: (2092.42, 3085.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14436)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 405, 1317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3553)
[M::mem_pestat] mean and std.dev: (744.91, 767.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4671)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697328 sequences (100000019 bp) in 2.433 CPU sec, 2.626 real sec...
[M::process] read 697248 sequences (100000160 bp) in 2.300 CPU sec, 2.296 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 282143, 29, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 316, 1256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3338)
[M::mem_pestat] mean and std.dev: (632.78, 716.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4379)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 232, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 681)
[M::mem_pestat] mean and std.dev: (256.23, 124.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 855)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 385, 871)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2137)
[M::mem_pestat] mean and std.dev: (506.43, 422.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2770)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 310, 526)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1188)
[M::mem_pestat] mean and std.dev: (317.49, 178.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1519)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697624 reads in 216.894 CPU sec, 7.053 real sec
sorting block 11, #reads = 1072598 mem = 536880155 peak = 919343104
[M::mem_process_seqs] Processed 697472 reads in 148.484 CPU sec, 4.833 real sec
sorting block 12, #reads = 1073477 mem = 536883757 peak = 929746944
[M::process] read 697084 sequences (100000174 bp) in 2.631 CPU sec, 2.722 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 281788, 14, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 733, 1662)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4526)
[M::mem_pestat] mean and std.dev: (958.91, 857.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5958)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 232, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (256.61, 124.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 856)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (93, 427, 1470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4224)
[M::mem_pestat] mean and std.dev: (858.14, 972.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5601)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (344, 422, 1629)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4199)
[M::mem_pestat] mean and std.dev: (877.19, 992.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5484)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697328 reads in 121.970 CPU sec, 4.023 real sec
[M::process] read 696870 sequences (100000109 bp) in 2.597 CPU sec, 2.694 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 281639, 14, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 346, 996)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2642)
[M::mem_pestat] mean and std.dev: (448.15, 365.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3465)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 234, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (257.77, 124.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (397, 531, 1675)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4231)
[M::mem_pestat] mean and std.dev: (857.29, 651.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5509)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 294, 1103)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2883)
[M::mem_pestat] mean and std.dev: (491.05, 472.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3773)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697022 sequences (100000067 bp) in 2.209 CPU sec, 2.219 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 281855, 16, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 275, 549)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1323)
[M::mem_pestat] mean and std.dev: (317.27, 258.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1710)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 233, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (257.20, 124.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 860)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (393, 580, 936)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2022)
[M::mem_pestat] mean and std.dev: (626.87, 464.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2565)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 273, 528)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1154)
[M::mem_pestat] mean and std.dev: (285.29, 128.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1467)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697084 reads in 240.916 CPU sec, 7.700 real sec
sorting block 13, #reads = 1073144 mem = 536893530 peak = 929746944
[M::mem_process_seqs] Processed 697248 reads in 264.627 CPU sec, 8.564 real sec
sorting block 14, #reads = 1073721 mem = 536881404 peak = 929746944
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 281616, 24, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 829, 884)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2156)
[M::mem_pestat] mean and std.dev: (599.52, 382.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2792)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 235, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (259.62, 126.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 873)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (315, 603, 1000)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2370)
[M::mem_pestat] mean and std.dev: (551.76, 369.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3055)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 390, 574)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1350)
[M::mem_pestat] mean and std.dev: (390.07, 272.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1738)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696178 sequences (100000184 bp) in 2.773 CPU sec, 2.857 real sec...
[M::process] read 695980 sequences (100000228 bp) in 1.929 CPU sec, 1.933 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281642, 12, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 433, 2275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6451)
[M::mem_pestat] mean and std.dev: (798.58, 984.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8539)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 235, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (258.47, 124.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (617, 1015, 1463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3155)
[M::mem_pestat] mean and std.dev: (979.64, 403.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4001)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 242, 520)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1230)
[M::mem_pestat] mean and std.dev: (334.59, 203.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1585)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696870 reads in 188.147 CPU sec, 6.044 real sec
[M::mem_process_seqs] Processed 697022 reads in 122.877 CPU sec, 4.016 real sec
sorting block 15, #reads = 1071255 mem = 536880612 peak = 929746944
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 281190, 16, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 412, 1553)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4277)
[M::mem_pestat] mean and std.dev: (565.51, 676.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5639)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 237, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (260.06, 125.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 873)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (496, 784, 1287)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2869)
[M::mem_pestat] mean and std.dev: (799.27, 498.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3660)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 842, 1891)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5179)
[M::mem_pestat] mean and std.dev: (947.09, 911.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6823)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695738 sequences (100000204 bp) in 2.498 CPU sec, 2.565 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 281416, 21, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 301, 1116)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2982)
[M::mem_pestat] mean and std.dev: (576.46, 626.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3915)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 695622 sequences (100000035 bp) in 2.210 CPU sec, 2.210 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (162, 238, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (261.41, 125.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 878)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (402, 558, 1414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3438)
[M::mem_pestat] mean and std.dev: (897.52, 752.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4450)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (410, 651, 2136)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5588)
[M::mem_pestat] mean and std.dev: (1215.19, 1280.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7314)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696178 reads in 180.595 CPU sec, 5.823 real sec
[M::mem_process_seqs] Processed 695980 reads in 123.291 CPU sec, 3.918 real sec
sorting block 16, #reads = 1071665 mem = 536881358 peak = 929746944
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 281602, 20, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 297, 760)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1884)
[M::mem_pestat] mean and std.dev: (420.47, 362.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2446)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 238, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697)
[M::mem_pestat] mean and std.dev: (261.63, 125.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 875)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (422, 667, 2395)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6341)
[M::mem_pestat] mean and std.dev: (1497.05, 1696.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8314)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 430, 909)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2405)
[M::mem_pestat] mean and std.dev: (634.29, 598.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3153)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695222 sequences (100000035 bp) in 2.595 CPU sec, 2.738 real sec...
[M::process] read 695072 sequences (100000036 bp) in 1.678 CPU sec, 1.679 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 281145, 36, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 853, 1299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3493)
[M::mem_pestat] mean and std.dev: (899.25, 788.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4590)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 239, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (261.93, 125.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 537, 1992)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5530)
[M::mem_pestat] mean and std.dev: (979.64, 1200.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7299)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 305, 905)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2347)
[M::mem_pestat] mean and std.dev: (543.46, 511.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3068)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695738 reads in 184.343 CPU sec, 5.988 real sec
sorting block 17, #reads = 1072427 mem = 536883481 peak = 929746944
[M::mem_process_seqs] Processed 695622 reads in 123.239 CPU sec, 4.065 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 280521, 31, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 242, 769)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1903)
[M::mem_pestat] mean and std.dev: (330.92, 308.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2470)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 240, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 703)
[M::mem_pestat] mean and std.dev: (263.00, 126.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 883)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (58, 231, 928)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2668)
[M::mem_pestat] mean and std.dev: (435.59, 505.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3538)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 326, 742)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1840)
[M::mem_pestat] mean and std.dev: (395.32, 349.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2389)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 18, #reads = 1071399 mem = 536882914 peak = 929746944
[M::process] read 694954 sequences (100000177 bp) in 2.723 CPU sec, 2.840 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 281121, 29, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 453, 1118)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2896)
[M::mem_pestat] mean and std.dev: (642.26, 640.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3785)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 241, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 710)
[M::mem_pestat] mean and std.dev: (264.66, 128.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 892)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (802, 2071, 2525)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5971)
[M::mem_pestat] mean and std.dev: (1949.72, 1288.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7694)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 415, 886)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2168)
[M::mem_pestat] mean and std.dev: (424.46, 270.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2809)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694794 sequences (100000088 bp) in 2.180 CPU sec, 2.180 real sec...
[M::mem_process_seqs] Processed 695222 reads in 193.943 CPU sec, 6.312 real sec
[M::mem_process_seqs] Processed 695072 reads in 131.576 CPU sec, 4.285 real sec
sorting block 19, #reads = 1071810 mem = 536886222 peak = 929746944
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 281109, 36, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 338, 1396)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3820)
[M::mem_pestat] mean and std.dev: (640.18, 643.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5032)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 242, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 716)
[M::mem_pestat] mean and std.dev: (265.49, 128.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 900)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (64, 393, 1181)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3415)
[M::mem_pestat] mean and std.dev: (718.69, 813.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4532)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 544, 1071)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2799)
[M::mem_pestat] mean and std.dev: (682.16, 565.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3663)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696256 sequences (100000091 bp) in 3.175 CPU sec, 3.314 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 280643, 24, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 318, 617)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1537)
[M::mem_pestat] mean and std.dev: (293.37, 182.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1997)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 243, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 717)
[M::mem_pestat] mean and std.dev: (266.38, 128.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 901)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 516, 1643)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4445)
[M::mem_pestat] mean and std.dev: (977.43, 956.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5846)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 438, 853)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2067)
[M::mem_pestat] mean and std.dev: (458.21, 292.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2674)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702876 sequences (100000078 bp) in 2.519 CPU sec, 2.522 real sec...
[M::mem_process_seqs] Processed 694954 reads in 212.045 CPU sec, 6.858 real sec
[M::mem_process_seqs] Processed 694794 reads in 144.127 CPU sec, 4.763 real sec
sorting block 20, #reads = 1071421 mem = 536883159 peak = 929746944
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 281309, 25, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 339, 760)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1924)
[M::mem_pestat] mean and std.dev: (412.55, 326.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2506)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 239, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 705)
[M::mem_pestat] mean and std.dev: (262.45, 127.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 886)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 717, 1655)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4527)
[M::mem_pestat] mean and std.dev: (1094.25, 943.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5963)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 326, 1384)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3654)
[M::mem_pestat] mean and std.dev: (736.27, 683.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4789)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702052 sequences (100000170 bp) in 3.011 CPU sec, 3.261 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 283080, 24, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 213, 311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 547)
[M::mem_pestat] mean and std.dev: (222.86, 86.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 665)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 221, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 656)
[M::mem_pestat] mean and std.dev: (245.75, 120.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 824)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (493, 1193, 1607)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3835)
[M::mem_pestat] mean and std.dev: (1107.22, 749.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4949)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 392, 598)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1330)
[M::mem_pestat] mean and std.dev: (408.26, 254.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1696)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701252 sequences (100000101 bp) in 1.888 CPU sec, 1.897 real sec...
[M::mem_process_seqs] Processed 696256 reads in 228.455 CPU sec, 7.470 real sec
[M::mem_process_seqs] Processed 702876 reads in 156.026 CPU sec, 5.074 real sec
sorting block 21, #reads = 1070341 mem = 536881571 peak = 929746944
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 283435, 17, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 301, 3723)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10815)
[M::mem_pestat] mean and std.dev: (2182.75, 3264.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 15239)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 223, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (248.03, 121.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 837)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 1496, 2047)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5699)
[M::mem_pestat] mean and std.dev: (1311.12, 1035.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7525)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 453, 2019)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5597)
[M::mem_pestat] mean and std.dev: (909.40, 935.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7386)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701392 sequences (100000135 bp) in 2.955 CPU sec, 3.166 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 283053, 22, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 472, 681)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1599)
[M::mem_pestat] mean and std.dev: (570.47, 408.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2204)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 225, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 670)
[M::mem_pestat] mean and std.dev: (249.96, 122.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 842)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 1073, 2379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6647)
[M::mem_pestat] mean and std.dev: (1364.77, 1213.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8781)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 388, 1144)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3096)
[M::mem_pestat] mean and std.dev: (792.27, 911.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4437)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701026 sequences (100000104 bp) in 2.265 CPU sec, 2.273 real sec...
[M::mem_process_seqs] Processed 702052 reads in 220.558 CPU sec, 7.264 real sec
sorting block 22, #reads = 1074660 mem = 536879450 peak = 929746944
[M::mem_process_seqs] Processed 701252 reads in 153.711 CPU sec, 5.358 real sec
sorting block 23, #reads = 1076691 mem = 536877417 peak = 929746944
[M::process] read 700802 sequences (100000181 bp) in 2.836 CPU sec, 3.004 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 283030, 20, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 382, 1074)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2924)
[M::mem_pestat] mean and std.dev: (658.19, 593.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3849)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 225, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (250.69, 122.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 847)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (348, 800, 1169)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2811)
[M::mem_pestat] mean and std.dev: (837.80, 653.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3632)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 253, 925)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2419)
[M::mem_pestat] mean and std.dev: (493.91, 494.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3166)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700186 sequences (100000154 bp) in 2.453 CPU sec, 2.456 real sec...
[M::mem_process_seqs] Processed 701026 reads in 125.927 CPU sec, 3.982 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 283377, 14, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 245, 473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1093)
[M::mem_pestat] mean and std.dev: (292.96, 206.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1403)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 225, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667)
[M::mem_pestat] mean and std.dev: (249.36, 121.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 838)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (322, 1126, 2011)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5389)
[M::mem_pestat] mean and std.dev: (1180.54, 1113.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7078)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 345, 1166)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3142)
[M::mem_pestat] mean and std.dev: (705.82, 775.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4130)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 283075, 49, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 687, 960)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2456)
[M::mem_pestat] mean and std.dev: (604.48, 439.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3204)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 227, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 677)
[M::mem_pestat] mean and std.dev: (252.12, 123.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 851)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (89, 506, 1751)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5075)
[M::mem_pestat] mean and std.dev: (784.62, 824.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6737)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 311, 490)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1074)
[M::mem_pestat] mean and std.dev: (327.94, 175.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1366)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701392 reads in 341.823 CPU sec, 10.960 real sec
[M::process] read 699942 sequences (100000094 bp) in 2.651 CPU sec, 2.666 real sec...
sorting block 24, #reads = 1076308 mem = 536883988 peak = 929746944
[M::mem_process_seqs] Processed 700802 reads in 182.643 CPU sec, 6.095 real sec
sorting block 25, #reads = 1076649 mem = 536880601 peak = 977055744
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 282777, 27, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 310, 913)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2391)
[M::mem_pestat] mean and std.dev: (528.43, 520.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3130)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 227, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 678)
[M::mem_pestat] mean and std.dev: (252.43, 123.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 852)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 538, 947)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2551)
[M::mem_pestat] mean and std.dev: (539.73, 525.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3353)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 368, 835)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2079)
[M::mem_pestat] mean and std.dev: (518.26, 439.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2701)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699122 sequences (100000173 bp) in 3.133 CPU sec, 3.308 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 282826, 27, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 432, 2083)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5771)
[M::mem_pestat] mean and std.dev: (1053.90, 1303.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7615)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 228, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684)
[M::mem_pestat] mean and std.dev: (253.56, 124.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 860)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (252, 830, 1959)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5373)
[M::mem_pestat] mean and std.dev: (1195.48, 1398.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7080)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 244, 694)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1728)
[M::mem_pestat] mean and std.dev: (347.61, 270.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2245)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698894 sequences (100000178 bp) in 2.380 CPU sec, 2.383 real sec...
[M::mem_process_seqs] Processed 700186 reads in 224.723 CPU sec, 7.367 real sec
[M::mem_process_seqs] Processed 699942 reads in 157.112 CPU sec, 5.017 real sec
sorting block 26, #reads = 1075144 mem = 536877746 peak = 977055744
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 282610, 25, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 321, 1162)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3090)
[M::mem_pestat] mean and std.dev: (737.46, 815.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4054)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 230, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (255.53, 125.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 865)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (837, 1255, 3428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8610)
[M::mem_pestat] mean and std.dev: (1891.04, 1662.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11201)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 302, 701)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1717)
[M::mem_pestat] mean and std.dev: (386.44, 372.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2225)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698244 sequences (100000041 bp) in 2.985 CPU sec, 3.137 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 281957, 26, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 280, 499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1203)
[M::mem_pestat] mean and std.dev: (303.86, 254.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1555)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 232, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (256.73, 126.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (831, 1038, 1493)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2817)
[M::mem_pestat] mean and std.dev: (996.16, 652.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3608)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (310, 731, 1594)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4162)
[M::mem_pestat] mean and std.dev: (806.38, 610.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5446)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698562 sequences (100000093 bp) in 2.476 CPU sec, 2.479 real sec...
[M::mem_process_seqs] Processed 699122 reads in 217.428 CPU sec, 6.928 real sec
[M::mem_process_seqs] Processed 698894 reads in 152.460 CPU sec, 4.914 real sec
sorting block 27, #reads = 1075605 mem = 536879822 peak = 977055744
[M::process] read 698582 sequences (100000181 bp) in 2.972 CPU sec, 3.082 real sec...
[M::process] read 698260 sequences (100000132 bp) in 2.089 CPU sec, 2.101 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 282105, 31, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 212, 533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1249)
[M::mem_pestat] mean and std.dev: (296.81, 236.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1607)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 233, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701)
[M::mem_pestat] mean and std.dev: (259.02, 127.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 882)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (433, 711, 1373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3253)
[M::mem_pestat] mean and std.dev: (824.14, 644.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4193)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 285, 583)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1381)
[M::mem_pestat] mean and std.dev: (336.77, 232.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1780)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698562 reads in 117.408 CPU sec, 3.757 real sec
sorting block 28, #reads = 1074515 mem = 536877929 peak = 977055744
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 282104, 22, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 338, 756)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1956)
[M::mem_pestat] mean and std.dev: (417.72, 363.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2556)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 233, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (258.35, 126.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 878)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 808, 3196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9100)
[M::mem_pestat] mean and std.dev: (2518.86, 3181.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 15244)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (270, 381, 1184)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3012)
[M::mem_pestat] mean and std.dev: (681.59, 684.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3926)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 281684, 22, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 408, 838)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2118)
[M::mem_pestat] mean and std.dev: (542.19, 441.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2758)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 232, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (257.70, 126.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 874)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (509, 1028, 1054)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2144)
[M::mem_pestat] mean and std.dev: (869.00, 573.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3164)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 337, 1296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3536)
[M::mem_pestat] mean and std.dev: (578.80, 495.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4656)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698244 reads in 332.200 CPU sec, 10.668 real sec
[M::process] read 698126 sequences (100000158 bp) in 2.601 CPU sec, 2.609 real sec...
sorting block 29, #reads = 1074406 mem = 536878976 peak = 977055744
[M::mem_process_seqs] Processed 698582 reads in 182.324 CPU sec, 6.090 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 282273, 26, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 760, 1696)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4784)
[M::mem_pestat] mean and std.dev: (893.64, 750.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6328)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 233, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (258.44, 127.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 875)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (353, 1108, 1200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2894)
[M::mem_pestat] mean and std.dev: (821.00, 587.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3741)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 389, 1156)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3006)
[M::mem_pestat] mean and std.dev: (714.46, 730.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3931)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698242 sequences (100000074 bp) in 3.202 CPU sec, 3.285 real sec...
[M::process] read 697988 sequences (100000091 bp) in 2.320 CPU sec, 2.319 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 281984, 27, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 262, 643)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1547)
[M::mem_pestat] mean and std.dev: (332.82, 186.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1999)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 233, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (258.66, 127.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 878)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (433, 495, 1215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2779)
[M::mem_pestat] mean and std.dev: (632.76, 436.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3561)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 334, 557)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1303)
[M::mem_pestat] mean and std.dev: (383.70, 236.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1676)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698126 reads in 203.689 CPU sec, 6.649 real sec
sorting block 30, #reads = 1074129 mem = 536884981 peak = 977055744
[M::mem_process_seqs] Processed 698260 reads in 226.297 CPU sec, 7.427 real sec
sorting block 31, #reads = 1074082 mem = 536886451 peak = 977055744
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 281938, 32, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 407, 743)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1795)
[M::mem_pestat] mean and std.dev: (496.05, 391.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2321)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 232, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (257.54, 126.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 1095, 2983)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8673)
[M::mem_pestat] mean and std.dev: (1859.78, 2494.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11839)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 442, 719)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1643)
[M::mem_pestat] mean and std.dev: (488.56, 328.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2105)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697764 sequences (100000113 bp) in 2.411 CPU sec, 2.522 real sec...
[M::process] read 697886 sequences (100000076 bp) in 1.800 CPU sec, 1.797 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 281960, 25, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 1094, 1394)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3760)
[M::mem_pestat] mean and std.dev: (875.65, 615.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4943)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 233, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (258.51, 127.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 875)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (539, 737, 1746)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4160)
[M::mem_pestat] mean and std.dev: (674.65, 356.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5367)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 324, 657)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1549)
[M::mem_pestat] mean and std.dev: (375.46, 262.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1995)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698242 reads in 195.503 CPU sec, 6.263 real sec
[M::mem_process_seqs] Processed 697988 reads in 134.778 CPU sec, 4.387 real sec
sorting block 32, #reads = 1074236 mem = 536880290 peak = 977055744
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 281461, 29, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 284, 1026)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2740)
[M::mem_pestat] mean and std.dev: (449.71, 430.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3597)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 233, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (257.60, 125.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 867)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 850, 1883)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5107)
[M::mem_pestat] mean and std.dev: (1050.68, 1061.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6719)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (266, 451, 1180)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3008)
[M::mem_pestat] mean and std.dev: (607.84, 578.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3922)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697996 sequences (100000187 bp) in 2.635 CPU sec, 2.745 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 281839, 35, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 333, 827)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2049)
[M::mem_pestat] mean and std.dev: (541.11, 471.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2660)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 231, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 681)
[M::mem_pestat] mean and std.dev: (255.32, 123.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 855)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (397, 1155, 2523)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6775)
[M::mem_pestat] mean and std.dev: (1243.43, 1011.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8901)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 386, 727)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1771)
[M::mem_pestat] mean and std.dev: (456.14, 393.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2293)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697626 sequences (100000128 bp) in 2.290 CPU sec, 2.295 real sec...
[M::mem_process_seqs] Processed 697764 reads in 198.328 CPU sec, 6.384 real sec
[M::mem_process_seqs] Processed 697886 reads in 136.075 CPU sec, 4.340 real sec
sorting block 33, #reads = 1072335 mem = 536880256 peak = 977055744
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 281994, 45, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 201, 730)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1908)
[M::mem_pestat] mean and std.dev: (349.88, 345.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2497)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 231, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 678)
[M::mem_pestat] mean and std.dev: (255.20, 123.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 851)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (436, 759, 1761)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4411)
[M::mem_pestat] mean and std.dev: (1047.46, 985.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5736)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 356, 910)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2270)
[M::mem_pestat] mean and std.dev: (501.39, 357.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2950)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697884 sequences (100000178 bp) in 3.383 CPU sec, 3.626 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 281790, 28, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 378, 1286)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3500)
[M::mem_pestat] mean and std.dev: (714.31, 740.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4607)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 231, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 678)
[M::mem_pestat] mean and std.dev: (255.33, 123.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 851)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 290, 698)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1780)
[M::mem_pestat] mean and std.dev: (341.92, 315.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2321)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 316, 493)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1043)
[M::mem_pestat] mean and std.dev: (333.68, 201.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1318)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697252 sequences (100000046 bp) in 2.360 CPU sec, 2.367 real sec...
[M::mem_process_seqs] Processed 697996 reads in 205.923 CPU sec, 6.539 real sec
sorting block 34, #reads = 1073027 mem = 536879040 peak = 977055744
[M::mem_process_seqs] Processed 697626 reads in 139.474 CPU sec, 4.555 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 282068, 21, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (126, 283, 605)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1563)
[M::mem_pestat] mean and std.dev: (335.46, 264.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2042)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 231, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 678)
[M::mem_pestat] mean and std.dev: (255.21, 123.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 851)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (62, 370, 954)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2738)
[M::mem_pestat] mean and std.dev: (466.11, 460.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3630)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (258, 417, 778)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1818)
[M::mem_pestat] mean and std.dev: (576.48, 430.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2338)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 35, #reads = 1073005 mem = 536883783 peak = 977055744
[M::process] read 697076 sequences (100000283 bp) in 3.048 CPU sec, 3.154 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 281352, 37, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 334, 1157)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3045)
[M::mem_pestat] mean and std.dev: (600.94, 599.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3989)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 234, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (257.44, 124.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 860)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (390, 823, 1702)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4326)
[M::mem_pestat] mean and std.dev: (1083.69, 1073.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5638)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 579, 2388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6662)
[M::mem_pestat] mean and std.dev: (1488.39, 1745.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8799)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696858 sequences (100000257 bp) in 2.350 CPU sec, 2.347 real sec...
[M::mem_process_seqs] Processed 697884 reads in 203.990 CPU sec, 6.616 real sec
[M::mem_process_seqs] Processed 697252 reads in 137.613 CPU sec, 4.363 real sec
sorting block 36, #reads = 1072833 mem = 536879091 peak = 977055744
[M::process] read 696914 sequences (100000013 bp) in 3.096 CPU sec, 3.184 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 281305, 41, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 344, 418)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 856)
[M::mem_pestat] mean and std.dev: (313.33, 179.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1075)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 234, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (257.57, 123.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 857)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (373, 575, 2250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6004)
[M::mem_pestat] mean and std.dev: (1214.27, 1306.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7881)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 382, 769)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1879)
[M::mem_pestat] mean and std.dev: (420.15, 364.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2434)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696858 reads in 111.811 CPU sec, 3.505 real sec
[M::process] read 696596 sequences (100000072 bp) in 2.498 CPU sec, 2.522 real sec...
sorting block 37, #reads = 1071607 mem = 536880287 peak = 977055744
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 281455, 29, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (349, 1146, 1945)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5137)
[M::mem_pestat] mean and std.dev: (1086.43, 963.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6733)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 234, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (257.83, 124.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 912, 3288)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9476)
[M::mem_pestat] mean and std.dev: (1709.59, 2093.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12570)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 578, 1733)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4687)
[M::mem_pestat] mean and std.dev: (1055.09, 975.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6164)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 281883, 35, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 438, 1211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3265)
[M::mem_pestat] mean and std.dev: (624.35, 723.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4292)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 234, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (258.42, 125.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 513, 2642)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7626)
[M::mem_pestat] mean and std.dev: (1398.94, 1925.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10118)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 516, 945)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2331)
[M::mem_pestat] mean and std.dev: (633.81, 489.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3024)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697076 reads in 308.079 CPU sec, 9.768 real sec
[M::process] read 696378 sequences (100000230 bp) in 2.675 CPU sec, 2.693 real sec...
[M::mem_process_seqs] Processed 696914 reads in 164.544 CPU sec, 5.224 real sec
sorting block 38, #reads = 1071962 mem = 536879494 peak = 977055744
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 281748, 19, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (276, 403, 1567)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4149)
[M::mem_pestat] mean and std.dev: (698.10, 816.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5440)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 236, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (260.51, 126.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 877)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (351, 898, 2602)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7104)
[M::mem_pestat] mean and std.dev: (1165.89, 1077.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9355)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 373, 778)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1894)
[M::mem_pestat] mean and std.dev: (506.65, 423.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2452)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696666 sequences (100000102 bp) in 2.601 CPU sec, 2.709 real sec...
[M::process] read 696020 sequences (100000293 bp) in 1.780 CPU sec, 1.785 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 282162, 24, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 319, 485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1009)
[M::mem_pestat] mean and std.dev: (303.85, 126.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1271)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 236, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (260.68, 126.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 877)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 448, 1276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3468)
[M::mem_pestat] mean and std.dev: (667.95, 676.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4564)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 288, 576)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1328)
[M::mem_pestat] mean and std.dev: (348.68, 234.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1704)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696596 reads in 192.521 CPU sec, 6.134 real sec
[M::mem_process_seqs] Processed 696378 reads in 131.270 CPU sec, 4.181 real sec
sorting block 39, #reads = 1071874 mem = 536879621 peak = 977055744
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 281717, 29, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 306, 933)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2391)
[M::mem_pestat] mean and std.dev: (506.10, 422.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3120)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 236, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (260.57, 126.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 877)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (284, 484, 969)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2339)
[M::mem_pestat] mean and std.dev: (555.93, 516.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3024)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 434, 946)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2426)
[M::mem_pestat] mean and std.dev: (477.72, 365.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3166)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695994 sequences (100000068 bp) in 2.522 CPU sec, 2.643 real sec...
[M::process] read 696086 sequences (100000267 bp) in 1.970 CPU sec, 1.966 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 281522, 29, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 597, 2460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6978)
[M::mem_pestat] mean and std.dev: (991.53, 1046.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9237)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 237, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (261.16, 126.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 878)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (101, 387, 1352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3854)
[M::mem_pestat] mean and std.dev: (526.36, 541.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5105)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 310, 1455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3965)
[M::mem_pestat] mean and std.dev: (738.59, 782.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5220)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696666 reads in 198.421 CPU sec, 6.386 real sec
sorting block 40, #reads = 1072635 mem = 536884164 peak = 977055744
[M::mem_process_seqs] Processed 696020 reads in 138.232 CPU sec, 4.513 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 281896, 26, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (258, 293, 531)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1077)
[M::mem_pestat] mean and std.dev: (327.61, 148.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1350)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 237, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (261.33, 126.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 878)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (537, 836, 1380)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3066)
[M::mem_pestat] mean and std.dev: (1034.88, 844.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4411)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (268, 371, 1614)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4306)
[M::mem_pestat] mean and std.dev: (826.35, 841.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5652)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696830 sequences (100000274 bp) in 3.422 CPU sec, 3.680 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 281179, 25, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 431, 964)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2496)
[M::mem_pestat] mean and std.dev: (706.35, 663.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3359)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 236, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 704)
[M::mem_pestat] mean and std.dev: (261.52, 127.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 885)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (378, 935, 1984)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5196)
[M::mem_pestat] mean and std.dev: (1060.46, 853.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6802)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (281, 416, 703)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1547)
[M::mem_pestat] mean and std.dev: (495.57, 322.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1969)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699164 sequences (100000038 bp) in 2.490 CPU sec, 2.484 real sec...
[M::mem_process_seqs] Processed 695994 reads in 214.904 CPU sec, 6.915 real sec
sorting block 41, #reads = 1072107 mem = 536879745 peak = 981438464
[M::mem_process_seqs] Processed 696086 reads in 150.054 CPU sec, 4.808 real sec
sorting block 42, #reads = 1071238 mem = 536881060 peak = 1035890688
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 282110, 26, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 420, 912)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2262)
[M::mem_pestat] mean and std.dev: (560.09, 466.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2937)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 236, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701)
[M::mem_pestat] mean and std.dev: (261.13, 128.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 881)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (20, 507, 1514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4502)
[M::mem_pestat] mean and std.dev: (800.70, 1078.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5996)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 443, 1154)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3112)
[M::mem_pestat] mean and std.dev: (686.71, 698.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4091)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703614 sequences (100000021 bp) in 3.641 CPU sec, 3.925 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 281860, 31, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 300, 738)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1836)
[M::mem_pestat] mean and std.dev: (420.30, 337.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2385)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 230, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (255.53, 125.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 865)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (108, 367, 1253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3543)
[M::mem_pestat] mean and std.dev: (802.81, 859.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4688)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 271, 607)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1419)
[M::mem_pestat] mean and std.dev: (352.23, 252.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1825)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702666 sequences (100000215 bp) in 2.340 CPU sec, 2.338 real sec...
[M::mem_process_seqs] Processed 696830 reads in 213.300 CPU sec, 6.807 real sec
[M::mem_process_seqs] Processed 699164 reads in 152.759 CPU sec, 4.836 real sec
sorting block 43, #reads = 1070910 mem = 536880150 peak = 1035890688
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 284136, 20, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 352, 631)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1533)
[M::mem_pestat] mean and std.dev: (305.90, 177.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1984)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 219, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 652)
[M::mem_pestat] mean and std.dev: (243.73, 118.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 819)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (559, 765, 1419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3139)
[M::mem_pestat] mean and std.dev: (1051.25, 848.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4445)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 262, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 931)
[M::mem_pestat] mean and std.dev: (299.11, 177.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1178)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703096 sequences (100000060 bp) in 2.980 CPU sec, 3.080 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 283252, 39, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 404, 2128)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5980)
[M::mem_pestat] mean and std.dev: (1191.40, 1261.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7906)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 221, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 659)
[M::mem_pestat] mean and std.dev: (246.11, 120.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 828)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (287, 593, 765)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1721)
[M::mem_pestat] mean and std.dev: (560.08, 385.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2199)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 337, 614)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1332)
[M::mem_pestat] mean and std.dev: (376.77, 236.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1691)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702700 sequences (100000194 bp) in 2.342 CPU sec, 2.347 real sec...
[M::mem_process_seqs] Processed 703614 reads in 200.723 CPU sec, 6.361 real sec
sorting block 44, #reads = 1074015 mem = 536879892 peak = 1035890688
[M::mem_process_seqs] Processed 702666 reads in 141.933 CPU sec, 4.538 real sec
[M::process] read 701452 sequences (100000038 bp) in 2.536 CPU sec, 2.618 real sec...
[M::process] read 701104 sequences (100000083 bp) in 2.187 CPU sec, 2.192 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 283359, 22, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 276, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (265.67, 101.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 825)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 225, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 670)
[M::mem_pestat] mean and std.dev: (249.06, 120.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 842)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (132, 1165, 1998)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5730)
[M::mem_pestat] mean and std.dev: (1187.50, 1149.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7596)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 445, 1505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4005)
[M::mem_pestat] mean and std.dev: (854.54, 812.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5255)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701452 reads in 120.470 CPU sec, 3.938 real sec
sorting block 45, #reads = 1076562 mem = 536885467 peak = 1035890688
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 283880, 24, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 256, 771)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1957)
[M::mem_pestat] mean and std.dev: (400.07, 328.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2550)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 221, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 656)
[M::mem_pestat] mean and std.dev: (245.73, 119.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 824)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (272, 662, 1350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3506)
[M::mem_pestat] mean and std.dev: (781.00, 633.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4584)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 351, 660)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1598)
[M::mem_pestat] mean and std.dev: (406.59, 313.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2067)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 283728, 30, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (314, 377, 706)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1490)
[M::mem_pestat] mean and std.dev: (396.33, 238.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1882)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 221, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 659)
[M::mem_pestat] mean and std.dev: (245.73, 119.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 828)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (488, 741, 1557)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3695)
[M::mem_pestat] mean and std.dev: (824.72, 645.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4764)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 688, 895)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2179)
[M::mem_pestat] mean and std.dev: (546.53, 309.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2821)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700718 sequences (100000276 bp) in 2.680 CPU sec, 2.685 real sec...
[M::mem_process_seqs] Processed 703096 reads in 327.838 CPU sec, 10.540 real sec
sorting block 46, #reads = 1076292 mem = 536879057 peak = 1052954624
[M::mem_process_seqs] Processed 702700 reads in 263.164 CPU sec, 8.512 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 283160, 18, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 436, 1093)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2835)
[M::mem_pestat] mean and std.dev: (809.00, 670.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3706)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 225, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 670)
[M::mem_pestat] mean and std.dev: (249.88, 121.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 842)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 765, 1504)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4144)
[M::mem_pestat] mean and std.dev: (928.89, 906.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5464)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 269, 872)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2158)
[M::mem_pestat] mean and std.dev: (489.92, 449.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2801)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699622 sequences (100000284 bp) in 3.168 CPU sec, 3.317 real sec...
[M::process] read 699486 sequences (100000214 bp) in 1.870 CPU sec, 1.871 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 282890, 23, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 477, 616)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1382)
[M::mem_pestat] mean and std.dev: (410.71, 251.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1765)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 227, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (251.53, 122.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 847)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (367, 844, 3811)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10699)
[M::mem_pestat] mean and std.dev: (2018.04, 2623.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14143)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 259, 1057)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2869)
[M::mem_pestat] mean and std.dev: (514.54, 530.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3775)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701104 reads in 208.796 CPU sec, 6.668 real sec
sorting block 47, #reads = 1075938 mem = 536879130 peak = 1052954624
[M::mem_process_seqs] Processed 700718 reads in 141.708 CPU sec, 4.502 real sec
sorting block 48, #reads = 1075580 mem = 536883355 peak = 1054482432
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 282442, 21, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 395, 1026)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2604)
[M::mem_pestat] mean and std.dev: (603.09, 483.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3393)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 231, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (254.91, 123.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 861)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (375, 697, 3908)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10974)
[M::mem_pestat] mean and std.dev: (2738.43, 3449.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16538)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 256, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 977)
[M::mem_pestat] mean and std.dev: (330.15, 220.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1245)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699004 sequences (100000271 bp) in 3.035 CPU sec, 3.167 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 282429, 16, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 344, 427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 837)
[M::mem_pestat] mean and std.dev: (329.75, 172.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1042)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 231, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (254.75, 124.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 861)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (453, 1353, 1735)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4299)
[M::mem_pestat] mean and std.dev: (1326.75, 1121.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5811)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 656, 1333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3553)
[M::mem_pestat] mean and std.dev: (933.59, 940.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4694)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698518 sequences (100000274 bp) in 2.311 CPU sec, 2.317 real sec...
[M::mem_process_seqs] Processed 699622 reads in 205.840 CPU sec, 6.612 real sec
[M::mem_process_seqs] Processed 699486 reads in 143.916 CPU sec, 4.589 real sec
sorting block 49, #reads = 1074981 mem = 536882647 peak = 1054482432
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 282198, 38, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (286, 832, 1399)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3625)
[M::mem_pestat] mean and std.dev: (802.34, 578.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4738)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 232, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 686)
[M::mem_pestat] mean and std.dev: (255.59, 123.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 862)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (591, 1061, 1929)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4605)
[M::mem_pestat] mean and std.dev: (1005.44, 673.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5943)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 467, 1745)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4741)
[M::mem_pestat] mean and std.dev: (795.52, 743.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6239)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698186 sequences (100000255 bp) in 3.168 CPU sec, 3.306 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 282808, 23, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 337, 723)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1709)
[M::mem_pestat] mean and std.dev: (321.82, 204.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2202)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 232, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (256.57, 124.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 439, 1124)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3090)
[M::mem_pestat] mean and std.dev: (589.27, 672.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4073)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (285, 579, 1402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3636)
[M::mem_pestat] mean and std.dev: (741.85, 738.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4753)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698166 sequences (100000285 bp) in 2.340 CPU sec, 2.343 real sec...
[M::mem_process_seqs] Processed 699004 reads in 201.289 CPU sec, 6.367 real sec
[M::mem_process_seqs] Processed 698518 reads in 140.054 CPU sec, 4.547 real sec
sorting block 50, #reads = 1074390 mem = 536880361 peak = 1054482432
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281879, 26, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 319, 2700)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7618)
[M::mem_pestat] mean and std.dev: (1156.92, 1389.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10077)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 233, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (257.66, 125.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 875)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (447, 1084, 1431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3399)
[M::mem_pestat] mean and std.dev: (889.23, 548.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4383)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 345, 708)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1740)
[M::mem_pestat] mean and std.dev: (391.69, 281.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2256)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698226 sequences (100000032 bp) in 3.514 CPU sec, 3.735 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 282375, 23, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 505, 1761)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4935)
[M::mem_pestat] mean and std.dev: (863.78, 1025.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6522)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 234, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (257.83, 124.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (403, 713, 1741)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4417)
[M::mem_pestat] mean and std.dev: (759.72, 574.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5755)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 290, 1019)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2697)
[M::mem_pestat] mean and std.dev: (566.94, 574.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3536)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697906 sequences (100000056 bp) in 2.380 CPU sec, 2.382 real sec...
[M::mem_process_seqs] Processed 698186 reads in 207.469 CPU sec, 6.678 real sec
sorting block 51, #reads = 1074665 mem = 536879308 peak = 1054482432
[M::mem_process_seqs] Processed 698166 reads in 143.454 CPU sec, 4.561 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 282193, 19, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 430, 692)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1690)
[M::mem_pestat] mean and std.dev: (468.76, 391.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2189)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 234, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (257.92, 125.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (26, 168, 3123)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9317)
[M::mem_pestat] mean and std.dev: (1174.89, 1518.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12414)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 262, 487)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1093)
[M::mem_pestat] mean and std.dev: (295.67, 209.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1396)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 52, #reads = 1074424 mem = 536879509 peak = 1054482432
[M::process] read 697552 sequences (100000039 bp) in 2.873 CPU sec, 2.960 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 281729, 31, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 275, 863)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2281)
[M::mem_pestat] mean and std.dev: (480.45, 550.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2990)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 234, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (258.74, 126.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 875)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (315, 402, 1514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3912)
[M::mem_pestat] mean and std.dev: (849.87, 996.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5111)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (288, 459, 1140)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2844)
[M::mem_pestat] mean and std.dev: (533.72, 345.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3696)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697910 sequences (100000095 bp) in 2.259 CPU sec, 2.262 real sec...
[M::mem_process_seqs] Processed 698226 reads in 210.789 CPU sec, 6.726 real sec
[M::mem_process_seqs] Processed 697906 reads in 147.335 CPU sec, 4.666 real sec
sorting block 53, #reads = 1073404 mem = 536880528 peak = 1054482432
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 282177, 36, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 413, 1398)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3666)
[M::mem_pestat] mean and std.dev: (810.00, 814.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4800)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 235, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697)
[M::mem_pestat] mean and std.dev: (259.11, 125.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 876)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (484, 1047, 1810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4462)
[M::mem_pestat] mean and std.dev: (1061.24, 833.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5788)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (331, 496, 1637)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4249)
[M::mem_pestat] mean and std.dev: (885.91, 865.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5555)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697760 sequences (100000259 bp) in 2.867 CPU sec, 2.946 real sec...
[M::process] read 697220 sequences (100000197 bp) in 2.260 CPU sec, 2.260 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 282354, 19, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (266, 546, 1088)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2732)
[M::mem_pestat] mean and std.dev: (575.86, 472.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3554)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 232, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684)
[M::mem_pestat] mean and std.dev: (256.04, 124.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 859)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (246, 563, 1950)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5358)
[M::mem_pestat] mean and std.dev: (1186.06, 1421.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7062)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 1003, 1499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4091)
[M::mem_pestat] mean and std.dev: (1018.13, 1081.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5387)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697552 reads in 199.050 CPU sec, 6.298 real sec
[M::mem_process_seqs] Processed 697910 reads in 142.649 CPU sec, 4.780 real sec
sorting block 54, #reads = 1073498 mem = 536876880 peak = 1054482432
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 282137, 16, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 312, 1150)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3036)
[M::mem_pestat] mean and std.dev: (582.50, 528.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3979)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 232, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 681)
[M::mem_pestat] mean and std.dev: (255.94, 123.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 855)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (474, 984, 2555)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6717)
[M::mem_pestat] mean and std.dev: (881.85, 670.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8798)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 391, 905)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2249)
[M::mem_pestat] mean and std.dev: (491.79, 427.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2921)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697302 sequences (100000288 bp) in 3.285 CPU sec, 3.454 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 281723, 24, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 421, 751)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1907)
[M::mem_pestat] mean and std.dev: (454.53, 309.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2485)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 234, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (257.75, 124.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (341, 547, 1060)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2498)
[M::mem_pestat] mean and std.dev: (679.17, 395.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3217)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (268, 450, 1421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3727)
[M::mem_pestat] mean and std.dev: (813.74, 672.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4880)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697270 sequences (100000160 bp) in 2.475 CPU sec, 2.476 real sec...
[M::mem_process_seqs] Processed 697760 reads in 213.914 CPU sec, 7.019 real sec
sorting block 55, #reads = 1073632 mem = 536880911 peak = 1054482432
[M::mem_process_seqs] Processed 697220 reads in 149.216 CPU sec, 4.799 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281474, 40, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 408, 1387)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3707)
[M::mem_pestat] mean and std.dev: (857.45, 929.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4867)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 233, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (257.24, 124.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 860)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (386, 641, 2136)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5636)
[M::mem_pestat] mean and std.dev: (1140.83, 1175.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7386)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 541, 1060)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2770)
[M::mem_pestat] mean and std.dev: (602.45, 513.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3625)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 56, #reads = 1073624 mem = 536878754 peak = 1054482432
[M::process] read 697414 sequences (100000045 bp) in 2.857 CPU sec, 2.954 real sec...
[M::process] read 697212 sequences (100000092 bp) in 1.840 CPU sec, 1.844 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 281402, 27, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 441, 799)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2013)
[M::mem_pestat] mean and std.dev: (539.32, 477.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2620)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 233, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (257.26, 124.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 860)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (396, 728, 1558)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3882)
[M::mem_pestat] mean and std.dev: (963.96, 737.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5044)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 271, 727)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1693)
[M::mem_pestat] mean and std.dev: (421.20, 364.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2176)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697302 reads in 214.675 CPU sec, 6.917 real sec
[M::mem_process_seqs] Processed 697270 reads in 148.535 CPU sec, 4.788 real sec
sorting block 57, #reads = 1073314 mem = 536879967 peak = 1054482432
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 281611, 23, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 375, 1172)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3180)
[M::mem_pestat] mean and std.dev: (685.81, 722.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4184)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 233, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (256.84, 124.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 856)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (519, 833, 1748)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4206)
[M::mem_pestat] mean and std.dev: (996.81, 813.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5435)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (388, 760, 2172)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5740)
[M::mem_pestat] mean and std.dev: (1149.41, 1003.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7524)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697472 sequences (100000042 bp) in 3.095 CPU sec, 3.190 real sec...
[M::process] read 696622 sequences (100000157 bp) in 2.060 CPU sec, 2.058 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 281444, 27, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 301, 816)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2050)
[M::mem_pestat] mean and std.dev: (370.77, 278.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2667)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 235, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (258.76, 125.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (525, 666, 1520)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3510)
[M::mem_pestat] mean and std.dev: (925.04, 696.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4505)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 430, 1574)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4348)
[M::mem_pestat] mean and std.dev: (915.36, 952.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5735)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697414 reads in 211.457 CPU sec, 6.772 real sec
[M::mem_process_seqs] Processed 697212 reads in 146.557 CPU sec, 4.663 real sec
sorting block 58, #reads = 1072367 mem = 536880534 peak = 1054482432
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 281732, 39, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 280, 985)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2561)
[M::mem_pestat] mean and std.dev: (522.10, 476.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3349)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 233, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (256.94, 124.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 860)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (275, 695, 733)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1649)
[M::mem_pestat] mean and std.dev: (577.44, 403.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2190)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 334, 950)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2516)
[M::mem_pestat] mean and std.dev: (503.13, 487.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3299)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696530 sequences (100000161 bp) in 2.988 CPU sec, 3.079 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 281102, 34, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 528, 1188)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3180)
[M::mem_pestat] mean and std.dev: (701.68, 630.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4176)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 235, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (257.64, 123.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 857)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (355, 1074, 1116)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2638)
[M::mem_pestat] mean and std.dev: (775.97, 508.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3399)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 323, 862)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2234)
[M::mem_pestat] mean and std.dev: (455.57, 340.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2920)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696664 sequences (100000180 bp) in 2.356 CPU sec, 2.362 real sec...
[M::mem_process_seqs] Processed 697472 reads in 210.318 CPU sec, 6.683 real sec
sorting block 59, #reads = 1071025 mem = 536878945 peak = 1054482432
[M::mem_process_seqs] Processed 696622 reads in 144.899 CPU sec, 4.730 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281844, 25, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 289, 553)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1263)
[M::mem_pestat] mean and std.dev: (339.08, 243.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1618)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 235, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (258.63, 124.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 865)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 915, 1881)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5115)
[M::mem_pestat] mean and std.dev: (974.68, 878.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6732)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 690, 1406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3806)
[M::mem_pestat] mean and std.dev: (893.43, 920.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5006)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697026 sequences (100000217 bp) in 2.960 CPU sec, 3.043 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 281905, 28, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 273, 750)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1954)
[M::mem_pestat] mean and std.dev: (488.96, 525.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2590)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 235, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (259.42, 125.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 873)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (466, 683, 1051)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2221)
[M::mem_pestat] mean and std.dev: (712.92, 604.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3132)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 329, 1307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3595)
[M::mem_pestat] mean and std.dev: (793.97, 1051.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5001)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696766 sequences (100000238 bp) in 2.520 CPU sec, 2.513 real sec...
[M::mem_process_seqs] Processed 696530 reads in 208.238 CPU sec, 6.718 real sec
sorting block 60, #reads = 1071712 mem = 536884505 peak = 1054482432
[M::mem_process_seqs] Processed 696664 reads in 146.095 CPU sec, 4.641 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 282506, 31, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 362, 798)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2020)
[M::mem_pestat] mean and std.dev: (536.92, 420.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2631)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 235, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697)
[M::mem_pestat] mean and std.dev: (259.61, 126.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 876)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (335, 676, 1834)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4832)
[M::mem_pestat] mean and std.dev: (1030.94, 993.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6331)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 261, 379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (260.46, 109.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 958)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 61, #reads = 1072320 mem = 536884139 peak = 1106886656
[M::process] read 696828 sequences (100000127 bp) in 3.715 CPU sec, 4.016 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 281654, 26, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 281, 1178)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3108)
[M::mem_pestat] mean and std.dev: (565.53, 628.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4073)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 235, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (260.02, 126.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 877)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (51, 696, 1163)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3387)
[M::mem_pestat] mean and std.dev: (652.12, 683.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4499)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 391, 979)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2463)
[M::mem_pestat] mean and std.dev: (497.90, 394.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3205)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697026 reads in 214.538 CPU sec, 6.799 real sec
[M::process] read 696650 sequences (100000243 bp) in 2.469 CPU sec, 2.478 real sec...
[M::mem_process_seqs] Processed 696766 reads in 155.437 CPU sec, 5.122 real sec
sorting block 62, #reads = 1071180 mem = 536880288 peak = 1106886656
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 281882, 39, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (246, 460, 896)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2196)
[M::mem_pestat] mean and std.dev: (491.73, 300.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2846)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 235, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697)
[M::mem_pestat] mean and std.dev: (259.67, 126.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 876)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 539, 1267)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3413)
[M::mem_pestat] mean and std.dev: (699.66, 703.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4486)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 272, 378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (259.15, 120.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 957)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696598 sequences (100000211 bp) in 3.729 CPU sec, 3.899 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 281833, 21, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 266, 1407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3877)
[M::mem_pestat] mean and std.dev: (615.88, 665.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5112)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 234, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (259.39, 126.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 869)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (266, 631, 1846)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5006)
[M::mem_pestat] mean and std.dev: (807.60, 705.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6586)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 391, 1559)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4213)
[M::mem_pestat] mean and std.dev: (864.26, 922.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5540)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696828 reads in 205.684 CPU sec, 6.743 real sec
[M::process] read 697914 sequences (100000133 bp) in 2.672 CPU sec, 2.707 real sec...
[M::mem_process_seqs] Processed 696650 reads in 147.044 CPU sec, 4.767 real sec
sorting block 63, #reads = 1071918 mem = 536883256 peak = 1106886656
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 281420, 24, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 340, 708)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1808)
[M::mem_pestat] mean and std.dev: (439.09, 335.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2358)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 235, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (259.46, 126.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 873)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 502, 2511)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7113)
[M::mem_pestat] mean and std.dev: (1499.38, 1743.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9414)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (279, 397, 896)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2130)
[M::mem_pestat] mean and std.dev: (623.44, 556.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2851)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703046 sequences (100000163 bp) in 3.477 CPU sec, 3.648 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 282187, 25, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (249, 402, 907)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2223)
[M::mem_pestat] mean and std.dev: (583.68, 420.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2881)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 232, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684)
[M::mem_pestat] mean and std.dev: (256.31, 124.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 859)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (300, 433, 2299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6297)
[M::mem_pestat] mean and std.dev: (1125.12, 1288.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8296)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 363, 1524)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4196)
[M::mem_pestat] mean and std.dev: (626.17, 669.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5532)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702094 sequences (100000043 bp) in 2.451 CPU sec, 2.459 real sec...
[M::mem_process_seqs] Processed 696598 reads in 222.494 CPU sec, 7.187 real sec
sorting block 64, #reads = 1071015 mem = 536878411 peak = 1106886656
[M::mem_process_seqs] Processed 697914 reads in 157.353 CPU sec, 5.030 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 283564, 24, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 291, 1420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3764)
[M::mem_pestat] mean and std.dev: (614.97, 647.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4936)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 221, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 656)
[M::mem_pestat] mean and std.dev: (245.16, 118.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 824)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (453, 946, 1854)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4656)
[M::mem_pestat] mean and std.dev: (920.62, 625.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6057)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 308, 657)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1573)
[M::mem_pestat] mean and std.dev: (411.48, 336.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2031)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 65, #reads = 1068540 mem = 536876712 peak = 1106886656
[M::process] read 701710 sequences (100000209 bp) in 3.275 CPU sec, 3.366 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 283402, 23, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 560, 1848)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5176)
[M::mem_pestat] mean and std.dev: (934.41, 1115.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6840)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 224, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (248.46, 121.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 837)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (304, 540, 4283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12241)
[M::mem_pestat] mean and std.dev: (2202.43, 2861.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16220)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (277, 559, 1274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3268)
[M::mem_pestat] mean and std.dev: (754.92, 724.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4265)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703046 reads in 201.014 CPU sec, 6.439 real sec
[M::process] read 701708 sequences (100000088 bp) in 2.465 CPU sec, 2.480 real sec...
[M::mem_process_seqs] Processed 702094 reads in 147.845 CPU sec, 4.688 real sec
sorting block 66, #reads = 1074942 mem = 536882139 peak = 1106886656
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 282874, 20, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 390, 620)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1516)
[M::mem_pestat] mean and std.dev: (357.53, 241.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1964)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 224, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667)
[M::mem_pestat] mean and std.dev: (248.87, 121.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 838)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (74, 517, 1432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4148)
[M::mem_pestat] mean and std.dev: (676.95, 654.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5506)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 258, 493)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1079)
[M::mem_pestat] mean and std.dev: (299.43, 220.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1372)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701528 sequences (100000014 bp) in 3.312 CPU sec, 3.454 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 283327, 26, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 576, 1049)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2745)
[M::mem_pestat] mean and std.dev: (753.50, 675.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3593)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 225, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 670)
[M::mem_pestat] mean and std.dev: (249.06, 121.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 842)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 525, 738)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1784)
[M::mem_pestat] mean and std.dev: (580.32, 517.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2650)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 343, 829)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2107)
[M::mem_pestat] mean and std.dev: (539.65, 468.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2746)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701710 reads in 202.762 CPU sec, 6.451 real sec
[M::process] read 700656 sequences (100000275 bp) in 2.483 CPU sec, 2.492 real sec...
[M::mem_process_seqs] Processed 701708 reads in 143.272 CPU sec, 4.552 real sec
sorting block 67, #reads = 1076848 mem = 536882639 peak = 1106886656
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 283351, 42, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 253, 1256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3394)
[M::mem_pestat] mean and std.dev: (731.54, 806.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4463)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 225, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 670)
[M::mem_pestat] mean and std.dev: (249.78, 121.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 842)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (316, 884, 1908)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5092)
[M::mem_pestat] mean and std.dev: (1159.66, 1118.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6684)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (315, 858, 1656)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4338)
[M::mem_pestat] mean and std.dev: (1025.55, 913.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5679)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700650 sequences (100000161 bp) in 3.194 CPU sec, 3.318 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 282740, 29, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 503, 878)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2248)
[M::mem_pestat] mean and std.dev: (760.61, 735.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3703)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 227, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 677)
[M::mem_pestat] mean and std.dev: (251.88, 123.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 851)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (457, 993, 1326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3064)
[M::mem_pestat] mean and std.dev: (999.50, 750.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4003)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 792, 3491)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10041)
[M::mem_pestat] mean and std.dev: (1672.92, 2114.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13316)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700178 sequences (100000175 bp) in 2.380 CPU sec, 2.376 real sec...
[M::mem_process_seqs] Processed 701528 reads in 207.255 CPU sec, 6.608 real sec
sorting block 68, #reads = 1076858 mem = 536878672 peak = 1106886656
[M::mem_process_seqs] Processed 700656 reads in 144.037 CPU sec, 4.571 real sec
sorting block 69, #reads = 1075539 mem = 536880960 peak = 1106886656
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 283023, 26, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 479, 1235)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3271)
[M::mem_pestat] mean and std.dev: (672.90, 749.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4289)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 226, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (251.20, 122.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 847)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 451, 884)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2204)
[M::mem_pestat] mean and std.dev: (487.39, 400.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2864)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 362, 700)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1670)
[M::mem_pestat] mean and std.dev: (429.22, 349.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2155)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699578 sequences (100000081 bp) in 3.366 CPU sec, 3.554 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 283236, 28, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 329, 759)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1813)
[M::mem_pestat] mean and std.dev: (391.22, 252.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2340)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 228, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 681)
[M::mem_pestat] mean and std.dev: (253.11, 123.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 856)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (390, 424, 2562)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6906)
[M::mem_pestat] mean and std.dev: (1196.11, 1413.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9078)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 415, 1097)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2873)
[M::mem_pestat] mean and std.dev: (709.98, 769.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3788)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699358 sequences (100000097 bp) in 2.548 CPU sec, 2.554 real sec...
[M::mem_process_seqs] Processed 700650 reads in 209.488 CPU sec, 6.766 real sec
[M::mem_process_seqs] Processed 700178 reads in 144.047 CPU sec, 4.616 real sec
sorting block 70, #reads = 1076383 mem = 536883929 peak = 1106886656
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 281977, 30, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 291, 600)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1500)
[M::mem_pestat] mean and std.dev: (374.62, 320.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1950)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 230, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (254.72, 124.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (332, 496, 967)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2237)
[M::mem_pestat] mean and std.dev: (598.71, 509.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2872)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 271, 423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 881)
[M::mem_pestat] mean and std.dev: (295.51, 150.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1110)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699070 sequences (100000109 bp) in 3.102 CPU sec, 3.227 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 282864, 20, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 308, 668)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1552)
[M::mem_pestat] mean and std.dev: (351.22, 215.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1994)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 231, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (255.95, 125.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 869)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (409, 575, 2482)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6628)
[M::mem_pestat] mean and std.dev: (1021.67, 905.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8701)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (271, 570, 2591)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7231)
[M::mem_pestat] mean and std.dev: (1595.16, 2016.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9663)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698486 sequences (100000124 bp) in 2.460 CPU sec, 2.460 real sec...
[M::mem_process_seqs] Processed 699578 reads in 206.680 CPU sec, 6.599 real sec
[M::mem_process_seqs] Processed 699358 reads in 141.909 CPU sec, 4.593 real sec
sorting block 71, #reads = 1075693 mem = 536878343 peak = 1106886656
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 282590, 28, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 382, 767)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1953)
[M::mem_pestat] mean and std.dev: (503.18, 480.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2546)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 231, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (255.57, 124.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 865)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (363, 1011, 2435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6579)
[M::mem_pestat] mean and std.dev: (1732.50, 1645.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8651)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 424, 929)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2303)
[M::mem_pestat] mean and std.dev: (510.62, 440.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2990)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698688 sequences (100000135 bp) in 3.082 CPU sec, 3.254 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 282373, 20, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 421, 754)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1868)
[M::mem_pestat] mean and std.dev: (461.17, 381.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2425)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 233, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (257.20, 125.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (80, 177, 1671)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4853)
[M::mem_pestat] mean and std.dev: (583.94, 867.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6444)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 405, 1513)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4159)
[M::mem_pestat] mean and std.dev: (790.61, 791.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5482)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698238 sequences (100000062 bp) in 2.380 CPU sec, 2.386 real sec...
[M::mem_process_seqs] Processed 699070 reads in 203.985 CPU sec, 6.554 real sec
sorting block 72, #reads = 1074252 mem = 536882830 peak = 1106886656
[M::mem_process_seqs] Processed 698486 reads in 142.625 CPU sec, 4.554 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 282041, 38, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 254, 954)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2510)
[M::mem_pestat] mean and std.dev: (454.08, 398.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3288)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 233, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (257.04, 125.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 645, 1594)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4308)
[M::mem_pestat] mean and std.dev: (1064.16, 1021.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5665)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 335, 1136)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2966)
[M::mem_pestat] mean and std.dev: (704.78, 764.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3881)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 73, #reads = 1074425 mem = 536878094 peak = 1106886656
[M::process] read 698358 sequences (100000005 bp) in 3.416 CPU sec, 3.589 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 282429, 14, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 452, 885)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2175)
[M::mem_pestat] mean and std.dev: (601.58, 568.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2877)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 234, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (258.91, 126.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (81, 567, 1059)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3015)
[M::mem_pestat] mean and std.dev: (470.92, 461.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3993)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 360, 736)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1720)
[M::mem_pestat] mean and std.dev: (435.13, 305.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2212)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699020 sequences (100000270 bp) in 2.450 CPU sec, 2.448 real sec...
[M::mem_process_seqs] Processed 698688 reads in 210.608 CPU sec, 6.709 real sec
[M::mem_process_seqs] Processed 698238 reads in 144.463 CPU sec, 4.637 real sec
sorting block 74, #reads = 1074340 mem = 536881234 peak = 1106886656
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 281727, 35, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 598, 1621)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4449)
[M::mem_pestat] mean and std.dev: (901.38, 952.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5863)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 232, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (257.07, 125.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (446, 935, 2504)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6620)
[M::mem_pestat] mean and std.dev: (1526.66, 1429.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8678)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 315, 1006)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2512)
[M::mem_pestat] mean and std.dev: (561.52, 485.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3265)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698654 sequences (100000176 bp) in 3.238 CPU sec, 3.364 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 282450, 28, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 271, 639)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1587)
[M::mem_pestat] mean and std.dev: (392.13, 365.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2061)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 231, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (257.12, 126.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (28, 311, 2370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7054)
[M::mem_pestat] mean and std.dev: (1153.07, 1534.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9396)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 327, 1555)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4259)
[M::mem_pestat] mean and std.dev: (614.72, 603.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5611)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700652 sequences (100000224 bp) in 2.480 CPU sec, 2.475 real sec...
[M::mem_process_seqs] Processed 698358 reads in 207.766 CPU sec, 6.647 real sec
[M::mem_process_seqs] Processed 699020 reads in 143.424 CPU sec, 4.593 real sec
sorting block 75, #reads = 1073634 mem = 536878623 peak = 1106886656
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 282555, 27, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 394, 1754)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4864)
[M::mem_pestat] mean and std.dev: (950.49, 1182.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6419)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 231, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (256.44, 125.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (280, 580, 1660)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4420)
[M::mem_pestat] mean and std.dev: (1058.70, 1111.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5800)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 361, 1040)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2778)
[M::mem_pestat] mean and std.dev: (583.90, 555.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3647)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698426 sequences (100000158 bp) in 3.154 CPU sec, 3.251 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 283010, 21, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (126, 225, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 807)
[M::mem_pestat] mean and std.dev: (236.30, 143.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1034)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 224, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653)
[M::mem_pestat] mean and std.dev: (247.44, 119.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 819)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (348, 661, 1912)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5040)
[M::mem_pestat] mean and std.dev: (820.63, 697.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6604)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 289, 672)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1634)
[M::mem_pestat] mean and std.dev: (368.58, 306.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2115)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698390 sequences (100000107 bp) in 2.439 CPU sec, 2.444 real sec...
[M::mem_process_seqs] Processed 698654 reads in 210.040 CPU sec, 6.711 real sec
sorting block 76, #reads = 1073892 mem = 536883280 peak = 1106886656
[M::mem_process_seqs] Processed 700652 reads in 145.942 CPU sec, 4.639 real sec
sorting block 77, #reads = 1074125 mem = 536878574 peak = 1106886656
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281831, 15, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 277, 726)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1836)
[M::mem_pestat] mean and std.dev: (385.43, 363.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2391)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 230, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (254.50, 123.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 619, 840)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2114)
[M::mem_pestat] mean and std.dev: (643.67, 538.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2799)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 371, 1075)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2755)
[M::mem_pestat] mean and std.dev: (497.45, 438.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3595)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697830 sequences (100000034 bp) in 3.173 CPU sec, 3.265 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 281920, 30, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 393, 1106)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2776)
[M::mem_pestat] mean and std.dev: (595.94, 466.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3611)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 230, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (253.58, 122.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 846)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 569, 1559)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4239)
[M::mem_pestat] mean and std.dev: (903.00, 938.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5579)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 346, 1030)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2582)
[M::mem_pestat] mean and std.dev: (638.70, 579.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3358)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697616 sequences (100000204 bp) in 2.390 CPU sec, 2.384 real sec...
[M::mem_process_seqs] Processed 698426 reads in 215.718 CPU sec, 6.838 real sec
[M::mem_process_seqs] Processed 698390 reads in 151.943 CPU sec, 4.816 real sec
sorting block 78, #reads = 1073444 mem = 536876703 peak = 1106886656
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281662, 24, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 273, 726)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1794)
[M::mem_pestat] mean and std.dev: (309.88, 223.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2328)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 231, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 675)
[M::mem_pestat] mean and std.dev: (254.40, 122.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 847)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 701, 903)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2375)
[M::mem_pestat] mean and std.dev: (649.12, 466.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3111)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 293, 1531)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4219)
[M::mem_pestat] mean and std.dev: (723.41, 969.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5563)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697376 sequences (100000218 bp) in 3.098 CPU sec, 3.206 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 282139, 14, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 451, 1140)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3034)
[M::mem_pestat] mean and std.dev: (651.82, 602.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3981)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 232, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 678)
[M::mem_pestat] mean and std.dev: (255.22, 122.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 851)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 521, 884)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2192)
[M::mem_pestat] mean and std.dev: (676.57, 581.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3002)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 412, 1056)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2734)
[M::mem_pestat] mean and std.dev: (567.18, 589.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3573)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697640 sequences (100000273 bp) in 2.500 CPU sec, 2.502 real sec...
[M::mem_process_seqs] Processed 697830 reads in 217.126 CPU sec, 6.919 real sec
[M::mem_process_seqs] Processed 697616 reads in 151.762 CPU sec, 4.818 real sec
sorting block 79, #reads = 1069803 mem = 536879044 peak = 1106886656
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 281686, 28, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 363, 875)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2263)
[M::mem_pestat] mean and std.dev: (599.31, 562.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2957)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 232, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 676)
[M::mem_pestat] mean and std.dev: (255.44, 122.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 848)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 344, 1422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3930)
[M::mem_pestat] mean and std.dev: (828.29, 910.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5184)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 367, 1130)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3036)
[M::mem_pestat] mean and std.dev: (582.81, 632.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3989)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696910 sequences (100000181 bp) in 3.411 CPU sec, 3.544 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 281359, 36, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 420, 1186)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3028)
[M::mem_pestat] mean and std.dev: (703.67, 698.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3949)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 232, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 678)
[M::mem_pestat] mean and std.dev: (255.32, 122.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 851)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 614, 1624)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4454)
[M::mem_pestat] mean and std.dev: (744.84, 872.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5869)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 409, 926)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2314)
[M::mem_pestat] mean and std.dev: (568.62, 466.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3008)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697208 sequences (100000249 bp) in 2.503 CPU sec, 2.510 real sec...
[M::mem_process_seqs] Processed 697376 reads in 216.041 CPU sec, 6.853 real sec
sorting block 80, #reads = 1073370 mem = 536881217 peak = 1106886656
[M::mem_process_seqs] Processed 697640 reads in 150.136 CPU sec, 4.891 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 281677, 20, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 349, 912)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2370)
[M::mem_pestat] mean and std.dev: (497.43, 471.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3099)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 232, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 676)
[M::mem_pestat] mean and std.dev: (255.22, 121.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 848)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (123, 630, 1603)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4563)
[M::mem_pestat] mean and std.dev: (911.00, 888.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6043)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (262, 597, 1237)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3187)
[M::mem_pestat] mean and std.dev: (844.00, 714.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4162)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697132 sequences (100000294 bp) in 3.022 CPU sec, 3.159 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 281658, 21, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 342, 987)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2611)
[M::mem_pestat] mean and std.dev: (508.32, 466.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3423)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 233, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 673)
[M::mem_pestat] mean and std.dev: (254.91, 121.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 844)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (118, 734, 2927)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8545)
[M::mem_pestat] mean and std.dev: (1122.85, 1141.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11354)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 586, 1862)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5160)
[M::mem_pestat] mean and std.dev: (853.66, 881.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6809)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697136 sequences (100000191 bp) in 2.438 CPU sec, 2.449 real sec...
[M::mem_process_seqs] Processed 696910 reads in 211.834 CPU sec, 6.855 real sec
sorting block 81, #reads = 1071738 mem = 536878062 peak = 1106886656
[M::mem_process_seqs] Processed 697208 reads in 144.933 CPU sec, 4.638 real sec
sorting block 82, #reads = 1071439 mem = 536881906 peak = 1136766976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 281483, 35, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 516, 1025)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2643)
[M::mem_pestat] mean and std.dev: (632.50, 488.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3452)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 233, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 673)
[M::mem_pestat] mean and std.dev: (255.18, 120.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 844)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 498, 1500)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4016)
[M::mem_pestat] mean and std.dev: (771.06, 754.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5274)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 431, 819)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2001)
[M::mem_pestat] mean and std.dev: (515.00, 405.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2592)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696870 sequences (100000022 bp) in 3.270 CPU sec, 3.454 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 282051, 28, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 235, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1049)
[M::mem_pestat] mean and std.dev: (268.05, 194.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1349)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 233, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (256.50, 123.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 856)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (560, 755, 1530)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3470)
[M::mem_pestat] mean and std.dev: (887.88, 514.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4440)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 229, 576)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1354)
[M::mem_pestat] mean and std.dev: (384.14, 309.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1743)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696652 sequences (100000001 bp) in 2.450 CPU sec, 2.454 real sec...
[M::mem_process_seqs] Processed 697132 reads in 214.834 CPU sec, 6.843 real sec
[M::mem_process_seqs] Processed 697136 reads in 152.657 CPU sec, 4.834 real sec
sorting block 83, #reads = 1071151 mem = 536879224 peak = 1136766976
[M::process] read 696876 sequences (100000293 bp) in 2.538 CPU sec, 2.622 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 281763, 19, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 423, 907)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2235)
[M::mem_pestat] mean and std.dev: (597.51, 515.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2899)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 235, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 686)
[M::mem_pestat] mean and std.dev: (258.22, 124.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 861)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 301, 976)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2558)
[M::mem_pestat] mean and std.dev: (597.61, 612.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3349)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 272, 476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1062)
[M::mem_pestat] mean and std.dev: (280.88, 172.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1355)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696510 sequences (100000201 bp) in 2.322 CPU sec, 2.385 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 281203, 31, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 403, 573)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1301)
[M::mem_pestat] mean and std.dev: (332.59, 168.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1665)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 235, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (258.54, 125.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (363, 548, 1379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3411)
[M::mem_pestat] mean and std.dev: (816.64, 839.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4427)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 323, 558)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1314)
[M::mem_pestat] mean and std.dev: (352.88, 200.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1692)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696870 reads in 210.249 CPU sec, 6.708 real sec
sorting block 84, #reads = 1071856 mem = 536879312 peak = 1136766976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 280908, 31, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 239, 519)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1267)
[M::mem_pestat] mean and std.dev: (329.40, 286.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1641)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 235, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (258.76, 125.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 865)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (31, 359, 657)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1909)
[M::mem_pestat] mean and std.dev: (393.79, 515.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2535)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 249, 478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1068)
[M::mem_pestat] mean and std.dev: (252.83, 152.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1363)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696876 reads in 235.600 CPU sec, 7.462 real sec
[M::process] read 696442 sequences (100000200 bp) in 2.516 CPU sec, 2.522 real sec...
[M::mem_process_seqs] Processed 696652 reads in 266.268 CPU sec, 8.545 real sec
sorting block 85, #reads = 1071564 mem = 536878473 peak = 1136766976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 281477, 42, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 548, 1617)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4387)
[M::mem_pestat] mean and std.dev: (716.48, 804.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5772)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 236, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (259.99, 126.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 873)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 628, 1470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4098)
[M::mem_pestat] mean and std.dev: (849.60, 865.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5412)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 304, 416)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (334.69, 141.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 917)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706080 sequences (100000163 bp) in 3.171 CPU sec, 3.300 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 281548, 31, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 368, 1127)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3009)
[M::mem_pestat] mean and std.dev: (656.71, 679.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3950)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 236, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (260.19, 126.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 877)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (93, 408, 1040)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2934)
[M::mem_pestat] mean and std.dev: (640.20, 711.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3881)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 286, 813)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2015)
[M::mem_pestat] mean and std.dev: (398.70, 304.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2616)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706620 sequences (100000293 bp) in 2.519 CPU sec, 2.528 real sec...
[M::mem_process_seqs] Processed 696510 reads in 212.688 CPU sec, 6.818 real sec
sorting block 86, #reads = 1070839 mem = 536878944 peak = 1136766976
[M::mem_process_seqs] Processed 696442 reads in 150.981 CPU sec, 4.807 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 284498, 21, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 348, 972)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2538)
[M::mem_pestat] mean and std.dev: (501.90, 522.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3321)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 211, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 613)
[M::mem_pestat] mean and std.dev: (234.35, 112.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 768)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 548, 1226)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3340)
[M::mem_pestat] mean and std.dev: (838.90, 860.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4397)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 379, 756)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1798)
[M::mem_pestat] mean and std.dev: (505.88, 362.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2319)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705700 sequences (100000034 bp) in 3.459 CPU sec, 3.635 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 285133, 18, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 750, 1378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3790)
[M::mem_pestat] mean and std.dev: (828.33, 716.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4996)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 209, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 606)
[M::mem_pestat] mean and std.dev: (232.69, 112.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 759)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (84, 415, 1517)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4383)
[M::mem_pestat] mean and std.dev: (591.75, 673.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5816)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 437, 1049)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2781)
[M::mem_pestat] mean and std.dev: (724.62, 684.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3647)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703736 sequences (100000034 bp) in 2.530 CPU sec, 2.534 real sec...
[M::mem_process_seqs] Processed 706080 reads in 227.332 CPU sec, 7.214 real sec
sorting block 87, #reads = 1071641 mem = 536880266 peak = 1136766976
[M::mem_process_seqs] Processed 706620 reads in 158.904 CPU sec, 5.055 real sec
sorting block 88, #reads = 1073670 mem = 536880223 peak = 1136766976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 284848, 26, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 486, 1251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3325)
[M::mem_pestat] mean and std.dev: (523.67, 461.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4362)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 211, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 616)
[M::mem_pestat] mean and std.dev: (235.41, 114.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 772)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (409, 920, 2175)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5707)
[M::mem_pestat] mean and std.dev: (1091.60, 867.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7473)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 460, 1397)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3869)
[M::mem_pestat] mean and std.dev: (1004.66, 1123.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5497)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703136 sequences (100000027 bp) in 2.827 CPU sec, 3.007 real sec...
[M::process] read 702150 sequences (100000236 bp) in 2.510 CPU sec, 2.509 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 284308, 30, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 390, 914)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2356)
[M::mem_pestat] mean and std.dev: (556.57, 504.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3077)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 216, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 639)
[M::mem_pestat] mean and std.dev: (241.48, 118.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 802)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (326, 504, 969)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2255)
[M::mem_pestat] mean and std.dev: (656.48, 535.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2898)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 245, 811)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2027)
[M::mem_pestat] mean and std.dev: (474.56, 435.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2635)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705700 reads in 227.321 CPU sec, 7.464 real sec
[M::mem_process_seqs] Processed 703736 reads in 153.719 CPU sec, 5.038 real sec
sorting block 89, #reads = 1074478 mem = 536878528 peak = 1136766976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 284193, 26, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 406, 1168)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3202)
[M::mem_pestat] mean and std.dev: (644.03, 575.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4219)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 218, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 649)
[M::mem_pestat] mean and std.dev: (243.86, 119.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 815)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (282, 535, 1980)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5376)
[M::mem_pestat] mean and std.dev: (1162.00, 1136.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7074)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 346, 932)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2350)
[M::mem_pestat] mean and std.dev: (601.98, 516.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3059)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701608 sequences (100000139 bp) in 3.231 CPU sec, 3.347 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 283814, 29, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 393, 1275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3351)
[M::mem_pestat] mean and std.dev: (743.89, 736.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4389)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 220, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 656)
[M::mem_pestat] mean and std.dev: (246.02, 121.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 824)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (119, 408, 799)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2159)
[M::mem_pestat] mean and std.dev: (410.72, 334.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2839)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 365, 602)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1442)
[M::mem_pestat] mean and std.dev: (388.40, 255.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1862)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701204 sequences (100000171 bp) in 2.587 CPU sec, 2.588 real sec...
[M::mem_process_seqs] Processed 703136 reads in 214.874 CPU sec, 6.921 real sec
[M::mem_process_seqs] Processed 702150 reads in 146.791 CPU sec, 4.723 real sec
sorting block 90, #reads = 1077209 mem = 536878385 peak = 1136766976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 284033, 9, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 517, 651)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1523)
[M::mem_pestat] mean and std.dev: (510.80, 347.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1959)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 221, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 663)
[M::mem_pestat] mean and std.dev: (247.70, 122.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 833)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 369, 1011)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2691)
[M::mem_pestat] mean and std.dev: (651.02, 648.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3531)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 700784 sequences (100000034 bp) in 2.684 CPU sec, 2.823 real sec...
[M::process] read 700586 sequences (100000001 bp) in 2.565 CPU sec, 2.569 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 283414, 20, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 356, 758)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1938)
[M::mem_pestat] mean and std.dev: (470.19, 344.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2528)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 223, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (249.09, 122.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (493, 1147, 2415)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6259)
[M::mem_pestat] mean and std.dev: (1427.60, 1110.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8181)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 307, 784)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1972)
[M::mem_pestat] mean and std.dev: (487.41, 395.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2566)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701608 reads in 216.096 CPU sec, 6.942 real sec
sorting block 91, #reads = 1075284 mem = 536882748 peak = 1136766976
[M::mem_process_seqs] Processed 701204 reads in 150.323 CPU sec, 4.802 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 283124, 25, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 265, 1100)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2946)
[M::mem_pestat] mean and std.dev: (619.39, 630.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3869)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 224, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 670)
[M::mem_pestat] mean and std.dev: (250.25, 123.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 842)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 521, 1632)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4490)
[M::mem_pestat] mean and std.dev: (653.68, 636.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5919)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 424, 1021)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2677)
[M::mem_pestat] mean and std.dev: (591.85, 598.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3505)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 92, #reads = 1075289 mem = 536879973 peak = 1136766976
[M::process] read 699944 sequences (100000124 bp) in 3.314 CPU sec, 3.434 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 282866, 23, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 314, 1482)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4122)
[M::mem_pestat] mean and std.dev: (783.11, 901.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5442)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 225, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (251.35, 124.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 847)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (592, 995, 1830)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4306)
[M::mem_pestat] mean and std.dev: (1116.19, 790.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5544)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 550, 743)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1737)
[M::mem_pestat] mean and std.dev: (508.54, 384.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2234)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700784 reads in 215.458 CPU sec, 6.859 real sec
[M::process] read 700124 sequences (100000259 bp) in 2.699 CPU sec, 2.706 real sec...
[M::mem_process_seqs] Processed 700586 reads in 155.039 CPU sec, 5.123 real sec
sorting block 93, #reads = 1075042 mem = 536878502 peak = 1136766976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 282877, 29, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 316, 804)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2040)
[M::mem_pestat] mean and std.dev: (464.22, 363.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2658)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 227, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 678)
[M::mem_pestat] mean and std.dev: (252.79, 124.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 852)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 604, 1566)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4256)
[M::mem_pestat] mean and std.dev: (1014.86, 1113.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5601)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 408, 559)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1209)
[M::mem_pestat] mean and std.dev: (381.70, 211.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1534)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699856 sequences (100000209 bp) in 3.197 CPU sec, 3.323 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 283290, 37, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 326, 790)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1908)
[M::mem_pestat] mean and std.dev: (482.59, 371.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2467)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 226, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 677)
[M::mem_pestat] mean and std.dev: (252.00, 124.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 851)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (345, 906, 1431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3603)
[M::mem_pestat] mean and std.dev: (891.64, 708.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4689)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 301, 936)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2398)
[M::mem_pestat] mean and std.dev: (573.74, 566.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3129)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699322 sequences (100000218 bp) in 2.550 CPU sec, 2.557 real sec...
[M::mem_process_seqs] Processed 699944 reads in 221.675 CPU sec, 7.247 real sec
[M::mem_process_seqs] Processed 700124 reads in 152.405 CPU sec, 4.846 real sec
sorting block 94, #reads = 1073924 mem = 536878785 peak = 1136766976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 282628, 25, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 197, 1145)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3143)
[M::mem_pestat] mean and std.dev: (442.52, 569.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4142)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 227, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 681)
[M::mem_pestat] mean and std.dev: (253.47, 125.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 856)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 421, 1046)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2668)
[M::mem_pestat] mean and std.dev: (631.76, 570.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3479)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 332, 761)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1873)
[M::mem_pestat] mean and std.dev: (459.95, 372.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2429)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699084 sequences (100000276 bp) in 3.315 CPU sec, 3.446 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 282712, 37, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 227, 628)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1530)
[M::mem_pestat] mean and std.dev: (446.68, 439.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2205)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 228, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (253.72, 124.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 853)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (756, 938, 2012)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4524)
[M::mem_pestat] mean and std.dev: (1182.25, 928.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5780)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (277, 440, 1458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3820)
[M::mem_pestat] mean and std.dev: (765.31, 733.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5001)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698974 sequences (100000220 bp) in 2.544 CPU sec, 2.553 real sec...
[M::mem_process_seqs] Processed 699856 reads in 222.162 CPU sec, 7.071 real sec
sorting block 95, #reads = 1073576 mem = 536880618 peak = 1136766976
[M::mem_process_seqs] Processed 699322 reads in 157.844 CPU sec, 5.059 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 282431, 12, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 263, 1129)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3039)
[M::mem_pestat] mean and std.dev: (553.17, 645.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3994)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 230, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (255.27, 125.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 861)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (329, 778, 2640)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7262)
[M::mem_pestat] mean and std.dev: (1258.92, 1187.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9573)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 442, 791)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2039)
[M::mem_pestat] mean and std.dev: (517.43, 422.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2663)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 96, #reads = 1072447 mem = 536883488 peak = 1136766976
[M::process] read 698428 sequences (100000060 bp) in 3.339 CPU sec, 3.489 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 282225, 33, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 459, 836)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1980)
[M::mem_pestat] mean and std.dev: (547.66, 437.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2552)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 230, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (255.38, 125.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 861)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (304, 599, 1367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3493)
[M::mem_pestat] mean and std.dev: (626.90, 474.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4556)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 365, 1852)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5102)
[M::mem_pestat] mean and std.dev: (1144.04, 1346.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6727)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698366 sequences (100000258 bp) in 2.587 CPU sec, 2.589 real sec...
[M::mem_process_seqs] Processed 699084 reads in 228.949 CPU sec, 7.324 real sec
[M::mem_process_seqs] Processed 698974 reads in 162.127 CPU sec, 5.169 real sec
sorting block 97, #reads = 1071635 mem = 536882904 peak = 1136766976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 282427, 32, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (246, 397, 921)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2271)
[M::mem_pestat] mean and std.dev: (529.50, 437.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2946)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 230, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (255.64, 124.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (495, 798, 1643)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3939)
[M::mem_pestat] mean and std.dev: (879.79, 620.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5087)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 228, 557)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1349)
[M::mem_pestat] mean and std.dev: (299.07, 196.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1745)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698530 sequences (100000200 bp) in 3.069 CPU sec, 3.179 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 282372, 26, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 548, 1021)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2611)
[M::mem_pestat] mean and std.dev: (619.40, 518.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3406)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 231, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 686)
[M::mem_pestat] mean and std.dev: (256.29, 125.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 862)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (415, 540, 1175)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2695)
[M::mem_pestat] mean and std.dev: (734.28, 597.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3455)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 304, 567)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1337)
[M::mem_pestat] mean and std.dev: (370.72, 268.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1722)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698328 sequences (100000225 bp) in 2.520 CPU sec, 2.516 real sec...
[M::mem_process_seqs] Processed 698428 reads in 226.379 CPU sec, 7.212 real sec
[M::mem_process_seqs] Processed 698366 reads in 159.114 CPU sec, 5.071 real sec
sorting block 98, #reads = 1071139 mem = 536879341 peak = 1136766976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 282050, 27, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 547, 1030)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2696)
[M::mem_pestat] mean and std.dev: (598.21, 491.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3529)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 231, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (255.42, 124.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (495, 949, 1508)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3534)
[M::mem_pestat] mean and std.dev: (1095.04, 768.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4547)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (379, 717, 1161)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2725)
[M::mem_pestat] mean and std.dev: (589.71, 346.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3507)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697946 sequences (100000070 bp) in 3.480 CPU sec, 3.606 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 282400, 26, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 332, 661)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1529)
[M::mem_pestat] mean and std.dev: (437.26, 385.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1978)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 230, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (255.03, 124.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 706, 1395)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3701)
[M::mem_pestat] mean and std.dev: (812.56, 716.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4854)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 271, 987)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2515)
[M::mem_pestat] mean and std.dev: (520.44, 530.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3279)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698008 sequences (100000099 bp) in 2.425 CPU sec, 2.427 real sec...
[M::mem_process_seqs] Processed 698530 reads in 224.051 CPU sec, 7.117 real sec
sorting block 99, #reads = 1071011 mem = 536879393 peak = 1136766976
[M::mem_process_seqs] Processed 698328 reads in 157.215 CPU sec, 5.114 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 281897, 22, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 374, 919)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2379)
[M::mem_pestat] mean and std.dev: (540.09, 503.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3109)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 231, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 681)
[M::mem_pestat] mean and std.dev: (255.81, 124.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 855)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (519, 723, 2728)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7146)
[M::mem_pestat] mean and std.dev: (1714.64, 1854.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9355)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (294, 562, 1937)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5223)
[M::mem_pestat] mean and std.dev: (764.28, 953.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6866)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 100, #reads = 1070171 mem = 536881449 peak = 1136766976
[M::process] read 697856 sequences (100000037 bp) in 3.520 CPU sec, 3.752 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 281450, 16, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 339, 810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2068)
[M::mem_pestat] mean and std.dev: (508.39, 487.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2697)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 231, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 686)
[M::mem_pestat] mean and std.dev: (256.22, 125.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 862)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (80, 147, 473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1259)
[M::mem_pestat] mean and std.dev: (163.31, 149.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1652)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 336, 823)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2065)
[M::mem_pestat] mean and std.dev: (458.38, 381.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2686)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698108 sequences (100000034 bp) in 2.480 CPU sec, 2.477 real sec...
[M::mem_process_seqs] Processed 697946 reads in 228.114 CPU sec, 7.352 real sec
[M::mem_process_seqs] Processed 698008 reads in 155.339 CPU sec, 4.961 real sec
sorting block 101, #reads = 1069242 mem = 536877385 peak = 1136766976
[M::process] read 697706 sequences (100000254 bp) in 2.489 CPU sec, 2.565 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 281450, 17, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (131, 237, 479)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1175)
[M::mem_pestat] mean and std.dev: (265.64, 203.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1523)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 231, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 678)
[M::mem_pestat] mean and std.dev: (255.56, 124.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 851)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (289, 786, 1863)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5011)
[M::mem_pestat] mean and std.dev: (1265.41, 1320.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6585)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 359, 557)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1157)
[M::mem_pestat] mean and std.dev: (360.58, 198.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1457)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697800 sequences (100000181 bp) in 2.554 CPU sec, 2.565 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 282037, 24, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 541, 1492)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4120)
[M::mem_pestat] mean and std.dev: (969.74, 1040.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5434)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 231, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (255.51, 124.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (272, 825, 3427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9737)
[M::mem_pestat] mean and std.dev: (2052.50, 2711.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12900)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 488, 908)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2310)
[M::mem_pestat] mean and std.dev: (492.00, 357.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3011)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 281539, 17, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 340, 625)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1387)
[M::mem_pestat] mean and std.dev: (415.03, 297.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1768)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 232, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684)
[M::mem_pestat] mean and std.dev: (256.04, 123.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 859)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (90, 628, 1320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3780)
[M::mem_pestat] mean and std.dev: (859.71, 992.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5010)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (267, 382, 1872)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5082)
[M::mem_pestat] mean and std.dev: (933.17, 892.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6687)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697856 reads in 317.294 CPU sec, 10.165 real sec
[M::mem_process_seqs] Processed 698108 reads in 251.566 CPU sec, 8.064 real sec
sorting block 102, #reads = 1069792 mem = 536879317 peak = 1136766976
[M::process] read 697166 sequences (100000267 bp) in 3.406 CPU sec, 3.515 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 281609, 15, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 282, 755)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1839)
[M::mem_pestat] mean and std.dev: (363.31, 266.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2381)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 232, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684)
[M::mem_pestat] mean and std.dev: (256.39, 124.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 859)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (709, 714, 1272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2398)
[M::mem_pestat] mean and std.dev: (879.07, 548.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3074)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 359, 1394)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3702)
[M::mem_pestat] mean and std.dev: (743.09, 874.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4856)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697800 reads in 132.525 CPU sec, 4.250 real sec
sorting block 103, #reads = 1069562 mem = 536884302 peak = 1136766976
[M::process] read 697538 sequences (100000027 bp) in 3.155 CPU sec, 3.302 real sec...
[M::mem_process_seqs] Processed 697706 reads in 493.960 CPU sec, 15.846 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 282051, 22, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 207, 528)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1276)
[M::mem_pestat] mean and std.dev: (330.86, 293.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1650)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 233, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (257.92, 125.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (562, 1077, 1402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3082)
[M::mem_pestat] mean and std.dev: (927.44, 573.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3922)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 468, 1190)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3188)
[M::mem_pestat] mean and std.dev: (668.10, 681.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4187)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697706 sequences (100000264 bp) in 2.759 CPU sec, 3.191 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281876, 37, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 346, 1282)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3446)
[M::mem_pestat] mean and std.dev: (725.40, 806.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4528)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 233, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (256.59, 124.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 856)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (353, 626, 1949)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5141)
[M::mem_pestat] mean and std.dev: (1044.59, 843.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6737)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 447, 724)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1742)
[M::mem_pestat] mean and std.dev: (450.71, 353.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2251)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697166 reads in 256.844 CPU sec, 8.175 real sec
sorting block 104, #reads = 1067874 mem = 536879919 peak = 1136766976
[M::mem_process_seqs] Processed 697538 reads in 162.057 CPU sec, 5.129 real sec
[M::process] read 697282 sequences (100000173 bp) in 2.896 CPU sec, 2.982 real sec...
sorting block 105, #reads = 1069164 mem = 536882188 peak = 1136766976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 281618, 28, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 226, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 743)
[M::mem_pestat] mean and std.dev: (261.54, 150.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 942)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 232, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684)
[M::mem_pestat] mean and std.dev: (256.63, 124.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 859)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (372, 816, 1346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3294)
[M::mem_pestat] mean and std.dev: (969.61, 780.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4268)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 309, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 657)
[M::mem_pestat] mean and std.dev: (261.54, 80.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 801)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696918 sequences (100000034 bp) in 3.444 CPU sec, 3.602 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 281746, 18, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 279, 1377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3711)
[M::mem_pestat] mean and std.dev: (654.91, 619.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4878)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 233, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (258.08, 125.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (70, 411, 1325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3835)
[M::mem_pestat] mean and std.dev: (782.72, 826.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5090)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 366, 1292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3406)
[M::mem_pestat] mean and std.dev: (644.04, 623.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4463)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696998 sequences (100000067 bp) in 2.165 CPU sec, 2.170 real sec...
[M::mem_process_seqs] Processed 697706 reads in 231.533 CPU sec, 7.391 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 282184, 30, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 267, 521)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1245)
[M::mem_pestat] mean and std.dev: (300.86, 222.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1607)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 234, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 694)
[M::mem_pestat] mean and std.dev: (259.26, 126.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 872)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (538, 770, 1889)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4591)
[M::mem_pestat] mean and std.dev: (1212.53, 966.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5942)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 324, 607)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1421)
[M::mem_pestat] mean and std.dev: (418.50, 342.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1828)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708938 sequences (100000213 bp) in 2.752 CPU sec, 2.758 real sec...
[M::mem_process_seqs] Processed 696918 reads in 130.067 CPU sec, 4.121 real sec
sorting block 106, #reads = 1069253 mem = 536879960 peak = 1136766976
[M::mem_process_seqs] Processed 697282 reads in 331.504 CPU sec, 10.548 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 282081, 34, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (284, 436, 1106)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2750)
[M::mem_pestat] mean and std.dev: (648.38, 586.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3572)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 234, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 694)
[M::mem_pestat] mean and std.dev: (259.14, 126.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 872)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (387, 891, 1297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3117)
[M::mem_pestat] mean and std.dev: (781.16, 550.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4027)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (269, 512, 1221)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3125)
[M::mem_pestat] mean and std.dev: (726.31, 621.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4077)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 107, #reads = 1069100 mem = 536878452 peak = 1136766976
[M::process] read 708850 sequences (100000096 bp) in 3.677 CPU sec, 3.830 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 285334, 14, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 341, 697)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1697)
[M::mem_pestat] mean and std.dev: (374.32, 249.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2197)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 205, 293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 591)
[M::mem_pestat] mean and std.dev: (227.44, 108.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 740)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (401, 1105, 1680)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4238)
[M::mem_pestat] mean and std.dev: (987.77, 606.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5517)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 253, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 921)
[M::mem_pestat] mean and std.dev: (315.57, 166.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1154)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696998 reads in 271.081 CPU sec, 8.609 real sec
[M::process] read 708970 sequences (100000178 bp) in 2.750 CPU sec, 2.781 real sec...
[M::mem_process_seqs] Processed 708938 reads in 173.670 CPU sec, 5.500 real sec
sorting block 108, #reads = 1067466 mem = 536877170 peak = 1136766976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 285928, 26, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 225, 606)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1490)
[M::mem_pestat] mean and std.dev: (322.32, 254.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1932)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 204, 292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 588)
[M::mem_pestat] mean and std.dev: (226.98, 108.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 736)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 445, 893)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2307)
[M::mem_pestat] mean and std.dev: (515.60, 381.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3014)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (579, 1200, 1464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3234)
[M::mem_pestat] mean and std.dev: (867.57, 495.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4119)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708010 sequences (100000016 bp) in 3.499 CPU sec, 3.665 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 285959, 10, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 301, 1732)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4820)
[M::mem_pestat] mean and std.dev: (851.40, 999.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6364)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 204, 293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 589)
[M::mem_pestat] mean and std.dev: (227.79, 108.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 737)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (70, 533, 1270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3670)
[M::mem_pestat] mean and std.dev: (891.30, 1050.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5091)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 398, 1165)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3059)
[M::mem_pestat] mean and std.dev: (658.15, 682.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4006)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706178 sequences (100000215 bp) in 2.599 CPU sec, 2.600 real sec...
[M::mem_process_seqs] Processed 708850 reads in 243.949 CPU sec, 7.761 real sec
[M::mem_process_seqs] Processed 708970 reads in 171.980 CPU sec, 5.478 real sec
sorting block 109, #reads = 1073285 mem = 536887754 peak = 1136766976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 285471, 29, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (347, 606, 1176)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2834)
[M::mem_pestat] mean and std.dev: (722.44, 668.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3663)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 207, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 599)
[M::mem_pestat] mean and std.dev: (230.03, 110.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 750)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (285, 580, 2125)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5805)
[M::mem_pestat] mean and std.dev: (1138.75, 1235.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7645)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 263, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 990)
[M::mem_pestat] mean and std.dev: (287.66, 184.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1257)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705058 sequences (100000011 bp) in 3.605 CPU sec, 3.788 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 284997, 11, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 271, 1919)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5427)
[M::mem_pestat] mean and std.dev: (1016.14, 1219.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7181)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 210, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 613)
[M::mem_pestat] mean and std.dev: (234.52, 113.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 768)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 920, 4768)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13894)
[M::mem_pestat] mean and std.dev: (2183.82, 2900.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 18457)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 365, 2137)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5955)
[M::mem_pestat] mean and std.dev: (1039.36, 1117.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7864)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704494 sequences (100000001 bp) in 2.561 CPU sec, 2.566 real sec...
[M::mem_process_seqs] Processed 708010 reads in 257.552 CPU sec, 8.235 real sec
sorting block 110, #reads = 1071135 mem = 536886998 peak = 1136766976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 284724, 32, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (130, 339, 700)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1840)
[M::mem_pestat] mean and std.dev: (419.05, 335.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2410)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 213, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 623)
[M::mem_pestat] mean and std.dev: (237.20, 114.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 781)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (497, 1086, 2716)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7154)
[M::mem_pestat] mean and std.dev: (2009.75, 2222.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10901)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 343, 870)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2148)
[M::mem_pestat] mean and std.dev: (545.71, 465.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2787)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704418 sequences (100000041 bp) in 2.851 CPU sec, 2.852 real sec...
[M::mem_process_seqs] Processed 705058 reads in 138.534 CPU sec, 4.396 real sec
sorting block 111, #reads = 1070249 mem = 536878498 peak = 1136766976
[M::mem_process_seqs] Processed 706178 reads in 367.035 CPU sec, 11.721 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 284565, 25, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 480, 1380)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3848)
[M::mem_pestat] mean and std.dev: (850.23, 898.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5082)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 215, 310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 630)
[M::mem_pestat] mean and std.dev: (239.26, 115.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 790)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (522, 1330, 7275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 20781)
[M::mem_pestat] mean and std.dev: (2958.76, 3652.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 27534)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 375, 1146)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2982)
[M::mem_pestat] mean and std.dev: (696.71, 602.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3900)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703764 sequences (100000062 bp) in 3.360 CPU sec, 3.489 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 284872, 15, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 422, 1031)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2599)
[M::mem_pestat] mean and std.dev: (647.90, 591.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3383)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 214, 310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 630)
[M::mem_pestat] mean and std.dev: (239.66, 116.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 790)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (262, 333, 1734)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4678)
[M::mem_pestat] mean and std.dev: (923.86, 1112.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6150)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 415, 1649)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4597)
[M::mem_pestat] mean and std.dev: (917.69, 1060.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6071)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704494 reads in 272.310 CPU sec, 8.659 real sec
sorting block 112, #reads = 1070789 mem = 536880599 peak = 1136766976
[M::process] read 703224 sequences (100000287 bp) in 2.757 CPU sec, 2.792 real sec...
[M::mem_process_seqs] Processed 704418 reads in 171.532 CPU sec, 5.622 real sec
sorting block 113, #reads = 1070600 mem = 536885158 peak = 1136766976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 284476, 20, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 438, 1243)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3245)
[M::mem_pestat] mean and std.dev: (582.97, 646.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4246)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 216, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 639)
[M::mem_pestat] mean and std.dev: (241.81, 118.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 802)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (357, 538, 943)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2115)
[M::mem_pestat] mean and std.dev: (578.26, 463.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2701)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 502, 1046)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2810)
[M::mem_pestat] mean and std.dev: (596.12, 452.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3692)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702820 sequences (100000292 bp) in 3.491 CPU sec, 3.700 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 284188, 22, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 536, 1602)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4278)
[M::mem_pestat] mean and std.dev: (888.78, 883.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5616)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 218, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 649)
[M::mem_pestat] mean and std.dev: (243.93, 119.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 815)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (352, 938, 1791)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4669)
[M::mem_pestat] mean and std.dev: (1162.14, 1016.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6108)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 545, 1037)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2601)
[M::mem_pestat] mean and std.dev: (667.43, 530.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3383)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702478 sequences (100000290 bp) in 2.597 CPU sec, 2.606 real sec...
[M::mem_process_seqs] Processed 703764 reads in 239.617 CPU sec, 7.820 real sec
[M::mem_process_seqs] Processed 703224 reads in 163.552 CPU sec, 5.196 real sec
sorting block 114, #reads = 1070834 mem = 536878607 peak = 1136766976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 284056, 19, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 306, 543)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1273)
[M::mem_pestat] mean and std.dev: (341.81, 240.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1638)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 220, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 650)
[M::mem_pestat] mean and std.dev: (244.85, 119.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 816)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (131, 249, 1301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3641)
[M::mem_pestat] mean and std.dev: (580.83, 639.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4811)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 415, 2118)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5878)
[M::mem_pestat] mean and std.dev: (1078.83, 1201.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7758)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702206 sequences (100000245 bp) in 3.246 CPU sec, 3.415 real sec...
[M::process] read 701444 sequences (100000148 bp) in 1.960 CPU sec, 1.959 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 284304, 25, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 425, 813)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1981)
[M::mem_pestat] mean and std.dev: (518.48, 524.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2618)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 220, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653)
[M::mem_pestat] mean and std.dev: (245.53, 120.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 820)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 440, 2144)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6054)
[M::mem_pestat] mean and std.dev: (1069.71, 1280.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8009)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 466, 879)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2221)
[M::mem_pestat] mean and std.dev: (571.27, 445.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2892)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702820 reads in 232.173 CPU sec, 7.509 real sec
[M::mem_process_seqs] Processed 702478 reads in 159.186 CPU sec, 5.101 real sec
sorting block 115, #reads = 1072839 mem = 536878737 peak = 1136766976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 284046, 22, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 329, 1063)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2837)
[M::mem_pestat] mean and std.dev: (505.72, 560.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3724)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 221, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 659)
[M::mem_pestat] mean and std.dev: (246.38, 120.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 828)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 291, 761)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2017)
[M::mem_pestat] mean and std.dev: (432.65, 450.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2645)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 271, 1567)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4311)
[M::mem_pestat] mean and std.dev: (848.86, 974.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5683)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701576 sequences (100000292 bp) in 2.679 CPU sec, 2.779 real sec...
[M::process] read 701128 sequences (100000137 bp) in 2.276 CPU sec, 2.277 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 283022, 27, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 252, 900)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2292)
[M::mem_pestat] mean and std.dev: (586.04, 603.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3001)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 223, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (248.03, 121.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 830)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (115, 390, 1401)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3973)
[M::mem_pestat] mean and std.dev: (789.27, 980.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5259)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 365, 592)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1318)
[M::mem_pestat] mean and std.dev: (420.42, 276.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1681)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702206 reads in 234.924 CPU sec, 7.504 real sec
sorting block 116, #reads = 1072110 mem = 536879534 peak = 1136766976
[M::mem_process_seqs] Processed 701444 reads in 162.043 CPU sec, 5.209 real sec
sorting block 117, #reads = 1070958 mem = 536877609 peak = 1136766976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 283464, 34, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (283, 457, 1364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3526)
[M::mem_pestat] mean and std.dev: (852.09, 889.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4607)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 223, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (248.54, 121.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (100, 498, 1282)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3646)
[M::mem_pestat] mean and std.dev: (559.72, 586.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4828)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 605, 798)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1936)
[M::mem_pestat] mean and std.dev: (596.95, 504.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2616)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700384 sequences (100000236 bp) in 3.303 CPU sec, 3.434 real sec...
[M::process] read 699934 sequences (100000177 bp) in 2.278 CPU sec, 2.287 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 283131, 19, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (299, 414, 716)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1550)
[M::mem_pestat] mean and std.dev: (470.93, 313.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1967)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 224, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 673)
[M::mem_pestat] mean and std.dev: (250.70, 123.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 846)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (263, 588, 893)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2153)
[M::mem_pestat] mean and std.dev: (537.88, 395.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2783)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 405, 712)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1694)
[M::mem_pestat] mean and std.dev: (506.49, 431.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2231)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701576 reads in 232.802 CPU sec, 7.444 real sec
[M::mem_process_seqs] Processed 701128 reads in 161.445 CPU sec, 5.155 real sec
sorting block 118, #reads = 1071153 mem = 536882553 peak = 1136766976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 282555, 24, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 269, 949)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2517)
[M::mem_pestat] mean and std.dev: (493.30, 488.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3301)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 226, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (251.38, 123.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 847)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (463, 1488, 2242)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5800)
[M::mem_pestat] mean and std.dev: (1449.61, 1262.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7579)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 348, 929)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2327)
[M::mem_pestat] mean and std.dev: (520.39, 449.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3026)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698920 sequences (100000244 bp) in 3.191 CPU sec, 3.333 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 282806, 27, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 400, 990)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2568)
[M::mem_pestat] mean and std.dev: (504.00, 462.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3357)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 226, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 669)
[M::mem_pestat] mean and std.dev: (251.63, 122.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 840)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 283, 1015)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2677)
[M::mem_pestat] mean and std.dev: (683.41, 801.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3891)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 331, 953)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2443)
[M::mem_pestat] mean and std.dev: (552.29, 563.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3188)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699202 sequences (100000106 bp) in 2.650 CPU sec, 2.651 real sec...
[M::mem_process_seqs] Processed 700384 reads in 233.112 CPU sec, 7.434 real sec
[M::mem_process_seqs] Processed 699934 reads in 163.961 CPU sec, 5.235 real sec
sorting block 119, #reads = 1068984 mem = 536877702 peak = 1136766976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281881, 25, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 402, 763)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1971)
[M::mem_pestat] mean and std.dev: (488.05, 374.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2575)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 228, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (254.16, 124.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 853)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (412, 549, 1333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3175)
[M::mem_pestat] mean and std.dev: (854.88, 739.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4096)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (282, 874, 1842)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4962)
[M::mem_pestat] mean and std.dev: (1107.14, 991.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6522)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698314 sequences (100000043 bp) in 3.222 CPU sec, 3.359 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 282556, 39, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 351, 1364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3740)
[M::mem_pestat] mean and std.dev: (594.79, 678.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4928)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 228, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 673)
[M::mem_pestat] mean and std.dev: (252.81, 123.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 845)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (395, 856, 2068)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5414)
[M::mem_pestat] mean and std.dev: (1412.63, 1583.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7747)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 252, 548)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1228)
[M::mem_pestat] mean and std.dev: (333.77, 229.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1568)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698378 sequences (100000232 bp) in 2.620 CPU sec, 2.615 real sec...
[M::mem_process_seqs] Processed 698920 reads in 231.398 CPU sec, 7.397 real sec
sorting block 120, #reads = 1069867 mem = 536882253 peak = 1136766976
[M::mem_process_seqs] Processed 699202 reads in 161.187 CPU sec, 5.170 real sec
sorting block 121, #reads = 1069131 mem = 536878666 peak = 1136766976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 281632, 24, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 437, 2239)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6265)
[M::mem_pestat] mean and std.dev: (982.92, 1170.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8278)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 230, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (255.29, 124.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (492, 1331, 3893)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10695)
[M::mem_pestat] mean and std.dev: (2226.21, 2405.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14096)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 392, 731)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1819)
[M::mem_pestat] mean and std.dev: (510.79, 500.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2515)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698034 sequences (100000241 bp) in 3.207 CPU sec, 3.316 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281864, 35, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 1254, 2032)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5654)
[M::mem_pestat] mean and std.dev: (1069.06, 1165.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7465)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 230, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (255.49, 124.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (292, 599, 1160)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2896)
[M::mem_pestat] mean and std.dev: (834.34, 707.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3764)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 391, 1080)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2742)
[M::mem_pestat] mean and std.dev: (528.08, 432.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3573)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698380 sequences (100000041 bp) in 2.498 CPU sec, 2.503 real sec...
[M::mem_process_seqs] Processed 698314 reads in 229.503 CPU sec, 7.351 real sec
[M::mem_process_seqs] Processed 698378 reads in 159.548 CPU sec, 5.137 real sec
sorting block 122, #reads = 1069529 mem = 536882353 peak = 1136766976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 282357, 40, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 293, 1098)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2882)
[M::mem_pestat] mean and std.dev: (524.29, 481.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3774)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 231, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684)
[M::mem_pestat] mean and std.dev: (256.38, 125.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 859)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (321, 851, 1531)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3951)
[M::mem_pestat] mean and std.dev: (996.34, 1006.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5161)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 330, 502)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1152)
[M::mem_pestat] mean and std.dev: (323.93, 220.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1477)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698498 sequences (100000100 bp) in 3.295 CPU sec, 3.397 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 282033, 29, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 405, 946)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2422)
[M::mem_pestat] mean and std.dev: (515.00, 408.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3160)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 231, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (255.43, 124.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (313, 1140, 1600)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4174)
[M::mem_pestat] mean and std.dev: (824.92, 532.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5461)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 334, 856)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2220)
[M::mem_pestat] mean and std.dev: (523.50, 450.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2902)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697202 sequences (100000027 bp) in 2.590 CPU sec, 2.590 real sec...
[M::mem_process_seqs] Processed 698034 reads in 228.833 CPU sec, 7.343 real sec
[M::mem_process_seqs] Processed 698380 reads in 161.371 CPU sec, 5.140 real sec
sorting block 123, #reads = 1070850 mem = 536883130 peak = 1136766976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 281611, 22, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 365, 764)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1900)
[M::mem_pestat] mean and std.dev: (432.95, 348.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2468)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 230, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 677)
[M::mem_pestat] mean and std.dev: (254.55, 123.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 850)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (346, 1622, 1714)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4450)
[M::mem_pestat] mean and std.dev: (1079.60, 692.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5818)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 307, 764)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1870)
[M::mem_pestat] mean and std.dev: (374.41, 284.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2423)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696988 sequences (100000083 bp) in 3.343 CPU sec, 3.450 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 281313, 28, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 307, 499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1135)
[M::mem_pestat] mean and std.dev: (310.55, 200.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1453)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 234, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (258.36, 125.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 331, 993)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2709)
[M::mem_pestat] mean and std.dev: (511.56, 531.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3567)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 442, 1482)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3946)
[M::mem_pestat] mean and std.dev: (753.13, 838.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5178)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696808 sequences (100000162 bp) in 2.550 CPU sec, 2.550 real sec...
[M::mem_process_seqs] Processed 698498 reads in 225.896 CPU sec, 7.176 real sec
sorting block 124, #reads = 1069174 mem = 536877296 peak = 1136766976
[M::mem_process_seqs] Processed 697202 reads in 156.979 CPU sec, 4.992 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 281428, 35, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 433, 570)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1308)
[M::mem_pestat] mean and std.dev: (395.00, 243.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1677)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 235, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 694)
[M::mem_pestat] mean and std.dev: (258.90, 125.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 872)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 770, 1112)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3032)
[M::mem_pestat] mean and std.dev: (831.15, 850.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4232)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 444, 1063)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2853)
[M::mem_pestat] mean and std.dev: (551.40, 579.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3748)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 125, #reads = 1069874 mem = 536879077 peak = 1136766976
[M::process] read 697366 sequences (100000176 bp) in 3.609 CPU sec, 3.743 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 281544, 34, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 273, 521)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1237)
[M::mem_pestat] mean and std.dev: (319.79, 231.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1595)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 235, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (259.14, 126.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 869)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (314, 1104, 1516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3920)
[M::mem_pestat] mean and std.dev: (794.41, 662.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5122)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (265, 516, 757)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1741)
[M::mem_pestat] mean and std.dev: (498.71, 306.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2233)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697658 sequences (100000014 bp) in 2.050 CPU sec, 2.053 real sec...
[M::mem_process_seqs] Processed 696988 reads in 218.705 CPU sec, 6.958 real sec
[M::mem_process_seqs] Processed 696808 reads in 157.037 CPU sec, 5.250 real sec
sorting block 126, #reads = 1071067 mem = 536882646 peak = 1136766976
[M::process] read 699962 sequences (100000216 bp) in 3.533 CPU sec, 3.665 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 281743, 23, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 278, 814)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2068)
[M::mem_pestat] mean and std.dev: (466.95, 406.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2695)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 231, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684)
[M::mem_pestat] mean and std.dev: (256.74, 125.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 859)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (452, 859, 1746)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4334)
[M::mem_pestat] mean and std.dev: (1058.61, 889.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5628)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 328, 1861)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5271)
[M::mem_pestat] mean and std.dev: (965.85, 1143.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6976)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708290 sequences (100000018 bp) in 2.531 CPU sec, 2.539 real sec...
[M::mem_process_seqs] Processed 697658 reads in 139.030 CPU sec, 4.396 real sec
sorting block 127, #reads = 1068237 mem = 536878561 peak = 1136766976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 281674, 26, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 442, 1228)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3182)
[M::mem_pestat] mean and std.dev: (674.80, 676.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4159)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 233, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (258.13, 126.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 599, 1568)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4404)
[M::mem_pestat] mean and std.dev: (831.76, 922.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5822)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 492, 749)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1909)
[M::mem_pestat] mean and std.dev: (518.49, 398.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2489)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 282014, 26, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 272, 910)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2324)
[M::mem_pestat] mean and std.dev: (419.54, 372.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3031)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 225, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (250.68, 122.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 836)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (563, 1336, 1477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3305)
[M::mem_pestat] mean and std.dev: (1067.25, 652.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4219)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 311, 857)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2157)
[M::mem_pestat] mean and std.dev: (450.82, 408.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2807)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706568 sequences (100000113 bp) in 2.676 CPU sec, 2.680 real sec...
[M::mem_process_seqs] Processed 697366 reads in 372.876 CPU sec, 12.098 real sec
[M::mem_process_seqs] Processed 699962 reads in 212.611 CPU sec, 6.816 real sec
sorting block 128, #reads = 1067075 mem = 536886444 peak = 1136766976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 285990, 29, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 335, 1301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3589)
[M::mem_pestat] mean and std.dev: (628.92, 720.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4733)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 206, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 601)
[M::mem_pestat] mean and std.dev: (229.89, 110.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 753)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (332, 637, 1667)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4337)
[M::mem_pestat] mean and std.dev: (1033.68, 1104.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5672)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 209, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 669)
[M::mem_pestat] mean and std.dev: (215.44, 84.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 836)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705578 sequences (100000061 bp) in 3.337 CPU sec, 3.464 real sec...
[M::process] read 704414 sequences (100000107 bp) in 2.180 CPU sec, 2.182 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 285682, 18, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 258, 693)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1759)
[M::mem_pestat] mean and std.dev: (368.38, 331.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2292)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 211, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 621)
[M::mem_pestat] mean and std.dev: (235.20, 114.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 779)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (118, 682, 1237)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3475)
[M::mem_pestat] mean and std.dev: (867.89, 870.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4594)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 332, 797)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2041)
[M::mem_pestat] mean and std.dev: (483.15, 431.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2663)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 708290 reads in 227.173 CPU sec, 7.246 real sec
[M::mem_process_seqs] Processed 706568 reads in 155.490 CPU sec, 5.069 real sec
sorting block 129, #reads = 1069155 mem = 536878528 peak = 1136766976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 285287, 24, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 342, 843)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2203)
[M::mem_pestat] mean and std.dev: (512.53, 488.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2883)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 213, 308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 628)
[M::mem_pestat] mean and std.dev: (237.56, 115.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 788)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (334, 663, 1694)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4414)
[M::mem_pestat] mean and std.dev: (786.32, 698.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5774)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 248, 515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1201)
[M::mem_pestat] mean and std.dev: (277.52, 178.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1544)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703870 sequences (100000166 bp) in 4.036 CPU sec, 4.322 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 285144, 19, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 477, 880)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2270)
[M::mem_pestat] mean and std.dev: (533.17, 486.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2965)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 215, 311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 635)
[M::mem_pestat] mean and std.dev: (239.92, 116.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 797)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (303, 451, 4411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12627)
[M::mem_pestat] mean and std.dev: (2124.26, 2317.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16735)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 350, 800)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1900)
[M::mem_pestat] mean and std.dev: (443.84, 341.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2450)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705578 reads in 213.463 CPU sec, 6.919 real sec
[M::mem_process_seqs] Processed 704414 reads in 150.097 CPU sec, 4.746 real sec
[M::process] read 703332 sequences (100000213 bp) in 2.829 CPU sec, 2.905 real sec...
sorting block 130, #reads = 1078574 mem = 536879816 peak = 1136766976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 284383, 23, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 452, 863)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2303)
[M::mem_pestat] mean and std.dev: (474.54, 387.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3023)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 217, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 645)
[M::mem_pestat] mean and std.dev: (242.10, 117.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 810)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (514, 1331, 2127)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5353)
[M::mem_pestat] mean and std.dev: (1430.52, 1070.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6966)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (264, 429, 597)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1263)
[M::mem_pestat] mean and std.dev: (427.32, 206.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1596)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 131, #reads = 1077039 mem = 536878010 peak = 1136766976
[M::process] read 702328 sequences (100000063 bp) in 3.357 CPU sec, 3.490 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 284594, 21, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 487, 1072)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2848)
[M::mem_pestat] mean and std.dev: (650.75, 628.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3736)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 219, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 647)
[M::mem_pestat] mean and std.dev: (243.89, 118.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 812)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 498, 927)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2511)
[M::mem_pestat] mean and std.dev: (565.19, 518.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3303)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 350, 1166)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3178)
[M::mem_pestat] mean and std.dev: (630.83, 702.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4184)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703870 reads in 216.856 CPU sec, 6.924 real sec
[M::process] read 702118 sequences (100000015 bp) in 2.591 CPU sec, 2.637 real sec...
[M::mem_process_seqs] Processed 703332 reads in 152.597 CPU sec, 4.835 real sec
sorting block 132, #reads = 1077306 mem = 536879291 peak = 1136766976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 284379, 16, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 308, 516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1096)
[M::mem_pestat] mean and std.dev: (326.83, 193.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1386)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 221, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653)
[M::mem_pestat] mean and std.dev: (245.49, 119.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 820)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (551, 786, 2424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6170)
[M::mem_pestat] mean and std.dev: (1312.81, 1066.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8043)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (265, 617, 951)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2323)
[M::mem_pestat] mean and std.dev: (637.67, 478.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3009)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701546 sequences (100000034 bp) in 3.544 CPU sec, 3.711 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 283841, 26, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (272, 496, 1632)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4352)
[M::mem_pestat] mean and std.dev: (810.29, 653.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5712)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 221, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 657)
[M::mem_pestat] mean and std.dev: (246.30, 119.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 825)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (273, 417, 696)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1542)
[M::mem_pestat] mean and std.dev: (414.00, 237.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1965)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (121, 233, 810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2188)
[M::mem_pestat] mean and std.dev: (463.29, 439.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2877)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702328 reads in 213.905 CPU sec, 6.808 real sec
[M::process] read 700888 sequences (100000005 bp) in 2.508 CPU sec, 2.511 real sec...
[M::mem_process_seqs] Processed 702118 reads in 149.640 CPU sec, 4.738 real sec
sorting block 133, #reads = 1076793 mem = 536883097 peak = 1136766976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 284061, 24, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (277, 368, 694)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1528)
[M::mem_pestat] mean and std.dev: (417.06, 275.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1945)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 224, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (248.51, 120.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 471, 1103)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3021)
[M::mem_pestat] mean and std.dev: (596.96, 519.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3980)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 266, 870)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2272)
[M::mem_pestat] mean and std.dev: (530.46, 492.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2973)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700674 sequences (100000168 bp) in 3.468 CPU sec, 3.641 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 283637, 16, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 332, 902)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2312)
[M::mem_pestat] mean and std.dev: (477.73, 441.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3017)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 224, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 670)
[M::mem_pestat] mean and std.dev: (249.42, 121.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 842)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (532, 1208, 1367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3037)
[M::mem_pestat] mean and std.dev: (881.13, 534.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3872)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 253, 899)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2295)
[M::mem_pestat] mean and std.dev: (417.29, 405.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2993)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701480 sequences (100000063 bp) in 2.680 CPU sec, 2.680 real sec...
[M::mem_process_seqs] Processed 701546 reads in 230.220 CPU sec, 7.346 real sec
[M::mem_process_seqs] Processed 700888 reads in 163.216 CPU sec, 5.242 real sec
sorting block 134, #reads = 1075603 mem = 536885337 peak = 1136766976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 284038, 28, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (284, 439, 907)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2153)
[M::mem_pestat] mean and std.dev: (458.91, 298.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2776)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 225, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (249.93, 121.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 839)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 701, 974)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2544)
[M::mem_pestat] mean and std.dev: (588.08, 461.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3329)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 303, 511)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1165)
[M::mem_pestat] mean and std.dev: (324.60, 189.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1492)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 135, #reads = 1073402 mem = 536879875 peak = 1136766976
[M::process] read 701306 sequences (100000186 bp) in 3.352 CPU sec, 3.524 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 284045, 32, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 242, 1077)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2861)
[M::mem_pestat] mean and std.dev: (529.67, 502.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3753)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 224, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667)
[M::mem_pestat] mean and std.dev: (248.78, 121.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 838)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (309, 530, 1669)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4389)
[M::mem_pestat] mean and std.dev: (878.55, 965.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5749)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 553, 1119)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2933)
[M::mem_pestat] mean and std.dev: (734.30, 717.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3840)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700684 sequences (100000141 bp) in 2.553 CPU sec, 2.562 real sec...
[M::mem_process_seqs] Processed 700674 reads in 231.605 CPU sec, 7.437 real sec
[M::mem_process_seqs] Processed 701480 reads in 152.483 CPU sec, 4.848 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 283897, 25, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 237, 563)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1409)
[M::mem_pestat] mean and std.dev: (337.24, 269.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1832)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 224, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667)
[M::mem_pestat] mean and std.dev: (249.03, 121.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 838)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 509, 1633)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4471)
[M::mem_pestat] mean and std.dev: (706.14, 618.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5890)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 322, 2073)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5747)
[M::mem_pestat] mean and std.dev: (1129.68, 1284.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7584)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 136, #reads = 1074146 mem = 536883870 peak = 1136766976
[M::process] read 700146 sequences (100000148 bp) in 3.695 CPU sec, 3.984 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 283409, 22, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 638, 1118)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2966)
[M::mem_pestat] mean and std.dev: (632.83, 529.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3890)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 226, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (250.35, 121.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 839)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (273, 1216, 3329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9441)
[M::mem_pestat] mean and std.dev: (2040.32, 2073.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12497)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 330, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 954)
[M::mem_pestat] mean and std.dev: (329.16, 194.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1197)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701306 reads in 214.621 CPU sec, 6.846 real sec
[M::mem_process_seqs] Processed 700684 reads in 151.892 CPU sec, 4.798 real sec
[M::process] read 700082 sequences (100000064 bp) in 2.812 CPU sec, 2.888 real sec...
sorting block 137, #reads = 1074615 mem = 536878252 peak = 1136766976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 283099, 36, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 312, 611)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1399)
[M::mem_pestat] mean and std.dev: (383.82, 249.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1793)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 227, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (251.24, 121.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 847)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (272, 675, 2158)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5930)
[M::mem_pestat] mean and std.dev: (1100.83, 1122.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7816)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 207, 768)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2026)
[M::mem_pestat] mean and std.dev: (402.00, 433.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2655)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700756 sequences (100000246 bp) in 3.978 CPU sec, 4.247 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 283641, 28, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 266, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1072)
[M::mem_pestat] mean and std.dev: (289.45, 173.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1375)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 228, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 678)
[M::mem_pestat] mean and std.dev: (252.66, 123.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 852)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (398, 882, 1583)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3953)
[M::mem_pestat] mean and std.dev: (916.08, 792.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5138)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 290, 681)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1667)
[M::mem_pestat] mean and std.dev: (393.51, 352.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2160)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700146 reads in 216.956 CPU sec, 6.951 real sec
[M::mem_process_seqs] Processed 700082 reads in 153.230 CPU sec, 4.854 real sec
sorting block 138, #reads = 1075003 mem = 536880568 peak = 1136766976
[M::process] read 700418 sequences (100000272 bp) in 3.320 CPU sec, 3.466 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 283488, 22, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 324, 983)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2617)
[M::mem_pestat] mean and std.dev: (471.23, 405.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3434)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 225, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667)
[M::mem_pestat] mean and std.dev: (248.89, 120.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 838)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (333, 974, 1050)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2484)
[M::mem_pestat] mean and std.dev: (848.50, 539.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3201)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 267, 781)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1933)
[M::mem_pestat] mean and std.dev: (386.45, 355.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2509)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700072 sequences (100000103 bp) in 3.524 CPU sec, 3.780 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 282880, 25, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 373, 1222)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3248)
[M::mem_pestat] mean and std.dev: (680.51, 696.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4261)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 225, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (249.54, 121.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 839)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (890, 1265, 1828)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3704)
[M::mem_pestat] mean and std.dev: (1445.12, 1045.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5626)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 276, 740)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1852)
[M::mem_pestat] mean and std.dev: (455.72, 440.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2408)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700756 reads in 221.947 CPU sec, 7.069 real sec
sorting block 139, #reads = 1075174 mem = 536877251 peak = 1136766976
[M::mem_process_seqs] Processed 700418 reads in 156.495 CPU sec, 4.942 real sec
[M::process] read 699324 sequences (100000156 bp) in 2.854 CPU sec, 2.950 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 282965, 24, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 454, 747)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1863)
[M::mem_pestat] mean and std.dev: (456.46, 329.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2421)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 226, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 672)
[M::mem_pestat] mean and std.dev: (251.79, 122.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 844)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (39, 393, 1199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3519)
[M::mem_pestat] mean and std.dev: (548.50, 790.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4679)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 462, 1105)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2835)
[M::mem_pestat] mean and std.dev: (652.79, 561.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3700)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 140, #reads = 1073542 mem = 536879072 peak = 1136766976
[M::process] read 699804 sequences (100000058 bp) in 3.429 CPU sec, 3.566 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 282888, 20, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (246, 399, 643)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1437)
[M::mem_pestat] mean and std.dev: (462.43, 318.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1834)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 229, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (253.66, 123.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 853)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (114, 695, 1197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3363)
[M::mem_pestat] mean and std.dev: (643.05, 571.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4446)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 258, 663)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1603)
[M::mem_pestat] mean and std.dev: (415.16, 353.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2073)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699122 sequences (100000210 bp) in 2.432 CPU sec, 2.437 real sec...
[M::mem_process_seqs] Processed 700072 reads in 228.837 CPU sec, 7.288 real sec
[M::mem_process_seqs] Processed 699324 reads in 161.546 CPU sec, 5.315 real sec
sorting block 141, #reads = 1071163 mem = 536879118 peak = 1136766976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 282625, 41, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (267, 423, 1840)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4986)
[M::mem_pestat] mean and std.dev: (952.96, 1023.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6559)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 228, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 678)
[M::mem_pestat] mean and std.dev: (253.08, 123.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 852)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (278, 648, 946)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2282)
[M::mem_pestat] mean and std.dev: (576.82, 404.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2950)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (471, 966, 1649)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4005)
[M::mem_pestat] mean and std.dev: (978.21, 561.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5183)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698538 sequences (100000129 bp) in 2.651 CPU sec, 2.733 real sec...
[M::process] read 698908 sequences (100000002 bp) in 2.380 CPU sec, 2.376 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 282130, 21, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 274, 729)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1791)
[M::mem_pestat] mean and std.dev: (405.49, 352.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2322)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 229, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (254.38, 124.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 853)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (497, 767, 1398)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3200)
[M::mem_pestat] mean and std.dev: (964.95, 637.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4101)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 644, 1365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3731)
[M::mem_pestat] mean and std.dev: (766.98, 671.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4914)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699804 reads in 224.224 CPU sec, 7.316 real sec
sorting block 142, #reads = 1070989 mem = 536882351 peak = 1136766976
[M::mem_process_seqs] Processed 699122 reads in 156.609 CPU sec, 5.100 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 282176, 27, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 423, 756)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1954)
[M::mem_pestat] mean and std.dev: (439.52, 311.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2553)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 229, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (254.36, 123.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 853)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (278, 292, 2610)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7274)
[M::mem_pestat] mean and std.dev: (1323.00, 1673.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9606)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (272, 341, 479)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 893)
[M::mem_pestat] mean and std.dev: (333.32, 122.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1100)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698800 sequences (100000240 bp) in 2.931 CPU sec, 2.992 real sec...
[M::process] read 698290 sequences (100000236 bp) in 2.460 CPU sec, 2.468 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 282675, 24, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 459, 976)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2462)
[M::mem_pestat] mean and std.dev: (658.19, 586.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3205)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 228, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 673)
[M::mem_pestat] mean and std.dev: (252.95, 123.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 845)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (267, 1211, 1435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3771)
[M::mem_pestat] mean and std.dev: (1062.96, 832.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4939)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 605, 1584)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4336)
[M::mem_pestat] mean and std.dev: (1018.69, 1169.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5712)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698538 reads in 231.929 CPU sec, 7.470 real sec
sorting block 143, #reads = 1069844 mem = 536878919 peak = 1136766976
[M::mem_process_seqs] Processed 698908 reads in 160.915 CPU sec, 5.119 real sec
sorting block 144, #reads = 1069988 mem = 536877106 peak = 1151184896
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 282031, 18, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 304, 528)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1172)
[M::mem_pestat] mean and std.dev: (284.45, 154.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1494)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 228, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 670)
[M::mem_pestat] mean and std.dev: (252.65, 122.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 841)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (246, 348, 1651)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4461)
[M::mem_pestat] mean and std.dev: (711.50, 744.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5866)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 366, 969)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2489)
[M::mem_pestat] mean and std.dev: (543.40, 508.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3249)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698338 sequences (100000009 bp) in 3.188 CPU sec, 3.313 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 282332, 25, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 477, 951)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2435)
[M::mem_pestat] mean and std.dev: (557.34, 496.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3177)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 230, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (255.00, 123.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 483, 1276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3300)
[M::mem_pestat] mean and std.dev: (686.00, 618.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4312)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 396, 1255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3361)
[M::mem_pestat] mean and std.dev: (550.51, 604.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4414)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698032 sequences (100000073 bp) in 2.550 CPU sec, 2.558 real sec...
[M::mem_process_seqs] Processed 698800 reads in 231.538 CPU sec, 7.352 real sec
[M::mem_process_seqs] Processed 698290 reads in 159.848 CPU sec, 5.173 real sec
sorting block 145, #reads = 1068159 mem = 536878862 peak = 1151184896
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 282181, 19, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (354, 859, 1948)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5136)
[M::mem_pestat] mean and std.dev: (1124.12, 929.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6730)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 229, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 677)
[M::mem_pestat] mean and std.dev: (254.38, 123.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 850)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (395, 929, 1378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3344)
[M::mem_pestat] mean and std.dev: (726.24, 529.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4327)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 313, 1089)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2827)
[M::mem_pestat] mean and std.dev: (583.14, 554.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3696)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698112 sequences (100000112 bp) in 3.116 CPU sec, 3.235 real sec...
[M::process] read 697992 sequences (100000035 bp) in 2.450 CPU sec, 2.450 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 281125, 34, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 282, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (239.95, 109.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 880)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 231, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 681)
[M::mem_pestat] mean and std.dev: (255.86, 124.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 855)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (295, 937, 1594)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4192)
[M::mem_pestat] mean and std.dev: (933.80, 871.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5491)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 315, 905)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2301)
[M::mem_pestat] mean and std.dev: (526.96, 613.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2999)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698338 reads in 228.649 CPU sec, 7.345 real sec
[M::mem_process_seqs] Processed 698032 reads in 158.463 CPU sec, 5.148 real sec
sorting block 146, #reads = 1068963 mem = 536884665 peak = 1151184896
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 281631, 24, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 391, 618)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1492)
[M::mem_pestat] mean and std.dev: (373.13, 290.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1929)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 230, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (255.35, 124.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 499, 974)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2532)
[M::mem_pestat] mean and std.dev: (471.86, 422.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3311)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 230, 1164)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3186)
[M::mem_pestat] mean and std.dev: (549.03, 648.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4197)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698094 sequences (100000174 bp) in 3.220 CPU sec, 3.312 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 281817, 19, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 478, 1242)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3402)
[M::mem_pestat] mean and std.dev: (663.96, 620.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4482)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 230, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (255.21, 124.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (463, 463, 1293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2953)
[M::mem_pestat] mean and std.dev: (865.79, 719.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3783)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (304, 440, 958)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2266)
[M::mem_pestat] mean and std.dev: (540.68, 416.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2920)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699870 sequences (100000174 bp) in 2.650 CPU sec, 2.654 real sec...
[M::mem_process_seqs] Processed 698112 reads in 235.344 CPU sec, 7.580 real sec
sorting block 147, #reads = 1068052 mem = 536882440 peak = 1151184896
[M::mem_process_seqs] Processed 697992 reads in 162.334 CPU sec, 5.233 real sec
sorting block 148, #reads = 1066390 mem = 536880283 peak = 1151184896
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281939, 25, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 630, 1555)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4261)
[M::mem_pestat] mean and std.dev: (743.42, 763.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5614)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 231, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (255.37, 124.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 415, 807)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2023)
[M::mem_pestat] mean and std.dev: (507.05, 429.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2631)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 407, 568)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1232)
[M::mem_pestat] mean and std.dev: (364.82, 220.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1564)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 712364 sequences (100000192 bp) in 3.370 CPU sec, 3.467 real sec...
[M::process] read 710090 sequences (100000118 bp) in 2.560 CPU sec, 2.558 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 281964, 26, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (131, 251, 1050)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2888)
[M::mem_pestat] mean and std.dev: (691.19, 841.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4055)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 226, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (250.77, 122.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 836)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (110, 653, 1136)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3188)
[M::mem_pestat] mean and std.dev: (665.33, 697.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4214)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 391, 655)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1557)
[M::mem_pestat] mean and std.dev: (410.94, 330.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2008)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698094 reads in 261.175 CPU sec, 8.387 real sec
[M::mem_process_seqs] Processed 699870 reads in 191.076 CPU sec, 6.091 real sec
sorting block 149, #reads = 1062441 mem = 536878686 peak = 1151184896
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 286472, 23, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 201, 230)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (71, 336)
[M::mem_pestat] mean and std.dev: (177.00, 40.60)
[M::mem_pestat] low and high boundaries for proper pairs: (15, 389)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (141, 198, 281)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 561)
[M::mem_pestat] mean and std.dev: (219.28, 103.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 701)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (419, 641, 1014)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2204)
[M::mem_pestat] mean and std.dev: (604.50, 334.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2799)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 361, 1070)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2800)
[M::mem_pestat] mean and std.dev: (690.68, 685.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3665)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708570 sequences (100000249 bp) in 3.514 CPU sec, 3.734 real sec...
[M::process] read 707696 sequences (100000004 bp) in 1.950 CPU sec, 1.951 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 286473, 14, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 292, 816)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2062)
[M::mem_pestat] mean and std.dev: (475.00, 387.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2685)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 202, 290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 584)
[M::mem_pestat] mean and std.dev: (225.46, 107.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 731)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (303, 968, 1592)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4170)
[M::mem_pestat] mean and std.dev: (1132.38, 1199.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5930)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (290, 445, 1239)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3137)
[M::mem_pestat] mean and std.dev: (683.09, 556.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4086)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 712364 reads in 238.417 CPU sec, 7.565 real sec
[M::mem_process_seqs] Processed 710090 reads in 164.282 CPU sec, 5.249 real sec
sorting block 150, #reads = 1061839 mem = 536877475 peak = 1151184896
[M::process] read 706886 sequences (100000148 bp) in 2.917 CPU sec, 2.948 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 286081, 21, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 414, 996)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2684)
[M::mem_pestat] mean and std.dev: (464.57, 351.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3528)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 206, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 595)
[M::mem_pestat] mean and std.dev: (229.14, 110.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 745)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (130, 528, 1546)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4378)
[M::mem_pestat] mean and std.dev: (894.62, 1061.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5794)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 342, 911)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2259)
[M::mem_pestat] mean and std.dev: (586.64, 579.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2933)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 708570 reads in 137.433 CPU sec, 4.451 real sec
sorting block 151, #reads = 1071026 mem = 536881428 peak = 1151184896
[M::process] read 705888 sequences (100000212 bp) in 2.976 CPU sec, 3.039 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 285055, 25, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 490, 793)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1967)
[M::mem_pestat] mean and std.dev: (574.93, 484.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2554)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 210, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 618)
[M::mem_pestat] mean and std.dev: (234.46, 113.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 775)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (393, 643, 2204)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5826)
[M::mem_pestat] mean and std.dev: (1224.42, 1387.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7637)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 264, 847)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2145)
[M::mem_pestat] mean and std.dev: (532.74, 562.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2794)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705054 sequences (100000101 bp) in 2.240 CPU sec, 2.241 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 285266, 24, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 278, 1667)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4661)
[M::mem_pestat] mean and std.dev: (790.16, 1076.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6158)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 208, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 608)
[M::mem_pestat] mean and std.dev: (232.25, 111.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 762)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (107, 1132, 2228)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6470)
[M::mem_pestat] mean and std.dev: (1276.04, 1352.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8591)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 412, 1284)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3464)
[M::mem_pestat] mean and std.dev: (702.08, 691.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4554)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706886 reads in 264.907 CPU sec, 8.453 real sec
sorting block 152, #reads = 1070396 mem = 536879009 peak = 1151184896
[M::mem_process_seqs] Processed 707696 reads in 292.789 CPU sec, 9.373 real sec
[M::process] read 704376 sequences (100000036 bp) in 2.945 CPU sec, 3.012 real sec...
[M::process] read 704254 sequences (100000206 bp) in 2.447 CPU sec, 2.450 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 284248, 20, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 301, 491)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1069)
[M::mem_pestat] mean and std.dev: (365.09, 227.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1358)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 214, 309)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 629)
[M::mem_pestat] mean and std.dev: (238.38, 115.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 789)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 601, 1849)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5085)
[M::mem_pestat] mean and std.dev: (706.56, 639.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6703)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 251, 1185)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3191)
[M::mem_pestat] mean and std.dev: (593.63, 636.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4194)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705054 reads in 127.124 CPU sec, 4.153 real sec
sorting block 153, #reads = 1071189 mem = 536881399 peak = 1151184896
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 284233, 22, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 363, 1184)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3222)
[M::mem_pestat] mean and std.dev: (655.61, 697.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4241)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 212, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 625)
[M::mem_pestat] mean and std.dev: (236.68, 114.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 784)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (399, 864, 1077)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2433)
[M::mem_pestat] mean and std.dev: (692.76, 408.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3111)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 363, 1474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4046)
[M::mem_pestat] mean and std.dev: (744.18, 736.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5332)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 284222, 37, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 253, 426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 940)
[M::mem_pestat] mean and std.dev: (251.07, 134.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1197)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 215, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 639)
[M::mem_pestat] mean and std.dev: (240.65, 116.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 802)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (295, 951, 1392)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3586)
[M::mem_pestat] mean and std.dev: (964.38, 744.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4683)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 253, 947)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2555)
[M::mem_pestat] mean and std.dev: (476.60, 439.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3359)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703036 sequences (100000202 bp) in 2.102 CPU sec, 2.103 real sec...
[M::mem_process_seqs] Processed 705888 reads in 346.867 CPU sec, 11.142 real sec
sorting block 154, #reads = 1069164 mem = 536879036 peak = 1151184896
[M::mem_process_seqs] Processed 704376 reads in 275.542 CPU sec, 8.900 real sec
[M::process] read 703128 sequences (100000299 bp) in 2.412 CPU sec, 2.520 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 284314, 21, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 309, 1366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3738)
[M::mem_pestat] mean and std.dev: (635.64, 803.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4924)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 217, 314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 642)
[M::mem_pestat] mean and std.dev: (241.95, 117.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 806)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (280, 751, 1273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3259)
[M::mem_pestat] mean and std.dev: (690.25, 427.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4252)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 513, 1643)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4605)
[M::mem_pestat] mean and std.dev: (867.69, 914.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6086)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703686 sequences (100000268 bp) in 1.846 CPU sec, 1.845 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 284299, 26, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (253, 380, 1204)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3106)
[M::mem_pestat] mean and std.dev: (688.50, 654.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4057)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 219, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 658)
[M::mem_pestat] mean and std.dev: (245.35, 120.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 827)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (553, 808, 997)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1885)
[M::mem_pestat] mean and std.dev: (719.30, 430.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2442)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 811)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2103)
[M::mem_pestat] mean and std.dev: (440.87, 495.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2749)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 283730, 24, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 268, 417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 903)
[M::mem_pestat] mean and std.dev: (248.92, 136.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1146)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 219, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 655)
[M::mem_pestat] mean and std.dev: (244.66, 119.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 823)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 662, 3081)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8815)
[M::mem_pestat] mean and std.dev: (1482.67, 1680.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11682)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (264, 385, 1032)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2568)
[M::mem_pestat] mean and std.dev: (535.83, 446.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3336)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704254 reads in 294.009 CPU sec, 9.388 real sec
sorting block 155, #reads = 1069531 mem = 536884782 peak = 1151184896
[M::mem_process_seqs] Processed 703036 reads in 233.274 CPU sec, 7.485 real sec
[M::mem_process_seqs] Processed 703128 reads in 258.773 CPU sec, 8.308 real sec
sorting block 156, #reads = 1069522 mem = 536883503 peak = 1151184896
[M::process] read 702542 sequences (100000096 bp) in 2.594 CPU sec, 2.702 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 283948, 34, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 226, 647)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1637)
[M::mem_pestat] mean and std.dev: (347.70, 319.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2132)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 217, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 648)
[M::mem_pestat] mean and std.dev: (242.76, 118.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 814)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 415, 1385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3841)
[M::mem_pestat] mean and std.dev: (733.24, 759.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5069)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 732, 1096)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2830)
[M::mem_pestat] mean and std.dev: (786.70, 672.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3697)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702486 sequences (100000080 bp) in 2.657 CPU sec, 2.738 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 283371, 38, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 449, 1360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3612)
[M::mem_pestat] mean and std.dev: (900.50, 807.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4738)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 220, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 656)
[M::mem_pestat] mean and std.dev: (245.86, 120.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 824)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (288, 864, 1716)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4572)
[M::mem_pestat] mean and std.dev: (1045.82, 957.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6000)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 320, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 977)
[M::mem_pestat] mean and std.dev: (350.89, 175.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1232)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702756 sequences (100000279 bp) in 2.380 CPU sec, 2.378 real sec...
[M::mem_process_seqs] Processed 703686 reads in 227.628 CPU sec, 7.217 real sec
sorting block 157, #reads = 1067892 mem = 536881136 peak = 1151184896
[M::mem_process_seqs] Processed 702542 reads in 155.975 CPU sec, 4.934 real sec
sorting block 158, #reads = 1068303 mem = 536879839 peak = 1151184896
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 283869, 35, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (260, 362, 926)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2258)
[M::mem_pestat] mean and std.dev: (593.65, 604.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3010)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 221, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 657)
[M::mem_pestat] mean and std.dev: (246.54, 120.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 825)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (294, 714, 2107)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5733)
[M::mem_pestat] mean and std.dev: (981.24, 966.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7546)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 276, 754)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1804)
[M::mem_pestat] mean and std.dev: (433.46, 379.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2329)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702418 sequences (100000087 bp) in 2.959 CPU sec, 3.056 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 283864, 25, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 427, 623)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1501)
[M::mem_pestat] mean and std.dev: (408.30, 269.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1940)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 219, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 647)
[M::mem_pestat] mean and std.dev: (243.93, 118.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 812)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (445, 528, 1482)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3556)
[M::mem_pestat] mean and std.dev: (922.72, 889.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4593)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 305, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 986)
[M::mem_pestat] mean and std.dev: (319.68, 167.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1251)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700610 sequences (100000174 bp) in 2.380 CPU sec, 2.376 real sec...
[M::mem_process_seqs] Processed 702486 reads in 204.464 CPU sec, 6.463 real sec
[M::mem_process_seqs] Processed 702756 reads in 144.149 CPU sec, 4.574 real sec
sorting block 159, #reads = 1071441 mem = 536881427 peak = 1151184896
[M::process] read 699464 sequences (100000046 bp) in 2.586 CPU sec, 2.651 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 283456, 23, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 336, 706)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1624)
[M::mem_pestat] mean and std.dev: (386.96, 243.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2083)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 219, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 641)
[M::mem_pestat] mean and std.dev: (242.91, 116.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 804)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (397, 633, 2195)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5791)
[M::mem_pestat] mean and std.dev: (1120.70, 1050.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7589)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 502, 1530)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4106)
[M::mem_pestat] mean and std.dev: (953.38, 1137.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5505)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699074 sequences (100000024 bp) in 1.776 CPU sec, 1.785 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 282600, 21, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 230, 543)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1361)
[M::mem_pestat] mean and std.dev: (298.89, 244.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1770)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 224, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (248.62, 120.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 830)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 675, 1447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4051)
[M::mem_pestat] mean and std.dev: (993.85, 1169.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5672)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 300, 581)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1333)
[M::mem_pestat] mean and std.dev: (345.72, 206.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1709)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 282141, 23, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 221, 617)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1467)
[M::mem_pestat] mean and std.dev: (376.06, 326.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1892)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 227, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 672)
[M::mem_pestat] mean and std.dev: (252.02, 122.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 844)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (93, 529, 3376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9942)
[M::mem_pestat] mean and std.dev: (1443.26, 1645.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13225)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 303, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 827)
[M::mem_pestat] mean and std.dev: (305.84, 146.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1025)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702418 reads in 296.007 CPU sec, 9.452 real sec
sorting block 160, #reads = 1070579 mem = 536878880 peak = 1151184896
[M::mem_process_seqs] Processed 700610 reads in 233.335 CPU sec, 7.489 real sec
[M::mem_process_seqs] Processed 699464 reads in 258.782 CPU sec, 8.314 real sec
sorting block 161, #reads = 1068132 mem = 536880393 peak = 1151184896
[M::process] read 698470 sequences (100000004 bp) in 3.174 CPU sec, 3.331 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 281951, 20, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 862, 1824)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5052)
[M::mem_pestat] mean and std.dev: (1216.39, 1184.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6666)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 228, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 673)
[M::mem_pestat] mean and std.dev: (252.47, 122.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 845)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (446, 567, 714)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1250)
[M::mem_pestat] mean and std.dev: (503.82, 230.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1518)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 359, 501)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1133)
[M::mem_pestat] mean and std.dev: (344.11, 230.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1449)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698090 sequences (100000296 bp) in 2.497 CPU sec, 2.513 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 282598, 26, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 335, 1112)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2928)
[M::mem_pestat] mean and std.dev: (509.63, 496.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3836)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 230, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 677)
[M::mem_pestat] mean and std.dev: (254.03, 122.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 850)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (553, 672, 957)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1765)
[M::mem_pestat] mean and std.dev: (660.62, 308.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2169)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 268, 601)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1361)
[M::mem_pestat] mean and std.dev: (296.32, 171.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1741)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699074 reads in 202.025 CPU sec, 6.397 real sec
[M::mem_process_seqs] Processed 698470 reads in 142.568 CPU sec, 4.481 real sec
sorting block 162, #reads = 1068147 mem = 536877474 peak = 1151184896
[M::process] read 698410 sequences (100000068 bp) in 2.728 CPU sec, 2.798 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 282425, 27, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 419, 490)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1076)
[M::mem_pestat] mean and std.dev: (310.36, 138.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1369)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 231, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 672)
[M::mem_pestat] mean and std.dev: (253.98, 121.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 843)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 833, 1860)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5132)
[M::mem_pestat] mean and std.dev: (1172.40, 1339.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6768)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (295, 530, 1360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3490)
[M::mem_pestat] mean and std.dev: (759.13, 747.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4555)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698028 sequences (100000243 bp) in 2.541 CPU sec, 2.617 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 281731, 16, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 403, 852)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2160)
[M::mem_pestat] mean and std.dev: (506.73, 465.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2814)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 229, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (252.53, 120.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 838)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (306, 622, 1684)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4440)
[M::mem_pestat] mean and std.dev: (827.44, 720.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5818)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 564, 1805)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5023)
[M::mem_pestat] mean and std.dev: (1118.03, 1306.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6632)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697786 sequences (100000008 bp) in 2.180 CPU sec, 2.176 real sec...
[M::mem_process_seqs] Processed 698090 reads in 204.999 CPU sec, 6.506 real sec
sorting block 163, #reads = 1071444 mem = 536878215 peak = 1151184896
[M::mem_process_seqs] Processed 698410 reads in 139.751 CPU sec, 4.437 real sec
sorting block 164, #reads = 1069693 mem = 536880223 peak = 1151184896
[M::process] read 697248 sequences (100000036 bp) in 2.359 CPU sec, 2.445 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 281643, 30, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 365, 1091)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2785)
[M::mem_pestat] mean and std.dev: (572.73, 533.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3632)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 230, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 662)
[M::mem_pestat] mean and std.dev: (251.83, 119.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 830)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (454, 786, 2149)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5539)
[M::mem_pestat] mean and std.dev: (1206.77, 1079.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7234)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 501, 1323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3471)
[M::mem_pestat] mean and std.dev: (848.16, 773.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4545)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697052 sequences (100000071 bp) in 1.800 CPU sec, 1.799 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 281885, 34, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 347, 1000)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2606)
[M::mem_pestat] mean and std.dev: (539.71, 506.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3409)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 232, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 675)
[M::mem_pestat] mean and std.dev: (254.65, 121.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 847)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (582, 1253, 1637)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3747)
[M::mem_pestat] mean and std.dev: (1120.81, 799.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4802)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 373, 600)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1384)
[M::mem_pestat] mean and std.dev: (376.39, 247.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1776)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 281452, 36, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 345, 939)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2467)
[M::mem_pestat] mean and std.dev: (373.16, 339.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3231)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 232, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 673)
[M::mem_pestat] mean and std.dev: (254.71, 121.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 844)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (284, 695, 1066)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2630)
[M::mem_pestat] mean and std.dev: (711.24, 581.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3412)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 276, 719)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1811)
[M::mem_pestat] mean and std.dev: (446.15, 397.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2357)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698028 reads in 283.488 CPU sec, 9.151 real sec
[M::mem_process_seqs] Processed 697786 reads in 214.874 CPU sec, 6.892 real sec
[M::mem_process_seqs] Processed 697248 reads in 242.819 CPU sec, 7.816 real sec
sorting block 165, #reads = 1068810 mem = 536878875 peak = 1151184896
[M::process] read 697282 sequences (100000021 bp) in 2.692 CPU sec, 2.853 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 281444, 20, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 516, 888)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2134)
[M::mem_pestat] mean and std.dev: (573.10, 434.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2757)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 233, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (256.34, 122.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 852)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (474, 1144, 1730)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4242)
[M::mem_pestat] mean and std.dev: (1054.05, 714.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5498)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 438, 587)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1459)
[M::mem_pestat] mean and std.dev: (393.21, 282.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1895)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 166, #reads = 1069118 mem = 536877416 peak = 1151184896
[M::process] read 696604 sequences (100000186 bp) in 2.447 CPU sec, 2.522 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281774, 29, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 420, 958)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2450)
[M::mem_pestat] mean and std.dev: (629.07, 558.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3196)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 233, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (257.01, 124.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 863)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 791, 1423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3809)
[M::mem_pestat] mean and std.dev: (830.76, 636.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5002)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 555, 1433)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3861)
[M::mem_pestat] mean and std.dev: (870.79, 864.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5075)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697052 reads in 194.840 CPU sec, 6.214 real sec
[M::mem_process_seqs] Processed 697282 reads in 135.959 CPU sec, 4.285 real sec
[M::process] read 696808 sequences (100000070 bp) in 3.228 CPU sec, 3.423 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 281001, 30, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 480, 751)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1893)
[M::mem_pestat] mean and std.dev: (435.70, 382.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2464)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 235, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (259.42, 125.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 869)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (305, 734, 1567)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4091)
[M::mem_pestat] mean and std.dev: (914.00, 871.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5353)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 326, 812)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2068)
[M::mem_pestat] mean and std.dev: (477.67, 469.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2696)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 167, #reads = 1069091 mem = 536881007 peak = 1151184896
[M::process] read 696374 sequences (100000077 bp) in 2.498 CPU sec, 2.577 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 281962, 31, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 341, 986)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2624)
[M::mem_pestat] mean and std.dev: (581.22, 572.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3443)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 235, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 694)
[M::mem_pestat] mean and std.dev: (259.03, 125.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 872)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (275, 862, 1353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3509)
[M::mem_pestat] mean and std.dev: (798.00, 606.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4587)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 500, 1724)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4732)
[M::mem_pestat] mean and std.dev: (941.13, 910.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6236)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 429982 sequences (61598127 bp) in 1.510 CPU sec, 1.516 real sec...
[M::mem_process_seqs] Processed 696604 reads in 188.636 CPU sec, 6.012 real sec
[M::mem_process_seqs] Processed 696808 reads in 133.368 CPU sec, 4.229 real sec
sorting block 168, #reads = 1070795 mem = 536879322 peak = 1151184896
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 280910, 37, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 358, 1576)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4344)
[M::mem_pestat] mean and std.dev: (814.82, 921.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5728)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 235, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (260.00, 126.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 877)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 410, 1242)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3446)
[M::mem_pestat] mean and std.dev: (722.17, 906.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4548)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 372, 1185)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3165)
[M::mem_pestat] mean and std.dev: (740.67, 837.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4155)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 173963, 21, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 250, 531)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1267)
[M::mem_pestat] mean and std.dev: (283.06, 213.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1635)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 231, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 686)
[M::mem_pestat] mean and std.dev: (256.05, 124.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 862)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (462, 573, 1109)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2403)
[M::mem_pestat] mean and std.dev: (662.89, 317.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3050)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 792, 939)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2303)
[M::mem_pestat] mean and std.dev: (670.16, 474.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2985)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696374 reads in 157.795 CPU sec, 5.166 real sec
[M::mem_process_seqs] Processed 429982 reads in 92.522 CPU sec, 3.065 real sec
sorting block 169, #reads = 1069363 mem = 536887051 peak = 1151184896
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000c06f2
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: INTEL(R) XEON(R) PLATINUM 8559C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 181644258
overall: 70457987072 mem 32467.348 user 660.924 sys 1080.242 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1029_HTI-T1-TDNA-1_A23MHWWLT4_1.L004\tPU:L004\tSM:1029_HTI-T1-TDNA-1_A23MHWWLT4_1\tLB:1029_HTI-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1029_HTI-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1029_HTI-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 1080.283 sec; CPU: 33128.275 sec
sorting block 170, #reads = 813542 mem = 409110189 peak = 1179602944
uniq header count 1
merging 171 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000c06f2
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: INTEL(R) XEON(R) PLATINUM 8559C
threads: 31 max 192
algo: util-sort
license: sentieon:util=1
output file size: 10231789484
output reads: 183084373
bam_mem_sort: 171 calls 108.591 user 2.981 sys 111.869 real
bam_write: 171 calls 76.066 user 4.989 sys 91.617 real
execute: 1 calls 59.947 user 1.819 sys 1156.377 real
merge_files: 1 calls 59.917 user 1.789 sys 75.523 real
parse_chunk: 2733 calls 159.726 user 39.476 sys 205.173 real
read_chunk: 7394 calls 92.264 user 53.552 sys 1042.603 real
sort_block: 1 calls 68.075 user 53.077 sys 1008.780 real
write_chunk: 4659 calls 59.379 user 1.369 sys 74.157 real
overall: 3803226112 mem 3027.348 user 135.337 sys 1156.400 real
ls: cannot access '*.cram': No such file or directory